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"name": "rpb2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36594", "map_id": "P36594", "name": "phospho-rpb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC28F2.12", "map_id": "SPBC28F2.12", "name": "phospho-rpb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36595", "map_id": "P36595", "name": "rpb6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1020.04c", "map_id": "SPCC1020.04c", "name": "rpb6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09191", "map_id": "Q09191", "name": "rpb5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23C4.15", "map_id": "SPAC23C4.15", "name": "rpb5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P48011", "map_id": "P48011", "name": "rpc10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19C2.03", "map_id": "SPBC19C2.03", "name": "rpc10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q92399", "map_id": "Q92399", "name": "rpb8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC14C8.12", "map_id": "SPBC14C8.12", "name": "rpb8", "type": "gene_component", "sub_type": "gene", "inferred": 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"compartment_display": "none" }, { "id": "SPCC1442.10c", "map_id": "SPCC1442.10c", "name": "rpb3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74635", "map_id": "O74635", "name": "rpb9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPYUG7.04c", "map_id": "SPAPYUG7.04c", "name": "rpb9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14459", "map_id": "O14459", "name": "rpb7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPACUNK4.06c", "map_id": "SPACUNK4.06c", "name": "rpb7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_6781829", "map_id": "CHEBI:17972", "name": "ribonucleoside triphosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10750119", "map_id": "none", "name": "Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_113541", "map_id": "CHEBI:33019", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10750235", "map_id": "none", "name": "UVSSA:USP7 deubiquitinates ERCC6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113518", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10750226", "map_id": "none", "name": "Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P49373", "map_id": "P49373", "name": "tfs1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC20H4.03c", "map_id": "SPAC20H4.03c", "name": "tfs1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09879", "map_id": "Q09879", "name": "ubp5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC188.08c", "map_id": "SPCC188.08c", "name": "ubp5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59753", "map_id": "O59753", "name": "rhp14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC649.03", "map_id": "SPBC649.03", "name": "rhp14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7R9", "map_id": "Q9P7R9", "name": "cwf3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC211.02c", "map_id": "SPBC211.02c", "name": "cwf3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94508", "map_id": "O94508", "name": "cwf11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.02", "map_id": "SPBC646.02", "name": "cwf11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74370", "map_id": "O74370", "name": "cwf12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC32F12.05c", "map_id": "SPBC32F12.05c", "name": "cwf12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7V2", "map_id": "Q9Y7V2", "name": "bye1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC645.13", "map_id": "SPCC645.13", "name": "bye1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14011", "map_id": "O14011", "name": "prp19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC29A4.08c", "map_id": "SPAC29A4.08c", "name": "prp19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750232", "map_id": "none", "name": "TC-NER pre-incision complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750182", "map_id": "none", "name": "ERCC6 binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10750127", "map_id": "Q9UR24", "name": "rhp26", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10739167", "map_id": "none", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739153", "map_id": "none", "name": "Lsm1-7 Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74499", "map_id": "O74499", "name": "lsm7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC285.12", "map_id": "SPCC285.12", "name": "lsm7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94408", "map_id": "O94408", "name": "lsm2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1620.01c", "map_id": "SPCC1620.01c", "name": "lsm2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7M4", "map_id": "Q9Y7M4", "name": "lsm3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC9B6.05c", "map_id": "SPBC9B6.05c", "name": "lsm3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42978", "map_id": "O42978", "name": "lsm5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC20F10.09", "map_id": "SPBC20F10.09", "name": "lsm5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUI1", "map_id": "Q9UUI1", "name": "lsm6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2F3.17c", "map_id": "SPAC2F3.17c", "name": "lsm6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42958", "map_id": "O42958", "name": "PATL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19G7.10c", "map_id": "SPBC19G7.10c", "name": "PATL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87173", "map_id": "P87173", "name": "lsm1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3D6.08c", "map_id": "SPBC3D6.08c", "name": "lsm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14352", "map_id": "O14352", "name": "lsm4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC30D10.06", "map_id": "SPBC30D10.06", "name": "lsm4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_429974", "map_id": "none", "name": "mature mRNA (eukaryotic, capped and deadenylated)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739155", "map_id": "none", "name": "Deadenylated mRNA:Lsm1-7 Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10739245", "map_id": "none", "name": "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_109395", "map_id": "CHEBI:60377", "name": "CMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_109402", "map_id": "CHEBI:57865", "name": "UMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_429926", "map_id": "none", "name": "capped oligoribonucleotide", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76577", "map_id": "CHEBI:456215", "name": "AMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113578", "map_id": "CHEBI:58115", "name": "GMP", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739242", "map_id": "none", "name": "Exosome:SKI complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42872", "map_id": "O42872", "name": "ski6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3G9.10c", "map_id": "SPAC3G9.10c", "name": "ski6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59821", "map_id": "O59821", "name": "csl4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1840.11", "map_id": "SPCC1840.11", "name": "csl4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94474", "map_id": "O94474", "name": "ski3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1919.05", "map_id": "SPCC1919.05", "name": "ski3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74774", "map_id": "O74774", "name": "hbs1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC25B2.01", "map_id": "SPBC25B2.01", "name": "hbs1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13903", "map_id": "O13903", "name": "rrp40", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22A12.12c", "map_id": "SPAC22A12.12c", "name": "rrp40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09150", "map_id": "Q09150", "name": "rec14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC32F12.02", "map_id": "SPBC32F12.02", "name": "rec14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74918", "map_id": "O74918", "name": "rrp45", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC757.08", "map_id": "SPCC757.08", "name": "rrp45", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60124", "map_id": "O60124", "name": "rrp42", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16G5.10", "map_id": "SPBC16G5.10", "name": "rrp42", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7R3", "map_id": "Q9P7R3", "name": "mtr3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC211.08c", "map_id": "SPBC211.08c", "name": "mtr3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59801", "map_id": "O59801", "name": "SKIV2L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC550.03c", "map_id": "SPCC550.03c", "name": "SKIV2L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09704", "map_id": "Q09704", "name": "rrp4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2F7.14c", "map_id": "SPAC2F7.14c", "name": "rrp4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42894", "map_id": "O42894", "name": "rrp46", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC115.01c", "map_id": "SPBC115.01c", "name": "rrp46", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10205", "map_id": "Q10205", "name": "rrp43", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17D1.03c", "map_id": "SPBC17D1.03c", "name": "rrp43", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P37202", "map_id": "P37202", "name": "dis3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC26H8.10", "map_id": "SPBC26H8.10", "name": "dis3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739165", "map_id": "none", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_429925", "map_id": "none", "name": "oligoribonucleotide with a 5'-diphosphate", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_430042", "map_id": "CHEBI:17825", "name": "7MGMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739162", "map_id": "Q9P7C9", "name": "nhm1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBP4H10.20", "map_id": "SPBP4H10.20", "name": "nhm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10733646", "map_id": "none", "name": "Recognition of AAUAAA sequence by CPSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733642", "map_id": "none", "name": "capped intronless pre-mRNA:CBC complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9P383", "map_id": "Q9P383", "name": "cbc2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC13A2.01c", "map_id": "SPBC13A2.01c", "name": "cbc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14253", "map_id": "O14253", "name": "cbc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6G10.07", "map_id": "SPAC6G10.07", "name": "cbc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10731317", "map_id": "none", "name": "CPSF", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9UTD1", "map_id": "Q9UTD1", "name": "yth1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC227.08c", "map_id": "SPAC227.08c", "name": "yth1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74733", "map_id": "O74733", "name": "cft1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1709.08", "map_id": "SPBC1709.08", "name": "cft1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UTN4", "map_id": "Q9UTN4", "name": "pfs2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC12G12.14c", "map_id": "SPAC12G12.14c", "name": "pfs2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13794", "map_id": "O13794", "name": "ysh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17G6.16c", "map_id": "SPAC17G6.16c", "name": "ysh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09801", "map_id": "Q09801", "name": "FIP1L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22G7.10", "map_id": "SPAC22G7.10", "name": "FIP1L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74740", "map_id": "O74740", "name": "cft2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1709.15c", "map_id": "SPBC1709.15c", "name": "cft2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733644", "map_id": "none", "name": "CPSF:capped intronless pre-mRNA:CBC complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10757633", "map_id": "none", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10757563", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "O43046", "map_id": "O43046", "name": "vma7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B9.18c", "map_id": "SPBC3B9.18c", "name": "vma7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14046", "map_id": "O14046", "name": "vma16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2C4.13", "map_id": "SPAC2C4.13", "name": "vma16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P31406", "map_id": "P31406", "name": "vma1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC343.05", "map_id": "SPAC343.05", "name": "vma1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87141", "map_id": "P87141", "name": "mip1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC57A7.11", "map_id": "SPAC57A7.11", "name": "mip1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P31411", "map_id": "P31411", "name": "vma2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC637.05c", "map_id": "SPAC637.05c", "name": "vma2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13753", "map_id": "O13753", "name": "vma6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17A2.03c", "map_id": "SPAC17A2.03c", "name": "vma6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13687", "map_id": "O13687", "name": "vma4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC11E3.07", "map_id": "SPAC11E3.07", "name": "vma4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29438", "map_id": "CHEBI:37565", "name": "GTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "Q9HDW6", "map_id": "Q9HDW6", "name": "vma5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB2B4.05", "map_id": "SPAPB2B4.05", "name": "vma5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29420", "map_id": "CHEBI:58189", "name": "GDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P50515", "map_id": "P50515", "name": "vma3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1B3.14", "map_id": "SPAC1B3.14", "name": "vma3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74544", "map_id": "O74544", "name": "gtr2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC777.05", "map_id": "SPCC777.05", "name": "gtr2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14265", "map_id": "O14265", "name": "vma13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC7D4.10", "map_id": "SPAC7D4.10", "name": "vma13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74174", "map_id": "O74174", "name": "vma10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1289.05c", "map_id": "SPBC1289.05c", "name": "vma10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74824", "map_id": "O74824", "name": "gtr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC337.13c", "map_id": "SPBC337.13c", "name": "gtr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59823", "map_id": "O59823", "name": "vma8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC965.03", "map_id": "SPCC965.03", "name": "vma8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13742", "map_id": "O13742", "name": "vph1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC16E8.07c", "map_id": "SPAC16E8.07c", "name": "vph1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q69Z14", "map_id": "Q69Z14", "name": "vma9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1685.16", "map_id": "SPBC1685.16", "name": "vma9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7J2", "map_id": "Q9Y7J2", "name": "LAMTOR2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1778.05c", "map_id": "SPBC1778.05c", "name": "LAMTOR2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735183", "map_id": "none", "name": "RHEB:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "O94363", "map_id": "O94363", "name": "rhb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC428.16c", "map_id": "SPBC428.16c", "name": "rhb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757565", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10757544", "map_id": "none", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10757537", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10757541", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10757608", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10757552", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10757561", "map_id": "none", "name": "mTORC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757570", "map_id": "none", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10757567", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10757557", "map_id": "none", "name": "RRAGA,B exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10757550", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_29468", "map_id": "CHEBI:32682", "name": "L-Arg", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10757554", "map_id": "none", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10757606", "map_id": "none", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "reaction_10733230", "map_id": "none", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500006", "map_id": "none", "name": "(d)CDP, UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_110094", "map_id": "CHEBI:58069", "name": "CDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "CHEBI:58593", "map_id": "CHEBI:58593", "name": "CHEBI:58593", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500009", "map_id": "none", "name": "(d)CMP, UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_109378", "map_id": "CHEBI:57566", "name": "dCMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_418075", "map_id": "CHEBI:57865", "name": "UMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10732253", "map_id": "O59771", "name": "CMPK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC1795.05c", "map_id": "SPCC1795.05c", "name": "CMPK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740122", "map_id": "none", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_482803", "map_id": "none", "name": "(d)NDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:60471", "map_id": "CHEBI:60471", "name": "CHEBI:60471", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:58369", "map_id": "CHEBI:58369", "name": "CHEBI:58369", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:58595", "map_id": "CHEBI:58595", "name": "CHEBI:58595", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:57667", "map_id": "CHEBI:57667", "name": "CHEBI:57667", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113593", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_482807", "map_id": "none", "name": "(d)NTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_29494", "map_id": "CHEBI:46398", "name": "UTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_500739", "map_id": "CHEBI:61555", "name": "dUTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_29892", "map_id": "CHEBI:61429", "name": "dGTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_110644", "map_id": "CHEBI:61404", "name": "dATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_30185", "map_id": "CHEBI:61481", "name": "dCTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_30187", "map_id": "CHEBI:37568", "name": "dTTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_110614", "map_id": "CHEBI:37563", "name": "CTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113581", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10740119", "map_id": "none", "name": "NME4 hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P49740", "map_id": "P49740", "name": "ndk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC806.07", "map_id": "SPAC806.07", "name": "ndk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732360", "map_id": "none", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29472", "map_id": "CHEBI:58359", "name": "L-Gln", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_70106", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29404", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732357", "map_id": "none", "name": "CTPS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42644", "map_id": "O42644", "name": "ura7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC10F6.03c", "map_id": "SPAC10F6.03c", "name": "ura7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750485", "map_id": "none", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_6788813", "map_id": "none", "name": "(d)NMPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_109386", "map_id": "CHEBI:58245", "name": "2'-deoxyadenosine 5'-monophosphate", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29358", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_113582", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_6788807", "map_id": "none", "name": "(d)NDPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10750482", "map_id": "Q9UU88", "name": "AK6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPCC830.11c", "map_id": "SPCC830.11c", "name": "AK6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734110", "map_id": "none", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8866401", "map_id": "CHEBI:57930", "name": "NDP(3-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732350", "map_id": "O94504", "name": "trx2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC12D12.07c", "map_id": "SPBC12D12.07c", "name": "trx2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10732348", "map_id": "O94504", "name": "trx2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8866399", "map_id": "CHEBI:73316", "name": "dNDP(3-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734107", "map_id": "none", "name": "RNR (M1M2)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P36603", "map_id": "P36603", "name": "suc22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC25D12.04", "map_id": "SPBC25D12.04", "name": "suc22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36602", "map_id": "P36602", "name": "cdc22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1F7.05", "map_id": "SPAC1F7.05", "name": "cdc22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:29034", "map_id": "CHEBI:29034", "name": "CHEBI:29034", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734119", "map_id": "none", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734116", "map_id": "none", "name": "RNR (M1M2B)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10740066", "map_id": "none", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_482625", "map_id": "none", "name": "(d)NTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_482627", "map_id": "none", "name": "(d)NDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10740061", "map_id": "none", "name": "nucleoside diphosphate kinase 1A:5B heterohexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10733852", "map_id": "none", "name": "AMP + ATP <=> ADP + ADP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733847", "map_id": "P33075", "name": "adk1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "SPAC4G9.03", "map_id": "SPAC4G9.03", "name": "adk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732370", "map_id": "none", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_500742", "map_id": "CHEBI:246422", "name": "dUMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_9668967", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10732367", "map_id": "none", "name": "DUT trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9P6Q5", "map_id": "Q9P6Q5", "name": "DUT-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC644.05c", "map_id": "SPAC644.05c", "name": "DUT-2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732510", "map_id": "none", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500071", "map_id": "none", "name": "(d)GMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_109327", "map_id": "CHEBI:57673", "name": "dGMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29626", "map_id": "CHEBI:58115", "name": "GMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_500077", "map_id": "none", "name": "(d)GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10732507", "map_id": "Q9P6I5", "name": "GUK1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC1198.05", "map_id": "SPBC1198.05", "name": "GUK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10752646", "map_id": "none", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6806881", "map_id": "CHEBI:61557", "name": "NTP(4-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10752643", "map_id": "none", "name": "NME1:NME3 heterohexamer, NME2P1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10732322", "map_id": "none", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_109382", "map_id": "CHEBI:246422", "name": "dUMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_31633", "map_id": "CHEBI:28938", "name": "NH4+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732319", "map_id": "none", "name": "DCTD hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O43012", "map_id": "O43012", "name": "DCTD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2G2.13c", "map_id": "SPBC2G2.13c", "name": "DCTD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732332", "map_id": "none", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111355", "map_id": "CHEBI:57453", "name": "THF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_109366", "map_id": "CHEBI:63528", "name": "TMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_73604", "map_id": "CHEBI:57451", "name": "DHF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732329", "map_id": "none", "name": "TS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UTI7", "map_id": "Q9UTI7", "name": "TYMS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC15E1.04", "map_id": "SPAC15E1.04", "name": "TYMS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740131", "map_id": "none", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740128", "map_id": "none", "name": "CTPS2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10733843", "map_id": "none", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6788782", "map_id": "none", "name": "(d)NDPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_6788778", "map_id": "none", "name": "(d)NMPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10733838", "map_id": "P33075", "name": "adk1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10733845", "map_id": "none", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10730480", "map_id": "none", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29364", "map_id": "CHEBI:57783", "name": "NADPH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111745", "map_id": "CHEBI:58297", "name": "GSSG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29366", "map_id": "CHEBI:58349", "name": "NADP+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29450", "map_id": "CHEBI:57925", "name": "GSH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730477", "map_id": "none", "name": "GSR-2:FAD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78965", "map_id": "P78965", "name": "pgr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17A3.07", "map_id": "SPBC17A3.07", "name": "pgr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113596", "map_id": "CHEBI:16238", "name": "FAD", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10739090", "map_id": "none", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739086", "map_id": "Q09892", "name": "sty1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC24B11.06c", "map_id": "SPAC24B11.06c", "name": "phospho-sty1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10739088", "map_id": "Q09892", "name": "phospho-sty1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734141", "map_id": "none", "name": "G protein alpha:GTP complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q04665", "map_id": "Q04665", "name": "gpa2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23H3.13c", "map_id": "SPAC23H3.13c", "name": "gpa2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739107", "map_id": "none", "name": "Phosphorylation of cPLA2 by MAPK p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739104", "map_id": "none", "name": "Homologues of PLA2G4A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78854", "map_id": "P78854", "name": "phospho-plb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1A6.04c", "map_id": "SPAC1A6.04c", "name": "phospho-plb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13857", "map_id": "O13857", "name": "phospho-p-S505,S727-PLA2G4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1450.09c", "map_id": "SPCC1450.09c", "name": "phospho-p-S505,S727-PLA2G4A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UTH5", "map_id": "Q9UTH5", "name": "phospho-p-S505,S727-PLA2G4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CU03", "map_id": "P0CU03", "name": "phospho-p-S505,S727-PLA2G4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CU02", "map_id": "P0CU02", "name": "phospho-p-S505,S727-PLA2G4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7N6", "map_id": "Q9Y7N6", "name": "phospho-p-S505,S727-PLA2G4A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734190", "map_id": "none", "name": "Homologues of p-S505,S727-PLA2G4A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10732235", "map_id": "none", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10732216", "map_id": "none", "name": "60S ribosomal complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9URX6", "map_id": "Q9URX6", "name": "rpl31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC890.08", "map_id": "SPAC890.08", "name": "rpl31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P05767", "map_id": "P05767", "name": "rpl39", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC663.04", "map_id": "SPCC663.04", "name": "rpl39", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14363", "map_id": "O14363", "name": "rpl102", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC30D10.18c", "map_id": "SPBC30D10.18c", "name": "rpl102", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94658", "map_id": "O94658", "name": "rpl3602", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC405.07", "map_id": "SPBC405.07", "name": "rpl3602", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78946", "map_id": "P78946", "name": "rpl26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29B5.03c", "map_id": "SPBC29B5.03c", "name": "rpl26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8TFH1", "map_id": "Q8TFH1", "name": "rpl1802", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB17E12.13", "map_id": "SPAPB17E12.13", "name": "rpl1802", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13672", "map_id": "O13672", "name": "rpl8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29A3.04", "map_id": "SPBC29A3.04", "name": "rpl8", "type": 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For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10732231", "map_id": "none", "name": "80S:Met-tRNAi:mRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10732229", "map_id": "none", "name": "eIF5B:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10734743", "map_id": "none", "name": "Formation of translation initiation complexes containing mRNA that does not circularize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731755", "map_id": "P55877", "name": "tif11", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC25H2.07", "map_id": "SPBC25H2.07", "name": "tif11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10731778", "map_id": "none", "name": "43S complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94513", "map_id": "O94513", "name": "int6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.09c", "map_id": "SPBC646.09c", "name": "int6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09130", "map_id": "Q09130", "name": "tif213", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17G9.09", "map_id": "SPBC17G9.09", "name": "tif213", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43060", "map_id": "O43060", "name": "eif3f", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4C3.07", "map_id": "SPBC4C3.07", "name": "eif3f", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UT48", "map_id": "Q9UT48", "name": "eif3h", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC821.05", "map_id": "SPAC821.05", "name": "eif3h", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P56329", "map_id": "P56329", "name": "tif212", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC32A11.04c", "map_id": "SPAC32A11.04c", "name": "tif212", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10425", "map_id": "Q10425", "name": "EIF3B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC25G10.08", "map_id": "SPAC25G10.08", "name": "EIF3B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94236", "map_id": "O94236", "name": "moe1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC637.07", "map_id": "SPAC637.07", "name": "moe1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P56286", "map_id": "P56286", "name": "tif211", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3G9.09c", "map_id": "SPAC3G9.09c", "name": "tif211", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74760", "map_id": "O74760", "name": "tif32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17D11.05", "map_id": "SPBC17D11.05", "name": "tif32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14164", "map_id": "O14164", "name": "nip1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4A8.16c", "map_id": "SPAC4A8.16c", "name": "nip1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87128", "map_id": "P87128", "name": "EIF3J", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3A12.13c", "map_id": "SPAC3A12.13c", "name": "EIF3J", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P55877", "map_id": "P55877", "name": "tif11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09722", "map_id": "Q09722", "name": "eif3m", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1751.03", "map_id": "SPAC1751.03", "name": "eif3m", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79083", "map_id": "P79083", "name": "sum1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4D7.05", "map_id": "SPAC4D7.05", "name": "sum1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78795", "map_id": "P78795", "name": "phospho-tif35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC18H10.03", "map_id": "SPBC18H10.03", "name": "phospho-tif35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734741", "map_id": "none", "name": "mRNA:eIF4F:eIF4B:eIF4H", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74743", "map_id": "O74743", "name": "tif452", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1709.18", "map_id": "SPBC1709.18", "name": "tif452", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14369", "map_id": "O14369", "name": "sce3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC18H10.04c", "map_id": "SPBC18H10.04c", "name": "sce3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10475", "map_id": "Q10475", "name": "tif471", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17C9.03", "map_id": "SPAC17C9.03", "name": "tif471", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P47943", "map_id": "P47943", "name": "tif1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1006.07", "map_id": "SPAC1006.07", "name": "tif1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10731810", "map_id": "none", "name": "48S complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10734671", "map_id": "none", "name": "Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734667", "map_id": "none", "name": "Homologues of PABPC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P6M8", "map_id": "Q9P6M8", "name": "crp79", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1610.03c", "map_id": "SPAC1610.03c", "name": "crp79", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P31209", "map_id": "P31209", "name": "pab1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC57A7.04c", "map_id": "SPAC57A7.04c", "name": "pab1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734655", "map_id": "none", "name": "Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10734669", "map_id": "none", "name": "43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10732241", "map_id": "none", "name": "eIF3 and eIF1A bind to the 40S subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731750", "map_id": "none", "name": "eIF3 subunits complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10731692", "map_id": "none", "name": "40S ribosomal complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10732239", "map_id": "none", "name": "40S:eIF3:eIF1A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10731821", "map_id": "none", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_72617", "map_id": "none", "name": "eIF1", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10732237", "map_id": "none", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10732218", "map_id": "none", "name": "80S ribosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10731831", "map_id": "none", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731774", "map_id": "none", "name": "eIF2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_72393", "map_id": "none", "name": "Met-tRNAi", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10731776", "map_id": "none", "name": "ternary complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10731823", "map_id": "none", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731789", "map_id": "none", "name": "eIF4A subunits complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10731794", "map_id": "O74743", "name": "tif452", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10731799", "map_id": "Q10475", "name": "tif471", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10731801", "map_id": "none", "name": "eIF4F", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10731829", "map_id": "none", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731772", "map_id": "none", "name": "EIF2S1:EIF2S2:EIF2S3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10732248", "map_id": "none", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731860", "map_id": "none", "name": "eIF2:GDP: eIF2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P56288", "map_id": "P56288", "name": "tif223", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4D7.09", "map_id": "SPAC4D7.09", "name": "tif223", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UT76", "map_id": "Q9UT76", "name": "tif222", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC343.14c", "map_id": "SPAC343.14c", "name": "tif222", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P56287", "map_id": "P56287", "name": "tif225", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC8C9.15c", "map_id": "SPAC8C9.15c", "name": "tif225", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USP0", "map_id": "Q9USP0", "name": "tif221", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC11E10.07c", "map_id": "SPCC11E10.07c", "name": "tif221", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09924", "map_id": "Q09924", "name": "tif224", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC21E11.06", "map_id": "SPAC21E11.06", "name": "tif224", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10731858", "map_id": "none", "name": "eIF2B subunits complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10731862", "map_id": "none", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731819", "map_id": "none", "name": "eIF2:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10732245", "map_id": "none", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731815", "map_id": "Q09689", "name": "tif5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC2F7.05c", "map_id": "SPAC2F7.05c", "name": "tif5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732243", "map_id": "none", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10738284", "map_id": "none", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_389545", "map_id": "CHEBI:151", "name": "ISCIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113528", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29406", "map_id": "CHEBI:16810", "name": "2OG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10738281", "map_id": "none", "name": "IDH1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14254", "map_id": "O14254", "name": "idp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6G10.08", "map_id": "SPAC6G10.08", "name": "idp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734757", "map_id": "none", "name": "Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10734069", "map_id": "none", "name": "Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9Y8G3", "map_id": "Q9Y8G3", "name": "mex67", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1921.03c", "map_id": "SPBC1921.03c", "name": "mex67", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9URV0", "map_id": "Q9URV0", "name": "CHTOP", "type": "complex_component", "sub_type": "protein_component", 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"inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC13A2.02", "map_id": "SPBC13A2.02", "name": "nup82", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94319", "map_id": "O94319", "name": "sec13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC215.15", "map_id": "SPBC215.15", "name": "sec13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09793", "map_id": "Q09793", "name": "nup45", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22G7.09c", "map_id": "SPAC22G7.09c", "name": "nup45", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43044", "map_id": "O43044", "name": "nup120", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B9.16c", "map_id": "SPBC3B9.16c", "name": "nup120", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734749", "map_id": "none", "name": "Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10733677", "map_id": "none", "name": "Nucleoplasmic mature intronless derived mRNA:TAP:Aly/Ref complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10734747", "map_id": "none", "name": "Mature intronless derived mRNA:TAP:Aly/Ref complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10733679", "map_id": "none", "name": "Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733165", "map_id": "Q9Y8G3", "name": "mex67", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10733675", "map_id": "none", "name": "Mature intronless derived mRNA complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10730903", "map_id": "Q9URV0", "name": "ALYREF", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10730621", "map_id": "none", "name": "Cap Binding Complex (CBC)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733226", "map_id": "none", "name": "Transport of the export-competent mRNP complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10733177", "map_id": "none", "name": "NPC:NXF1,2:NXT1:EJC:CBC:mRNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O43037", "map_id": "O43037", "name": "mnh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B9.08c", "map_id": "SPBC3B9.08c", "name": "mnh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94403", "map_id": "O94403", "name": "CHTOP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10267", "map_id": "Q10267", "name": "upf3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13G7.03", "map_id": "SPAC13G7.03", "name": "upf3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10055", "map_id": "Q10055", "name": "tif412", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1F5.10", "map_id": "SPAC1F5.10", "name": "tif412", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q1MTR2", "map_id": "Q1MTR2", "name": "RNPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC13G1.14c", "map_id": "SPBC13G1.14c", "name": "RNPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CAN8", "map_id": "P0CAN8", "name": "nxt1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB1A10.03", "map_id": "SPAPB1A10.03", "name": "nxt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733219", "map_id": "none", "name": "NPC:NXF1:NXT1:EJC:CBC:mRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10733224", "map_id": "O94652", "name": "gle1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC31E1.05", "map_id": "SPBC31E1.05", "name": "gle1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734071", "map_id": "none", "name": "Docking of Mature Histone mRNA complex:TAP at the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734067", "map_id": "none", "name": "Mature intronless transcript derived Histone pre-mRNA:CBC complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734761", "map_id": "none", "name": "Release of the SLBP independent Histone mRNA from the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734759", "map_id": "none", "name": "Mature SLBP independent Histone mRNA:eIF4E complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10733187", "map_id": "Q9Y8G3", "name": "mex67", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10733203", "map_id": "Q9URV0", "name": "ALYREF", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10734766", "map_id": "none", "name": "NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733169", "map_id": "none", "name": "NXF1,2:NXT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10731417", "map_id": "none", "name": "polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9P7J4", "map_id": "Q9P7J4", "name": "mft1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC24B10.11c", "map_id": "SPCC24B10.11c", "name": "mft1", "type": "gene_component", 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"notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734751", "map_id": "none", "name": "Mature Intronless Transcript Derived mRNA:eIF4E Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746231", "map_id": "none", "name": "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746219", "map_id": "none", "name": "p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P09988", "map_id": "P09988", "name": "hht1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1834.04", "map_id": "SPAC1834.04", "name": "hht1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P09322", "map_id": "P09322", "name": "hhf3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", 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"compartment_display": "none" }, { "id": "P04913", "map_id": "P04913", "name": "htb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC622.09", "map_id": "SPCC622.09", "name": "htb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_469662", "map_id": "CHEBI:16330", "name": "DHTEST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193079", "map_id": "CHEBI:16422", "name": "ANDST", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "P48003", "map_id": "P48003", "name": "pht1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC11B10.10c", "map_id": "SPBC11B10.10c", "name": "pht1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P04909", "map_id": "P04909", "name": "hta1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC622.08c", "map_id": "SPCC622.08c", "name": "hta1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_193057", "map_id": "CHEBI:17347", "name": "TEST", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:29117", "map_id": "CHEBI:29117", "name": "CHEBI:29117", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36582", "map_id": "P36582", "name": "pck1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17G8.14c", "map_id": "SPAC17G8.14c", "name": "pck1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746228", "map_id": "none", "name": "p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746240", "map_id": "none", "name": "Demethylase KDM4C binds KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746236", "map_id": "O94691", "name": "jmj3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC83.07", "map_id": "SPBC83.07", "name": "jmj3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746238", "map_id": "none", "name": "p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O94691", "map_id": "O94691", "name": "jmj3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746249", "map_id": "none", "name": "KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113671", "map_id": "CHEBI:16810", "name": "2OG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_113685", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_159942", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_159939", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_29478", "map_id": "CHEBI:16842", "name": "CH2O", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10746246", "map_id": "none", "name": "p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10740388", "map_id": "none", "name": "Binding of ERp57", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10740236", "map_id": "Q10057", "name": "PDIA3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "SPAC1F5.02", "map_id": "SPAC1F5.02", "name": "PDIA3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740384", "map_id": "none", "name": "unfolded protein:(Glc)1 (GlcNAc)2 (Man)9 (Asn)1:chaperone", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "Q9P7D0", "map_id": "Q9P7D0", "name": "CANX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP4H10.19c", "map_id": "SPBP4H10.19c", "name": "CANX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36581", "map_id": "P36581", "name": "cal1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3C7.11c", "map_id": "SPAC3C7.11c", "name": "cal1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:59080", "map_id": "CHEBI:59080", "name": "CHEBI:59080", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740386", "map_id": "none", "name": "unfolded protein:(Glc)1 (GlcNAc)2 (Man)9 (Asn)1:chaperone:ERp57", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "true" }, { "id": "Q10057", "map_id": "Q10057", "name": "PDIA3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741489", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741485", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_927893", "compartment_display": "endoplasmic reticulum quality control compartment", "complex": "true" }, { "id": "species_10741487", "map_id": "none", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:59092", "map_id": "CHEBI:59092", "name": "CHEBI:59092", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:60627", "map_id": "CHEBI:60627", "name": "CHEBI:60627", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:59087", "map_id": "CHEBI:59087", "name": "CHEBI:59087", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:60629", "map_id": "CHEBI:60629", "name": "CHEBI:60629", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:60628", "map_id": "CHEBI:60628", "name": "CHEBI:60628", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750397", "map_id": "none", "name": "Degradation of PCSK9:LDLR:Clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1660541", "compartment_display": "endolysosome membrane" }, { "id": "species_10750393", "map_id": "none", "name": "PCSK9:LDLR:Clathrin:AP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1660541", "compartment_display": "endolysosome membrane", "complex": "true" }, { "id": "Q9USP6", "map_id": "Q9USP6", "name": "clc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC9B6.08", "map_id": "SPBC9B6.08", "name": "clc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10161", "map_id": "Q10161", "name": "chc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26A3.05", "map_id": "SPAC26A3.05", "name": "chc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09718", "map_id": "Q09718", "name": "apm4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC31A2.09c", "map_id": "SPAC31A2.09c", "name": "apm4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7L6", "map_id": "Q9Y7L6", "name": "aps2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC685.04c", "map_id": "SPBC685.04c", "name": "aps2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43079", "map_id": "O43079", "name": "apl2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC947.02", "map_id": "SPBC947.02", "name": "apl2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43005", "map_id": "O43005", "name": "apl1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2G2.06c", "map_id": "SPBC2G2.06c", "name": "apl1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9C0W7", "map_id": "Q9C0W7", "name": "apl3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC691.03c", "map_id": "SPBC691.03c", "name": "apl3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40903", "map_id": "P40903", "name": "isp6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4A8.04", "map_id": "SPAC4A8.04", "name": "isp6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750391", "map_id": "none", "name": "Clathrin:AP2 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10750395", "map_id": "none", "name": "PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1660541", "compartment_display": "endolysosome membrane" }, { "id": "species_10750361", "map_id": "none", "name": "PCSK9:LDLR:Clathrin:AP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10754372", "map_id": "none", "name": "VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10754362", "map_id": "none", "name": "VLDL:PCSK9:Clathrin:AP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10754370", "map_id": "none", "name": "VLDL:PCSK9:Clathrin:AP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10753477", "map_id": "none", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_163579", "map_id": "CHEBI:17002", "name": "CHEST", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13977", "compartment_display": "lipid droplet", "complex": "false" }, { "id": "species_216762", "map_id": "CHEBI:16113", "name": "CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "false" }, { "id": "species_8876730", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10753474", "map_id": "none", "name": "Homologues of NCEH1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9US38", "map_id": "Q9US38", "name": "NCEH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB1A11.02", "map_id": "SPAPB1A11.02", "name": "NCEH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9HDX3", "map_id": "Q9HDX3", "name": "NCEH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735593", "map_id": "none", "name": "AHCY:NAD+ tetramer hydrolyses AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_71285", "map_id": "CHEBI:57856", "name": "AdoHcy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_174369", "map_id": "CHEBI:17230", "name": "HCYS", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_83909", "map_id": "CHEBI:16335", "name": "Ade-Rib", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10735590", "map_id": "none", "name": "AHCY:NAD+ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13639", "map_id": "O13639", "name": "AHCY", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC8D2.18c", "map_id": "SPBC8D2.18c", "name": "AHCY", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113526", "map_id": "CHEBI:57540", "name": "NAD+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10735568", "map_id": "none", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174390", "map_id": "CHEBI:57844", "name": "L-Met", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_71284", "map_id": "CHEBI:59789", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735565", "map_id": "none", "name": "MAT1A multimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O60198", "map_id": "O60198", "name": "sam1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC14F5.05c", "map_id": "SPBC14F5.05c", "name": "sam1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_74126", "map_id": "CHEBI:29103", "name": "K+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10752211", "map_id": "none", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6806829", "map_id": "CHEBI:17826", "name": "MMAIII", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6800127", "map_id": "CHEBI:48765", "name": "DMAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10752205", "map_id": "none", "name": "N6AMT1:TRMT112", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UT94", "map_id": "Q9UT94", "name": "mtq2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC323.05c", "map_id": "SPAC323.05c", "name": "mtq2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09723", "map_id": "Q09723", "name": "trm112", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC31A2.02", "map_id": "SPAC31A2.02", "name": "trm112", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735665", "map_id": "none", "name": "COMT transfer CH3 from AdoMet to 3,4DHBNZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_175977", "map_id": "CHEBI:36062", "name": "3,4DHBNZ", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_175978", "map_id": "CHEBI:63797", "name": "3H,4MBNZ", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735662", "map_id": "none", "name": "Homologues of COMT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8NKC1", "map_id": "Q8NKC1", "name": "LRTOMT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBPB21E7.04c", "map_id": "SPBPB21E7.04c", "name": "LRTOMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42898", "map_id": "O42898", "name": "LRTOMT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756481", "map_id": "none", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_111793", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10743943", "map_id": "O60184", "name": "ssn6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC23E6.09", "map_id": "SPBC23E6.09", "name": "ssn6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743945", "map_id": "none", "name": "KDM6B:Fe2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_113531", "map_id": "CHEBI:29033", "name": "Fe2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "O60184", "map_id": "O60184", "name": "ssn6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743957", "map_id": "none", "name": "ROS oxidize thioredoxin and activate MAP3K5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1250243", "map_id": "CHEBI:26523", "name": "ROS", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10743955", "map_id": "none", "name": "MAP3K5:TXN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P28829", "map_id": "P28829", "name": "byr2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1D7.05", "map_id": "SPBC1D7.05", "name": "byr2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94504", "map_id": "O94504", "name": "trx2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743953", "map_id": "P28829", "name": "byr2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10739760", "map_id": "none", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739740", "map_id": "none", "name": "p-S189,T193-MAP2K3, p-S207,T211-MAP2K6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P10506", "map_id": "P10506", "name": "phospho-byr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1D4.13", "map_id": "SPAC1D4.13", "name": "phospho-byr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y884", "map_id": "Q9Y884", "name": "phospho-skh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC543.07", "map_id": "SPBC543.07", "name": "phospho-skh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P33886", "map_id": "P33886", "name": "phospho-wis1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC409.07c", "map_id": "SPBC409.07c", "name": "phospho-wis1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10739758", "map_id": "none", "name": "p-S189,T193-MAP2K3, p-S207,T211-MAP2K6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10743960", "map_id": "none", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739826", "map_id": "none", "name": "MAP2K3,MAP2K6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10743948", "map_id": "none", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743936", "map_id": "none", "name": "CDKN2A Gene:H3K27Me3-Nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10743938", "map_id": "none", "name": "CDKN2A Gene:Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10735519", "map_id": "none", "name": "SCF-mediated degradation of Emi1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735512", "map_id": "none", "name": "SCF-associated multiubiquitinated Emi1complexes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9Y709", "map_id": "Q9Y709", "name": "skp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC409.05", "map_id": "SPBC409.05", "name": "skp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09855", "map_id": "Q09855", "name": "pof11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC29E6.01", "map_id": "SPAC29E6.01", "name": "pof11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13790", "map_id": "O13790", "name": "cul1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17G6.12", "map_id": "SPAC17G6.12", "name": "cul1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10729165", "map_id": "none", "name": "Ub", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10735517", "map_id": "none", "name": "Cdc20/Cdh1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13286", "map_id": "O13286", "name": "srw1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC144.13c", "map_id": "SPAC144.13c", "name": "srw1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78972", "map_id": "P78972", "name": "slp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC821.08c", "map_id": "SPAC821.08c", "name": "slp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735506", "map_id": "none", "name": "BTRC:CUL1:SKP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729366", "map_id": "none", "name": "26S proteasome", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94444", "map_id": "O94444", "name": "rpn10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC637.10c", "map_id": "SPAC637.10c", "name": "rpn10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7S2", "map_id": "Q9P7S2", "name": "rpn6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23G3.11", "map_id": "SPAC23G3.11", "name": "rpn6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74445", "map_id": "O74445", "name": "rpt4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1682.16", "map_id": "SPCC1682.16", "name": "rpt4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14126", "map_id": "O14126", "name": "tbp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3A11.12c", "map_id": "SPAC3A11.12c", "name": "tbp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42897", "map_id": "O42897", "name": "rpn3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC119.01", "map_id": "SPBC119.01", "name": "rpn3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94393", "map_id": "O94393", "name": "nas2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2H10.02c", "map_id": "SPAC2H10.02c", "name": "nas2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50524", "map_id": "P50524", "name": "rpn12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16G5.01", "map_id": "SPBC16G5.01", "name": "rpn12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74894", "map_id": "O74894", "name": "rpt3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC576.10c", "map_id": "SPCC576.10c", "name": "rpt3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CU18", "map_id": "P0CU18", "name": "rpn502", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB8E5.02c", "map_id": "SPAPB8E5.02c", "name": "rpn502", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14250", "map_id": "O14250", "name": "PSMA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6G10.04c", "map_id": "SPAC6G10.04c", "name": "PSMA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42931", "map_id": "O42931", "name": "rpt1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16C6.07c", "map_id": "SPBC16C6.07c", "name": "rpt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09841", "map_id": "Q09841", "name": "pup1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23D3.07", "map_id": "SPAC23D3.07", "name": "pup1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CU17", "map_id": "P0CU17", "name": "rpn501", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1420.03", "map_id": "SPAC1420.03", "name": "rpn501", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94517", "map_id": "O94517", "name": "PSMA6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.16", "map_id": "SPBC646.16", "name": "PSMA6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74762", "map_id": "O74762", "name": "rpn2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17D11.07c", "map_id": "SPBC17D11.07c", "name": "rpn2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94579", "map_id": "O94579", "name": "pre8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1442.06", "map_id": "SPCC1442.06", "name": "pre8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36612", "map_id": "P36612", "name": "mts2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4.07c", "map_id": "SPBC4.07c", "name": "mts2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7T8", "map_id": "Q9Y7T8", "name": "pup3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC63.12c", "map_id": "SPCC63.12c", "name": "pup3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43063", "map_id": "O43063", "name": "pre3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4C3.10c", "map_id": "SPBC4C3.10c", "name": "pre3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P30655", "map_id": "P30655", "name": "pts1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4A8.13c", "map_id": "SPAC4A8.13c", "name": "pts1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UQY2", "map_id": "Q9UQY2", "name": "pam1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22F8.06", "map_id": "SPAC22F8.06", "name": "pam1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74440", "map_id": "O74440", "name": "rpn8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1682.10", "map_id": "SPCC1682.10", "name": "rpn8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59770", "map_id": "O59770", "name": "pre10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1795.04c", "map_id": "SPCC1795.04c", "name": "pre10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10335", "map_id": "Q10335", "name": "rpn7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC582.07c", "map_id": "SPBC582.07c", "name": "rpn7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41836", "map_id": "P41836", "name": "let1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC23G7.12c", "map_id": "SPBC23G7.12c", "name": "let1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UT97", "map_id": "Q9UT97", "name": "pup2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC323.02c", "map_id": "SPAC323.02c", "name": "pup2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74867", "map_id": "O74867", "name": "PSMD5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC18.17c", "map_id": "SPCC18.17c", "name": "PSMD5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87048", "map_id": "P87048", "name": "rpn1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP19A11.03c", "map_id": "SPBP19A11.03c", "name": "rpn1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USQ9", "map_id": "Q9USQ9", "name": "PSMB4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC577.10", "map_id": "SPBC577.10", "name": "PSMB4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09720", "map_id": "Q09720", "name": "PSMB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC31A2.04c", "map_id": "SPAC31A2.04c", "name": "PSMB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10329", "map_id": "Q10329", "name": "pre6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC106.16", "map_id": 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"complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC607.05", "map_id": "SPAC607.05", "name": "rpn9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41878", "map_id": "P41878", "name": "rpn11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC31G5.13", "map_id": "SPAC31G5.13", "name": "rpn11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735515", "map_id": "none", "name": "Ubiquitination of Emi1 by SCF-beta-TrCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735510", "map_id": "none", "name": "SCF-beta-TrCP:phospho-Emi1 complexes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10734603", "map_id": "none", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. 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For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734592", "map_id": "P78972", "name": "slp1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734597", "map_id": "O14417", "name": "mad2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC20F10.06", "map_id": "SPBC20F10.06", "name": "mad2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734601", "map_id": "none", "name": "MAD2*CDC20 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14417", "map_id": "O14417", "name": "mad2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735495", "map_id": "none", "name": "Dephosphorylation of phospho-Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735485", "map_id": "O13286", "name": "phospho-srw1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735473", "map_id": "O13286", "name": "srw1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735492", "map_id": "none", "name": "phospho-Cdh1 phosphatase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P7H1", "map_id": "Q9P7H1", "name": "clp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1782.09c", "map_id": "SPAC1782.09c", "name": "clp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734605", "map_id": "none", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734582", "map_id": "O94751", "name": "bub1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC1322.12c", "map_id": "SPCC1322.12c", "name": "bub1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734587", "map_id": "O42860", "name": "bub3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC23H3.08c", "map_id": "SPAC23H3.08c", "name": "bub3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734599", "map_id": "none", "name": "hBUBR1:hBUB3:MAD2*:CDC20 complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94751", "map_id": "O94751", "name": "bub1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42860", "map_id": "O42860", "name": "bub3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737618", "map_id": "none", "name": "Loading of acetylcholine in synaptic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_372511", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_372525", "compartment_display": "clathrin-sculpted acetylcholine transport vesicle lumen", "complex": "false" }, { "id": "species_264643", "map_id": "CHEBI:15355", "name": "AcCho", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10737613", "map_id": "none", "name": "Empty Acetylcholine Synaptic Vesicle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q92356", "map_id": "Q92356", "name": "syb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6G9.11", "map_id": "SPAC6G9.11", "name": "syb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74852", "map_id": "O74852", "name": "SLC18A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC18.02", "map_id": "SPCC18.02", "name": "SLC18A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P17609", "map_id": "P17609", "name": "ypt2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC9E9.07c", "map_id": "SPAC9E9.07c", "name": "ypt2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13876", "map_id": "O13876", "name": "ypt4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1B3.11c", "map_id": "SPAC1B3.11c", "name": "ypt4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10737615", "map_id": "none", "name": "Acetylcholine Loaded Synaptic Vesicle", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737597", "map_id": "O74852", "name": "SLC18A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_373334", "compartment_display": "clathrin-sculpted acetylcholine transport vesicle membrane", "complex": "false" }, { "id": "reaction_10754876", "map_id": "none", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8868399", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8868400", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10754873", "map_id": "none", "name": "OSBPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13944", "map_id": "O13944", "name": "OSBPL3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23H4.01c", "map_id": "SPAC23H4.01c", "name": "OSBPL3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74178", "map_id": "O74178", "name": "kes1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1271.12", "map_id": "SPBC1271.12", "name": "kes1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14340", "map_id": "O14340", "name": "OSBPL7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2F12.05c", "map_id": "SPBC2F12.05c", "name": "OSBPL7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736277", "map_id": "none", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192194", "map_id": "CHEBI:18431", "name": "Cholest-5-ene-3beta,7alpha,27-triol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_29360", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_73473", "map_id": "CHEBI:57945", "name": "NADH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193835", "map_id": "CHEBI:48825", "name": "4CHOL7a,27DONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10736206", "map_id": "O43050", "name": "erg26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC3F6.02c", "map_id": "SPBC3F6.02c", "name": "erg26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736267", "map_id": "none", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193745", "map_id": "CHEBI:63839", "name": "4CHOL7a,12a,24(S)TONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_193707", "map_id": "CHEBI:63830", "name": "5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736185", "map_id": "none", "name": "Homologues of AKR1D1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42888", "map_id": "O42888", "name": "AKR1C4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC8E4.04", "map_id": "SPBC8E4.04", "name": "AKR1C4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13848", "map_id": "O13848", "name": "AKR1C4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10494", "map_id": "Q10494", "name": "AKR1C4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736273", "map_id": "none", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192189", "map_id": "CHEBI:37640", "name": "CHOL7a,24(S)DIOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_193724", "map_id": "CHEBI:63838", "name": "4CHOL7a,24(S)DONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10755031", "map_id": "none", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1806217", "map_id": "CHEBI:17526", "name": "PI4P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_1806234", "map_id": "CHEBI:17526", "name": "PI4P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_8868393", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10755028", "map_id": "none", "name": "Homologues of OSBP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10736211", "map_id": "none", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191980", "map_id": "CHEBI:2290", "name": "5beta-cholestan-7alpha-ol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_192030", "map_id": "CHEBI:28047", "name": "5beta-cholestan-3alpha,7alpha-diol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736196", "map_id": "none", "name": "Homologues of AKR1C4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10736201", "map_id": "none", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192195", "map_id": "CHEBI:28477", "name": "4CHOL7a,12aDONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_192064", "map_id": "CHEBI:2288", "name": "5beta-cholesten-7alpha, 12alpha-diol-3-one", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736269", "map_id": "none", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193760", "map_id": "CHEBI:63829", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_213285", "map_id": "CHEBI:63831", "name": "5beta-cholestan-3alpha,7alpha,24(S)-triol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736199", "map_id": "none", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192087", "map_id": "CHEBI:16496", "name": "5beta-cholestan-3alpha,7alpha,12alpha-triol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736275", "map_id": "none", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193829", "map_id": "CHEBI:48834", "name": "5beta-cholestan-7alpha,12alpha,27-triol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193843", "map_id": "CHEBI:17278", "name": "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736209", "map_id": "none", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_192114", "map_id": "CHEBI:17500", "name": "7 alpha-hydroxycholesterol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_192136", "map_id": "CHEBI:17899", "name": "4CHOL7aOLONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10736283", "map_id": "none", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193830", "map_id": "CHEBI:48778", "name": "5beta-cholestan-7alpha,27-diol-3-one", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193842", "map_id": "CHEBI:28540", "name": "5beta-cholestan-3alpha,7alpha,26-triol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736279", "map_id": "none", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9617026", "map_id": "CHEBI:48833", "name": "4CHOL7a,12a,27TONE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10736271", "map_id": "none", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193728", "map_id": "CHEBI:63834", "name": "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736188", "map_id": "none", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736168", "map_id": "none", "name": "Cholesterol is hydroxylated to 25-hydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176478", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29368", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_192148", "map_id": "CHEBI:42977", "name": "25OH-CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736165", "map_id": "none", "name": "CH25H (Fe2+ cofactor)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9UUH4", "map_id": "Q9UUH4", "name": "erg25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC630.08c", "map_id": "SPAC630.08c", "name": "erg25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736265", "map_id": "none", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736281", "map_id": "none", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736263", "map_id": "none", "name": "ABCB11 transports bile salts from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_193416", "map_id": "none", "name": "bile salts", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17687", "map_id": "CHEBI:17687", "name": "CHEBI:17687", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16525", "map_id": "CHEBI:16525", "name": "CHEBI:16525", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28865", "map_id": "CHEBI:28865", "name": "CHEBI:28865", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:36274", "map_id": "CHEBI:36274", "name": "CHEBI:36274", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_193479", "map_id": "none", "name": "bile salts", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:9407", "map_id": "CHEBI:9407", "name": "CHEBI:9407", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10736260", "map_id": "none", "name": "Homologues of ABCB11", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q02592", "map_id": "Q02592", "name": "hmt1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC737.09c", "map_id": "SPCC737.09c", "name": "hmt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7M7", "map_id": "Q9Y7M7", "name": "mdl1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC9B6.09c", "map_id": "SPBC9B6.09c", "name": "mdl1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36619", "map_id": "P36619", "name": "pmd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC663.03", "map_id": "SPCC663.03", "name": "pmd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756980", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024893", "map_id": "CHEBI:140192", "name": "17R(16)-epoxy-DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024879", "map_id": "CHEBI:140202", "name": "AT-(N)PD1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737736", "map_id": "none", "name": "LTA4H:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_442320", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "O94544", "map_id": "O94544", "name": "lap2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1322.05c", "map_id": "SPCC1322.05c", "name": "lap2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757026", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024873", "map_id": "CHEBI:140225", "name": "16S,17S-epoxy-DHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024886", "map_id": "CHEBI:138655", "name": "(N)PD1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10734197", "map_id": "none", "name": "Hydrolysis of phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426925", "map_id": "CHEBI:16110", "name": "PC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_140356", "map_id": "CHEBI:15843", "name": "ARA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_428981", "map_id": "CHEBI:17504", "name": "LPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10734192", "map_id": "none", "name": "Active PLA2:phosphatidylcholine", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_74016", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_429785", "map_id": "CHEBI:16110", "name": "PC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10756212", "map_id": "none", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734228", "map_id": "none", "name": "PKA tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P36600", "map_id": "P36600", "name": "cgs1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC8C9.03", "map_id": "SPAC8C9.03", "name": "cgs1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40376", "map_id": "P40376", "name": "pka1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC106.10", "map_id": "SPBC106.10", "name": "pka1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_30389", "map_id": "CHEBI:17489", "name": "cAMP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10734230", "map_id": "none", "name": "PKA tetramer:4xcAMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10735214", "map_id": "none", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_947587", "compartment_display": "cytoplasmic side of plasma membrane" }, { "id": "species_10734240", "map_id": "none", "name": "G-protein alpha:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10734135", "map_id": "Q04665", "name": "gpa2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10734214", "map_id": "none", "name": "Phosphorylation of cPLA2 by ERK-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734211", "map_id": "none", "name": "Homologues of PLA2G4A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10733808", "map_id": "P27638", "name": "phospho-spk1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC31G5.09c", "map_id": "SPAC31G5.09c", "name": "spk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734146", "map_id": "none", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_179856", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_114520", "map_id": "CHEBI:16595", "name": "I(1,4,5)P3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_112275", "map_id": "CHEBI:18035", "name": "DAGs", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10734143", "map_id": "none", "name": "Activated PLC beta 1/4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P40977", "map_id": "P40977", "name": "plc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22F8.11", "map_id": "SPAC22F8.11", "name": "plc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734242", "map_id": "none", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734124", "map_id": "P40977", "name": "plc1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10739391", "map_id": "none", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739383", "map_id": "none", "name": "CaMKK:CALM1:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9UU87", "map_id": "Q9UU87", "name": "phospho-ppk34", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1919.01", "map_id": "SPCC1919.01", "name": "phospho-ppk34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P05933", "map_id": "P05933", "name": "cam1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3A12.14", "map_id": "SPAC3A12.14", "name": "cam1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14008", "map_id": "O14008", "name": "cam2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC29A4.05", "map_id": "SPAC29A4.05", "name": "cam2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10739388", "map_id": "none", "name": "p-CaMKK:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734194", "map_id": "none", "name": "Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10734234", "map_id": "none", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734226", "map_id": "P40376", "name": "pka1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734232", "map_id": "none", "name": "cAMP:PKA regulatory subunit", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10738861", "map_id": "none", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_426030", "map_id": "CHEBI:52392", "name": "2AG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_76116", "map_id": "CHEBI:17754", "name": "Glycerol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_422506", "map_id": "CHEBI:15843", "name": "AA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10738858", "map_id": "O94305", "name": "mgl1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPCC5E4.05c", "map_id": "SPCC5E4.05c", "name": "mgl1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749913", "map_id": "none", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5694509", "map_id": "CHEBI:75571", "name": "3AG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10749910", "map_id": "O94437", "name": "ABHD6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPAC22H12.03", "map_id": "SPAC22H12.03", "name": "ABHD6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743111", "map_id": "none", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5357707", "map_id": "CHEBI:30021", "name": "SeMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5357652", "map_id": "CHEBI:9066", "name": "AdoSeMet", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10756166", "map_id": "none", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_8949220", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2889072", "map_id": "CHEBI:29101", "name": "Na+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_8949232", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_2889083", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10756163", "map_id": "P87122", "name": "SLC8B1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPAC3A12.06c", "map_id": "SPAC3A12.06c", "name": "SLC8B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729369", "map_id": "none", "name": "Ubiquitinated Orc1 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729071", "map_id": "P54789", "name": "phospho-orc1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC29A10.15", "map_id": "SPBC29A10.15", "name": "orc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729069", "map_id": "none", "name": "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728907", "map_id": "P54789", "name": "phospho-orc1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10729047", "map_id": "P54789", "name": "phospho-orc1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10729066", "map_id": "none", "name": "SCF (SKP2) complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10728940", "map_id": "none", "name": "Orc1 is phosphorylated by cyclin A/CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728897", "map_id": "none", "name": "pre-replicative complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9Y794", "map_id": "Q9Y794", "name": "orc4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP23A10.13", "map_id": "SPBP23A10.13", "name": "orc4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10067", "map_id": "Q10067", "name": "orc3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3H1.01c", "map_id": "SPAC3H1.01c", "name": "orc3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41389", "map_id": "P41389", "name": "mcm5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1B2.05", "map_id": "SPAC1B2.05", "name": "mcm5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09142", "map_id": "Q09142", "name": "orc2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC685.09", "map_id": "SPBC685.09", "name": "orc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P29458", "map_id": "P29458", "name": "mcm4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC16A11.17", "map_id": "SPCC16A11.17", "name": "mcm4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40382", "map_id": "P40382", "name": "cdt1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC428.18", "map_id": "SPBC428.18", "name": "cdt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P30666", "map_id": "P30666", "name": "mcm3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1682.02c", "map_id": "SPCC1682.02c", "name": "mcm3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P49731", "map_id": "P49731", "name": "mcm6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC211.04c", "map_id": "SPBC211.04c", "name": "mcm6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74796", "map_id": "O74796", "name": "phospho-orc6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2A9.12", "map_id": "SPBC2A9.12", "name": "phospho-orc6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43114", "map_id": "O43114", "name": "orc5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.14c", "map_id": "SPBC646.14c", "name": "orc5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41411", "map_id": "P41411", "name": "cdc18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC14C8.07c", "map_id": "SPBC14C8.07c", "name": "cdc18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40377", "map_id": "P40377", "name": "mcm2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4.04c", "map_id": "SPBC4.04c", "name": "mcm2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P54789", "map_id": "P54789", "name": "orc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O75001", "map_id": "O75001", "name": "mcm7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC25D12.03c", "map_id": "SPBC25D12.03c", "name": "mcm7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10728911", "map_id": "none", "name": "pre-replicative complex (Orc1-minus)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10728937", "map_id": "none", "name": "CCNA:p-T160-CDK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P36630", "map_id": "P36630", "name": "cig2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB2B4.03", "map_id": "SPAPB2B4.03", "name": "cig2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P10815", "map_id": "P10815", "name": "cdc13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC582.03", "map_id": "SPBC582.03", "name": "cdc13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P04551", "map_id": "P04551", "name": "phospho-cdc2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC11B10.09", "map_id": "SPBC11B10.09", "name": "phospho-cdc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P25009", "map_id": "P25009", "name": "puc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19F5.01c", "map_id": "SPBC19F5.01c", "name": "puc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729409", "map_id": "none", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728714", "map_id": "P41411", "name": "cdc18", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10729384", "map_id": "P41411", "name": "phospho-cdc18", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10729406", "map_id": "none", "name": "CCNA:p-T160-CDK2,CCNE:p-T160-CDK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10729419", "map_id": "none", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729417", "map_id": "none", "name": "ubiquitinated Cdc6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10729421", "map_id": "none", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728861", "map_id": "none", "name": "MCM2-7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10728857", "map_id": "P41389", "name": "mcm5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728852", "map_id": "P30666", "name": "mcm3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728828", "map_id": "P40377", "name": "mcm2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728845", "map_id": "none", "name": "MCM4:MCM6:MCM7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10729073", "map_id": "none", "name": "Ubiquitinated Orc1 enters the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10729413", "map_id": "none", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729411", "map_id": "P41411", "name": "phospho-cdc18", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736391", "map_id": "none", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73524", "map_id": "CHEBI:17621", "name": "FMN", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29386", "map_id": "CHEBI:16238", "name": "FAD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736388", "map_id": "O74841", "name": "FLAD1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC1235.04c", "map_id": "SPCC1235.04c", "name": "FLAD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736411", "map_id": "none", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196931", "map_id": "CHEBI:17015", "name": "RIB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736408", "map_id": "none", "name": "RFK:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74866", "map_id": "O74866", "name": "fmn1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC18.16c", "map_id": "SPCC18.16c", "name": "fmn1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736401", "map_id": "none", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736398", "map_id": "none", "name": "2xENPP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O94323", "map_id": "O94323", "name": "ENPP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC725.05c", "map_id": "SPBC725.05c", "name": "ENPP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738598", "map_id": "none", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_74112", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10738589", "map_id": "Q9HDW7", "name": "pmc1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPAPB2B4.04c", "map_id": "SPAPB2B4.04c", "name": "pmc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746051", "map_id": "none", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10738595", "map_id": "Q9HDW7", "name": "pmc1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10738606", "map_id": "none", "name": "Homologues of NOS1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9US28", "map_id": "Q9US28", "name": "NOS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC12C2.03c", "map_id": "SPBC12C2.03c", "name": "NOS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09744", "map_id": "Q09744", "name": "NOS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36587", "map_id": "P36587", "name": "ccr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29A10.01", "map_id": "SPBC29A10.01", "name": "ccr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746049", "map_id": "none", "name": "ATP2B4:NOS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9HDW7", "map_id": "Q9HDW7", "name": "pmc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745982", "map_id": "none", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10746751", "map_id": "none", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746748", "map_id": "O74304", "name": "phospho-win1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10739639", "map_id": "none", "name": "TRAF6 is K63 poly-ubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739630", "map_id": "none", "name": "hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13924", "map_id": "O13924", "name": "phospho-hrk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23C4.03", "map_id": "SPAC23C4.03", "name": "phospho-hrk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74983", "map_id": "O74983", "name": "spm2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC338.05c", "map_id": "SPCC338.05c", "name": "spm2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13685", "map_id": "O13685", "name": "ubc13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC11E3.04c", "map_id": "SPAC11E3.04c", "name": "ubc13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10739636", "map_id": "none", "name": "hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746745", "map_id": "none", "name": "26Sproteasome degrades K48polyUb-NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746743", "map_id": "O74304", "name": "win1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10735267", "map_id": "none", "name": "Phosphorylated MAPKs phosphorylate ATF-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10735231", "map_id": "none", "name": "Homologues of ATF2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P52890", "map_id": "P52890", "name": "atf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29B5.01", "map_id": "SPBC29B5.01", "name": "atf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78962", "map_id": "P78962", "name": "atf21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2F12.09c", "map_id": "SPBC2F12.09c", "name": "atf21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09771", "map_id": "Q09771", "name": "atf31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22F3.02", "map_id": "SPAC22F3.02", "name": "atf31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735245", "map_id": "none", "name": "Homologues of p-T69,T71-ATF2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10735264", "map_id": "none", "name": "Activated MAPK kinases ERK1/2, JNK, p38", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q09892", "map_id": "Q09892", "name": "phospho-sty1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P27638", "map_id": "P27638", "name": "spk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q92398", "map_id": "Q92398", "name": "spm1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC119.08", "map_id": "SPBC119.08", "name": "spm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739950", "map_id": "none", "name": "Pellino ubiquitinates IRAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739939", "map_id": "none", "name": "hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10739947", "map_id": "none", "name": "K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10736765", "map_id": "none", "name": "ERKs are inactivated by protein phosphatase 2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10736632", "map_id": "none", "name": "p-T,Y MAPK dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10736739", "map_id": "none", "name": "MAPK3/MAPK1/MAPK7 dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10736762", "map_id": "none", "name": "PP2A-ABdeltaC complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q10428", "map_id": "Q10428", "name": "par1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC188.02", "map_id": "SPCC188.02", "name": "par1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UT08", "map_id": "Q9UT08", "name": "paa1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAP8A3.09c", "map_id": "SPAP8A3.09c", "name": "paa1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P23636", "map_id": "P23636", "name": "ppa2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16H5.07c", "map_id": "SPBC16H5.07c", "name": "ppa2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736635", "map_id": "none", "name": "ERK1/2 phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10736617", "map_id": "Q12706", "name": "psk1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPCC4G3.08", "map_id": "SPCC4G3.08", "name": "psk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10736623", "map_id": "Q12706", "name": "phospho-psk1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10737238", "map_id": "none", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10737231", "map_id": "O13453", "name": "pmp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC1685.01", "map_id": "SPBC1685.01", "name": "pmp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736626", "map_id": "none", "name": "p38MAPK phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10735252", "map_id": "Q09892", "name": "phospho-sty1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10739512", "map_id": "none", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449221", "map_id": "CHEBI:16091", "name": "DCHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10739509", "map_id": "Q9Y7T6", "name": "sec59", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPCC63.10c", "map_id": "SPCC63.10c", "name": "sec59", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744801", "map_id": "none", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_4419981", "map_id": "CHEBI:67132", "name": "pPNOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10744798", "map_id": "O14264", "name": "SRD5A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC7D4.09c", "map_id": "SPAC7D4.09c", "name": "SRD5A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739528", "map_id": "none", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449744", "map_id": "CHEBI:15750", "name": "DOLDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10739525", "map_id": "O59747", "name": "pdf1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC530.12c", "map_id": "SPBC530.12c", "name": "pdf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736144", "map_id": "none", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191403", "map_id": "CHEBI:15899", "name": "MVA5PP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191362", "map_id": "CHEBI:16584", "name": "IPPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736141", "map_id": "none", "name": "MVD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13963", "map_id": "O13963", "name": "mvd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC24C9.03", "map_id": "SPAC24C9.03", "name": "mvd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744793", "map_id": "none", "name": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_4419987", "map_id": "CHEBI:17407", "name": "E,E-FPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_4419982", "map_id": "CHEBI:37531", "name": "pPPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10744790", "map_id": "none", "name": "DHDDS:NUS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O14171", "map_id": "O14171", "name": "DHDDS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4D7.04c", "map_id": "SPAC4D7.04c", "name": "DHDDS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7K8", "map_id": "Q9Y7K8", "name": "nus1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2A9.06c", "map_id": "SPBC2A9.06c", "name": "nus1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739410", "map_id": "none", "name": "Phosphorylation of L1 by ERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738464", "map_id": "none", "name": "L1:AP-2 Clathrin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20592", "compartment_display": "clathrin-coated endocytic vesicle", "complex": "true" }, { "id": "O43125", "map_id": "O43125", "name": "csh3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC119.05c", "map_id": "SPBC119.05c", "name": "csh3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10739408", "map_id": "none", "name": "pL1 (S1204, 1248):ERK2:clathrin-dynamin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17940", "compartment_display": "endosome", "complex": "true" }, { "id": "reaction_10733813", "map_id": "none", "name": "MAP2K2 phosphorylates MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733780", "map_id": "none", "name": "p-S,T-MAP2K2:MAPK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10733810", "map_id": "none", "name": "p-S,T-MAP2K2:p-T,Y-MAPK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10738466", "map_id": "none", "name": "Transport of L1 into endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17940", "compartment_display": "endosome" }, { "id": "reaction_10733803", "map_id": "none", "name": "MAP2K1 phosphorylates MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733770", "map_id": "none", "name": "p-2S-MAP2K1:MAPK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10733794", "map_id": "none", "name": "p-T,Y-MAPK3:p-2S-MAP2K1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10733799", "map_id": "P10506", "name": "phospho-byr1", "type": "inhibitor", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10740265", "map_id": "none", "name": "Formation of clathrin coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10735803", "map_id": "O43125", "name": "csh3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10740252", "map_id": "none", "name": "L1:clathrin-coated vesicle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10740262", "map_id": "none", "name": "Dynamin-1/2/3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P87320", "map_id": "P87320", "name": "msp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1718.06", "map_id": "SPBC1718.06", "name": "msp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09748", "map_id": "Q09748", "name": "dnm1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC12C2.08", "map_id": "SPBC12C2.08", "name": "dnm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9URZ5", "map_id": "Q9URZ5", "name": "vps1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC767.01c", "map_id": "SPAC767.01c", "name": "vps1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742224", "map_id": "none", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614518", "map_id": "CHEBI:17482", "name": "L-Cystathionine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29382", "map_id": "CHEBI:16134", "name": "NH3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_936714", "map_id": "CHEBI:30831", "name": "2OBUTA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111707", "map_id": "CHEBI:35235", "name": "L-Cys", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10742218", "map_id": "none", "name": "PXLP-K212-CTH tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42851", "map_id": "O42851", "name": "PXLP-K212-CTH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23A1.14c", "map_id": "SPAC23A1.14c", "name": "PXLP-K212-CTH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744044", "map_id": "none", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744037", "map_id": "none", "name": "CCS:Zn2+:2xCu1+:SOD1:Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P28758", "map_id": "P28758", "name": "sod1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC821.10c", "map_id": "SPAC821.10c", "name": "sod1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10357", "map_id": "Q10357", "name": "ccs1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22E12.04", "map_id": "SPAC22E12.04", "name": "ccs1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:49552", "map_id": "CHEBI:49552", "name": "CHEBI:49552", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744041", "map_id": "none", "name": "CCS:Zn2+:Cu1+ dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10744022", "map_id": "none", "name": "2xHC-SOD1:Zn2+:Cu2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_437295", "map_id": "CHEBI:29036", "name": "Cu2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10744457", "map_id": "none", "name": "PRDX5 reduces peroxynitrite to nitrite using TXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1222481", "map_id": "CHEBI:25941", "name": "Peroxynitrite", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1222379", "map_id": "CHEBI:16301", "name": "Nitrite", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10744099", "map_id": "O14313", "name": "pmp20", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC330.06c", "map_id": "SPCC330.06c", "name": "pmp20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744104", "map_id": "none", "name": "PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29408", "map_id": "CHEBI:16240", "name": "H2O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10744101", "map_id": "none", "name": "PRDX1,2,5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14313", "map_id": "O14313", "name": "pmp20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74887", "map_id": "O74887", "name": "tpx1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC576.03c", "map_id": "SPCC576.03c", "name": "tpx1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744454", "map_id": "none", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744035", "map_id": "none", "name": "SOD1:Zn2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10744450", "map_id": "none", "name": "CCS:Zn2+:2xCu1+ dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10744452", "map_id": "none", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756210", "map_id": "none", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10744025", "map_id": "none", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1222424", "map_id": "CHEBI:18421", "name": "O2.-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10744083", "map_id": "none", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_3341308", "map_id": "CHEBI:18421", "name": "O2-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10734930", "map_id": "none", "name": "Cytochrome c (oxidised)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P00046", "map_id": "P00046", "name": "cyc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC191.07", "map_id": "SPCC191.07", "name": "cyc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:38574", "map_id": "CHEBI:38574", "name": "CHEBI:38574", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_189461", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10734928", "map_id": "none", "name": "Cytochrome c (reduced)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "CHEBI:38573", "map_id": "CHEBI:38573", "name": "CHEBI:38573", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744079", "map_id": "none", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113600", "map_id": "CHEBI:16474", "name": "NADPH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_1655882", "map_id": "CHEBI:17858", "name": "GSSG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113529", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113563", "map_id": "CHEBI:18009", "name": "NADP+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_1655887", "map_id": "CHEBI:16856", "name": "GSH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10744076", "map_id": "none", "name": "GSR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10744015", "map_id": "none", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_3299686", "map_id": "CHEBI:18421", "name": "O2.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_351626", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_351629", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_352327", "map_id": "CHEBI:15379", "name": "O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10744012", "map_id": "none", "name": "SOD3 tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10744004", "map_id": "none", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_3299683", "map_id": "CHEBI:18421", "name": "O2.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113533", "map_id": "CHEBI:15379", "name": "O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_1614617", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10744001", "map_id": "none", "name": "SOD2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9UQX0", "map_id": "Q9UQX0", "name": "sod2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1486.01", "map_id": "SPAC1486.01", "name": "sod2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_113527", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10733436", "map_id": "none", "name": "2 H2O2 => O2 + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_113575", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_141343", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_113535", "map_id": "CHEBI:15379", "name": "O2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10733433", "map_id": "none", "name": "CAT tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "species_189444", "map_id": "CHEBI:17627", "name": "heme", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P55306", "map_id": "P55306", "name": "cta1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC757.07c", "map_id": "SPCC757.07c", "name": "cta1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744568", "map_id": "none", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_163953", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189481", "map_id": "CHEBI:16240", "name": "H2O2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10744565", "map_id": "none", "name": "SOD1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "reaction_10745062", "map_id": "none", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_10745060", "map_id": "none", "name": "SOD3 tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10746853", "map_id": "none", "name": "p-T,Y MAPKs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741495", "map_id": "none", "name": "p-T,Y MAPKs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10744304", "map_id": "none", "name": "p-T,Y MAPK dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757290", "map_id": "none", "name": "p-T,Y MAPK dimers translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10739876", "map_id": "none", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739853", "map_id": "P47979", "name": "zfs1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC1718.07c", "map_id": "SPBC1718.07c", "name": "zfs1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_450523", "map_id": "none", "name": "mRNA Transcript Targeted by BRF1", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739855", "map_id": "none", "name": "BRF1:mRNA Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P47979", "map_id": "P47979", "name": "zfs1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739870", "map_id": "none", "name": "Protein Kinase B/Akt phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739867", "map_id": "none", "name": "Phosphorylated BRF1 (Ser92, Ser203):mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10736495", "map_id": "none", "name": "Homologues of p-T308,S473-AKT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10738965", "map_id": "none", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_188972", "map_id": "CHEBI:17996", "name": "Cl-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_352022", "map_id": "CHEBI:17996", "name": "Cl-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10738962", "map_id": "none", "name": "SLC26 chloride transporters", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O59782", "map_id": "O59782", "name": "SLC26A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC320.05", "map_id": "SPCC320.05", "name": "SLC26A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738848", "map_id": "none", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_425978", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171043", "compartment_display": "early endosome lumen", "complex": "false" }, { "id": "species_83910", "map_id": "CHEBI:29101", "name": "Na+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_425971", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171043", "compartment_display": "early endosome lumen", "complex": "false" }, { "id": "species_10738845", "map_id": "none", "name": "SLC9A6,7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "O13726", "map_id": "O13726", "name": "SLC9A9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC15A10.06", "map_id": "SPAC15A10.06", "name": "SLC9A9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738839", "map_id": "none", "name": "SLC9A9 exchanges Na+ for H+ across the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_425999", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_173031", "compartment_display": "late endosome lumen", "complex": "false" }, { "id": "species_425977", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_173031", "compartment_display": "late endosome lumen", "complex": "false" }, { "id": "species_10738836", "map_id": "O13726", "name": "SLC9A9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "reaction_10746330", "map_id": "none", "name": "SLC26A4 transports I- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_209785", "map_id": "CHEBI:16382", "name": "I-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_209818", "map_id": "CHEBI:16382", "name": "I-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10746327", "map_id": "O59782", "name": "SLC26A4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10738878", "map_id": "none", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_74113", "map_id": "CHEBI:29101", "name": "Na+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10738875", "map_id": "O60146", "name": "SLC12A3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPBC18H10.16", "map_id": "SPBC18H10.16", "name": "SLC12A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10754356", "map_id": "none", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2162252", "map_id": "CHEBI:16680", "name": "AdoHcy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162265", "map_id": "CHEBI:15414", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10754353", "map_id": "Q10442", "name": "SLC25A26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPAC12B10.09", "map_id": "SPAC12B10.09", "name": "SLC25A26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738984", "map_id": "none", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_427984", "map_id": "none", "name": "Histidine/di-peptides", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "CHEBI:90799", "map_id": "CHEBI:90799", "name": "CHEBI:90799", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:32513", "map_id": "CHEBI:32513", "name": "CHEBI:32513", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_428040", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_428003", "map_id": "none", "name": "Histidine/di-peptides", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:46761", "map_id": "CHEBI:46761", "name": "CHEBI:46761", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10738979", "map_id": "Q9P380", "name": "ptr2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "SPBC13A2.04c", "map_id": "SPBC13A2.04c", "name": "ptr2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738956", "map_id": "none", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_427648", "map_id": "CHEBI:16189", "name": "SO4(2-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_174375", "map_id": "CHEBI:16189", "name": "SO4(2-)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10738953", "map_id": "none", "name": "SLC26A1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10755472", "map_id": "none", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_113552", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10755469", "map_id": "none", "name": "SLC25A18,A22", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q9P3T7", "map_id": "Q9P3T7", "name": "SLC25A18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC328.09", "map_id": "SPAC328.09", "name": "SLC25A18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755488", "map_id": "none", "name": "SLC26A11 transports SO4(2-) from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10755485", "map_id": "Q9URY8", "name": "SLC26A11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPAC869.05c", "map_id": "SPAC869.05c", "name": "SLC26A11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738819", "map_id": "none", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_425815", "map_id": "CHEBI:49713", "name": "Li+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_425810", "map_id": "CHEBI:49713", "name": "Li+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10738816", "map_id": "P87122", "name": "SLC24A6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10738974", "map_id": "none", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_111627", "map_id": "CHEBI:17544", "name": "HCO3-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_425425", "map_id": "CHEBI:17544", "name": "HCO3-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10738971", "map_id": "none", "name": "SLC26A3,6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10738873", "map_id": "none", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_29804", "map_id": "CHEBI:29103", "name": "K+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10738870", "map_id": "none", "name": "SLC12A1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O60146", "map_id": "O60146", "name": "SLC12A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738853", "map_id": "none", "name": "Na+/H+ exchanger transport (at trans-golgi membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_425969", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_425958", "map_id": "CHEBI:29101", "name": "Na+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10738850", "map_id": "O13726", "name": "SLC9A7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10753176", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6809774", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_422529", "map_id": "CHEBI:16500", "name": "PI5P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10753168", "map_id": "none", "name": "MTMR2:SBF1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O13819", "map_id": "O13819", "name": "MTMR3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC19A8.03", "map_id": "SPAC19A8.03", "name": "MTMR3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753572", "map_id": "none", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_109276", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_2239407", "map_id": "CHEBI:60479", "name": "lysophosphatidylcholine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_6814794", "map_id": "CHEBI:18132", "name": "ChoP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_6814795", "map_id": "CHEBI:17408", "name": "MAG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10753569", "map_id": "O94323", "name": "ENPP6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10753131", "map_id": "none", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10753127", "map_id": "O13819", "name": "MTMR9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10753125", "map_id": "O13819", "name": "MTMR8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10753129", "map_id": "none", "name": "MTMR8:MTMR9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742441", "map_id": "none", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1806276", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_426658", "map_id": "CHEBI:16749", "name": "PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10742438", "map_id": "none", "name": "MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O43001", "map_id": "O43001", "name": "syj1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2G2.02", "map_id": "SPBC2G2.02", "name": "syj1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753468", "map_id": "none", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_6810408", "map_id": "CHEBI:16500", "name": "PI5P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_6810412", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10753465", "map_id": "none", "name": "PIP4K2 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O13853", "map_id": "O13853", "name": "its3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC19G12.14", "map_id": "SPAC19G12.14", "name": "its3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742467", "map_id": "none", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426639", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10742464", "map_id": "O60162", "name": "SACM1L", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC19F5.03", "map_id": "SPBC19F5.03", "name": "SACM1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753148", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1806224", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1806240", "map_id": "CHEBI:16500", "name": "PI5P", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10753145", "map_id": "none", "name": "MTMR6:MTMR9,MTMR8:MTMR9", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742498", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1524146", "map_id": "CHEBI:16749", "name": "PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10742495", "map_id": "none", "name": "PI4KA/2A/2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UT42", "map_id": "Q9UT42", "name": "lsb6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC343.19", "map_id": "SPAC343.19", "name": "lsb6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USR3", "map_id": "Q9USR3", "name": "stt4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC577.06c", "map_id": "SPBC577.06c", "name": "stt4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742443", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_1806195", "map_id": "CHEBI:16749", "name": "PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_1806198", "map_id": "CHEBI:17283", "name": "PI3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_10742410", "map_id": "none", "name": "PIK3C3:Mn2+:PIK3R4:Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42900", "map_id": "O42900", "name": "ppk19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC119.07", "map_id": "SPBC119.07", "name": "ppk19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50520", "map_id": "P50520", "name": "vps34", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC458.05", "map_id": "SPAC458.05", "name": "vps34", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742425", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1806159", "map_id": "CHEBI:17283", "name": "PI3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10753515", "map_id": "none", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6814253", "map_id": "CHEBI:58168", "name": "LysoPtdCho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1498750", "map_id": "CHEBI:16870", "name": "GPCho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1524021", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10753512", "map_id": "Q9USJ4", "name": "nte1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPCC4B3.04c", "map_id": "SPCC4B3.04c", "name": "nte1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753151", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10742449", "map_id": "none", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_392417", "map_id": "CHEBI:17526", "name": "PI4P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10742313", "map_id": "O13853", "name": "its3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742382", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10742379", "map_id": "none", "name": "PI4KA/2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742353", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10742348", "map_id": "Q9UT42", "name": "lsb6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742476", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_1806200", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "species_1806199", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "species_10742451", "map_id": "none", "name": "MTM1,MTMR2,MTMR4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10753164", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTM1:MTMR12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_10753155", "map_id": "none", "name": "MTM1:MTMR12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742473", "map_id": "none", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10742423", "map_id": "none", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_202247", "map_id": "CHEBI:16152", "name": "PI(3,4)P2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10742418", "map_id": "Q9USQ6", "name": "syj2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC577.13", "map_id": "SPBC577.13", "name": "syj2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753157", "map_id": "none", "name": "MTMR12 binds MTM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10753153", "map_id": "O13819", "name": "MTMR12", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10742358", "map_id": "O13819", "name": "MTM1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742462", "map_id": "none", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10742459", "map_id": "O60162", "name": "SACM1L", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10742488", "map_id": "none", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10742486", "map_id": "Q10366", "name": "pik1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC22E12.16c", "map_id": "SPAC22E12.16c", "name": "pik1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10742399", "map_id": "none", "name": "ARF1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P36579", "map_id": "P36579", "name": "arf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4F6.18c", "map_id": "SPBC4F6.18c", "name": "arf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:15996", "map_id": "CHEBI:15996", "name": "CHEBI:15996", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10742401", "map_id": "none", "name": "ARF1/3:GTP:PI4KB", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q10366", "map_id": "Q10366", "name": "pik1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742508", "map_id": "none", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1806230", "map_id": "CHEBI:16152", "name": "PI(3,4)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10742503", "map_id": "O94526", "name": "ptn1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "SPBC609.02", "map_id": "SPBC609.02", "name": "phospho-ptn1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742454", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_1806205", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "species_1806259", "map_id": "CHEBI:16500", "name": "PI5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "reaction_10742501", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10753170", "map_id": "none", "name": "SBF1 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742360", "map_id": "O13819", "name": "MTMR2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10753166", "map_id": "O13819", "name": "SBF1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10742484", "map_id": "none", "name": "PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10736691", "map_id": "O94526", "name": "ptn1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742481", "map_id": "none", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10742478", "map_id": "none", "name": "PIP4K2/5K1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742430", "map_id": "none", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10742387", "map_id": "O43001", "name": "syj1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742320", "map_id": "none", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10742404", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10736694", "map_id": "none", "name": "PTEN dephosphorylates PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10742446", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "species_1806289", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_1806212", "map_id": "CHEBI:16500", "name": "PI5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_172574", "compartment_display": "late endosome membrane", "complex": "false" }, { "id": "species_10742366", "map_id": "none", "name": "MTM1,MTMR2,MTMR4,MTMR7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742392", "map_id": "none", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10742372", "map_id": "none", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10742413", "map_id": "none", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "reaction_10742369", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_172574", "compartment_display": "late endosome membrane" }, { "id": "reaction_10753143", "map_id": "none", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742436", "map_id": "O13819", "name": "MTMR6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10753141", "map_id": "none", "name": "MTMR6:MTMR9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10753161", "map_id": "none", "name": "MTMR12 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10753159", "map_id": "none", "name": "MTMR2:MTMR12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742493", "map_id": "none", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10742490", "map_id": "none", "name": "SYNJ/INPP5(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9USQ6", "map_id": "Q9USQ6", "name": "syj2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742343", "map_id": "none", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10742340", "map_id": "none", "name": "PIP4K2 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10753173", "map_id": "none", "name": "PI3P is dephosphorylated to PI by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5676030", "map_id": "CHEBI:26034", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10742470", "map_id": "none", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10742427", "map_id": "none", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_171062", "compartment_display": "early endosome membrane" }, { "id": "species_1806180", "map_id": "CHEBI:17526", "name": "PI4P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "false" }, { "id": "reaction_10732994", "map_id": "none", "name": "Formation of AT-AC C complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10732990", "map_id": "none", "name": "ATAC B Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O59670", "map_id": "O59670", "name": "SF3B6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29A3.07c", "map_id": "SPBC29A3.07c", "name": "SF3B6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10163", "map_id": "Q10163", "name": "smb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26A3.08", "map_id": "SPAC26A3.08", "name": "smb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94424", "map_id": "O94424", "name": "tfg2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1198.13c", "map_id": "SPBC1198.13c", "name": "tfg2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USZ3", "map_id": "Q9USZ3", "name": "sme1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC11G11.06c", "map_id": "SPBC11G11.06c", "name": "sme1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UTT2", "map_id": "Q9UTT2", "name": "prp12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPJ698.03c", "map_id": "SPAPJ698.03c", "name": "prp12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUI3", "map_id": "Q9UUI3", "name": "sap145", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22F8.10c", "map_id": "SPAC22F8.10c", "name": "sap145", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7T7", "map_id": "Q9Y7T7", "name": "prp28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC63.11", "map_id": "SPCC63.11", "name": "prp28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42661", "map_id": "O42661", "name": "smd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27D7.07c", "map_id": "SPAC27D7.07c", "name": "smd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59734", "map_id": "O59734", "name": "smf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3E7.14", "map_id": "SPBC3E7.14", "name": "smf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74690", "map_id": "O74690", "name": "snu13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC607.03c", "map_id": "SPAC607.03c", "name": "snu13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14187", "map_id": "O14187", "name": "spp42", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4F8.12c", "map_id": "SPAC4F8.12c", "name": "spp42", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10178", "map_id": "Q10178", "name": "prp10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27F1.09c", "map_id": "SPAC27F1.09c", "name": "prp10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94620", "map_id": "O94620", "name": "cwf17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1289.11", "map_id": "SPBC1289.11", "name": "cwf17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUC6", "map_id": "Q9UUC6", "name": "smd3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19C2.14", "map_id": "SPBC19C2.14", "name": "smd3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87215", "map_id": "P87215", "name": "dim1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC16A11.05c", "map_id": "SPCC16A11.05c", "name": "dim1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94416", "map_id": "O94416", "name": "tfg1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1620.09c", "map_id": "SPCC1620.09c", "name": "tfg1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14036", "map_id": "O14036", "name": "smd2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2C4.03c", "map_id": "SPAC2C4.03c", "name": "smd2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UT24", "map_id": "Q9UT24", "name": "brr2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC9.03c", "map_id": "SPAC9.03c", "name": "brr2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94316", "map_id": "O94316", "name": "cwf10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC215.12", "map_id": "SPBC215.12", "name": "cwf10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7R6", "map_id": "Q9P7R6", "name": "SF3B5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC211.05", "map_id": "SPBC211.05", "name": "SF3B5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12381", "map_id": "Q12381", "name": "prp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC6B1.07", "map_id": "SPBC6B1.07", "name": "prp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74966", "map_id": "O74966", "name": "smg1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4B4.05", "map_id": "SPBC4B4.05", "name": "smg1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10732982", "map_id": "none", "name": "U4 ATAC snRNP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10732992", "map_id": "none", "name": "ATAC C Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10732996", "map_id": "none", "name": "ATAC spliceosome mediated Lariat formation,5' splice site cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10729563", "map_id": "none", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729559", "map_id": "none", "name": "CCNE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729541", "map_id": "P04551", "name": "cdc2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729561", "map_id": "none", "name": "CCNE:CDK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10735839", "map_id": "none", "name": "CAK-mediated phosphorylation of Cyclin E:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729567", "map_id": "none", "name": "CCNE:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729404", "map_id": "none", "name": "Cyclin E:p-T160-CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10732457", "map_id": "none", "name": "CAK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10729580", "map_id": "none", "name": "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729572", "map_id": "none", "name": "Cyclin E:p-CDK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729577", "map_id": "P06652", "name": "cdc25", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC24H6.05", "map_id": "SPAC24H6.05", "name": "cdc25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734745", "map_id": "none", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "reaction_10747656", "map_id": "none", "name": "CHEK1 phosphorylates RAD51", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747651", "map_id": "P36601", "name": "rhp51", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC644.14c", "map_id": "SPAC644.14c", "name": "rhp51", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747654", "map_id": "P36601", "name": "phospho-rhp51", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10729605", "map_id": "none", "name": "Homologues of p-S317,S345-CHEK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O13945", "map_id": "O13945", "name": "phospho-ppk9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23H4.02", "map_id": "SPAC23H4.02", "name": "phospho-ppk9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74536", "map_id": "O74536", "name": "phospho-ssp2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC74.03c", "map_id": "SPCC74.03c", "name": "phospho-ssp2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10747710", "map_id": "none", "name": "MRN and RBBP8 resect DNA DSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747703", "map_id": "none", "name": "DNA DSB:MRN:RBBP8", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q09683", "map_id": "Q09683", "name": "rad32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13C5.07", "map_id": "SPAC13C5.07", "name": "rad32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UTJ8", "map_id": "Q9UTJ8", "name": "rad50", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1556.01c", "map_id": "SPAC1556.01c", "name": "rad50", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43070", "map_id": "O43070", "name": "nbs1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC6B1.09c", "map_id": "SPBC6B1.09c", "name": "nbs1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747707", "map_id": "none", "name": "Microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30555", "map_id": "CHEBI:16516", "name": "dNTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10733424", "map_id": "none", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733420", "map_id": "P36592", "name": "rad22", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC30D11.10", "map_id": "SPAC30D11.10", "name": "rad22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733422", "map_id": "none", "name": "RAD52 heptamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P36592", "map_id": "P36592", "name": "rad22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10747593", "map_id": "none", "name": "ATM phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747581", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S327,T847-RBBP8:p-S1981,Ac-K3016-ATM:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q10325", "map_id": "Q10325", "name": "mst2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17G8.13c", "map_id": "SPAC17G8.13c", "name": "mst2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74630", "map_id": "O74630", "name": "tel1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC23B6.03c", "map_id": "SPCC23B6.03c", "name": "tel1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747590", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S327,T847,T859-RBBP8:p-S1981,Ac-K3016-ATM:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747723", "map_id": "none", "name": "FEN1 cleaves displaced ssDNA flaps during MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747716", "map_id": "none", "name": "Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:FEN1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P39750", "map_id": "P39750", "name": "rad2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3G6.06c", "map_id": "SPAC3G6.06c", "name": "rad2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747720", "map_id": "none", "name": "Extended microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729528", "map_id": "P39750", "name": "rad2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_68454", "map_id": "none", "name": "Flap", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10747676", "map_id": "none", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747661", "map_id": "Q9C103", "name": "eme1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAPB1E7.06c", "map_id": "SPAPB1E7.06c", "name": "eme1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747668", "map_id": "P87231", "name": "mus81", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPCC4G3.05c", "map_id": "SPCC4G3.05c", "name": "mus81", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747674", "map_id": "none", "name": "MUS81:EME1, (MUS81:EME2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9C103", "map_id": "Q9C103", "name": "eme1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87231", "map_id": "P87231", "name": "mus81", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10747584", "map_id": "none", "name": "CDK2 phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747575", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756974", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9023708", "map_id": "CHEBI:138563", "name": "5S,6S-epoxy-18(R)-HEPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9023712", "map_id": "CHEBI:81559", "name": "18(R)-RvE1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10756059", "map_id": "none", "name": "SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10756041", "map_id": "Q9UTL9", "name": "SHPRH", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC144.05", "map_id": "SPAC144.05", "name": "SHPRH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746403", "map_id": "none", "name": "RAD18:UBE2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P23566", "map_id": "P23566", "name": "rhp6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC18B11.07c", "map_id": "SPAC18B11.07c", "name": "rhp6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74747", "map_id": "O74747", "name": "rhp18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1734.06", "map_id": "SPBC1734.06", "name": "rhp18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733964", "map_id": "none", "name": "MonoUb:K164-PCNA homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q03392", "map_id": "Q03392", "name": "pcn1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16D10.09", "map_id": "SPBC16D10.09", "name": "pcn1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756047", "map_id": "none", "name": "Ub:UBE2N:UBE2V2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10756049", "map_id": "none", "name": "SHPRH:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9UTL9", "map_id": "Q9UTL9", "name": "SHPRH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756057", "map_id": "none", "name": "SHPRH polyubiquitinates monoubiquitinated PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10756054", "map_id": "none", "name": "K63polyUb-K164-PCNA homotrimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10747373", "map_id": "none", "name": "UBE2N:UBE2V2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756390", "map_id": "none", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10756378", "map_id": "none", "name": "PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "O60065", "map_id": "O60065", "name": "pex14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC13G1.03c", "map_id": "SPBC13G1.03c", "name": "pex14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94325", "map_id": "O94325", "name": "phospho-pex5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC725.07", "map_id": "SPBC725.07", "name": "phospho-pex5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8TFH8", "map_id": "Q8TFH8", "name": "pex12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB17E12.03", "map_id": "SPAPB17E12.03", "name": "pex12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUF0", "map_id": "Q9UUF0", "name": "pas4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17A3.10", "map_id": "SPBC17A3.10", "name": "pas4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UTN8", "map_id": "Q9UTN8", "name": "ubc14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1250.03", "map_id": "SPAC1250.03", "name": "ubc14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P46595", "map_id": "P46595", "name": "ubc4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC119.02", "map_id": "SPBC119.02", "name": "ubc4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14136", "map_id": "O14136", "name": "pex13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3C7.10", "map_id": "SPAC3C7.10", "name": "pex13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756387", "map_id": "none", "name": "PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "species_10741537", "map_id": "none", "name": "UBE2D1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756380", "map_id": "none", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10756372", "map_id": "none", "name": "PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "species_10756376", "map_id": "none", "name": "Ub:UBE2D1,2,3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10733705", "map_id": "none", "name": "Recognition and Binding of Core Promoter Elements by TFIID", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_109627", "map_id": "none", "name": "DNA containing RNA Polymerase II promoter", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10732699", "map_id": "none", "name": "TFIID", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O13722", "map_id": "O13722", "name": "taf12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC15A10.02", "map_id": "SPAC15A10.02", "name": "taf12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09813", "map_id": "Q09813", "name": "TAF1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2G11.14", "map_id": "SPAC2G11.14", "name": "TAF1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74462", "map_id": "O74462", "name": "taf6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC16C4.18c", "map_id": "SPCC16C4.18c", "name": "taf6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13701", "map_id": "O13701", "name": "taf7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13F5.02c", "map_id": "SPAC13F5.02c", "name": "taf7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P17871", "map_id": "P17871", "name": "tbp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60171", "map_id": "O60171", "name": "taf10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC21H7.02", "map_id": "SPBC21H7.02", "name": "taf10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9US54", "map_id": "Q9US54", "name": "taf11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1002.04c", "map_id": "SPAC1002.04c", "name": "taf11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60076", "map_id": "O60076", "name": "taf13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1494.02c", "map_id": "SPCC1494.02c", "name": "taf13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87121", "map_id": "P87121", "name": "taf2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3A12.05c", "map_id": "SPAC3A12.05c", "name": "taf2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09869", "map_id": "Q09869", "name": "taf9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC12G12.05c", "map_id": "SPAC12G12.05c", "name": "taf9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74319", "map_id": "O74319", "name": "taf73", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC15D4.14", "map_id": "SPBC15D4.14", "name": "taf73", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13282", "map_id": "O13282", "name": "taf5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC5E4.03c", "map_id": "SPCC5E4.03c", "name": "taf5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10732998", "map_id": "none", "name": "pol II promoter:TFIID complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733707", "map_id": "none", "name": "Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10732619", "map_id": "none", "name": "TFIIA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9USU9", "map_id": "Q9USU9", "name": "toa1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC28F2.09", "map_id": "SPBC28F2.09", "name": "toa1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74948", "map_id": "O74948", "name": "toa2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC553.11c", "map_id": "SPCC553.11c", "name": "toa2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10732624", "map_id": "O13749", "name": "sua7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC16E8.16", "map_id": "SPAC16E8.16", "name": "sua7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733000", "map_id": "none", "name": "pol II promoter:TFIID:TFIIA:TFIIB complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O13749", "map_id": "O13749", "name": "sua7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10733709", "map_id": "none", "name": "Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10730708", "map_id": "none", "name": "RNA Polymerase II (unphosphorylated):TFIIF complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733002", "map_id": "none", "name": "pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733006", "map_id": "none", "name": "Binding of TFIIE to the growing preinitiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10732711", "map_id": "none", "name": "TFIIE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P79011", "map_id": "P79011", "name": "tfa2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1672.08c", "map_id": "SPCC1672.08c", "name": "tfa2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P3W1", "map_id": "Q9P3W1", "name": "tfa1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC458.07", "map_id": "SPAC458.07", "name": "tfa1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733004", "map_id": "none", "name": "pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733711", "map_id": "none", "name": "Formation of the closed pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733340", "map_id": "none", "name": "pol II closed pre-initiation complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750331", "map_id": "none", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29362", "map_id": "CHEBI:57945", "name": "NADH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113590", "map_id": "CHEBI:17388", "name": "1PYR-5COOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_379717", "map_id": "CHEBI:60039", "name": "L-Pro", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10750328", "map_id": "none", "name": "PYCR2 decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9P7Y7", "map_id": "Q9P7Y7", "name": "pro3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPYUG7.05", "map_id": "SPAPYUG7.05", "name": "pro3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729991", "map_id": "none", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729988", "map_id": "none", "name": "GLUL decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09179", "map_id": "Q09179", "name": "gln1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23H4.06", "map_id": "SPAC23H4.06", "name": "gln1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730012", "map_id": "none", "name": "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113594", "map_id": "CHEBI:16810", "name": "2OG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113585", "map_id": "CHEBI:15729", "name": "L-Orn", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_31339", "map_id": "CHEBI:17232", "name": "L-Glu5S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10730009", "map_id": "none", "name": "OAT hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9P7L5", "map_id": "Q9P7L5", "name": "car2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC21C3.08c", "map_id": "SPBC21C3.08c", "name": "car2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729993", "map_id": "none", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113587", "map_id": "CHEBI:30744", "name": "OAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113553", "map_id": "CHEBI:29991", "name": "L-Asp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10729968", "map_id": "none", "name": "GOT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O94320", "map_id": "O94320", "name": "PXLP-K279-GOT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC725.01", "map_id": "SPBC725.01", "name": "PXLP-K279-GOT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730022", "map_id": "none", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10730019", "map_id": "none", "name": "PYCR1 decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10740180", "map_id": "none", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113548", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10740177", "map_id": "none", "name": "P5CS dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q9UT44", "map_id": "Q9UT44", "name": "pro1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC821.11", "map_id": "SPAC821.11", "name": "pro1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740380", "map_id": "none", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29398", "map_id": "CHEBI:15361", "name": "PYR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_893598", "map_id": "CHEBI:30882", "name": "2OGA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29432", "map_id": "CHEBI:57972", "name": "L-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740371", "map_id": "none", "name": "PXLP-KYAT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14209", "map_id": "O14209", "name": "PXLP-K247-KYAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6B12.04c", "map_id": "SPAC6B12.04c", "name": "PXLP-K247-KYAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750338", "map_id": "none", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_35305", "map_id": "CHEBI:17388", "name": "1PYR-5COOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113538", "map_id": "CHEBI:60039", "name": "L-Pro", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10750335", "map_id": "none", "name": "PYCRL decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10734483", "map_id": "none", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10734481", "map_id": "P00046", "name": "cyc1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10734479", "map_id": "P00046", "name": "cyc1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10752635", "map_id": "none", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10737741", "map_id": "P87057", "name": "nhp6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC57A10.09c", "map_id": "SPAC57A10.09c", "name": "nhp6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10752522", "map_id": "P87057", "name": "nhp6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10745096", "map_id": "none", "name": "HSP70:DNAJB1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744254", "map_id": "none", "name": "HSF1 trimer:target gene", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O14283", "map_id": "O14283", "name": "phospho-prr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC8C9.14", "map_id": "SPAC8C9.14", "name": "phospho-prr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q02953", "map_id": "Q02953", "name": "phospho-hsf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2E12.02", "map_id": "SPAC2E12.02", "name": "phospho-hsf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744224", "map_id": "none", "name": "HSP70:DNAJB1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O59855", "map_id": "O59855", "name": "ssa2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1739.13", "map_id": "SPCC1739.13", "name": "ssa2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09912", "map_id": "Q09912", "name": "psi1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC830.07c", "map_id": "SPCC830.07c", "name": "psi1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10265", "map_id": "Q10265", "name": "ssa1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13G7.02c", "map_id": "SPAC13G7.02c", "name": "ssa1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10061", "map_id": "Q10061", "name": "HSPA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1F5.06", "map_id": "SPAC1F5.06", "name": "HSPA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744256", "map_id": "none", "name": "HSP70:DNAJB1:HSF1 trimer:target gene", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10744320", "map_id": "none", "name": "HSBP1 binds HSF1 trimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744252", "map_id": "none", "name": "HSF1 trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10744316", "map_id": "none", "name": "HSBP1 hexamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O14330", "map_id": "O14330", "name": "HSBP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16E9.15", "map_id": "SPBC16E9.15", "name": "HSBP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744318", "map_id": "none", "name": "HSBP1:HSF1 trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10757482", "map_id": "none", "name": "PTPN7 binds p-T,Y-MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757459", "map_id": "none", "name": "Homologues of PTPN7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P27574", "map_id": "P27574", "name": "pyp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26F1.10c", "map_id": "SPAC26F1.10c", "name": "pyp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32587", "map_id": "P32587", "name": "pyp3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC11E3.09", "map_id": "SPAC11E3.09", "name": "pyp3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32586", "map_id": "P32586", "name": "pyp2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC19D5.01", "map_id": "SPAC19D5.01", "name": "pyp2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757461", "map_id": "none", "name": "PTPN7:p-T,Y-MAPK dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746868", "map_id": "none", "name": "Activated MAPKs phosphorylate MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746838", "map_id": "none", "name": "p-2S MAP2K1:p-2S MAPK2K2 heterodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746865", "map_id": "none", "name": "p-2S,T MAP2K1:p-2S MAPK2K2 heterodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746855", "map_id": "none", "name": "p-T,Y MAPK monomers and dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746885", "map_id": "none", "name": "Nuclear DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746859", "map_id": "none", "name": "p-T,Y MAPK monomers and dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746870", "map_id": "none", "name": "MAPK monomers and dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746872", "map_id": "O13453", "name": "pmp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10757480", "map_id": "none", "name": "PTPN7 dephosphorylates p-T,Y-MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757477", "map_id": "none", "name": "PTPN7:p-T-MAPK dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746906", "map_id": "none", "name": "Cytosolic DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746891", "map_id": "none", "name": "MAPK monomers and dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746893", "map_id": "O13453", "name": "pmp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10745486", "map_id": "none", "name": "RANBP2 SUMOylates MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743716", "map_id": "O74503", "name": "spp27", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPCC285.17", "map_id": "SPCC285.17", "name": "spp27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743647", "map_id": "none", "name": "SUMO1:C93-UBE2I", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O13351", "map_id": "O13351", "name": "pmt3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC365.06", "map_id": "SPBC365.06", "name": "pmt3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40984", "map_id": "P40984", "name": "hus5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC30D11.13", "map_id": "SPAC30D11.13", "name": "hus5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743639", "map_id": "P40984", "name": "hus5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10743724", "map_id": "none", "name": "SUMO1:MDM2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O74503", "map_id": "O74503", "name": "spp27", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743731", "map_id": "none", "name": "PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743726", "map_id": "O94451", "name": "pli1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC1687.05", "map_id": "SPAC1687.05", "name": "pli1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10751267", "map_id": "none", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_417891", "map_id": "CHEBI:52288", "name": "LPA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_6797635", "map_id": "CHEBI:17815", "name": "1,2-DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_109277", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10751264", "map_id": "Q9UUA6", "name": "dpp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPBC409.18", "map_id": "SPBC409.18", "name": "dpp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757778", "map_id": "none", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738115", "map_id": "none", "name": "Microtubule", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P04689", "map_id": "P04689", "name": "tub1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC800.05c", "map_id": "SPBC800.05c", "name": "tub1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P05219", "map_id": "P05219", "name": "nda3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC26H8.07c", "map_id": "SPBC26H8.07c", "name": "nda3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P04688", "map_id": "P04688", "name": "nda2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16A3.15c", "map_id": "SPBC16A3.15c", "name": "nda2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10738111", "map_id": "none", "name": "alpha-beta tubulin dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757769", "map_id": "none", "name": "LEM2D:ESCRT-III:IST1:CC2D1B:SPAST", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "Q9P3U2", "map_id": "Q9P3U2", "name": "SPAST", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC328.04", "map_id": "SPAC328.04", "name": "SPAST", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74422", "map_id": "O74422", "name": "CHMP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC162.06c", "map_id": "SPCC162.06c", "name": "CHMP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14177", "map_id": "O14177", "name": "did4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4F8.01", "map_id": "SPAC4F8.01", "name": "did4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14296", "map_id": "O14296", "name": "vps24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC9E9.14", "map_id": "SPAC9E9.14", "name": "vps24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74490", "map_id": "O74490", "name": "ist1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1442.17c", "map_id": "SPCC1442.17c", "name": "ist1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94318", "map_id": "O94318", "name": "vps20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC215.14c", "map_id": "SPBC215.14c", "name": "vps20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7F7", "map_id": "Q9P7F7", "name": "snf7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1142.07c", "map_id": "SPAC1142.07c", "name": "snf7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743751", "map_id": "none", "name": "UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10743738", "map_id": "none", "name": "RANGAP1 homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "P41391", "map_id": "P41391", "name": "rna1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22E12.07", "map_id": "SPAC22E12.07", "name": "rna1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743748", "map_id": "none", "name": "SUMO1:RANGAP1 homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10757349", "map_id": "none", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1598585", "compartment_display": "chromosome" }, { "id": "species_10737260", "map_id": "none", "name": "RAN:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P28748", "map_id": "P28748", "name": "spi1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1289.03c", "map_id": "SPBC1289.03c", "name": "spi1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745968", "map_id": "none", "name": "RAN:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757346", "map_id": "P28745", "name": "pim1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_1598585", "compartment_display": "chromosome", "complex": "false" }, { "id": "SPBC557.03c", "map_id": "SPBC557.03c", "name": "pim1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757341", "map_id": "none", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10737539", "map_id": "O13864", "name": "kap95", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC1B1.03c", "map_id": "SPAC1B1.03c", "name": "kap95", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757337", "map_id": "Q09195", "name": "phospho-erg24", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "SPBC16G5.18", "map_id": "SPBC16G5.18", "name": "erg24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757339", "map_id": "none", "name": "p-S71,S86-LBR:KPNB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "Q09195", "map_id": "Q09195", "name": "erg24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13864", "map_id": "O13864", "name": "kap95", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757773", "map_id": "none", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740625", "map_id": "Q09803", "name": "vps4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC2G11.06", "map_id": "SPAC2G11.06", "name": "vps4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757771", "map_id": "none", "name": "LEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "Q09803", "map_id": "Q09803", "name": "vps4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743193", "map_id": "none", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743182", "map_id": "P18296", "name": "cut1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC5E4.04", "map_id": "SPCC5E4.04", "name": "cut1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743190", "map_id": "none", "name": "ESPL1 Autocleaved", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P18296", "map_id": "P18296", "name": "cut1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757442", "map_id": "none", "name": "POM121 and NDC1 bind the Nup93 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757438", "map_id": "Q9P7M8", "name": "nup184", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10757311", "map_id": "none", "name": "POM121:Nup107-160 complex:AHCTF1:Chromatin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "species_10733090", "map_id": "O13961", "name": "cut11", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10757436", "map_id": "none", "name": "Nup93 complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757440", "map_id": "none", "name": "Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10757353", "map_id": "none", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9624879", "map_id": "none", "name": "Nuclear envelope vesicle", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10757351", "map_id": "none", "name": "RAN:GTP:Nuclear envelope vesicles", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10743226", "map_id": "none", "name": "PTTG1 (Securin) sequesters ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743222", "map_id": "P21135", "name": "cut2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC14C8.01c", "map_id": "SPBC14C8.01c", "name": "cut2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743224", "map_id": "none", "name": "PTTG1:ESPL1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P21135", "map_id": "P21135", "name": "cut2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757356", "map_id": "none", "name": "RAN stimulates fusion of nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9624890", "map_id": "none", "name": "Fused nuclear envelope vesicles", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "reaction_10757775", "map_id": "none", "name": "SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757757", "map_id": "Q9P3U2", "name": "SPAST", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10757767", "map_id": "none", "name": "LEM2D:ESCRT-III:IST1:CC2D1B", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10757313", "map_id": "none", "name": "POM121 binds the Nup107-Nup160 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757309", "map_id": "none", "name": "Nup107-160 complex:AHCTF1:Chromatin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10733083", "map_id": "Q09904", "name": "nup124", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "reaction_10758064", "map_id": "none", "name": "GMPS dimer transforms 6TXMP to 6TGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9748959", "map_id": "CHEBI:180685", "name": "6TXMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9748970", "map_id": "CHEBI:180686", "name": "6TGMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10758061", "map_id": "none", "name": "GMPS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P772", "map_id": "Q9P772", "name": "gua1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2F12.14c", "map_id": "SPBC2F12.14c", "name": "gua1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10758081", "map_id": "none", "name": "ABCC4 transports TPMP substrates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9750587", "map_id": "none", "name": "ABCC4 TPMP substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_9748992", "map_id": "CHEBI:180684", "name": "6TIMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "pubchem.compound:3037883", "map_id": "pubchem.compound:3037883", "name": "pubchem.compound:3037883", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9750548", "map_id": "none", "name": "ABCC4 TPMP substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:80613", "map_id": "CHEBI:80613", "name": "CHEBI:80613", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:2332", "map_id": "CHEBI:2332", "name": "CHEBI:2332", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741716", "map_id": "none", "name": "Homologues of ABCC4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q92337", "map_id": "Q92337", "name": "abc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC9E9.12c", "map_id": "SPAC9E9.12c", "name": "abc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7V2", "map_id": "Q9P7V2", "name": "abc4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC30.04c", "map_id": "SPAC30.04c", "name": "abc4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10758059", "map_id": "none", "name": "GUK1 phosphorylates 6TGMP to 6TGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9748960", "map_id": "CHEBI:180687", "name": "6TGDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10758057", "map_id": "none", "name": "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10732525", "map_id": "none", "name": "IMPDH1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14344", "map_id": "O14344", "name": "gua1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10758087", "map_id": "none", "name": "ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9753559", "map_id": "none", "name": "APAP-GlcA, APAP-SO3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:32635", "map_id": "CHEBI:32635", "name": "CHEBI:32635", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:132962", "map_id": "CHEBI:132962", "name": "CHEBI:132962", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9753562", "map_id": "none", "name": "APAP-GlcA, APAP-SO3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:32636", "map_id": "CHEBI:32636", "name": "CHEBI:32636", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741710", "map_id": "none", "name": "Homologues of ABCC2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q10185", "map_id": "Q10185", "name": "abc2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3F10.11c", "map_id": "SPAC3F10.11c", "name": "abc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P5N0", "map_id": "Q9P5N0", "name": "abc3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC359.05", "map_id": "SPBC359.05", "name": "abc3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10758096", "map_id": "none", "name": "CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9753680", "map_id": "CHEBI:180460", "name": "APAP-CysGly", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9753653", "map_id": "CHEBI:133067", "name": "APAP-Cys", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_29424", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10741586", "map_id": "none", "name": "CNDP2:2Mn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P6I2", "map_id": "Q9P6I2", "name": "dug1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1198.08", "map_id": "SPBC1198.08", "name": "dug1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10758070", "map_id": "none", "name": "NME1:2 hexamer phosphorylates 6TGDP to 6TGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9748947", "map_id": "CHEBI:180688", "name": "6TGTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10758089", "map_id": "none", "name": "ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10758068", "map_id": "none", "name": "NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9749033", "map_id": "CHEBI:180690", "name": "6TdGDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9749032", "map_id": "CHEBI:180691", "name": "6TdGTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10758084", "map_id": "none", "name": "ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9750692", "map_id": "none", "name": "salicylate metabolites", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:9008", "map_id": "CHEBI:9008", "name": "CHEBI:9008", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:58044", "map_id": "CHEBI:58044", "name": "CHEBI:58044", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:88742", "map_id": "CHEBI:88742", "name": "CHEBI:88742", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:176976", "map_id": "CHEBI:176976", "name": "CHEBI:176976", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:36654", "map_id": "CHEBI:36654", "name": "CHEBI:36654", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:176960", "map_id": "CHEBI:176960", "name": "CHEBI:176960", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9750678", "map_id": "none", "name": "salicylate metabolites", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10742965", "map_id": "none", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2161185", "map_id": "LigandDisplayForward?ligandId=11152", "name": "abacavir", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2162081", "map_id": "CHEBI:64192", "name": "abacavir 5'-carboxylic acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730504", "map_id": "none", "name": "ADH1A:2Zn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78870", "map_id": "P78870", "name": "ADH1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC13B11.04c", "map_id": "SPCC13B11.04c", "name": "ADH1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74540", "map_id": "O74540", "name": "ADH1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10758066", "map_id": "none", "name": "GUK1 phosphorylates 6TdGMP to 6TdGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9749031", "map_id": "CHEBI:180689", "name": "6TdGMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10758098", "map_id": "none", "name": "GGT dimers hydrolyse APAP-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9753685", "map_id": "CHEBI:32639", "name": "APAP-SG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745932", "map_id": "none", "name": "GGT dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O14194", "map_id": "O14194", "name": "ggt2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC56E4.06c", "map_id": "SPAC56E4.06c", "name": "ggt2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9US04", "map_id": "Q9US04", "name": "ggt1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC664.09", "map_id": "SPAC664.09", "name": "ggt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10758094", "map_id": "none", "name": "ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9753629", "map_id": "none", "name": "APAP-Cys,APAP-Mer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:133438", "map_id": "CHEBI:133438", "name": "CHEBI:133438", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9753624", "map_id": "none", "name": "APAP-Cys,APAP-Mer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:133066", "map_id": "CHEBI:133066", "name": "CHEBI:133066", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:133435", "map_id": "CHEBI:133435", "name": "CHEBI:133435", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10758091", "map_id": "none", "name": "ABCC1,4,5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10735847", "map_id": "none", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_188458", "map_id": "CHEBI:15978", "name": "G3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_188451", "map_id": "CHEBI:57642", "name": "DHAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_31649", "map_id": "CHEBI:17877", "name": "FADH2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10735844", "map_id": "O14400", "name": "gut2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPCC1223.03c", "map_id": "SPCC1223.03c", "name": "gut2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738355", "map_id": "none", "name": "Activation of PAKs by RAC1 and CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738349", "map_id": "none", "name": "PAK1,2,3 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10056", "map_id": "Q10056", "name": "shk2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1F5.09c", "map_id": "SPAC1F5.09c", "name": "shk2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50527", "map_id": "P50527", "name": "shk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1604.14c", "map_id": "SPBC1604.14c", "name": "shk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10738231", "map_id": "none", "name": "CDC42:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q01112", "map_id": "Q01112", "name": "cdc42", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC110.03", "map_id": "SPAC110.03", "name": "cdc42", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10738353", "map_id": "none", "name": "PAK1,2,3:CDC42:GTP, RAC1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10738351", "map_id": "none", "name": "PAK1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10741676", "map_id": "none", "name": "Phosphorylation of USP8 by P-AKT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741666", "map_id": "none", "name": "Homologues of USP8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O60079", "map_id": "O60079", "name": "phospho-ubp12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1494.05c", "map_id": "SPCC1494.05c", "name": "phospho-ubp12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USM5", "map_id": "Q9USM5", "name": "phospho-ubp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC16A11.12c", "map_id": "SPCC16A11.12c", "name": "phospho-ubp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741674", "map_id": "none", "name": "Homologues of p-T945-USP8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757404", "map_id": "none", "name": "SEPT4 binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757400", "map_id": "none", "name": "SEPT4 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09883", "map_id": "Q09883", "name": "spn6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC188.12", "map_id": "SPCC188.12", "name": "spn6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P48010", "map_id": "P48010", "name": "spn5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC24C9.15c", "map_id": "SPAC24C9.15c", "name": "spn5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P48008", "map_id": "P48008", "name": "spn3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16A3.01", "map_id": "SPBC16A3.01", "name": "spn3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60165", "map_id": "O60165", "name": "spn7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19F8.01c", "map_id": "SPBC19F8.01c", "name": "spn7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P48009", "map_id": "P48009", "name": "spn4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC9G1.11c", "map_id": "SPAC9G1.11c", "name": "spn4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O36023", "map_id": "O36023", "name": "spn1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4F10.11", "map_id": "SPAC4F10.11", "name": "spn1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745678", "map_id": "O14064", "name": "bir1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC962.02c", "map_id": "SPCC962.02c", "name": "bir1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757402", "map_id": "none", "name": "SEPT4 dimer:XIAP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14064", "map_id": "O14064", "name": "bir1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732312", "map_id": "none", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_73578", "map_id": "CHEBI:78346", "name": "R5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_73566", "map_id": "CHEBI:58017", "name": "PRPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732309", "map_id": "none", "name": "PRPS2 dimer, PRPS1L dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94413", "map_id": "O94413", "name": "PRPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1620.06c", "map_id": "SPCC1620.06c", "name": "PRPS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41831", "map_id": "P41831", "name": "PRPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87171", "map_id": "P87171", "name": "PRPS1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735815", "map_id": "none", "name": "ribose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29732", "map_id": "CHEBI:17363", "name": "RU5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730283", "map_id": "Q9UTL3", "name": "rki1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC144.12", "map_id": "SPAC144.12", "name": "rki1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730278", "map_id": "none", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29790", "map_id": "CHEBI:57737", "name": "XY5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730275", "map_id": "none", "name": "RPE:Fe2+ dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14105", "map_id": "O14105", "name": "RPE", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC31G5.05c", "map_id": "SPAC31G5.05c", "name": "RPE", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750445", "map_id": "none", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_112016", "map_id": "CHEBI:57720", "name": "R1P", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10729638", "map_id": "none", "name": "PGM2:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74478", "map_id": "O74478", "name": "PGM2L1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1840.05c", "map_id": "SPCC1840.05c", "name": "PGM2L1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734989", "map_id": "none", "name": "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29878", "map_id": "CHEBI:16897", "name": "E4P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29512", "map_id": "CHEBI:57634", "name": "Fru(6)P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29578", "map_id": "CHEBI:59776", "name": "GA3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29882", "map_id": "CHEBI:15721", "name": "SH7P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730293", "map_id": "none", "name": "TALDO1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42700", "map_id": "O42700", "name": "tal1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1020.06c", "map_id": "SPCC1020.06c", "name": "tal1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736696", "map_id": "none", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10730248", "map_id": "none", "name": "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_31467", "map_id": "CHEBI:16938", "name": "D-Glucono-1,5-lactone 6-phosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29996", "map_id": "CHEBI:16863", "name": "PDG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730245", "map_id": "O74455", "name": "PGLS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC16C4.10", "map_id": "SPCC16C4.10", "name": "PGLS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730258", "map_id": "none", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10730255", "map_id": "none", "name": "PGD dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78812", "map_id": "P78812", "name": "PGD", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC660.16", "map_id": "SPBC660.16", "name": "PGD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729691", "map_id": "none", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30537", "map_id": "CHEBI:58225", "name": "G6P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729688", "map_id": "none", "name": "G6PD dimer and tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O00091", "map_id": "O00091", "name": "zwf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3A12.18", "map_id": "SPAC3A12.18", "name": "zwf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756527", "map_id": "none", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6787326", "map_id": "CHEBI:11563", "name": "dR1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6787328", "map_id": "CHEBI:16132", "name": "dR5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10756433", "map_id": "none", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8955853", "map_id": "CHEBI:47013", "name": "D-ribose", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10756430", "map_id": "O60116", "name": "rbk1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC16G5.02c", "map_id": "SPBC16G5.02c", "name": "rbk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734063", "map_id": "none", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10732305", "map_id": "none", "name": "PRPS1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10743558", "map_id": "none", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742830", "map_id": "none", "name": "Calcineurin (CaN)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UU93", "map_id": "Q9UU93", "name": "cnb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC830.06", "map_id": "SPCC830.06", "name": "cnb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q12705", "map_id": "Q12705", "name": "ppb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP4H10.04", "map_id": "SPBP4H10.04", "name": "ppb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10737034", "map_id": "none", "name": "CALM1:4xCa2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10743532", "map_id": "none", "name": "Calcineurin:Calmodulin (CaN:CaM)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10744811", "map_id": "none", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744805", "map_id": "none", "name": "NFATC1:CaN:CaM", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10744809", "map_id": "none", "name": "NFATC1:CaN:CaM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10743992", "map_id": "none", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10743986", "map_id": "none", "name": "WLS:retromer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_171062", "compartment_display": "early endosome membrane", "complex": "true" }, { "id": "Q9UTI5", "map_id": "Q9UTI5", "name": "vps29", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC15E1.06", "map_id": "SPAC15E1.06", "name": "vps29", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74552", "map_id": "O74552", "name": "vps35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC777.13", "map_id": "SPCC777.13", "name": "vps35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94291", "map_id": "O94291", "name": "snx3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC887.06c", "map_id": "SPBC887.06c", "name": "snx3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10243", "map_id": "Q10243", "name": "vps26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4G9.13c", "map_id": "SPAC4G9.13c", "name": "vps26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743990", "map_id": "none", "name": "WLS:retromer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10750278", "map_id": "none", "name": "DNA polymerases delta, epsilon or kappa bind the TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10749283", "map_id": "none", "name": "POLD,POLE,POLK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P87154", "map_id": "P87154", "name": "pol2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC25H2.13c", "map_id": "SPBC25H2.13c", "name": "pol2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87174", "map_id": "P87174", "name": "dpb4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3D6.09", "map_id": "SPBC3D6.09", "name": "dpb4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59835", "map_id": "O59835", "name": "cdm1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC12D12.02c", "map_id": "SPBC12D12.02c", "name": "cdm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94263", "map_id": "O94263", "name": "dpb2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP8B7.14c", "map_id": "SPBP8B7.14c", "name": "dpb2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P30261", "map_id": "P30261", "name": "cdc27", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1734.02c", "map_id": "SPBC1734.02c", "name": "cdc27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74944", "map_id": "O74944", "name": "mug40", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC553.07c", "map_id": "SPCC553.07c", "name": "mug40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87324", "map_id": "P87324", "name": "cdc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27E2.05", "map_id": "SPAC27E2.05", "name": "cdc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P30316", "map_id": "P30316", "name": "pol3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC336.04", "map_id": "SPBC336.04", "name": "pol3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6Y4D0", "map_id": "C6Y4D0", "name": "dpb3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC16C4.22", "map_id": "SPCC16C4.22", "name": "dpb3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749285", "map_id": "none", "name": "PCNA homotrimer,MonoUb:K164-PCNA homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10750264", "map_id": "none", "name": "TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q92373", "map_id": "Q92373", "name": "ssb2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1753.01c", "map_id": "SPCC1753.01c", "name": "ssb2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36617", "map_id": "P36617", "name": "rad16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC970.01", "map_id": "SPCC970.01", "name": "rad16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q06182", "map_id": "Q06182", "name": "swi10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4F6.15c", "map_id": "SPBC4F6.15c", "name": "swi10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q92374", "map_id": "Q92374", "name": "ssb3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC23B6.05c", "map_id": "SPCC23B6.05c", "name": "ssb3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q92372", "map_id": "Q92372", "name": "ssb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC660.13c", "map_id": "SPBC660.13c", "name": "ssb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P28706", "map_id": "P28706", "name": "rad13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3E7.08c", "map_id": "SPBC3E7.08c", "name": "rad13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10729448", "map_id": "none", "name": "RFC Heteropentamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O94697", "map_id": "O94697", "name": "rfc5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC83.14c", "map_id": "SPBC83.14c", "name": "rfc5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94449", "map_id": "O94449", "name": "rfc4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1687.03c", "map_id": "SPAC1687.03c", "name": "rfc4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09843", "map_id": "Q09843", "name": "rfc2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23D3.02", "map_id": "SPAC23D3.02", "name": "rfc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14003", "map_id": "O14003", "name": "rfc3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27E2.10c", "map_id": "SPAC27E2.10c", "name": "rfc3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60182", "map_id": "O60182", "name": "rfc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC23E6.07c", "map_id": "SPBC23E6.07c", "name": "rfc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750276", "map_id": "none", "name": "TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750246", "map_id": "none", "name": "ERCC2-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10750243", "map_id": "none", "name": "TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750267", "map_id": "none", "name": "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10750260", "map_id": "none", "name": "TC-NER incision complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750258", "map_id": "none", "name": "ERCC5 and RPA bind TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747765", "map_id": "P28706", "name": "rad13", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10750254", "map_id": "none", "name": "TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729504", "map_id": "none", "name": "RPA heterotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10750256", "map_id": "none", "name": "TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750262", "map_id": "none", "name": "Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733829", "map_id": "none", "name": "ERCC1:ERCC4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10757829", "map_id": "none", "name": "ERCC3-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10750281", "map_id": "none", "name": "3' incision by ERCC5 (XPG) in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10750269", "map_id": "none", "name": "TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10747770", "map_id": "O59753", "name": "rhp14", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10740162", "map_id": "none", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_29514", "map_id": "CHEBI:16199", "name": "Urea", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_432019", "map_id": "CHEBI:16199", "name": "Urea", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10740159", "map_id": "none", "name": "AQP9,10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9P7T9", "map_id": "Q9P7T9", "name": "AQP10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC977.17", "map_id": "SPAC977.17", "name": "AQP10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739398", "map_id": "none", "name": "VMAT1/2 can mediate the transport of biogenic amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_444154", "map_id": "none", "name": "Biogenic amines transported by VMAT1/2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:18295", "map_id": "CHEBI:18295", "name": "CHEBI:18295", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_351601", "map_id": "CHEBI:18243", "name": "DA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_374932", "compartment_display": "clathrin-sculpted monoamine transport vesicle lumen", "complex": "false" }, { "id": "CHEBI:18357", "map_id": "CHEBI:18357", "name": "CHEBI:18357", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:28918", "map_id": "CHEBI:28918", "name": "CHEBI:28918", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_209914", "map_id": "CHEBI:28790", "name": "5HT", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_444152", "map_id": "none", "name": "Biogenic amines transported by VMAT1/2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_374932", "compartment_display": "clathrin-sculpted monoamine transport vesicle lumen", "complex": "true" }, { "id": "species_10739395", "map_id": "none", "name": "VMAT1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_374940", "compartment_display": "clathrin-sculpted monoamine transport vesicle membrane", "complex": "true" }, { "id": "reaction_10739315", "map_id": "none", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_446589", "map_id": "none", "name": "MATE substrates", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:8428", "map_id": "CHEBI:8428", "name": "CHEBI:8428", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:46020", "map_id": "CHEBI:46020", "name": "CHEBI:46020", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:42820", "map_id": "CHEBI:42820", "name": "CHEBI:42820", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16737", "map_id": "CHEBI:16737", "name": "CHEBI:16737", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=1231", "map_id": "LigandDisplayForward?ligandId=1231", "name": "LigandDisplayForward?ligandId=1231", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:641", "map_id": "CHEBI:641", "name": "CHEBI:641", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:6801", "map_id": "CHEBI:6801", "name": "CHEBI:6801", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_446597", "map_id": "none", "name": "MATE substrates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10739312", "map_id": "none", "name": "MATE1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9USK3", "map_id": "Q9USK3", "name": "SLC47A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC4B3.13", "map_id": "SPCC4B3.13", "name": "SLC47A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10085", "map_id": "Q10085", "name": "SLC47A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UT92", "map_id": "Q9UT92", "name": "SLC47A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740155", "map_id": "none", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10740147", "map_id": "none", "name": "AQP0,1,2,3,4,5,7,8,9,10,11,12A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10756479", "map_id": "none", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29418", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_266099", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10756476", "map_id": "O13918", "name": "zhf1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPAC23C11.14", "map_id": "SPAC23C11.14", "name": "zhf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740289", "map_id": "none", "name": "SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_742368", "map_id": "CHEBI:17009", "name": "GDP-Fuc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_205683", "map_id": "CHEBI:17009", "name": "GDP-Fuc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10740286", "map_id": "Q9UUI8", "name": "SLC35C1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "SPAC22F8.04", "map_id": "SPAC22F8.04", "name": "SLC35C1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739323", "map_id": "none", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_29426", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_158417", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10739320", "map_id": "O13918", "name": "zhf1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10740865", "map_id": "none", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_947594", "map_id": "none", "name": "APLs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_947586", "compartment_display": "external side of plasma membrane", "complex": "true" }, { "id": "species_1500646", "map_id": "CHEBI:18303", "name": "PS", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_1500581", "map_id": "CHEBI:16038", "name": "PE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_947588", "map_id": "none", "name": "APLs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_947587", "compartment_display": "cytoplasmic side of plasma membrane", "complex": "true" }, { "id": "species_10740862", "map_id": "none", "name": "P-type ATPases type IV", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q10309", "map_id": "Q10309", "name": "ATP9A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6C3.06c", "map_id": "SPAC6C3.06c", "name": "ATP9A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UT43", "map_id": "Q9UT43", "name": "ATP11C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC887.12", "map_id": "SPBC887.12", "name": "ATP11C", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O36028", "map_id": "O36028", "name": "ATP8B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4F10.16c", "map_id": "SPAC4F10.16c", "name": "ATP8B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94296", "map_id": "O94296", "name": "ATP11C", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09891", "map_id": "Q09891", "name": "ATP8B2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC24B11.12c", "map_id": "SPAC24B11.12c", "name": "ATP8B2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740157", "map_id": "none", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_192438", "map_id": "CHEBI:17754", "name": "glycerol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10747160", "map_id": "none", "name": "CFTR transports Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738217", "map_id": "none", "name": "Homologues of CFTR", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10745661", "map_id": "none", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_109496", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10745658", "map_id": "P87149", "name": "mrs2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPBC25H2.08c", "map_id": "SPBC25H2.08c", "name": "mrs2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745601", "map_id": "none", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5252122", "map_id": "CHEBI:60240", "name": "divalent metal cation", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_5252016", "map_id": "CHEBI:60240", "name": "divalent metal cation", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745598", "map_id": "none", "name": "ATP13A4, 5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O74431", "map_id": "O74431", "name": "ATP13A2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1672.11c", "map_id": "SPCC1672.11c", "name": "ATP13A2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14022", "map_id": "O14022", "name": "cta5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC29A4.19c", "map_id": "SPAC29A4.19c", "name": "cta5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739257", "map_id": "none", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10739254", "map_id": "none", "name": "AQP9 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10740300", "map_id": "none", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_742353", "map_id": "CHEBI:16082", "name": "UDP-Xyl", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_742361", "map_id": "CHEBI:16082", "name": "UDP-Xyl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10740294", "map_id": "O74750", "name": "yea4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "SPBC1734.09", "map_id": "SPBC1734.09", "name": "yea4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740787", "map_id": "none", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_167012", "map_id": "CHEBI:29108", "name": "Ca2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10740784", "map_id": "none", "name": "ATP2C1/2:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "O59868", "map_id": "O59868", "name": "pmr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC31E1.02c", "map_id": "SPBC31E1.02c", "name": "pmr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739115", "map_id": "none", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429130", "map_id": "CHEBI:17268", "name": "Ins", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_426910", "map_id": "CHEBI:17268", "name": "Ins", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739112", "map_id": "Q10286", "name": "itr1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPAC4F8.15", "map_id": "SPAC4F8.15", "name": "itr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739331", "map_id": "none", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen" }, { "id": "species_216785", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "false" }, { "id": "species_10739328", "map_id": "Q9HGQ3", "name": "cis4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "false" }, { "id": "SPAC17D4.03c", "map_id": "SPAC17D4.03c", "name": "cis4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740662", "map_id": "none", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_74722", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171907", "compartment_display": "endosome lumen", "complex": "false" }, { "id": "species_10732848", "map_id": "none", "name": "V-ATPase:ATP6AP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10749527", "map_id": "none", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5692450", "map_id": "CHEBI:36916", "name": "cation", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5692484", "map_id": "CHEBI:36916", "name": "cation", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10749524", "map_id": "none", "name": "Homologues of ATP13A2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10754737", "map_id": "none", "name": "misfolded CFTR is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10754735", "map_id": "none", "name": "Ub-misfolded nascent CFTR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10740153", "map_id": "none", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10755496", "map_id": "none", "name": "SLC45A3 transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_70115", "map_id": "CHEBI:17925", "name": "Glc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_70113", "map_id": "CHEBI:17925", "name": "Glc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10755493", "map_id": "O14091", "name": "sut1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPAC2F3.08", "map_id": "SPAC2F3.08", "name": "sut1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745471", "map_id": "none", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5223341", "map_id": "none", "name": "23mer peptide", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5223344", "map_id": "none", "name": "23mer peptide", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10745468", "map_id": "none", "name": "ABCB9 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "P78966", "map_id": "P78966", "name": "mam1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC25B2.02c", "map_id": "SPBC25B2.02c", "name": "mam1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745674", "map_id": "none", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_114632", "map_id": "CHEBI:18420", "name": "Mg2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10745671", "map_id": "Q8TFH3", "name": "ost3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPAPB17E12.11", "map_id": "SPAPB17E12.11", "name": "ost3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738200", "map_id": "none", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_113521", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_71185", "map_id": "CHEBI:17627", "name": "heme", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10738197", "map_id": "none", "name": "Heme transporters", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "O14286", "map_id": "O14286", "name": "atm1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC15A10.01", "map_id": "SPAC15A10.01", "name": "atm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739371", "map_id": "none", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10739368", "map_id": "Q9UT11", "name": "SLC39A7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAP8A3.03", "map_id": "SPAP8A3.03", "name": "SLC39A7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743495", "map_id": "none", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743492", "map_id": "none", "name": "ANOs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O13621", "map_id": "O13621", "name": "ANO10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC691.05c", "map_id": "SPBC691.05c", "name": "ANO10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739417", "map_id": "none", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10739414", "map_id": "none", "name": "AQP3 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10740665", "map_id": "none", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9707310", "map_id": "none", "name": "Hemes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:36144", "map_id": "CHEBI:36144", "name": "CHEBI:36144", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9707308", "map_id": "none", "name": "Hemes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10736861", "map_id": "O13714", "name": "SLC46A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPAC14C4.07", "map_id": "SPAC14C4.07", "name": "SLC46A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741727", "map_id": "none", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1454930", "map_id": "CHEBI:25696", "name": "organic anion", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1454919", "map_id": "CHEBI:25696", "name": "organic anion", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10741724", "map_id": "none", "name": "ABCCs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10740150", "map_id": "none", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10738220", "map_id": "none", "name": "HCO3- transport through ion channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10745669", "map_id": "none", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10745666", "map_id": "Q8TFH3", "name": "ost3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10743514", "map_id": "none", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2731008", "map_id": "CHEBI:17996", "name": "Cl-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_171907", "compartment_display": "endosome lumen", "complex": "false" }, { "id": "species_10743511", "map_id": "none", "name": "CLCN4/5/6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "O94287", "map_id": "O94287", "name": "CLCN5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC887.02", "map_id": "SPBC887.02", "name": "CLCN5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60159", "map_id": "O60159", "name": "CLCN4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19C7.11", "map_id": "SPBC19C7.11", "name": "CLCN4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739264", "map_id": "none", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10739261", "map_id": "none", "name": "AQP7 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10749518", "map_id": "none", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1981162", "map_id": "CHEBI:29035", "name": "Mn2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10749515", "map_id": "O14072", "name": "cta4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPACUNK4.07c", "map_id": "SPACUNK4.07c", "name": "cta4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10754739", "map_id": "none", "name": "CFTR transits to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10754733", "map_id": "none", "name": "Homologues of misfolded CFTR", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10739339", "map_id": "none", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_209799", "map_id": "CHEBI:29036", "name": "Cu2+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739336", "map_id": "Q9USV7", "name": "ctr6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPBC23G7.16", "map_id": "SPBC23G7.16", "name": "ctr6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749496", "map_id": "none", "name": "CANDI binds CUL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10749492", "map_id": "Q9P3A8", "name": "knd1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC1565.07c", "map_id": "SPAC1565.07c", "name": "knd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735499", "map_id": "O13790", "name": "cul1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10749494", "map_id": "none", "name": "CANDI:CUL1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P3A8", "map_id": "Q9P3A8", "name": "knd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740297", "map_id": "none", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_162756", "map_id": "CHEBI:16264", "name": "UDP-GlcNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_914003", "map_id": "CHEBI:16264", "name": "UDP-GlcNAc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "reaction_10740281", "map_id": "none", "name": "SLC35A3 exchanges UDP-GlcNAc for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_735698", "map_id": "CHEBI:57865", "name": "UMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10740278", "map_id": "P87041", "name": "gms1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "SPCC1795.03", "map_id": "SPCC1795.03", "name": "gms1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734940", "map_id": "none", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10734937", "map_id": "none", "name": "SLC25A5 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q09188", "map_id": "Q09188", "name": "anc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC530.10c", "map_id": "SPBC530.10c", "name": "anc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741748", "map_id": "none", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1131652", "map_id": "CHEBI:35703", "name": "a xenobiotic", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1467459", "map_id": "CHEBI:35703", "name": "a xenobiotic", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10741745", "map_id": "none", "name": "ABCA8/B1/B5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10740795", "map_id": "none", "name": "ATP7B transports cytosolic Cu2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_936901", "map_id": "CHEBI:29036", "name": "Cu2+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10740792", "map_id": "O59666", "name": "ccc2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "SPBC29A3.01", "map_id": "SPBC29A3.01", "name": "ccc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740273", "map_id": "none", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_76183", "map_id": "CHEBI:57288", "name": "Ac-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_727753", "map_id": "CHEBI:57288", "name": "Ac-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10740270", "map_id": "Q9USW4", "name": "SLC33A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "SPBC21B10.09", "map_id": "SPBC21B10.09", "name": "SLC33A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740164", "map_id": "none", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10747157", "map_id": "none", "name": "ABCB4 transports PC from plasma membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_429802", "map_id": "CHEBI:16110", "name": "PC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_382539", "map_id": "CHEBI:16110", "name": "PC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10747154", "map_id": "none", "name": "Homologues of ABCB4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10755815", "map_id": "none", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8932838", "map_id": "none", "name": "L-Arg,L-His,L-Lys", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_1131871", "map_id": "CHEBI:32551", "name": "L-lysine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_459", "compartment_display": "cytoplasm", "complex": "false" }, { "id": "species_8932842", "map_id": "none", "name": "L-Arg,L-His,L-Lys", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755812", "map_id": "Q10482", "name": "stm1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "SPAC17C9.10", "map_id": "SPAC17C9.10", "name": "stm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757945", "map_id": "none", "name": "RND1 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738543", "map_id": "none", "name": "RND1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9HE04", "map_id": "Q9HE04", "name": "rho5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC20H4.11c", "map_id": "SPAC20H4.11c", "name": "rho5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09914", "map_id": "Q09914", "name": "rho1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1F7.04", "map_id": "SPAC1F7.04", "name": "rho1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13928", "map_id": "O13928", "name": "rho3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23C4.08", "map_id": "SPAC23C4.08", "name": "rho3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q874R1", "map_id": "Q874R1", "name": "rho4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC16A10.04", "map_id": "SPAC16A10.04", "name": "rho4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10133", "map_id": "Q10133", "name": "rho2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC16.01", "map_id": "SPAC16.01", "name": "rho2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757941", "map_id": "none", "name": "RND1 effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UTL2", "map_id": "Q9UTL2", "name": "klp8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC144.14", "map_id": "SPAC144.14", "name": "klp8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USZ0", "map_id": "Q9USZ0", "name": "WDR6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1306.02", "map_id": "SPBC1306.02", "name": "WDR6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USR1", "map_id": "Q9USR1", "name": "txl1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC577.08c", "map_id": "SPBC577.08c", "name": "txl1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USI5", "map_id": "Q9USI5", "name": "sti1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC645.14c", "map_id": "SPCC645.14c", "name": "sti1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P08647", "map_id": "P08647", "name": "ras1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17H9.09c", "map_id": "SPAC17H9.09c", "name": "ras1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43023", "map_id": "O43023", "name": "TFRC(1-760)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC354.09c", "map_id": "SPBC354.09c", "name": "TFRC(1-760)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757943", "map_id": "none", "name": "RND1:GTP:RND1 effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10757947", "map_id": "none", "name": "RND1 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738541", "map_id": "none", "name": "Homologues of RND1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10733685", "map_id": "none", "name": "Binding of TFIIIC to Type 2 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733480", "map_id": "none", "name": "TFIIIC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O13650", "map_id": "O13650", "name": "sfc9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC8D2.07c", "map_id": "SPBC8D2.07c", "name": "sfc9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UST7", "map_id": "Q9UST7", "name": "sfc3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC336.07", "map_id": "SPBC336.07", "name": "sfc3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74458", "map_id": "O74458", "name": "sfc4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC16C4.14c", "map_id": "SPCC16C4.14c", "name": "sfc4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A6X980", "map_id": "A6X980", "name": "sfc7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1250.07", "map_id": "SPAC1250.07", "name": "sfc7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60174", "map_id": "O60174", "name": "sfc6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC21H7.05", "map_id": "SPBC21H7.05", "name": "sfc6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14229", "map_id": "O14229", "name": "sfc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6F12.11c", "map_id": "SPAC6F12.11c", "name": "sfc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_83747", "map_id": "none", "name": "DNA with RNA Polymerase III Type 2 Closed Promoter", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10733683", "map_id": "none", "name": "TFIIIC:Type 2 Promoter Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733689", "map_id": "none", "name": "Binding of TFIIIB to TFIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733448", "map_id": "none", "name": "TFIIIB-Type 1 and 2 Promoter Selective Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O94481", "map_id": "O94481", "name": "bdp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1919.14c", "map_id": "SPCC1919.14c", "name": "bdp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P6R0", "map_id": "Q9P6R0", "name": "brf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC13E7.10c", "map_id": "SPBC13E7.10c", "name": "brf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733687", "map_id": "none", "name": "TFIIIB:TFIIIC:Type 2 Promoter Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733681", "map_id": "none", "name": "Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733484", "map_id": "none", "name": "TFIIIC:TFIIIA:Type I Promoter Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733486", "map_id": "none", "name": "TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733547", "map_id": "none", "name": "Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733543", "map_id": "none", "name": "RNA Polymerase III Holoenzyme", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O13896", "map_id": "O13896", "name": "rpc11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22A12.05", "map_id": "SPAC22A12.05", "name": "rpc11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94616", "map_id": "O94616", "name": "rpc40", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1289.07c", "map_id": "SPBC1289.07c", "name": "rpc40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94553", "map_id": "O94553", "name": "rpc6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC290.02", "map_id": "SPCC290.02", "name": "rpc6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9C106", "map_id": "Q9C106", "name": "rpc82", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB1E7.03", "map_id": "SPAPB1E7.03", "name": "rpc82", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8WZJ8", "map_id": "Q8WZJ8", "name": "rpc31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC839.12", "map_id": "SPBC839.12", "name": "rpc31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9C0Z9", "map_id": "Q9C0Z9", "name": "rpc17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB1E7.10", "map_id": "SPAPB1E7.10", "name": "rpc17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94666", "map_id": "O94666", "name": "rpc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC651.08c", "map_id": "SPBC651.08c", "name": "rpc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94285", "map_id": "O94285", "name": "rpc25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2G5.07c", "map_id": "SPBC2G5.07c", "name": "rpc25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10233", "map_id": "Q10233", "name": "rpc2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4G9.08c", "map_id": "SPAC4G9.08c", "name": "rpc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74857", "map_id": "O74857", "name": "rpc53", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC18.07", "map_id": "SPCC18.07", "name": "rpc53", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733545", "map_id": "none", "name": "RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733693", "map_id": "none", "name": "Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733691", "map_id": "none", "name": "RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Promoter Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10736346", "map_id": "none", "name": "Dynamin is recruited to the gap junction plaque", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10736046", "map_id": "none", "name": "Dynamin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10736019", "map_id": "none", "name": "planar gap junction plaques associated with Dab2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O60054", "map_id": "O60054", "name": "arp10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC56F2.03", "map_id": "SPBC56F2.03", "name": "arp10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P10989", "map_id": "P10989", "name": "act1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC32H8.12c", "map_id": "SPBC32H8.12c", "name": "act1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10736048", "map_id": "none", "name": "Planar gap junction plaques associated with Dab2 and Dynamin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10739285", "map_id": "none", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_76194", "map_id": "CHEBI:57287", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_3632881", "map_id": "CHEBI:15756", "name": "PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_200993", "map_id": "CHEBI:15525", "name": "PALM-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739282", "map_id": "none", "name": "ACSL3,4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "Q9P7D7", "map_id": "Q9P7D7", "name": "lcf2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP4H10.11c", "map_id": "SPBP4H10.11c", "name": "lcf2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60135", "map_id": "O60135", "name": "lcf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC18H10.02", "map_id": "SPBC18H10.02", "name": "lcf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737145", "map_id": "none", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10734488", "map_id": "Q09914", "name": "rho1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10737143", "map_id": "none", "name": "PIP3:RhoA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10742675", "map_id": "none", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_2023856", "map_id": "CHEBI:18348", "name": "PI(4,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1500596", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10742672", "map_id": "none", "name": "PLCD4:3xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10742665", "map_id": "none", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_994170", "map_id": "CHEBI:16783", "name": "I(1,3,4,5)P4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10742662", "map_id": "none", "name": "PTEN:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94526", "map_id": "O94526", "name": "phospho-ptn1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742633", "map_id": "none", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_114519", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10742630", "map_id": "none", "name": "PLCbz", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742706", "map_id": "none", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10742703", "map_id": "none", "name": "PLCdegh", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10742681", "map_id": "none", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_994123", "map_id": "CHEBI:18228", "name": "I(1,3,4)P3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10742605", "map_id": "none", "name": "INPP5(4)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756065", "map_id": "none", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1247892", "map_id": "CHEBI:16856", "name": "GSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_210382", "map_id": "CHEBI:29985", "name": "L-Glu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_1247934", "map_id": "CHEBI:4047", "name": "CysGly", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10741599", "map_id": "none", "name": "OPLAH hydrolyses OPRO to L-Glu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1247942", "map_id": "CHEBI:18183", "name": "OPRO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10741596", "map_id": "none", "name": "OPLAH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10094", "map_id": "Q10094", "name": "OPLAH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC11D3.15", "map_id": "SPAC11D3.15", "name": "OPLAH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741589", "map_id": "none", "name": "CNDP2:2Mn2+ dimer hydrolyses CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1247904", "map_id": "CHEBI:4047", "name": "CysGly", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10735542", "map_id": "none", "name": "GCL ligates L-Glu to L-Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174393", "map_id": "CHEBI:17515", "name": "gGluCys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735539", "map_id": "none", "name": "GCL", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94246", "map_id": "O94246", "name": "GCLM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC737.06c", "map_id": "SPCC737.06c", "name": "GCLM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09768", "map_id": "Q09768", "name": "gcs1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22F3.10c", "map_id": "SPAC22F3.10c", "name": "gcs1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735581", "map_id": "none", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735578", "map_id": "none", "name": "GSS:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P35669", "map_id": "P35669", "name": "gsa1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3F10.04", "map_id": "SPAC3F10.04", "name": "gsa1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750414", "map_id": "none", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10750411", "map_id": "none", "name": "CHAC1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P87305", "map_id": "P87305", "name": "CHAC2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC31F10.03", "map_id": "SPBC31F10.03", "name": "CHAC2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757128", "map_id": "none", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10757089", "map_id": "none", "name": "PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "P78798", "map_id": "P78798", "name": "pex7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17D4.01", "map_id": "SPAC17D4.01", "name": "pex7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757091", "map_id": "none", "name": "PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10757083", "map_id": "none", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10757067", "map_id": "none", "name": "PEX5S,L:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "O43029", "map_id": "O43029", "name": "fap1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC354.15", "map_id": "SPBC354.15", "name": "fap1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9HDX2", "map_id": "Q9HDX2", "name": "HAO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB1A11.03", "map_id": "SPAPB1A11.03", "name": "HAO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14077", "map_id": "O14077", "name": "mug138", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPACUNK4.12c", "map_id": "SPACUNK4.12c", "name": "mug138", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7N4", "map_id": "Q9Y7N4", "name": "dao1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1450.07c", "map_id": "SPCC1450.07c", "name": "dao1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7M1", "map_id": "Q9Y7M1", "name": "HACL1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC725.04", "map_id": "SPBC725.04", "name": "HACL1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13717", "map_id": "O13717", "name": "NUDT7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC14C4.10c", "map_id": "SPAC14C4.10c", "name": "NUDT7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757081", "map_id": "none", "name": "Cargo proteins containing PTS1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10757096", "map_id": "none", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10757093", "map_id": "none", "name": "PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10757085", "map_id": "none", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10757063", "map_id": "none", "name": "PEX5S,L:Cargo protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757065", "map_id": "none", "name": "PEX13:PEX14:PEX2:PEX10:PEX12", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10736821", "map_id": "none", "name": "pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736809", "map_id": "none", "name": "Btn-ACACB:2Mn2+ polymer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "P78820", "map_id": "P78820", "name": "phospho-cut6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC56E4.04c", "map_id": "SPAC56E4.04c", "name": "phospho-cut6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10736816", "map_id": "none", "name": "Btn-p-S79-ACACB:2Mn2+ polymer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10736818", "map_id": "none", "name": "AMPK heterotrimer (active)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10343", "map_id": "Q10343", "name": "cbs2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1556.08c", "map_id": "SPAC1556.08c", "name": "cbs2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78789", "map_id": "P78789", "name": "amk2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1919.03c", "map_id": "SPCC1919.03c", "name": "amk2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755610", "map_id": "none", "name": "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29508", "map_id": "CHEBI:15531", "name": "Mal-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76190", "map_id": "CHEBI:30769", "name": "CIT", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10733326", "map_id": "none", "name": "Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733323", "map_id": "none", "name": "Btn-ACACA:2Mn2+ polymer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10736829", "map_id": "none", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_201023", "map_id": "CHEBI:17126", "name": "CAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_201034", "map_id": "CHEBI:17490", "name": "L-PCARN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_549207", "map_id": "CHEBI:17126", "name": "CAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_201050", "map_id": "CHEBI:17490", "name": "L-PCARN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10736826", "map_id": "O59674", "name": "SLC25A20", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPBC29A3.11c", "map_id": "SPBC29A3.11c", "name": "SLC25A20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757932", "map_id": "none", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757928", "map_id": "none", "name": "Homologues of RND3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10757930", "map_id": "none", "name": "RND3:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10729657", "map_id": "none", "name": "UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29548", "map_id": "CHEBI:16077", "name": "G1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729654", "map_id": "none", "name": "8xUGP2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78811", "map_id": "P78811", "name": "fyu1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1322.04", "map_id": "SPCC1322.04", "name": "fyu1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729379", "map_id": "none", "name": "Mcm2-7 is phosphorylated by DDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729376", "map_id": "none", "name": "p-MCM2-7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10728818", "map_id": "none", "name": "DDK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P50582", "map_id": "P50582", "name": "hsk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC776.12c", "map_id": "SPBC776.12c", "name": "hsk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59836", "map_id": "O59836", "name": "him1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC550.13", "map_id": "SPCC550.13", "name": "him1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10728884", "map_id": "none", "name": "DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728877", "map_id": "none", "name": "CDK:DDK:MCM10:active pre-replicative complex:CDC45", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O42709", "map_id": "O42709", "name": "mcm10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1347.10", "map_id": "SPBC1347.10", "name": "mcm10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74113", "map_id": "O74113", "name": "sna41", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17D4.02", "map_id": "SPAC17D4.02", "name": "sna41", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10728792", "map_id": "none", "name": "RPA1-4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10728879", "map_id": "none", "name": "CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10728903", "map_id": "none", "name": "Cdt1 is displaced from the pre-replicative complex.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728899", "map_id": "none", "name": "MCM10:pre-replicative complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10728893", "map_id": "P40382", "name": "cdt1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728873", "map_id": "none", "name": "MCM10:active pre-replicative complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10728886", "map_id": "none", "name": "Cdc45 associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728797", "map_id": "O74113", "name": "sna41", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728875", "map_id": "none", "name": "CDK:DDK:MCM10:active pre-replicative complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10729381", "map_id": "none", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_68419", "map_id": "none", "name": "origin of replication", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728764", "map_id": "none", "name": "DNA polymerase epsilon", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10728766", "map_id": "none", "name": "DNA polymerase epsilon:origin complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10728888", "map_id": "none", "name": "CDK and DDK associate with the Mcm10:pre-replicative complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728806", "map_id": "none", "name": "CDK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10728901", "map_id": "none", "name": "Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728823", "map_id": "O42709", "name": "mcm10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10728881", "map_id": "none", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728742", "map_id": "none", "name": "DNA polymerase alpha:primase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P28040", "map_id": "P28040", "name": "pol1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3H5.06c", "map_id": "SPAC3H5.06c", "name": "pol1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14215", "map_id": "O14215", "name": "pri1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6B12.10c", "map_id": "SPAC6B12.10c", "name": "pri1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74761", "map_id": "O74761", "name": "pri2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17D11.06", "map_id": "SPBC17D11.06", "name": "pri2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74946", "map_id": "O74946", "name": "pol12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC553.09c", "map_id": "SPCC553.09c", "name": "pol12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10728768", "map_id": "none", "name": "DNA polymerase alpha:primase:DNA polymerase alpha:origin complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745090", "map_id": "none", "name": "HSF1-mediated gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745068", "map_id": "none", "name": "Heat shock inducible proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P41887", "map_id": "P41887", "name": "swo1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC926.04c", "map_id": "SPAC926.04c", "name": "swo1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745088", "map_id": "none", "name": "p-S326-HSF1 trimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10745078", "map_id": "none", "name": "p-S230-HSF1 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745122", "map_id": "none", "name": "Phosphorylation of HSF1 at Ser326 induces transactivation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745119", "map_id": "none", "name": "mTORC1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10742668", "map_id": "none", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023929", "map_id": "CHEBI:17401", "name": "IP6", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2023940", "map_id": "CHEBI:30164", "name": "5-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10742564", "map_id": "none", "name": "IP6K1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O74561", "map_id": "O74561", "name": "IP6K2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC970.08", "map_id": "SPCC970.08", "name": "IP6K2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9US14", "map_id": "Q9US14", "name": "arg82", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC607.04", "map_id": "SPAC607.04", "name": "arg82", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742651", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629765", "map_id": "CHEBI:30164", "name": "5-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629732", "map_id": "CHEBI:62923", "name": "1,5-(PP)2-IP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10742646", "map_id": "O74429", "name": "asp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC1672.06c", "map_id": "SPCC1672.06c", "name": "asp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742712", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023941", "map_id": "CHEBI:62985", "name": "5-PPP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10742814", "map_id": "none", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2023968", "map_id": "none", "name": "(PP)2-IP4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:62924", "map_id": "CHEBI:62924", "name": "CHEBI:62924", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_2023931", "map_id": "CHEBI:62923", "name": "1,5-(PP)2-IP4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_2023974", "map_id": "none", "name": "1/3-PP-IP5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:62922", "map_id": "CHEBI:62922", "name": "CHEBI:62922", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1629740", "map_id": "CHEBI:62919", "name": "1-PP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10742597", "map_id": "none", "name": "NUDT(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09790", "map_id": "Q09790", "name": "aps1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13G6.14", "map_id": "SPAC13G6.14", "name": "aps1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742641", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023901", "map_id": "CHEBI:16322", "name": "I(1,3,4,5,6)P5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2023922", "map_id": "CHEBI:62928", "name": "5-PP-IP4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10742603", "map_id": "none", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2023943", "map_id": "none", "name": "PP-IP4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_1629736", "map_id": "CHEBI:62926", "name": "1-PP-IP4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1629755", "map_id": "CHEBI:62928", "name": "5-PP-IP4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "CHEBI:62927", "map_id": "CHEBI:62927", "name": "CHEBI:62927", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_994141", "map_id": "CHEBI:16322", "name": "I(1,3,4,5,6)P5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10742591", "map_id": "none", "name": "NUDT4:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742657", "map_id": "none", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742577", "map_id": "none", "name": "IP6K1/3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742715", "map_id": "none", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629770", "map_id": "CHEBI:17401", "name": "IP6", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742580", "map_id": "none", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629759", "map_id": "CHEBI:62985", "name": "5-PPP-IP5", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742654", "map_id": "none", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629738", "map_id": "CHEBI:62931", "name": "1,5-(PP)2-IP3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742616", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10742613", "map_id": "Q9USK0", "name": "ipk1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPCC4B3.10c", "map_id": "SPCC4B3.10c", "name": "ipk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742812", "map_id": "none", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10742709", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10742718", "map_id": "none", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023948", "map_id": "CHEBI:62931", "name": "1,5-(PP)2-IP3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10742678", "map_id": "none", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10742567", "map_id": "none", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_2023932", "map_id": "CHEBI:62919", "name": "1-PP-IP5", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10742600", "map_id": "none", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10742660", "map_id": "none", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10742638", "map_id": "none", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742635", "map_id": "Q9USK0", "name": "ipk1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742608", "map_id": "none", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1629739", "map_id": "CHEBI:17816", "name": "I(1,4)P2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10741541", "map_id": "none", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1236719", "map_id": "CHEBI:16670", "name": "Exogenous soluble antigen", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_983036", "map_id": "CHEBI:25676", "name": "precursor peptide fragment (>16 aa)", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8942986", "map_id": "CHEBI:59869", "name": "L-amino acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10733749", "map_id": "none", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733734", "map_id": "none", "name": "AKT2:PIP3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10733746", "map_id": "none", "name": "p-T309,S474-AKT2:PIP3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10732851", "map_id": "none", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17940", "compartment_display": "endosome" }, { "id": "reaction_10733720", "map_id": "none", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10733716", "map_id": "Q12701", "name": "ksg1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10738628", "map_id": "none", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10738468", "map_id": "none", "name": "G-protein alpha (12/13):GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10738625", "map_id": "none", "name": "G-protein alpha (12/13):GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_111349", "map_id": "CHEBI:17552", "name": "GDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10738681", "map_id": "none", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738582", "map_id": "none", "name": "RhoA,B,C:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10738584", "map_id": "none", "name": "RHOA/B/C:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10738678", "map_id": "none", "name": "GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09763", "map_id": "Q09763", "name": "gef1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC24H6.09", "map_id": "SPAC24H6.09", "name": "gef1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59679", "map_id": "O59679", "name": "gef3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29A3.17", "map_id": "SPBC29A3.17", "name": "gef3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9HGL2", "map_id": "Q9HGL2", "name": "ITSN2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC800.10c", "map_id": "SPBC800.10c", "name": "ITSN2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USU1", "map_id": "Q9USU1", "name": "efc25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC336.03", "map_id": "SPBC336.03", "name": "efc25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P26674", "map_id": "P26674", "name": "ste6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1442.01", "map_id": "SPCC1442.01", "name": "ste6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738831", "map_id": "none", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738827", "map_id": "none", "name": "Protein kinase C, novel isoforms", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10738829", "map_id": "none", "name": "Protein kinase C, novel isoforms:DAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10734572", "map_id": "none", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10734567", "map_id": "none", "name": "PLC-beta:G-alpha(q/11):PIP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10734569", "map_id": "none", "name": "PLC-beta:G-alpha(q/11):DAG:IP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10738483", "map_id": "none", "name": "Diacylgycerol activates Protein kinase C, alpha type", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10734508", "map_id": "none", "name": "Homologues of PRKCA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10738481", "map_id": "none", "name": "Protein Kinase C, alpha type: DAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10757183", "map_id": "none", "name": "PIP3 recruits PDK1 and AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757181", "map_id": "none", "name": "PDK1:AKT:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10738633", "map_id": "none", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10738630", "map_id": "none", "name": "G-protein alpha (q/11):GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10756978", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024781", "map_id": "CHEBI:138647", "name": "4S(5)-epoxy-17(S)-HDHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024809", "map_id": "none", "name": "RvD3, RvD4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:138649", "map_id": "CHEBI:138649", "name": "CHEBI:138649", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:138648", "map_id": "CHEBI:138648", "name": "CHEBI:138648", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756976", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024602", "map_id": "CHEBI:138613", "name": "7S(8)-epoxy-17(R)-HDHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024574", "map_id": "none", "name": "AT-RvD1, AT-RvD2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:138179", "map_id": "CHEBI:138179", "name": "CHEBI:138179", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:138614", "map_id": "CHEBI:138614", "name": "CHEBI:138614", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756982", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024768", "map_id": "CHEBI:138646", "name": "7S(8)-epoxy-17(S)-HDHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024759", "map_id": "none", "name": "RvD1, RvD2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:81565", "map_id": "CHEBI:81565", "name": "CHEBI:81565", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:81564", "map_id": "CHEBI:81564", "name": "CHEBI:81564", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756984", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9024577", "map_id": "CHEBI:138612", "name": "4S(5)-epoxy-17(R)-HDHA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9024570", "map_id": "none", "name": "AT-RvD3, AT-RvD4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:138616", "map_id": "CHEBI:138616", "name": "CHEBI:138616", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:138615", "map_id": "CHEBI:138615", "name": "CHEBI:138615", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736344", "map_id": "none", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_195691", "map_id": "CHEBI:16290", "name": "CHdOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_195655", "map_id": "CHEBI:27910", "name": "7dhDESOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10736341", "map_id": "none", "name": "Homologues of SC5D", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O13666", "map_id": "O13666", "name": "erg32", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC27B12.03c", "map_id": "SPBC27B12.03c", "name": "erg32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94457", "map_id": "O94457", "name": "erg31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1687.16c", "map_id": "SPAC1687.16c", "name": "erg31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737982", "map_id": "none", "name": "phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] => phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_372364", "map_id": "CHEBI:58702", "name": "PEP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29654", "map_id": "CHEBI:30769", "name": "CIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29492", "map_id": "CHEBI:58702", "name": "PEP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10733305", "map_id": "O13844", "name": "SLC25A1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPAC19G12.05", "map_id": "SPAC19G12.05", "name": "SLC25A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729759", "map_id": "none", "name": "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_75970", "map_id": "CHEBI:57642", "name": "DHAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729756", "map_id": "none", "name": "TPI1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P07669", "map_id": "P07669", "name": "tpi1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC24B10.21", "map_id": "SPCC24B10.21", "name": "tpi1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730569", "map_id": "none", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113544", "map_id": "CHEBI:30797", "name": "MAL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10730123", "map_id": "none", "name": "MDH2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9Y7R8", "map_id": "Q9Y7R8", "name": "MDH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC306.08c", "map_id": "SPCC306.08c", "name": "MDH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729720", "map_id": "none", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729717", "map_id": "none", "name": "glucokinase and hexokinases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P50521", "map_id": "P50521", "name": "hxk2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4F8.07c", "map_id": "SPAC4F8.07c", "name": "hxk2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09756", "map_id": "Q09756", "name": "hxk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC24H6.04", "map_id": "SPAC24H6.04", "name": "hxk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10751283", "map_id": "none", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29800", "map_id": "CHEBI:57604", "name": "1,3BPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6798337", "map_id": "CHEBI:19324", "name": "2,3BPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10751280", "map_id": "none", "name": "BPGM dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P36623", "map_id": "P36623", "name": "gpm1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26F1.06", "map_id": "SPAC26F1.06", "name": "gpm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729809", "map_id": "none", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30014", "map_id": "CHEBI:32966", "name": "F1,6PP", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729806", "map_id": "none", "name": "FBP tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P09202", "map_id": "P09202", "name": "fbp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1198.14c", "map_id": "SPBC1198.14c", "name": "fbp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729793", "map_id": "none", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729788", "map_id": "none", "name": "GPI dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78917", "map_id": "P78917", "name": "pgi1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1604.05", "map_id": "SPBC1604.05", "name": "pgi1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730470", "map_id": "none", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10730467", "map_id": "none", "name": "pyruvate kinase tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10208", "map_id": "Q10208", "name": "pyk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4H3.10c", "map_id": "SPAC4H3.10c", "name": "pyk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735464", "map_id": "none", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10735462", "map_id": "none", "name": "Homologues of GCK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729703", "map_id": "none", "name": "Homologues of GCK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756422", "map_id": "none", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29728", "map_id": "CHEBI:58272", "name": "3PG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8955759", "map_id": "CHEBI:18148", "name": "G1,6BP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729642", "map_id": "none", "name": "PGM2L1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10730609", "map_id": "none", "name": "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729826", "map_id": "none", "name": "PGK complexes", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O60101", "map_id": "O60101", "name": "pgk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC14F5.04c", "map_id": "SPBC14F5.04c", "name": "pgk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729856", "map_id": "none", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30485", "map_id": "CHEBI:58289", "name": "2PG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729853", "map_id": "none", "name": "enolase dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40370", "map_id": "P40370", "name": "eno101", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1815.01", "map_id": "SPBC1815.01", "name": "eno101", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8NKC2", "map_id": "Q8NKC2", "name": "eno102", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBPB21E7.01c", "map_id": "SPBPB21E7.01c", "name": "eno102", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730452", "map_id": "none", "name": "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10730341", "map_id": "none", "name": "PGAM dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10729813", "map_id": "none", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729746", "map_id": "none", "name": "GAPDH tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O43026", "map_id": "O43026", "name": "gpd3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC354.12", "map_id": "SPBC354.12", "name": "gpd3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78958", "map_id": "P78958", "name": "tdh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC32F12.11", "map_id": "SPBC32F12.11", "name": "tdh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729781", "map_id": "none", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729778", "map_id": "none", "name": "PFK tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42938", "map_id": "O42938", "name": "pfk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16H5.02", "map_id": "SPBC16H5.02", "name": "pfk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_30533", "map_id": "CHEBI:28602", "name": "D-Fructose 2,6-bisphosphate", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10729631", "map_id": "none", "name": "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729628", "map_id": "none", "name": "phosphoPFKFB1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9URZ7", "map_id": "Q9URZ7", "name": "phospho-p-S33-PFKFB1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC732.02c", "map_id": "SPAC732.02c", "name": "phospho-p-S33-PFKFB1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729866", "map_id": "none", "name": "Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29376", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113557", "map_id": "CHEBI:15361", "name": "PYR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10729863", "map_id": "none", "name": "pyruvate carboxylase holoenzyme", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9UUE1", "map_id": "Q9UUE1", "name": "pyr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17G9.11c", "map_id": "SPBC17G9.11c", "name": "pyr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_199207", "map_id": "CHEBI:15956", "name": "Btn", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113559", "map_id": "CHEBI:57288", "name": "Ac-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10729960", "map_id": "none", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29448", "map_id": "CHEBI:29991", "name": "L-Asp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76213", "map_id": "CHEBI:30744", "name": "OA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729955", "map_id": "none", "name": "PXLP-K259-GOT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42652", "map_id": "O42652", "name": "aat2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC10F6.13c", "map_id": "SPAC10F6.13c", "name": "aat2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730605", "map_id": "none", "name": "D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10730602", "map_id": "none", "name": "PFKFB dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UTK9", "map_id": "Q9UTK9", "name": "PFKFB2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC144.17c", "map_id": "SPAC144.17c", "name": "PFKFB2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741799", "map_id": "none", "name": "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498729", "map_id": "CHEBI:28936", "name": "2-acyl LPE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1524023", "map_id": "CHEBI:16929", "name": "GPETA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10741796", "map_id": "none", "name": "Homologues of PLA2G4C", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10741812", "map_id": "none", "name": "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498738", "map_id": "CHEBI:29017", "name": "1-acyl LPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10733703", "map_id": "none", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500173", "map_id": "none", "name": "Ade-Rib, dA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17256", "map_id": "CHEBI:17256", "name": "CHEBI:17256", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500088", "map_id": "none", "name": "(d)AMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10733700", "map_id": "none", "name": "ADK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78825", "map_id": "P78825", "name": "ado1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC338.14", "map_id": "SPCC338.14", "name": "ado1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732725", "map_id": "none", "name": "APRT catalyzes the conversion of adenine to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_83951", "map_id": "CHEBI:16708", "name": "Ade", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732722", "map_id": "none", "name": "APRT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42842", "map_id": "O42842", "name": "apt1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23A1.03", "map_id": "SPAC23A1.03", "name": "apt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10733571", "map_id": "none", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29602", "map_id": "CHEBI:58053", "name": "IMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10733568", "map_id": "none", "name": "AMPD tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P50998", "map_id": "P50998", "name": "ada1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC106.04", "map_id": "SPBC106.04", "name": "ada1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734236", "map_id": "none", "name": "PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_113599", "map_id": "CHEBI:17368", "name": "Hyp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_500244", "map_id": "none", "name": "R1P, dRibP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:58576", "map_id": "CHEBI:58576", "name": "CHEBI:58576", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500172", "map_id": "none", "name": "Ino, dI", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:28997", "map_id": "CHEBI:28997", "name": "CHEBI:28997", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17596", "map_id": "CHEBI:17596", "name": "CHEBI:17596", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10732732", "map_id": "none", "name": "PNP trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UTG1", "map_id": "Q9UTG1", "name": "PNP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1805.16c", "map_id": "SPAC1805.16c", "name": "PNP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734238", "map_id": "none", "name": "PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_83956", "map_id": "CHEBI:16235", "name": "Gua", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_500245", "map_id": "none", "name": "G, dG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17172", "map_id": "CHEBI:17172", "name": "CHEBI:17172", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16750", "map_id": "CHEBI:16750", "name": "CHEBI:16750", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742023", "map_id": "none", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10741900", "map_id": "none", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500578", "map_id": "CHEBI:17984", "name": "acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10741895", "map_id": "O42916", "name": "ale1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC16A3.10", "map_id": "SPBC16A3.10", "name": "ale1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741999", "map_id": "none", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10741996", "map_id": "none", "name": "PLA2(4)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742019", "map_id": "none", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10741882", "map_id": "none", "name": "PLA2(8)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10741905", "map_id": "none", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10749926", "map_id": "none", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5694568", "map_id": "CHEBI:61232", "name": "NAPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_5694580", "map_id": "CHEBI:52571", "name": "GPAEA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_5694567", "map_id": "CHEBI:22221", "name": "acyl group", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10749923", "map_id": "O14249", "name": "ABHD4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC6G10.03c", "map_id": "SPAC6G10.03c", "name": "ABHD4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743442", "map_id": "none", "name": "METAP1/2 demethylates GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743423", "map_id": "Q04665", "name": "gpa2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10743408", "map_id": "Q04665", "name": "gpa2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10743439", "map_id": "none", "name": "METAP1/2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O60085", "map_id": "O60085", "name": "fma2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC14C8.03", "map_id": "SPBC14C8.03", "name": "fma2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59730", "map_id": "O59730", "name": "fma1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3E7.10", "map_id": "SPBC3E7.10", "name": "fma1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_880069", "map_id": "CHEBI:27638", "name": "Co2+", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10743483", "map_id": "none", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743469", "map_id": "Q09711", "name": "ncs1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "SPAC18B11.04", "map_id": "SPAC18B11.04", "name": "ncs1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743481", "map_id": "none", "name": "GUCA:Ca2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "true" }, { "id": "Q09711", "map_id": "Q09711", "name": "ncs1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743421", "map_id": "none", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2534019", "map_id": "CHEBI:15532", "name": "MYS-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10743411", "map_id": "Q04665", "name": "gpa2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_2514888", "compartment_display": "photoreceptor disc membrane", "complex": "false" }, { "id": "species_10743416", "map_id": "O43010", "name": "nmt1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC2G2.11", "map_id": "SPBC2G2.11", "name": "nmt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737739", "map_id": "none", "name": "LTA4 is hydolysed to LTB4 by LTA4H", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_265281", "map_id": "CHEBI:15651", "name": "LTA4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_266056", "map_id": "CHEBI:15647", "name": "LTB4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10737682", "map_id": "none", "name": "LTD4 is converted to LTE4 by DPEP1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_266074", "map_id": "CHEBI:28666", "name": "LTD4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_266029", "map_id": "CHEBI:57305", "name": "Gly", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_266033", "map_id": "CHEBI:15650", "name": "LTE4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10737679", "map_id": "none", "name": "DPEP1,2,3 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O59832", "map_id": "O59832", "name": "DPEP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC965.12", "map_id": "SPCC965.12", "name": "DPEP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14124", "map_id": "O14124", "name": "DPEP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737721", "map_id": "none", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_266013", "map_id": "CHEBI:16978", "name": "LTC4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10737718", "map_id": "none", "name": "GGT1, 5 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10737729", "map_id": "none", "name": "LTC4 is exported from the cytosol by ABCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_266066", "map_id": "CHEBI:16978", "name": "LTC4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737726", "map_id": "Q10185", "name": "abc2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10731420", "map_id": "none", "name": "mRNA polyadenylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10731415", "map_id": "none", "name": "3' end cleaved, ligated exon containing complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q10295", "map_id": "Q10295", "name": "pla1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.04", "map_id": "SPBC646.04", "name": "pla1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14327", "map_id": "O14327", "name": "pab2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16E9.12c", "map_id": "SPBC16E9.12c", "name": "pab2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10731327", "map_id": "Q10295", "name": "pla1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10731322", "map_id": "O14327", "name": "pab2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10730232", "map_id": "none", "name": "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_31503", "map_id": "CHEBI:15786", "name": "HTMLYS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_31311", "map_id": "CHEBI:18020", "name": "TEABL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730229", "map_id": "none", "name": "SHMT1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10104", "map_id": "Q10104", "name": "shm2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC18G6.04c", "map_id": "SPAC18G6.04c", "name": "shm2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750452", "map_id": "none", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_6787810", "map_id": "CHEBI:65101", "name": "2OH-PALM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6787814", "map_id": "CHEBI:86988", "name": "2oxo-PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10750449", "map_id": "none", "name": "HAO2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10738303", "map_id": "none", "name": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389594", "map_id": "CHEBI:15475", "name": "3S2HPhy-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389578", "map_id": "CHEBI:15522", "name": "FOR-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389636", "map_id": "CHEBI:49189", "name": "Pristanal", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10738300", "map_id": "none", "name": "HACL1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "species_29480", "map_id": "CHEBI:58937", "name": "ThDP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10756425", "map_id": "none", "name": "PRODH2 oxidises HPRO to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6784215", "map_id": "CHEBI:18240", "name": "HPRO", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113597", "map_id": "CHEBI:16238", "name": "FAD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_164934", "map_id": "CHEBI:17877", "name": "FADH2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10750340", "map_id": "O74524", "name": "PRODH2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPCC70.03c", "map_id": "SPCC70.03c", "name": "O74524", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730032", "map_id": "none", "name": "PRODH oxidises L-Pro to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10730029", "map_id": "O74524", "name": "O74524", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10740192", "map_id": "none", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10739886", "map_id": "none", "name": "Homologues of p-S221,S318-ELAVL1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9UT83", "map_id": "Q9UT83", "name": "phospho-mug28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC343.07", "map_id": "SPAC343.07", "name": "phospho-mug28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_517622", "map_id": "none", "name": "mRNA Transcript Targeted by HuR Phosphorylated on Ser221 and Ser318", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10740190", "map_id": "none", "name": "HuR with phosphoserine221 and phosphoserine318:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10739891", "map_id": "none", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10730941", "map_id": "none", "name": "Homologues of ELAVL1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10739888", "map_id": "P36583", "name": "pck2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10739874", "map_id": "none", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_450613", "map_id": "none", "name": "mRNA Transcript Targeted by HuR with Unknown Phosphorylation", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10739872", "map_id": "none", "name": "HuR with Unknown Phosphorylation: mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10739908", "map_id": "none", "name": "PKCalpha phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10739899", "map_id": "none", "name": "Homologues of p-S158,S221-ELAVL1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10739905", "map_id": "none", "name": "Homologues of PRKCA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10740188", "map_id": "none", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_450605", "map_id": "none", "name": "mRNA Transcript Targeted by HuR Phosphorylated on Ser158 and Ser318.", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10740186", "map_id": "none", "name": "HuR with phosphoserine221 and phosphoserine158:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10729539", "map_id": "none", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_68452", "map_id": "none", "name": "Okazaki fragment", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_69172", "map_id": "none", "name": "ligated okazaki fragment", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10729536", "map_id": "P12000", "name": "cdc17", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC20G8.01", "map_id": "SPAC20G8.01", "name": "cdc17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729463", "map_id": "none", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729459", "map_id": "none", "name": "PCNA homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729450", "map_id": "none", "name": "RFC Heteropentamer:RNA primer-DNA primer:origin duplex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729461", "map_id": "none", "name": "RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10729493", "map_id": "none", "name": "Formation of Processive Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729465", "map_id": "none", "name": "RNA primer-DNA primer:origin duplex:PCNA ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729489", "map_id": "none", "name": "DNA Polymerase delta tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729491", "map_id": "none", "name": "Processive complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10729502", "map_id": "none", "name": "Formation of the Flap Intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729495", "map_id": "none", "name": "Processive complex:Okazaki fragment complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729500", "map_id": "none", "name": "Processive complex:Okazaki fragment:Flap", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10729467", "map_id": "none", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10729517", "map_id": "none", "name": "Recruitment of Dna2 endonuclease", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729506", "map_id": "none", "name": "Processive complex:Okazaki fragment:Flap:RPA heterotrimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729513", "map_id": "Q9URU2", "name": "dna2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC16D10.04c", "map_id": "SPBC16D10.04c", "name": "dna2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10729515", "map_id": "none", "name": "Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9URU2", "map_id": "Q9URU2", "name": "dna2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729498", "map_id": "none", "name": "Formation of Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10729508", "map_id": "none", "name": "RPA binds to the Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10729531", "map_id": "none", "name": "Removal of remaining Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729519", "map_id": "none", "name": "Processive complex:Okazaki fragments:Remaining Flap", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10729523", "map_id": "none", "name": "Processive complex:nicked DNA from adjacent Okazaki fragments", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10729521", "map_id": "none", "name": "Removal of RNA primer and dissociation of RPA and Dna2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_418076", "map_id": "CHEBI:60377", "name": "CMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_164121", "map_id": "CHEBI:456215", "name": "AMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10729452", "map_id": "none", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729371", "map_id": "none", "name": "RNA primer-DNA primer:origin duplex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10754222", "map_id": "none", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10754218", "map_id": "O59790", "name": "ark1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC320.13c", "map_id": "SPCC320.13c", "name": "ark1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754213", "map_id": "none", "name": "SKP1:CUL1:RBX1:FBXL7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10754220", "map_id": "none", "name": "SCF-FBXL7:AURKA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O59790", "map_id": "O59790", "name": "ark1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10754274", "map_id": "none", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10754271", "map_id": "none", "name": "SCF-FBXL7:PolyUb-AURKA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10754276", "map_id": "none", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10732603", "map_id": "none", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_73871", "map_id": "CHEBI:57286", "name": "ACA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29374", "map_id": "CHEBI:57287", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_73917", "map_id": "CHEBI:15467", "name": "HMG CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10732600", "map_id": "P54874", "name": "hcs1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPAC4F8.14c", "map_id": "SPAC4F8.14c", "name": "hcs1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732595", "map_id": "none", "name": "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_73909", "map_id": "CHEBI:15344", "name": "ACA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_73911", "map_id": "CHEBI:17066", "name": "bHBA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10732592", "map_id": "none", "name": "BDH1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9URV8", "map_id": "Q9URV8", "name": "RDH5(24-318)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC106.03", "map_id": "SPBC106.03", "name": "RDH5(24-318)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9URX0", "map_id": "Q9URX0", "name": "RDH5(24-318)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736725", "map_id": "none", "name": "AKT can phosphorylate RSK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10736698", "map_id": "Q12706", "name": "psk1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10736702", "map_id": "Q12706", "name": "phospho-psk1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10736722", "map_id": "none", "name": "p-T,p-S-AKT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756118", "map_id": "none", "name": "AKT phosphorylates MKRN1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741188", "map_id": "none", "name": "Homologues of MKRN1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74463", "map_id": "O74463", "name": "MKRN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1739.01", "map_id": "SPCC1739.01", "name": "MKRN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41000", "map_id": "P41000", "name": "cps3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3A11.02", "map_id": "SPAC3A11.02", "name": "cps3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756116", "map_id": "none", "name": "Homologues of p-S109-MKRN1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10743069", "map_id": "none", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743067", "map_id": "none", "name": "PDPK1:PIP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10752710", "map_id": "none", "name": "USP13 and OTUD3 deubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10752707", "map_id": "O94526", "name": "ptn1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10750094", "map_id": "Q11119", "name": "ubp14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC6B1.06c", "map_id": "SPBC6B1.06c", "name": "ubp14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10752676", "map_id": "none", "name": "Monoubiquitinated PTEN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10752670", "map_id": "O94526", "name": "ptn1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10752674", "map_id": "O94526", "name": "ptn1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10753807", "map_id": "none", "name": "Proteasome degrades polyubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10753805", "map_id": "none", "name": "PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10753445", "map_id": "none", "name": "AKT1 dephosphorylation by PP2A-B56-beta,gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738388", "map_id": "none", "name": "Homologues of AKT1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10753440", "map_id": "none", "name": "PP2A-B56-beta,gamma", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78759", "map_id": "P78759", "name": "par2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6F12.12", "map_id": "SPAC6F12.12", "name": "par2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10752688", "map_id": "none", "name": "Deubiquitinated PTEN translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10752683", "map_id": "O94526", "name": "ptn1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10736540", "map_id": "none", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10736518", "map_id": "none", "name": "PKC-delta/epsilon", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10736537", "map_id": "none", "name": "Phospho-PKC-delta/epsilon", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10736556", "map_id": "none", "name": "AKT phosphorylates TSC2, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735151", "map_id": "Q9UUG9", "name": "tsc2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC630.13c", "map_id": "SPAC630.13c", "name": "phospho-tsc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10736554", "map_id": "Q9UUG9", "name": "phospho-tsc2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10753795", "map_id": "none", "name": "Casein kinase II phosphorylates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10753793", "map_id": "O94526", "name": "phospho-ptn1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10743403", "map_id": "none", "name": "Casein kinase II", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40232", "map_id": "P40232", "name": "ckb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1851.03", "map_id": "SPAC1851.03", "name": "ckb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P40231", "map_id": "P40231", "name": "cka1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23C11.11", "map_id": "SPAC23C11.11", "name": "cka1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756085", "map_id": "none", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10756078", "map_id": "O14109", "name": "maf1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC31G5.12c", "map_id": "SPAC31G5.12c", "name": "maf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756076", "map_id": "O14109", "name": "maf1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10752681", "map_id": "none", "name": "PTEN undergoes monoubiquitination", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10752678", "map_id": "none", "name": "XIAP,NEDD4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UTG2", "map_id": "Q9UTG2", "name": "pub2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1805.15c", "map_id": "SPAC1805.15c", "name": "pub2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q92462", "map_id": "Q92462", "name": "pub1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC11G7.02", "map_id": "SPAC11G7.02", "name": "pub1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14326", "map_id": "O14326", "name": "pub3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16E9.11c", "map_id": "SPBC16E9.11c", "name": "pub3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736552", "map_id": "none", "name": "AKT phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736545", "map_id": "O74503", "name": "spp27", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736549", "map_id": "O74503", "name": "phospho-spp27", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10756121", "map_id": "none", "name": "MKRN1 polyubiquitinates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10752686", "map_id": "none", "name": "USP7 deubiquitinates monoubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747825", "map_id": "Q09879", "name": "ubp5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10752704", "map_id": "none", "name": "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10752691", "map_id": "O94526", "name": "ptn1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10752701", "map_id": "none", "name": "NEDD4,STUB1,WWP2 and XIAP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757421", "map_id": "none", "name": "ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744302", "map_id": "none", "name": "p-T185,Y187 MAPK1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10736630", "map_id": "none", "name": "p-Y185,Y187 MAPK1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10757419", "map_id": "none", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10757406", "map_id": "none", "name": "PDPK1:PIP3:p-T410-PRKCZ", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10757416", "map_id": "none", "name": "PDPK1:PIP3:pS, p-T410 PRKCZ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10744869", "map_id": "none", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744858", "map_id": "Q9P7S7", "name": "nop58", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC23G3.06", "map_id": "SPAC23G3.06", "name": "nop58", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744867", "map_id": "none", "name": "2SUMO1:NOP58", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9P7S7", "map_id": "Q9P7S7", "name": "nop58", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744879", "map_id": "none", "name": "RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10730960", "map_id": "Q10145", "name": "HNRNPC", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC3H8.09c", "map_id": "SPAC3H8.09c", "name": "SUMO1-K250-HNRNPC", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744877", "map_id": "none", "name": "SUMO1:HNRNPC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q10145", "map_id": "Q10145", "name": "SUMO1-K250-HNRNPC", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738944", "map_id": "none", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_77087", "map_id": "CHEBI:15414", "name": "AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10737547", "map_id": "none", "name": "Chromatin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_77502", "map_id": "CHEBI:16680", "name": "AdoHcy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10732938", "map_id": "none", "name": "Chromatin (H3K9me2)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10738938", "map_id": "none", "name": "eNoSC", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O94640", "map_id": "O94640", "name": "sir2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16D10.07c", "map_id": "SPBC16D10.07c", "name": "sir2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10257", "map_id": "Q10257", "name": "rrp8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC56F8.09", "map_id": "SPAC56F8.09", "name": "rrp8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738941", "map_id": "none", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10738924", "map_id": "none", "name": "Chromatin with acetylated H3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_427523", "map_id": "CHEBI:57540", "name": "NAD+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_427498", "map_id": "CHEBI:76279", "name": "2'-O-acetyl-ADP-ribose", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_427497", "map_id": "CHEBI:17154", "name": "NAM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10735753", "map_id": "none", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10735739", "map_id": "O94329", "name": "psf2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC725.13c", "map_id": "SPBC725.13c", "name": "psf2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735734", "map_id": "Q9P7X6", "name": "psf1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBP23A10.09", "map_id": "SPBP23A10.09", "name": "psf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735749", "map_id": "Q9P7C8", "name": "sld5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBP4H10.21c", "map_id": "SPBP4H10.21c", "name": "sld5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735744", "map_id": "Q9UTC3", "name": "psf3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC227.16c", "map_id": "SPAC227.16c", "name": "psf3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735751", "map_id": "none", "name": "GINS complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9UTC3", "map_id": "Q9UTC3", "name": "psf3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94329", "map_id": "O94329", "name": "psf2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7X6", "map_id": "Q9P7X6", "name": "psf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7C8", "map_id": "Q9P7C8", "name": "sld5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10733255", "map_id": "none", "name": "Phosphorylation of Cdc25C at Ser216 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10732945", "map_id": "P06652", "name": "cdc25", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10732948", "map_id": "P06652", "name": "phospho-cdc25", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10729617", "map_id": "Q10292", "name": "phospho-mek1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC14C4.03", "map_id": "SPAC14C4.03", "name": "phospho-mek1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757028", "map_id": "none", "name": "p-S216-CDC25C translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10732952", "map_id": "P06652", "name": "phospho-cdc25", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10752429", "map_id": "none", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10752417", "map_id": "none", "name": "Ficolin-rich granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800405", "compartment_display": "ficolin-1-rich granule lumen", "complex": "true" }, { "id": "O13808", "map_id": "O13808", "name": "gmf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17H9.11", "map_id": "SPAC17H9.11", "name": "gmf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13370", "map_id": "O13370", "name": "ded1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1795.11", "map_id": "SPCC1795.11", "name": "ded1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10316", "map_id": "Q10316", "name": "arc5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17G8.04c", "map_id": "SPAC17G8.04c", "name": "arc5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87057", "map_id": "P87057", "name": "nhp6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P0CT53", "map_id": "P0CT53", "name": "tef101", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC794.09c", "map_id": "SPCC794.09c", "name": "tef101", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13834", "map_id": "O13834", "name": "ptr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC19D5.04", "map_id": "SPAC19D5.04", "name": "ptr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7Q8", "map_id": "Q9P7Q8", "name": "pmo25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1834.06c", "map_id": "SPAC1834.06c", "name": "pmo25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14098", "map_id": "O14098", "name": "lsk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2F3.15", "map_id": "SPAC2F3.15", "name": "lsk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14256", "map_id": "O14256", "name": "MMTAG2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6G10.10c", "map_id": "SPAC6G10.10c", "name": "MMTAG2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78974", "map_id": "P78974", "name": "hem2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1805.06c", "map_id": "SPAC1805.06c", "name": "hem2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09190", "map_id": "Q09190", "name": "pcd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1556.04c", "map_id": "SPAC1556.04c", "name": "pcd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94395", "map_id": "O94395", "name": "pku70", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC126.02c", "map_id": "SPCC126.02c", "name": "pku70", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUJ1", "map_id": "Q9UUJ1", "name": "arp2", "type": "complex_component", "sub_type": 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"inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1827.08c", "map_id": "SPCC1827.08c", "name": "pof7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10435", "map_id": "Q10435", "name": "TRIP12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC12B10.01c", "map_id": "SPAC12B10.01c", "name": "TRIP12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UTL5", "map_id": "Q9UTL5", "name": "sfc2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC144.09c", "map_id": "SPAC144.09c", "name": "sfc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94264", "map_id": "O94264", "name": "RBBP6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP8B7.15c", "map_id": "SPBP8B7.15c", "name": "RBBP6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P4W7", "map_id": "Q9P4W7", "name": "apc5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC959.09c", "map_id": "SPAC959.09c", "name": "apc5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74855", "map_id": "O74855", "name": "rsa4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": 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"sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741312", "map_id": "none", "name": "Ubiquitin:E2 conjugating enzymes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P7R4", "map_id": "Q9P7R4", "name": "ubc8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC211.07c", "map_id": "SPBC211.07c", "name": "ubc8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94609", "map_id": "O94609", "name": "ptr3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1604.21c", "map_id": "SPBC1604.21c", "name": "ptr3", "type": 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"inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC10F6.05c", "map_id": "SPAC10F6.05c", "name": "ubc6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74549", "map_id": "O74549", "name": "ubc12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC777.10c", "map_id": "SPCC777.10c", "name": "ubc12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O00102", "map_id": "O00102", "name": "ubc7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP16F5.04", "map_id": "SPBP16F5.04", "name": "ubc7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74810", "map_id": "O74810", "name": "ubc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2D10.20", "map_id": "SPBC2D10.20", "name": "ubc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741349", "map_id": "none", "name": "E3:K48-polyubiquitinated substrate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10741310", "map_id": "none", "name": "E2 Ubiquitin-conjugating enzyme", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10752530", "map_id": "none", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_166005", "map_id": "CHEBI:16412", "name": "LPS", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10752528", "map_id": "none", "name": "HC23,45-HMGB1:LPS", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10742867", "map_id": "none", "name": "RAC1 and CDC42 activate PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738332", "map_id": "none", "name": "PAK1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10742858", "map_id": "none", "name": "RAC1:GTP,CDC42:GTP:PAK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10738330", "map_id": "P50527", "name": "shk1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10752267", "map_id": "none", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6800424", "compartment_display": "ficolin-1-rich granule membrane" }, { "id": "species_10752257", "map_id": "none", "name": "Ficolin-rich granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800424", "compartment_display": "ficolin-1-rich granule membrane", "complex": "true" }, { "id": "Q9UUF7", "map_id": "Q9UUF7", "name": "sec26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC146.14c", "map_id": "SPBC146.14c", "name": "sec26", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P3W4", "map_id": "Q9P3W4", "name": "dil1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC458.04c", "map_id": "SPAC458.04c", "name": "dil1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7J5", "map_id": "Q9Y7J5", "name": "TBC1D10A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1778.09", "map_id": "SPBC1778.09", "name": "TBC1D10A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9C0Y4", "map_id": "Q9C0Y4", "name": "agl1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB24D3.10c", "map_id": "SPAPB24D3.10c", "name": "agl1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9URX4", "map_id": "Q9URX4", "name": "GAA (204-?)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC30D11.01c", "map_id": "SPAC30D11.01c", "name": "GAA (204-?)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09901", "map_id": "Q09901", "name": "GAA (204-?)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UR05", "map_id": "Q9UR05", "name": "dlc2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC926.07c", "map_id": "SPAC926.07c", "name": "dlc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10752265", "map_id": "none", "name": "Ficolin-rich granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10743526", "map_id": "none", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6800173", "compartment_display": "tertiary granule lumen" }, { "id": "species_10751567", "map_id": "none", "name": "Tertiary granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6800173", "compartment_display": "tertiary granule lumen", "complex": "true" }, { "id": "Q10182", "map_id": "Q10182", "name": "erf4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3F10.07c", "map_id": "SPAC3F10.07c", "name": "erf4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13728", "map_id": "O13728", "name": "ain1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC15A10.08", "map_id": "SPAC15A10.08", "name": "ain1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13986", "map_id": "O13986", "name": "ARMC8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26H5.04", "map_id": "SPAC26H5.04", "name": "ARMC8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10166", "map_id": "Q10166", "name": "NIT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26A3.11", "map_id": "SPAC26A3.11", "name": "NIT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10751589", "map_id": "none", "name": "Tertiary granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10741390", "map_id": "none", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_983034", "map_id": "CHEBI:25676", "name": "oligopeptide fragment", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_983033", "map_id": "CHEBI:25676", "name": "Antigen peptide", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_8943716", "map_id": "CHEBI:59869", "name": "L-amino acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10741385", "map_id": "Q9USX1", "name": "ape1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "SPBC1921.05", "map_id": "SPBC1921.05", "name": "ape1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737119", "map_id": "none", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10737116", "map_id": "none", "name": "Active PKC theta bound to DAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10737090", "map_id": "none", "name": "PDK1:PIP2,PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10751415", "map_id": "none", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6798757", "compartment_display": "azurophil granule membrane" }, { "id": "species_10751383", "map_id": "none", "name": "Azurophil granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6798757", "compartment_display": "azurophil granule membrane", "complex": "true" }, { "id": "O59866", "map_id": "O59866", "name": "wbp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC338.15", "map_id": "SPCC338.15", "name": "wbp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60119", "map_id": "O60119", "name": "scs2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16G5.05c", "map_id": "SPBC16G5.05c", "name": "scs2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USS6", "map_id": "Q9USS6", "name": "ACPP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4.06", "map_id": "SPBC4.06", "name": "ACPP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8TFH3", "map_id": "Q8TFH3", "name": "ost3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74559", "map_id": "O74559", "name": "SURF4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC970.06", "map_id": "SPCC970.06", "name": "SURF4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10751413", "map_id": "none", "name": "Azurophil granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10741351", "map_id": "none", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983123", "map_id": "none", "name": "K48polyUb-antigenic substrate", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10741221", "map_id": "none", "name": "E3 ligases in proteasomal degradation", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10743820", "map_id": "none", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_874088", "map_id": "CHEBI:16991", "name": "Double-stranded DNA", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10743816", "map_id": "Q09683", "name": "rad32", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10743818", "map_id": "none", "name": "MRE11:dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10745986", "map_id": "none", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10745398", "map_id": "P36583", "name": "phospho-pck2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745984", "map_id": "none", "name": "DAGs:p-T507,S645,S664-PRKCD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10757837", "map_id": "none", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757816", "map_id": "none", "name": "Homologues of FKBP1A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10175", "map_id": "Q10175", "name": "FKBP1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27F1.06c", "map_id": "SPAC27F1.06c", "name": "FKBP1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42993", "map_id": "O42993", "name": "fkh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC839.17c", "map_id": "SPBC839.17c", "name": "fkh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_9678991", "map_id": "LigandDisplayForward?ligandId=6784", "name": "tacrolimus", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10757835", "map_id": "none", "name": "FKBP1A:tacrolimus", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10741380", "map_id": "none", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983035", "map_id": "none", "name": "antigenic substrate", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10741314", "map_id": "none", "name": "Ag-substrate:E3:E2:Ub", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10751953", "map_id": "none", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen" }, { "id": "species_10751817", "map_id": "none", "name": "Secretory granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1462052", "compartment_display": "secretory granule lumen", "complex": "true" }, { "id": "Q9HGM8", "map_id": "Q9HGM8", "name": "pku80", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC543.03c", "map_id": "SPBC543.03c", "name": "pku80", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14242", "map_id": "O14242", "name": "PDXK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6F6.11c", "map_id": "SPAC6F6.11c", "name": "PDXK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74335", "map_id": "O74335", "name": "rga5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17F3.01c", "map_id": "SPBC17F3.01c", "name": "rga5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94466", "map_id": "O94466", "name": "rga7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC23G7.08c", "map_id": "SPBC23G7.08c", "name": "rga7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10305", "map_id": "Q10305", "name": "gdi1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22H10.12c", "map_id": "SPAC22H10.12c", "name": "gdi1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10751951", "map_id": "none", "name": "Secretory granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10738399", "map_id": "none", "name": "Dephosphorylation of AKT by PP2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738274", "map_id": "none", "name": "PP2A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10741612", "map_id": "none", "name": "Activation of p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741601", "map_id": "none", "name": "p38 MAPK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10741609", "map_id": "none", "name": "Phospho-p38 MAPK", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10739738", "map_id": "none", "name": "Homologues of p-S207,T211-MAP2K6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10741353", "map_id": "none", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_983032", "map_id": "CHEBI:25676", "name": "oligopeptide fragment (8-16aa)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742956", "map_id": "none", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_2213225", "map_id": "none", "name": "unfolded antigen", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_2213226", "map_id": "none", "name": "MHC class II epitopes", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10742951", "map_id": "P32834", "name": "sxa1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "reaction_10751977", "map_id": "none", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799371", "compartment_display": "specific granule lumen" }, { "id": "species_10751969", "map_id": "none", "name": "Specific granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799371", "compartment_display": "specific granule lumen", "complex": "true" }, { "id": "Q10066", "map_id": "Q10066", "name": "aru1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3H1.07", "map_id": "SPAC3H1.07", "name": "aru1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10751975", "map_id": "none", "name": "Specific granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10751653", "map_id": "none", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6799713", "compartment_display": "tertiary granule membrane" }, { "id": "species_10751641", "map_id": "none", "name": "Tertiary granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6799713", "compartment_display": "tertiary granule membrane", "complex": "true" }, { "id": "species_10751651", "map_id": "none", "name": "Tertiary granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10745990", "map_id": "none", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10745988", "map_id": "none", "name": "DAGs:active p-T507,S645,S664-PRKCD", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10741530", "map_id": "none", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane" }, { "id": "species_1470067", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_1222282", "compartment_display": "phagocytic vesicle lumen", "complex": "false" }, { "id": "species_10741527", "map_id": "none", "name": "V-ATPase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10741321", "map_id": "none", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10740329", "map_id": "none", "name": "SGT1 binds HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740325", "map_id": "P41887", "name": "swo1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740323", "map_id": "O59709", "name": "git7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC36.12c", "map_id": "SPBC36.12c", "name": "git7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740327", "map_id": "none", "name": "SUGT1:HSP90", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O59709", "map_id": "O59709", "name": "git7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741337", "map_id": "none", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10741334", "map_id": "none", "name": "TAP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10742881", "map_id": "none", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_264618", "map_id": "CHEBI:15354", "name": "Cho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1602448", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10742876", "map_id": "Q09706", "name": "pld1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10737092", "map_id": "none", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_202277", "map_id": "none", "name": "PIP3, PI(3,4)P2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10752099", "map_id": "none", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1470028", "compartment_display": "azurophil granule lumen" }, { "id": "species_10752055", "map_id": "none", "name": "Azurophil granule lumen proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1470028", "compartment_display": "azurophil granule lumen", "complex": "true" }, { "id": "Q9UT70", "map_id": "Q9UT70", "name": "bet5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3G9.16c", "map_id": "SPAC3G9.16c", "name": "bet5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74557", "map_id": "O74557", "name": "cbr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC970.03", "map_id": "SPCC970.03", "name": "cbr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74492", "map_id": "O74492", "name": "TTR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC285.04", "map_id": "SPCC285.04", "name": "TTR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9URZ0", "map_id": "Q9URZ0", "name": "mel1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC869.07c", "map_id": "SPAC869.07c", "name": "mel1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74498", "map_id": "O74498", "name": "ucp10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC285.11", "map_id": "SPCC285.11", "name": "ucp10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P36621", "map_id": "P36621", "name": "cap1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC306.09c", "map_id": "SPCC306.09c", "name": "cap1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P15258", "map_id": "P15258", "name": "ral2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC21.05c", "map_id": "SPBC21.05c", "name": "ral2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10147", "map_id": "Q10147", "name": "cct2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1D4.04", "map_id": "SPAC1D4.04", "name": "cct2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13290", "map_id": "O13290", "name": "dhc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1093.06c", "map_id": "SPAC1093.06c", "name": "dhc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09184", "map_id": "Q09184", "name": "cdb4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23H4.09", "map_id": "SPAC23H4.09", "name": "cdb4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUB5", "map_id": "Q9UUB5", "name": "mis13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC409.09c", "map_id": "SPBC409.09c", "name": "mis13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10752097", "map_id": "none", "name": "Azurophil granule lumen proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10741648", "map_id": "none", "name": "TXNIP binds reduced thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741644", "map_id": "none", "name": "Homologues of TXNIP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09889", "map_id": "Q09889", "name": "TXNIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC584.15c", "map_id": "SPCC584.15c", "name": "TXNIP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60150", "map_id": "O60150", "name": "TXNIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8WZK5", "map_id": "Q8WZK5", "name": "TXNIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10347", "map_id": "Q10347", "name": "TXNIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09729", "map_id": "Q09729", "name": "TXNIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74798", "map_id": "O74798", "name": "TXNIP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741646", "map_id": "none", "name": "Thioredoxin:TXNIP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742887", "map_id": "none", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737182", "map_id": "none", "name": "G-actin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10742885", "map_id": "none", "name": "Mother filament:ARP2/3:actin:ADP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78774", "map_id": "P78774", "name": "arc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC14C8.06", "map_id": "SPBC14C8.06", "name": "arc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q92352", "map_id": "Q92352", "name": "arc4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6G9.07c", "map_id": "SPAC6G9.07c", "name": "arc4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14241", "map_id": "O14241", "name": "arc2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6F6.10c", "map_id": "SPAC6F6.10c", "name": "arc2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P32390", "map_id": "P32390", "name": "act2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC630.03", "map_id": "SPAC630.03", "name": "act2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7J4", "map_id": "Q9Y7J4", "name": "arc3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1778.08c", "map_id": "SPBC1778.08c", "name": "arc3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10742765", "map_id": "none", "name": "Mother filament:branching complex:daughter filament", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742865", "map_id": "none", "name": "Autophosphorylation of PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742862", "map_id": "P50527", "name": "phospho-shk1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10741375", "map_id": "none", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741367", "map_id": "none", "name": "Ubiquitin activating E1 enzymes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09765", "map_id": "Q09765", "name": "uba3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC24H6.12c", "map_id": "SPAC24H6.12c", "name": "uba3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741369", "map_id": "none", "name": "E1 bound ubiquitin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10738619", "map_id": "none", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_202124", "map_id": "CHEBI:16480", "name": "NO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29968", "map_id": "CHEBI:16349", "name": "L-Cit", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10738616", "map_id": "none", "name": "NOS1,2,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10743556", "map_id": "none", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743536", "map_id": "none", "name": "NFAT:CaN:CaM", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10743554", "map_id": "none", "name": "NFAT:CaN:CaM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10737443", "map_id": "none", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10737349", "map_id": "none", "name": "SAR1B:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q01475", "map_id": "Q01475", "name": "sar1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC31F10.06c", "map_id": "SPBC31F10.06c", "name": "sar1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10737439", "map_id": "none", "name": "SEC23:SEC24", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74873", "map_id": "O74873", "name": "sec231", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC31H12.07", "map_id": "SPCC31H12.07", "name": "sec231", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUI5", "map_id": "Q9UUI5", "name": "sec24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22F8.08", "map_id": "SPAC22F8.08", "name": "sec24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USS7", "map_id": "Q9USS7", "name": "SEC24D", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4.03c", "map_id": "SPBC4.03c", "name": "SEC24D", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10737441", "map_id": "none", "name": "SAR1B:GTP:SEC23:SEC24", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10741491", "map_id": "none", "name": "PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734514", "map_id": "none", "name": "Homologues of PRKCB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_33625", "map_id": "CHEBI:18303", "name": "PS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10734538", "map_id": "none", "name": "Activated PKC beta", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10751533", "map_id": "none", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10751485", "map_id": "none", "name": "Secretory granule membrane proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "true" }, { "id": "Q10201", "map_id": "Q10201", "name": "IQGAP3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17D1.07c", "map_id": "SPBC17D1.07c", "name": "IQGAP3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9HDY0", "map_id": "Q9HDY0", "name": "ypt71", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB1A10.10c", "map_id": "SPAPB1A10.10c", "name": "ypt71", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P17608", "map_id": "P17608", "name": "ryh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4C5.02c", "map_id": "SPAC4C5.02c", "name": "ryh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94655", "map_id": "O94655", "name": "ypt7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC405.04c", "map_id": "SPBC405.04c", "name": "ypt7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USX1", "map_id": "Q9USX1", "name": "ape1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14188", "map_id": "O14188", "name": "rng2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4F8.13c", "map_id": "SPAC4F8.13c", "name": "rng2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10751531", "map_id": "none", "name": "Secretory granule membrane proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10742874", "map_id": "none", "name": "Conversion of PA into DAG by PAP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10742869", "map_id": "Q9UUA6", "name": "dpp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10737129", "map_id": "none", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736928", "map_id": "none", "name": "Homologues of PRKCQ", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737127", "map_id": "none", "name": "PKC-theta (open): DAG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10741395", "map_id": "none", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741392", "map_id": "Q9USX1", "name": "ape1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10741372", "map_id": "none", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10745417", "map_id": "none", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10745410", "map_id": "none", "name": "p-PKC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10745415", "map_id": "none", "name": "DAG:active PKC:Ca+2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10737056", "map_id": "none", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737053", "map_id": "none", "name": "p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_29870", "map_id": "CHEBI:15372", "name": "BH4", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_5693375", "map_id": "CHEBI:25682", "name": "ADMA", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10737080", "map_id": "none", "name": "AKT1 binds eNOS complex via HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737016", "map_id": "none", "name": "eNOS:CaM:HSP90", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10737024", "map_id": "none", "name": "eNOS:CaM:HSP90:p-AKT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10745428", "map_id": "none", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10745425", "map_id": "none", "name": "PKCA,PKCB,PKCD,PKCZ", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10745378", "map_id": "none", "name": "p-PKCA,p-PKCB,p-PKCZ,p-PKCD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10737051", "map_id": "none", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737049", "map_id": "none", "name": "p-S1177-eNOS:CaM:HSP90:p-AKT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10742175", "map_id": "none", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10745434", "map_id": "none", "name": "PKC phosphorylates sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10738404", "map_id": "O14159", "name": "lcb4", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC4A8.07c", "map_id": "SPAC4A8.07c", "name": "lcb4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745431", "map_id": "O14159", "name": "phospho-lcb4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10745413", "map_id": "none", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10756127", "map_id": "none", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10735134", "map_id": "none", "name": "F1Fo ATP synthase", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P21535", "map_id": "P21535", "name": "atp6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPMIT.07", "map_id": "SPMIT.07", "name": "atp6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74999", "map_id": "O74999", "name": "rhp7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC330.02", "map_id": "SPCC330.02", "name": "rhp7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22068", "map_id": "P22068", "name": "atp2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC222.12c", "map_id": "SPAC222.12c", "name": "atp2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87316", "map_id": "P87316", "name": "atp15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC31F10.15c", "map_id": "SPBC31F10.15c", "name": "atp15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09774", "map_id": "Q09774", "name": "atp20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22F3.07c", "map_id": "SPAC22F3.07c", "name": "atp20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94390", "map_id": "O94390", "name": "atp7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29A10.13", "map_id": "SPBC29A10.13", "name": "atp7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P6R6", "map_id": "Q9P6R6", "name": "atp16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC13E7.04", "map_id": "SPBC13E7.04", "name": "atp16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74479", "map_id": "O74479", "name": "atp5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1840.06", "map_id": "SPCC1840.06", "name": "atp5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P21537", "map_id": "P21537", "name": "atp9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPMIT.10", "map_id": "SPMIT.10", "name": "atp9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74754", "map_id": "O74754", "name": "atp3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1734.13", "map_id": "SPBC1734.13", "name": "atp3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P24487", "map_id": "P24487", "name": "atp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC14C4.14", "map_id": "SPAC14C4.14", "name": "atp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94373", "map_id": "O94373", "name": "atp4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1604.07", "map_id": "SPBC1604.07", "name": "atp4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74783", "map_id": "O74783", "name": "pof2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC25B2.11", "map_id": "SPBC25B2.11", "name": "pof2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756125", "map_id": "none", "name": "F1Fo ATP synthase dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10743814", "map_id": "none", "name": "SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743242", "map_id": "none", "name": "Cohesin Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q92380", "map_id": "Q92380", "name": "rec11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC4E9.01c", "map_id": "SPCC4E9.01c", "name": "rec11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42649", "map_id": "O42649", "name": "psm3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC10F6.09c", "map_id": "SPAC10F6.09c", "name": "psm3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13816", "map_id": "O13816", "name": "phospho-psc3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17H9.20", "map_id": "SPAC17H9.20", "name": "phospho-psc3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P30776", "map_id": "P30776", "name": "phospho-rad21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC338.17c", "map_id": "SPCC338.17c", "name": "phospho-rad21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94383", "map_id": "O94383", "name": "psm1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29A10.04", "map_id": "SPBC29A10.04", "name": "psm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743780", "map_id": "none", "name": "SUMOylated Cohesin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10743811", "map_id": "none", "name": "SMC5-SMC6 Complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P53692", "map_id": "P53692", "name": "smc6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC5E4.06", "map_id": "SPCC5E4.06", "name": "smc6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13710", "map_id": "O13710", "name": "smc5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC14C4.02c", "map_id": "SPAC14C4.02c", "name": "smc5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q6BDR8", "map_id": "Q6BDR8", "name": "nse4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC20F10.04c", "map_id": "SPBC20F10.04c", "name": "nse4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q4PIR3", "map_id": "Q4PIR3", "name": "nse2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC16A10.06c", "map_id": "SPAC16A10.06c", "name": "nse2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7U4", "map_id": "Q9Y7U4", "name": "nse3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC645.04", "map_id": "SPCC645.04", "name": "nse3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q53EK2", "map_id": "Q53EK2", "name": "nse1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC550.05", "map_id": "SPCC550.05", "name": "nse1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744821", "map_id": "none", "name": "SUMOylation of TDG with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733857", "map_id": "O59825", "name": "thp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPCC965.05c", "map_id": "SPCC965.05c", "name": "thp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744819", "map_id": "none", "name": "SUMO1:TDG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O59825", "map_id": "O59825", "name": "thp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744848", "map_id": "none", "name": "SUMOylation of RAD52 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744846", "map_id": "none", "name": "3SUMO1:RAD52", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10744919", "map_id": "none", "name": "SUMOylation of MDC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744909", "map_id": "O14079", "name": "mdb1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPACUNK4.14", "map_id": "SPACUNK4.14", "name": "mdb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744917", "map_id": "none", "name": "SUMO1:MDC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O14079", "map_id": "O14079", "name": "mdb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744904", "map_id": "none", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744894", "map_id": "P87235", "name": "rhp42", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPCC4G3.10c", "map_id": "SPCC4G3.10c", "name": "rhp42", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744902", "map_id": "none", "name": "SUMO1:XPC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P87235", "map_id": "P87235", "name": "rhp42", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730240", "map_id": "none", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30401", "map_id": "CHEBI:16344", "name": "GAA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29916", "map_id": "CHEBI:16919", "name": "CRET", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730237", "map_id": "Q10170", "name": "rmt2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC26A3.17c", "map_id": "SPAC26A3.17c", "name": "rmt2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753723", "map_id": "none", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8848577", "map_id": "CHEBI:16125", "name": "HXOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8848499", "map_id": "CHEBI:75584", "name": "PALM-PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10749964", "map_id": "O74850", "name": "dga1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPCC1235.15", "map_id": "SPCC1235.15", "name": "dga1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753726", "map_id": "none", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_30209", "map_id": "CHEBI:17336", "name": "atROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2534407", "map_id": "CHEBI:17616", "name": "atR-PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10749962", "map_id": "none", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5696426", "map_id": "CHEBI:75627", "name": "ARACOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_192172", "map_id": "CHEBI:17984", "name": "Acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_162743", "map_id": "CHEBI:57287", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_5696412", "map_id": "CHEBI:10036", "name": "arachidyl ester", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen", "complex": "false" }, { "id": "species_10749959", "map_id": "O74850", "name": "dga1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10734474", "map_id": "none", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113656", "map_id": "none", "name": "RNA primer-DNA primer:origin duplex with DNA damage", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10756722", "map_id": "none", "name": "RHOB binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756718", "map_id": "none", "name": "RHOB effectors (plasma membrane)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78953", "map_id": "P78953", "name": "mid1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC4B3.15", "map_id": "SPCC4B3.15", "name": "mid1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43027", "map_id": "O43027", "name": "rga6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC354.13", "map_id": "SPBC354.13", "name": "rga6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P3B1", "map_id": "Q9P3B1", "name": "ARHGAP8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1565.02c", "map_id": "SPAC1565.02c", "name": "ARHGAP8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756713", "map_id": "none", "name": "RHOB:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10756720", "map_id": "none", "name": "RHOB:GTP:cytosolic RHOB effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10756711", "map_id": "none", "name": "GDIs block activation of RHOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756705", "map_id": "O14224", "name": "ARHGDIG", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC6F12.06", "map_id": "SPAC6F12.06", "name": "ARHGDIG", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756703", "map_id": "none", "name": "RHOB:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10756709", "map_id": "none", "name": "RHOB:GDP:RHOB GDIs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14224", "map_id": "O14224", "name": "ARHGDIG", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756716", "map_id": "none", "name": "RHOB GAPs stimulate RHOB GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756508", "map_id": "none", "name": "Homologues of ARHGAP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757839", "map_id": "none", "name": "RHOB translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10746731", "map_id": "none", "name": "RHOB:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10737802", "map_id": "none", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_351164", "map_id": "CHEBI:17431", "name": "AGM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737799", "map_id": "Q9UQW9", "name": "spe1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC144.04c", "map_id": "SPAC144.04c", "name": "spe1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740399", "map_id": "none", "name": "PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_916850", "map_id": "CHEBI:59888", "name": "GABA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_880046", "map_id": "CHEBI:57706", "name": "SUCCSA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10740396", "map_id": "none", "name": "PXLP-K357-ABAT dimer:2Fe-2S", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:33739", "map_id": "CHEBI:33739", "name": "CHEBI:33739", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13837", "map_id": "O13837", "name": "uga1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC19D5.07", "map_id": "SPAC19D5.07", "name": "uga1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740363", "map_id": "none", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113536", "map_id": "CHEBI:30031", "name": "SUCCA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10740360", "map_id": "none", "name": "ALDH5A1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9US47", "map_id": "Q9US47", "name": "ALDH5A1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1002.12c", "map_id": "SPAC1002.12c", "name": "ALDH5A1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735650", "map_id": "none", "name": "Recruitment of DNA2 endonuclease to the C strand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10735624", "map_id": "none", "name": "Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O14246", "map_id": "O14246", "name": "tpz1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6F6.16c", "map_id": "SPAC6F6.16c", "name": "tpz1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q96TL7", "map_id": "Q96TL7", "name": "rap1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1778.02", "map_id": "SPBC1778.02", "name": "rap1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:15986", "map_id": "CHEBI:15986", "name": "CHEBI:15986", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13988", "map_id": "O13988", "name": "pot1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26H5.06", "map_id": "SPAC26H5.06", "name": "pot1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735626", "map_id": "none", "name": "Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10732942", "map_id": "none", "name": "Elongation of pre-rRNA transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_350", "compartment_display": "nucleolus" }, { "id": "species_9757634", "map_id": "CHEBI:61557", "name": "NTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_74985", "map_id": "none", "name": "elongating pre-rRNA transcript", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10732500", "map_id": "none", "name": "RNA Polymerase I promoter escape complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O94703", "map_id": "O94703", "name": "rpa12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1259.03", "map_id": "SPCC1259.03", "name": "rpa12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14086", "map_id": "O14086", "name": "rpa49", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2F3.03c", "map_id": "SPAC2F3.03c", "name": "rpa49", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UST5", "map_id": "Q9UST5", "name": "rrn7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC336.09c", "map_id": "SPBC336.09c", "name": "rrn7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P15398", "map_id": "P15398", "name": "rpa1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4C3.05c", "map_id": "SPBC4C3.05c", "name": "rpa1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7X8", "map_id": "Q9P7X8", "name": "rpa2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP23A10.07", "map_id": "SPBP23A10.07", "name": "rpa2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43036", "map_id": "O43036", "name": "rpa43", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B9.07c", "map_id": "SPBC3B9.07c", "name": "rpa43", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10732940", "map_id": "none", "name": "Chromatin (H3K9me2):CBX3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P40381", "map_id": "P40381", "name": "swi6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC664.01c", "map_id": "SPAC664.01c", "name": "swi6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10103", "map_id": "Q10103", "name": "chp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC18G6.02c", "map_id": "SPAC18G6.02c", "name": "chp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42934", "map_id": "O42934", "name": "chp2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16C6.10", "map_id": "SPBC16C6.10", "name": "chp2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732415", "map_id": "none", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10732406", "map_id": "none", "name": "RNA Polymerase I Holoenzyme", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10732411", "map_id": "Q10110", "name": "rrn3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC18G6.11c", "map_id": "SPAC18G6.11c", "name": "rrn3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10732413", "map_id": "none", "name": "Active RNA Polymerase I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q10110", "map_id": "Q10110", "name": "rrn3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732502", "map_id": "none", "name": "Loss of Rrn3 from RNA Polymerase I promoter escape complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10732496", "map_id": "none", "name": "RNA Polymerase I Transcription Initiation complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10739704", "map_id": "none", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_159450", "map_id": "CHEBI:33019", "name": "PPi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10739701", "map_id": "none", "name": "PPA2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10735146", "map_id": "none", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10735136", "map_id": "none", "name": "ATPase:ADP:Pi", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10735144", "map_id": "none", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10735138", "map_id": "none", "name": "ATPase:ATP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10735141", "map_id": "none", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10756939", "map_id": "none", "name": "RHOV binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756937", "map_id": "none", "name": "RHOV:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10756922", "map_id": "none", "name": "RHOV:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10756935", "map_id": "none", "name": "RHOV binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756931", "map_id": "none", "name": "RHOV effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q02088", "map_id": "Q02088", "name": "cdc8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27F1.02c", "map_id": "SPAC27F1.02c", "name": "cdc8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756933", "map_id": "none", "name": "RHOV:GTP:RHOV effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10752666", "map_id": "none", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6807054", "map_id": "CHEBI:17168", "name": "LTHSOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_6807057", "map_id": "CHEBI:17759", "name": "7-dehydroCHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10743177", "map_id": "none", "name": "Phosphorylation of cohesin by PLK1 at chromosomal arms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1598585", "compartment_display": "chromosome" }, { "id": "species_10743162", "map_id": "none", "name": "Sister Chromosomal Arms:Ac-Cohesin:PDS5:p-CDCA5:WAPAL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1598585", "compartment_display": "chromosome", "complex": "true" }, { "id": "Q9HFF5", "map_id": "Q9HFF5", "name": "pds5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC110.02", "map_id": "SPAC110.02", "name": "pds5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94364", "map_id": "O94364", "name": "wpl1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC428.17c", "map_id": "SPBC428.17c", "name": "wpl1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743174", "map_id": "none", "name": "Sister Chromosomal Arms:p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1598585", "compartment_display": "chromosome", "complex": "true" }, { "id": "species_10738046", "map_id": "P50528", "name": "plo1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC23C11.16", "map_id": "SPAC23C11.16", "name": "phospho-plo1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755724", "map_id": "none", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10755715", "map_id": "none", "name": "ISCA1:ISCA2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P78859", "map_id": "P78859", "name": "isa1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC645.03c", "map_id": "SPCC645.03c", "name": "isa1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43045", "map_id": "O43045", "name": "isa2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B9.17", "map_id": "SPBC3B9.17", "name": "isa2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10755703", "map_id": "none", "name": "GLRX5:2Fe-2S", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9HDW8", "map_id": "Q9HDW8", "name": "grx5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB2B4.02", "map_id": "SPAPB2B4.02", "name": "grx5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10755701", "map_id": "Q9HDW8", "name": "grx5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10755717", "map_id": "none", "name": "ISCA1:ISCA2:4Fe-4S", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:49883", "map_id": "CHEBI:49883", "name": "CHEBI:49883", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10755722", "map_id": "Q9UTL6", "name": "jac1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPAC144.08", "map_id": "SPAC144.08", "name": "jac1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743108", "map_id": "none", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10743106", "map_id": "none", "name": "FDXR:FAD", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O59710", "map_id": "O59710", "name": "arh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B8.01c", "map_id": "SPBC3B8.01c", "name": "arh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743104", "map_id": "none", "name": "FDXR:FADH2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10741701", "map_id": "none", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10741699", "map_id": "none", "name": "FXN:ISD11:NFS1:ISCU", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9UTC6", "map_id": "Q9UTC6", "name": "isu1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC227.13c", "map_id": "SPAC227.13c", "name": "isu1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74831", "map_id": "O74831", "name": "FXN(1-41)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1183.03c", "map_id": "SPCC1183.03c", "name": "FXN(1-41)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60068", "map_id": "O60068", "name": "isd11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC13G1.06c", "map_id": "SPBC13G1.06c", "name": "isd11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74351", "map_id": "O74351", "name": "PXLP-K258-NFS1-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC21D10.11c", "map_id": "SPBC21D10.11c", "name": "PXLP-K258-NFS1-2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741697", "map_id": "none", "name": "2 Iron:FXN:NFS1:ISD11:ISCU", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10754910", "map_id": "none", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10754907", "map_id": "none", "name": "OSBPL5,8,10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94512", "map_id": "O94512", "name": "obp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.08c", "map_id": "SPBC646.08c", "name": "obp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43021", "map_id": "O43021", "name": "OSBPL10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC354.07c", "map_id": "SPBC354.07c", "name": "OSBPL10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUA1", "map_id": "Q9UUA1", "name": "OSBPL8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC23B6.01c", "map_id": "SPCC23B6.01c", "name": "OSBPL8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742025", "map_id": "none", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498722", "map_id": "CHEBI:37646", "name": "2-acyl LPS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10741988", "map_id": "none", "name": "PLA2(11)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10741912", "map_id": "none", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10741765", "map_id": "O42916", "name": "ale1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10741897", "map_id": "none", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498724", "map_id": "CHEBI:52603", "name": "1-acyl LPS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10741983", "map_id": "none", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10729620", "map_id": "none", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729589", "map_id": "P06652", "name": "phospho-cdc25", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10729587", "map_id": "none", "name": "Proteolytic degradation of ubiquitinated-Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729585", "map_id": "none", "name": "Ub-p-S123-CDC25A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P06652", "map_id": "P06652", "name": "cdc25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729608", "map_id": "none", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10742125", "map_id": "none", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_110577", "map_id": "CHEBI:37563", "name": "CTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_1524101", "map_id": "CHEBI:16337", "name": "PA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524064", "map_id": "CHEBI:17962", "name": "CDP-DAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10742122", "map_id": "Q9P381", "name": "CDS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPBC13A2.03", "map_id": "SPBC13A2.03", "name": "CDS2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743262", "map_id": "none", "name": "Cohesin binds PDS5 and WAPAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743244", "map_id": "Q9HFF5", "name": "pds5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10743248", "map_id": "O94364", "name": "wpl1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10743250", "map_id": "none", "name": "Cohesin:PDS5:WAPAL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734651", "map_id": "none", "name": "Regulation of KIF20A (MKL2) by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734646", "map_id": "Q1MTQ7", "name": "klp9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC15D4.01c", "map_id": "SPBC15D4.01c", "name": "phospho-klp9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734649", "map_id": "Q1MTQ7", "name": "phospho-klp9", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10734620", "map_id": "P50528", "name": "phospho-plo1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10743288", "map_id": "none", "name": "Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1598585", "compartment_display": "chromosome" }, { "id": "species_2537690", "map_id": "none", "name": "Chromatin", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_1598585", "compartment_display": "chromosome", "complex": "false" }, { "id": "species_10743280", "map_id": "none", "name": "NIPBL:MAU2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O94459", "map_id": "O94459", "name": "ssl3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1687.18c", "map_id": "SPAC1687.18c", "name": "ssl3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09725", "map_id": "Q09725", "name": "mis4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC31A2.05c", "map_id": "SPAC31A2.05c", "name": "mis4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743286", "map_id": "none", "name": "Cohesin:PDS5:WAPAL:NIPBL:MAU2:Chromatin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734623", "map_id": "none", "name": "Regulation of KIF23 (MKLP1) by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734610", "map_id": "Q1MTQ7", "name": "klp9", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10734614", "map_id": "Q1MTQ7", "name": "phospho-klp9", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10752664", "map_id": "none", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6807477", "map_id": "CHEBI:64084", "name": "S-NADPHX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10752661", "map_id": "O94347", "name": "CARKD", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPCC61.03", "map_id": "SPCC61.03", "name": "CARKD", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10752656", "map_id": "none", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6807473", "map_id": "CHEBI:64085", "name": "R-NADPHX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10752653", "map_id": "none", "name": "APOA1BP dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O13725", "map_id": "O13725", "name": "mug182", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC15A10.05c", "map_id": "SPAC15A10.05c", "name": "mug182", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753139", "map_id": "none", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389620", "map_id": "CHEBI:456215", "name": "AMP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_192305", "map_id": "CHEBI:57945", "name": "NADH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6809289", "map_id": "CHEBI:74452", "name": "NMNH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_193465", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10753136", "map_id": "Q9Y7J0", "name": "NUDT12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "SPBC1778.03c", "map_id": "SPBC1778.03c", "name": "NUDT12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757787", "map_id": "none", "name": "DKC1 binds SHQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10757783", "map_id": "O43076", "name": "shq1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC8D2.13", "map_id": "SPBC8D2.13", "name": "shq1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734902", "map_id": "O14007", "name": "cbf5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC29A4.04c", "map_id": "SPAC29A4.04c", "name": "cbf5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757785", "map_id": "none", "name": "DKC1:SHQ1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O43076", "map_id": "O43076", "name": "shq1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14007", "map_id": "O14007", "name": "cbf5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753499", "map_id": "none", "name": "TRiC/CCT binds unfolded G-protein beta subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738448", "map_id": "none", "name": "CCT/TRiC:ADP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P87153", "map_id": "P87153", "name": "cct7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC25H2.12c", "map_id": "SPBC25H2.12c", "name": "cct7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94501", "map_id": "O94501", "name": "cct1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC12D12.03", "map_id": "SPBC12D12.03", "name": "cct1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UTM4", "map_id": "Q9UTM4", "name": "cct5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1420.02c", "map_id": "SPAC1420.02c", "name": "cct5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94515", "map_id": "O94515", "name": "cct6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.11", "map_id": "SPBC646.11", "name": "cct6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74341", "map_id": "O74341", "name": "cct3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1A4.08c", "map_id": "SPBC1A4.08c", "name": "cct3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50999", "map_id": "P50999", "name": "cct4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC106.06", "map_id": "SPBC106.06", "name": "cct4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10753491", "map_id": "Q10282", "name": "git5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC32H8.07", "map_id": "SPBC32H8.07", "name": "git5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10753497", "map_id": "none", "name": "Unfolded G-protein beta subunit:CCT/TRiC:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10282", "map_id": "Q10282", "name": "git5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753507", "map_id": "none", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10753503", "map_id": "none", "name": "Unfolded G-protein beta subunit:CCT/TRiC:ATP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10738452", "map_id": "none", "name": "Association of CCT/TriC with sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738450", "map_id": "none", "name": "CCT/TRiC:ADP:Sphingosine kinase 1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14159", "map_id": "O14159", "name": "lcb4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753505", "map_id": "none", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10752940", "map_id": "none", "name": "ARFGAPs stimulate ARF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10752857", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "O13690", "map_id": "O13690", "name": "GBF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC211.03c", "map_id": "SPBC211.03c", "name": "GBF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13946", "map_id": "O13946", "name": "erv25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23H4.03c", "map_id": "SPAC23H4.03c", "name": "erv25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87140", "map_id": "P87140", "name": "sec21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC57A7.10c", "map_id": "SPAC57A7.10c", "name": "sec21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74767", "map_id": "O74767", "name": "sec28", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC24C6.05", "map_id": "SPBC24C6.05", "name": "sec28", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10491", "map_id": "Q10491", "name": "sec74", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26F1.01", "map_id": "SPAC26F1.01", "name": "sec74", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42937", "map_id": "O42937", "name": "sec27", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16C6.13c", "map_id": "SPBC16C6.13c", "name": "sec27", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7R8", "map_id": "Q9P7R8", "name": "GBF1", "type": 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"protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC13G1.11", "map_id": "SPBC13G1.11", "name": "ykt6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74891", "map_id": "O74891", "name": "ret3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC576.07", "map_id": "SPCC576.07", "name": "ret3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7I9", "map_id": "Q9P7I9", "name": "emp24", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC24B10.17", "map_id": "SPCC24B10.17", "name": "emp24", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13932", "map_id": "O13932", "name": "bet1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23C4.13", "map_id": "SPAC23C4.13", "name": "bet1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P11620", "map_id": "P11620", "name": "ypt1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1703.10", "map_id": "SPBC1703.10", "name": "ypt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10367", "map_id": "Q10367", "name": "glo3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22E12.17c", "map_id": "SPAC22E12.17c", "name": "glo3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13770", "map_id": "O13770", "name": "TMED7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17A5.08", "map_id": "SPAC17A5.08", "name": "TMED7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14324", "map_id": "O14324", "name": "TMED9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16E9.09c", "map_id": "SPBC16E9.09c", "name": "TMED9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94270", "map_id": "O94270", "name": "erd2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP8B7.22", "map_id": "SPBP8B7.22", "name": "erd2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09857", "map_id": "Q09857", "name": "uso1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC29E6.03c", "map_id": "SPAC29E6.03c", "name": "uso1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10752937", "map_id": "none", "name": "RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_432051", "compartment_display": "transport vesicle", "complex": "true" }, { "id": "species_10752792", "map_id": "Q10367", "name": "glo3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10746137", "map_id": "none", "name": "ARF4:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10752725", "map_id": "none", "name": "Homologues of GBF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10753303", "map_id": "none", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10753301", "map_id": "none", "name": "SEC22B:STX18:USE1L:BNIP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9Y7L0", "map_id": "Q9Y7L0", "name": "sec22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2A9.08c", "map_id": "SPBC2A9.08c", "name": "sec22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94531", "map_id": "O94531", "name": "ufe1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC895.04c", "map_id": "SPCC895.04c", "name": "ufe1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13785", "map_id": "O13785", "name": "use1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17G6.07c", "map_id": "SPAC17G6.07c", "name": "use1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42852", "map_id": "O42852", "name": "sec20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23A1.15c", "map_id": "SPAC23A1.15c", "name": "sec20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10739129", "map_id": "Q9P4X4", "name": "sec17", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC959.02", "map_id": "SPAC959.02", "name": "sec17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749814", "map_id": "none", "name": "NSF hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P7Q4", "map_id": "Q9P7Q4", "name": "sec18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1834.11c", "map_id": "SPAC1834.11c", "name": "sec18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10753292", "map_id": "none", "name": "SEC22B:STX18:USE1:BNIP1L:3xSNAPs:NSF hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9P4X4", "map_id": "Q9P4X4", "name": "sec17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749851", "map_id": "none", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10749847", "map_id": "none", "name": "cis-SNARE", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "O13644", "map_id": "O13644", "name": "sed5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC8D2.14c", "map_id": "SPBC8D2.14c", "name": "sed5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74534", "map_id": "O74534", "name": "sly1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC74.01", "map_id": "SPCC74.01", "name": "sly1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94651", "map_id": "O94651", "name": "pep12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC31E1.04", "map_id": "SPBC31E1.04", "name": "pep12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7G5", "map_id": "Q9P7G5", "name": "bos1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAP14E8.03", "map_id": "SPAP14E8.03", "name": "bos1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749849", "map_id": "none", "name": "cis-SNARE:NSF hexamer:3xSNAP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10754292", "map_id": "none", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10754282", "map_id": "none", "name": "RAB7A:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10754284", "map_id": "none", "name": "RAB7A:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10754290", "map_id": "Q09830", "name": "TBC1D2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC4G8.04", "map_id": "SPAC4G8.04", "name": "TBC1D2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740660", "map_id": "none", "name": "MVB Vesicle Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740430", "map_id": "none", "name": "ESCRT-III", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10740658", "map_id": "none", "name": "ESCRT-II/Cargo Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "O74967", "map_id": "O74967", "name": "vps25", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4B4.06", "map_id": "SPBC4B4.06", "name": "vps25", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43038", "map_id": "O43038", "name": "vps36", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B9.09", "map_id": "SPBC3B9.09", "name": "vps36", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94663", "map_id": "O94663", "name": "dot2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC651.05c", "map_id": "SPBC651.05c", "name": "dot2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740526", "map_id": "none", "name": "ESCRT-III/Cargo Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "species_10740656", "map_id": "none", "name": "ESCRT-II", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10753584", "map_id": "none", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10753579", "map_id": "none", "name": "RAB1:GTP:TBC1D20", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "O94661", "map_id": "O94661", "name": "gyp10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC651.03c", "map_id": "SPBC651.03c", "name": "gyp10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749719", "map_id": "none", "name": "RAB1:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10753577", "map_id": "O94661", "name": "gyp10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "reaction_10754588", "map_id": "none", "name": "FCHo proteins bind nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10754497", "map_id": "none", "name": "PI(4,5)P2:AP-2:clathrin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10754509", "map_id": "none", "name": "Homologues of SGIP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UUJ3", "map_id": "Q9UUJ3", "name": "rga9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1952.16", "map_id": "SPAC1952.16", "name": "rga9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10199", "map_id": "Q10199", "name": "imp2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC11C11.02", "map_id": "SPBC11C11.02", "name": "imp2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43059", "map_id": "O43059", "name": "syp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4C3.06", "map_id": "SPBC4C3.06", "name": "syp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09822", "map_id": "Q09822", "name": "cdc15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC20G8.05c", "map_id": "SPAC20G8.05c", "name": "cdc15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09697", "map_id": "Q09697", "name": "rga8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13A11.01c", "map_id": "SPAC13A11.01c", "name": "rga8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754481", "map_id": "none", "name": "Homologues of EPS15", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9USZ7", "map_id": "Q9USZ7", "name": "end3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC11G11.02c", "map_id": "SPBC11G11.02c", "name": "end3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10172", "map_id": "Q10172", "name": "pan1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC25G10.09c", "map_id": "SPAC25G10.09c", "name": "pan1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94685", "map_id": "O94685", "name": "ucp8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC83.01", "map_id": "SPBC83.01", "name": "ucp8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754426", "map_id": "none", "name": "ITSNs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10754471", "map_id": "none", "name": "FCHO1,2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10754491", "map_id": "none", "name": "Homologues of REPS1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10754511", "map_id": "none", "name": "PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10755426", "map_id": "none", "name": "Initial binding of AP-2 and clathrin to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10754388", "map_id": "none", "name": "AP-2 Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10738801", "map_id": "none", "name": "Clathrin Triskelion", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10753408", "map_id": "none", "name": "RIC1:RGP1 recruits RAB6:GDP to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10753400", "map_id": "none", "name": "RIC1:RGP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "O60183", "map_id": "O60183", "name": "sat1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC23E6.08", "map_id": "SPBC23E6.08", "name": "sat1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42656", "map_id": "O42656", "name": "ric1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1851.04c", "map_id": "SPAC1851.04c", "name": "ric1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10753388", "map_id": "none", "name": "RAB6:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10753406", "map_id": "none", "name": "RAB6:GDP:RIC1:RGP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10753602", "map_id": "none", "name": "RAB43 hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10753595", "map_id": "none", "name": "RAB43:GTP:USP6NL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "Q10496", "map_id": "Q10496", "name": "gyp51", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26F1.09", "map_id": "SPAC26F1.09", "name": "gyp51", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10753599", "map_id": "none", "name": "RAB43:GDP:USP6NL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10755664", "map_id": "none", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane" }, { "id": "species_10755636", "map_id": "none", "name": "GGC-RAB1:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O60112", "map_id": "O60112", "name": "CHML", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC15C4.03", "map_id": "SPBC15C4.03", "name": "CHML", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10755437", "map_id": "none", "name": "GDIs,CHMs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755646", "map_id": "none", "name": "GGC-RAB1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13946", "compartment_display": "transport vesicle membrane", "complex": "true" }, { "id": "species_10755661", "map_id": "none", "name": "TRAPPCs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74748", "map_id": "O74748", "name": "trs85-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1734.07c", "map_id": "SPBC1734.07c", "name": "trs85-2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14251", "map_id": "O14251", "name": "trs120", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6G10.05c", "map_id": "SPAC6G10.05c", "name": "trs120", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USZ5", "map_id": "Q9USZ5", "name": "trs20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC11G11.04", "map_id": "SPBC11G11.04", "name": "trs20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P6P5", "map_id": "Q9P6P5", "name": "bet3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC644.18c", "map_id": "SPAC644.18c", "name": "bet3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09784", "map_id": "Q09784", "name": "TRAPPC6A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13G6.05c", "map_id": "SPAC13G6.05c", "name": "TRAPPC6A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7N9", "map_id": "Q9P7N9", "name": "trs31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1718.05", "map_id": "SPBC1718.05", "name": "trs31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13732", "map_id": "O13732", "name": "TRAPPC2L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC15A10.12c", "map_id": "SPAC15A10.12c", "name": "TRAPPC2L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74501", "map_id": "O74501", "name": "TRAPPC10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC285.14", "map_id": "SPCC285.14", "name": "TRAPPC10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43041", "map_id": "O43041", "name": "trs23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B9.12", "map_id": "SPBC3B9.12", "name": "trs23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753415", "map_id": "none", "name": "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10753412", "map_id": "none", "name": "RAB6:GTP:RIC1:RGP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10755452", "map_id": "none", "name": "RAB3 GEFs exchange GTP for GDP on RAB3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane" }, { "id": "species_10755439", "map_id": "none", "name": "GGC-RAB3A:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755447", "map_id": "none", "name": "GGC-RAB3A:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "true" }, { "id": "species_10755449", "map_id": "O13930", "name": "sec2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC23C4.10", "map_id": "SPAC23C4.10", "name": "sec2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755040", "map_id": "none", "name": "Endophilins recruit synaptojanins to the clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10755020", "map_id": "none", "name": "PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9P6L5", "map_id": "Q9P6L5", "name": "end4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC688.11", "map_id": "SPAC688.11", "name": "end4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UU85", "map_id": "Q9UU85", "name": "ppk38", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCP1E11.02", "map_id": "SPCP1E11.02", "name": "ppk38", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43066", "map_id": "O43066", "name": "ppk30", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC6B1.02", "map_id": "SPBC6B1.02", "name": "ppk30", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60167", "map_id": "O60167", "name": "SNAP91", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19F8.03c", "map_id": "SPBC19F8.03c", "name": "SNAP91", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USS2", "map_id": "Q9USS2", "name": "ppk29", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC557.04", "map_id": "SPBC557.04", "name": "ppk29", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10755033", "map_id": "none", "name": "PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10753710", "map_id": "none", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753701", "map_id": "none", "name": "ARF1:GTP:CYTH1,2,3,4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10753707", "map_id": "none", "name": "ARF1:GDP:CYTH1,2,3,4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10753246", "map_id": "none", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753235", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10753239", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10754846", "map_id": "none", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10738025", "map_id": "Q92356", "name": "syb1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10754842", "map_id": "none", "name": "PICALMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10754844", "map_id": "none", "name": "PICALM:VAMP2,3,8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10753617", "map_id": "none", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753612", "map_id": "none", "name": "STX5:PalmC-YKT6:BET1L:GOSR1:NSF hexamer:3xSNAPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "Q09730", "map_id": "Q09730", "name": "sft1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC31A2.13c", "map_id": "SPAC31A2.13c", "name": "sft1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09835", "map_id": "Q09835", "name": "gos1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4G8.10", "map_id": "SPAC4G8.10", "name": "gos1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10753102", "map_id": "O13644", "name": "sed5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10753091", "map_id": "Q09835", "name": "gos1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10753100", "map_id": "none", "name": "Homologues of BET1L", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10753002", "map_id": "O60073", "name": "ykt6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10737431", "map_id": "none", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737423", "map_id": "none", "name": "SAR1B:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737428", "map_id": "Q10659", "name": "spo14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC3H7.01", "map_id": "SPBC3H7.01", "name": "spo14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749854", "map_id": "none", "name": "NSF ATPase activity dissociates cis-SNARE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10749821", "map_id": "O13932", "name": "bet1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "species_10749837", "map_id": "none", "name": "STX5,17", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10749828", "map_id": "O74534", "name": "sly1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10749845", "map_id": "none", "name": "ER-to-ERGIC v-SNARES", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10749823", "map_id": "Q9P7G5", "name": "bos1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "reaction_10753581", "map_id": "none", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10749883", "map_id": "none", "name": "RAB1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10754326", "map_id": "none", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10754316", "map_id": "none", "name": "RAB7:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10754318", "map_id": "none", "name": "RAB7:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "species_10754324", "map_id": "Q9UUH7", "name": "gyp7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC630.05", "map_id": "SPAC630.05", "name": "gyp7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753567", "map_id": "none", "name": "cis-SNARE binds SNAPs and NSF hexamer at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10753563", "map_id": "none", "name": "STX6:STX16:VTI1A:VAMP4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "P78768", "map_id": "P78768", "name": "vti1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B9.10", "map_id": "SPBC3B9.10", "name": "vti1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9HGN3", "map_id": "Q9HGN3", "name": "tlg1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC36B7.07", "map_id": "SPBC36B7.07", "name": "tlg1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P6P1", "map_id": "Q9P6P1", "name": "tlg2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC823.05c", "map_id": "SPAC823.05c", "name": "tlg2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10753565", "map_id": "none", "name": "STX6:STX16:VTI1A:VAMP4:NSF hexamer:3xSNAPs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10752744", "map_id": "none", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10752737", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10752741", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10754916", "map_id": "none", "name": "Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10754884", "map_id": "none", "name": "PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10757826", "map_id": "none", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9648300", "map_id": "LigandDisplayForward?ligandId=83", "name": "chlorpromazine", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10754724", "map_id": "none", "name": "AP2:chlorpromazine", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10754525", "map_id": "none", "name": "AAK1 phosphorylates AP-2 mu subunit at T156", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10754515", "map_id": "none", "name": "PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10754522", "map_id": "none", "name": "PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10755038", "map_id": "none", "name": "SYNJ hydrolyze PI(4,5)P2 to PI(4)P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10755035", "map_id": "none", "name": "PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10749891", "map_id": "none", "name": "CSNK1D phosphorylates SEC23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10749871", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "O13637", "map_id": "O13637", "name": "sec31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC8D2.20c", "map_id": "SPBC8D2.20c", "name": "sec31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87109", "map_id": "P87109", "name": "SEC23IP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC20G8.02", "map_id": "SPAC20G8.02", "name": "SEC23IP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10149", "map_id": "Q10149", "name": "GORASP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1D4.02c", "map_id": "SPAC1D4.02c", "name": "GORASP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749807", "map_id": "none", "name": "p-SEC24", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737297", "map_id": "none", "name": "SEC31A:SEC13:SEC23IP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10749877", "map_id": "none", "name": "COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "species_10749768", "map_id": "none", "name": "TRAPPCII", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10749875", "map_id": "O74873", "name": "phospho-sec231", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10749888", "map_id": "P40235", "name": "hhp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "false" }, { "id": "SPBC3H7.15", "map_id": "SPBC3H7.15", "name": "hhp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737888", "map_id": "none", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737859", "map_id": "none", "name": "Arf1-GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737863", "map_id": "none", "name": "Arf1-GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10737885", "map_id": "none", "name": "Homologues of GBF1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10753554", "map_id": "none", "name": "SNAPs and NSF hexamer bind cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10753550", "map_id": "none", "name": "STX10:STX16:VTI1A:VAMP3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "species_10753552", "map_id": "none", "name": "STX10:STX16:VTI1A:VAMP3:NSF hexamer:SNAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "reaction_10753606", "map_id": "none", "name": "RAB43:GTP binds USP8NL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10753593", "map_id": "none", "name": "RAB43:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "species_10753604", "map_id": "Q10496", "name": "gyp51", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10755079", "map_id": "none", "name": "HSPA8-mediated ATP hydrolysis promotes vesicle uncoating", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane" }, { "id": "species_10755070", "map_id": "none", "name": "PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane", "complex": "true" }, { "id": "O13773", "map_id": "O13773", "name": "ucp7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17A5.12", "map_id": "SPAC17A5.12", "name": "ucp7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10755072", "map_id": "none", "name": "PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane", "complex": "true" }, { "id": "species_10755076", "map_id": "none", "name": "clathrin:HSPA8:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10749918", "map_id": "none", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737373", "map_id": "none", "name": "COPII cargo receptors:SAR1B:GTP:SEC23:SEC24", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10737371", "map_id": "none", "name": "SEC23A:SEC24C,D:GOSR2,STX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10753635", "map_id": "none", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753631", "map_id": "none", "name": "TRIP11:cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_432051", "compartment_display": "transport vesicle", "complex": "true" }, { "id": "O42903", "map_id": "O42903", "name": "TRIP11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC119.12", "map_id": "SPBC119.12", "name": "TRIP11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60109", "map_id": "O60109", "name": "ALPI", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC14F5.13c", "map_id": "SPBC14F5.13c", "name": "ALPI", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10753633", "map_id": "none", "name": "ARF1:GTP:TRIP11:cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10752733", "map_id": "none", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10752729", "map_id": "none", "name": "USO1 homodimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10752731", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10753120", "map_id": "none", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753116", "map_id": "none", "name": "cis-Golgi cis SNARE bundle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10753118", "map_id": "none", "name": "cis-SNARE:3xSNAP:NSF hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10753237", "map_id": "none", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753233", "map_id": "none", "name": "RAB1:GTP:GBF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10753123", "map_id": "none", "name": "NSF ATPase activity dissociates cis-SNARE at cis-Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753106", "map_id": "Q9P7G5", "name": "bos1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10753074", "map_id": "O13932", "name": "bet1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10753260", "map_id": "none", "name": "ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753256", "map_id": "none", "name": "Golgi-to-ER cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10753241", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GTP:coatomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10753250", "map_id": "Q9Y7L0", "name": "sec22", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10753070", "map_id": "none", "name": "p24 dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10753258", "map_id": "none", "name": "RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10737445", "map_id": "none", "name": "SEC31:SEC13 and v-SNARE recruitment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10737379", "map_id": "none", "name": "COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O14029", "map_id": "O14029", "name": "sec16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC29B12.07", "map_id": "SPAC29B12.07", "name": "sec16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10737310", "map_id": "none", "name": "ER-to-ERGIC v-SNARES", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10737381", "map_id": "none", "name": "COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10754333", "map_id": "none", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane" }, { "id": "species_10747277", "map_id": "O94272", "name": "atg8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane", "complex": "false" }, { "id": "SPBP8B7.24c", "map_id": "SPBP8B7.24c", "name": "atg8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754329", "map_id": "Q9UUH7", "name": "gyp7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5683636", "compartment_display": "autophagosome", "complex": "false" }, { "id": "species_10754331", "map_id": "none", "name": "TBC1D25:ATG8 homoogues", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane", "complex": "true" }, { "id": "O94272", "map_id": "O94272", "name": "atg8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUH7", "map_id": "Q9UUH7", "name": "gyp7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10754886", "map_id": "none", "name": "CLASP proteins and cargo are recruited to the nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10754878", "map_id": "none", "name": "CLASP proteins:cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10754880", "map_id": "none", "name": "PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10755085", "map_id": "none", "name": "Clathrin recruits auxilins to the clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane" }, { "id": "species_10755081", "map_id": "none", "name": "PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane", "complex": "true" }, { "id": "species_10739268", "map_id": "O13773", "name": "ucp7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10755083", "map_id": "none", "name": "PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10749791", "map_id": "none", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10737367", "map_id": "none", "name": "SEC24C,D", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737361", "map_id": "none", "name": "GOSR2,STX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10737369", "map_id": "O74873", "name": "sec231", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10754599", "map_id": "none", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10754595", "map_id": "Q09718", "name": "apm4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10749451", "map_id": "O14399", "name": "ubl1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC12D12.08c", "map_id": "SPBC12D12.08c", "name": "ubl1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754591", "map_id": "Q09718", "name": "apm4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10753248", "map_id": "none", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753032", "map_id": "none", "name": "RAB1:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10738021", "map_id": "none", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738012", "map_id": "Q9USH7", "name": "psy1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "SPCC825.03c", "map_id": "SPCC825.03c", "name": "psy1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10738014", "map_id": "Q92356", "name": "syb1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "false" }, { "id": "species_10738010", "map_id": "O74786", "name": "sec9", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10738016", "map_id": "Q92356", "name": "syb1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10738018", "map_id": "none", "name": "Vamp8:SNAP23:Syn4 Secretory granule docking and fusion complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9USH7", "map_id": "Q9USH7", "name": "psy1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753384", "map_id": "none", "name": "COPI vesicle uncoating at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10753382", "map_id": "none", "name": "RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9C0W8", "map_id": "Q9C0W8", "name": "tip20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC691.02c", "map_id": "SPBC691.02c", "name": "tip20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10753380", "map_id": "none", "name": "Golgi-to-ER cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10752783", "map_id": "none", "name": "coatomer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10753346", "map_id": "none", "name": "p24 dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10755090", "map_id": "none", "name": "Dynamin-mediated GTP hydrolysis promotes vesicle scission", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10753713", "map_id": "none", "name": "PLA2s hydrolyze phospholipids at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_6814303", "map_id": "CHEBI:35366", "name": "fatty acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8848483", "map_id": "CHEBI:17504", "name": "2-lysophosphatidylcholine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "reaction_10740639", "map_id": "none", "name": "ESCRT Disassembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10740409", "map_id": "O14296", "name": "vps24", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740404", "map_id": "O14177", "name": "did4", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740428", "map_id": "O74422", "name": "CHMP7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740414", "map_id": "Q9P7F7", "name": "snf7", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740423", "map_id": "O94318", "name": "vps20", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740620", "map_id": "none", "name": "Ubiquinated and PIP3 Endosmal Membrane Bound Cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "species_10740636", "map_id": "none", "name": "Vps/Vta1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13703", "map_id": "O13703", "name": "vts1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13F5.04c", "map_id": "SPAC13F5.04c", "name": "vts1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753614", "map_id": "none", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753610", "map_id": "none", "name": "STX:PalmC-YKT6:BET1L:GOSR1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10749856", "map_id": "none", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10737419", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13945", "compartment_display": "ER to Golgi transport vesicle membrane", "complex": "true" }, { "id": "species_10749770", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle", "complex": "true" }, { "id": "reaction_10753557", "map_id": "none", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10753539", "map_id": "Q9HGN3", "name": "tlg1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "species_10753544", "map_id": "Q9P6P1", "name": "tlg2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "species_10753548", "map_id": "Q92356", "name": "syb1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "species_10753546", "map_id": "P78768", "name": "vti1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "false" }, { "id": "reaction_10753703", "map_id": "none", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753667", "map_id": "none", "name": "CYTH1,2,3,4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10749795", "map_id": "none", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10737433", "map_id": "Q9UUI5", "name": "sec24", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737302", "map_id": "Q9Y7L0", "name": "sec22", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10749793", "map_id": "none", "name": "SEC24A,B:SEC23A:SEC22B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10752739", "map_id": "none", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "reaction_10754348", "map_id": "none", "name": "TBC1D14 binds RAB11 and ULK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane" }, { "id": "species_10754344", "map_id": "Q09844", "name": "TBC1D14", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_261116", "compartment_display": "recycling endosome", "complex": "false" }, { "id": "SPAC23D3.03c", "map_id": "SPAC23D3.03c", "name": "TBC1D14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754335", "map_id": "P17610", "name": "ypt3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane", "complex": "false" }, { "id": "SPAC18G6.03", "map_id": "SPAC18G6.03", "name": "ypt3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754339", "map_id": "Q9Y7T4", "name": "atg1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_261116", "compartment_display": "recycling endosome", "complex": "false" }, { "id": "SPCC63.08c", "map_id": "SPCC63.08c", "name": "atg1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754346", "map_id": "none", "name": "TBC1D14:RAB11:ULK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane", "complex": "true" }, { "id": "P17610", "map_id": "P17610", "name": "ypt3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7T4", "map_id": "Q9Y7T4", "name": "atg1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09844", "map_id": "Q09844", "name": "TBC1D14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749777", "map_id": "none", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle" }, { "id": "species_10749774", "map_id": "none", "name": "COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13959", "compartment_display": "COPII-coated ER to Golgi transport vesicle", "complex": "true" }, { "id": "reaction_10754306", "map_id": "none", "name": "TBC1D10A (EPI64) binds ARF6:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane" }, { "id": "species_10754295", "map_id": "Q9Y7J5", "name": "TBC1D10A", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_19363", "compartment_display": "microvillus", "complex": "false" }, { "id": "species_10754302", "map_id": "none", "name": "ARF6:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane", "complex": "true" }, { "id": "Q9Y7Z2", "map_id": "Q9Y7Z2", "name": "arf6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1539.08", "map_id": "SPBC1539.08", "name": "arf6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754304", "map_id": "none", "name": "TBC1D10A:ARF6:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane", "complex": "true" }, { "id": "reaction_10755558", "map_id": "none", "name": "RIC1-RGP1 exchanges GTP for GDP on RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10755545", "map_id": "none", "name": "GGC-RAB6:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755549", "map_id": "none", "name": "GGC-RAB6:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "species_10755555", "map_id": "none", "name": "RIC1:RGP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10745653", "map_id": "none", "name": "CLAT:AP1:CLVS bind PI(3,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10745649", "map_id": "none", "name": "CLAT:AP1:CLVS", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "Q9UU81", "map_id": "Q9UU81", "name": "apl4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCP1E11.06", "map_id": "SPCP1E11.06", "name": "apl4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7N2", "map_id": "Q9P7N2", "name": "vas2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAP27G11.06c", "map_id": "SPAP27G11.06c", "name": "vas2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5334668", "map_id": "CHEBI:16851", "name": "PI(3,5)P2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "false" }, { "id": "species_10745651", "map_id": "none", "name": "CLAT:AP1:CLVS:PI(3,5)P2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20592", "compartment_display": "clathrin-coated endocytic vesicle", "complex": "true" }, { "id": "reaction_10753295", "map_id": "none", "name": "NSF ATPase activity dissociates cis-SNARE at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10753288", "map_id": "O13785", "name": "use1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10753278", "map_id": "O42852", "name": "sec20", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10753283", "map_id": "O94531", "name": "ufe1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10755022", "map_id": "none", "name": "BAR domain proteins recruit dynamin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10755018", "map_id": "none", "name": "DNM:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755016", "map_id": "none", "name": "PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10738030", "map_id": "none", "name": "Vamp2 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10738023", "map_id": "Q92356", "name": "syb1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_216813", "compartment_display": "secretory granule membrane", "complex": "false" }, { "id": "species_10738027", "map_id": "none", "name": "Vamp2:SNAP23:Syn4 Secretory granule docking and fusion complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10754913", "map_id": "none", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10742317", "map_id": "O13853", "name": "its3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10753273", "map_id": "none", "name": "ARFGAPs stimulate ARF GTPase activity at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10753270", "map_id": "none", "name": "RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_432051", "compartment_display": "transport vesicle", "complex": "true" }, { "id": "reaction_10755570", "map_id": "none", "name": "p-ULK1 phosphorylates DENND3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10755563", "map_id": "Q9Y7Q7", "name": "DENND3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC297.05", "map_id": "SPCC297.05", "name": "phospho-p-S472,S490-DENND3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10755567", "map_id": "Q9Y7Q7", "name": "phospho-p-S472,S490-DENND3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10746793", "map_id": "Q9Y7T4", "name": "phospho-atg1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10753243", "map_id": "none", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "reaction_10755087", "map_id": "none", "name": "Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_24339", "compartment_display": "clathrin-coated endocytic vesicle membrane" }, { "id": "species_10755046", "map_id": "none", "name": "HSPA8:ATP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10754726", "map_id": "none", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10754720", "map_id": "none", "name": "AP-2 YXXPhi cargo", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10754722", "map_id": "none", "name": "AP-2:cargo", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10749915", "map_id": "none", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10755587", "map_id": "none", "name": "DENND3 exchanges GTP for GDP on RAB12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane" }, { "id": "species_10755574", "map_id": "none", "name": "GCC-RAB12:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755582", "map_id": "none", "name": "GGC-RAB12:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_262783", "compartment_display": "recycling endosome membrane", "complex": "true" }, { "id": "species_10755584", "map_id": "none", "name": "DENND3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9Y7Q7", "map_id": "Q9Y7Q7", "name": "phospho-p-S472,S490-DENND3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755519", "map_id": "none", "name": "RAB8 GEFs exchange GTP for GDP on RAB8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane" }, { "id": "species_10755502", "map_id": "none", "name": "GGC-RAB8:GDP:GDIs,CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755514", "map_id": "none", "name": "GGC-RAB8:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_263163", "compartment_display": "trans-Golgi network membrane", "complex": "true" }, { "id": "species_10755516", "map_id": "none", "name": "RAB8 GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13930", "map_id": "O13930", "name": "sec2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "C6Y4C9", "map_id": "C6Y4C9", "name": "spo13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1183.12", "map_id": "SPCC1183.12", "name": "spo13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10752787", "map_id": "none", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane" }, { "id": "species_10752785", "map_id": "none", "name": "RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_6791047", "compartment_display": "endoplasmic reticulum-Golgi intermediate compartment membrane", "complex": "true" }, { "id": "reaction_10754708", "map_id": "none", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10754684", "map_id": "none", "name": "UBQLN2,1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10169", "map_id": "Q10169", "name": "dph1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B8.05", "map_id": "SPBC3B8.05", "name": "dph1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42967", "map_id": "O42967", "name": "UBQLN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1E8.02", "map_id": "SPBC1E8.02", "name": "UBQLN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754704", "map_id": "none", "name": "EPS15,EPN1,EPN2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74423", "map_id": "O74423", "name": "ent1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC162.07", "map_id": "SPCC162.07", "name": "ent1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78813", "map_id": "P78813", "name": "EPN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC794.11c", "map_id": "SPCC794.11c", "name": "EPN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754706", "map_id": "none", "name": "UNQLNs:UIM proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10735482", "map_id": "none", "name": "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10735478", "map_id": "none", "name": "CCNA:p-Y15-CDK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10735480", "map_id": "none", "name": "CCNA:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10729374", "map_id": "none", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_29604", "map_id": "CHEBI:61404", "name": "dATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728770", "map_id": "none", "name": "RNA primer:origin duplex:DNA polymerase alpha:primase complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733290", "map_id": "none", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733288", "map_id": "none", "name": "multi-ubiquitinated phospho-(T286) Cyclin D1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10735822", "map_id": "none", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10735523", "map_id": "O13286", "name": "srw1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10735525", "map_id": "O13286", "name": "phospho-srw1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10735825", "map_id": "none", "name": "CAK-mediated phosphorylation of Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10728773", "map_id": "none", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10733284", "map_id": "none", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10733270", "map_id": "none", "name": "phospho(T286)-Cyclin D1:Cdk4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733282", "map_id": "none", "name": "phospho(T286)-Cyclin D1:Cdk4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10733286", "map_id": "none", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10733266", "map_id": "none", "name": "Homologues of p-T286-CCND1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733278", "map_id": "none", "name": "Homologues of p-T286-CCND1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10735527", "map_id": "none", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10735466", "map_id": "none", "name": "CCNA:CDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10735468", "map_id": "none", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735434", "map_id": "none", "name": "CCNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10740250", "map_id": "none", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76103", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_75967", "map_id": "CHEBI:37554", "name": "FACoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_549167", "map_id": "CHEBI:17855", "name": "TAG", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10740247", "map_id": "O74850", "name": "dga1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10733412", "map_id": "none", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76108", "map_id": "CHEBI:29089", "name": "1,2-daG3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10733405", "map_id": "Q9UUJ6", "name": "ned1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC1952.13", "map_id": "SPAC1952.13", "name": "ned1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10752220", "map_id": "none", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6800352", "map_id": "CHEBI:17389", "name": "2AG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10752213", "map_id": "O74850", "name": "dga1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10735159", "map_id": "none", "name": "Phosphorylation of TSC2 by PKB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735156", "map_id": "Q9UUG9", "name": "phospho-tsc2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10735185", "map_id": "none", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane" }, { "id": "species_10735181", "map_id": "none", "name": "RHEB:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17938", "compartment_display": "lysosomal membrane", "complex": "true" }, { "id": "reaction_10738133", "map_id": "none", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736802", "map_id": "none", "name": "p-AMPK heterotrimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10738128", "map_id": "none", "name": "p-AMPK heterotrimer:AMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10735204", "map_id": "none", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731629", "map_id": "Q9C0Z7", "name": "rps602", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735201", "map_id": "Q9C0Z7", "name": "phospho-rps602", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735194", "map_id": "Q12706", "name": "phospho-psk1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10757820", "map_id": "none", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9678687", "map_id": "LigandDisplayForward?ligandId=6031", "name": "sirolimus", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10757818", "map_id": "none", "name": "FKBP1A:sirolimus", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10738131", "map_id": "none", "name": "p-AMPK phosphorylates TSC1:TSC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735168", "map_id": "none", "name": "TSC1:TSC2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09778", "map_id": "Q09778", "name": "tsc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22F3.13", "map_id": "SPAC22F3.13", "name": "tsc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUG9", "map_id": "Q9UUG9", "name": "phospho-tsc2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10738126", "map_id": "none", "name": "TSC1:p-S1387-TSC2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10735211", "map_id": "none", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735209", "map_id": "Q10475", "name": "phospho-tif471", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10735174", "map_id": "none", "name": "Phosphorylation of complexed TSC2 by PKB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735172", "map_id": "none", "name": "TSC1:Inhibited TSC2-1-P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746540", "map_id": "none", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746523", "map_id": "none", "name": "RRAGA, RRAGB:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746536", "map_id": "none", "name": "RRAGC,RRAGD:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746538", "map_id": "none", "name": "RagA,B:GTP:RagC,D:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10741434", "map_id": "none", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741400", "map_id": "P24339", "name": "cut7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC25G10.07c", "map_id": "SPAC25G10.07c", "name": "cut7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741402", "map_id": "none", "name": "Kinesin-5 homotetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P24339", "map_id": "P24339", "name": "cut7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753183", "map_id": "none", "name": "DDO oxidizes D-Asp to OA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_6810061", "map_id": "CHEBI:17364", "name": "D-Asp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389843", "map_id": "CHEBI:28938", "name": "NH4+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6810070", "map_id": "CHEBI:30744", "name": "OA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10753180", "map_id": "none", "name": "DDO:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10749687", "map_id": "none", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10749674", "map_id": "none", "name": "GCSH:DHLL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:50746", "map_id": "CHEBI:50746", "name": "CHEBI:50746", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9HDV9", "map_id": "Q9HDV9", "name": "gcv3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP19A11.01", "map_id": "SPBP19A11.01", "name": "gcv3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749657", "map_id": "Q9HDV9", "name": "gcv3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10749684", "map_id": "none", "name": "DLD dimer:2xFAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O00087", "map_id": "O00087", "name": "dld1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1002.09c", "map_id": "SPAC1002.09c", "name": "dld1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749682", "map_id": "none", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10749661", "map_id": "none", "name": "GCSH:SAMDLL", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:14949", "map_id": "CHEBI:14949", "name": "CHEBI:14949", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_200671", "map_id": "CHEBI:15635", "name": "THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5693984", "map_id": "CHEBI:12071", "name": "5,10-methylene-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5693978", "map_id": "CHEBI:16134", "name": "NH3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10749679", "map_id": "O14110", "name": "gcv1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPAC31G5.14", "map_id": "SPAC31G5.14", "name": "gcv1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750347", "map_id": "none", "name": "PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6784241", "map_id": "CHEBI:27391", "name": "1-pyrroline-3-hydroxy-5-carboxylate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10750344", "map_id": "none", "name": "PRODH2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "O74524", "map_id": "O74524", "name": "O74524", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738379", "map_id": "none", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389822", "map_id": "CHEBI:29805", "name": "glycolate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_389678", "map_id": "CHEBI:16891", "name": "glyoxylate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10738376", "map_id": "none", "name": "HAO1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10738367", "map_id": "none", "name": "glycine + O2 => glyoxylate + H2O2 + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_193446", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10738364", "map_id": "none", "name": "DAO dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "true" }, { "id": "reaction_10751187", "map_id": "none", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6793610", "map_id": "CHEBI:26833", "name": "S", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10751177", "map_id": "Q9HDV9", "name": "gcv3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6793613", "map_id": "CHEBI:17319", "name": "5dAde", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_379705", "map_id": "CHEBI:57844", "name": "L-Met", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10751184", "map_id": "none", "name": "LIAS:2(4Fe-4S)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O13642", "map_id": "O13642", "name": "lip5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC8D2.15", "map_id": "SPBC8D2.15", "name": "lip5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749672", "map_id": "none", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_159549", "map_id": "CHEBI:57305", "name": "Gly", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10749669", "map_id": "none", "name": "PXLP-K754-GLDC dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q09785", "map_id": "Q09785", "name": "gcv2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13G6.06c", "map_id": "SPAC13G6.06c", "name": "gcv2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750350", "map_id": "none", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6784236", "map_id": "CHEBI:32812", "name": "4-OH-L-Glu", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6784229", "map_id": "CHEBI:17742", "name": "HOG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10738382", "map_id": "none", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_389819", "map_id": "CHEBI:16995", "name": "OX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10751156", "map_id": "none", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10751146", "map_id": "none", "name": "DHs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O94681", "map_id": "O94681", "name": "kgd2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC776.15c", "map_id": "SPBC776.15c", "name": "kgd2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09171", "map_id": "Q09171", "name": "pdb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC30D10.13c", "map_id": "SPBC30D10.13c", "name": "pdb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17460", "map_id": "CHEBI:17460", "name": "CHEBI:17460", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59816", "map_id": "O59816", "name": "lat1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC794.07", "map_id": "SPCC794.07", "name": "lat1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10489", "map_id": "Q10489", "name": "pda1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26F1.03", "map_id": "SPAC26F1.03", "name": "pda1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74378", "map_id": "O74378", "name": "kgd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3H7.03c", "map_id": "SPBC3H7.03c", "name": "kgd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749659", "map_id": "Q9HDV9", "name": "gcv3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10751148", "map_id": "none", "name": "lipoylated DHs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10751153", "map_id": "O13629", "name": "aim22", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPBC17A3.09c", "map_id": "SPBC17A3.09c", "name": "aim22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749950", "map_id": "none", "name": "PXLP-K278-PHYKPL tetramer hydrolyses 5PHL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5696409", "map_id": "CHEBI:16752", "name": "5PHL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113556", "map_id": "CHEBI:17917", "name": "2AMAS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10749947", "map_id": "none", "name": "PXLP-K278-PHYKPL tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9US34", "map_id": "Q9US34", "name": "PXLP-K278-PHYKPL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1039.07c", "map_id": "SPAC1039.07c", "name": "PXLP-K278-PHYKPL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737977", "map_id": "none", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737973", "map_id": "Q9URZ5", "name": "vps1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737975", "map_id": "Q9URZ5", "name": "vps1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10737921", "map_id": "O14290", "name": "BCAP31(2-164)", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC9E9.04", "map_id": "SPAC9E9.04", "name": "BCAP31(2-164)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10754771", "map_id": "none", "name": "OMA1 hydrolyses OPA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10754747", "map_id": "none", "name": "Homologues of OPA1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_10754763", "map_id": "none", "name": "Homologues of OPA1(88-194)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_10754755", "map_id": "none", "name": "Homologues of OPA1(195-960)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "species_10754768", "map_id": "Q9P7G4", "name": "oma1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPAP14E8.04", "map_id": "SPAP14E8.04", "name": "oma1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10747046", "map_id": "none", "name": "BIRC2/3 (cIAP1/2) is autoubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737150", "map_id": "O14064", "name": "bir1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10747036", "map_id": "none", "name": "K48polyUb", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10747039", "map_id": "O14064", "name": "bir1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10752633", "map_id": "none", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10752617", "map_id": "none", "name": "Homologues of SEPT4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10752631", "map_id": "none", "name": "Homologues of SEPT4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10737755", "map_id": "none", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10737751", "map_id": "none", "name": "HMGB1/HMGB2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9USU7", "map_id": "Q9USU7", "name": "TFAM", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC28F2.11", "map_id": "SPBC28F2.11", "name": "TFAM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10241", "map_id": "Q10241", "name": "cmb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4G9.11c", "map_id": "SPAC4G9.11c", "name": "cmb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_29428", "map_id": "none", "name": "DNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10737753", "map_id": "none", "name": "HMGB1/HMGB2- bound chromatin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10737971", "map_id": "none", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10737945", "map_id": "none", "name": "Homologues of STK24(1-313)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10447", "map_id": "Q10447", "name": "ppk2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC12B10.14c", "map_id": "SPAC12B10.14c", "name": "ppk2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O75011", "map_id": "O75011", "name": "nak1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17F3.02", "map_id": "SPBC17F3.02", "name": "nak1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14047", "map_id": "O14047", "name": "ppk11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2C4.14c", "map_id": "SPAC2C4.14c", "name": "ppk11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14305", "map_id": "O14305", "name": "sid1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC9G1.09", "map_id": "SPAC9G1.09", "name": "sid1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10737969", "map_id": "none", "name": "Homologues of STK24(1-313)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10757583", "map_id": "none", "name": "Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757575", "map_id": "Q10356", "name": "hsp3106", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC22E12.03c", "map_id": "SPAC22E12.03c", "name": "hsp3106", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757579", "map_id": "none", "name": "Ub:UBE2N:UBE2V1:PRKN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757581", "map_id": "none", "name": "Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10356", "map_id": "Q10356", "name": "hsp3106", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757601", "map_id": "none", "name": "Parkin transfers Ub to misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757599", "map_id": "none", "name": "Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757649", "map_id": "none", "name": "Aggresome dissociates from dynein and microtubule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_18667", "compartment_display": "microtubule organizing center" }, { "id": "species_10757641", "map_id": "none", "name": "Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_18667", "compartment_display": "microtubule organizing center", "complex": "true" }, { "id": "O94518", "map_id": "O94518", "name": "dic1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.17c", "map_id": "SPBC646.17c", "name": "dic1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P56523", "map_id": "P56523", "name": "clr3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC800.03", "map_id": "SPBC800.03", "name": "clr3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757647", "map_id": "none", "name": "Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757627", "map_id": "none", "name": "Dynein complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757603", "map_id": "none", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757592", "map_id": "none", "name": "PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757631", "map_id": "none", "name": "PolyUb-Misfolded Proteins:HDAC6 bind dynein motor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757610", "map_id": "none", "name": "PolyUb-Misfolded Proteins:HDAC6", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757629", "map_id": "none", "name": "PolyUb-Misfolded Proteins:HDAC6:Dynein complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10730221", "map_id": "none", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_71112", "map_id": "CHEBI:15374", "name": "4aOH-BH4", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_71129", "map_id": "CHEBI:20680", "name": "qDHB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730218", "map_id": "none", "name": "PCBD1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42658", "map_id": "O42658", "name": "omt2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27D7.04", "map_id": "SPAC27D7.04", "name": "omt2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740374", "map_id": "none", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29502", "map_id": "CHEBI:58095", "name": "L-Phe", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_893599", "map_id": "CHEBI:29750", "name": "3IN-PYRA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10747288", "map_id": "none", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane" }, { "id": "species_10747126", "map_id": "none", "name": "LC3:PE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "species_10747279", "map_id": "none", "name": "LC3:PE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5683628", "compartment_display": "autophagosome membrane", "complex": "true" }, { "id": "species_10747286", "map_id": "none", "name": "UVRAG complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O60149", "map_id": "O60149", "name": "vps38", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC18H10.19", "map_id": "SPBC18H10.19", "name": "vps38", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87117", "map_id": "P87117", "name": "phospho-atg6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC20G8.10c", "map_id": "SPAC20G8.10c", "name": "phospho-atg6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10747194", "map_id": "none", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747189", "map_id": "none", "name": "LC3:CysO572-ATG7:ATG7:ATG3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O43035", "map_id": "O43035", "name": "atg3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B9.06c", "map_id": "SPBC3B9.06c", "name": "atg3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747191", "map_id": "none", "name": "LC3:CysO263-ATG3:ATG7 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746800", "map_id": "none", "name": "Thr-180 of ULK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746707", "map_id": "none", "name": "p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14261", "map_id": "O14261", "name": "taf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC7D4.04", "map_id": "SPAC7D4.04", "name": "taf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13978", "map_id": "O13978", "name": "mug66", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC25H1.03", "map_id": "SPAC25H1.03", "name": "mug66", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O36019", "map_id": "O36019", "name": "atg13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4F10.07c", "map_id": "SPAC4F10.07c", "name": "atg13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746797", "map_id": "none", "name": "p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757752", "map_id": "none", "name": "ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10757718", "map_id": "none", "name": "ATM dimer:p-PEX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "species_10757740", "map_id": "none", "name": "ATM dimer:Ub-p-PEX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10747085", "map_id": "none", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747081", "map_id": "none", "name": "WIPI1,WIPI2,(WDR45,WDR45B)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P6N1", "map_id": "Q9P6N1", "name": "mug179", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC823.16c", "map_id": "SPAC823.16c", "name": "mug179", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9HDZ7", "map_id": "Q9HDZ7", "name": "atg18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC589.07c", "map_id": "SPAC589.07c", "name": "atg18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P3W2", "map_id": "Q9P3W2", "name": "hsv2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC458.06", "map_id": "SPAC458.06", "name": "hsv2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5693050", "map_id": "CHEBI:17283", "name": "PI3P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "false" }, { "id": "species_10747083", "map_id": "none", "name": "WIPI1,WIPI2,(WDR45,WDR45B):PI3P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "species_1629751", "map_id": "CHEBI:17283", "name": "PI3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10756472", "map_id": "none", "name": "LC3 binds the autophagosome membrane Atg5-Atg12 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_21994", "compartment_display": "phagocytic vesicle" }, { "id": "species_10745146", "map_id": "none", "name": "ATG5:ATG12", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "Q9US24", "map_id": "Q9US24", "name": "atg12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1783.06c", "map_id": "SPAC1783.06c", "name": "atg12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74971", "map_id": "O74971", "name": "atg5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4B4.10c", "map_id": "SPBC4B4.10c", "name": "atg5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756468", "map_id": "none", "name": "p-S17-FUNDC1:LC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "O14020", "map_id": "O14020", "name": "phospho-p-S17-FUNDC1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC29A4.17c", "map_id": "SPAC29A4.17c", "name": "phospho-p-S17-FUNDC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756470", "map_id": "none", "name": "p-S17-FUNDC1:LC3:ATG5:ATG12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10747385", "map_id": "none", "name": "ATG10 dissociates from ATG12:ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747383", "map_id": "none", "name": "ATG10:GlyK130-ATG5:ATG12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UTD5", "map_id": "Q9UTD5", "name": "ATG10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC227.04", "map_id": "SPAC227.04", "name": "ATG10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747381", "map_id": "Q9UTD5", "name": "ATG10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10747137", "map_id": "none", "name": "GlyK130-ATG5:ATG12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756095", "map_id": "none", "name": "FUNDC1 is phosphorylated by CK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756090", "map_id": "O14020", "name": "FUNDC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10756093", "map_id": "O14020", "name": "phospho-p-S13-FUNDC1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10746802", "map_id": "none", "name": "p-AMPK:AMP binds the ULK complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746699", "map_id": "none", "name": "ULK1:ATG13:RB1CC1:ATG101", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746701", "map_id": "none", "name": "p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10747172", "map_id": "none", "name": "ULK complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747055", "map_id": "none", "name": "p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10742300", "map_id": "none", "name": "p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10747484", "map_id": "none", "name": "ATG10 transfers ATG12 from ATG10 to ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747214", "map_id": "none", "name": "ATG12:GlyK166-ATG10:ATG5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10747216", "map_id": "none", "name": "ATG10:ATG12 binds ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747210", "map_id": "none", "name": "ATG12:GlyK166-ATG10", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10747212", "map_id": "O74971", "name": "atg5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10757705", "map_id": "none", "name": "ATM binds PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757061", "map_id": "O94325", "name": "pex5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10757701", "map_id": "O74630", "name": "tel1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10757703", "map_id": "none", "name": "ATM:PEX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10747180", "map_id": "none", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747176", "map_id": "none", "name": "ATG7 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10747132", "map_id": "Q9US24", "name": "atg12", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10747178", "map_id": "none", "name": "ATG12:ATG7 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756108", "map_id": "none", "name": "FUNDC1 is phosphorylated by ULK1 at Ser17", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10756105", "map_id": "O14020", "name": "phospho-p-S17-FUNDC1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10756097", "map_id": "Q9Y7T4", "name": "atg1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10746710", "map_id": "none", "name": "AMPK (complex) phosphorylates ULK1 (complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10757750", "map_id": "none", "name": "ATM:PEX5 translocates from cytosol to peroxisomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757709", "map_id": "none", "name": "ATM:PEX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10757720", "map_id": "none", "name": "ATM dimer:PEX5 phosphorylates PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10757711", "map_id": "none", "name": "ATM dimer:PEX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10747174", "map_id": "none", "name": "Beclin-1 complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742261", "map_id": "none", "name": "BECN1 complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42862", "map_id": "O42862", "name": "atg14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC25A8.02", "map_id": "SPAC25A8.02", "name": "atg14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747165", "map_id": "none", "name": "Beclin-1 complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10747146", "map_id": "none", "name": "ATG16L1 complex transfers LC3 from ATG3 to PE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747124", "map_id": "none", "name": "CysO263-ATG3:LC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_5681998", "map_id": "CHEBI:16038", "name": "PE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "false" }, { "id": "species_10747128", "map_id": "O43035", "name": "atg3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10747143", "map_id": "none", "name": "ATG16L1 complex:WIPI2:PI(3,5)P2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "reaction_10756099", "map_id": "none", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10746691", "map_id": "Q9Y7T4", "name": "atg1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10747268", "map_id": "none", "name": "The phagophore extends from the PIP3-enriched structure", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10746809", "map_id": "none", "name": "ATG14:PIK3C3:PIK3R4:p-S15-BECN1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10747259", "map_id": "none", "name": "ATG14:PIK3C3:PIK3R4:p-S15-BECN1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "true" }, { "id": "species_10747264", "map_id": "O74312", "name": "atg9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5679192", "compartment_display": "phagophore assembly site membrane", "complex": "false" }, { "id": "SPBC15D4.07c", "map_id": "SPBC15D4.07c", "name": "atg9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10747170", "map_id": "none", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742434", "map_id": "O13819", "name": "MTMR3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10747218", "map_id": "none", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747110", "map_id": "O94272", "name": "atg8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10747187", "map_id": "none", "name": "LC3:CysO572-ATG7:ATG7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10747486", "map_id": "none", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10757748", "map_id": "none", "name": "MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10747112", "map_id": "O94272", "name": "atg8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10757744", "map_id": "none", "name": "ATM dimer:Ub-p-PEX5:SQSTM1:NBR1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "Q9P792", "map_id": "Q9P792", "name": "Q9P792", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP35G2.11c", "map_id": "SPBP35G2.11c", "name": "Q9P792", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757746", "map_id": "none", "name": "ATM dimer:Ub-p-PEX5:SQSTM1:NBR1:MAP1LC3B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10756474", "map_id": "none", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10747167", "map_id": "none", "name": "ULK1 phosphorylates Beclin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10747524", "map_id": "none", "name": "ULK1 is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747522", "map_id": "none", "name": "p-S758-ULK1:ATG13:RB1CC1:ATG101", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10747431", "map_id": "none", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10757731", "map_id": "none", "name": "ATM:PEX5 binds ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10757707", "map_id": "O74630", "name": "tel1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10746812", "map_id": "none", "name": "Beclin-1 complex phosphorylates PtdIns", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10747429", "map_id": "none", "name": "ATG12:ATG7:CysO572-ATG7 binds ATG10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747425", "map_id": "none", "name": "ATG12:ATG7:CysO572-ATG7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10747427", "map_id": "none", "name": "ATG12:ATG7:CysO572-ATG7:ATG10", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742303", "map_id": "none", "name": "ULK1 phosphorylates AMBRA1:BECN1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742263", "map_id": "none", "name": "AMBRA1:DYNLL1,DYNLL2:BECN1 complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10742269", "map_id": "none", "name": "BECN1 complex:p-AMBRA1:DYNLL1,DYNLL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10747058", "map_id": "none", "name": "ULK1 phosphorylates ATG13 and RB1CC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10757729", "map_id": "none", "name": "NBR1 binds MAP1LC3B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10757725", "map_id": "Q9P792", "name": "Q9P792", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "false" }, { "id": "species_10757727", "map_id": "none", "name": "NBR1:MAP1LC3B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10756986", "map_id": "none", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10733817", "map_id": "none", "name": "Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733776", "map_id": "P10506", "name": "phospho-byr1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10757664", "map_id": "none", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9647934", "map_id": "pubchem.compound:45100481", "name": "Palmostatin B", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10737221", "map_id": "none", "name": "LYPLA1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42881", "map_id": "O42881", "name": "LYPLA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC8E11.04c", "map_id": "SPAC8E11.04c", "name": "LYPLA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757662", "map_id": "none", "name": "Palmostatin B:LYPLA1 dimer, ABHD17A,B,C", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746851", "map_id": "none", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10746846", "map_id": "none", "name": "IL17RD:p-2S MAP2Ks:MAPKs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10746848", "map_id": "none", "name": "IL17RD:p-2S MAP2Ks:p-T,Y MAPKs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10733772", "map_id": "none", "name": "MAP2K1 binds MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733756", "map_id": "P10506", "name": "phospho-byr1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10733768", "map_id": "none", "name": "Homologues of MAPK3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757671", "map_id": "none", "name": "USP17L2 deubiquitinates RCE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10757666", "map_id": "O94448", "name": "PolyUb-RCE1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC1687.02", "map_id": "SPAC1687.02", "name": "RCE1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757668", "map_id": "O94448", "name": "RCE1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10749260", "map_id": "none", "name": "PolyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10749999", "map_id": "O74442", "name": "ubp16", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC1682.12c", "map_id": "SPCC1682.12c", "name": "ubp16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746325", "map_id": "none", "name": "Autophosphorylation of PAK1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746306", "map_id": "none", "name": "CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10746322", "map_id": "none", "name": "p-S,T-PAK1,2,3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757660", "map_id": "none", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9653479", "map_id": "none", "name": "FNTB inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=6531", "map_id": "LigandDisplayForward?ligandId=6531", "name": "LigandDisplayForward?ligandId=6531", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8025", "map_id": "LigandDisplayForward?ligandId=8025", "name": "LigandDisplayForward?ligandId=8025", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8024", "map_id": "LigandDisplayForward?ligandId=8024", "name": "LigandDisplayForward?ligandId=8024", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "pubchem.compound:216453", "map_id": "pubchem.compound:216453", "name": "pubchem.compound:216453", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8028", "map_id": "LigandDisplayForward?ligandId=8028", "name": "LigandDisplayForward?ligandId=8028", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8026", "map_id": "LigandDisplayForward?ligandId=8026", "name": "LigandDisplayForward?ligandId=8026", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8030", "map_id": "LigandDisplayForward?ligandId=8030", "name": "LigandDisplayForward?ligandId=8030", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757656", "map_id": "none", "name": "FNTA:FNTB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13782", "map_id": "O13782", "name": "cpp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17G6.04c", "map_id": "SPAC17G6.04c", "name": "cpp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60052", "map_id": "O60052", "name": "cwp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB1A10.04c", "map_id": "SPAPB1A10.04c", "name": "cwp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757658", "map_id": "none", "name": "FNTA:FNTB:FTase inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746861", "map_id": "none", "name": "Phosphorylated MAPKs translocate into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10733782", "map_id": "none", "name": "MAP2K2 binds MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733778", "map_id": "P27638", "name": "spk1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10733815", "map_id": "none", "name": "Dissociation of p-T,Y-MAPK3:MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733792", "map_id": "none", "name": "Homologues of p-T202,Y204-MAPK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10754546", "map_id": "none", "name": "PP2A methylation by LCMT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10754531", "map_id": "none", "name": "PP2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q12702", "map_id": "Q12702", "name": "pab1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754538", "map_id": "none", "name": "MeL-PP2A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10754543", "map_id": "O94257", "name": "ppm1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBP8B7.08c", "map_id": "SPBP8B7.08c", "name": "ppm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735452", "map_id": "none", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10735448", "map_id": "none", "name": "CDC25", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10735450", "map_id": "none", "name": "CDC25", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10754554", "map_id": "none", "name": "PP2A demethylation by PPME1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_8857797", "map_id": "CHEBI:17790", "name": "methanol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10754551", "map_id": "Q9P7D2", "name": "ppe1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBP4H10.17c", "map_id": "SPBP4H10.17c", "name": "ppe1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734633", "map_id": "none", "name": "Activation of Cdc25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734625", "map_id": "P06652", "name": "cdc25", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734628", "map_id": "P06652", "name": "phospho-cdc25", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734630", "map_id": "P50528", "name": "phospho-plo1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10735444", "map_id": "none", "name": "Translocation of active Cdc25C to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10735442", "map_id": "P06652", "name": "phospho-cdc25", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10735440", "map_id": "none", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10735436", "map_id": "P06652", "name": "cdc25", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10735438", "map_id": "P06652", "name": "cdc25", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10743753", "map_id": "none", "name": "Cytosolic PLK1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10734775", "map_id": "none", "name": "Inactivation of Myt1 kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734770", "map_id": "P07527", "name": "wee1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10734773", "map_id": "P07527", "name": "phospho-wee1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10743650", "map_id": "none", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743587", "map_id": "none", "name": "SUMO1:UBA2:SAE1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O42939", "map_id": "O42939", "name": "uba2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16H5.03c", "map_id": "SPBC16H5.03c", "name": "uba2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79064", "map_id": "P79064", "name": "rad31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4C5.04", "map_id": "SPAC4C5.04", "name": "rad31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743572", "map_id": "none", "name": "UBA2:SAE1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10743604", "map_id": "none", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743592", "map_id": "O13351", "name": "pmt3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10743577", "map_id": "O13351", "name": "pmt3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10743597", "map_id": "O42957", "name": "ulp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC19G7.09", "map_id": "SPBC19G7.09", "name": "ulp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743590", "map_id": "none", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10749697", "map_id": "none", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5694074", "map_id": "CHEBI:17158", "name": "MGXL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5694130", "map_id": "CHEBI:15694", "name": "(R)-S-LGSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10749694", "map_id": "none", "name": "GLO1 dimer:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09751", "map_id": "Q09751", "name": "glo1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC12C2.12c", "map_id": "SPBC12C2.12c", "name": "glo1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739914", "map_id": "none", "name": "isocitrate <=> citrate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29938", "map_id": "CHEBI:151", "name": "ISCIT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10730103", "map_id": "O13966", "name": "ACO2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPAC24C9.06c", "map_id": "SPAC24C9.06c", "name": "ACO2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737284", "map_id": "none", "name": "PDK isoforms phosphorylate lipo-PDH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10730323", "map_id": "none", "name": "lipo-PDH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10737268", "map_id": "none", "name": "p-lipo-PDH", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10737273", "map_id": "Q9P6P9", "name": "pkp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPAC644.11c", "map_id": "SPAC644.11c", "name": "pkp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10737282", "map_id": "none", "name": "DCA:PDK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_9010792", "map_id": "LigandDisplayForward?ligandId=4518", "name": "DCA", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "Q9P6P9", "map_id": "Q9P6P9", "name": "pkp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730326", "map_id": "none", "name": "lipo-PDH decarboxylates PYR to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10756610", "map_id": "none", "name": "DCA binds PDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10737275", "map_id": "Q9P6P9", "name": "pkp1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10735422", "map_id": "none", "name": "ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_73663", "map_id": "CHEBI:46245", "name": "CoQ", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10735411", "map_id": "none", "name": "ETF:FADH2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P78790", "map_id": "P78790", "name": "P78790", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27D7.06", "map_id": "SPAC27D7.06", "name": "P78790", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UTH2", "map_id": "Q9UTH2", "name": "ETFB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1805.02c", "map_id": "SPAC1805.02c", "name": "ETFB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_76633", "map_id": "CHEBI:17976", "name": "QH2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10735409", "map_id": "none", "name": "ETF:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10735419", "map_id": "P87111", "name": "ETFDH", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPAC20G8.04c", "map_id": "SPAC20G8.04c", "name": "ETFDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730165", "map_id": "none", "name": "Succinate <=> Fumarate (with FAD redox reaction on enzyme)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113588", "map_id": "CHEBI:18012", "name": "FUMA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10730162", "map_id": "none", "name": "SDH complex (ox.)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q9P7X0", "map_id": "Q9P7X0", "name": "sdh4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP23A10.16", "map_id": "SPBP23A10.16", "name": "sdh4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UTJ7", "map_id": "Q9UTJ7", "name": "sdh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1556.02c", "map_id": "SPAC1556.02c", "name": "sdh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74882", "map_id": "O74882", "name": "sdh3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC330.12c", "map_id": "SPCC330.12c", "name": "sdh3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P21911", "map_id": "P21911", "name": "sdh2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC140.01", "map_id": "SPAC140.01", "name": "sdh2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730116", "map_id": "none", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10730113", "map_id": "none", "name": "CS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q10306", "map_id": "Q10306", "name": "cit1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6C3.04", "map_id": "SPAC6C3.04", "name": "cit1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757797", "map_id": "none", "name": "PM20D1 hydrolyzes oleoyl-phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9673044", "map_id": "CHEBI:134020", "name": "oleoyl-Phe", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_351993", "map_id": "CHEBI:58095", "name": "L-Phe", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_9673048", "map_id": "CHEBI:30823", "name": "oleate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10757792", "map_id": "O13968", "name": "PM20D1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "SPAC24C9.08", "map_id": "SPAC24C9.08", "name": "PM20D1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10752715", "map_id": "none", "name": "LDHAL6B reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6807616", "map_id": "CHEBI:422", "name": "LACT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10752712", "map_id": "Q9P7P7", "name": "LDHAL6B", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPAC186.08c", "map_id": "SPAC186.08c", "name": "LDHAL6B", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750305", "map_id": "none", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29708", "map_id": "CHEBI:422", "name": "LACT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10750302", "map_id": "none", "name": "HAGH-2:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UT36", "map_id": "Q9UT36", "name": "HAGH-2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC824.07", "map_id": "SPAC824.07", "name": "HAGH-2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730098", "map_id": "none", "name": "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10730095", "map_id": "none", "name": "IDH3 complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O13696", "map_id": "O13696", "name": "idh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC11G7.03", "map_id": "SPAC11G7.03", "name": "idh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USP8", "map_id": "Q9USP8", "name": "idh2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC902.05c", "map_id": "SPBC902.05c", "name": "idh2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730607", "map_id": "none", "name": "LDH tetramer reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729885", "map_id": "none", "name": "LDH tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P7P7", "map_id": "Q9P7P7", "name": "LDHAL6B", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735414", "map_id": "none", "name": "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10739916", "map_id": "none", "name": "(S)-Malate <=> Fumarate + H2O", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10730133", "map_id": "none", "name": "FH tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O94552", "map_id": "O94552", "name": "fum1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC18.18c", "map_id": "SPCC18.18c", "name": "fum1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756661", "map_id": "none", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9012375", "map_id": "CHEBI:15361", "name": "PYR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10745156", "map_id": "Q9P544", "name": "VDAC1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "SPAC1635.01", "map_id": "SPAC1635.01", "name": "VDAC1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730180", "map_id": "none", "name": "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70958", "map_id": "CHEBI:57292", "name": "SUCC-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10730177", "map_id": "none", "name": "SUCLA2:SUCLG1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O13750", "map_id": "O13750", "name": "SUCLG1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC16E8.17c", "map_id": "SPAC16E8.17c", "name": "SUCLG1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94415", "map_id": "O94415", "name": "SUCLA2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1620.08", "map_id": "SPCC1620.08", "name": "SUCLA2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735047", "map_id": "none", "name": "Electron transfer from ubiquinol to cytochrome c of complex III", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10735044", "map_id": "none", "name": "Ubiquinol-cytochrome c reductase", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "Q9P7X1", "map_id": "Q9P7X1", "name": "qcr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP23A10.15c", "map_id": "SPBP23A10.15c", "name": "qcr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09154", "map_id": "Q09154", "name": "rip1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16H5.06", "map_id": "SPBC16H5.06", "name": "rip1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42932", "map_id": "O42932", "name": "qcr6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16C6.08c", "map_id": "SPBC16C6.08c", "name": "qcr6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P05501", "map_id": "P05501", "name": "cob", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPMIT.05", "map_id": "SPMIT.05", "name": "cob", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P50523", "map_id": "P50523", "name": "qcr8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1782.07", "map_id": "SPAC1782.07", "name": "qcr8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74533", "map_id": "O74533", "name": "qcr7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC737.02c", "map_id": "SPCC737.02c", "name": "qcr7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59680", "map_id": "O59680", "name": "cyt1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29A3.18", "map_id": "SPBC29A3.18", "name": "cyt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94745", "map_id": "O94745", "name": "mas2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC18E5.12c", "map_id": "SPBC18E5.12c", "name": "mas2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74433", "map_id": "O74433", "name": "qcr9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1682.01", "map_id": "SPCC1682.01", "name": "qcr9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729888", "map_id": "none", "name": "LDH tetramer oxidises LACT to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10756645", "map_id": "none", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10756642", "map_id": "none", "name": "FAHD1:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q9P7L4", "map_id": "Q9P7L4", "name": "FAHD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC21C3.09c", "map_id": "SPBC21C3.09c", "name": "FAHD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730328", "map_id": "none", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10730208", "map_id": "none", "name": "lipo-aKGDH", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10740353", "map_id": "none", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_879997", "map_id": "CHEBI:32796", "name": "2HG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10740350", "map_id": "Q9C1X2", "name": "D2HGDH", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPBC713.03", "map_id": "SPBC713.03", "name": "D2HGDH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_880067", "map_id": "CHEBI:29105", "name": "Zn2+", "type": "catalyst", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10757795", "map_id": "none", "name": "PM20D1 transforms oleoyl-phe from oleate and phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10736322", "map_id": "none", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194634", "map_id": "CHEBI:16521", "name": "LAN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_194644", "map_id": "CHEBI:17813", "name": "4,4DMCHtOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_29460", "map_id": "CHEBI:30751", "name": "HCOOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736319", "map_id": "Q09736", "name": "erg11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC13A11.02c", "map_id": "SPAC13A11.02c", "name": "erg11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742192", "map_id": "none", "name": "Alpha-galactosidase A removes a terminal galactose from alpha-D-galactoside oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_1605716", "map_id": "CHEBI:18313", "name": "Gb3Cer", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_1605715", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_1605601", "map_id": "CHEBI:17950", "name": "LacCer", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_1605637", "map_id": "CHEBI:28061", "name": "Gal", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10742189", "map_id": "none", "name": "GLA dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10742202", "map_id": "none", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_429776", "map_id": "CHEBI:17636", "name": "SPHM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_429807", "map_id": "CHEBI:17761", "name": "CERA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1610735", "map_id": "CHEBI:18132", "name": "ChoP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10742199", "map_id": "none", "name": "SMPD2,3:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "O74369", "map_id": "O74369", "name": "css1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC32F12.01c", "map_id": "SPBC32F12.01c", "name": "css1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742308", "map_id": "none", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10742305", "map_id": "O94323", "name": "ENPP7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10745892", "map_id": "none", "name": "RDH5,RDH11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30927", "map_id": "CHEBI:16302", "name": "11cROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_32737", "map_id": "CHEBI:16066", "name": "11cRAL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745889", "map_id": "none", "name": "Homologues of RDH5(24-318)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10745878", "map_id": "none", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_975622", "map_id": "CHEBI:17898", "name": "atRAL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5334816", "map_id": "CHEBI:15367", "name": "atRA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745875", "map_id": "none", "name": "ALDH1A1,2,3 tetramers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14293", "map_id": "O14293", "name": "ALDH1A3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC9E9.09c", "map_id": "SPAC9E9.09c", "name": "ALDH1A3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745907", "map_id": "none", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_975599", "map_id": "CHEBI:17336", "name": "atROL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745904", "map_id": "none", "name": "Homologues of RDH14", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O74959", "map_id": "O74959", "name": "RDH14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC736.13", "map_id": "SPCC736.13", "name": "RDH14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13822", "map_id": "O13822", "name": "RDH14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745865", "map_id": "none", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10745862", "map_id": "none", "name": "RDH10,16,DHRS9,RDHE2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10746047", "map_id": "none", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10745883", "map_id": "none", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10745880", "map_id": "none", "name": "ADH1A,1C,4 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10737563", "map_id": "none", "name": "PRC2 trimethylates histone H3 at lysine-27", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10737551", "map_id": "none", "name": "PRC2:Chromatin", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10737560", "map_id": "none", "name": "PRC2:Chromatin (H3K27me3)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745441", "map_id": "none", "name": "TDG excises 5-formylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5221062", "map_id": "none", "name": "DNA containing 5-fC", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10733889", "map_id": "none", "name": "TDG:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5221065", "map_id": "CHEBI:76794", "name": "5-fC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10745443", "map_id": "none", "name": "TDG excises 5-carboxylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5220996", "map_id": "none", "name": "DNA containing 5-caC", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_5221064", "map_id": "CHEBI:76793", "name": "5-caC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10749501", "map_id": "none", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735397", "map_id": "none", "name": "K63polyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10735395", "map_id": "none", "name": "K63-Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729170", "map_id": "P41878", "name": "rpn11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10749588", "map_id": "none", "name": "STAMBP binds STAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10749579", "map_id": "none", "name": "Homologues of STAM", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74749", "map_id": "O74749", "name": "hse1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1734.08", "map_id": "SPBC1734.08", "name": "hse1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94478", "map_id": "O94478", "name": "mug137", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1919.11", "map_id": "SPCC1919.11", "name": "mug137", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749584", "map_id": "Q9P371", "name": "sst2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC19B12.10", "map_id": "SPAC19B12.10", "name": "sst2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749586", "map_id": "none", "name": "STAMBP:STAM", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P371", "map_id": "Q9P371", "name": "sst2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749982", "map_id": "none", "name": "STAMBPL1 is a deubiquitinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10749979", "map_id": "Q9P371", "name": "sst2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736864", "map_id": "none", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_197965", "map_id": "CHEBI:27470", "name": "FOLA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_200716", "map_id": "CHEBI:27470", "name": "FOLA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10736856", "map_id": "none", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_200739", "map_id": "CHEBI:60473", "name": "5,10-methylene-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_200640", "map_id": "CHEBI:65049", "name": "5,10-methenyl-THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736853", "map_id": "none", "name": "MTHFD1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q8WZJ7", "map_id": "Q8WZJ7", "name": "MTHFD1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC839.16", "map_id": "SPBC839.16", "name": "MTHFD1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744081", "map_id": "none", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743659", "map_id": "none", "name": "4x(Btn-PC:Mn2+)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10743759", "map_id": "none", "name": "4x(Btn-PC:Mn2+)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10749713", "map_id": "none", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_379732", "map_id": "CHEBI:33384", "name": "L-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10749710", "map_id": "none", "name": "PXLP-K280-SHMT2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "O13972", "map_id": "O13972", "name": "PXLP-K280-SHMT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC24C9.12c", "map_id": "SPAC24C9.12c", "name": "PXLP-K280-SHMT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736843", "map_id": "none", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_200492", "map_id": "CHEBI:15763", "name": "NAMN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_200499", "map_id": "CHEBI:18304", "name": "NAAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10736840", "map_id": "none", "name": "6xNMNAT1:6xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9UT53", "map_id": "Q9UT53", "name": "NMNAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC806.06c", "map_id": "SPAC806.06c", "name": "NMNAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740902", "map_id": "none", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_965053", "map_id": "CHEBI:16709", "name": "PDX", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_964952", "map_id": "CHEBI:28803", "name": "PDXP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740897", "map_id": "none", "name": "2xPDXK:2xZn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10736380", "map_id": "none", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196767", "map_id": "CHEBI:16858", "name": "PPANT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196778", "map_id": "CHEBI:15468", "name": "DP-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736377", "map_id": "Q10350", "name": "COASY", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "SPAC1F12.08", "map_id": "SPAC1F12.08", "name": "COASY", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736449", "map_id": "none", "name": "FPGS-2 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_197969", "map_id": "CHEBI:28624", "name": "THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736446", "map_id": "O74742", "name": "met7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC1709.17", "map_id": "SPBC1709.17", "name": "met7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755126", "map_id": "none", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8869377", "map_id": "CHEBI:15927", "name": "NR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8869353", "map_id": "CHEBI:14649", "name": "NMN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10755112", "map_id": "Q9C0W1", "name": "nrk1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBP22H7.06", "map_id": "SPBP22H7.06", "name": "nrk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743762", "map_id": "none", "name": "ABCC1 transports cytosolic Cbl to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_3000241", "map_id": "CHEBI:28911", "name": "Cbl", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_3000125", "map_id": "CHEBI:28911", "name": "Cbl", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10736897", "map_id": "none", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111353", "map_id": "CHEBI:28010", "name": "10-formyl-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736901", "map_id": "none", "name": "SLC25A32 transports THF from mitochondrial matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10736884", "map_id": "O13660", "name": "SLC25A32", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPBC27B12.09c", "map_id": "SPBC27B12.09c", "name": "SLC25A32", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736383", "map_id": "none", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10740904", "map_id": "none", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_965131", "map_id": "CHEBI:17310", "name": "PXL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29390", "map_id": "CHEBI:18405", "name": "PXLP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10744750", "map_id": "none", "name": "HLCS biotinylates ACACB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744748", "map_id": "none", "name": "ACACB:2Mn2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10736807", "map_id": "none", "name": "Btn-ACACB:2Mn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10743664", "map_id": "O14353", "name": "bpl1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC30D10.07c", "map_id": "SPBC30D10.07c", "name": "bpl1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736866", "map_id": "none", "name": "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_200736", "map_id": "CHEBI:33384", "name": "L-Ser", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10740888", "map_id": "none", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740872", "map_id": "none", "name": "MOCS3:Zn2+ (red.)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09810", "map_id": "Q09810", "name": "uba4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2G11.10c", "map_id": "SPAC2G11.10c", "name": "uba4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740877", "map_id": "none", "name": "MOCS3-S-S(1-):Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10740885", "map_id": "none", "name": "PXLP-K258-NFS1-2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10740914", "map_id": "none", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740911", "map_id": "none", "name": "2xPNPO:2xFMN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UTQ1", "map_id": "Q9UTQ1", "name": "PNPO", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1093.02", "map_id": "SPAC1093.02", "name": "PNPO", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736894", "map_id": "none", "name": "Mitochondrial FPGS-1 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_200679", "map_id": "CHEBI:28624", "name": "THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10736891", "map_id": "O74742", "name": "met7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10736836", "map_id": "none", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_8938083", "map_id": "CHEBI:15763", "name": "NAMN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_8938090", "map_id": "CHEBI:18304", "name": "NAAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10736833", "map_id": "none", "name": "4xNMNAT3:4xMg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10740900", "map_id": "none", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_964945", "map_id": "CHEBI:16410", "name": "PXA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_965146", "map_id": "CHEBI:18335", "name": "PXAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736905", "map_id": "none", "name": "SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736907", "map_id": "none", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10752500", "map_id": "none", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5389850", "map_id": "CHEBI:15637", "name": "10-formyl-THF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_6801451", "map_id": "CHEBI:30751", "name": "HCOOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10750054", "map_id": "none", "name": "MTHFD1L dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O43007", "map_id": "O43007", "name": "ade9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2G2.08", "map_id": "SPBC2G2.08", "name": "ade9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736658", "map_id": "none", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736644", "map_id": "none", "name": "CYB5A:heme", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "Q9USM6", "map_id": "Q9USM6", "name": "oca8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC16A11.10c", "map_id": "SPCC16A11.10c", "name": "oca8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1497805", "map_id": "CHEBI:59513", "name": "Asc.-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_198816", "map_id": "CHEBI:38290", "name": "AscH-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736642", "map_id": "none", "name": "CYB5A:ferriheme", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10736899", "map_id": "none", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10743673", "map_id": "none", "name": "HLCS biotinylates ACACA:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743671", "map_id": "none", "name": "ACACA:2Mn2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10733321", "map_id": "none", "name": "Btn-ACACA:2Mn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10736431", "map_id": "none", "name": "NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_197220", "map_id": "CHEBI:15763", "name": "NAMN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_197256", "map_id": "CHEBI:18304", "name": "NAAD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736428", "map_id": "none", "name": "NMNAT2:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10736372", "map_id": "none", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196786", "map_id": "CHEBI:15905", "name": "PPanK", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196834", "map_id": "CHEBI:15769", "name": "PPC", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736369", "map_id": "none", "name": "2xPPCS", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9USK7", "map_id": "Q9USK7", "name": "PPCS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC4B3.18", "map_id": "SPCC4B3.18", "name": "PPCS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740916", "map_id": "none", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736441", "map_id": "none", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736438", "map_id": "none", "name": "NADSYN1 hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74940", "map_id": "O74940", "name": "NADSYN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC553.02", "map_id": "SPCC553.02", "name": "NADSYN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743667", "map_id": "none", "name": "HLCS biotinylates PC:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743654", "map_id": "none", "name": "4x(PC:Mn2+)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10736903", "map_id": "none", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10752956", "map_id": "none", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10752953", "map_id": "none", "name": "ALDH1L1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10752498", "map_id": "none", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6803257", "map_id": "CHEBI:63907", "name": "5-formyl-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10752495", "map_id": "Q9P7W2", "name": "MTHFS", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC1703.08c", "map_id": "SPBC1703.08c", "name": "MTHFS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757959", "map_id": "none", "name": "DHFR dimer reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757956", "map_id": "none", "name": "DHFR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P36591", "map_id": "P36591", "name": "dfr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1223.08c", "map_id": "SPCC1223.08c", "name": "dfr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755120", "map_id": "none", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8869365", "map_id": "CHEBI:58527", "name": "NAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10755117", "map_id": "Q9C0W1", "name": "nrk1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10750057", "map_id": "none", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10736457", "map_id": "none", "name": "DHFR2 reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736454", "map_id": "P36591", "name": "dfr1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10755856", "map_id": "none", "name": "NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736889", "map_id": "none", "name": "FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_200665", "map_id": "CHEBI:15641", "name": "5-methyl-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_174404", "map_id": "CHEBI:63907", "name": "5-methyl-THFPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736421", "map_id": "none", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736418", "map_id": "none", "name": "NADK:Zn2+ tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13863", "map_id": "O13863", "name": "NADK", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1B1.02c", "map_id": "SPAC1B1.02c", "name": "NADK", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755115", "map_id": "none", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736655", "map_id": "none", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736652", "map_id": "none", "name": "CYB5R3:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10736869", "map_id": "none", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10755480", "map_id": "none", "name": "SLC25A19 transports ThDP from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_8878387", "map_id": "CHEBI:58937", "name": "ThDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10755477", "map_id": "O94370", "name": "SLC25A19", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPBC1604.04", "map_id": "SPBC1604.04", "name": "SLC25A19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755123", "map_id": "none", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736459", "map_id": "none", "name": "DHF is reduced to tetrahydrofolate (THF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736879", "map_id": "none", "name": "MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736876", "map_id": "none", "name": "MTHFR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10258", "map_id": "Q10258", "name": "met9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC56F8.10", "map_id": "SPAC56F8.10", "name": "met9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10752948", "map_id": "none", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_6808499", "map_id": "CHEBI:28010", "name": "10-formyl-THFPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10752945", "map_id": "none", "name": "ADH1L2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10736666", "map_id": "none", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_10736663", "map_id": "O13805", "name": "SLC25A16", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPAC17H9.08", "map_id": "SPAC17H9.08", "name": "SLC25A16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736327", "map_id": "none", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194633", "map_id": "CHEBI:18364", "name": "14DMLANOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10736324", "map_id": "Q09195", "name": "erg24", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10736094", "map_id": "none", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191374", "map_id": "CHEBI:43074", "name": "bHMG-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191424", "map_id": "CHEBI:17710", "name": "MVA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736091", "map_id": "none", "name": "HMGCR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q10283", "map_id": "Q10283", "name": "hmg1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC162.09c", "map_id": "SPCC162.09c", "name": "hmg1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736314", "map_id": "none", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_194681", "map_id": "CHEBI:17813", "name": "4,4DMCHtOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194688", "map_id": "CHEBI:15378", "name": "H+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194725", "map_id": "CHEBI:16474", "name": "NADPH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194704", "map_id": "CHEBI:18364", "name": "14DMLANOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_194668", "map_id": "CHEBI:18009", "name": "NADP+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10736311", "map_id": "Q09195", "name": "erg24", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "reaction_10736304", "map_id": "none", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194735", "map_id": "CHEBI:63842", "name": "4C4MZYMOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_194667", "map_id": "CHEBI:50593", "name": "dh4MZYMOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10736301", "map_id": "O43050", "name": "erg26", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10736084", "map_id": "none", "name": "HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191293", "map_id": "CHEBI:57286", "name": "ACA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736081", "map_id": "P54874", "name": "hcs1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736329", "map_id": "none", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194657", "map_id": "CHEBI:63844", "name": "4CZYMOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_194661", "map_id": "CHEBI:52386", "name": "ZYMONE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10736076", "map_id": "none", "name": "FDPS dimer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191409", "map_id": "CHEBI:17211", "name": "GPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_191385", "map_id": "CHEBI:17407", "name": "FAPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736073", "map_id": "none", "name": "holo-FDPS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14230", "map_id": "O14230", "name": "fps1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6F12.13c", "map_id": "SPAC6F12.13c", "name": "fps1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745569", "map_id": "none", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_193384", "map_id": "CHEBI:16113", "name": "CHOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_171095", "map_id": "CHEBI:16113", "name": "CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10745566", "map_id": "Q9HDX5", "name": "arv1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAPB1A10.15", "map_id": "SPAPB1A10.15", "name": "arv1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736079", "map_id": "none", "name": "FDPS dimer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191324", "map_id": "CHEBI:16057", "name": "DMAPP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10736306", "map_id": "none", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_194723", "map_id": "CHEBI:63841", "name": "4MZYMOL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10736296", "map_id": "Q9UUH4", "name": "erg25", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10736102", "map_id": "none", "name": "Squalene 2,3-epoxide cyclizes, forming lanosterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191309", "map_id": "CHEBI:15441", "name": "SQOX", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736099", "map_id": "Q10231", "name": "erg7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC13G7.01c", "map_id": "SPAC13G7.01c", "name": "erg7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736134", "map_id": "none", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191265", "map_id": "CHEBI:15442", "name": "PSQPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736129", "map_id": "none", "name": "FDFT:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P36596", "map_id": "P36596", "name": "erg9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.05c", "map_id": "SPBC646.05c", "name": "erg9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736112", "map_id": "none", "name": "Mevalonate is phosphorylated to mevalonate-5-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191296", "map_id": "CHEBI:17436", "name": "MVA5P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736109", "map_id": "none", "name": "MVK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09780", "map_id": "Q09780", "name": "erg12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13G6.11c", "map_id": "SPAC13G6.11c", "name": "erg12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736122", "map_id": "none", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736119", "map_id": "none", "name": "IDI1 or 2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10132", "map_id": "Q10132", "name": "idi1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC106.15", "map_id": "SPBC106.15", "name": "idi1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736299", "map_id": "none", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736064", "map_id": "none", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_191269", "map_id": "CHEBI:15440", "name": "SQNE", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736061", "map_id": "none", "name": "SQLE:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9C1W3", "map_id": "Q9C1W3", "name": "erg1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC713.12", "map_id": "SPBC713.12", "name": "erg1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736132", "map_id": "none", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10735725", "map_id": "none", "name": "Loading of claspin onto DNA during replication origin firing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10735715", "map_id": "Q9P7T4", "name": "mrc1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC694.06c", "map_id": "SPAC694.06c", "name": "mrc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735717", "map_id": "none", "name": "Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9P7T4", "map_id": "Q9P7T4", "name": "mrc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735710", "map_id": "none", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10735705", "map_id": "none", "name": "RAD9:HUS1:RAD1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P26306", "map_id": "P26306", "name": "rad9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC664.07c", "map_id": "SPAC664.07c", "name": "rad9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78955", "map_id": "P78955", "name": "hus1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC20G4.04c", "map_id": "SPAC20G4.04c", "name": "hus1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P22193", "map_id": "P22193", "name": "rad1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1952.07", "map_id": "SPAC1952.07", "name": "rad1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735676", "map_id": "none", "name": "Rad17-RFC complex bound to DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P50531", "map_id": "P50531", "name": "rad17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC14C4.13", "map_id": "SPAC14C4.13", "name": "rad17", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10735707", "map_id": "none", "name": "Rad9-Hus1-Rad1 bound to DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10732950", "map_id": "none", "name": "Phosphorylation of Cdc25C at Ser 216 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10735678", "map_id": "none", "name": "Recruitment of Rad17-RFC complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10735674", "map_id": "none", "name": "RPA complexed to ssDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10735672", "map_id": "none", "name": "RAD17:RFC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10735686", "map_id": "none", "name": "Stalling of DNA replication fork and RPA binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_176104", "map_id": "none", "name": "Persistent single-stranded DNA", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10739846", "map_id": "none", "name": "ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_450597", "map_id": "none", "name": "mRNA Transcript Targeted by Tristetraproline", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739831", "map_id": "O14089", "name": "kap104", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC2F3.06c", "map_id": "SPAC2F3.06c", "name": "kap104", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10739842", "map_id": "P47979", "name": "zfs1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739844", "map_id": "none", "name": "TTP:mRNA Complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14089", "map_id": "O14089", "name": "kap104", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744332", "map_id": "none", "name": "Trimerization of cytosolic HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744185", "map_id": "none", "name": "Homologues of HSF1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10744288", "map_id": "none", "name": "HSF1 trimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10734704", "map_id": "none", "name": "Homologues of EEF1A1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10744290", "map_id": "none", "name": "HSF1 trimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10745134", "map_id": "none", "name": "Dissociation of HSF1:HSP90 complex in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745132", "map_id": "none", "name": "HSF1:HSP90:PTGES3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q11118", "map_id": "Q11118", "name": "wos2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC9E9.13", "map_id": "SPAC9E9.13", "name": "wos2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745124", "map_id": "Q11118", "name": "wos2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10745130", "map_id": "none", "name": "HSP90:HSP90", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10745102", "map_id": "none", "name": "Homologues of HSF1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745615", "map_id": "none", "name": "Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10745610", "map_id": "none", "name": "HSF1:HSP90:HDAC6:VCP:PTGES3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_5324631", "map_id": "none", "name": "Ub-protein aggregates", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745612", "map_id": "none", "name": "HDAC6:VCP:protein aggregates", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10744270", "map_id": "none", "name": "HSP90:HSP90", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737648", "map_id": "Q11118", "name": "wos2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10745104", "map_id": "none", "name": "Trimerization of HSF1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10744324", "map_id": "none", "name": "Dissociation of cytosolic HSF1:HSP90 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744322", "map_id": "none", "name": "HSF1:HSP90:PTGES3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10730060", "map_id": "none", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_508190", "map_id": "none", "name": "Leu, Ile, Val", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:58045", "map_id": "CHEBI:58045", "name": "CHEBI:58045", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:57427", "map_id": "CHEBI:57427", "name": "CHEBI:57427", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:57762", "map_id": "CHEBI:57762", "name": "CHEBI:57762", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_508181", "map_id": "none", "name": "KIC, KMVA, KIV", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "CHEBI:28654", "map_id": "CHEBI:28654", "name": "CHEBI:28654", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16530", "map_id": "CHEBI:16530", "name": "CHEBI:16530", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:17865", "map_id": "CHEBI:17865", "name": "CHEBI:17865", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10730057", "map_id": "none", "name": "BCAT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O14370", "map_id": "O14370", "name": "eca39", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC428.02c", "map_id": "SPBC428.02c", "name": "eca39", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730068", "map_id": "none", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_71847", "map_id": "CHEBI:28259", "name": "bHIB-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_573404", "map_id": "CHEBI:11805", "name": "bHIBA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10730065", "map_id": "O74802", "name": "ehd3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPBC2D10.09", "map_id": "SPBC2D10.09", "name": "ehd3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730052", "map_id": "none", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_508182", "map_id": "none", "name": "Leu, Ile, Val", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_508187", "map_id": "none", "name": "KIC,KMVA,KIV", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10730049", "map_id": "none", "name": "BCAT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756331", "map_id": "none", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_77343", "map_id": "CHEBI:10723", "name": "tdec2-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_77308", "map_id": "CHEBI:28493", "name": "DEC-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10756328", "map_id": "none", "name": "MECR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "Q10488", "map_id": "Q10488", "name": "etr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26F1.04c", "map_id": "SPAC26F1.04c", "name": "etr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744576", "map_id": "none", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744514", "map_id": "none", "name": "Acetylated core histone octamer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5566518", "map_id": "CHEBI:30089", "name": "acetate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744522", "map_id": "none", "name": "Core histone octamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10744573", "map_id": "P56523", "name": "clr3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10744558", "map_id": "none", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744553", "map_id": "none", "name": "Sin3A complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9Y825", "map_id": "Q9Y825", "name": "RBBP7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC25H1.06", "map_id": "SPAC25H1.06", "name": "RBBP7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14021", "map_id": "O14021", "name": "prw1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC29A4.18", "map_id": "SPAC29A4.18", "name": "prw1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59702", "map_id": "O59702", "name": "clr6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC36.05c", "map_id": "SPBC36.05c", "name": "clr6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94244", "map_id": "O94244", "name": "mis16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1672.10", "map_id": "SPCC1672.10", "name": "mis16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7M1", "map_id": "Q9P7M1", "name": "dep1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC21C3.02c", "map_id": "SPBC21C3.02c", "name": "dep1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94405", "map_id": "O94405", "name": "SAP18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC126.13c", "map_id": "SPCC126.13c", "name": "SAP18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74365", "map_id": "O74365", "name": "sol1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC30B4.04c", "map_id": "SPBC30B4.04c", "name": "sol1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744556", "map_id": "none", "name": "HDAC1:2-containing complex:HDAC2 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=7489", "map_id": "LigandDisplayForward?ligandId=7489", "name": "LigandDisplayForward?ligandId=7489", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7009", "map_id": "LigandDisplayForward?ligandId=7009", "name": "LigandDisplayForward?ligandId=7009", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7006", "map_id": "LigandDisplayForward?ligandId=7006", "name": "LigandDisplayForward?ligandId=7006", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=6852", "map_id": "LigandDisplayForward?ligandId=6852", "name": "LigandDisplayForward?ligandId=6852", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7496", "map_id": "LigandDisplayForward?ligandId=7496", "name": "LigandDisplayForward?ligandId=7496", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757824", "map_id": "none", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_9679795", "map_id": "none", "name": "HDAC2 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746196", "map_id": "none", "name": "PDPK1 phosphorylates PKN1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746165", "map_id": "none", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10746193", "map_id": "none", "name": "p-T774-PKN1,p-T816-PKN2,p-T718-PKN3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746163", "map_id": "none", "name": "RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10746159", "map_id": "none", "name": "PKN1-3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746161", "map_id": "none", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10746167", "map_id": "none", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10746791", "map_id": "none", "name": "p-T774-PKN1 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746786", "map_id": "none", "name": "p-T774-PKN1:CDC25C", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746175", "map_id": "none", "name": "Homologues of p-T774-PKN1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746788", "map_id": "none", "name": "p-T774-PKN1 binds CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10756168", "map_id": "none", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10749457", "map_id": "none", "name": "UCHL3,SENP8:NEDD8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13612", "map_id": "O13612", "name": "nep2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC32H8.02c", "map_id": "SPBC32H8.02c", "name": "nep2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10171", "map_id": "Q10171", "name": "uch1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27F1.03c", "map_id": "SPAC27F1.03c", "name": "uch1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14399", "map_id": "O14399", "name": "ubl1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749455", "map_id": "O14399", "name": "ubl1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10749446", "map_id": "none", "name": "UCHL3,SENP8", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756413", "map_id": "none", "name": "CAND1 binds cytosolic CRL E3 ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756409", "map_id": "none", "name": "CRL E3 ubiquitin ligases", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10756411", "map_id": "none", "name": "CRL E3 ubiquitin ligase:CAND1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10749462", "map_id": "none", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10749453", "map_id": "none", "name": "UCHL3,SENP8:NEDD8(1-88)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10749459", "map_id": "O14399", "name": "ubl1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10756192", "map_id": "none", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756185", "map_id": "none", "name": "NEDD8-UBA3:NAE1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UT93", "map_id": "Q9UT93", "name": "uba5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC323.06c", "map_id": "SPAC323.06c", "name": "uba5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756190", "map_id": "none", "name": "NEDD8-UBA3:NAE1:NEDD8", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756321", "map_id": "none", "name": "AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10756294", "map_id": "none", "name": "NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O43017", "map_id": "O43017", "name": "swd3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC354.03", "map_id": "SPBC354.03", "name": "swd3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74340", "map_id": "O74340", "name": "sof1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1A4.07c", "map_id": "SPBC1A4.07c", "name": "sof1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42858", "map_id": "O42858", "name": "swd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23H3.05c", "map_id": "SPAC23H3.05c", "name": "swd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94527", "map_id": "O94527", "name": "iqw1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC609.03", "map_id": "SPBC609.03", "name": "iqw1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09873", "map_id": "Q09873", "name": "wdr21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC12G12.10", "map_id": "SPAC12G12.10", "name": "wdr21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10990", "map_id": "Q10990", "name": "cdt2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17H9.19c", "map_id": "SPAC17H9.19c", "name": "cdt2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74763", "map_id": "O74763", "name": "DCAF7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17D11.08", "map_id": "SPBC17D11.08", "name": "DCAF7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q8WZK4", "map_id": "Q8WZK4", "name": "dcn1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC839.03c", "map_id": "SPBC839.03c", "name": "dcn1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756296", "map_id": "O74549", "name": "ubc12", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10756318", "map_id": "none", "name": "NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756214", "map_id": "none", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756195", "map_id": "O74549", "name": "ubc12", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10756197", "map_id": "none", "name": "AcM-UBE2M:NEDD8-UBA3:NAE1:NEDD8", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756208", "map_id": "none", "name": "Transfer of NEDD8 to AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756205", "map_id": "none", "name": "NEDD8-AcM-UBE2M", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756250", "map_id": "none", "name": "AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756235", "map_id": "none", "name": "NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10756247", "map_id": "none", "name": "NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756419", "map_id": "none", "name": "CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10756415", "map_id": "Q9P3A8", "name": "knd1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10756280", "map_id": "none", "name": "RBX1:CUL4:DDB1:DCAFs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10756417", "map_id": "none", "name": "CRL4 E3 ubiquitin ligase:CAND1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756188", "map_id": "none", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756175", "map_id": "none", "name": "UBA3:NAE1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10754241", "map_id": "none", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10754239", "map_id": "none", "name": "Homologues of UBA52(1-128)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729083", "map_id": "none", "name": "Homologues of RPS27A(1-76)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10732101", "map_id": "none", "name": "Homologues of RPL40", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10754226", "map_id": "none", "name": "UCHL3,USP7,USP9X", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10754194", "map_id": "none", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741355", "map_id": "O94609", "name": "ptr3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10754094", "map_id": "none", "name": "UBA1:ubiquitin adenylate", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10754183", "map_id": "none", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10754148", "map_id": "none", "name": "Ub-Cys632-UBA1:ubiquitin adenylate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10754162", "map_id": "none", "name": "E2 ubiquitin conjugating enzyme (UBA1 substrate)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10754181", "map_id": "none", "name": "Ub:E2 (UBA1 substrate)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10753992", "map_id": "none", "name": "UBA1:ubiquitin adenylate", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10753994", "map_id": "none", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10753862", "map_id": "O94609", "name": "ptr3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10754144", "map_id": "none", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10753996", "map_id": "none", "name": "E2 ubiquitin conjugating enzyme (UBA1 substrate)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10754092", "map_id": "none", "name": "Ub-Cys632-UBA1:ubiquitin adenylate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10754142", "map_id": "none", "name": "Ub:E2 (UBA1 substrate)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10754254", "map_id": "none", "name": "OTULIN,USP5 cleaves UBC yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10754251", "map_id": "none", "name": "Homologues of UBC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729113", "map_id": "none", "name": "Homologues of UBC(229-304)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729093", "map_id": "none", "name": "Homologues of UBB(77-152)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729103", "map_id": "none", "name": "Homologues of UBB(153-228)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729163", "map_id": "none", "name": "Homologues of UBC(609-684)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729153", "map_id": "none", "name": "Homologues of UBC(533-608)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729143", "map_id": "none", "name": "Homologues of UBC(457-532)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729133", "map_id": "none", "name": "Homologues of UBC(381-456)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10729123", "map_id": "none", "name": "Homologues of UBC(305-380)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10748788", "map_id": "Q11119", "name": "ubp14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10754191", "map_id": "none", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10753998", "map_id": "none", "name": "Ub-Cys632-UBA1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10754188", "map_id": "none", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10754196", "map_id": "none", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10754146", "map_id": "none", "name": "Ub-Cys632-UBA1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10754185", "map_id": "none", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10754266", "map_id": "none", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10754264", "map_id": "none", "name": "Homologues of UBB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10754229", "map_id": "none", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731576", "map_id": "none", "name": "Homologues of RPS27A(77-156)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10732286", "map_id": "none", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111647", "map_id": "CHEBI:58228", "name": "CAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732277", "map_id": "none", "name": "CAD hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94313", "map_id": "O94313", "name": "arg4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC215.08c", "map_id": "SPBC215.08c", "name": "arg4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09794", "map_id": "Q09794", "name": "ura1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22G7.06c", "map_id": "SPAC22G7.06c", "name": "ura1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732266", "map_id": "none", "name": "DHODH:FMN oxidises (S)-DHO to orotate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76630", "map_id": "CHEBI:30864", "name": "(S)-DHO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_76632", "map_id": "CHEBI:30839", "name": "ORO", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732263", "map_id": "none", "name": "DHODH:FMN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "P32747", "map_id": "P32747", "name": "ura3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC57A10.12c", "map_id": "SPAC57A10.12c", "name": "ura3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732280", "map_id": "none", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111628", "map_id": "CHEBI:32814", "name": "N-carb-L-Asp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10732283", "map_id": "none", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10746504", "map_id": "none", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746500", "map_id": "none", "name": "ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746496", "map_id": "none", "name": "Homologues of USP43", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746502", "map_id": "none", "name": "USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746510", "map_id": "none", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746506", "map_id": "none", "name": "PCNA:RPA:RFC:TLS-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10734037", "map_id": "none", "name": "POLD,POLE", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746508", "map_id": "none", "name": "PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733936", "map_id": "none", "name": "Cleavage of ethenocytosine by TDG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733933", "map_id": "none", "name": "TDG:EtCYT-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110233", "map_id": "CHEBI:29147", "name": "EtCYT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10734052", "map_id": "none", "name": "POLD,POLE-mediated DNA strand displacement synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734049", "map_id": "none", "name": "APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10734045", "map_id": "none", "name": "APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733885", "map_id": "none", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733882", "map_id": "none", "name": "UNG-1:5-OHU-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O74834", "map_id": "O74834", "name": "ung1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1183.06", "map_id": "SPCC1183.06", "name": "ung1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733875", "map_id": "none", "name": "UNG-1:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110216", "map_id": "CHEBI:29115", "name": "5-OHU", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10733892", "map_id": "none", "name": "Cleavage of uracil by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733887", "map_id": "none", "name": "TDG:(Ura:Gua)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_29554", "map_id": "CHEBI:17568", "name": "Ura", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10733899", "map_id": "none", "name": "Cleavage of thymine by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733896", "map_id": "none", "name": "TDG:(T:G)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_29692", "map_id": "CHEBI:17821", "name": "Thy", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10746388", "map_id": "none", "name": "LIG1 bound to APEX1 and PCNA ligates SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734058", "map_id": "none", "name": "LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P12000", "map_id": "P12000", "name": "cdc17", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746385", "map_id": "none", "name": "LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733929", "map_id": "none", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733926", "map_id": "none", "name": "NTHL1:FapyA-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q09907", "map_id": "Q09907", "name": "nth1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC30D11.07", "map_id": "SPAC30D11.07", "name": "nth1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5637659", "map_id": "CHEBI:27983", "name": "FapyA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10733905", "map_id": "none", "name": "NTHL1:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733908", "map_id": "none", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733903", "map_id": "none", "name": "NTHL1:Tg-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110223", "map_id": "CHEBI:29128", "name": "Tg", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10733915", "map_id": "none", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733912", "map_id": "none", "name": "NTHL1:Cg-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110225", "map_id": "CHEBI:29127", "name": "Cg", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10733952", "map_id": "none", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733947", "map_id": "none", "name": "MUTYH:(8oxoG:Ade)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q10159", "map_id": "Q10159", "name": "myh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26A3.02", "map_id": "SPAC26A3.02", "name": "myh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733949", "map_id": "none", "name": "MUTYH:AP-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_5635947", "map_id": "CHEBI:16708", "name": "Ade", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10733878", "map_id": "none", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733871", "map_id": "none", "name": "UNG-1:(Ura:Gua)-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733922", "map_id": "none", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733919", "map_id": "none", "name": "NTHL1:DHU-dsDNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_30140", "map_id": "CHEBI:15901", "name": "DHU", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10734060", "map_id": "none", "name": "LIG1 binds APEX1 and PCNA at SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734056", "map_id": "none", "name": "APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10735879", "map_id": "none", "name": "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_189108", "map_id": "CHEBI:28912", "name": "limit dextrins", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_191103", "map_id": "CHEBI:27931", "name": "maltotriose", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_188986", "map_id": "CHEBI:17306", "name": "Mal", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10735876", "map_id": "none", "name": "sucrase-isomaltase dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10736054", "map_id": "none", "name": "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10735886", "map_id": "none", "name": "MGAM dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10736052", "map_id": "none", "name": "maltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10735882", "map_id": "none", "name": "sucrose + H2O => glucose + fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_188980", "map_id": "CHEBI:17992", "name": "Suc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_189049", "map_id": "CHEBI:15824", "name": "Fru", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10735889", "map_id": "none", "name": "maltose + H2O => 2 D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10746655", "map_id": "none", "name": "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_5659875", "map_id": "CHEBI:28189", "name": "iMal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10736050", "map_id": "none", "name": "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10728699", "map_id": "none", "name": "Formation of ORC(1-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728693", "map_id": "none", "name": "ORC1:origin of replication", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10728682", "map_id": "none", "name": "ORC(2-5)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10728697", "map_id": "none", "name": "ORC(1-5):origin of replication", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10758124", "map_id": "none", "name": "MCM2 binds MCM4:MCM6:MCM7 heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728847", "map_id": "none", "name": "MCM2:MCM4:MCM6:MCM7", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10758076", "map_id": "none", "name": "ORC1 binds to H4K20me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728689", "map_id": "P54789", "name": "orc1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10758072", "map_id": "none", "name": "H4K20Me2-nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10758074", "map_id": "none", "name": "ORC1:H4K20Me2-nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10758120", "map_id": "none", "name": "MCM3 binds MCM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728859", "map_id": "none", "name": "MCM3:MCM5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10728666", "map_id": "none", "name": "ORC2 binds ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728657", "map_id": "Q09142", "name": "orc2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728662", "map_id": "Q10067", "name": "orc3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728664", "map_id": "none", "name": "ORC2:ORC3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10758078", "map_id": "none", "name": "Formation of MCM2-7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10758051", "map_id": "none", "name": "ORC6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10758033", "map_id": "none", "name": "p-T195-ORC6:KPNA1,KPNA6:KPNB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14063", "map_id": "O14063", "name": "cut15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC962.03c", "map_id": "SPCC962.03c", "name": "cut15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94374", "map_id": "O94374", "name": "imp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1604.08c", "map_id": "SPBC1604.08c", "name": "imp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10728705", "map_id": "O74796", "name": "phospho-orc6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10758049", "map_id": "none", "name": "KPNA1,KPNA6:KPNB1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10758122", "map_id": "none", "name": "MCM4, MCM6 and MCM7 form a heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728843", "map_id": "O75001", "name": "mcm7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728838", "map_id": "P49731", "name": "mcm6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728833", "map_id": "P29458", "name": "mcm4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10758029", "map_id": "none", "name": "ORC6 binds KPNA1 or KPNA6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10758023", "map_id": "none", "name": "KPNA1,KPNA6:KPNB1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10758025", "map_id": "O74796", "name": "orc6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10758027", "map_id": "none", "name": "ORC6:KPNA1,KPNA6:KPNB1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10758055", "map_id": "none", "name": "ORC1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10758053", "map_id": "P54789", "name": "orc1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10728675", "map_id": "none", "name": "ORC5 binds ORC2:ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728671", "map_id": "O43114", "name": "orc5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10728673", "map_id": "none", "name": "ORC2:ORC3:ORC5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10728684", "map_id": "none", "name": "Formation of ORC(2-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728680", "map_id": "Q9Y794", "name": "orc4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10728718", "map_id": "none", "name": "CDC6 association with ORC(1-6) at replication origins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10728707", "map_id": "none", "name": "ORC(1-6):origin of replication", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10728716", "map_id": "none", "name": "ORC(1-6):CDC6:origin of replication", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10758035", "map_id": "none", "name": "ORC6 is phosphorylated on T195", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10728709", "map_id": "none", "name": "Formation of ORC(1-6) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10747495", "map_id": "none", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747490", "map_id": "none", "name": "p-T68-CHEK2 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q10292", "map_id": "Q10292", "name": "phospho-mek1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10747492", "map_id": "none", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747488", "map_id": "Q10292", "name": "phospho-mek1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10734987", "map_id": "none", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733361", "map_id": "Q9US20", "name": "AGPAT1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10734985", "map_id": "none", "name": "Transcriptional activation of Acetyl-CoA carboxylase by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734983", "map_id": "P78820", "name": "cut6", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10734565", "map_id": "none", "name": "Phosphorylation of Syntaxin-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734560", "map_id": "Q9USH7", "name": "psy1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734563", "map_id": "Q9USH7", "name": "phospho-psy1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734542", "map_id": "none", "name": "Activated conventional protein kinase C", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10734555", "map_id": "none", "name": "Phosphorylation of Platelet Sec-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734549", "map_id": "O94590", "name": "sec1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC584.05", "map_id": "SPCC584.05", "name": "phospho-sec1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734552", "map_id": "O94590", "name": "phospho-sec1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10735552", "map_id": "none", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_174370", "map_id": "CHEBI:17709", "name": "APS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_158471", "map_id": "CHEBI:58339", "name": "PAPS", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735547", "map_id": "Q9P7G9", "name": "met14", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC1782.11", "map_id": "SPAC1782.11", "name": "met14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735571", "map_id": "none", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10743381", "map_id": "none", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10743369", "map_id": "none", "name": "CK2 Phosphorylated Condensin I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P41003", "map_id": "P41003", "name": "cut14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP4H10.06c", "map_id": "SPBP4H10.06c", "name": "cut14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P41004", "map_id": "P41004", "name": "cut3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC146.03c", "map_id": "SPBC146.03c", "name": "cut3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7R3", "map_id": "Q9Y7R3", "name": "cnd2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC306.03c", "map_id": "SPCC306.03c", "name": "cnd2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10429", "map_id": "Q10429", "name": "cnd3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC188.03", "map_id": "SPCC188.03", "name": "cnd3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94679", "map_id": "O94679", "name": "cnd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC776.13", "map_id": "SPBC776.13", "name": "cnd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743379", "map_id": "none", "name": "Condensin I", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_2529006", "map_id": "none", "name": "Unknown Phosphatase", "type": "catalyst", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10743406", "map_id": "none", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10733244", "map_id": "none", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733240", "map_id": "Q09683", "name": "rad32", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10733235", "map_id": "Q9UTJ8", "name": "rad50", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10733242", "map_id": "none", "name": "RAD50:MRE11A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749600", "map_id": "none", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747252", "map_id": "none", "name": "DNA DSBs:MRN:Ac-K3016-ATM dimer:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10737781", "map_id": "O74630", "name": "phospho-tel1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10749597", "map_id": "none", "name": "DNA DSBs:MRN:p-S1981,Ac-K3016-ATM:KAT5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747255", "map_id": "none", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747250", "map_id": "none", "name": "DNA DSBs:MRN:ATM dimer:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_113560", "map_id": "CHEBI:57288", "name": "Ac-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_2485002", "map_id": "CHEBI:57287", "name": "CoA-SH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10747567", "map_id": "none", "name": "KPNA2 translocates NBN to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747559", "map_id": "none", "name": "NBN:KPNA2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10747565", "map_id": "none", "name": "Homologues of KPNA2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733249", "map_id": "O43070", "name": "nbs1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10733253", "map_id": "none", "name": "Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733251", "map_id": "none", "name": "MRN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747569", "map_id": "none", "name": "NBN binds KPNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747555", "map_id": "none", "name": "Homologues of KPNA2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10747557", "map_id": "O43070", "name": "nbs1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10744580", "map_id": "none", "name": "MRN complex binds DNA double strand breaks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_75165", "map_id": "none", "name": "DNA double-strand break ends", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744578", "map_id": "none", "name": "DNA DSBs:MRN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749630", "map_id": "none", "name": "MRN complex bound to DNA ends recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747231", "map_id": "none", "name": "ATM dimer:KAT5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10730078", "map_id": "none", "name": "lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_29444", "map_id": "CHEBI:32551", "name": "L-Lys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_30176", "map_id": "CHEBI:16927", "name": "SACN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10730075", "map_id": "none", "name": "AASS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O59711", "map_id": "O59711", "name": "lys9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B8.03", "map_id": "SPBC3B8.03", "name": "lys9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730211", "map_id": "none", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_70951", "map_id": "CHEBI:15753", "name": "aKADA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_70955", "map_id": "CHEBI:15524", "name": "GL-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10730081", "map_id": "none", "name": "saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10750324", "map_id": "none", "name": "PIPOX oxidises PPCA to P6C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix" }, { "id": "species_5693325", "map_id": "CHEBI:30913", "name": "PPCA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_6783877", "map_id": "CHEBI:58769", "name": "P6C", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "species_10750321", "map_id": "O43029", "name": "fap1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17951", "compartment_display": "peroxisomal matrix", "complex": "false" }, { "id": "reaction_10753848", "map_id": "none", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8851462", "map_id": "none", "name": "CDP,GDP,IDP,UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:58280", "map_id": "CHEBI:58280", "name": "CHEBI:58280", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_8851461", "map_id": "none", "name": "CMP,GMP,IMP,UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10753845", "map_id": "none", "name": "NTPDase6:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q9USP2", "map_id": "Q9USP2", "name": "ynd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC11E10.05c", "map_id": "SPCC11E10.05c", "name": "ynd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753831", "map_id": "none", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_8851224", "map_id": "none", "name": "UDP,GDP,CDP,dTDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_2022884", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_8851227", "map_id": "none", "name": "UMP,GMP,CMP,dTMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "species_8851226", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "false" }, { "id": "species_10753828", "map_id": "none", "name": "NTPDase4:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10753786", "map_id": "none", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_8870906", "map_id": "CHEBI:57930", "name": "NDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8870962", "map_id": "CHEBI:58043", "name": "NMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10753780", "map_id": "none", "name": "NTPDase1:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10753824", "map_id": "none", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_10753818", "map_id": "none", "name": "NTPDase3:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10753834", "map_id": "none", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17963", "compartment_display": "Golgi lumen" }, { "id": "species_8851233", "map_id": "none", "name": "UTP,GTP,CTP,dTTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17963", "compartment_display": "Golgi lumen", "complex": "true" }, { "id": "reaction_10753821", "map_id": "none", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8870907", "map_id": "CHEBI:61557", "name": "NTP", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "reaction_10753855", "map_id": "none", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen" }, { "id": "species_8851509", "map_id": "none", "name": "CTP,GTP,UTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "true" }, { "id": "species_8851517", "map_id": "CHEBI:15377", "name": "H2O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "false" }, { "id": "species_8851518", "map_id": "none", "name": "CDP,GDP,UDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "true" }, { "id": "species_8851513", "map_id": "CHEBI:43474", "name": "Pi", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "false" }, { "id": "species_5228597", "map_id": "CHEBI:15378", "name": "H+", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_528865", "compartment_display": "endocytic vesicle lumen", "complex": "false" }, { "id": "species_10753852", "map_id": "none", "name": "NTPDase7:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_24337", "compartment_display": "endocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10753783", "map_id": "none", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10753857", "map_id": "none", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9726184", "map_id": "none", "name": "ATP,GTP,ITP,CTP,TTP,UTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_2509836", "map_id": "CHEBI:61402", "name": "ITP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9726189", "map_id": "none", "name": "ADP,GDP,IDP,CDP,TDP,UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10753811", "map_id": "none", "name": "NTPDase2:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10753841", "map_id": "none", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8936165", "map_id": "none", "name": "ADP,GDP,CDP,UDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_8851369", "map_id": "none", "name": "AMP,GMP,CMP,UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_10753838", "map_id": "none", "name": "NPTDase5:Ca2+,Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10753814", "map_id": "none", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8936166", "map_id": "none", "name": "ATP,GTP,CTP,ITP,UTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "species_8851092", "map_id": "none", "name": "ADP,GDP,CDP,IDP,UDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10753860", "map_id": "none", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_9726186", "map_id": "none", "name": "AMP,GMP,IMP,CMP,TMP,UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10746363", "map_id": "none", "name": "RAB11A:GTP-containing Golgi vesicles recruit RAB3IP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13949", "compartment_display": "Golgi-associated vesicle membrane" }, { "id": "species_10746359", "map_id": "none", "name": "Homologues of RAB3IP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746347", "map_id": "none", "name": "RAB11A:GTP:Golgi derived vesicle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13949", "compartment_display": "Golgi-associated vesicle membrane", "complex": "true" }, { "id": "species_10746361", "map_id": "none", "name": "RAB3IP:RAB11A:GTP:Golgi-derived vesicle", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13949", "compartment_display": "Golgi-associated vesicle membrane", "complex": "true" }, { "id": "reaction_10756951", "map_id": "none", "name": "RHOT1 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756946", "map_id": "none", "name": "RHOT1:GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "O59781", "map_id": "O59781", "name": "gem1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC320.04c", "map_id": "SPCC320.04c", "name": "gem1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756948", "map_id": "none", "name": "RHOT1:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10756961", "map_id": "none", "name": "RHOT1 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10756957", "map_id": "none", "name": "Homologues of MYO19", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "O74805", "map_id": "O74805", "name": "myo51", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2D10.14c", "map_id": "SPBC2D10.14c", "name": "myo51", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94477", "map_id": "O94477", "name": "myo52", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1919.10c", "map_id": "SPCC1919.10c", "name": "myo52", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756959", "map_id": "none", "name": "RHOT1:GTP:RHOT1 effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10746671", "map_id": "none", "name": "SORD tetramer oxidizes xylitol to D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5660033", "map_id": "CHEBI:17151", "name": "xylitol", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5661281", "map_id": "CHEBI:17140", "name": "D-xylulose", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10746446", "map_id": "none", "name": "SORD tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P36624", "map_id": "P36624", "name": "tms1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1773.05c", "map_id": "SPBC1773.05c", "name": "tms1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746668", "map_id": "none", "name": "XYLB phosphorylates D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746665", "map_id": "Q9C0U6", "name": "xks1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCPJ732.02c", "map_id": "SPCPJ732.02c", "name": "xks1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746139", "map_id": "none", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746135", "map_id": "none", "name": "ARF4:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10745780", "map_id": "none", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358527", "map_id": "none", "name": "DNA containing IDL of 2 or more bases", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10745776", "map_id": "none", "name": "MSH2:MSH3:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P26359", "map_id": "P26359", "name": "msh3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC8F11.03", "map_id": "SPAC8F11.03", "name": "msh3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74773", "map_id": "O74773", "name": "msh2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19G7.01c", "map_id": "SPBC19G7.01c", "name": "msh2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745778", "map_id": "none", "name": "MSH2:MSH3:ADP:DNA containing IDL of 2 bases or more", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750285", "map_id": "none", "name": "Ligation of newly synthesized repair patch to incised DNA in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10750271", "map_id": "none", "name": "TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10749293", "map_id": "none", "name": "(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10750283", "map_id": "none", "name": "TC-NER post-incision complex:dsDNA with transcription bubble", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746607", "map_id": "none", "name": "POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746599", "map_id": "none", "name": "POLK:Mg2+,Mn2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746603", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733995", "map_id": "none", "name": "POLZ", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q0E7J8", "map_id": "Q0E7J8", "name": "rev7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC12D12.09", "map_id": "SPBC12D12.09", "name": "rev7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P6L6", "map_id": "Q9P6L6", "name": "rev3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC688.10", "map_id": "SPAC688.10", "name": "rev3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733957", "map_id": "O94623", "name": "rev1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC1347.01c", "map_id": "SPBC1347.01c", "name": "rev1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746605", "map_id": "none", "name": "POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O94623", "map_id": "O94623", "name": "rev1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746433", "map_id": "none", "name": "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746426", "map_id": "none", "name": "RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746430", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746424", "map_id": "none", "name": "RAD18:UBE2B,RBX1:CUL4:DDB1:DTL", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745785", "map_id": "none", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745767", "map_id": "none", "name": "MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P54280", "map_id": "P54280", "name": "pms1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC19G12.02c", "map_id": "SPAC19G12.02c", "name": "pms1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74502", "map_id": "O74502", "name": "msh6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC285.16c", "map_id": "SPCC285.16c", "name": "msh6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7W6", "map_id": "Q9P7W6", "name": "mlh1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1703.04", "map_id": "SPBC1703.04", "name": "mlh1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745782", "map_id": "none", "name": "MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749595", "map_id": "none", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10749592", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:MDC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10747437", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745797", "map_id": "none", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358610", "map_id": "none", "name": "DNA containing single strand nick (5' phosphate, 3' hydroxyl)", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_109966", "map_id": "none", "name": "Repaired double-stranded DNA", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10747479", "map_id": "none", "name": "PPP5C dephosphorylates TP53BP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747469", "map_id": "none", "name": "DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O94451", "map_id": "O94451", "name": "pli1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14026", "map_id": "O14026", "name": "set2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC29B12.02c", "map_id": "SPAC29B12.02c", "name": "set2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87074", "map_id": "P87074", "name": "crb2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC342.05", "map_id": "SPBC342.05", "name": "crb2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747471", "map_id": "none", "name": "DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10747476", "map_id": "O43049", "name": "ppt1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC3F6.01c", "map_id": "SPBC3F6.01c", "name": "ppt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750503", "map_id": "none", "name": "SUMOylation of XPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10749477", "map_id": "none", "name": "Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O74803", "map_id": "O74803", "name": "rhp23", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2D10.12", "map_id": "SPBC2D10.12", "name": "rhp23", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750487", "map_id": "none", "name": "SUMO1,2,3:UBE2I", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10750496", "map_id": "none", "name": "Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10750500", "map_id": "none", "name": "PIAS1,3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733974", "map_id": "none", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733970", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733972", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746644", "map_id": "none", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746635", "map_id": "none", "name": "POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746641", "map_id": "none", "name": "POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749297", "map_id": "none", "name": "DNA polymerases delta, epsilon or kappa bind the GG-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10749281", "map_id": "none", "name": "GG-NER incision complex:5'-incised damaged DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10749295", "map_id": "none", "name": "GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745941", "map_id": "none", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745744", "map_id": "Q9P7W6", "name": "mlh1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10745749", "map_id": "P54280", "name": "pms1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10745751", "map_id": "none", "name": "MLH1:PMS2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747451", "map_id": "none", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747446", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10747439", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:p-S102-WHSC1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747379", "map_id": "none", "name": "HERC2 facilitates UBE2N:UBE2V2 binding to RNF8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747364", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10747377", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745795", "map_id": "none", "name": "DNA polymerase delta polymerizes DNA across single stranded gap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745793", "map_id": "none", "name": "RPA:DNA containing single strand gap", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749612", "map_id": "none", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747312", "map_id": "none", "name": "DNA DSB:p-MRN:p-S1981,Ac-K3016-ATM:KAT5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745791", "map_id": "none", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_5358514", "map_id": "none", "name": "DNA containing mismatch or 1-2 base IDL", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10745787", "map_id": "none", "name": "MSH2:MSH6:ADP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10745789", "map_id": "none", "name": "MSH2:MSH6:ADP:DNA containing 1-2 base mismatch", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746625", "map_id": "none", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746613", "map_id": "none", "name": "POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746622", "map_id": "none", "name": "POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746590", "map_id": "none", "name": "USP1:WDR48 binds monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746581", "map_id": "none", "name": "USP1:WDR48", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q09731", "map_id": "Q09731", "name": "bun107", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC31A2.14", "map_id": "SPAC31A2.14", "name": "bun107", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7V9", "map_id": "Q9P7V9", "name": "ubp9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1703.12", "map_id": "SPBC1703.12", "name": "ubp9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746583", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749487", "map_id": "none", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10749464", "map_id": "none", "name": "(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10749484", "map_id": "none", "name": "(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750274", "map_id": "none", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10745769", "map_id": "none", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745765", "map_id": "none", "name": "MSH2:MSH6:ATP:DNA containing 1-2 base mismatch", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745937", "map_id": "none", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745756", "map_id": "O74773", "name": "msh2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10745774", "map_id": "P26359", "name": "msh3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10749480", "map_id": "none", "name": "ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10749473", "map_id": "none", "name": "Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747448", "map_id": "none", "name": "WHSC1 binds DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747441", "map_id": "O14026", "name": "set2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10749607", "map_id": "none", "name": "TP53BP1 associates with H4K20Me2 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743694", "map_id": "P87074", "name": "crb2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10747455", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746597", "map_id": "none", "name": "USP1 autocleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746592", "map_id": "Q9P7V9", "name": "ubp9", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10746579", "map_id": "Q09731", "name": "bun107", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10746594", "map_id": "Q9P7V9", "name": "ubp9", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10734004", "map_id": "none", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733997", "map_id": "none", "name": "POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10734001", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749469", "map_id": "none", "name": "5'- incision of DNA by ERCC1:ERCC4 in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10749466", "map_id": "none", "name": "GG-NER incision complex:Open bubble dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747367", "map_id": "none", "name": "PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747350", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:p-T4827-HERC2:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747463", "map_id": "none", "name": "RNF8 and RNF168 ubiquitinate KDM4A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747420", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10747458", "map_id": "O94691", "name": "jmj3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10747353", "map_id": "none", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747346", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:HERC2:PIAS4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747444", "map_id": "none", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747334", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746428", "map_id": "none", "name": "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746392", "map_id": "none", "name": "PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747820", "map_id": "none", "name": "Recruitment of XPA and release of CAK ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747816", "map_id": "none", "name": "Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10747818", "map_id": "none", "name": "Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749628", "map_id": "none", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747536", "map_id": "none", "name": "p-Y142-H2AFX-Nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10749602", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745811", "map_id": "none", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10734026", "map_id": "none", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734015", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O42917", "map_id": "O42917", "name": "eso1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16A3.11", "map_id": "SPBC16A3.11", "name": "eso1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734023", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745939", "map_id": "none", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745761", "map_id": "O74502", "name": "msh6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10747482", "map_id": "none", "name": "ATM phosphorylates TP53BP1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10745806", "map_id": "none", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745802", "map_id": "P53695", "name": "exo1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC29A10.05", "map_id": "SPBC29A10.05", "name": "exo1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745804", "map_id": "none", "name": "EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P53695", "map_id": "P53695", "name": "exo1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10733831", "map_id": "none", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733822", "map_id": "Q06182", "name": "swi10", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10733827", "map_id": "P36617", "name": "rad16", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10734035", "map_id": "none", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733993", "map_id": "Q0E7J8", "name": "rev7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10733988", "map_id": "Q9P6L6", "name": "rev3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10745809", "map_id": "none", "name": "EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10746435", "map_id": "none", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733980", "map_id": "none", "name": "REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746653", "map_id": "none", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746650", "map_id": "none", "name": "POLI:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734017", "map_id": "none", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734013", "map_id": "none", "name": "MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10734009", "map_id": "O42917", "name": "eso1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10746588", "map_id": "none", "name": "USP1:WDR48 deubiquitinates monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746585", "map_id": "none", "name": "PCNA:RPA:RFC:Damaged DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746564", "map_id": "none", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746544", "map_id": "none", "name": "SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10746560", "map_id": "none", "name": "NPLOC4:UFD1L:VCP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O42915", "map_id": "O42915", "name": "ufd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16A3.09c", "map_id": "SPBC16A3.09c", "name": "ufd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P780", "map_id": "Q9P780", "name": "npl4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1711.10c", "map_id": "SPBC1711.10c", "name": "npl4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746562", "map_id": "none", "name": "NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733983", "map_id": "none", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10749609", "map_id": "none", "name": "MDC1 associates with gamma-H2AFX at nuclear foci", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747435", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10749590", "map_id": "none", "name": "MDC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749471", "map_id": "none", "name": "Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747788", "map_id": "none", "name": "GG-NER pre-incision complex:Open bubble-dsDNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747423", "map_id": "none", "name": "RNF8 and RNF168 ubiquitinate H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747398", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746616", "map_id": "none", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10749977", "map_id": "none", "name": "USP45 deubiquitinates ERCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10749972", "map_id": "none", "name": "Ub:ERCC1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10749974", "map_id": "Q9P7S5", "name": "ubp7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC23G3.08c", "map_id": "SPAC23G3.08c", "name": "ubp7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734033", "map_id": "none", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734030", "map_id": "none", "name": "POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746569", "map_id": "none", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746566", "map_id": "none", "name": "NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747453", "map_id": "none", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747336", "map_id": "O94691", "name": "jmj3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10747340", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:KDM4A,B:p-S102-WHSC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747790", "map_id": "none", "name": "Formation of the pre-incision complex in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747786", "map_id": "none", "name": "Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749605", "map_id": "none", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747546", "map_id": "none", "name": "DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10743005", "map_id": "none", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162256", "map_id": "CHEBI:16584", "name": "IPPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162257", "map_id": "CHEBI:17407", "name": "FPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162214", "map_id": "CHEBI:61011", "name": "all-E-10PrP2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10743002", "map_id": "none", "name": "PDSS1/2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O13851", "map_id": "O13851", "name": "dlp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC19G12.12", "map_id": "SPAC19G12.12", "name": "dlp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O43091", "map_id": "O43091", "name": "dps1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBPJ4664.01", "map_id": "SPBPJ4664.01", "name": "dps1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742984", "map_id": "none", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162209", "map_id": "CHEBI:50775", "name": "DHDB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162215", "map_id": "CHEBI:50776", "name": "MHDB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10742970", "map_id": "O74421", "name": "coq3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPCC162.05", "map_id": "SPCC162.05", "name": "coq3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742973", "map_id": "none", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2162212", "map_id": "CHEBI:64182", "name": "DeMQ10H2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162198", "map_id": "CHEBI:64183", "name": "Q10H2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10742981", "map_id": "none", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_2162213", "map_id": "CHEBI:30763", "name": "PHB", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_2162207", "map_id": "CHEBI:64136", "name": "DHB", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10742978", "map_id": "Q10252", "name": "ppt1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10734456", "map_id": "none", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734280", "map_id": "none", "name": "CCNT1,CCNT2,CCNK", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O74627", "map_id": "O74627", "name": "pch1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC32F12.06", "map_id": "SPBC32F12.06", "name": "pch1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59748", "map_id": "O59748", "name": "lsc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC530.13", "map_id": "SPBC530.13", "name": "lsc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734258", "map_id": "O14098", "name": "lsk1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10734282", "map_id": "none", "name": "P-TEFb complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734442", "map_id": "none", "name": "Resumption of elongation after recovery from pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734440", "map_id": "none", "name": "Paused processive elongation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q09915", "map_id": "Q09915", "name": "spt6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1F7.01c", "map_id": "SPAC1F7.01c", "name": "spt6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10319", "map_id": "Q10319", "name": "yaf9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17G8.07", "map_id": "SPAC17G8.07", "name": "yaf9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P376", "map_id": "Q9P376", "name": "fcp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC19B12.05c", "map_id": "SPAC19B12.05c", "name": "fcp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94267", "map_id": "O94267", "name": "spt16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP8B7.19", "map_id": "SPBP8B7.19", "name": "spt16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "A0ZWU1", "map_id": "A0ZWU1", "name": "eaf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1223.10c", "map_id": "SPCC1223.10c", "name": "eaf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42668", "map_id": "O42668", "name": "tpr1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27D7.14c", "map_id": "SPAC27D7.14c", "name": "tpr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUE7", "map_id": "Q9UUE7", "name": "cdc73", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17G9.02c", "map_id": "SPBC17G9.02c", "name": "cdc73", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7K8", "map_id": "Q9P7K8", "name": "spt4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC21C3.16c", "map_id": "SPBC21C3.16c", "name": "spt4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13936", "map_id": "O13936", "name": "phospho-spt5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23C4.19", "map_id": "SPAC23C4.19", "name": "phospho-spt5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94529", "map_id": "O94529", "name": "pob3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC609.05", "map_id": "SPBC609.05", "name": "pob3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42964", "map_id": "O42964", "name": "iws1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19G7.16", "map_id": "SPBC19G7.16", "name": "iws1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59671", "map_id": "O59671", "name": "pof4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29A3.08", "map_id": "SPBC29A3.08", "name": "pof4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94667", "map_id": "O94667", "name": "RTF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC651.09c", "map_id": "SPBC651.09c", "name": "RTF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P6R2", "map_id": "Q9P6R2", "name": "LEO1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC13E7.08c", "map_id": "SPBC13E7.08c", "name": "LEO1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94436", "map_id": "O94436", "name": "tfg3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22H12.02", "map_id": "SPAC22H12.02", "name": "tfg3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9US06", "map_id": "Q9US06", "name": "PAF1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC664.03", "map_id": "SPAC664.03", "name": "PAF1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734436", "map_id": "none", "name": "Processive elongation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734458", "map_id": "none", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733600", "map_id": "O13936", "name": "phospho-spt5", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10734297", "map_id": "Q9P7K8", "name": "spt4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10734299", "map_id": "none", "name": "DSIF complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733342", "map_id": "none", "name": "Fall Back to Closed Pre-initiation Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733332", "map_id": "none", "name": "pol II open pre-initiation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734468", "map_id": "none", "name": "TFIIS-mediated recovery of elongation from arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10734454", "map_id": "none", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734357", "map_id": "O94267", "name": "spt16", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10734352", "map_id": "O94529", "name": "pob3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10734359", "map_id": "none", "name": "FACT complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734462", "map_id": "none", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734367", "map_id": "none", "name": "DSIF:NELF:early elongation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10732715", "map_id": "none", "name": "Abortive initiation after formation of the first phosphodiester bond", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10732713", "map_id": "none", "name": "pol II transcription complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_109877", "map_id": "none", "name": "template DNA with first transcript dinucleotide, opened to +8 position", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10733330", "map_id": "none", "name": "Abortive Initiation Before Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733328", "map_id": "none", "name": "Pol II Promoter Escape Complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_110068", "map_id": "none", "name": "DNA containing Pol II promoter with transcript with 2 or 3 nucleotides", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10734446", "map_id": "none", "name": "Abortive termination of elongation after arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734444", "map_id": "none", "name": "Aborted elongation complex after arrest", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734464", "map_id": "none", "name": "2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10734470", "map_id": "none", "name": "7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10733400", "map_id": "none", "name": "Abortive Initiation After Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733398", "map_id": "none", "name": "pol II transcription complex containing 4-9 nucleotide long transcript", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_75897", "map_id": "none", "name": "template DNA:4-9 nucleotide transcript hybrid", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10737527", "map_id": "none", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_209793", "map_id": "CHEBI:17697", "name": "Ac5HT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737524", "map_id": "Q9UT25", "name": "AANAT", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC9.02c", "map_id": "SPAC9.02c", "name": "AANAT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741986", "map_id": "none", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524028", "map_id": "CHEBI:17504", "name": "1-acyl LPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10741994", "map_id": "none", "name": "PC is hydrolyzed to 2-acyl LPC by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_975614", "map_id": "CHEBI:16728", "name": "2-acyl LPC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10742013", "map_id": "none", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10741810", "map_id": "none", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10741770", "map_id": "none", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10742007", "map_id": "none", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10742004", "map_id": "none", "name": "PLA2(5)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10738121", "map_id": "none", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_380598", "map_id": "CHEBI:50157", "name": "HIALD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_380593", "map_id": "CHEBI:27823", "name": "HIAA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10730539", "map_id": "none", "name": "ALDH2 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10742179", "map_id": "none", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1497857", "map_id": "CHEBI:15375", "name": "BH2", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10742177", "map_id": "none", "name": "p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10741760", "map_id": "none", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1474124", "map_id": "CHEBI:18372", "name": "DHNTP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10741757", "map_id": "none", "name": "GCH1 decamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13774", "map_id": "O13774", "name": "GCH1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17A5.13", "map_id": "SPAC17A5.13", "name": "GCH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735967", "map_id": "none", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_189487", "map_id": "CHEBI:15430", "name": "PRIN9", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10735964", "map_id": "none", "name": "2x(FECH:2Fe-2S cluster)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O59786", "map_id": "O59786", "name": "hem15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC320.09", "map_id": "SPCC320.09", "name": "hem15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_391232", "map_id": "CHEBI:27889", "name": "Pb2+", "type": "inhibitor", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10735899", "map_id": "none", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189464", "map_id": "CHEBI:58126", "name": "PBG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_189449", "map_id": "CHEBI:57845", "name": "HMBL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735896", "map_id": "none", "name": "HMBS:DIPY", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:36319", "map_id": "CHEBI:36319", "name": "CHEBI:36319", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09899", "map_id": "Q09899", "name": "hem3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC24B11.13", "map_id": "SPAC24B11.13", "name": "hem3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10747163", "map_id": "none", "name": "ABCC2 transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5679042", "map_id": "none", "name": "BMG,BDG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:16427", "map_id": "CHEBI:16427", "name": "CHEBI:16427", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:18392", "map_id": "CHEBI:18392", "name": "CHEBI:18392", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5679034", "map_id": "none", "name": "BMG,BDG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10735981", "map_id": "none", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_190157", "map_id": "CHEBI:28766", "name": "URO1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_190128", "map_id": "CHEBI:28607", "name": "COPRO1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735926", "map_id": "none", "name": "2xUROD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9USJ5", "map_id": "Q9USJ5", "name": "hem12", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC4B3.05c", "map_id": "SPCC4B3.05c", "name": "hem12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735909", "map_id": "none", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_189411", "map_id": "CHEBI:15439", "name": "COPRO3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189480", "map_id": "CHEBI:16526", "name": "CO2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_189478", "map_id": "CHEBI:15435", "name": "PPGEN9", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10735906", "map_id": "none", "name": "2xCPO", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q9UTE2", "map_id": "Q9UTE2", "name": "hem13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC222.11", "map_id": "SPAC222.11", "name": "hem13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735939", "map_id": "none", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189489", "map_id": "CHEBI:356416", "name": "dALA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735936", "map_id": "none", "name": "8x(ALAD:Zn2+)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10735975", "map_id": "none", "name": "UROS transforms HMB to URO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189407", "map_id": "CHEBI:15437", "name": "URO3", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10735972", "map_id": "P87214", "name": "ups1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC31G5.08", "map_id": "SPAC31G5.08", "name": "ups1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735929", "map_id": "none", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189455", "map_id": "CHEBI:15439", "name": "COPRO3", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10743681", "map_id": "none", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2995328", "map_id": "CHEBI:24480", "name": "heme O", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10743678", "map_id": "Q9Y7Y4", "name": "cox10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPBC365.02c", "map_id": "SPBC365.02c", "name": "cox10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735957", "map_id": "none", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_189466", "map_id": "CHEBI:356416", "name": "dALA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10735954", "map_id": "none", "name": "ALAS1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "O14092", "map_id": "O14092", "name": "hem1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2F3.09", "map_id": "SPAC2F3.09", "name": "hem1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10735979", "map_id": "none", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_190173", "map_id": "CHEBI:27889", "name": "Pb2+", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_10735977", "map_id": "none", "name": "8xALAD:Pb2+:Zn2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10735919", "map_id": "none", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_189463", "map_id": "CHEBI:15430", "name": "PRIN9", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10735916", "map_id": "none", "name": "2xPPOX:FAD", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q10062", "map_id": "Q10062", "name": "hem14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1F5.07c", "map_id": "SPAC1F5.07c", "name": "hem14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757699", "map_id": "none", "name": "ABCC1 transports BIL from cytosol to extracellular region (blood)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_189386", "map_id": "CHEBI:16990", "name": "BIL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9661418", "map_id": "CHEBI:16990", "name": "BIL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10743689", "map_id": "none", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_2995348", "map_id": "CHEBI:24479", "name": "heme A", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10743686", "map_id": "Q10361", "name": "etp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPAC22E12.10c", "map_id": "SPAC22E12.10c", "name": "etp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757253", "map_id": "none", "name": "PEX19:class I PMP binds PEX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10757231", "map_id": "none", "name": "PEX19:class I PMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94516", "map_id": "O94516", "name": "pex16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.15c", "map_id": "SPBC646.15c", "name": "pex16", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10333", "map_id": "Q10333", "name": "pex11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC582.09", "map_id": "SPBC582.09", "name": "pex11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7J5", "map_id": "Q9P7J5", "name": "ATAD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC24B10.10c", "map_id": "SPCC24B10.10c", "name": "ATAD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14142", "map_id": "O14142", "name": "sym1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3G6.05", "map_id": "SPAC3G6.05", "name": "sym1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USZ8", "map_id": "Q9USZ8", "name": "fis1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC11G11.01", "map_id": "SPBC11G11.01", "name": "fis1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10244", "map_id": "Q10244", "name": "PXMP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4G9.14", "map_id": "SPAC4G9.14", "name": "PXMP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10485", "map_id": "Q10485", "name": "PEX19", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17C9.14", "map_id": "SPAC17C9.14", "name": "PEX19", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10738205", "map_id": "O14017", "name": "PEX3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "false" }, { "id": "SPAC29A4.14c", "map_id": "SPAC29A4.14c", "name": "PEX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757233", "map_id": "none", "name": "PEX3:PEX19:class I PMP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "O14017", "map_id": "O14017", "name": "PEX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757255", "map_id": "none", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757189", "map_id": "Q10485", "name": "PEX19", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10757229", "map_id": "none", "name": "Class I Peroxisomal Membrane Proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757251", "map_id": "none", "name": "PEX3:PEX19:class I PMP dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane" }, { "id": "species_10757249", "map_id": "none", "name": "Class I Peroxisomal Membrane Proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17947", "compartment_display": "peroxisomal membrane", "complex": "true" }, { "id": "reaction_10738119", "map_id": "none", "name": "loading of Serotonin in synaptic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_374932", "compartment_display": "clathrin-sculpted monoamine transport vesicle lumen" }, { "id": "species_380585", "map_id": "CHEBI:28790", "name": "5HT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_374932", "compartment_display": "clathrin-sculpted monoamine transport vesicle lumen", "complex": "false" }, { "id": "species_10737993", "map_id": "O74852", "name": "SLC18A2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_374940", "compartment_display": "clathrin-sculpted monoamine transport vesicle membrane", "complex": "false" }, { "id": "reaction_10757333", "map_id": "none", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757329", "map_id": "Q9P7I2", "name": "cmk1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPACUNK12.02c", "map_id": "SPACUNK12.02c", "name": "cmk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757331", "map_id": "none", "name": "CAMK1:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P7I2", "map_id": "Q9P7I2", "name": "cmk1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757822", "map_id": "none", "name": "COMT binds COMT Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_9679778", "map_id": "none", "name": "COMT inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=6646", "map_id": "LigandDisplayForward?ligandId=6646", "name": "LigandDisplayForward?ligandId=6646", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=6647", "map_id": "LigandDisplayForward?ligandId=6647", "name": "LigandDisplayForward?ligandId=6647", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8988", "map_id": "LigandDisplayForward?ligandId=8988", "name": "LigandDisplayForward?ligandId=8988", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10738036", "map_id": "none", "name": "Homologues of COMT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10738039", "map_id": "none", "name": "COMT:COMT inhibitors", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10738044", "map_id": "none", "name": "COMT transfers Met to DOPAC to form HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9677997", "map_id": "CHEBI:41941", "name": "DOPAC", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9677992", "map_id": "CHEBI:545959", "name": "HVA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10738041", "map_id": "none", "name": "COMT transfers Met to DA to form 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_159362", "map_id": "CHEBI:18243", "name": "DA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8954997", "map_id": "CHEBI:1582", "name": "3MT", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10737996", "map_id": "none", "name": "Loading of dopamine into synaptic veiscles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_374932", "compartment_display": "clathrin-sculpted monoamine transport vesicle lumen" }, { "id": "reaction_10757324", "map_id": "none", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757317", "map_id": "none", "name": "CaMKK:CALM1:4xCa2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757321", "map_id": "none", "name": "p-CaMKK:CALM1:4xCa2+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756407", "map_id": "none", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756404", "map_id": "none", "name": "Homologues of LRTOMT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10757358", "map_id": "none", "name": "SPHK1 phosphorylates sphingosine in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_1606609", "map_id": "CHEBI:16393", "name": "SPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_5218688", "map_id": "CHEBI:37550", "name": "S1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10737078", "map_id": "none", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10737066", "map_id": "none", "name": "myristoylated eNOS dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737076", "map_id": "none", "name": "myristoylated eNOS dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10737226", "map_id": "none", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10737196", "map_id": "none", "name": "Homologues of 2xPalmC-MyrG-NOS3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "species_10736995", "map_id": "none", "name": "palmitoylated, myristoylated eNOS dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10737204", "map_id": "none", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10737064", "map_id": "none", "name": "Homologues of MyrG-NOS3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737201", "map_id": "O74384", "name": "erf2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "SPBC3H7.09", "map_id": "SPBC3H7.09", "name": "erf2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737214", "map_id": "none", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737212", "map_id": "none", "name": "Homologues of NOS3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_184174", "map_id": "CHEBI:15532", "name": "MYS-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10737224", "map_id": "none", "name": "depalmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_76168", "map_id": "CHEBI:15756", "name": "PALM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17941", "compartment_display": "early endosome", "complex": "false" }, { "id": "reaction_10742182", "map_id": "none", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10740054", "map_id": "none", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10740042", "map_id": "none", "name": "Platelet alpha granule membrane components that are released on degranulation", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114510", "compartment_display": "platelet alpha granule membrane", "complex": "true" }, { "id": "O13809", "map_id": "O13809", "name": "CYB5R1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17H9.12c", "map_id": "SPAC17H9.12c", "name": "CYB5R1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87178", "map_id": "P87178", "name": "TMX3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3D6.13c", "map_id": "SPBC3D6.13c", "name": "TMX3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740052", "map_id": "none", "name": "Platelet alpha granule membrane components that are released on degranulation", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10734544", "map_id": "none", "name": "Activation of conventional Protein Kinase C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734522", "map_id": "none", "name": "Protein Kinase C, conventional", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10740115", "map_id": "none", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740085", "map_id": "none", "name": "Platelet releasate cytosolic proteins", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94590", "map_id": "O94590", "name": "phospho-sec1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42914", "map_id": "O42914", "name": "HABP4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16A3.08c", "map_id": "SPBC16A3.08c", "name": "HABP4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14301", "map_id": "O14301", "name": "WDR1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC9G1.05", "map_id": "SPAC9G1.05", "name": "WDR1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740113", "map_id": "none", "name": "Platelet releasate cytosolic proteins", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10740026", "map_id": "none", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10740020", "map_id": "none", "name": "Platelet dense granule content", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114524", "compartment_display": "platelet dense granule lumen", "complex": "true" }, { "id": "O94740", "map_id": "O94740", "name": "cdc37", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC9B6.10", "map_id": "SPBC9B6.10", "name": "cdc37", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740024", "map_id": "none", "name": "Platelet dense granule content", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10739124", "map_id": "none", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_114584", "compartment_display": "platelet dense granule membrane" }, { "id": "species_114565", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_114524", "compartment_display": "platelet dense granule lumen", "complex": "false" }, { "id": "species_10739121", "map_id": "none", "name": "Homologues of ABCC4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114584", "compartment_display": "platelet dense granule membrane", "complex": "true" }, { "id": "reaction_10740013", "map_id": "none", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10739997", "map_id": "none", "name": "Platelet alpha granule contents", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_114506", "compartment_display": "platelet alpha granule lumen", "complex": "true" }, { "id": "O13998", "map_id": "O13998", "name": "OLA1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC27E2.03c", "map_id": "SPAC27E2.03c", "name": "OLA1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740011", "map_id": "none", "name": "Platelet alpha granule contents", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "reaction_10736228", "map_id": "none", "name": "Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_171126", "map_id": "CHEBI:17855", "name": "TAGs", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_174602", "map_id": "CHEBI:15904", "name": "LCFAs", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "species_174675", "map_id": "CHEBI:18035", "name": "DAGs", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10736220", "map_id": "none", "name": "dimerized CEL:bile salt complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "Q8TFG4", "map_id": "Q8TFG4", "name": "CEL", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB18E9.04c", "map_id": "SPAPB18E9.04c", "name": "CEL", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16755", "map_id": "CHEBI:16755", "name": "CHEBI:16755", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16359", "map_id": "CHEBI:16359", "name": "CHEBI:16359", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755696", "map_id": "none", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_8878780", "map_id": "CHEBI:7794", "name": "phosphate monoester", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_8878776", "map_id": "CHEBI:30879", "name": "Alcohol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_10755693", "map_id": "none", "name": "ALPI:2Ca2+:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10736223", "map_id": "none", "name": "Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_171076", "map_id": "CHEBI:17002", "name": "CHEST", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_171149", "map_id": "CHEBI:16113", "name": "CHOL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10736226", "map_id": "none", "name": "Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "reaction_10757949", "map_id": "none", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757914", "map_id": "none", "name": "Homologues of RND2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10757916", "map_id": "none", "name": "RND2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10740224", "map_id": "none", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_548809", "map_id": "CHEBI:50570", "name": "TOD-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428139", "map_id": "CHEBI:15541", "name": "ST-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740221", "map_id": "none", "name": "TECR,TECRL", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O94511", "map_id": "O94511", "name": "TECR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC646.07c", "map_id": "SPBC646.07c", "name": "TECR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740231", "map_id": "none", "name": "ACSL3,4 ligate CoA to AA to form AA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29768", "map_id": "CHEBI:15843", "name": "AA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_548819", "map_id": "CHEBI:15514", "name": "AA-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740228", "map_id": "none", "name": "ACSL3,4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10747097", "map_id": "none", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5676631", "map_id": "CHEBI:15456", "name": "VLC3HA-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5676634", "map_id": "CHEBI:50998", "name": "2,3-TE-CoA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10747094", "map_id": "none", "name": "PTPLs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O14346", "map_id": "O14346", "name": "PTPLB", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19C2.15c", "map_id": "SPBC19C2.15c", "name": "PTPLB", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736922", "map_id": "none", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10736919", "map_id": "none", "name": "Homologues of ACSL3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10738479", "map_id": "none", "name": "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10738476", "map_id": "none", "name": "PLC beta1,2,3:G-alpha(q):GTP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10734981", "map_id": "none", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734975", "map_id": "none", "name": "AMPK heterotrimer (inactive)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10734979", "map_id": "none", "name": "AMPK heterotrimer:AMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733346", "map_id": "none", "name": "Newly Formed Phosphodiester Bond Stabilized and PPi Released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733344", "map_id": "none", "name": "Pol II Initiation complex with phosphodiester-PPi intermediate", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733338", "map_id": "none", "name": "NTP Binds Active Site of RNA Polymerase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733336", "map_id": "none", "name": "Pol II initiation complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733348", "map_id": "none", "name": "Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10743710", "map_id": "none", "name": "PIAS4 SUMOylates TP53BP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743702", "map_id": "none", "name": "SUMO1:TP53BP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10743707", "map_id": "O94451", "name": "pli1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10744668", "map_id": "none", "name": "UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744646", "map_id": "none", "name": "Homologues of FOXL2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O43058", "map_id": "O43058", "name": "sep1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4C3.12", "map_id": "SPBC4C3.12", "name": "sep1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13606", "map_id": "O13606", "name": "mei4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC32H8.11", "map_id": "SPBC32H8.11", "name": "mei4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744663", "map_id": "none", "name": "3SUMO1:FOXL2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10744665", "map_id": "none", "name": "UBE2I,PIAS1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10751307", "map_id": "none", "name": "ATM phosphorylates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10751295", "map_id": "none", "name": "Homologues of DYRK2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q09815", "map_id": "Q09815", "name": "ppk5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC16C9.07", "map_id": "SPAC16C9.07", "name": "ppk5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09690", "map_id": "Q09690", "name": "pom1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC2F7.03c", "map_id": "SPAC2F7.03c", "name": "pom1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10751305", "map_id": "none", "name": "Homologues of p-T106,S442-DYRK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10751322", "map_id": "none", "name": "MDM2 ubiquitinates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10751315", "map_id": "none", "name": "Homologues of PolyUb-DYRK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10751319", "map_id": "none", "name": "p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10752579", "map_id": "none", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10752575", "map_id": "none", "name": "Casein kinase II", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10752577", "map_id": "none", "name": "CK2:FACT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745446", "map_id": "none", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_5221122", "map_id": "CHEBI:29089", "name": "1,2-diacyl-glycerol 3-phosphate", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_5221124", "map_id": "CHEBI:17815", "name": "DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10744759", "map_id": "Q9UUJ6", "name": "ned1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "reaction_10744778", "map_id": "none", "name": "CTDNEP1:CNEP1R1 dephosphorylates LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10744753", "map_id": "Q9UUJ6", "name": "phospho-ned1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744775", "map_id": "none", "name": "CTDNEP1:CNEP1R1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "Q9USQ0", "map_id": "Q9USQ0", "name": "spo7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC902.03", "map_id": "SPBC902.03", "name": "spo7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59718", "map_id": "O59718", "name": "nem1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3B8.10c", "map_id": "SPBC3B8.10c", "name": "nem1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742056", "map_id": "none", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500603", "map_id": "CHEBI:16732", "name": "CDP-ETA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10742053", "map_id": "none", "name": "CEPT1/EPT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O13901", "map_id": "O13901", "name": "EPT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22A12.10", "map_id": "SPAC22A12.10", "name": "EPT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742027", "map_id": "none", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1483256", "map_id": "CHEBI:17517", "name": "PG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1498740", "map_id": "CHEBI:62747", "name": "1-acyl LPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10741849", "map_id": "none", "name": "PLA2(1)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742073", "map_id": "none", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426955", "map_id": "CHEBI:17962", "name": "CDP-DAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10742070", "map_id": "none", "name": "CDIPT:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q10153", "map_id": "Q10153", "name": "pis1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1D4.08", "map_id": "SPAC1D4.08", "name": "pis1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742110", "map_id": "none", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524071", "map_id": "CHEBI:36700", "name": "PCho", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1524060", "map_id": "CHEBI:16436", "name": "CDP-Cho", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10742107", "map_id": "none", "name": "PCYT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O74975", "map_id": "O74975", "name": "PCYT1A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1827.02c", "map_id": "SPCC1827.02c", "name": "PCYT1A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742173", "map_id": "none", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1498751", "map_id": "CHEBI:16000", "name": "ETA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428686", "map_id": "CHEBI:17553", "name": "PETA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10742170", "map_id": "none", "name": "CHK/ETNK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10276", "map_id": "Q10276", "name": "ETNK1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13G7.12c", "map_id": "SPAC13G7.12c", "name": "ETNK1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749967", "map_id": "none", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5696449", "map_id": "CHEBI:17408", "name": "MAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_6782195", "map_id": "CHEBI:17984", "name": "Acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10742021", "map_id": "none", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1500594", "map_id": "CHEBI:17855", "name": "TAG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10741961", "map_id": "none", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524042", "map_id": "CHEBI:17517", "name": "PG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524085", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1524027", "map_id": "CHEBI:62747", "name": "1-acyl LPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10741958", "map_id": "none", "name": "PLA2G", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10742032", "map_id": "none", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498730", "map_id": "CHEBI:27923", "name": "2-acyl LPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10742029", "map_id": "none", "name": "PLA2(14)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10753720", "map_id": "none", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10753715", "map_id": "O74850", "name": "dga1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10741907", "map_id": "none", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10749937", "map_id": "none", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_5696069", "map_id": "CHEBI:30616", "name": "ATP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5696066", "map_id": "none", "name": "MAG,DAG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "species_5696026", "map_id": "CHEBI:456216", "name": "ADP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_5696037", "map_id": "none", "name": "LPA,PA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "species_1500590", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10749934", "map_id": "none", "name": "AGK:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "O94624", "map_id": "O94624", "name": "tim54", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1347.04", "map_id": "SPBC1347.04", "name": "tim54", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741782", "map_id": "none", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498728", "map_id": "CHEBI:17389", "name": "2-MAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1500593", "map_id": "CHEBI:35366", "name": "fatty acid", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10741779", "map_id": "none", "name": "MGLL dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O94305", "map_id": "O94305", "name": "mgl1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742017", "map_id": "none", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498733", "map_id": "CHEBI:28914", "name": "1-acyl LPI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10742037", "map_id": "none", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1498737", "map_id": "CHEBI:62746", "name": "2-acyl LPI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10742034", "map_id": "none", "name": "PLA2(13)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10741888", "map_id": "none", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10741814", "map_id": "O42916", "name": "ale1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10742002", "map_id": "none", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524047", "map_id": "CHEBI:27923", "name": "2-acyl LPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10741852", "map_id": "none", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_1524103", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_1500580", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "reaction_10742010", "map_id": "none", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524069", "map_id": "CHEBI:60430", "name": "MLCL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_1524081", "map_id": "CHEBI:28494", "name": "CL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10733368", "map_id": "O94361", "name": "LCLAT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC428.14", "map_id": "SPBC428.14", "name": "LPGAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742120", "map_id": "none", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_426755", "map_id": "CHEBI:16337", "name": "PA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10742117", "map_id": "none", "name": "CDS1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9P381", "map_id": "Q9P381", "name": "CDS2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741807", "map_id": "none", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524038", "map_id": "CHEBI:17984", "name": "acyl-CoA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10741804", "map_id": "O13899", "name": "CRLS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPAC22A12.08c", "map_id": "SPAC22A12.08c", "name": "CRLS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741890", "map_id": "none", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10755107", "map_id": "none", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10755104", "map_id": "none", "name": "Homologues of PITPNM3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q7LKZ6", "map_id": "Q7LKZ6", "name": "PITPNM3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1020.13c", "map_id": "SPCC1020.13c", "name": "PITPNM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742133", "map_id": "none", "name": "PE is methylated to PC by PEMT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10742130", "map_id": "O74827", "name": "cho1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC337.16", "map_id": "SPBC337.16", "name": "cho1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741817", "map_id": "none", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10741910", "map_id": "none", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "reaction_10742063", "map_id": "none", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_1524057", "map_id": "CHEBI:17815", "name": "DAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "false" }, { "id": "species_10742060", "map_id": "none", "name": "CHPT1:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10742015", "map_id": "none", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_1524080", "map_id": "CHEBI:60431", "name": "DLCL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10741893", "map_id": "none", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10741772", "map_id": "O94361", "name": "LPGAT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10741885", "map_id": "none", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10742091", "map_id": "none", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742088", "map_id": "none", "name": "CHK dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10742153", "map_id": "none", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10742150", "map_id": "none", "name": "PCYT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9UTI6", "map_id": "Q9UTI6", "name": "PCYT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC15E1.05c", "map_id": "SPAC15E1.05c", "name": "PCYT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742094", "map_id": "none", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1524067", "map_id": "CHEBI:60377", "name": "cytidine 5'-monophosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_1524072", "map_id": "CHEBI:28494", "name": "cardiolipin", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "reaction_10741980", "map_id": "none", "name": "MLCL is hydrolyzed to DLCL by PLA2G4A (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane" }, { "id": "species_1498773", "map_id": "CHEBI:60430", "name": "MLCL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_1498753", "map_id": "CHEBI:60431", "name": "DLCL", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "species_10741977", "map_id": "none", "name": "PLA2G4A:Ca2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "true" }, { "id": "reaction_10741902", "map_id": "none", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1500604", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10733396", "map_id": "none", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_76114", "map_id": "CHEBI:15978", "name": "G3P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10733393", "map_id": "none", "name": "GPD1/GPD1L homodimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09845", "map_id": "Q09845", "name": "gpd2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23D3.04c", "map_id": "SPAC23D3.04c", "name": "gpd2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P21696", "map_id": "P21696", "name": "gpd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC215.05", "map_id": "SPBC215.05", "name": "gpd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749957", "map_id": "none", "name": "PXLP-K278-ETNPPL tetramer hydrolyses PETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5696414", "map_id": "CHEBI:17553", "name": "PETA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_113532", "map_id": "CHEBI:15343", "name": "CH3CHO", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10749954", "map_id": "none", "name": "PXLP-K278-ETNPPL tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10741914", "map_id": "none", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10750442", "map_id": "none", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1602447", "map_id": "CHEBI:16975", "name": "1-acyl LPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_1602366", "map_id": "CHEBI:57560", "name": "LCFA(-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10750439", "map_id": "none", "name": "DDHD1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10741991", "map_id": "none", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10742143", "map_id": "none", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10742138", "map_id": "Q09706", "name": "pld1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10741775", "map_id": "none", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "reaction_10733373", "map_id": "none", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10733370", "map_id": "none", "name": "AGPAT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O94361", "map_id": "O94361", "name": "LPGAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755689", "map_id": "none", "name": "ACP6 hydrolyses MYS-LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_8878649", "map_id": "CHEBI:62833", "name": "MYS-LPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_8934414", "map_id": "CHEBI:75562", "name": "1-MMG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10755686", "map_id": "Q9USS6", "name": "ACP6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10742164", "map_id": "none", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10742161", "map_id": "none", "name": "LPIN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9UUJ6", "map_id": "Q9UUJ6", "name": "ned1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742047", "map_id": "none", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10742044", "map_id": "none", "name": "CEPT1:Mg2+/Mn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10756967", "map_id": "none", "name": "RHOT2 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756963", "map_id": "none", "name": "RHOT2 effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9USY7", "map_id": "Q9USY7", "name": "fzo1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1706.03", "map_id": "SPBC1706.03", "name": "fzo1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756965", "map_id": "none", "name": "RHOT2:GTP:RHOT2 effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10756969", "map_id": "none", "name": "RHOT2 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10757850", "map_id": "none", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10757845", "map_id": "none", "name": "RHOF:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10757847", "map_id": "none", "name": "RHOF:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10757896", "map_id": "none", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756838", "map_id": "none", "name": "RHOD GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10752557", "map_id": "none", "name": "ATM phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10737757", "map_id": "O74503", "name": "phospho-spp27", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10752555", "map_id": "O74503", "name": "phospho-spp27", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10755684", "map_id": "none", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10740775", "map_id": "O74448", "name": "pin1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPCC16C4.03", "map_id": "SPCC16C4.03", "name": "pin1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10755677", "map_id": "none", "name": "p-S326-PIP4K2B dimers", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10755682", "map_id": "none", "name": "p-S326-PIP4K2B dimers:PIN1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O74448", "map_id": "O74448", "name": "pin1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737784", "map_id": "none", "name": "Phosphorylation of MDM4 by ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10737774", "map_id": "none", "name": "p-S166,S188-MDM2:MDM4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10737762", "map_id": "none", "name": "p-S166,S188-MDM2:p-S403-MDM4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10751191", "map_id": "none", "name": "MDM2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10752603", "map_id": "none", "name": "AKT phosphorylates KAT6A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10752596", "map_id": "none", "name": "KAT6A:ING5:MEAF6:BRPF1,(2,3)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O14240", "map_id": "O14240", "name": "eaf6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC6F6.09", "map_id": "SPAC6F6.09", "name": "eaf6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74736", "map_id": "O74736", "name": "png2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1709.11c", "map_id": "SPBC1709.11c", "name": "png2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94446", "map_id": "O94446", "name": "phospho-mst1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC637.12c", "map_id": "SPAC637.12c", "name": "phospho-mst1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42871", "map_id": "O42871", "name": "png1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC3G9.08", "map_id": "SPAC3G9.08", "name": "png1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10752601", "map_id": "none", "name": "p-T369-KAT6A:ING5:MEAF6:BRPF1,(2,3)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10752539", "map_id": "none", "name": "MDM2 ubiquitinates phosphorylated MDM4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10737768", "map_id": "none", "name": "p-S166,S188-MDM2:p-S346,S367,S403-MDM4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10752536", "map_id": "none", "name": "PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10751207", "map_id": "none", "name": "TORC2 complex phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10751197", "map_id": "none", "name": "Homologues of SGK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10751205", "map_id": "none", "name": "Homologues of p-S422-SGK1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10751220", "map_id": "none", "name": "PDPK1 phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10751215", "map_id": "none", "name": "Homologues of p-T256,S422-SGK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10752549", "map_id": "none", "name": "MDM2 homodimers auto-ubiquitinate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10751317", "map_id": "none", "name": "p-S166,S188-MDM2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10752546", "map_id": "none", "name": "PolyUb,p-S166,S188-MDM2 homodimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10751189", "map_id": "none", "name": "(CDK1,CDK2):CCNA phosphorylates MDM2 at T218", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10751172", "map_id": "O74503", "name": "phospho-spp27", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10753231", "map_id": "none", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744714", "map_id": "none", "name": "Homologues of ING2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10753229", "map_id": "none", "name": "ING2:PI5P", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10737770", "map_id": "none", "name": "Phosphorylation of MDM4 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10751222", "map_id": "none", "name": "MDM2 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10752543", "map_id": "none", "name": "MDM2 forms homo- or heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10752541", "map_id": "none", "name": "p-S166,S188-MDM2,MDM4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10755680", "map_id": "none", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10755666", "map_id": "none", "name": "PIP4K2B dimers", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10739756", "map_id": "none", "name": "Homologues of p-S207,T211-MAP2K6", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10751218", "map_id": "none", "name": "SGK1 phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10751262", "map_id": "none", "name": "CCNK:CDK12 binds RNA Pol II at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10751226", "map_id": "none", "name": "CCNK:CDK12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10751242", "map_id": "none", "name": "Elongation Complex at DNA Repair Genes", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10751244", "map_id": "none", "name": "CCNK:CDK12:Elongation Complex at DNA Repair Genes", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10751260", "map_id": "none", "name": "CDK12 phosphorylates RNA Pol II CTD at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10751257", "map_id": "none", "name": "CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10751234", "map_id": "none", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734263", "map_id": "O74627", "name": "pch1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10751230", "map_id": "O14098", "name": "lsk1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10751232", "map_id": "none", "name": "CCNK:CDK13", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10751228", "map_id": "none", "name": "CCNK binds CDK12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10751224", "map_id": "O14098", "name": "lsk1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10739697", "map_id": "none", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113539", "map_id": "CHEBI:30089", "name": "CH3COO-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_159448", "map_id": "CHEBI:456215", "name": "AMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10739694", "map_id": "P78773", "name": "ACSS1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPCC191.02c", "map_id": "SPCC191.02c", "name": "ACSS1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730535", "map_id": "none", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30203", "map_id": "CHEBI:16236", "name": "EtOH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29510", "map_id": "CHEBI:15343", "name": "CH3CHO", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730532", "map_id": "none", "name": "alcohol dehydrogenase complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10730567", "map_id": "none", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29416", "map_id": "CHEBI:15366", "name": "CH3COO-", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10730564", "map_id": "P78773", "name": "ACSS2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10745912", "map_id": "none", "name": "DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5490235", "map_id": "none", "name": "AFXBO-CG,AFNBO-CG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:78579", "map_id": "CHEBI:78579", "name": "CHEBI:78579", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:78584", "map_id": "CHEBI:78584", "name": "CHEBI:78584", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5490250", "map_id": "none", "name": "AFXBO-C,AFNBO-C", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:78578", "map_id": "CHEBI:78578", "name": "CHEBI:78578", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:78583", "map_id": "CHEBI:78583", "name": "CHEBI:78583", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730490", "map_id": "none", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10730487", "map_id": "none", "name": "ALDH1A1 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10730542", "map_id": "none", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10749939", "map_id": "none", "name": "ALDH1B1 tetramer oxidises CH3CHO to CH3COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10745935", "map_id": "none", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_5490253", "map_id": "none", "name": "AFXBO-SG,AFNBO-SG", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "true" }, { "id": "CHEBI:78587", "map_id": "CHEBI:78587", "name": "CHEBI:78587", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:78581", "map_id": "CHEBI:78581", "name": "CHEBI:78581", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749510", "map_id": "none", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5692221", "map_id": "CHEBI:48926", "name": "S-HMGSH", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5692249", "map_id": "CHEBI:16225", "name": "S-FGSH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10749507", "map_id": "none", "name": "ADH5:2xZn2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10747760", "map_id": "none", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_5689006", "map_id": "CHEBI:8050", "name": "PHEN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5688995", "map_id": "CHEBI:85505", "name": "4-ethoxyaniline", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5689001", "map_id": "CHEBI:40574", "name": "acetyl group", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10747757", "map_id": "none", "name": "Homologues of AADAC", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10734961", "map_id": "none", "name": "TFAM binds to mitochondrial promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_163305", "map_id": "none", "name": "mitochondrial DNA promoter", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10734957", "map_id": "none", "name": "Homologues of TFAM", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "species_10734959", "map_id": "none", "name": "TFAM:mitochondrial promoter complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10743032", "map_id": "none", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743025", "map_id": "none", "name": "PHF8:Nucleosome with H3K4me2/3:H4K20me1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O94603", "map_id": "O94603", "name": "jhd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC622.16c", "map_id": "SPCC622.16c", "name": "jhd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743029", "map_id": "none", "name": "PHF8:Nucleosome with H3K4me2/3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10758000", "map_id": "none", "name": "RHOC activates endoplasmic reticulum effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10757996", "map_id": "none", "name": "RHOC endoplasmic reticulum effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O42707", "map_id": "O42707", "name": "LMAN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC126.08c", "map_id": "SPCC126.08c", "name": "LMAN1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10484", "map_id": "Q10484", "name": "scs22", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17C9.12", "map_id": "SPAC17C9.12", "name": "scs22", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94401", "map_id": "O94401", "name": "LMAN1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757971", "map_id": "none", "name": "RHOC:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "species_10757998", "map_id": "none", "name": "RHOC:GTP:RHOC endoplasmic reticulum effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10758002", "map_id": "none", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10746673", "map_id": "none", "name": "RHOC:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10756748", "map_id": "none", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756724", "map_id": "none", "name": "RHOC:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10756740", "map_id": "none", "name": "GDIs block activation of RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756674", "map_id": "O14224", "name": "ARHGDIA", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10756738", "map_id": "none", "name": "RHOC:GDP:ARHGDIA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756746", "map_id": "none", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756742", "map_id": "none", "name": "RHOC effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94675", "map_id": "O94675", "name": "C1QBP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC776.07", "map_id": "SPBC776.07", "name": "C1QBP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756744", "map_id": "none", "name": "RHOC:GTP:RHOC effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10736357", "map_id": "none", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196095", "map_id": "CHEBI:17998", "name": "ISCAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_196066", "map_id": "CHEBI:63910", "name": "MePeOH", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736354", "map_id": "none", "name": "Homologues of AKR1B1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10744363", "map_id": "none", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10732874", "map_id": "P09322", "name": "hhf3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744336", "map_id": "P09322", "name": "hhf3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744360", "map_id": "none", "name": "HAT1:RBBP7", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9UTM7", "map_id": "Q9UTM7", "name": "hat1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC139.06", "map_id": "SPAC139.06", "name": "hat1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744059", "map_id": "none", "name": "ATF2 acetylates histone H2B, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744046", "map_id": "none", "name": "Histone H2B, H4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10744056", "map_id": "none", "name": "AcK-replicative histone H2B, H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756972", "map_id": "none", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9022655", "map_id": "CHEBI:138490", "name": "5S,6S-epoxy-18(S)-HEPE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9022660", "map_id": "CHEBI:137038", "name": "18(S)-RvE1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742548", "map_id": "none", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742542", "map_id": "none", "name": "Signal Recognition Particle", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P21565", "map_id": "P21565", "name": "srp54", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC188.06c", "map_id": "SPCC188.06c", "name": "srp54", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74436", "map_id": "O74436", "name": "srp68", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1682.05c", "map_id": "SPCC1682.05c", "name": "srp68", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59787", "map_id": "O59787", "name": "srp72", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC320.10", "map_id": "SPCC320.10", "name": "srp72", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13804", "map_id": "O13804", "name": "SRP9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17H9.07", "map_id": "SPAC17H9.07", "name": "SRP9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94407", "map_id": "O94407", "name": "sec65", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC126.15c", "map_id": "SPCC126.15c", "name": "sec65", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10742544", "map_id": "none", "name": "ribosome:mRNA:polypeptide+signal", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10742546", "map_id": "none", "name": "SRP:polypeptide+signal:ribosome", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10740758", "map_id": "none", "name": "Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740756", "map_id": "none", "name": "mRNA Cleaved by SMG6", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09820", "map_id": "Q09820", "name": "phospho-upf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC16C9.06c", "map_id": "SPAC16C9.06c", "name": "phospho-upf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14338", "map_id": "O14338", "name": "SMG5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2F12.03c", "map_id": "SPBC2F12.03c", "name": "SMG5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74804", "map_id": "O74804", "name": "est1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2D10.13", "map_id": "SPBC2D10.13", "name": "est1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733183", "map_id": "none", "name": "Cap Binding Complex (CBC)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10740705", "map_id": "none", "name": "PP2A (Aalpha:B55alpha:Calpha)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10740725", "map_id": "O74804", "name": "est1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740717", "map_id": "none", "name": "Homologues of SMG5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10740723", "map_id": "none", "name": "Homologues of SMG7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10740674", "map_id": "Q09820", "name": "upf1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740752", "map_id": "Q09820", "name": "phospho-upf1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10740770", "map_id": "none", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740767", "map_id": "none", "name": "SMG1:UPF1:EJC:Translated mRNP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74718", "map_id": "O74718", "name": "sup35", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC584.04", "map_id": "SPCC584.04", "name": "sup35", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13824", "map_id": "O13824", "name": "upf2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC19A8.08", "map_id": "SPAC19A8.08", "name": "upf2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P79063", "map_id": "P79063", "name": "sup45", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1834.01", "map_id": "SPAC1834.01", "name": "sup45", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740754", "map_id": "none", "name": "SMG1:Phosphorylated UPF1:EJC:Translated mRNP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10740765", "map_id": "none", "name": "SMG6 hydrolyzes mRNA with premature termination codon", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740762", "map_id": "none", "name": "Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10755910", "map_id": "none", "name": "SH3PXD2A binds ADAM12,ADAM15,ADAM19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10755902", "map_id": "O13766", "name": "mde10", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10755900", "map_id": "none", "name": "SH3PXD2A:PI(3,4)P2", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "P40996", "map_id": "P40996", "name": "phospho-scd2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22H10.07", "map_id": "SPAC22H10.07", "name": "phospho-scd2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10755908", "map_id": "none", "name": "SH3PXD2A:PI(3,4)P2:ADAM12,ADAM15,ADAM19", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10740377", "map_id": "none", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29970", "map_id": "CHEBI:16946", "name": "L-KYN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_893615", "map_id": "CHEBI:17442", "name": "AP-DOBu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8939576", "map_id": "none", "name": "I3LACT, I3PROPA", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:55528", "map_id": "CHEBI:55528", "name": "CHEBI:55528", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:43580", "map_id": "CHEBI:43580", "name": "CHEBI:43580", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749439", "map_id": "none", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10749434", "map_id": "none", "name": "UCHL1,UCHL3:Ub-Lys", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10749436", "map_id": "none", "name": "UCHL1,UCHL3:Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10744634", "map_id": "none", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744632", "map_id": "none", "name": "SUMO1:PIAS4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750477", "map_id": "none", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_6788753", "map_id": "CHEBI:86019", "name": "S-FARN-Cys", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6788758", "map_id": "CHEBI:87167", "name": "S-FARN-CME", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10750474", "map_id": "none", "name": "ICMT:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "P87014", "map_id": "P87014", "name": "mam4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC10F6.12c", "map_id": "SPAC10F6.12c", "name": "mam4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734835", "map_id": "none", "name": "phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8855657", "map_id": "CHEBI:15935", "name": "N-acetylglucosaminyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10734832", "map_id": "none", "name": "GPI-GnT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O59802", "map_id": "O59802", "name": "gpi2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC550.04c", "map_id": "SPCC550.04c", "name": "gpi2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USW6", "map_id": "Q9USW6", "name": "dpm2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC21B10.11", "map_id": "SPBC21B10.11", "name": "dpm2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87172", "map_id": "P87172", "name": "gpi3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3D6.07", "map_id": "SPBC3D6.07", "name": "gpi3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7L7", "map_id": "Q9Y7L7", "name": "gpi15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC685.05", "map_id": "SPBC685.05", "name": "gpi15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13904", "map_id": "O13904", "name": "mug84", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22A12.13", "map_id": "SPAC22A12.13", "name": "mug84", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14357", "map_id": "O14357", "name": "gpi1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC30D10.11", "map_id": "SPBC30D10.11", "name": "gpi1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744958", "map_id": "none", "name": "PIAS2-2 SUMOylates SUZ12 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744943", "map_id": "none", "name": "Homologues of SUZ12", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O94522", "map_id": "O94522", "name": "rsc7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1281.05", "map_id": "SPCC1281.05", "name": "rsc7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74792", "map_id": "O74792", "name": "snf59", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC26H8.09c", "map_id": "SPBC26H8.09c", "name": "snf59", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744956", "map_id": "none", "name": "SUMO1:SUZ12", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10743728", "map_id": "O94451", "name": "pli1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10745032", "map_id": "none", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745022", "map_id": "P07799", "name": "top1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC1703.14c", "map_id": "SPBC1703.14c", "name": "top1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745030", "map_id": "none", "name": "SUMO1:TOP1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P07799", "map_id": "P07799", "name": "top1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739546", "map_id": "none", "name": "Addition of the first glucose to the N-glycan precursor by ALG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449371", "map_id": "CHEBI:37637", "name": "(GlcNAc)2 (Man)9 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_532542", "map_id": "CHEBI:15812", "name": "DbGP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449311", "map_id": "CHEBI:16214", "name": "DOLP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449649", "map_id": "CHEBI:59081", "name": "(Glc)1 (GlcNAc)2 (Man)9 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10739543", "map_id": "O43053", "name": "alg6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC342.01c", "map_id": "SPBC342.01c", "name": "alg6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10740200", "map_id": "none", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_532562", "map_id": "CHEBI:17369", "name": "Man6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740197", "map_id": "O43014", "name": "pmi40", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC2G2.16", "map_id": "SPBC2G2.16", "name": "pmi40", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734722", "map_id": "none", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734718", "map_id": "P40921", "name": "tef3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC29A4.02c", "map_id": "SPAC29A4.02c", "name": "tef3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734713", "map_id": "O74173", "name": "tef5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC1450.04", "map_id": "SPCC1450.04", "name": "tef5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734711", "map_id": "O74173", "name": "tef5", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734720", "map_id": "none", "name": "eEF1B complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P40921", "map_id": "P40921", "name": "tef3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74173", "map_id": "O74173", "name": "tef5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755736", "map_id": "none", "name": "PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10731529", "map_id": "O74892", "name": "rps2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10755728", "map_id": "O74892", "name": "rps2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10755733", "map_id": "O13648", "name": "rmt3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC8D2.10c", "map_id": "SPBC8D2.10c", "name": "rmt3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744624", "map_id": "none", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10730920", "map_id": "P24782", "name": "dbp2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBP8B7.16c", "map_id": "SPBP8B7.16c", "name": "dbp2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744622", "map_id": "none", "name": "SUMO1:DDX5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P24782", "map_id": "P24782", "name": "dbp2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750113", "map_id": "none", "name": "USP19 binds HIF1A,BIRC2,BIRC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10750109", "map_id": "O60139", "name": "ubp4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC18H10.08c", "map_id": "SPBC18H10.08c", "name": "ubp4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750111", "map_id": "none", "name": "USP19:HIF1A,BIRC2,BIRC3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O60139", "map_id": "O60139", "name": "ubp4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744889", "map_id": "none", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744887", "map_id": "none", "name": "SUMO1:HIST1H4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750212", "map_id": "none", "name": "YOD1 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10745608", "map_id": "Q9P3A7", "name": "cdc48", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10750208", "map_id": "O13974", "name": "otu1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC24C9.14", "map_id": "SPAC24C9.14", "name": "otu1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750210", "map_id": "none", "name": "YOD1:VCP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13974", "map_id": "O13974", "name": "otu1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737483", "map_id": "none", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_204628", "map_id": "CHEBI:15725", "name": "1,3-diaminopropane", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737463", "map_id": "none", "name": "Dhp-K50-EIF5A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UST4", "map_id": "Q9UST4", "name": "tif51b", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC336.10c", "map_id": "SPBC336.10c", "name": "tif51b", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P56289", "map_id": "P56289", "name": "tif51a", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC26H5.10c", "map_id": "SPAC26H5.10c", "name": "tif51a", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_204635", "map_id": "CHEBI:16610", "name": "SPM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737473", "map_id": "none", "name": "EIF5A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737480", "map_id": "none", "name": "DHPS tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94337", "map_id": "O94337", "name": "DHPS", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1271.04c", "map_id": "SPBC1271.04c", "name": "DHPS", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746712", "map_id": "none", "name": "ADRM1 binds 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746683", "map_id": "Q9Y7Y6", "name": "rpn1301", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC342.04", "map_id": "SPBC342.04", "name": "rpn1301", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746685", "map_id": "none", "name": "ADRM1:26S proteasome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9Y7Y6", "map_id": "Q9Y7Y6", "name": "rpn1301", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755788", "map_id": "none", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10755776", "map_id": "Q9P3A7", "name": "cdc48", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10755785", "map_id": "none", "name": "Homologues of VCPKMT", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13926", "map_id": "O13926", "name": "VCPKMT", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23C4.06c", "map_id": "SPAC23C4.06c", "name": "VCPKMT", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87241", "map_id": "P87241", "name": "rib2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC4G3.16", "map_id": "SPCC4G3.16", "name": "rib2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750092", "map_id": "none", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10750085", "map_id": "none", "name": "USP37:RUVLB1:PSMC5:PolyUb-CCNA1,PolyUb-CCNA2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9C0X6", "map_id": "Q9C0X6", "name": "rvb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB8E5.09", "map_id": "SPAPB8E5.09", "name": "rvb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750089", "map_id": "none", "name": "USP37:RUVLB1:PSMC5:CCNA1,CCNA2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10748683", "map_id": "none", "name": "PolyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746689", "map_id": "none", "name": "ADRM1:26S proteaseome binds UCHL5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746678", "map_id": "Q9UUB6", "name": "uch2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC409.06", "map_id": "SPBC409.06", "name": "uch2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746687", "map_id": "none", "name": "ADRM1:26S proteasome:UCHL5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UUB6", "map_id": "Q9UUB6", "name": "uch2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734866", "map_id": "none", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8855659", "map_id": "CHEBI:53056", "name": "mannose (a1-4) glucosaminyl-acyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8855663", "map_id": "none", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10734863", "map_id": "Q8WZK2", "name": "its8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC839.08c", "map_id": "SPBC839.08c", "name": "its8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744744", "map_id": "none", "name": "SUMOylation of HIPK2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744734", "map_id": "Q9P6P3", "name": "ppk15", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC823.03", "map_id": "SPAC823.03", "name": "ppk15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744742", "map_id": "none", "name": "SUMO1:HIPK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9P6P3", "map_id": "Q9P6P3", "name": "ppk15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745739", "map_id": "none", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10745719", "map_id": "O14460", "name": "eft201", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745706", "map_id": "O14460", "name": "eft201", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_353106", "map_id": "CHEBI:17509", "name": "MTAD", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745736", "map_id": "none", "name": "DPH1:DPH2:DPH3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10206", "map_id": "Q10206", "name": "dph2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17D1.02", "map_id": "SPBC17D1.02", "name": "dph2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UT33", "map_id": "Q9UT33", "name": "dph3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC8F11.02c", "map_id": "SPAC8F11.02c", "name": "dph3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59713", "map_id": "O59713", "name": "dph1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739520", "map_id": "none", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449312", "map_id": "CHEBI:59088", "name": "(GlcNAc)2 (Man)7 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449229", "map_id": "CHEBI:15809", "name": "DOLP-Man", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449365", "map_id": "CHEBI:59091", "name": "(GlcNAc)2 (Man)8 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10739517", "map_id": "Q9USD4", "name": "alg12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC1734.12c", "map_id": "SPBC1734.12c", "name": "alg12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739488", "map_id": "none", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449298", "map_id": "CHEBI:53022", "name": "(GlcNAc)2 (Man)5 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449315", "map_id": "CHEBI:53023", "name": "(GlcNAc)2 (Man)6 (PP-Dol)1", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10739485", "map_id": "Q9Y7I4", "name": "alg3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC7D4.06c", "map_id": "SPAC7D4.06c", "name": "alg3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734874", "map_id": "none", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8855667", "map_id": "CHEBI:53058", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8855656", "map_id": "CHEBI:53059", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_162872", "map_id": "CHEBI:16214", "name": "dolichyl phosphate", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10734871", "map_id": "Q9USN0", "name": "gpi10", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPCC16A11.06c", "map_id": "SPCC16A11.06c", "name": "gpi10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750032", "map_id": "none", "name": "USP12, USP26 deubiquitinate AR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10750027", "map_id": "none", "name": "USP12:WDR48:WDR20,USP26:PolyUb-AR", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q10437", "map_id": "Q10437", "name": "bun62", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC12B10.03", "map_id": "SPAC12B10.03", "name": "bun62", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750029", "map_id": "none", "name": "USP12:WDR48:WDR20,USP26:AR", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745006", "map_id": "none", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744996", "map_id": "P08096", "name": "top2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC1A4.03c", "map_id": "SPBC1A4.03c", "name": "top2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745004", "map_id": "none", "name": "SUMO1:TOP2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P08096", "map_id": "P08096", "name": "top2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737507", "map_id": "none", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737497", "map_id": "none", "name": "Hyp-K50-EIF5A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10737504", "map_id": "none", "name": "DOHH:Fe++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P6K9", "map_id": "Q9P6K9", "name": "lia1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC30C2.02", "map_id": "SPAC30C2.02", "name": "lia1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744694", "map_id": "none", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744692", "map_id": "none", "name": "SUMO1:K14-UBE2I", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750295", "map_id": "none", "name": "USP17 deubiquitinates SUDS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10750290", "map_id": "none", "name": "USP17:K63polyUb-SUDS3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O74442", "map_id": "O74442", "name": "ubp16", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750292", "map_id": "none", "name": "USP17:SUDS3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10748291", "map_id": "none", "name": "K63polyUb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734882", "map_id": "none", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8855661", "map_id": "CHEBI:24275", "name": "glucosaminyl-PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10734879", "map_id": "Q9HDW9", "name": "gpi12", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAPB2B4.01c", "map_id": "SPAPB2B4.01c", "name": "gpi12", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10748686", "map_id": "none", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747837", "map_id": "none", "name": "USP7:PolyUb-TP53,PolyUb-MDM2,PolyUb-MDM4,PolyUb-FOXO4,PolyUb-PTEN", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10747843", "map_id": "none", "name": "USP7:TP53,MDM2,MDM4,FOXO4,PTEN", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734803", "map_id": "none", "name": "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_162860", "map_id": "CHEBI:15820", "name": "GDP-Man", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_162681", "map_id": "CHEBI:15809", "name": "DOLP-Man", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10734800", "map_id": "none", "name": "DPM1:DPM2:DPM3", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O94633", "map_id": "O94633", "name": "dpm3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1677.02", "map_id": "SPBC1677.02", "name": "dpm3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14466", "map_id": "O14466", "name": "dpm1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC31G5.16c", "map_id": "SPAC31G5.16c", "name": "dpm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10752208", "map_id": "none", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10752186", "map_id": "none", "name": "ETF1 dimer:eRF3:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10752193", "map_id": "none", "name": "Me-Q185-ETF1 dimer:eRF3:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10744991", "map_id": "none", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744524", "map_id": "O59702", "name": "clr6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744989", "map_id": "none", "name": "SUMO1:HDAC2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10744684", "map_id": "none", "name": "PIAS2-1 SUMOylates PARK7 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744673", "map_id": "Q10356", "name": "hsp3106", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744681", "map_id": "none", "name": "SUMO1:PARK7", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10750010", "map_id": "none", "name": "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10750001", "map_id": "none", "name": "USP17:PolyUb-RCE1, PolyUb-CDC25A, PolyUb-DDX58, PolyUb-IFIH1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94448", "map_id": "O94448", "name": "RCE1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750007", "map_id": "none", "name": "USP17L1,USP17L2:RCE1, CDC25A, DDX58, IFIH1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10734890", "map_id": "none", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10734887", "map_id": "Q09712", "name": "gpi18", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC18B11.05", "map_id": "SPAC18B11.05", "name": "gpi18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739496", "map_id": "none", "name": "Addition of a second glucose to the N-glycan precursor by ALG8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_449638", "map_id": "CHEBI:53020", "name": "(Glc)2 (GlcNAc)2 (Man)9 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10739493", "map_id": "Q10479", "name": "alg8", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC17C9.07", "map_id": "SPAC17C9.07", "name": "alg8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739692", "map_id": "none", "name": "Acetylation of glucosamine 6-phosphate to GlcNAc6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_449701", "map_id": "CHEBI:15873", "name": "GlcN6P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_449703", "map_id": "CHEBI:15784", "name": "AcGlcN6P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739689", "map_id": "none", "name": "2xGNPNAT1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O13738", "map_id": "O13738", "name": "gna1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC16E8.03", "map_id": "SPAC16E8.03", "name": "gna1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734739", "map_id": "none", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734735", "map_id": "O14460", "name": "eft201", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734737", "map_id": "none", "name": "eEF2:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10734850", "map_id": "none", "name": "(ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8855660", "map_id": "CHEBI:77364", "name": "(ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10734847", "map_id": "none", "name": "PIGF:PIGG", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q09782", "map_id": "Q09782", "name": "las21", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13G6.03", "map_id": "SPAC13G6.03", "name": "las21", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9Y7P2", "map_id": "Q9Y7P2", "name": "PIGF", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1450.15", "map_id": "SPCC1450.15", "name": "PIGF", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755240", "map_id": "none", "name": "RGGT:CHM binds RABs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10755236", "map_id": "none", "name": "RABs:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755140", "map_id": "none", "name": "RABGGTA:RABGGTB:CHMs:GGPP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94412", "map_id": "O94412", "name": "bet4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1620.05", "map_id": "SPCC1620.05", "name": "bet4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_1131164", "map_id": "CHEBI:48861", "name": "geranylgeranyl diphosphate", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none", "complex": "false" }, { "id": "P46960", "map_id": "P46960", "name": "ptb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC167.02", "map_id": "SPAC167.02", "name": "ptb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10755238", "map_id": "none", "name": "RGGT:CHMs:RABs:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10755404", "map_id": "none", "name": "RGGT geranylgeranylates RAB proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10755401", "map_id": "none", "name": "RGGTA:RGGTB:GGPP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755399", "map_id": "none", "name": "CHMs:GGC-RABs:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10755807", "map_id": "none", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10755799", "map_id": "none", "name": "Homologues of Me3K318-EEF1A1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755804", "map_id": "Q9P7Z3", "name": "see1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC839.14c", "map_id": "SPBC839.14c", "name": "see1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739597", "map_id": "none", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_10739592", "map_id": "Q9P7Q9", "name": "alg9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC1834.05", "map_id": "SPAC1834.05", "name": "alg9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734683", "map_id": "none", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734679", "map_id": "none", "name": "Homologues of p-RPL13A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10734681", "map_id": "none", "name": "phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10739605", "map_id": "none", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449293", "map_id": "CHEBI:18341", "name": "N,N'-DCDOLDP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_449283", "map_id": "CHEBI:18396", "name": "MDCDD", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10739602", "map_id": "O13933", "name": "alg1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC23C4.14", "map_id": "SPAC23C4.14", "name": "alg1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739504", "map_id": "none", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449222", "map_id": "CHEBI:18278", "name": "GlcNAcDOLDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10739501", "map_id": "P42881", "name": "gpt2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC15D4.04", "map_id": "SPBC15D4.04", "name": "gpt2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739556", "map_id": "none", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_532204", "map_id": "CHEBI:7125", "name": "AcGlcN1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739553", "map_id": "none", "name": "2xUAP1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94617", "map_id": "O94617", "name": "uap1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1289.08", "map_id": "SPBC1289.08", "name": "uap1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739571", "map_id": "none", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10739568", "map_id": "none", "name": "ALG13:ALG14", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O14190", "map_id": "O14190", "name": "alg13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC56E4.02c", "map_id": "SPAC56E4.02c", "name": "alg13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14199", "map_id": "O14199", "name": "alg14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC5D6.06c", "map_id": "SPAC5D6.06c", "name": "alg14", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755142", "map_id": "none", "name": "RGGT binds the RAB-binding subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10755132", "map_id": "none", "name": "RABGGTA:RABGGTB", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755138", "map_id": "none", "name": "CHMs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10734858", "map_id": "none", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8855664", "map_id": "none", "name": "mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_453088", "compartment_display": "integral component of lumenal side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10734855", "map_id": "Q09837", "name": "smp3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC4G8.12c", "map_id": "SPAC4G8.12c", "name": "smp3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744931", "map_id": "none", "name": "RANBP2 SUMOylates HDAC4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744921", "map_id": "P56523", "name": "clr3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744929", "map_id": "none", "name": "SUMO1:HDAC4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10739538", "map_id": "none", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_532531", "map_id": "CHEBI:35374", "name": "Man1P", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739533", "map_id": "Q9UTJ2", "name": "pmm1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC1556.07", "map_id": "SPAC1556.07", "name": "pmm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744981", "map_id": "none", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10729457", "map_id": "Q03392", "name": "pcn1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744979", "map_id": "none", "name": "SUMO1:PCNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10744729", "map_id": "none", "name": "SUMOylation of ING2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744727", "map_id": "none", "name": "SUMO1:ING2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10748783", "map_id": "none", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10748776", "map_id": "none", "name": "USP3,SAGA:Ub-histone H2A, Ub-histone H2B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O74443", "map_id": "O74443", "name": "laf2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1682.13", "map_id": "SPCC1682.13", "name": "laf2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7J7", "map_id": "Q9P7J7", "name": "ada2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC24B10.08c", "map_id": "SPCC24B10.08c", "name": "ada2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13719", "map_id": "O13719", "name": "laf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC14C4.12c", "map_id": "SPAC14C4.12c", "name": "laf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUK2", "map_id": "Q9UUK2", "name": "gcn5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1952.05", "map_id": "SPAC1952.05", "name": "gcn5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUD6", "map_id": "Q9UUD6", "name": "ubp11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19C2.04c", "map_id": "SPBC19C2.04c", "name": "ubp11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USU8", "map_id": "Q9USU8", "name": "ngg1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC28F2.10c", "map_id": "SPBC28F2.10c", "name": "ngg1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10748780", "map_id": "none", "name": "USP3,SAGA:Histone H2A,Histone H2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747105", "map_id": "none", "name": "PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5687536", "map_id": "CHEBI:85309", "name": "isoAsp", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5687529", "map_id": "CHEBI:31882", "name": "MetAsp", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10747102", "map_id": "Q9URZ1", "name": "pcm2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC869.08", "map_id": "SPAC869.08", "name": "pcm2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745717", "map_id": "none", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10745709", "map_id": "O14460", "name": "eft201", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745714", "map_id": "O74898", "name": "dph5", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC576.14", "map_id": "SPCC576.14", "name": "dph5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10749267", "map_id": "none", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10749262", "map_id": "none", "name": "USP5:PolyUb", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q11119", "map_id": "Q11119", "name": "ubp14", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749264", "map_id": "none", "name": "USP5:Ub", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10734729", "map_id": "none", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734724", "map_id": "none", "name": "eEF1A:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10734706", "map_id": "none", "name": "eEF1A:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10734726", "map_id": "none", "name": "eEF1B:GDP exchange complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10745703", "map_id": "none", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10745695", "map_id": "O14460", "name": "eft201", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10745700", "map_id": "Q9USQ7", "name": "mug71", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC577.12", "map_id": "SPBC577.12", "name": "mug71", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744614", "map_id": "none", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10744604", "map_id": "P24782", "name": "dbp2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744612", "map_id": "none", "name": "SUMO1:DDX17", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734687", "map_id": "none", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734685", "map_id": "none", "name": "60s ribosomal complex lacking L13a subunit", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10731937", "map_id": "none", "name": "Homologues of RPL13A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10750104", "map_id": "none", "name": "USP13 deubiquitinates BECN1,USP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10750099", "map_id": "none", "name": "USP13:K63polyUb-BECN1,K63polyUb-USP10", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10750101", "map_id": "none", "name": "USP13:BECN1,USP10", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10734783", "map_id": "none", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_8855666", "map_id": "CHEBI:52572", "name": "glucosaminyl-acyl-PI", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10734780", "map_id": "Q9UTL4", "name": "gwt1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC144.10c", "map_id": "SPAC144.10c", "name": "gwt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744969", "map_id": "none", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10741535", "map_id": "O59702", "name": "clr6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744967", "map_id": "none", "name": "2SUMO1:HDAC1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747799", "map_id": "none", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10747795", "map_id": "Q92353", "name": "ubp6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC6G9.08", "map_id": "SPAC6G9.08", "name": "ubp6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747797", "map_id": "none", "name": "ADRM1:26S proteasome:USP14", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q92353", "map_id": "Q92353", "name": "ubp6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745017", "map_id": "none", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745008", "map_id": "P08096", "name": "top2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10745015", "map_id": "none", "name": "SUMO1:TOP2B", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10749279", "map_id": "none", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10749274", "map_id": "none", "name": "USP16,USP21:Ub-histone H2A", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9P7S5", "map_id": "Q9P7S5", "name": "ubp7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10749276", "map_id": "none", "name": "USP16,USP22:Histone H2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10755134", "map_id": "none", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10755130", "map_id": "P46960", "name": "ptb1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10755128", "map_id": "O94412", "name": "bet4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10739595", "map_id": "none", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "reaction_10755762", "map_id": "none", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10731070", "map_id": "Q10265", "name": "ssa1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10755754", "map_id": "Q10265", "name": "ssa1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10755759", "map_id": "O13926", "name": "METTL21A", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10739579", "map_id": "none", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_449737", "map_id": "CHEBI:59085", "name": "(GlcNAc)2 (Man)2 (PP-Dol)1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_453087", "compartment_display": "integral component of cytoplasmic side of endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10739576", "map_id": "Q96WW6", "name": "alg2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC11B10.01", "map_id": "SPBC11B10.01", "name": "alg2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739682", "map_id": "none", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739679", "map_id": "none", "name": "GFPT1,2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09740", "map_id": "Q09740", "name": "GFPT2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC12C2.11", "map_id": "SPBC12C2.11", "name": "GFPT2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10744836", "map_id": "none", "name": "RANBP2 SUMOylates RANBP2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10744823", "map_id": "Q09717", "name": "sbp1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "false" }, { "id": "species_10744833", "map_id": "none", "name": "3SUMO1:RANBP2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_13231", "compartment_display": "nuclear envelope", "complex": "true" }, { "id": "reaction_10739480", "map_id": "none", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739477", "map_id": "Q09687", "name": "PGM3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC13C5.05c", "map_id": "SPAC13C5.05c", "name": "PGM3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10738916", "map_id": "none", "name": "Endonucleolytic RISC hydrolyzes target RNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_426523", "map_id": "none", "name": "RNA (exact match)", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_426511", "map_id": "none", "name": "Cleaved RNA with 5' Phosphate and 3' Hydroxyl", "type": "product", "sub_type": "", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10738891", "map_id": "none", "name": "Endonucleolytic RISC", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74957", "map_id": "O74957", "name": "ago1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC736.11", "map_id": "SPCC736.11", "name": "ago1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745975", "map_id": "none", "name": "Importin-8 imports AGO2:miRNA into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10745948", "map_id": "none", "name": "IPO8:AGO2:miRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O59809", "map_id": "O59809", "name": "IPO8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC550.11", "map_id": "SPCC550.11", "name": "IPO8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745956", "map_id": "none", "name": "AGO2:miRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10745972", "map_id": "none", "name": "IPO8:RAN:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745966", "map_id": "none", "name": "AGO1,2:small RNA complexes interact with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745962", "map_id": "none", "name": "AGO1,2:miRNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10745964", "map_id": "none", "name": "AGO1,2:miRNA:chromatin:RNA pol II", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10757019", "map_id": "none", "name": "C3PO hydrolyzes cleaved passenger strand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757004", "map_id": "none", "name": "AGO2:cleaved duplex siRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10738889", "map_id": "none", "name": "AGO2:siRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757016", "map_id": "none", "name": "C3PO", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74955", "map_id": "O74955", "name": "TSNAX", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC736.09c", "map_id": "SPCC736.09c", "name": "TSNAX", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P7V3", "map_id": "Q9P7V3", "name": "tsn1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC30.03c", "map_id": "SPAC30.03c", "name": "tsn1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10745950", "map_id": "none", "name": "Importin-8 binds AGO2:miRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738887", "map_id": "none", "name": "AGO2:miRNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10745946", "map_id": "O59809", "name": "IPO8", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10757024", "map_id": "none", "name": "AGO2 cleaves passenger strand of duplex siRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757021", "map_id": "none", "name": "AGO2:duplex siRNA", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10732342", "map_id": "none", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500829", "map_id": "none", "name": "Cyt-Rib, dC", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:17562", "map_id": "CHEBI:17562", "name": "CHEBI:17562", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:15698", "map_id": "CHEBI:15698", "name": "CHEBI:15698", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_500430", "map_id": "none", "name": "(d)Ura", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:16704", "map_id": "CHEBI:16704", "name": "CHEBI:16704", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:16450", "map_id": "CHEBI:16450", "name": "CHEBI:16450", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10732339", "map_id": "none", "name": "CDA tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756398", "map_id": "none", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_500759", "map_id": "none", "name": "Cyt-Rib, Ura-Rib", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_500761", "map_id": "none", "name": "CMP, UMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10756395", "map_id": "O74427", "name": "urk1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC162.11c", "map_id": "SPCC162.11c", "name": "urk1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10750462", "map_id": "none", "name": "HDHD1:Mg2+ dephosphorylates PURIDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6788291", "map_id": "CHEBI:18116", "name": "PURIDP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6788290", "map_id": "CHEBI:17802", "name": "PURID", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10750459", "map_id": "none", "name": "HDHD1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O59760", "map_id": "O59760", "name": "HDHD1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1020.07", "map_id": "SPCC1020.07", "name": "HDHD1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736241", "map_id": "none", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196344", "map_id": "CHEBI:63837", "name": "pregn-5-ene-3,20-dione", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193055", "map_id": "CHEBI:17026", "name": "P4", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736238", "map_id": "none", "name": "HSD2B1 dimer, HSD3B2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O43050", "map_id": "O43050", "name": "erg26", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736360", "map_id": "none", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193103", "map_id": "CHEBI:16581", "name": "PREG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10746449", "map_id": "none", "name": "SORD oxidizes D-sorbitol to Fru", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5652213", "map_id": "CHEBI:17924", "name": "D-sorbitol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29532", "map_id": "CHEBI:15824", "name": "Fru", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10746437", "map_id": "none", "name": "AKR1B1 reduces Glc to D-sorbitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10729667", "map_id": "none", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30393", "map_id": "CHEBI:17378", "name": "GA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729664", "map_id": "none", "name": "TKFC:2Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74215", "map_id": "O74215", "name": "dak2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC977.16c", "map_id": "SPAC977.16c", "name": "dak2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10753479", "map_id": "none", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6799497", "map_id": "CHEBI:32398", "name": "DGA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10745910", "map_id": "none", "name": "PHF8 demethylates MeK21-histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743010", "map_id": "P09322", "name": "hhf3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10743019", "map_id": "O94603", "name": "jhd1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10755942", "map_id": "none", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733280", "map_id": "P04551", "name": "cdc2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10755938", "map_id": "none", "name": "Cyclin D", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10755940", "map_id": "none", "name": "CDK4,CDK6:CCND", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10758108", "map_id": "none", "name": "CDK6 inhibitors bind CDK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_9754132", "map_id": "none", "name": "CDK6 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=10426", "map_id": "LigandDisplayForward?ligandId=10426", "name": "LigandDisplayForward?ligandId=10426", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=9923", "map_id": "LigandDisplayForward?ligandId=9923", "name": "LigandDisplayForward?ligandId=9923", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=9626", "map_id": "LigandDisplayForward?ligandId=9626", "name": "LigandDisplayForward?ligandId=9626", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=11189", "map_id": "LigandDisplayForward?ligandId=11189", "name": "LigandDisplayForward?ligandId=11189", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7383", "map_id": "LigandDisplayForward?ligandId=7383", "name": "LigandDisplayForward?ligandId=7383", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7382", "map_id": "LigandDisplayForward?ligandId=7382", "name": "LigandDisplayForward?ligandId=7382", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7380", "map_id": "LigandDisplayForward?ligandId=7380", "name": "LigandDisplayForward?ligandId=7380", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=5969", "map_id": "LigandDisplayForward?ligandId=5969", "name": "LigandDisplayForward?ligandId=5969", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7934", "map_id": "LigandDisplayForward?ligandId=7934", "name": "LigandDisplayForward?ligandId=7934", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=10313", "map_id": "LigandDisplayForward?ligandId=10313", "name": "LigandDisplayForward?ligandId=10313", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7379", "map_id": "LigandDisplayForward?ligandId=7379", "name": "LigandDisplayForward?ligandId=7379", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10756021", "map_id": "none", "name": "p-T177-CDK6:CCND", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10758106", "map_id": "none", "name": "p-T177-CDK6:CCND:CDK6 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756036", "map_id": "none", "name": "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10756008", "map_id": "none", "name": "CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10756034", "map_id": "none", "name": "p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10758118", "map_id": "none", "name": "CDK4 inhibitors bind CDK4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10756032", "map_id": "none", "name": "p-T172-CDK4:CCND", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_9754127", "map_id": "none", "name": "CDK4 inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=7938", "map_id": "LigandDisplayForward?ligandId=7938", "name": "LigandDisplayForward?ligandId=7938", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=5950", "map_id": "LigandDisplayForward?ligandId=5950", "name": "LigandDisplayForward?ligandId=5950", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=5707", "map_id": "LigandDisplayForward?ligandId=5707", "name": "LigandDisplayForward?ligandId=5707", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=7744", "map_id": "LigandDisplayForward?ligandId=7744", "name": "LigandDisplayForward?ligandId=7744", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "pubchem.compound:9933545", "map_id": "pubchem.compound:9933545", "name": "pubchem.compound:9933545", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=8203", "map_id": "LigandDisplayForward?ligandId=8203", "name": "LigandDisplayForward?ligandId=8203", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=5680", "map_id": "LigandDisplayForward?ligandId=5680", "name": "LigandDisplayForward?ligandId=5680", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10758116", "map_id": "none", "name": "p-T172-CDK4:CCND:CDK4 inhibitors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756010", "map_id": "none", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_13231", "compartment_display": "nuclear envelope" }, { "id": "species_10755982", "map_id": "none", "name": "CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B)", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10733308", "map_id": "none", "name": "Transport of Citrate from Mitochondrial Matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_198498", "map_id": "CHEBI:30797", "name": "MAL", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10733300", "map_id": "none", "name": "ACLY tetramer transforms CIT to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733297", "map_id": "none", "name": "ACLY tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10736846", "map_id": "none", "name": "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10733319", "map_id": "P78820", "name": "cut6", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10752466", "map_id": "none", "name": "CHM binds RGGT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10752455", "map_id": "none", "name": "RGGT", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10752462", "map_id": "O60112", "name": "CHM", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10752464", "map_id": "none", "name": "RGGT:CHM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10752457", "map_id": "none", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10752448", "map_id": "O94412", "name": "bet4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10752453", "map_id": "P46960", "name": "ptb1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10746376", "map_id": "none", "name": "SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746366", "map_id": "P09322", "name": "hhf3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10746371", "map_id": "Q9USK2", "name": "set9", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPCC4B3.12", "map_id": "SPCC4B3.12", "name": "set9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746381", "map_id": "none", "name": "SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746379", "map_id": "P09322", "name": "hhf3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10745162", "map_id": "none", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745159", "map_id": "P09322", "name": "hhf3", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10743825", "map_id": "Q9URX7", "name": "rmt1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPAC890.07c", "map_id": "SPAC890.07c", "name": "rmt1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746660", "map_id": "none", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10746658", "map_id": "P09322", "name": "hhf3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10743853", "map_id": "none", "name": "CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10743844", "map_id": "none", "name": "CCND1:CDK4:PRMT5:WDR77", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P78963", "map_id": "P78963", "name": "skb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC16H5.11c", "map_id": "SPBC16H5.11c", "name": "skb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743850", "map_id": "none", "name": "CCND1:CDK4:PRMT5:pT5-WDR77", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10745307", "map_id": "none", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745271", "map_id": "none", "name": "MeR12-histone H2A, Histone H2A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10745305", "map_id": "none", "name": "Me2aR12-histone H2A, MeR12-histone H2A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10737810", "map_id": "none", "name": "Antizyme inhibitor binds to OAZ and stablizes ODC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737804", "map_id": "Q9UQW9", "name": "spe1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737795", "map_id": "none", "name": "ODC:OAZ complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UQW9", "map_id": "Q9UQW9", "name": "spe1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USQ5", "map_id": "Q9USQ5", "name": "spa1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC577.14c", "map_id": "SPBC577.14c", "name": "spa1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10737808", "map_id": "none", "name": "AZIN1 bound OAZ:ODC complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10737980", "map_id": "none", "name": "26S proteosome degrades ODC holoenzyme complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737789", "map_id": "Q9USQ5", "name": "spa1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10737797", "map_id": "none", "name": "Antizyme OAZ binds to Ornithine decarboxylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10730038", "map_id": "Q9UQW9", "name": "spe1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10752439", "map_id": "none", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10752434", "map_id": "P14605", "name": "cyr1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC19C7.03", "map_id": "SPBC19C7.03", "name": "phospho-cyr1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10752437", "map_id": "P14605", "name": "phospho-cyr1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10752490", "map_id": "none", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10752485", "map_id": "none", "name": "TRIAP1:PRELID1, PRELID3A", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "Q96VG1", "map_id": "Q96VG1", "name": "TRIAP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC119.18", "map_id": "SPBC119.18", "name": "TRIAP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O59707", "map_id": "O59707", "name": "PRELID3A", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC36.10", "map_id": "SPBC36.10", "name": "PRELID3A", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UT07", "map_id": "Q9UT07", "name": "PRELID1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAP8A3.10", "map_id": "SPAP8A3.10", "name": "PRELID1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10752443", "map_id": "none", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10752441", "map_id": "P14605", "name": "phospho-cyr1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10752487", "map_id": "none", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space" }, { "id": "species_10752471", "map_id": "Q96VG1", "name": "TRIAP1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "false" }, { "id": "species_10752483", "map_id": "none", "name": "PRELID1, PRELID3A", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17927", "compartment_display": "mitochondrial intermembrane space", "complex": "true" }, { "id": "reaction_10746130", "map_id": "none", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746127", "map_id": "none", "name": "acetylated microtubule", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10745603", "map_id": "P56523", "name": "clr3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10743065", "map_id": "none", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_20699", "compartment_display": "Golgi membrane" }, { "id": "species_10743057", "map_id": "none", "name": "p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "P50528", "map_id": "P50528", "name": "phospho-plo1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10743062", "map_id": "none", "name": "p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10757878", "map_id": "none", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10756754", "map_id": "none", "name": "Homologues of PAK5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757872", "map_id": "none", "name": "RHOD:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "species_10757876", "map_id": "none", "name": "RHOD:GTP:RHOD mitochondrial outer membrane effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10746782", "map_id": "none", "name": "PAK2 phosphorylates myosin regulatory light chain (MRLC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746773", "map_id": "none", "name": "Smooth muscle/non-muscle myosin II", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9USI6", "map_id": "Q9USI6", "name": "myo2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC645.05c", "map_id": "SPCC645.05c", "name": "myo2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09196", "map_id": "Q09196", "name": "cdc4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAP8A3.08", "map_id": "SPAP8A3.08", "name": "cdc4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UUG5", "map_id": "Q9UUG5", "name": "phospho-rlc1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC926.03", "map_id": "SPAC926.03", "name": "phospho-rlc1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O14157", "map_id": "O14157", "name": "myo3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4A8.05c", "map_id": "SPAC4A8.05c", "name": "myo3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10746779", "map_id": "none", "name": "p-T19-MRLC-Smooth muscle/non-muscle myosin II", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746316", "map_id": "none", "name": "Homologues of p-S141,T402-PAK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10756841", "map_id": "none", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756831", "map_id": "none", "name": "RHOD:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10756817", "map_id": "none", "name": "RHOD:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757894", "map_id": "none", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10757892", "map_id": "none", "name": "RHOD:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_20699", "compartment_display": "Golgi membrane", "complex": "true" }, { "id": "reaction_10756608", "map_id": "none", "name": "TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10732432", "map_id": "P17871", "name": "tbp1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10756604", "map_id": "none", "name": "ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "CHEBI:142773", "map_id": "CHEBI:142773", "name": "CHEBI:142773", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94720", "map_id": "O94720", "name": "fil1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1393.08", "map_id": "SPCC1393.08", "name": "fil1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_193132", "map_id": "CHEBI:16469", "name": "EST17b", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "Q10280", "map_id": "Q10280", "name": "gaf1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1902.01", "map_id": "SPCC1902.01", "name": "gaf1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10134", "map_id": "Q10134", "name": "fep1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23E2.01", "map_id": "SPAC23E2.01", "name": "fep1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:27974", "map_id": "CHEBI:27974", "name": "CHEBI:27974", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_193066", "map_id": "CHEBI:17263", "name": "E1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10756606", "map_id": "none", "name": "TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756525", "map_id": "none", "name": "RAC1 and CDC42 activate PAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738343", "map_id": "none", "name": "PAK2 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746302", "map_id": "none", "name": "CDC42:GTP,RAC1:GTP:PAK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10738341", "map_id": "none", "name": "Homologues of PAK2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746286", "map_id": "none", "name": "GTP-bound RAC1 and CDC42 bind IQGAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10746282", "map_id": "none", "name": "IQGAP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746284", "map_id": "none", "name": "RAC1,CDC42:GTP:IQGAPs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10757002", "map_id": "none", "name": "PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10756994", "map_id": "none", "name": "ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9URX7", "map_id": "Q9URX7", "name": "rmt1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746295", "map_id": "none", "name": "IQGAPs bind CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10737009", "map_id": "none", "name": "CALM1:4Ca2+", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10746290", "map_id": "none", "name": "RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10756782", "map_id": "none", "name": "CDC42 GDIs block activation of CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756776", "map_id": "none", "name": "CDC42:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10756778", "map_id": "none", "name": "CDC42 GDIs", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10756780", "map_id": "none", "name": "CDC42:GDP:CDC42 GDIs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10758013", "map_id": "none", "name": "Phosphorylated RHOU translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10758007", "map_id": "none", "name": "p-Y254-RHOU:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10758011", "map_id": "none", "name": "p-Y254-RHOU:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10756867", "map_id": "none", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756855", "map_id": "none", "name": "RHOD:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "species_10756863", "map_id": "none", "name": "RHOD endosome effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10756865", "map_id": "none", "name": "RHOD:GTP:RHOD endosome effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "reaction_10757000", "map_id": "none", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10756996", "map_id": "none", "name": "ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10756988", "map_id": "none", "name": "histone acetyltransferases", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10756998", "map_id": "none", "name": "ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756484", "map_id": "none", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10734490", "map_id": "none", "name": "RHOA:GDP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10734492", "map_id": "none", "name": "RHOA:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10738645", "map_id": "none", "name": "Homologues of RASGRF2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746292", "map_id": "none", "name": "IQGAPs bind F-actin, which is inhibited by calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10742720", "map_id": "none", "name": "F-actin", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746288", "map_id": "none", "name": "RAC1,CDC42:GTP:IQGAP:F-actin", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10756869", "map_id": "none", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10756701", "map_id": "none", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756697", "map_id": "none", "name": "RHOA plasma membrane effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10756699", "map_id": "none", "name": "RHOA:GTP:cytosolic RHOA effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10757843", "map_id": "none", "name": "CDC42 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10757841", "map_id": "none", "name": "CDC42:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10756625", "map_id": "none", "name": "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10756620", "map_id": "none", "name": "KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "CHEBI:50114", "map_id": "CHEBI:50114", "name": "CHEBI:50114", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10747338", "map_id": "O94691", "name": "jmj3", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10756622", "map_id": "none", "name": "KDM4B-regulated genes:nucleosome:ESR1:ESTG", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756686", "map_id": "none", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756684", "map_id": "none", "name": "RHOA:GTP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10756523", "map_id": "none", "name": "RAC1 and CDC42 activate PAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10738347", "map_id": "none", "name": "PAK3 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746304", "map_id": "none", "name": "CDC42:GTP,RAC1:GTP:PAK3", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10738345", "map_id": "P50527", "name": "shk1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10756658", "map_id": "none", "name": "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10756653", "map_id": "none", "name": "MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10756655", "map_id": "none", "name": "MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10756519", "map_id": "none", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756516", "map_id": "none", "name": "RHOA GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757377", "map_id": "none", "name": "PIN1 binds p-S345-NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757370", "map_id": "none", "name": "p-S-345-NCF1:NCF2:NCF4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O42854", "map_id": "O42854", "name": "NCF2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC23A1.17", "map_id": "SPAC23A1.17", "name": "NCF2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757372", "map_id": "O74448", "name": "pin1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10757374", "map_id": "none", "name": "PIN1:p-S-345-NCF1:NCF2:NCF4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10746044", "map_id": "none", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5263232", "compartment_display": "ciliary base" }, { "id": "species_10746040", "map_id": "none", "name": "PKA tetramer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "species_10746034", "map_id": "P40376", "name": "pka1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "false" }, { "id": "species_10746042", "map_id": "none", "name": "PKA regulatory subunits:cAMP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5263232", "compartment_display": "ciliary base", "complex": "true" }, { "id": "reaction_10756834", "map_id": "none", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10756918", "map_id": "none", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756915", "map_id": "none", "name": "RHOU:GDP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "species_10756895", "map_id": "none", "name": "RHOU:GTP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10756793", "map_id": "none", "name": "CDC42 GEFs activate CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756790", "map_id": "none", "name": "CDC42 GEFs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10745852", "map_id": "none", "name": "SYVN1 ubiquitinates Hh C-terminal fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10745845", "map_id": "none", "name": "C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O13875", "map_id": "O13875", "name": "SEL1L", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1B3.10c", "map_id": "SPAC1B3.10c", "name": "SEL1L", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9UTC8", "map_id": "Q9UTC8", "name": "yos9", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC227.11c", "map_id": "SPAC227.11c", "name": "yos9", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74757", "map_id": "O74757", "name": "hrd1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC17D11.02c", "map_id": "SPBC17D11.02c", "name": "hrd1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94458", "map_id": "O94458", "name": "DERL2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1687.17c", "map_id": "SPAC1687.17c", "name": "DERL2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10745849", "map_id": "none", "name": "ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10756682", "map_id": "none", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756678", "map_id": "none", "name": "ARHGDIA,ARHGDIB", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10756680", "map_id": "none", "name": "RHOA GDIs:RHOA:GDP", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757858", "map_id": "none", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757854", "map_id": "none", "name": "RHOD plasma membrane effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9HGP5", "map_id": "Q9HGP5", "name": "acp2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC631.01c", "map_id": "SPAC631.01c", "name": "acp2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q7LKY2", "map_id": "Q7LKY2", "name": "ADD3(2-706)", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1289.14", "map_id": "SPBC1289.14", "name": "ADD3(2-706)", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10757856", "map_id": "none", "name": "RHOD:GTP:RHOD plasma membrane effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10751276", "map_id": "none", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane" }, { "id": "species_1524165", "map_id": "CHEBI:16749", "name": "PI", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10751273", "map_id": "none", "name": "PIK3C3:PIK3R4", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_1222693", "compartment_display": "phagocytic vesicle membrane", "complex": "true" }, { "id": "reaction_10756913", "map_id": "none", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756909", "map_id": "none", "name": "RHOU effectors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10756911", "map_id": "none", "name": "RHOU:GTP:RHOU effectors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10757398", "map_id": "none", "name": "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757392", "map_id": "none", "name": "NCF1:NCF2:NCF4", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10739926", "map_id": "Q09892", "name": "phospho-sty1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10756800", "map_id": "none", "name": "CDC42 GAPs stimulate CDC42 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_10756797", "map_id": "none", "name": "CDC42 GAPs", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757395", "map_id": "none", "name": "MAPK1 or MAPK3 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10757874", "map_id": "none", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "reaction_10757388", "map_id": "none", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757386", "map_id": "none", "name": "PIN1:p-S-6S-NCF1:NCF2:NCF4", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10749638", "map_id": "none", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_428256", "map_id": "CHEBI:17761", "name": "CERA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_5693768", "map_id": "CHEBI:85781", "name": "2HCERA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10749635", "map_id": "O13846", "name": "scs7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPAC19G12.08", "map_id": "SPAC19G12.08", "name": "scs7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739067", "map_id": "none", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428275", "map_id": "CHEBI:16893", "name": "SPAP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428694", "map_id": "CHEBI:16566", "name": "SPA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10739064", "map_id": "none", "name": "SGPP", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9P6N5", "map_id": "Q9P6N5", "name": "SGPP1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC823.11", "map_id": "SPAC823.11", "name": "SGPP1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739084", "map_id": "none", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428203", "map_id": "CHEBI:37550", "name": "S1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_428682", "map_id": "CHEBI:16393", "name": "SPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10739049", "map_id": "none", "name": "dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428206", "map_id": "none", "name": "NAD(P)H", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_428126", "map_id": "CHEBI:31488", "name": "DHCE", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_428218", "map_id": "none", "name": "NAD(P)+", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10739046", "map_id": "O59715", "name": "dsd1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10739027", "map_id": "none", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428163", "map_id": "CHEBI:16566", "name": "SPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10739024", "map_id": "none", "name": "LASS proteins", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O59735", "map_id": "O59735", "name": "lac1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3E7.15c", "map_id": "SPBC3E7.15c", "name": "lac1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78970", "map_id": "P78970", "name": "lag1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1A6.09c", "map_id": "SPAC1A6.09c", "name": "lag1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739055", "map_id": "none", "name": "SPHK1 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_428193", "map_id": "CHEBI:16393", "name": "SPG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10739041", "map_id": "none", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739038", "map_id": "none", "name": "SPHK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10739052", "map_id": "none", "name": "dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9025544", "map_id": "CHEBI:31998", "name": "N-acylphytosphingosine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10757901", "map_id": "none", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739036", "map_id": "none", "name": "Homologues of SPHK2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10757899", "map_id": "none", "name": "SPHK2:SPHK2 inhibitors", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=6625", "map_id": "LigandDisplayForward?ligandId=6625", "name": "LigandDisplayForward?ligandId=6625", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=10641", "map_id": "LigandDisplayForward?ligandId=10641", "name": "LigandDisplayForward?ligandId=10641", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=10219", "map_id": "LigandDisplayForward?ligandId=10219", "name": "LigandDisplayForward?ligandId=10219", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=6624", "map_id": "LigandDisplayForward?ligandId=6624", "name": "LigandDisplayForward?ligandId=6624", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10739081", "map_id": "none", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10739072", "map_id": "Q9UUA6", "name": "dpp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10739075", "map_id": "none", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_984", "compartment_display": "extracellular region" }, { "id": "species_419305", "map_id": "CHEBI:37550", "name": "S1P", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "species_428662", "map_id": "CHEBI:16393", "name": "SPG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_984", "compartment_display": "extracellular region", "complex": "false" }, { "id": "reaction_10740345", "map_id": "none", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740341", "map_id": "Q9HGP5", "name": "acp2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740336", "map_id": "Q10434", "name": "acp1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC12B10.07", "map_id": "SPAC12B10.07", "name": "acp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10740343", "map_id": "none", "name": "F-actin capping protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10434", "map_id": "Q10434", "name": "acp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741463", "map_id": "none", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10741456", "map_id": "P40381", "name": "swi6", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10741459", "map_id": "P09988", "name": "hht1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10741461", "map_id": "none", "name": "HP1alpha:Histone H3 methylated at K9", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10741481", "map_id": "none", "name": "EHD proteins interact with Rabenosyn-5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_74700", "compartment_display": "endosome membrane" }, { "id": "species_10741477", "map_id": "O13786", "name": "pep7", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "false" }, { "id": "SPAC17G6.08", "map_id": "SPAC17G6.08", "name": "pep7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741468", "map_id": "O13736", "name": "sla1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "false" }, { "id": "SPAC16E8.01", "map_id": "SPAC16E8.01", "name": "sla1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741479", "map_id": "none", "name": "C-terminal EH domain containing proteins:Rabenosyn-5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_74700", "compartment_display": "endosome membrane", "complex": "true" }, { "id": "O13786", "map_id": "O13786", "name": "pep7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O13736", "map_id": "O13736", "name": "sla1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741454", "map_id": "none", "name": "Dual-specific AKAPs bind type I and II PKA regulatory subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741450", "map_id": "Q9P7S8", "name": "rax1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC23G3.05c", "map_id": "SPAC23G3.05c", "name": "rax1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10741452", "map_id": "none", "name": "Dual-specific AKAPs:PKA tetramer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P7S8", "map_id": "Q9P7S8", "name": "rax1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741445", "map_id": "none", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane" }, { "id": "species_10741439", "map_id": "Q9USY7", "name": "fzo1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "false" }, { "id": "species_10741443", "map_id": "none", "name": "Mitofusin complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_17906", "compartment_display": "mitochondrial outer membrane", "complex": "true" }, { "id": "reaction_10750893", "map_id": "none", "name": "21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10750858", "map_id": "none", "name": "21S pre-rRNA:SSU processome", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9HDY4", "map_id": "Q9HDY4", "name": "DHX37", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB1A10.06c", "map_id": "SPAPB1A10.06c", "name": "DHX37", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60055", "map_id": "O60055", "name": "utp20", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC56F2.04", "map_id": "SPBC56F2.04", "name": "utp20", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9USN3", "map_id": "Q9USN3", "name": "utp13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC16A11.02", "map_id": "SPCC16A11.02", "name": "utp13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94365", "map_id": "O94365", "name": "utp15", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC428.19c", "map_id": "SPBC428.19c", "name": "utp15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60179", "map_id": "O60179", "name": "utp10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC23E6.04c", "map_id": "SPBC23E6.04c", "name": "utp10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q09775", "map_id": "Q09775", "name": "rok1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC22F3.08c", "map_id": "SPAC22F3.08c", "name": "rok1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60161", "map_id": "O60161", "name": "utp4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19F5.02c", "map_id": "SPBC19F5.02c", "name": "utp4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P6P2", "map_id": "Q9P6P2", "name": "rrp36", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC823.04", "map_id": "SPAC823.04", "name": "rrp36", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P35551", "map_id": "P35551", "name": "fib1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC2D10.10c", "map_id": "SPBC2D10.10c", "name": "fib1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60188", "map_id": "O60188", "name": "utp6", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC244.02c", "map_id": "SPBC244.02c", "name": "utp6", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10107", "map_id": "Q10107", "name": "mra1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC18G6.07c", "map_id": "SPAC18G6.07c", "name": "mra1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74835", "map_id": "O74835", "name": "rrp5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1183.07", "map_id": "SPCC1183.07", "name": "rrp5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9C1X1", "map_id": "Q9C1X1", "name": "PWP2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC713.04c", "map_id": "SPBC713.04c", "name": "PWP2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10106", "map_id": "Q10106", "name": "utp11", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC18G6.06", "map_id": "SPAC18G6.06", "name": "utp11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P78750", "map_id": "P78750", "name": "UTP18", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC29A3.06", "map_id": "SPBC29A3.06", "name": "UTP18", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9P6N8", "map_id": "Q9P6N8", "name": "rrp3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC823.08c", "map_id": "SPAC823.08c", "name": "rrp3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94683", "map_id": "O94683", "name": "rrp7", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC776.17", "map_id": "SPBC776.17", "name": "rrp7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94676", 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Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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"compartment_display": "none" }, { "id": "SPBC16C6.12c", "map_id": "SPBC16C6.12c", "name": "las1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q9URY0", "map_id": "Q9URY0", "name": "ytm1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC890.04c", "map_id": "SPAC890.04c", "name": "ytm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74399", "map_id": "O74399", "name": "erb1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC4F6.13c", "map_id": "SPBC4F6.13c", "name": "erb1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O94718", "map_id": "O94718", "name": "ipi1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1393.06c", "map_id": "SPCC1393.06c", "name": "ipi1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "P87243", "map_id": "P87243", "name": "rix1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC4G3.18", "map_id": "SPCC4G3.18", "name": "rix1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O42957", "map_id": "O42957", "name": "ulp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10272", "map_id": "Q10272", "name": "crb3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC13G7.08c", "map_id": "SPAC13G7.08c", "name": "crb3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O60164", "map_id": "O60164", "name": "ppp1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC19F5.05c", "map_id": "SPBC19F5.05c", "name": "ppp1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750552", "map_id": "none", "name": "28S rRNA:12S pre-rRNA:Rix1:LAS1L:NOL9:SENP3:PeBoW", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10750593", "map_id": "none", "name": "PeBoW complex", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10750543", "map_id": "O42936", "name": "las1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10750609", "map_id": "none", "name": "GNL3:EBNA1BP2:DDX21:PES1", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O13802", "map_id": "O13802", "name": "ebp2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC17H9.05", "map_id": "SPAC17H9.05", "name": "ebp2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "O74791", "map_id": "O74791", "name": "grn1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC26H8.08c", "map_id": "SPBC26H8.08c", "name": "grn1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10750548", "map_id": "Q9UU96", "name": "grc3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10732544", "map_id": "none", "name": "AICAR + 10-Formyl-THF => FAICAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111409", "map_id": "CHEBI:58475", "name": "AICAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_419151", "map_id": "CHEBI:57454", "name": "10-formyl-THF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111427", "map_id": "CHEBI:58467", "name": "FAICAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732538", "map_id": "none", "name": "ATIC dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74928", "map_id": "O74928", "name": "ade10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCPB16A4.03c", "map_id": "SPCPB16A4.03c", "name": "ade10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757804", "map_id": "none", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_9678719", "map_id": "none", "name": "IMPDH inhibitors", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "LigandDisplayForward?ligandId=6832", "map_id": "LigandDisplayForward?ligandId=6832", "name": "LigandDisplayForward?ligandId=6832", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=6845", "map_id": "LigandDisplayForward?ligandId=6845", "name": "LigandDisplayForward?ligandId=6845", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "LigandDisplayForward?ligandId=6842", "map_id": "LigandDisplayForward?ligandId=6842", "name": "LigandDisplayForward?ligandId=6842", "type": "complex_component", "sub_type": "other", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10732528", "map_id": "none", "name": "IMPDH tetramers:IMPDH inhibitors", "type": "inhibitor", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10732518", "map_id": "none", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111584", "map_id": "CHEBI:57464", "name": "XMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732515", "map_id": "Q9P772", "name": "gua1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10732530", "map_id": "none", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10734091", "map_id": "none", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_35141", "map_id": "CHEBI:57567", "name": "ADS", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10734088", "map_id": "none", "name": "ADSS, ADSSL1 dimers", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q02787", "map_id": "Q02787", "name": "ade2", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC144.03", "map_id": "SPAC144.03", "name": "ade2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732576", "map_id": "none", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111292", "map_id": "CHEBI:58681", "name": "PRA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111338", "map_id": "CHEBI:143788", "name": "PRGA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732559", "map_id": "P20772", "name": "ade1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC405.01", "map_id": "SPBC405.01", "name": "ade1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732570", "map_id": "none", "name": "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111354", "map_id": "CHEBI:147286", "name": "N-Formyl-GAR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_111369", "map_id": "CHEBI:147287", "name": "FGAM", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732567", "map_id": "O14228", "name": "ade3", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC6F12.10c", "map_id": "SPAC6F12.10c", "name": "ade3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732573", "map_id": "none", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10732541", "map_id": "none", "name": "FAICAR => IMP + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10732554", "map_id": "none", "name": "SAICAR => AICAR + Fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111399", "map_id": "CHEBI:58443", "name": "SAICAR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_29586", "map_id": "CHEBI:29806", "name": "FUMA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732551", "map_id": "none", "name": "ADSL tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O60105", "map_id": "O60105", "name": "ade8", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC14F5.09c", "map_id": "SPBC14F5.09c", "name": "ade8", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732578", "map_id": "none", "name": "adenylosuccinate => adenosine 5'-monophosphate + fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10732562", "map_id": "none", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_111370", "map_id": "CHEBI:137981", "name": "AIR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10739670", "map_id": "none", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10739644", "map_id": "Q9HGP0", "name": "pvg4", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC317.01", "map_id": "SPBC317.01", "name": "phospho-pvg4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10739654", "map_id": "none", "name": "phospho-p38 alpha/beta/gamma MAPK", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10739667", "map_id": "none", "name": "phospho p38:phospho MEF2", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "Q9HGP0", "map_id": "Q9HGP0", "name": "phospho-pvg4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10754565", "map_id": "none", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10754559", "map_id": "Q9HGM4", "name": "fit1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC543.08", "map_id": "SPBC543.08", "name": "fit1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10754563", "map_id": "none", "name": "(FITM1,FITM2):TAGs", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "Q9HGM4", "map_id": "Q9HGM4", "name": "fit1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10732605", "map_id": "none", "name": "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10744280", "map_id": "none", "name": "SIRT1 binds to HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10738936", "map_id": "O94640", "name": "sir2", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10744242", "map_id": "none", "name": "HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10744244", "map_id": "none", "name": "SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10747248", "map_id": "none", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747243", "map_id": "none", "name": "Shortened telomere:MRN:Ac-K3016-ATM dimer:KAT5", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10747245", "map_id": "none", "name": "Shortened telomere:MRN:KAT5:p-S1981,Ac-K3016-ATM", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10744330", "map_id": "none", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744328", "map_id": "none", "name": "HSP70:ATP", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10744326", "map_id": "none", "name": "HSP40:nascent protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74752", "map_id": "O74752", "name": "mas5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1734.11", "map_id": "SPBC1734.11", "name": "mas5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10744167", "map_id": "none", "name": "HSP40:HSP70:ATP:nascent protein", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10745619", "map_id": "none", "name": "RPA1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10745617", "map_id": "none", "name": "HSF1:RPA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10746067", "map_id": "none", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744276", "map_id": "none", "name": "HSP90:STIP1:HSP70:nascent protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746061", "map_id": "none", "name": "HSP90:ATP:STIP1:HSP70:nascent protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10747237", "map_id": "none", "name": "MRN complex binds shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_3785706", "map_id": "none", "name": "Shortened telomere", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10747220", "map_id": "none", "name": "Shortened telomere:MRN", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10744259", "map_id": "none", "name": "SIRT1 deacetylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10744307", "map_id": "none", "name": "Constitutive phosphorylation by pERK1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744298", "map_id": "none", "name": "Homologues of p-S307-HSF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10744172", "map_id": "none", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744169", "map_id": "none", "name": "HSP40:HSP70:ADP:nascent protein", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10744165", "map_id": "none", "name": "HSP40s", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10744208", "map_id": "none", "name": "Constitutive phosphorylation by GSK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744193", "map_id": "none", "name": "Homologues of p-S303-HSF1", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10744205", "map_id": "none", "name": "Homologues of GSK3B", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9URT9", "map_id": "Q9URT9", "name": "gsk31", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC8D2.01", "map_id": "SPBC8D2.01", "name": "gsk31", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "Q10452", "map_id": "Q10452", "name": "gsk3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1687.15", "map_id": "SPAC1687.15", "name": "gsk3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10747235", "map_id": "none", "name": "MRN complex bound to shortened telomeres recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10747233", "map_id": "none", "name": "Shortened telomere:MRN:ATM dimer:KAT5", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10744278", "map_id": "none", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744264", "map_id": "Q9USI5", "name": "sti1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10738160", "map_id": "none", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10738152", "map_id": "none", "name": "IRE1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "O94537", "map_id": "O94537", "name": "phospho-ire1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC167.01", "map_id": "SPAC167.01", "name": "phospho-ire1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10738157", "map_id": "none", "name": "p-S724-IRE1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10738162", "map_id": "none", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_10738150", "map_id": "O94537", "name": "ire1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "reaction_10751159", "map_id": "none", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10752180", "map_id": "none", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6799540", "map_id": "CHEBI:91284", "name": "alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_429579", "map_id": "CHEBI:4208", "name": "Man", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_6799543", "map_id": "CHEBI:91280", "name": "alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10752177", "map_id": "none", "name": "MAN2C1:Zn2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UT61", "map_id": "Q9UT61", "name": "ams1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC513.05", "map_id": "SPAC513.05", "name": "ams1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757491", "map_id": "none", "name": "PGM1:Mg2+ isomerises G6P to G1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10757486", "map_id": "none", "name": "PGM1:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10729677", "map_id": "none", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29452", "map_id": "CHEBI:18307", "name": "UDP-Gal", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729674", "map_id": "none", "name": "GALE:NAD+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9HDU3", "map_id": "Q9HDU3", "name": "gal10", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBPB2B2.12c", "map_id": "SPBPB2B2.12c", "name": "gal10", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729722", "map_id": "none", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729644", "map_id": "none", "name": "PGM:Mg2+", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10757179", "map_id": "none", "name": "GAA hydrolyzes lysosomal glycogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen" }, { "id": "species_10757148", "map_id": "none", "name": "glycogen-GYG1 dimer", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_1605745", "map_id": "CHEBI:17925", "name": "Glc", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "false" }, { "id": "species_10757158", "map_id": "none", "name": "poly((1,4)-alpha-glucosyl)GYG1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "species_10757176", "map_id": "none", "name": "GAA (70, 76 kDa)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_161320", "compartment_display": "lysosomal lumen", "complex": "true" }, { "id": "reaction_10740698", "map_id": "none", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740694", "map_id": "none", "name": "Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10740696", "map_id": "none", "name": "UPF1:eRF3 Complex on Translated mRNA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10737896", "map_id": "none", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353560", "map_id": "CHEBI:15746", "name": "SPN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_353575", "map_id": "CHEBI:17312", "name": "NASPN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737893", "map_id": "P79081", "name": "ats1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPAC1002.07c", "map_id": "SPAC1002.07c", "name": "ats1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730001", "map_id": "none", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29498", "map_id": "CHEBI:15729", "name": "L-Orn", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_113567", "map_id": "CHEBI:16349", "name": "L-Cit", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10729998", "map_id": "Q10248", "name": "SLC25A15", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70616", "compartment_display": "mitochondrial inner membrane", "complex": "false" }, { "id": "SPAC4G9.20c", "map_id": "SPAC4G9.20c", "name": "SLC25A15", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729981", "map_id": "none", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29642", "map_id": "CHEBI:58048", "name": "L-Asn", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729978", "map_id": "none", "name": "ASNS dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P78753", "map_id": "P78753", "name": "asn1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC119.10", "map_id": "SPBC119.10", "name": "asn1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756871", "map_id": "none", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9013199", "map_id": "CHEBI:18407", "name": "HCN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_9012592", "map_id": "CHEBI:16208", "name": "3MPYR", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_9013191", "map_id": "CHEBI:29200", "name": "HSCN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10756666", "map_id": "Q9USJ1", "name": "tum1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPCC4B3.01", "map_id": "SPCC4B3.01", "name": "tum1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737898", "map_id": "none", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353555", "map_id": "CHEBI:17927", "name": "NASPM", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10757130", "map_id": "none", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10756881", "map_id": "none", "name": "PXLP-K56-SRR dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O59791", "map_id": "O59791", "name": "SRR", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC320.14", "map_id": "SPCC320.14", "name": "SRR", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756803", "map_id": "none", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_1614595", "map_id": "CHEBI:16094", "name": "S2O3(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_9013207", "map_id": "CHEBI:17359", "name": "SO3(2-)", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10741569", "map_id": "none", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1237176", "map_id": "CHEBI:58828", "name": "2,3-DMPP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1237155", "map_id": "CHEBI:58795", "name": "Acireductone", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10741566", "map_id": "none", "name": "E1:Mg++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P6Q2", "map_id": "Q9P6Q2", "name": "utr4", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC644.08", "map_id": "SPAC644.08", "name": "utr4", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729971", "map_id": "none", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "reaction_10740926", "map_id": "none", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_936706", "map_id": "CHEBI:15811", "name": "O-P-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740923", "map_id": "none", "name": "PSPH:Mg2+ dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74382", "map_id": "O74382", "name": "PSPH", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC3H7.07c", "map_id": "SPBC3H7.07c", "name": "PSPH", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742240", "map_id": "none", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614532", "map_id": "CHEBI:16136", "name": "H2S", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742221", "map_id": "none", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614594", "map_id": "CHEBI:62856", "name": "HLAN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10740937", "map_id": "none", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_977329", "map_id": "CHEBI:30933", "name": "3POPA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10740934", "map_id": "none", "name": "PXLP-K200-PSAT1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10349", "map_id": "Q10349", "name": "PXLP-K200-PSAT1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC1F12.07", "map_id": "SPAC1F12.07", "name": "PXLP-K200-PSAT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729901", "map_id": "none", "name": "PXLP-K314-GPT transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729896", "map_id": "none", "name": "PXLP-K314-GPT dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q10334", "map_id": "Q10334", "name": "PXLP-K341-GPT2-1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC582.08", "map_id": "SPBC582.08", "name": "PXLP-K341-GPT2-1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741559", "map_id": "none", "name": "Acireductone is oxidized to MOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1237122", "map_id": "CHEBI:16723", "name": "4MTOBUTA", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10741556", "map_id": "none", "name": "ARD:Fe++", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O94286", "map_id": "O94286", "name": "adi1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC887.01", "map_id": "SPBC887.01", "name": "adi1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10741654", "map_id": "none", "name": "Methylthio-ribulose-P = Methylthio-ribose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1237107", "map_id": "CHEBI:58548", "name": "MTRIBUP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_1237165", "map_id": "CHEBI:58533", "name": "MTRIBP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10741546", "map_id": "O60185", "name": "mri1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC23E6.10c", "map_id": "SPBC23E6.10c", "name": "mri1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729947", "map_id": "none", "name": "argininosuccinate <=> fumarate + arginine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_34575", "map_id": "CHEBI:15682", "name": "ARSUA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10729944", "map_id": "none", "name": "ASL tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P50514", "map_id": "P50514", "name": "argx", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC1539.03c", "map_id": "SPBC1539.03c", "name": "argx", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10757135", "map_id": "none", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10757133", "map_id": "Q9USJ1", "name": "tum1", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10740139", "map_id": "none", "name": "PXLP-K341-GPT2 transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_379697", "map_id": "CHEBI:57972", "name": "L-Ala", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10740136", "map_id": "none", "name": "PXLP-K341-GPT2 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10737914", "map_id": "none", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_353113", "map_id": "CHEBI:15625", "name": "dc-AdoMet", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10737911", "map_id": "Q9P7E3", "name": "spe2", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBP4H10.05c", "map_id": "SPBP4H10.05c", "name": "spe2", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10742237", "map_id": "none", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10749651", "map_id": "none", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_876", "compartment_display": "plasma membrane" }, { "id": "species_5693762", "map_id": "CHEBI:76931", "name": "NAAG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_5693772", "map_id": "CHEBI:16953", "name": "NAASP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10749648", "map_id": "none", "name": "NAALADases", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "reaction_10755607", "map_id": "none", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_6786250", "map_id": "CHEBI:15727", "name": "CARN", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_8876775", "map_id": "CHEBI:18323", "name": "Anserine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10755604", "map_id": "Q9Y7J3", "name": "CARNMT1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC1778.07", "map_id": "SPBC1778.07", "name": "CARNMT1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10730041", "map_id": "none", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_29610", "map_id": "CHEBI:17148", "name": "Putrescine", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10729917", "map_id": "none", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_113561", "map_id": "CHEBI:28938", "name": "NH4+", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29896", "map_id": "CHEBI:17544", "name": "HCO3-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_29676", "map_id": "CHEBI:58228", "name": "CAP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10729914", "map_id": "Q09794", "name": "ura1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_30471", "map_id": "CHEBI:17533", "name": "NAcGlu", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10756873", "map_id": "none", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9013543", "map_id": "LigandDisplayForward?ligandId=9830", "name": "sulfanegen", "type": "reactant", "sub_type": "other", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10756884", "map_id": "none", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_376186", "map_id": "CHEBI:16523", "name": "D-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10729937", "map_id": "none", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10729934", "map_id": "none", "name": "ARG1 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10729927", "map_id": "none", "name": "carbamoyl phosphate + ornithine => citrulline + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10729924", "map_id": "none", "name": "OTC trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P31317", "map_id": "P31317", "name": "arg3", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC4G9.10", "map_id": "SPAC4G9.10", "name": "arg3", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756887", "map_id": "none", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10755833", "map_id": "none", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8932979", "map_id": "CHEBI:33384", "name": "L-Ser", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "species_10755830", "map_id": "none", "name": "SERINC3,5,(1,2,4)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "true" }, { "id": "Q9HDY3", "map_id": "Q9HDY3", "name": "SERINC5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAPB1A10.07c", "map_id": "SPAPB1A10.07c", "name": "SERINC5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10756669", "map_id": "none", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_9012724", "map_id": "CHEBI:17137", "name": "HSO3-", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10741579", "map_id": "none", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10741576", "map_id": "none", "name": "MTAP trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q09816", "map_id": "Q09816", "name": "MTAP", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPAC16C9.02c", "map_id": "SPAC16C9.02c", "name": "MTAP", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10737906", "map_id": "none", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10737903", "map_id": "Q09741", "name": "SRM", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPBC12C2.07c", "map_id": "SPBC12C2.07c", "name": "SRM", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10729958", "map_id": "none", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10742227", "map_id": "none", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1614582", "map_id": "CHEBI:21347", "name": "L-Lanthionine", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10729909", "map_id": "none", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_10729906", "map_id": "P31318", "name": "arg11", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "SPAC4G9.09c", "map_id": "SPAC4G9.09c", "name": "arg11", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_374064", "map_id": "CHEBI:32682", "name": "L-Arg", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "reaction_10739964", "map_id": "none", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_374061", "map_id": "CHEBI:16199", "name": "Urea", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10739961", "map_id": "none", "name": "ARG2 trimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "P37818", "map_id": "P37818", "name": "car1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP26C9.02c", "map_id": "SPBP26C9.02c", "name": "car1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10734644", "map_id": "none", "name": "PLK1 phosphorylates NUDC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734638", "map_id": "O60166", "name": "nudc", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC19F8.02", "map_id": "SPBC19F8.02", "name": "phospho-nudc", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10734642", "map_id": "O60166", "name": "phospho-nudc", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10734452", "map_id": "none", "name": "Separation of elongating transcript from template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734448", "map_id": "none", "name": "Elongation complex prior to separation", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10734450", "map_id": "none", "name": "Elongation complex with separated and uncleaved transcript", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734466", "map_id": "none", "name": "Pol II elongation complex moves on the template as transcript elongates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10734438", "map_id": "none", "name": "Addition of nucleotides leads to transcript elongation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734434", "map_id": "none", "name": "Elongation complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734460", "map_id": "none", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10734363", "map_id": "none", "name": "RNA Pol II (hypophosphorylated):capped pre-mRNA complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10734365", "map_id": "none", "name": "RNA Pol II (hypophosphorylated) complex bound to DSIF protein", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734370", "map_id": "none", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10730702", "map_id": "none", "name": "capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10734304", "map_id": "Q9P376", "name": "fcp1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10742959", "map_id": "none", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_265283", "map_id": "CHEBI:15554", "name": "PGH2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_879535", "map_id": "CHEBI:15553", "name": "PGF2a", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10737651", "map_id": "none", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_265287", "map_id": "CHEBI:15551", "name": "PGE2", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10742962", "map_id": "none", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_879629", "map_id": "CHEBI:15555", "name": "PGD2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_2142710", "map_id": "CHEBI:27595", "name": "11epi-PGF2a", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10748696", "map_id": "none", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_5690044", "map_id": "none", "name": "MCFA-CoA, LCFA-CoA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:33184", "map_id": "CHEBI:33184", "name": "CHEBI:33184", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "CHEBI:61907", "map_id": "CHEBI:61907", "name": "CHEBI:61907", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_5690064", "map_id": "none", "name": "MCFA, LCFA", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "CHEBI:59554", "map_id": "CHEBI:59554", "name": "CHEBI:59554", "type": "complex_component", "sub_type": "metabolite_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10748693", "map_id": "none", "name": "ACOT13 tetramer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "P87304", "map_id": "P87304", "name": "ACOT13", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBC31F10.02", "map_id": "SPBC31F10.02", "name": "ACOT13", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10755098", "map_id": "none", "name": "PAFAH2 hydrolyses PAF to lyso-PAF and acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane" }, { "id": "species_8869214", "map_id": "CHEBI:52450", "name": "PAF", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_8869207", "map_id": "CHEBI:91144", "name": "lyso-PAF", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "species_10755095", "map_id": "Q9URV1", "name": "plg7", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "false" }, { "id": "SPBC106.11c", "map_id": "SPBC106.11c", "name": "plg7", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10746338", "map_id": "none", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10744090", "map_id": "none", "name": "PRDX1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "species_10746335", "map_id": "none", "name": "HOOS-C52-PRDX1 dimer", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "reaction_10735170", "map_id": "none", "name": "Formation of TSC1:TSC2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10735164", "map_id": "Q09778", "name": "tsc1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_876", "compartment_display": "plasma membrane", "complex": "false" }, { "id": "reaction_10757294", "map_id": "none", "name": "Unwinding of DNA for the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733310", "map_id": "none", "name": "pol II transcription complex containing 3 Nucleotide long transcript", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733352", "map_id": "none", "name": "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733350", "map_id": "none", "name": "pol II transcription complex containing 4 nucleotide long transcript", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10734065", "map_id": "none", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733549", "map_id": "none", "name": "pol II transcription complex containing 11 nucleotide long transcript", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733586", "map_id": "none", "name": "Pol II transcription complex containing extruded transcript to +30", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10753227", "map_id": "none", "name": "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10753215", "map_id": "none", "name": "RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10753224", "map_id": "none", "name": "RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733584", "map_id": "none", "name": "RNA Polymerase II CTD (phosphorylated) binds to CE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733582", "map_id": "none", "name": "Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733576", "map_id": "P40997", "name": "ceg1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPBC2F12.08c", "map_id": "SPBC2F12.08c", "name": "ceg1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733578", "map_id": "none", "name": "RNA Pol II with phosphorylated CTD: CE complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "P40997", "map_id": "P40997", "name": "ceg1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10733356", "map_id": "none", "name": "Addition of Nucleotides 5 through 9 on the growing Transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733354", "map_id": "none", "name": "pol II transcription complex containing 9 nucleotide long transcript", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10757296", "map_id": "none", "name": "Unwinding DNA for the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10734472", "map_id": "none", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10733580", "map_id": "none", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10733604", "map_id": "none", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733594", "map_id": "O74880", "name": "pcm1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "SPCC330.10", "map_id": "SPCC330.10", "name": "pcm1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "species_10733602", "map_id": "none", "name": "CE:Pol II CTD:Spt5 complex", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "O74880", "map_id": "O74880", "name": "pcm1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10733415", "map_id": "none", "name": "RNA Polymerase II Promoter Opening: First Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10733589", "map_id": "none", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10733551", "map_id": "none", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10752508", "map_id": "none", "name": "PLK3 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10752503", "map_id": "P06652", "name": "phospho-cdc25", "type": "product", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10752505", "map_id": "P50528", "name": "plo1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10733313", "map_id": "none", "name": "Addition of the third nucleotide on the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10757952", "map_id": "none", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10736294", "map_id": "none", "name": "HSD11B2,HSD11B1 dimer oxidise CORT to COR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_17957", "compartment_display": "endoplasmic reticulum lumen" }, { "id": "species_193977", "map_id": "CHEBI:17650", "name": "CORT", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_194035", "map_id": "CHEBI:16962", "name": "COR", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10736291", "map_id": "none", "name": "Homologues of HSD11B2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10740318", "map_id": "none", "name": "HSD17B1 hydrogenates E1 to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_10740315", "map_id": "none", "name": "HSD17B1 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O74628", "map_id": "O74628", "name": "HSD17B1", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC162.03", "map_id": "SPCC162.03", "name": "HSD17B1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10736285", "map_id": "none", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_196366", "map_id": "CHEBI:63843", "name": "pregn-5-ene-3,20-dione-17-ol", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_193092", "map_id": "CHEBI:17252", "name": "17aHPROG", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10750043", "map_id": "none", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix" }, { "id": "species_5696835", "map_id": "CHEBI:16469", "name": "EST17b", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_5696848", "map_id": "CHEBI:17263", "name": "E1", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "false" }, { "id": "species_10750040", "map_id": "none", "name": "Homologues of AKR1B15", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_5460", "compartment_display": "mitochondrial matrix", "complex": "true" }, { "id": "reaction_10736362", "map_id": "none", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_193124", "map_id": "CHEBI:28750", "name": "17aHPREG", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10754586", "map_id": "none", "name": "HSD17B2 oxidises estradiol (E2) to estrone (E1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176619", "map_id": "CHEBI:16469", "name": "E2", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10754583", "map_id": "none", "name": "Homologues of HSD17B2", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_12045", "compartment_display": "endoplasmic reticulum membrane", "complex": "true" }, { "id": "reaction_10736243", "map_id": "none", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_176626", "map_id": "CHEBI:28689", "name": "DHEA", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10743335", "map_id": "none", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2509848", "map_id": "CHEBI:61314", "name": "XTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10743329", "map_id": "none", "name": "ITPA dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9UU89", "map_id": "Q9UU89", "name": "ITPA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC830.10", "map_id": "SPCC830.10", "name": "ITPA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743338", "map_id": "none", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_2509835", "map_id": "CHEBI:61382", "name": "dITP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_9731659", "map_id": "CHEBI:61194", "name": "dIMP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "reaction_10732747", "map_id": "none", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_30064", "map_id": "CHEBI:17712", "name": "XAN", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10732744", "map_id": "none", "name": "GDA dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "O14057", "map_id": "O14057", "name": "GDA", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPCC1672.03c", "map_id": "SPCC1672.03c", "name": "GDA", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743097", "map_id": "none", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_1131972", "map_id": "CHEBI:57967", "name": "ADP-D-ribose", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10743094", "map_id": "none", "name": "NUDT5 dimer", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "true" }, { "id": "Q9P791", "map_id": "Q9P791", "name": "NUDT5", "type": "complex_component", "sub_type": "protein_component", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "SPBP35G2.12", "map_id": "SPBP35G2.12", "name": "NUDT5", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10743332", "map_id": "none", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "reaction_10756339", "map_id": "none", "name": "DNPH1 hydrolyses dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_70101", "compartment_display": "cytosol" }, { "id": "species_8953344", "map_id": "CHEBI:62877", "name": "2DORP", "type": "product", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "species_10756336", "map_id": "Q9Y7P9", "name": "DNPH1", "type": "catalyst", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_70101", "compartment_display": "cytosol", "complex": "false" }, { "id": "SPCC191.05c", "map_id": "SPCC191.05c", "name": "DNPH1", "type": "gene_component", "sub_type": "gene", "inferred": "false", "compartment": "none", "compartment_display": "none" }, { "id": "reaction_10733620", "map_id": "none", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_113571", "map_id": "CHEBI:37565", "name": "GTP", "type": "reactant", "sub_type": "metabolite_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10733610", "map_id": "none", "name": "Capping complex (hydrolyzed)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733617", "map_id": "none", "name": "Capping complex (intermediate)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733608", "map_id": "none", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_72084", "map_id": "none", "name": "nascent pre-mRNA transcript", "type": "reactant", "sub_type": "", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10733606", "map_id": "none", "name": "Capping complex (initial)", "type": "catalyst", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733634", "map_id": "none", "name": "Methylation of GMP-cap by RNA Methyltransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733627", "map_id": "none", "name": "Capping complex (with freed 5'- GMP)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10733631", "map_id": "none", "name": "mRNA capping factors", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "species_10730700", "map_id": "none", "name": "RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA", "type": "reactant", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733629", "map_id": "none", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10733622", "map_id": "none", "name": "Capping complex (GpppN..)", "type": "product", "sub_type": "complex_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "true" }, { "id": "reaction_10733636", "map_id": "none", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "species_10730619", "map_id": "O14253", "name": "cbc1", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "species_10730614", "map_id": "Q9P383", "name": "cbc2", "type": "reactant", "sub_type": "protein_component", "inferred": "false", "compartment": "compartment_7660", "compartment_display": "nucleoplasm", "complex": "false" }, { "id": "reaction_10733625", "map_id": "none", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10733613", "map_id": "none", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "type": "reaction", "sub_type": "reaction", "compartment": "compartment_7660", "compartment_display": "nucleoplasm" }, { "id": "reaction_10733638", "map_id": "none", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. 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High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733718", "species_10736485" ], "products": [ "species_10736487" ], "modifiers": [], "additional_components": [ "species_179838", "Q12701", "SPCC576.15c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q12701", "SPCC576.15c" ] }, "reaction_10730559": { "compartment": "compartment_70101", "id": "reaction_10730559", "reactome": "R-SPO-71732", "name": "PPA1 hydrolyzes pyrophosphate to orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10730556", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P87118", "SPAC3A12.02", "P19117", "SPAC23C11.05" ] }, "reaction_10739587": { "compartment": "compartment_12045", "id": "reaction_10739587", "reactome": "R-SPO-446214", "name": "Synthesis of dolichyl-phosphate-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_449299" ], "products": [ "species_110096", "species_532214" ], "modifiers": [ [ "species_10739584", "catalyst" ] ], "additional_components": [ "SPBC56F2.10c" ] }, "reaction_10750117": { "compartment": "compartment_7660", "id": "reaction_10750117", "reactome": "R-SPO-6781818", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5688114", "species_10732494", "species_10730706" ], "products": [ "species_10750115" ], "modifiers": [], "additional_components": [ "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q02061", "SPAC23G3.01", "P36594", "SPBC28F2.12", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O13877", "SPAC1B3.12c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O14459", "SPACUNK4.06c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10750180": { "compartment": "compartment_7660", "id": "reaction_10750180", "reactome": "R-SPO-6781833", "name": "ERCC8 (CSA) binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750176", "species_10750129" ], "products": [ "species_10750167", "species_10750178" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9UT51", "SPAC222.16c", "O14122", "SPAC3A11.08", "O94308", "SPBC215.03c", "Q9UUJ7", "SPAC1952.12c", "O13895", "SPAC22A12.03c", "O94454", "SPAC1687.13c", "Q9USR0", "SPBC577.09", "Q9HFR0", "SPAPB17E12.04c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "Q9UT51", "SPAC222.16c", "O94308", "SPBC215.03c", "Q9UUJ7", "SPAC1952.12c", "O13895", "SPAC22A12.03c", "O94454", "SPAC1687.13c", "Q9HFR0", "SPAPB17E12.04c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10750201": { "compartment": "compartment_7660", "id": "reaction_10750201", "reactome": "R-SPO-6781867", "name": "ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729044", "species_10750178" ], "products": [ "species_10750198" ], "modifiers": [ [ "species_10750178", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10750122": { "compartment": "compartment_7660", "id": "reaction_10750122", "reactome": "R-SPO-6781824", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6781829", "species_10750115" ], "products": [ "species_10750119", "species_113541" ], "modifiers": [ [ "species_10750115", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10750235": { "compartment": "compartment_7660", "id": "reaction_10750235", "reactome": "R-SPO-6782069", "name": "UVSSA:USP7 deubiquitinates ERCC6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10750226" ], "products": [ "species_10729044", "species_10750232" ], "modifiers": [ [ "species_10750226", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750182": { "compartment": "compartment_7660", "id": "reaction_10750182", "reactome": "R-SPO-6781840", "name": "ERCC6 binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750119", "species_10750127" ], "products": [ "species_10750129" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "SPCP25A2.02c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10739167": { "compartment": "compartment_70101", "id": "reaction_10739167", "reactome": "R-SPO-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739153", "species_429974" ], "products": [ "species_10739155" ], "modifiers": [], "additional_components": [ "O74499", "SPCC285.12", "O94408", "SPCC1620.01c", "Q9Y7M4", "SPBC9B6.05c", "O42978", "SPBC20F10.09", "Q9UUI1", "SPAC2F3.17c", "O42958", "SPBC19G7.10c", "P87173", "SPBC3D6.08c", "O14352", "SPBC30D10.06", "O74499", "SPCC285.12", "O94408", "SPCC1620.01c", "Q9Y7M4", "SPBC9B6.05c", "O42978", "SPBC20F10.09", "Q9UUI1", "SPAC2F3.17c", "O42958", "SPBC19G7.10c", "P87173", "SPBC3D6.08c", "O14352", "SPBC30D10.06" ] }, "reaction_10739245": { "compartment": "compartment_70101", "id": "reaction_10739245", "reactome": "R-SPO-430028", "name": "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429974", "species_29356" ], "products": [ "species_109395", "species_109402", "species_429926", "species_76577", "species_113578" ], "modifiers": [ [ "species_10739242", "catalyst" ] ], "additional_components": [ "O42872", "SPAC3G9.10c", "O59821", "SPCC1840.11", "O94474", "SPCC1919.05", "O74774", "SPBC25B2.01", "O13903", "SPAC22A12.12c", "Q09150", "SPBC32F12.02", "O74918", "SPCC757.08", "O60124", "SPBC16G5.10", "Q9P7R3", "SPBC211.08c", "O59801", "SPCC550.03c", "Q09704", "SPAC2F7.14c", "O42894", "SPBC115.01c", "Q10205", "SPBC17D1.03c", "P37202", "SPBC26H8.10" ] }, "reaction_10739165": { "compartment": "compartment_70101", "id": "reaction_10739165", "reactome": "R-SPO-429961", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429926", "species_29356" ], "products": [ "species_429925", "species_430042" ], "modifiers": [ [ "species_10739162", "catalyst" ] ], "additional_components": [ "SPBP4H10.20" ] }, "reaction_10733646": { "compartment": "compartment_7660", "id": "reaction_10733646", "reactome": "R-SPO-77589", "name": "Recognition of AAUAAA sequence by CPSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733642", "species_10731317" ], "products": [ "species_10733644" ], "modifiers": [], "additional_components": [ "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c" ] }, "reaction_10757633": { "compartment": "compartment_17938", "id": "reaction_10757633", "reactome": "R-SPO-9646468", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757563", "species_10735183" ], "products": [ "species_10757565" ], "modifiers": [], "additional_components": [ "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "species_29438", "O94363", "SPBC428.16c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757544": { "compartment": "compartment_17938", "id": "reaction_10757544", "reactome": "R-SPO-9639286", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757537", "species_29420" ], "products": [ "species_29438", "species_10757541" ], "modifiers": [ [ "species_10757537", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757608": { "compartment": "compartment_17938", "id": "reaction_10757608", "reactome": "R-SPO-9645608", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757552", "species_10757561" ], "products": [ "species_10757563" ], "modifiers": [], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "Q9Y7K2", "SPBC216.07c", "P87141", "SPAC57A7.11", "O74184", "SPBC21B10.05c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757570": { "compartment": "compartment_17938", "id": "reaction_10757570", "reactome": "R-SPO-9640195", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757565" ], "products": [ "species_10757567", "species_29372" ], "modifiers": [ [ "species_10757565", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757557": { "compartment": "compartment_17938", "id": "reaction_10757557", "reactome": "R-SPO-9640167", "name": "RRAGA,B exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757550" ], "products": [ "species_10757554", "species_29420" ], "modifiers": [ [ "species_10757550", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "species_29468", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "species_29468", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "species_29468", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757606": { "compartment": "compartment_17938", "id": "reaction_10757606", "reactome": "R-SPO-9645598", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757537" ], "products": [ "species_29372", "species_10757541" ], "modifiers": [ [ "species_10757537", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10733230": { "compartment": "compartment_70101", "id": "reaction_10733230", "reactome": "R-SPO-75125", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500006", "species_29370" ], "products": [ "species_113592", "species_500009" ], "modifiers": [ [ "species_10732253", "catalyst" ] ], "additional_components": [ "species_110096", "species_110094", "CHEBI:58593", "species_109395", "species_109378", "species_418075", "SPCC1795.05c" ] }, "reaction_10740122": { "compartment": "compartment_5460", "id": "reaction_10740122", "reactome": "R-SPO-482804", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_482803", "species_113593" ], "products": [ "species_482807", "species_113581" ], "modifiers": [ [ "species_10740119", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "P49740", "SPAC806.07" ] }, "reaction_10732360": { "compartment": "compartment_70101", "id": "reaction_10732360", "reactome": "R-SPO-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10732357", "catalyst" ] ], "additional_components": [ "O42644", "SPAC10F6.03c" ] }, "reaction_10750485": { "compartment": "compartment_7660", "id": "reaction_10750485", "reactome": "R-SPO-6788810", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788813", "species_29358" ], "products": [ "species_113582", "species_6788807" ], "modifiers": [ [ "species_10750482", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "SPCC830.11c" ] }, "reaction_10734110": { "compartment": "compartment_70101", "id": "reaction_10734110", "reactome": "R-SPO-111751", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10732350" ], "products": [ "species_10732348", "species_8866399", "species_29356" ], "modifiers": [ [ "species_10734107", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "P36603", "SPBC25D12.04", "P36602", "SPAC1F7.05", "CHEBI:29034" ] }, "reaction_10734119": { "compartment": "compartment_70101", "id": "reaction_10734119", "reactome": "R-SPO-111804", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10732350" ], "products": [ "species_10732348", "species_8866399", "species_29356" ], "modifiers": [ [ "species_10734116", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "P36602", "SPAC1F7.05", "P36603", "SPBC25D12.04", "CHEBI:29034" ] }, "reaction_10740066": { "compartment": "compartment_70101", "id": "reaction_10740066", "reactome": "R-SPO-482621", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_482625" ], "products": [ "species_482627", "species_113592" ], "modifiers": [ [ "species_10740061", "catalyst" ] ], "additional_components": [ "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "P49740", "SPAC806.07" ] }, "reaction_10733852": { "compartment": "compartment_70101", "id": "reaction_10733852", "reactome": "R-SPO-110145", "name": "AMP + ATP <=> ADP + ADP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76577" ], "products": [ "species_29370" ], "modifiers": [ [ "species_10733847", "catalyst" ] ], "additional_components": [ "SPAC4G9.03" ] }, "reaction_10732370": { "compartment": "compartment_7660", "id": "reaction_10732370", "reactome": "R-SPO-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742", "species_9668967" ], "modifiers": [ [ "species_10732367", "catalyst" ] ], "additional_components": [ "Q9P6Q5", "SPAC644.05c" ] }, "reaction_10732510": { "compartment": "compartment_70101", "id": "reaction_10732510", "reactome": "R-SPO-73788", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500071", "species_113592" ], "products": [ "species_500077", "species_29370" ], "modifiers": [ [ "species_10732507", "catalyst" ] ], "additional_components": [ "species_109327", "species_29626", "species_29420", "CHEBI:58595", "SPBC1198.05" ] }, "reaction_10752646": { "compartment": "compartment_70101", "id": "reaction_10752646", "reactome": "R-SPO-6806877", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8866401" ], "products": [ "species_29370", "species_6806881" ], "modifiers": [ [ "species_10752643", "catalyst" ] ], "additional_components": [ "P49740", "SPAC806.07" ] }, "reaction_10732322": { "compartment": "compartment_70101", "id": "reaction_10732322", "reactome": "R-SPO-73596", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_109378", "species_29356" ], "products": [ "species_109382", "species_31633" ], "modifiers": [ [ "species_10732319", "catalyst" ] ], "additional_components": [ "O43012", "SPBC2G2.13c" ] }, "reaction_10732332": { "compartment": "compartment_70101", "id": "reaction_10732332", "reactome": "R-SPO-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109382", "species_111355" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10732329", "catalyst" ] ], "additional_components": [ "Q9UTI7", "SPAC15E1.04", "species_29926" ] }, "reaction_10740131": { "compartment": "compartment_70101", "id": "reaction_10740131", "reactome": "R-SPO-504054", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10740128", "catalyst" ] ], "additional_components": [ "O42644", "SPAC10F6.03c" ] }, "reaction_10733843": { "compartment": "compartment_70101", "id": "reaction_10733843", "reactome": "R-SPO-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_113592", "species_6788778" ], "modifiers": [ [ "species_10733838", "catalyst" ] ], "additional_components": [ "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "species_109395", "species_76577", "species_109378", "species_109386", "SPAC4G9.03" ] }, "reaction_10733845": { "compartment": "compartment_70101", "id": "reaction_10733845", "reactome": "R-SPO-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6788778" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10733838", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "SPAC4G9.03" ] }, "reaction_10730480": { "compartment": "compartment_70101", "id": "reaction_10730480", "reactome": "R-SPO-71682", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_111745" ], "products": [ "species_29366", "species_29450" ], "modifiers": [ [ "species_10730477", "catalyst" ] ], "additional_components": [ "P78965", "SPBC17A3.07", "species_113596" ] }, "reaction_10739090": { "compartment": "compartment_70101", "id": "reaction_10739090", "reactome": "R-SPO-428941", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739086", "species_113592" ], "products": [ "species_29370", "species_10739088" ], "modifiers": [ [ "species_10734141", "catalyst" ] ], "additional_components": [ "SPAC24B11.06c", "SPAC24B11.06c", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10739107": { "compartment": "compartment_70101", "id": "reaction_10739107", "reactome": "R-SPO-428961", "name": "Phosphorylation of cPLA2 by MAPK p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10739104" ], "products": [ "species_29370", "species_10734190" ], "modifiers": [ [ "species_10739088", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "SPAC24B11.06c" ] }, "reaction_10732235": { "compartment": "compartment_70101", "id": "reaction_10732235", "reactome": "R-SPO-72672", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732216", "species_10731817", "species_10732225" ], "products": [ "species_10732227" ], "modifiers": [], "additional_components": [ "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "P0C016", "SPAC6G10.11c", "O42706", "SPAC959.08", "P0C8R3", "SPAC589.10c", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O14388", "SPBC685.07c", "Q09668", "SPAC11E3.15", "P52822", "SPAC3H5.12c", "P36584", "SPAPB8E5.06c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P05733", "SPCC1223.05c", "Q9P784", "SPBC1711.06", "O74864", "SPCC18.14c", "O60143", "SPBC18H10.12c", "P0CT77", "SPAC26A3.07c", "P0CT61", "SPCC1322.11", "P79015", "SPAC3H5.10", "P35679", "SPBP8B7.03c", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "O14069", "SPAC1687.06c", "Q09127", "SPBC18E5.04", "P0CT72", "SPBC839.04", "P08094", "SPBP8B7.06", "O94238", "SPAC1805.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "Q9P769", "SPAP7G5.05", "P0CT68", "SPAC3A12.10", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "Q9USR7", "SPBC577.02", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O74904", "SPCC613.05c", "O42699", "SPCC1682.14", "P40372", "SPAC17A5.03", "P0CT83", "SPCC16C4.13c", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07", "Q9US22", "SPAC1783.08c", "O59675", "SPBC29A3.12", "Q9P7B2", "SPAC521.05", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P0CT74", "SPAC144.11", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P87158", "SPBC19F8.08", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0CT76", "SPBP4H10.13", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT80", "SPCC285.15c", "P0CT64", "SPBC18H10.14", "Q9UTG4", "SPAC1805.11c", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "P0CT58", "SPAC22A12.04c", "O13614", "SPBP22H7.08", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q9UTQ6", "SPAC1071.07c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "Q9P4W9", "SPAC959.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "O74172", "SPBC3D6.15", "P0CT66", "SPBC16D10.11c", "Q10251", "SPAC56F8.03", "species_29438", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "Q10251", "SPAC56F8.03", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "P79015", "SPAC3H5.10", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "Q09127", "SPBC18E5.04", "P08094", "SPBP8B7.06", "P0CT76", "SPBP4H10.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "O74893", "SPCC576.09", "P0CT68", "SPAC3A12.10", "Q9P3T6", "SPAC328.10c", "Q9USR7", "SPBC577.02", "Q9UTG4", "SPAC1805.11c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O42699", "SPCC1682.14", "P0CT83", "SPCC16C4.13c", "Q9P4W9", "SPAC959.07", "Q9US22", "SPAC1783.08c", "O74172", "SPBC3D6.15", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "Q9P546", "SPAPJ698.02c", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07" ] }, "reaction_10732233": { "compartment": "compartment_70101", "id": "reaction_10732233", "reactome": "R-SPO-72671", "name": "eIF5B:GTP is hydrolyzed and released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732227" ], "products": [ "species_10732231", "species_10732229", "species_29372" ], "modifiers": [], "additional_components": [ "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "Q10251", "SPAC56F8.03", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", "SPAC25G10.06", "Q9USW5", 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been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_10731778", "species_10734741" ], "products": [ "species_10731755", "species_10731810" ], "modifiers": [], "additional_components": [ "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "O74743", "SPBC1709.18", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10734671": { "compartment": "compartment_70101", "id": "reaction_10734671", "reactome": "R-SPO-156808", "name": "Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_10734667", "species_10734655", "species_10731778" ], "products": [ "species_10731755", "species_10734669" ], "modifiers": [], "additional_components": [ "SPBC25H2.07", "Q9P6M8", "SPAC1610.03c", "P31209", "SPAC57A7.04c", "O74743", "SPBC1709.18", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "SPBC25H2.07", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10732241": { "compartment": "compartment_70101", "id": "reaction_10732241", "reactome": "R-SPO-72676", "name": "eIF3 and eIF1A bind to the 40S subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_10731750", "species_10731692" ], "products": [ "species_10732239" ], "modifiers": [], "additional_components": [ "SPBC25H2.07", "Q09722", "SPAC1751.03", "O94513", "SPBC646.09c", "Q10425", "SPAC25G10.08", "P79083", "SPAC4D7.05", "P87128", "SPAC3A12.13c", "O43060", "SPBC4C3.07", "Q9UT48", "SPAC821.05", "P78795", "SPBC18H10.03", "O94236", "SPAC637.07", "O74760", "SPBC17D11.05", "O14164", "SPAC4A8.16c", "O59675", "SPBC29A3.12", "Q9P7B2", "SPAC521.05", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P0CT74", "SPAC144.11", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P87158", "SPBC19F8.08", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0CT76", "SPBP4H10.13", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT80", "SPCC285.15c", "P0CT64", "SPBC18H10.14", "Q9UTG4", "SPAC1805.11c", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "P0CT58", "SPAC22A12.04c", "O13614", "SPBP22H7.08", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q9UTQ6", "SPAC1071.07c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "Q9P4W9", "SPAC959.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "O74172", "SPBC3D6.15", "P0CT66", "SPBC16D10.11c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10731821": { "compartment": "compartment_70101", "id": "reaction_10731821", "reactome": "R-SPO-72621", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10731810" ], "products": [ "species_29370", "species_10731810", "species_29372" ], "modifiers": [ [ "species_72617", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10732237": { "compartment": "compartment_70101", "id": "reaction_10732237", "reactome": "R-SPO-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_10732218" ], "products": [ "species_10731755", "species_10732216", "species_10731692" ], "modifiers": [], "additional_components": [ "SPBC25H2.07", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", "SPAC25G10.06", 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"SPCC24B10.09", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT80", "SPCC285.15c", "P0CT64", "SPBC18H10.14", "Q9UTG4", "SPAC1805.11c", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "P0CT58", "SPAC22A12.04c", "O13614", "SPBP22H7.08", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q9UTQ6", "SPAC1071.07c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "Q9P4W9", "SPAC959.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "O74172", "SPBC3D6.15", "P0CT66", "SPBC16D10.11c" ] }, "reaction_10731831": { "compartment": "compartment_70101", "id": "reaction_10731831", "reactome": "R-SPO-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731774", "species_72393" ], "products": [ "species_10731776" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c" ] }, "reaction_10731823": { "compartment": "compartment_70101", "id": "reaction_10731823", "reactome": "R-SPO-72631", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731789", "species_10731794", "species_10731799" ], "products": [ "species_10731801" ], "modifiers": [], "additional_components": [ "P47943", "SPAC1006.07", "SPBC1709.18", "SPAC17C9.03", "O74743", "SPBC1709.18", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07" ] }, "reaction_10731829": { "compartment": "compartment_70101", "id": "reaction_10731829", "reactome": "R-SPO-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10731772" ], "products": [ "species_10731774" ], "modifiers": [], "additional_components": [ "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c" ] }, "reaction_10732248": { "compartment": "compartment_70101", "id": "reaction_10732248", "reactome": "R-SPO-72722", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10731860" ], "products": [ "species_10731858", "species_10731774", "species_29420" ], "modifiers": [ [ "species_10731858", "catalyst" ] ], "additional_components": [ "species_29420", "P56286", "SPAC3G9.09c", "P56288", "SPAC4D7.09", "Q09130", "SPBC17G9.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "P56329", "SPAC32A11.04c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06", "P56288", "SPAC4D7.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c", "P56288", "SPAC4D7.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06" ] }, "reaction_10731862": { "compartment": "compartment_70101", "id": "reaction_10731862", "reactome": "R-SPO-72670", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731819", "species_10731858" ], "products": [ "species_10731860" ], "modifiers": [], "additional_components": [ "species_29420", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c", "P56288", "SPAC4D7.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06", "species_29420", "P56286", "SPAC3G9.09c", "P56288", "SPAC4D7.09", "Q09130", "SPBC17G9.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "P56329", "SPAC32A11.04c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06" ] }, "reaction_10732245": { "compartment": "compartment_70101", "id": "reaction_10732245", "reactome": "R-SPO-72697", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_72617", "species_10731810", "species_10731815", "species_10731772" ], "products": [ "species_10731755", "species_72617", "species_10731810", "species_10731815", "species_10731772" ], "modifiers": [ [ "species_72617", "catalyst" ] ], "additional_components": [ "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "SPAC2F7.05c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c", "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "SPAC2F7.05c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c" ] }, "reaction_10732243": { "compartment": "compartment_70101", "id": "reaction_10732243", "reactome": "R-SPO-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732239", "species_10731776" ], "products": [ "species_10731778" ], "modifiers": [], "additional_components": [ "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10738284": { "compartment": "compartment_70101", "id": "reaction_10738284", "reactome": "R-SPO-389540", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_389545" ], "products": [ "species_70106", "species_29364", "species_113528", "species_29406" ], "modifiers": [ [ "species_10738281", "catalyst" ] ], "additional_components": [ "O14254", "SPAC6G10.08" ] }, "reaction_10734757": { "compartment": "compartment_13231", "id": "reaction_10734757", "reactome": "R-SPO-158481", "name": "Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734069" ], "products": [ "species_10734755" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10734749": { "compartment": "compartment_13231", "id": "reaction_10734749", "reactome": "R-SPO-158441", "name": "Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733677" ], "products": [ "species_10734747" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10733679": { "compartment": "compartment_7660", "id": "reaction_10733679", "reactome": "R-SPO-77594", "name": "Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733165", "species_10733675", "species_10730903" ], "products": [ "species_10730621", "species_10733677", "species_10731317" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1921.03c", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "SPCC126.11c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10733226": { "compartment": "compartment_13231", "id": "reaction_10733226", "reactome": "R-SPO-75097", "name": "Transport of the export-competent mRNP complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733177" ], "products": [ "species_10733219" ], "modifiers": [ [ "species_10733155", "catalyst" ], [ "species_10733224", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "O94403", "SPCC126.11c", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "Q10267", "SPAC13G7.03", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9P383", "SPBC13A2.01c", "Q9URX8", "SPAC890.06", "Q10055", "SPAC1F5.10", "Q10168", "SPAC26A3.15c", "Q1MTR2", "SPBC13G1.14c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "O14253", "SPAC6G10.07", "Q09793", "SPAC22G7.09c", "P0CAN8", "SPAPB1A10.03", "O43044", "SPBC3B9.16c", "Q9Y8G3", "SPBC1921.03c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "O94403", "SPCC126.11c", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "Q10267", "SPAC13G7.03", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9P383", "SPBC13A2.01c", "Q9URX8", "SPAC890.06", "Q10055", "SPAC1F5.10", "Q10168", "SPAC26A3.15c", "Q1MTR2", "SPBC13G1.14c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "O14253", "SPAC6G10.07", "P0CAN8", "SPAPB1A10.03", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c", "SPBC31E1.05" ] }, "reaction_10734071": { "compartment": "compartment_7660", "id": "reaction_10734071", "reactome": "R-SPO-111439", "name": "Docking of Mature Histone mRNA complex:TAP at the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733165", "species_10730903", "species_10734067" ], "products": [ "species_10730621", "species_10734069" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1921.03c", "SPCC126.11c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10734761": { "compartment": "compartment_70101", "id": "reaction_10734761", "reactome": "R-SPO-158484", "name": "Release of the SLBP independent Histone mRNA from the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731794", "species_10734755" ], "products": [ "species_10734759", "species_10733187", "species_10733203" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1709.18", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "O74743", "SPBC1709.18", "SPBC1921.03c", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10734766": { "compartment": "compartment_7660", "id": "reaction_10734766", "reactome": "R-SPO-159101", "name": "NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733169", "species_10731417" ], "products": [ "species_113550", "species_10733175", "species_10734763" ], "modifiers": [ [ "species_10731417", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "P0CAN8", "SPAPB1A10.03", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "Q9P383", "SPBC13A2.01c", "C6Y4C0", "SPAC222.18", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "Q10267", "SPAC13G7.03", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q9Y8G3", "SPBC1921.03c", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "Q9USY2", "SPBC1861.04c", "Q10055", "SPAC1F5.10", "Q9Y7Y2", "SPBC365.05c", "Q1MTR2", "SPBC13G1.14c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "P0CAN8", "SPAPB1A10.03", "Q10267", "SPAC13G7.03", "species_29370", "O13792", "SPAC17G6.14c", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "Q9P383", "SPBC13A2.01c", "C6Y4C0", "SPAC222.18", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "Q10267", "SPAC13G7.03" ] }, "reaction_10734753": { "compartment": "compartment_70101", "id": "reaction_10734753", "reactome": "R-SPO-158447", "name": "Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731794", "species_10734747" ], "products": [ "species_10734751", "species_10733187", "species_10733203" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1709.18", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "O74743", "SPBC1709.18", "SPBC1921.03c", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10746231": { "compartment": "compartment_7660", "id": "reaction_10746231", "reactome": "R-SPO-5625784", "name": "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10746219" ], "products": [ "species_113582", "species_10746228" ], "modifiers": [ [ "species_10746219", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c" ] }, "reaction_10746240": { "compartment": "compartment_7660", "id": "reaction_10746240", "reactome": "R-SPO-5625796", "name": "Demethylase KDM4C binds KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746236", "species_10746228" ], "products": [ "species_10746238" ], "modifiers": [], "additional_components": [ "SPBC83.07", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "O94691", "SPBC83.07", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c" ] }, "reaction_10746249": { "compartment": "compartment_7660", "id": "reaction_10746249", "reactome": "R-SPO-5625797", "name": "KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10746238", "species_113685" ], "products": [ "species_10746236", "species_159942", "species_159939", "species_29478", "species_10746246" ], "modifiers": [ [ "species_10746238", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "O94691", "SPBC83.07", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "SPBC83.07", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "O94691", "SPBC83.07", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c" ] }, "reaction_10740388": { "compartment": "compartment_17957", "id": "reaction_10740388", "reactome": "R-SPO-901047", "name": "Binding of ERp57", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740236", "species_10740384" ], "products": [ "species_10740386" ], "modifiers": [], "additional_components": [ "SPAC1F5.02", "Q9P7D0", "SPBP4H10.19c", "P36581", "SPAC3C7.11c", "CHEBI:59080", "Q9P7D0", "SPBP4H10.19c", "P36581", "SPAC3C7.11c", "Q10057", "SPAC1F5.02", "CHEBI:59080" ] }, "reaction_10741489": { "compartment": "compartment_70101", "id": "reaction_10741489", "reactome": "R-SPO-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741485" ], "products": [ "species_10741487" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "CHEBI:59092", "CHEBI:60627", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "CHEBI:59087", "CHEBI:60629", "CHEBI:60628", "P0CH06", "SPAC11G7.04" ] }, "reaction_10750397": { "compartment": "compartment_1660541", "id": "reaction_10750397", "reactome": "R-SPO-6784738", "name": "Degradation of PCSK9:LDLR:Clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750393" ], "products": [ "species_10750391" ], "modifiers": [], "additional_components": [ "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P40903", "SPAC4A8.04", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10750395": { "compartment": "compartment_1660541", "id": "reaction_10750395", "reactome": "R-SPO-6784729", "name": "PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750361" ], "products": [ "species_10750393" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "P40903", "SPAC4A8.04", "Q9C0W7", "SPBC691.03c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P40903", "SPAC4A8.04" ] }, "reaction_10754372": { "compartment": "compartment_876", "id": "reaction_10754372", "reactome": "R-SPO-8855130", "name": "VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754362" ], "products": [ "species_10754370" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P40903", "SPAC4A8.04", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "P40903", "SPAC4A8.04", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10753477": { "compartment": "compartment_70101", "id": "reaction_10753477", "reactome": "R-SPO-6813720", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163579", "species_29356" ], "products": [ "species_216762", "species_8876730" ], "modifiers": [ [ "species_10753474", "catalyst" ] ], "additional_components": [ "Q9US38", "SPAPB1A11.02", "Q9HDX3", "SPAPB1A11.02" ] }, "reaction_10735593": { "compartment": "compartment_70101", "id": "reaction_10735593", "reactome": "R-SPO-174401", "name": "AHCY:NAD+ tetramer hydrolyses AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71285", "species_29356" ], "products": [ "species_174369", "species_83909" ], "modifiers": [ [ "species_10735590", "catalyst" ] ], "additional_components": [ "O13639", "SPBC8D2.18c", "species_113526" ] }, "reaction_10735568": { "compartment": "compartment_70101", "id": "reaction_10735568", "reactome": "R-SPO-174391", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174390", "species_29356" ], "products": [ "species_111294", "species_71284", "species_29372" ], "modifiers": [ [ "species_10735565", "catalyst" ] ], "additional_components": [ "O60198", "SPBC14F5.05c", "species_74126", "species_29926" ] }, "reaction_10752211": { "compartment": "compartment_70101", "id": "reaction_10752211", "reactome": "R-SPO-6800149", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806829", "species_71284" ], "products": [ "species_6800127", "species_71285" ], "modifiers": [ [ "species_10752205", "catalyst" ] ], "additional_components": [ "Q9UT94", "SPAC323.05c", "Q09723", "SPAC31A2.02" ] }, "reaction_10735665": { "compartment": "compartment_70101", "id": "reaction_10735665", "reactome": "R-SPO-175983", "name": "COMT transfer CH3 from AdoMet to 3,4DHBNZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_175977", "species_71284" ], "products": [ "species_71285", "species_175978" ], "modifiers": [ [ "species_10735662", "catalyst" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c" ] }, "reaction_10756481": { "compartment": "compartment_7660", "id": "reaction_10756481", "reactome": "R-SPO-8979071", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111793", "species_10743943" ], "products": [ "species_10743945" ], "modifiers": [], "additional_components": [ "SPBC23E6.09", "species_113531", "O60184", "SPBC23E6.09" ] }, "reaction_10743957": { "compartment": "compartment_70101", "id": "reaction_10743957", "reactome": "R-SPO-3225851", "name": "ROS oxidize thioredoxin and activate MAP3K5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1250243", "species_10743955" ], "products": [ "species_10732348", "species_10743953" ], "modifiers": [], "additional_components": [ "P28829", "SPBC1D7.05", "O94504", "SPBC12D12.07c", "SPBC12D12.07c", "SPBC1D7.05" ] }, "reaction_10739760": { "compartment": "compartment_70101", "id": "reaction_10739760", "reactome": "R-SPO-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739740" ], "products": [ "species_10739758" ], "modifiers": [], "additional_components": [ "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c" ] }, "reaction_10743960": { "compartment": "compartment_70101", "id": "reaction_10743960", "reactome": "R-SPO-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739826", "species_113592" ], "products": [ "species_29370", "species_10739740" ], "modifiers": [ [ "species_10743953", "catalyst" ] ], "additional_components": [ "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c", "SPBC1D7.05" ] }, "reaction_10743948": { "compartment": "compartment_7660", "id": "reaction_10743948", "reactome": "R-SPO-3222593", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743936", "species_113671" ], "products": [ "species_10743938", "species_159939" ], "modifiers": [ [ "species_10743945", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_113531", "O60184", "SPBC23E6.09" ] }, "reaction_10735519": { "compartment": "compartment_70101", "id": "reaction_10735519", "reactome": "R-SPO-174203", "name": "SCF-mediated degradation of Emi1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735512" ], "products": [ "species_10729165", "species_10735517", "species_10735506" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "Q9Y709", "SPBC409.05", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O13286", "SPAC144.13c", "P78972", "SPAC821.08c", "Q9Y709", "SPBC409.05", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10735515": { "compartment": "compartment_70101", "id": "reaction_10735515", "reactome": "R-SPO-174159", "name": "Ubiquitination of Emi1 by SCF-beta-TrCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729165", "species_10735510" ], "products": [ "species_10735512" ], "modifiers": [ [ "species_10735506", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9Y709", "SPBC409.05", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "Q9Y709", "SPBC409.05", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "P0CH06", "SPAC11G7.04", "Q9Y709", "SPBC409.05", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10734603": { "compartment": "compartment_70101", "id": "reaction_10734603", "reactome": "R-SPO-141429", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734592", "species_10734597" ], "products": [ "species_10734601" ], "modifiers": [], "additional_components": [ "SPAC821.08c", "SPBC20F10.06", "P78972", "SPAC821.08c", "O14417", "SPBC20F10.06" ] }, "reaction_10735495": { "compartment": "compartment_70101", "id": "reaction_10735495", "reactome": "R-SPO-174124", "name": "Dephosphorylation of phospho-Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735485", "species_29356" ], "products": [ "species_111294", "species_10735473" ], "modifiers": [ [ "species_10735492", "catalyst" ] ], "additional_components": [ "SPAC144.13c", "SPAC144.13c", "Q9P7H1", "SPAC1782.09c" ] }, "reaction_10734605": { "compartment": "compartment_70101", "id": "reaction_10734605", "reactome": "R-SPO-141437", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734592", "species_10734582", "species_10734597", "species_10734587" ], "products": [ "species_10734599" ], "modifiers": [], "additional_components": [ "SPAC821.08c", "SPCC1322.12c", "SPBC20F10.06", "SPAC23H3.08c", "O94751", "SPCC1322.12c", "P78972", "SPAC821.08c", "O42860", "SPAC23H3.08c", "O14417", "SPBC20F10.06" ] }, "reaction_10737618": { "compartment": "compartment_70101", "id": "reaction_10737618", "reactome": "R-SPO-264615", "name": "Loading of acetylcholine in synaptic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_372511", "species_264643", "species_10737613" ], "products": [ "species_70106", "species_10737615" ], "modifiers": [ [ "species_10737597", "catalyst" ] ], "additional_components": [ "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "species_264643", "SPCC18.02" ] }, "reaction_10754876": { "compartment": "compartment_70101", "id": "reaction_10754876", "reactome": "R-SPO-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10754873", "catalyst" ] ], "additional_components": [ "O13944", "SPAC23H4.01c", "O74178", "SPBC1271.12", "O14340", "SPBC2F12.05c" ] }, "reaction_10736277": { "compartment": "compartment_70101", "id": "reaction_10736277", "reactome": "R-SPO-193816", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192194", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193835" ], "modifiers": [ [ "species_10736206", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736267": { "compartment": "compartment_70101", "id": "reaction_10736267", "reactome": "R-SPO-193755", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193745" ], "products": [ "species_29366", "species_193707" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736273": { "compartment": "compartment_70101", "id": "reaction_10736273", "reactome": "R-SPO-193789", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192189", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193724" ], "modifiers": [ [ "species_10736206", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10755031": { "compartment": "compartment_70101", "id": "reaction_10755031", "reactome": "R-SPO-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_1806234", "species_8868393" ], "modifiers": [ [ "species_10755028", "catalyst" ] ], "additional_components": [ "O13944", "SPAC23H4.01c", "O14340", "SPBC2F12.05c" ] }, "reaction_10736211": { "compartment": "compartment_70101", "id": "reaction_10736211", "reactome": "R-SPO-192160", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191980" ], "products": [ "species_29366", "species_192030" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736201": { "compartment": "compartment_70101", "id": "reaction_10736201", "reactome": "R-SPO-192067", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192195" ], "products": [ "species_29366", "species_192064" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736269": { "compartment": "compartment_70101", "id": "reaction_10736269", "reactome": "R-SPO-193758", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193760" ], "products": [ "species_29366", "species_213285" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736199": { "compartment": "compartment_70101", "id": "reaction_10736199", "reactome": "R-SPO-192036", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192064" ], "products": [ "species_29366", "species_192087" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736275": { "compartment": "compartment_70101", "id": "reaction_10736275", "reactome": "R-SPO-193800", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193829" ], "products": [ "species_29366", "species_193843" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736209": { "compartment": "compartment_70101", "id": "reaction_10736209", "reactome": "R-SPO-192097", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192114", "species_29360" ], "products": [ "species_70106", "species_73473", "species_192136" ], "modifiers": [ [ "species_10736206", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736283": { "compartment": "compartment_70101", "id": "reaction_10736283", "reactome": "R-SPO-193841", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193830" ], "products": [ "species_29366", "species_193842" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736279": { "compartment": "compartment_70101", "id": "reaction_10736279", "reactome": "R-SPO-193821", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_9617026", "species_29364" ], "products": [ "species_29366", "species_193829" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736271": { "compartment": "compartment_70101", "id": "reaction_10736271", "reactome": "R-SPO-193781", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193707" ], "products": [ "species_29366", "species_193728" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736188": { "compartment": "compartment_70101", "id": "reaction_10736188", "reactome": "R-SPO-192033", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192136" ], "products": [ "species_29366", "species_191980" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736168": { "compartment": "compartment_70101", "id": "reaction_10736168", "reactome": "R-SPO-191983", "name": "Cholesterol is hydroxylated to 25-hydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_176478", "species_29368" ], "products": [ "species_29366", "species_192148", "species_29356" ], "modifiers": [ [ "species_10736165", "catalyst" ] ], "additional_components": [ "species_113531", "Q9UUH4", "SPAC630.08c" ] }, "reaction_10736265": { "compartment": "compartment_70101", "id": "reaction_10736265", "reactome": "R-SPO-193746", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193724" ], "products": [ "species_29366", "species_193760" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736281": { "compartment": "compartment_70101", "id": "reaction_10736281", "reactome": "R-SPO-193824", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193835", "species_29364" ], "products": [ "species_29366", "species_193830" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736263": { "compartment": "compartment_876", "id": "reaction_10736263", "reactome": "R-SPO-193362", "name": "ABCB11 transports bile salts from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193416", "species_113592", "species_29356" ], "products": [ "species_29370", "species_193479", "species_29372" ], "modifiers": [ [ "species_10736260", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "CHEBI:16525", "CHEBI:28865", "CHEBI:36274", "CHEBI:17687", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274", "Q02592", "SPCC737.09c", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10756980": { "compartment": "compartment_70101", "id": "reaction_10756980", "reactome": "R-SPO-9020257", "name": "LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024893", "species_29356" ], "products": [ "species_9024879" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10757026": { "compartment": "compartment_70101", "id": "reaction_10757026", "reactome": "R-SPO-9024890", "name": "LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024873" ], "products": [ "species_9024886" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10734197": { "compartment": "compartment_12045", "id": "reaction_10734197", "reactome": "R-SPO-111883", "name": "Hydrolysis of phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_140356", "species_428981" ], "modifiers": [ [ "species_10734192", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "species_429785", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10756212": { "compartment": "compartment_70101", "id": "reaction_10756212", "reactome": "R-SPO-8951727", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734228", "species_30389" ], "products": [ "species_10734230" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "P40376", "SPBC106.10", "P36600", "SPAC8C9.03", "species_30389", "P40376", "SPBC106.10" ] }, "reaction_10735214": { "compartment": "compartment_947587", "id": "reaction_10735214", "reactome": "R-SPO-167415", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734141", "species_29420" ], "products": [ "species_29438", "species_10734240" ], "modifiers": [ [ "species_10734135", "catalyst" ] ], "additional_components": [ "species_29438", "Q04665", "SPAC23H3.13c", "species_29420", "Q04665", "SPAC23H3.13c", "SPAC23H3.13c" ] }, "reaction_10734214": { "compartment": "compartment_70101", "id": "reaction_10734214", "reactome": "R-SPO-111898", "name": "Phosphorylation of cPLA2 by ERK-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734211" ], "products": [ "species_29370", "species_10734190" ], "modifiers": [ [ "species_10733808", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "SPAC31G5.09c" ] }, "reaction_10734146": { "compartment": "compartment_70101", "id": "reaction_10734146", "reactome": "R-SPO-111879", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10734143", "catalyst" ] ], "additional_components": [ "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c" ] }, "reaction_10734242": { "compartment": "compartment_70101", "id": "reaction_10734242", "reactome": "R-SPO-112037", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734143", "species_29356" ], "products": [ "species_10734124", "species_29372", "species_10734240" ], "modifiers": [], "additional_components": [ "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c", "SPAC22F8.11", "species_29420", "Q04665", "SPAC23H3.13c" ] }, "reaction_10739391": { "compartment": "compartment_70101", "id": "reaction_10739391", "reactome": "R-SPO-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10739383" ], "products": [ "species_113582", "species_10739388" ], "modifiers": [ [ "species_10739383", "catalyst" ] ], "additional_components": [ "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05" ] }, "reaction_10734194": { "compartment": "compartment_70101", "id": "reaction_10734194", "reactome": "R-SPO-111881", "name": "Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_10734190", "species_74016" ], "products": [ "species_10734192" ], "modifiers": [], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "species_429785", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10734234": { "compartment": "compartment_70101", "id": "reaction_10734234", "reactome": "R-SPO-111925", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734230" ], "products": [ "species_10734226", "species_10734232" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "species_30389", "P40376", "SPBC106.10", "SPBC106.10", "P36600", "SPAC8C9.03", "species_30389" ] }, "reaction_10738861": { "compartment": "compartment_70101", "id": "reaction_10738861", "reactome": "R-SPO-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426030", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10738858", "catalyst" ] ], "additional_components": [ "SPCC5E4.05c" ] }, "reaction_10749913": { "compartment": "compartment_876", "id": "reaction_10749913", "reactome": "R-SPO-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694509", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10749910", "catalyst" ] ], "additional_components": [ "SPAC22H12.03" ] }, "reaction_10743111": { "compartment": "compartment_70101", "id": "reaction_10743111", "reactome": "R-SPO-2408551", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5357707", "species_29356" ], "products": [ "species_5357652", "species_111294", "species_29372" ], "modifiers": [ [ "species_10735565", "catalyst" ] ], "additional_components": [ "O60198", "SPBC14F5.05c", "species_74126", "species_29926" ] }, "reaction_10756166": { "compartment": "compartment_70616", "id": "reaction_10756166", "reactome": "R-SPO-8949688", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8949220", "species_2889072" ], "products": [ "species_8949232", "species_2889083" ], "modifiers": [ [ "species_10756163", "catalyst" ] ], "additional_components": [ "SPAC3A12.06c" ] }, "reaction_10729369": { "compartment": "compartment_70101", "id": "reaction_10729369", "reactome": "R-SPO-68948", "name": "Ubiquitinated Orc1 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729071" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "SPBC29A10.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10729069": { "compartment": "compartment_7660", "id": "reaction_10729069", "reactome": "R-SPO-68946", "name": "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728907", "species_10729044" ], "products": [ "species_10729047" ], "modifiers": [ [ "species_10729066", "catalyst" ] ], "additional_components": [ "SPBC29A10.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC29A10.15", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12" ] }, "reaction_10728940": { "compartment": "compartment_7660", "id": "reaction_10728940", "reactome": "R-SPO-68944", "name": "Orc1 is phosphorylated by cyclin A/CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10728897" ], "products": [ "species_113582", "species_10728907", "species_10728911" ], "modifiers": [ [ "species_10728937", "catalyst" ] ], "additional_components": [ "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "SPBC29A10.15", "Q9Y794", "SPBP23A10.13", "O43114", "SPBC646.14c", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P41411", "SPBC14C8.07c", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "O74796", "SPBC2A9.12", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10729409": { "compartment": "compartment_7660", "id": "reaction_10729409", "reactome": "R-SPO-69005", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728714", "species_29358" ], "products": [ "species_113582", "species_10729384" ], "modifiers": [ [ "species_10729406", "catalyst" ] ], "additional_components": [ "SPBC14C8.07c", "SPBC14C8.07c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10729419": { "compartment": "compartment_70101", "id": "reaction_10729419", "reactome": "R-SPO-69016", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729417" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P41411", "SPBC14C8.07c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10729421": { "compartment": "compartment_7660", "id": "reaction_10729421", "reactome": "R-SPO-69019", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728861" ], "products": [ "species_10728857", "species_10728852", "species_10728828", "species_10728845" ], "modifiers": [], "additional_components": [ "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "SPAC1B2.05", "SPCC1682.02c", "SPBC4.04c", "P29458", "SPCC16A11.17", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10729073": { "compartment": "compartment_7660", "id": "reaction_10729073", "reactome": "R-SPO-68947", "name": "Ubiquitinated Orc1 enters the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729047" ], "products": [ "species_10729071" ], "modifiers": [], "additional_components": [ "SPBC29A10.15", "SPBC29A10.15" ] }, "reaction_10729413": { "compartment": "compartment_7660", "id": "reaction_10729413", "reactome": "R-SPO-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729384" ], "products": [ "species_10729411" ], "modifiers": [], "additional_components": [ "SPBC14C8.07c", "SPBC14C8.07c" ] }, "reaction_10736391": { "compartment": "compartment_70101", "id": "reaction_10736391", "reactome": "R-SPO-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73524", "species_113592" ], "products": [ "species_29386", "species_111294" ], "modifiers": [ [ "species_10736388", "catalyst" ] ], "additional_components": [ "SPCC1235.04c" ] }, "reaction_10736411": { "compartment": "compartment_70101", "id": "reaction_10736411", "reactome": "R-SPO-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10736408", "catalyst" ] ], "additional_components": [ "O74866", "SPCC18.16c", "species_29926" ] }, "reaction_10736401": { "compartment": "compartment_70101", "id": "reaction_10736401", "reactome": "R-SPO-196955", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29386", "species_29356" ], "products": [ "species_73524", "species_76577" ], "modifiers": [ [ "species_10736398", "catalyst" ] ], "additional_components": [ "O94323", "SPBC725.05c" ] }, "reaction_10738598": { "compartment": "compartment_876", "id": "reaction_10738598", "reactome": "R-SPO-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10738589", "catalyst" ] ], "additional_components": [ "SPAPB2B4.04c" ] }, "reaction_10746051": { "compartment": "compartment_876", "id": "reaction_10746051", "reactome": "R-SPO-5617178", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738595", "species_10738606" ], "products": [ "species_10746049" ], "modifiers": [], "additional_components": [ "SPAPB2B4.04c", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "Q9HDW7", "SPAPB2B4.04c", "P36587", "SPBC29A10.01" ] }, "reaction_10745982": { "compartment": "compartment_70101", "id": "reaction_10745982", "reactome": "R-SPO-5607721", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738454" ], "products": [ "species_10738454" ], "modifiers": [], "additional_components": [ "SPAC1006.09", "SPAC1006.09" ] }, "reaction_10746751": { "compartment": "compartment_70101", "id": "reaction_10746751", "reactome": "R-SPO-5668545", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10738454" ], "products": [ "species_29370", "species_10746748" ], "modifiers": [ [ "species_10738454", "catalyst" ] ], "additional_components": [ "SPAC1006.09", "SPAC1006.09", "SPAC1006.09" ] }, "reaction_10739639": { "compartment": "compartment_70101", "id": "reaction_10739639", "reactome": "R-SPO-446877", "name": "TRAF6 is K63 poly-ubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739630" ], "products": [ "species_10739636" ], "modifiers": [ [ "species_10739630", "catalyst" ] ], "additional_components": [ "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "O13924", "SPAC23C4.03", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746745": { "compartment": "compartment_70101", "id": "reaction_10746745", "reactome": "R-SPO-5668520", "name": "26Sproteasome degrades K48polyUb-NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746743" ], "products": [], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "SPAC1006.09", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10735267": { "compartment": "compartment_7660", "id": "reaction_10735267", "reactome": "R-SPO-168053", "name": "Phosphorylated MAPKs phosphorylate ATF-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10735231" ], "products": [ "species_113582", "species_10735245" ], "modifiers": [ [ "species_10735264", "catalyst" ] ], "additional_components": [ "P52890", "SPBC29B5.01", "P78962", "SPBC2F12.09c", "Q09771", "SPAC22F3.02", "P52890", "SPBC29B5.01", "P78962", "SPBC2F12.09c", "Q09771", "SPAC22F3.02", "Q09892", "SPAC24B11.06c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10739950": { "compartment": "compartment_70101", "id": "reaction_10739950", "reactome": "R-SPO-451418", "name": "Pellino ubiquitinates IRAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739939" ], "products": [ "species_10739947" ], "modifiers": [ [ "species_10739939", "catalyst" ] ], "additional_components": [ "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "O13924", "SPAC23C4.03", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10736765": { "compartment": "compartment_7660", "id": "reaction_10736765", "reactome": "R-SPO-199959", "name": "ERKs are inactivated by protein phosphatase 2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10736632" ], "products": [ "species_113550", "species_10736739" ], "modifiers": [ [ "species_10736762", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "Q10428", "SPCC188.02", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c" ] }, "reaction_10736635": { "compartment": "compartment_7660", "id": "reaction_10736635", "reactome": "R-SPO-198756", "name": "ERK1/2 phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10736617" ], "products": [ "species_113582", "species_10736623" ], "modifiers": [ [ "species_10736632", "catalyst" ] ], "additional_components": [ "SPCC4G3.08", "SPCC4G3.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10737238": { "compartment": "compartment_7660", "id": "reaction_10737238", "reactome": "R-SPO-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10736632" ], "products": [ "species_113550", "species_10736739" ], "modifiers": [ [ "species_10737231", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPBC1685.01" ] }, "reaction_10736626": { "compartment": "compartment_7660", "id": "reaction_10736626", "reactome": "R-SPO-198669", "name": "p38MAPK phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10736617" ], "products": [ "species_113582", "species_10736623" ], "modifiers": [ [ "species_10735252", "catalyst" ] ], "additional_components": [ "SPCC4G3.08", "SPCC4G3.08", "SPAC24B11.06c" ] }, "reaction_10739512": { "compartment": "compartment_12045", "id": "reaction_10739512", "reactome": "R-SPO-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449221", "species_110614" ], "products": [ "species_449299", "species_110094" ], "modifiers": [ [ "species_10739509", "catalyst" ] ], "additional_components": [ "SPCC63.10c" ] }, "reaction_10744801": { "compartment": "compartment_12045", "id": "reaction_10744801", "reactome": "R-SPO-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_4419981" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10744798", "catalyst" ] ], "additional_components": [ "SPAC7D4.09c" ] }, "reaction_10739528": { "compartment": "compartment_12045", "id": "reaction_10739528", "reactome": "R-SPO-446200", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449744", "species_29356" ], "products": [ "species_449299", "species_29372" ], "modifiers": [ [ "species_10739525", "catalyst" ] ], "additional_components": [ "SPBC530.12c" ] }, "reaction_10736144": { "compartment": "compartment_70101", "id": "reaction_10736144", "reactome": "R-SPO-191414", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191403" ], "products": [ "species_29370", "species_191362", "species_113528", "species_29372" ], "modifiers": [ [ "species_10736141", "catalyst" ] ], "additional_components": [ "O13963", "SPAC24C9.03" ] }, "reaction_10744793": { "compartment": "compartment_12045", "id": "reaction_10744793", "reactome": "R-SPO-4419978", "name": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419987", "species_191362" ], "products": [ "species_4419982" ], "modifiers": [ [ "species_10744790", "catalyst" ] ], "additional_components": [ "O14171", "SPAC4D7.04c", "Q9Y7K8", "SPBC2A9.06c" ] }, "reaction_10739410": { "compartment": "compartment_70101", "id": "reaction_10739410", "reactome": "R-SPO-445079", "name": "Phosphorylation of L1 by ERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738464", "species_113592", "species_10733808" ], "products": [ "species_29370", "species_10739408" ], "modifiers": [ [ "species_10733808", "catalyst" ] ], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "SPAC31G5.09c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "P27638", "SPAC31G5.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "SPAC31G5.09c" ] }, "reaction_10733813": { "compartment": "compartment_70101", "id": "reaction_10733813", "reactome": "R-SPO-109862", "name": "MAP2K2 phosphorylates MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10733780" ], "products": [ "species_29370", "species_10733810" ], "modifiers": [ [ "species_10733780", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13" ] }, "reaction_10738466": { "compartment": "compartment_17940", "id": "reaction_10738466", "reactome": "R-SPO-392749", "name": "Transport of L1 into endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738464" ], "products": [ "species_10738464" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10733803": { "compartment": "compartment_70101", "id": "reaction_10733803", "reactome": "R-SPO-109860", "name": "MAP2K1 phosphorylates MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10733770" ], "products": [ "species_29370", "species_10733794" ], "modifiers": [ [ "species_10733770", "catalyst" ], [ "species_10733799", "inhibitor" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "SPAC1D4.13" ] }, "reaction_10740265": { "compartment": "compartment_876", "id": "reaction_10740265", "reactome": "R-SPO-555065", "name": "Formation of clathrin coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735803", "species_29438", "species_10740252" ], "products": [ "species_10738464", "species_29372", "species_29420" ], "modifiers": [ [ "species_10740262", "catalyst" ] ], "additional_components": [ "SPBC119.05c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c" ] }, "reaction_10742224": { "compartment": "compartment_70101", "id": "reaction_10742224", "reactome": "R-SPO-1614583", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614518", "species_29356" ], "products": [ "species_29382", "species_936714", "species_111707" ], "modifiers": [ [ "species_10742218", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10744044": { "compartment": "compartment_70101", "id": "reaction_10744044", "reactome": "R-SPO-3299753", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744037" ], "products": [ "species_10744041", "species_10744022" ], "modifiers": [ [ "species_10744037", "catalyst" ] ], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "P28758", "SPAC821.10c", "species_442320", "species_437295", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552" ] }, "reaction_10744457": { "compartment": "compartment_70101", "id": "reaction_10744457", "reactome": "R-SPO-3697882", "name": "PRDX5 reduces peroxynitrite to nitrite using TXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222481", "species_10732350" ], "products": [ "species_10732348", "species_29356", "species_1222379" ], "modifiers": [ [ "species_10744099", "catalyst" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "SPCC330.06c" ] }, "reaction_10744104": { "compartment": "compartment_70101", "id": "reaction_10744104", "reactome": "R-SPO-3341343", "name": "PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29408", "species_10732350" ], "products": [ "species_10732348", "species_29356" ], "modifiers": [ [ "species_10744101", "catalyst" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "O14313", "SPCC330.06c", "O74887", "SPCC576.03c" ] }, "reaction_10744454": { "compartment": "compartment_70101", "id": "reaction_10744454", "reactome": "R-SPO-3697860", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744035", "species_10744450" ], "products": [ "species_10744452" ], "modifiers": [], "additional_components": [ "species_442320", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552" ] }, "reaction_10756210": { "compartment": "compartment_70101", "id": "reaction_10756210", "reactome": "R-SPO-8951723", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744452" ], "products": [ "species_10744037" ], "modifiers": [], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552" ] }, "reaction_10744025": { "compartment": "compartment_70101", "id": "reaction_10744025", "reactome": "R-SPO-3299691", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_1222424" ], "products": [ "species_29408", "species_29368" ], "modifiers": [ [ "species_10744022", "catalyst" ] ], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "species_437295" ] }, "reaction_10744083": { "compartment": "compartment_70616", "id": "reaction_10744083", "reactome": "R-SPO-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10734930" ], "products": [ "species_189461", "species_10734928" ], "modifiers": [], "additional_components": [ "P00046", "SPCC191.07", "CHEBI:38574", "P00046", "SPCC191.07", "CHEBI:38573" ] }, "reaction_10744079": { "compartment": "compartment_5460", "id": "reaction_10744079", "reactome": "R-SPO-3323079", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_1655882", "species_113529" ], "products": [ "species_113563", "species_1655887" ], "modifiers": [ [ "species_10744076", "catalyst" ] ], "additional_components": [ "P78965", "SPBC17A3.07", "species_113596" ] }, "reaction_10744015": { "compartment": "compartment_984", "id": "reaction_10744015", "reactome": "R-SPO-3299682", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299686", "species_351626" ], "products": [ "species_351629", "species_352327" ], "modifiers": [ [ "species_10744012", "catalyst" ] ], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "species_437295" ] }, "reaction_10744004": { "compartment": "compartment_5460", "id": "reaction_10744004", "reactome": "R-SPO-3299680", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299683", "species_113529" ], "products": [ "species_113533", "species_1614617" ], "modifiers": [ [ "species_10744001", "catalyst" ] ], "additional_components": [ "Q9UQX0", "SPAC1486.01", "species_113527" ] }, "reaction_10733436": { "compartment": "compartment_17951", "id": "reaction_10733436", "reactome": "R-SPO-76031", "name": "2 H2O2 => O2 + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113575" ], "products": [ "species_141343", "species_113535" ], "modifiers": [ [ "species_10733433", "catalyst" ] ], "additional_components": [ "species_189444", "P55306", "SPCC757.07c", "species_113600" ] }, "reaction_10744568": { "compartment": "compartment_17927", "id": "reaction_10744568", "reactome": "R-SPO-3777112", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_163953" ], "products": [ "species_189481", "species_189461" ], "modifiers": [ [ "species_10744565", "catalyst" ] ], "additional_components": [ "species_442320", "P28758", "SPAC821.10c", "species_437295" ] }, "reaction_10745062": { "compartment": "compartment_17963", "id": "reaction_10745062", "reactome": "R-SPO-4837364", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745060" ], "products": [ "species_10744012" ], "modifiers": [], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "species_437295", "P28758", "SPAC821.10c", "species_442320", "species_437295" ] }, "reaction_10746853": { "compartment": "compartment_70101", "id": "reaction_10746853", "reactome": "R-SPO-5674385", "name": "p-T,Y MAPKs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741495" ], "products": [ "species_10744304" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10757290": { "compartment": "compartment_70101", "id": "reaction_10757290", "reactome": "R-SPO-9610166", "name": "p-T,Y MAPK dimers translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744304" ], "products": [ "species_10736632" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10739876": { "compartment": "compartment_70101", "id": "reaction_10739876", "reactome": "R-SPO-450517", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739853", "species_450523" ], "products": [ "species_10739855" ], "modifiers": [], "additional_components": [ "SPBC1718.07c", "P47979", "SPBC1718.07c" ] }, "reaction_10739870": { "compartment": "compartment_70101", "id": "reaction_10739870", "reactome": "R-SPO-450490", "name": "Protein Kinase B/Akt phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739855", "species_113592" ], "products": [ "species_29370", "species_10739867" ], "modifiers": [ [ "species_10736495", "catalyst" ] ], "additional_components": [ "P47979", "SPBC1718.07c", "P47979", "SPBC1718.07c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10738965": { "compartment": "compartment_876", "id": "reaction_10738965", "reactome": "R-SPO-427570", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10738962", "catalyst" ] ], "additional_components": [ "O59782", "SPCC320.05" ] }, "reaction_10738848": { "compartment": "compartment_171062", "id": "reaction_10738848", "reactome": "R-SPO-425983", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425978", "species_83910" ], "products": [ "species_70106", "species_425971" ], "modifiers": [ [ "species_10738845", "catalyst" ] ], "additional_components": [ "O13726", "SPAC15A10.06" ] }, "reaction_10738839": { "compartment": "compartment_172574", "id": "reaction_10738839", "reactome": "R-SPO-425965", "name": "SLC9A9 exchanges Na+ for H+ across the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83910", "species_425999" ], "products": [ "species_70106", "species_425977" ], "modifiers": [ [ "species_10738836", "catalyst" ] ], "additional_components": [ "SPAC15A10.06" ] }, "reaction_10746330": { "compartment": "compartment_70101", "id": "reaction_10746330", "reactome": "R-SPO-5627802", "name": "SLC26A4 transports I- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209785" ], "products": [ "species_209818" ], "modifiers": [ [ "species_10746327", "catalyst" ] ], "additional_components": [ "SPCC320.05" ] }, "reaction_10738878": { "compartment": "compartment_876", "id": "reaction_10738878", "reactome": "R-SPO-426130", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972" ], "products": [ "species_83910", "species_352022" ], "modifiers": [ [ "species_10738875", "catalyst" ] ], "additional_components": [ "SPBC18H10.16" ] }, "reaction_10754356": { "compartment": "compartment_70101", "id": "reaction_10754356", "reactome": "R-SPO-8855062", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162252", "species_71284" ], "products": [ "species_71285", "species_2162265" ], "modifiers": [ [ "species_10754353", "catalyst" ] ], "additional_components": [ "SPAC12B10.09" ] }, "reaction_10738984": { "compartment": "compartment_17938", "id": "reaction_10738984", "reactome": "R-SPO-428007", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427984", "species_428040" ], "products": [ "species_70106", "species_428003" ], "modifiers": [ [ "species_10738979", "catalyst" ] ], "additional_components": [ "CHEBI:90799", "CHEBI:32513", "CHEBI:32513", "CHEBI:46761", "SPBC13A2.04c" ] }, "reaction_10738956": { "compartment": "compartment_876", "id": "reaction_10738956", "reactome": "R-SPO-427555", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648", "species_351626" ], "products": [ "species_70106", "species_174375" ], "modifiers": [ [ "species_10738953", "catalyst" ] ], "additional_components": [ "O59782", "SPCC320.05" ] }, "reaction_10755472": { "compartment": "compartment_70101", "id": "reaction_10755472", "reactome": "R-SPO-8875623", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29404" ], "products": [ "species_113552", "species_113529" ], "modifiers": [ [ "species_10755469", "catalyst" ] ], "additional_components": [ "Q9P3T7", "SPAC328.09" ] }, "reaction_10755488": { "compartment": "compartment_70101", "id": "reaction_10755488", "reactome": "R-SPO-8875871", "name": "SLC26A11 transports SO4(2-) from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648" ], "products": [ "species_174375" ], "modifiers": [ [ "species_10755485", "catalyst" ] ], "additional_components": [ "SPAC869.05c" ] }, "reaction_10738819": { "compartment": "compartment_876", "id": "reaction_10738819", "reactome": "R-SPO-425822", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_425815" ], "products": [ "species_425810", "species_74112" ], "modifiers": [ [ "species_10738816", "catalyst" ] ], "additional_components": [ "SPAC3A12.06c" ] }, "reaction_10738974": { "compartment": "compartment_876", "id": "reaction_10738974", "reactome": "R-SPO-427666", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627", "species_188972" ], "products": [ "species_352022", "species_425425" ], "modifiers": [ [ "species_10738971", "catalyst" ] ], "additional_components": [ "O59782", "SPCC320.05" ] }, "reaction_10738873": { "compartment": "compartment_876", "id": "reaction_10738873", "reactome": "R-SPO-426086", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972", "species_74126" ], "products": [ "species_29804", "species_83910", "species_352022" ], "modifiers": [ [ "species_10738870", "catalyst" ] ], "additional_components": [ "O60146", "SPBC18H10.16" ] }, "reaction_10738853": { "compartment": "compartment_20699", "id": "reaction_10738853", "reactome": "R-SPO-426015", "name": "Na+/H+ exchanger transport (at trans-golgi membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425969", "species_83910" ], "products": [ "species_70106", "species_425958" ], "modifiers": [ [ "species_10738850", "catalyst" ] ], "additional_components": [ "SPAC15A10.06" ] }, "reaction_10753176": { "compartment": "compartment_70101", "id": "reaction_10753176", "reactome": "R-SPO-6809778", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809774", "species_29356" ], "products": [ "species_422529", "species_29372" ], "modifiers": [ [ "species_10753168", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10753572": { "compartment": "compartment_876", "id": "reaction_10753572", "reactome": "R-SPO-6814797", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2239407" ], "products": [ "species_6814794", "species_6814795" ], "modifiers": [ [ "species_10753569", "catalyst" ] ], "additional_components": [ "SPBC725.05c" ] }, "reaction_10753131": { "compartment": "compartment_70101", "id": "reaction_10753131", "reactome": "R-SPO-6809254", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753127", "species_10753125" ], "products": [ "species_10753129" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742441": { "compartment": "compartment_876", "id": "reaction_10742441", "reactome": "R-SPO-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10742438", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "O13819", "SPAC19A8.03" ] }, "reaction_10753468": { "compartment": "compartment_7660", "id": "reaction_10753468", "reactome": "R-SPO-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_6810408" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10753465", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14" ] }, "reaction_10742467": { "compartment": "compartment_12045", "id": "reaction_10742467", "reactome": "R-SPO-1676124", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806234", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10742464", "catalyst" ] ], "additional_components": [ "SPBC19F5.03" ] }, "reaction_10753148": { "compartment": "compartment_876", "id": "reaction_10753148", "reactome": "R-SPO-6809320", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10753145", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742498": { "compartment": "compartment_20699", "id": "reaction_10742498", "reactome": "R-SPO-1676185", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10742495", "catalyst" ] ], "additional_components": [ "Q9UT42", "SPAC343.19", "Q9USR3", "SPBC577.06c" ] }, "reaction_10742443": { "compartment": "compartment_172574", "id": "reaction_10742443", "reactome": "R-SPO-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_29370", "species_1806198" ], "modifiers": [ [ "species_10742410", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "species_113527" ] }, "reaction_10742425": { "compartment": "compartment_20699", "id": "reaction_10742425", "reactome": "R-SPO-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10742410", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "species_113527" ] }, "reaction_10753515": { "compartment": "compartment_12045", "id": "reaction_10753515", "reactome": "R-SPO-6814254", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6814253", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10753512", "catalyst" ] ], "additional_components": [ "SPCC4B3.04c" ] }, "reaction_10753151": { "compartment": "compartment_876", "id": "reaction_10753151", "reactome": "R-SPO-6809325", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10753145", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742449": { "compartment": "compartment_876", "id": "reaction_10742449", "reactome": "R-SPO-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742382": { "compartment": "compartment_12045", "id": "reaction_10742382", "reactome": "R-SPO-1675813", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_29370", "species_1806234" ], "modifiers": [ [ "species_10742379", "catalyst" ] ], "additional_components": [ "Q9UT42", "SPAC343.19", "Q9USR3", "SPBC577.06c" ] }, "reaction_10742353": { "compartment": "compartment_876", "id": "reaction_10742353", "reactome": "R-SPO-1675780", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_392417" ], "modifiers": [ [ "species_10742348", "catalyst" ] ], "additional_components": [ "SPAC343.19" ] }, "reaction_10742476": { "compartment": "compartment_171062", "id": "reaction_10742476", "reactome": "R-SPO-1676141", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10742451", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10753164": { "compartment": "compartment_171062", "id": "reaction_10753164", "reactome": "R-SPO-6809720", "name": "PI3P is dephosphorylated to PI by MTM1:MTMR12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10753155", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742473": { "compartment": "compartment_876", "id": "reaction_10742473", "reactome": "R-SPO-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_1806224" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742423": { "compartment": "compartment_876", "id": "reaction_10742423", "reactome": "R-SPO-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_29356" ], "products": [ "species_202247", "species_29372" ], "modifiers": [ [ "species_10742418", "catalyst" ] ], "additional_components": [ "SPBC577.13" ] }, "reaction_10753157": { "compartment": "compartment_70101", "id": "reaction_10753157", "reactome": "R-SPO-6809680", "name": "MTMR12 binds MTM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753153", "species_10742358" ], "products": [ "species_10753155" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742462": { "compartment": "compartment_20699", "id": "reaction_10742462", "reactome": "R-SPO-1676114", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806159", "species_29356" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10742459", "catalyst" ] ], "additional_components": [ "SPBC19F5.03" ] }, "reaction_10742488": { "compartment": "compartment_20699", "id": "reaction_10742488", "reactome": "R-SPO-1676152", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742486", "species_10742399" ], "products": [ "species_10742401" ], "modifiers": [], "additional_components": [ "SPAC22E12.16c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "P36579", "SPBC4F6.18c", "Q10366", "SPAC22E12.16c", "CHEBI:15996" ] }, "reaction_10742508": { "compartment": "compartment_20699", "id": "reaction_10742508", "reactome": "R-SPO-1676204", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806230", "species_29356" ], "products": [ "species_1806217", "species_29372" ], "modifiers": [ [ "species_10742503", "catalyst" ] ], "additional_components": [ "SPBC609.02" ] }, "reaction_10742454": { "compartment": "compartment_171062", "id": "reaction_10742454", "reactome": "R-SPO-1676105", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806205", "species_29356" ], "products": [ "species_1806259", "species_29372" ], "modifiers": [ [ "species_10742451", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742501": { "compartment": "compartment_876", "id": "reaction_10742501", "reactome": "R-SPO-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10742438", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "O13819", "SPAC19A8.03" ] }, "reaction_10753170": { "compartment": "compartment_70101", "id": "reaction_10753170", "reactome": "R-SPO-6809764", "name": "SBF1 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742360", "species_10753166" ], "products": [ "species_10753168" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742484": { "compartment": "compartment_876", "id": "reaction_10742484", "reactome": "R-SPO-1676149", "name": "PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_202247", "species_29356" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10736691", "catalyst" ] ], "additional_components": [ "SPBC609.02" ] }, "reaction_10742481": { "compartment": "compartment_876", "id": "reaction_10742481", "reactome": "R-SPO-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10742478", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14" ] }, "reaction_10742430": { "compartment": "compartment_876", "id": "reaction_10742430", "reactome": "R-SPO-1675988", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_392417" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10742387", "catalyst" ] ], "additional_components": [ "SPBC2G2.02" ] }, "reaction_10742320": { "compartment": "compartment_876", "id": "reaction_10742320", "reactome": "R-SPO-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_29370", "species_179838" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742404": { "compartment": "compartment_20699", "id": "reaction_10742404", "reactome": "R-SPO-1675883", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10742401", "catalyst" ] ], "additional_components": [ "P36579", "SPBC4F6.18c", "Q10366", "SPAC22E12.16c", "CHEBI:15996" ] }, "reaction_10736694": { "compartment": "compartment_70101", "id": "reaction_10736694", "reactome": "R-SPO-199456", "name": "PTEN dephosphorylates PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_29356" ], "products": [ "species_29372", "species_179856" ], "modifiers": [ [ "species_10736691", "catalyst" ] ], "additional_components": [ "SPBC609.02" ] }, "reaction_10742446": { "compartment": "compartment_172574", "id": "reaction_10742446", "reactome": "R-SPO-1676065", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806289" ], "products": [ "species_1806212", "species_29372" ], "modifiers": [ [ "species_10742366", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742392": { "compartment": "compartment_876", "id": "reaction_10742392", "reactome": "R-SPO-1675836", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10742387", "catalyst" ] ], "additional_components": [ "SPBC2G2.02" ] }, "reaction_10742372": { "compartment": "compartment_876", "id": "reaction_10742372", "reactome": "R-SPO-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_1806240" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742413": { "compartment": "compartment_171062", "id": "reaction_10742413", "reactome": "R-SPO-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10742410", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "species_113527" ] }, "reaction_10742369": { "compartment": "compartment_172574", "id": "reaction_10742369", "reactome": "R-SPO-1675795", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806198", "species_29356" ], "products": [ "species_1806195", "species_29372" ], "modifiers": [ [ "species_10742366", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10753143": { "compartment": "compartment_70101", "id": "reaction_10753143", "reactome": "R-SPO-6809309", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753127", "species_10742436" ], "products": [ "species_10753141" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10753161": { "compartment": "compartment_70101", "id": "reaction_10753161", "reactome": "R-SPO-6809707", "name": "MTMR12 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753153", "species_10742360" ], "products": [ "species_10753159" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742493": { "compartment": "compartment_876", "id": "reaction_10742493", "reactome": "R-SPO-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10742490", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "Q9USQ6", "SPBC577.13" ] }, "reaction_10742343": { "compartment": "compartment_876", "id": "reaction_10742343", "reactome": "R-SPO-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806240" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10742340", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14" ] }, "reaction_10753173": { "compartment": "compartment_70101", "id": "reaction_10753173", "reactome": "R-SPO-6809777", "name": "PI3P is dephosphorylated to PI by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10753168", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742470": { "compartment": "compartment_20699", "id": "reaction_10742470", "reactome": "R-SPO-1676133", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806217" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10742459", "catalyst" ] ], "additional_components": [ "SPBC19F5.03" ] }, "reaction_10742427": { "compartment": "compartment_171062", "id": "reaction_10742427", "reactome": "R-SPO-1675974", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806180" ], "modifiers": [ [ "species_10742348", "catalyst" ] ], "additional_components": [ "SPAC343.19" ] }, "reaction_10732994": { "compartment": "compartment_7660", "id": "reaction_10732994", "reactome": "R-SPO-75079", "name": "Formation of AT-AC C complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732990" ], "products": [ "species_10732982", "species_10732992" ], "modifiers": [], "additional_components": [ "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "Q9UUI3", "SPAC22F8.10c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q10178", "SPAC27F1.09c", "O74825", "SPBC337.14", "O94620", "SPBC1289.11", "Q9UUC6", "SPBC19C2.14", "Q02061", "SPAC23G3.01", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "Q9P7R6", "SPBC211.05", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05", "Q9UUC6", "SPBC19C2.14", "Q10163", "SPAC26A3.08", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "Q9USZ3", "SPBC11G11.06c", "O14036", "SPAC2C4.03c", "O74966", "SPBC4B4.05", "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "P36594", "SPBC28F2.12", "Q9UUI3", "SPAC22F8.10c", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q10178", "SPAC27F1.09c", "O94620", "SPBC1289.11", "Q02061", "SPAC23G3.01", "Q9UUC6", "SPBC19C2.14", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "P48011", "SPBC19C2.03", "Q9P7R6", "SPBC211.05", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05" ] }, "reaction_10732996": { "compartment": "compartment_7660", "id": "reaction_10732996", "reactome": "R-SPO-75082", "name": "ATAC spliceosome mediated Lariat formation,5' splice site cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732992" ], "products": [ "species_10732992" ], "modifiers": [], "additional_components": [ "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "P36594", "SPBC28F2.12", "Q9UUI3", "SPAC22F8.10c", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q10178", "SPAC27F1.09c", "O94620", "SPBC1289.11", "Q02061", "SPAC23G3.01", "Q9UUC6", "SPBC19C2.14", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "P48011", "SPBC19C2.03", "Q9P7R6", "SPBC211.05", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05", "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "P36594", "SPBC28F2.12", "Q9UUI3", "SPAC22F8.10c", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q10178", "SPAC27F1.09c", "O94620", "SPBC1289.11", "Q02061", "SPAC23G3.01", "Q9UUC6", "SPBC19C2.14", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "P48011", "SPBC19C2.03", "Q9P7R6", "SPBC211.05", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05" ] }, "reaction_10729563": { "compartment": "compartment_70101", "id": "reaction_10729563", "reactome": "R-SPO-69191", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729559", "species_10729541" ], "products": [ "species_10729561" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "SPBC11B10.09", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10735839": { "compartment": "compartment_7660", "id": "reaction_10735839", "reactome": "R-SPO-188350", "name": "CAK-mediated phosphorylation of Cyclin E:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10729567" ], "products": [ "species_113582", "species_10729404" ], "modifiers": [ [ "species_10732457", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07" ] }, "reaction_10729580": { "compartment": "compartment_7660", "id": "reaction_10729580", "reactome": "R-SPO-69199", "name": "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729572", "species_113518" ], "products": [ "species_113550", "species_10729567" ], "modifiers": [ [ "species_10729577", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "SPAC24H6.05" ] }, "reaction_10734745": { "compartment": "compartment_13231", "id": "reaction_10734745", "reactome": "R-SPO-157906", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729561" ], "products": [ "species_10729567" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10747656": { "compartment": "compartment_7660", "id": "reaction_10747656", "reactome": "R-SPO-5685230", "name": "CHEK1 phosphorylates RAD51", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747651" ], "products": [ "species_113582", "species_10747654" ], "modifiers": [ [ "species_10729605", "catalyst" ] ], "additional_components": [ "SPAC644.14c", "SPAC644.14c", "O13945", "SPAC23H4.02", "O74536", "SPCC74.03c" ] }, "reaction_10747710": { "compartment": "compartment_7660", "id": "reaction_10747710", "reactome": "R-SPO-5687464", "name": "MRN and RBBP8 resect DNA DSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747703" ], "products": [ "species_10747707", "species_30555" ], "modifiers": [ [ "species_10747703", "catalyst" ] ], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10733424": { "compartment": "compartment_7660", "id": "reaction_10733424", "reactome": "R-SPO-75998", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733420" ], "products": [ "species_10733422" ], "modifiers": [], "additional_components": [ "SPAC30D11.10", "P36592", "SPAC30D11.10" ] }, "reaction_10747593": { "compartment": "compartment_7660", "id": "reaction_10747593", "reactome": "R-SPO-5684140", "name": "ATM phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747581" ], "products": [ "species_113582", "species_10747590" ], "modifiers": [ [ "species_10747581", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747723": { "compartment": "compartment_7660", "id": "reaction_10747723", "reactome": "R-SPO-5687664", "name": "FEN1 cleaves displaced ssDNA flaps during MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747716" ], "products": [ "species_10747720", "species_10729528", "species_68454" ], "modifiers": [ [ "species_10747716", "catalyst" ] ], "additional_components": [ "P39750", "SPAC3G6.06c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "SPAC3G6.06c", "P39750", "SPAC3G6.06c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747676": { "compartment": "compartment_7660", "id": "reaction_10747676", "reactome": "R-SPO-5686430", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747661", "species_10747668" ], "products": [ "species_10747674" ], "modifiers": [], "additional_components": [ "SPAPB1E7.06c", "SPCC4G3.05c", "Q9C103", "SPAPB1E7.06c", "P87231", "SPCC4G3.05c" ] }, "reaction_10747584": { "compartment": "compartment_7660", "id": "reaction_10747584", "reactome": "R-SPO-5684096", "name": "CDK2 phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747575" ], "products": [ "species_113582", "species_10728937", "species_10747581" ], "modifiers": [ [ "species_10747575", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "P36630", "SPAPB2B4.03", "Q09683", "SPAC13C5.07", "P10815", "SPBC582.03", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "P36630", "SPAPB2B4.03", "Q09683", "SPAC13C5.07", "P10815", "SPBC582.03", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10756974": { "compartment": "compartment_70101", "id": "reaction_10756974", "reactome": "R-SPO-9018877", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023708", "species_29356" ], "products": [ "species_9023712" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756059": { "compartment": "compartment_7660", "id": "reaction_10756059", "reactome": "R-SPO-8943007", "name": "SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756041", "species_10746403", "species_10733964", "species_10756047" ], "products": [ "species_10756049" ], "modifiers": [], "additional_components": [ "SPAC144.05", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9UTL9", "SPAC144.05", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10756057": { "compartment": "compartment_7660", "id": "reaction_10756057", "reactome": "R-SPO-8943003", "name": "SHPRH polyubiquitinates monoubiquitinated PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756049", "species_10756047" ], "products": [ "species_10756041", "species_10756054", "species_10746403", "species_10747373" ], "modifiers": [ [ "species_10756049", "catalyst" ] ], "additional_components": [ "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9UTL9", "SPAC144.05", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "SPAC144.05", "Q03392", "SPBC16D10.09", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9UTL9", "SPAC144.05", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10756390": { "compartment": "compartment_17947", "id": "reaction_10756390", "reactome": "R-SPO-8953946", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756378" ], "products": [ "species_10756387", "species_10741537" ], "modifiers": [ [ "species_10756378", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "O60065", "SPBC13G1.03c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O14136", "SPAC3C7.10", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH07", "SPAC1805.12c", "O60065", "SPBC13G1.03c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O14136", "SPAC3C7.10", "P0CH06", "SPAC11G7.04" ] }, "reaction_10756380": { "compartment": "compartment_17947", "id": "reaction_10756380", "reactome": "R-SPO-8953917", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756372", "species_10756376" ], "products": [ "species_10756378" ], "modifiers": [], "additional_components": [ "O60065", "SPBC13G1.03c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "O60065", "SPBC13G1.03c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O14136", "SPAC3C7.10", "P0CH06", "SPAC11G7.04" ] }, "reaction_10733705": { "compartment": "compartment_7660", "id": "reaction_10733705", "reactome": "R-SPO-109636", "name": "Recognition and Binding of Core Promoter Elements by TFIID", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109627", "species_10732699" ], "products": [ "species_10732998" ], "modifiers": [], "additional_components": [ "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c" ] }, "reaction_10733707": { "compartment": "compartment_7660", "id": "reaction_10733707", "reactome": "R-SPO-109637", "name": "Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732619", "species_10732998", "species_10732624" ], "products": [ "species_10733000" ], "modifiers": [], "additional_components": [ "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "SPAC16E8.16", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c" ] }, "reaction_10733709": { "compartment": "compartment_7660", "id": "reaction_10733709", "reactome": "R-SPO-109638", "name": "Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733000", "species_10730708" ], "products": [ "species_10733002" ], "modifiers": [], "additional_components": [ "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c" ] }, "reaction_10733006": { "compartment": "compartment_7660", "id": "reaction_10733006", "reactome": "R-SPO-75095", "name": "Binding of TFIIE to the growing preinitiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732711", "species_10733002" ], "products": [ "species_10733004" ], "modifiers": [], "additional_components": [ "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c" ] }, "reaction_10733711": { "compartment": "compartment_7660", "id": "reaction_10733711", "reactome": "R-SPO-109639", "name": "Formation of the closed pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733004", "species_10732494" ], "products": [ "species_10733340" ], "modifiers": [], "additional_components": [ "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750331": { "compartment": "compartment_5460", "id": "reaction_10750331", "reactome": "R-SPO-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10750328", "catalyst" ] ], "additional_components": [ "Q9P7Y7", "SPAPYUG7.05" ] }, "reaction_10729991": { "compartment": "compartment_70101", "id": "reaction_10729991", "reactome": "R-SPO-70606", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_31633" ], "products": [ "species_29370", "species_29472", "species_29372" ], "modifiers": [ [ "species_10729988", "catalyst" ] ], "additional_components": [ "Q09179", "SPAC23H4.06" ] }, "reaction_10730012": { "compartment": "compartment_5460", "id": "reaction_10730012", "reactome": "R-SPO-70654", "name": "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113585" ], "products": [ "species_31339", "species_113552" ], "modifiers": [ [ "species_10730009", "catalyst" ] ], "additional_components": [ "Q9P7L5", "SPBC21C3.08c" ] }, "reaction_10729993": { "compartment": "compartment_5460", "id": "reaction_10729993", "reactome": "R-SPO-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113587" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10729968", "catalyst" ] ], "additional_components": [ "O94320", "SPBC725.01" ] }, "reaction_10730022": { "compartment": "compartment_5460", "id": "reaction_10730022", "reactome": "R-SPO-70664", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10730019", "catalyst" ] ], "additional_components": [ "Q9P7Y7", "SPAPYUG7.05" ] }, "reaction_10740180": { "compartment": "compartment_5460", "id": "reaction_10740180", "reactome": "R-SPO-508040", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_113552", "species_113529", "species_113593" ], "products": [ "species_31339", "species_113548", "species_113563", "species_113581" ], "modifiers": [ [ "species_10740177", "catalyst" ] ], "additional_components": [ "Q9UT44", "SPAC821.11" ] }, "reaction_10740380": { "compartment": "compartment_70101", "id": "reaction_10740380", "reactome": "R-SPO-893616", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29398" ], "products": [ "species_893598", "species_29432" ], "modifiers": [ [ "species_10740371", "catalyst" ] ], "additional_components": [ "O14209", "SPAC6B12.04c" ] }, "reaction_10750338": { "compartment": "compartment_70101", "id": "reaction_10750338", "reactome": "R-SPO-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_35305" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10750335", "catalyst" ] ], "additional_components": [ "Q9P7Y7", "SPAPYUG7.05" ] }, "reaction_10734483": { "compartment": "compartment_17906", "id": "reaction_10734483", "reactome": "R-SPO-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734481" ], "products": [ "species_10734479" ], "modifiers": [], "additional_components": [ "SPCC191.07", "SPCC191.07" ] }, "reaction_10752635": { "compartment": "compartment_984", "id": "reaction_10752635", "reactome": "R-SPO-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737741" ], "products": [ "species_10752522" ], "modifiers": [], "additional_components": [ "SPAC57A10.09c", "SPAC57A10.09c" ] }, "reaction_10745096": { "compartment": "compartment_7660", "id": "reaction_10745096", "reactome": "R-SPO-5082384", "name": "HSP70:DNAJB1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744254", "species_10744224" ], "products": [ "species_10744256" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O59855", "SPCC1739.13", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06" ] }, "reaction_10744320": { "compartment": "compartment_7660", "id": "reaction_10744320", "reactome": "R-SPO-3371582", "name": "HSBP1 binds HSF1 trimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744252", "species_10744316" ], "products": [ "species_10744318" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14330", "SPBC16E9.15", "O14330", "SPBC16E9.15", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10757482": { "compartment": "compartment_70101", "id": "reaction_10757482", "reactome": "R-SPO-9635743", "name": "PTPN7 binds p-T,Y-MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757459", "species_10744304" ], "products": [ "species_10757461" ], "modifiers": [], "additional_components": [ "P27574", "SPAC26F1.10c", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01" ] }, "reaction_10746868": { "compartment": "compartment_70101", "id": "reaction_10746868", "reactome": "R-SPO-5674496", "name": "Activated MAPKs phosphorylate MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746838", "species_113592" ], "products": [ "species_29370", "species_10746865" ], "modifiers": [ [ "species_10746855", "catalyst" ] ], "additional_components": [ "P10506", "SPAC1D4.13", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10746885": { "compartment": "compartment_7660", "id": "reaction_10746885", "reactome": "R-SPO-5675373", "name": "Nuclear DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746859", "species_29356" ], "products": [ "species_10746870", "species_113550" ], "modifiers": [ [ "species_10746872", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPBC1685.01" ] }, "reaction_10757480": { "compartment": "compartment_70101", "id": "reaction_10757480", "reactome": "R-SPO-9635739", "name": "PTPN7 dephosphorylates p-T,Y-MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757461", "species_29356" ], "products": [ "species_10757477", "species_29372" ], "modifiers": [ [ "species_10757461", "catalyst" ] ], "additional_components": [ "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01", "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01", "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01" ] }, "reaction_10746906": { "compartment": "compartment_70101", "id": "reaction_10746906", "reactome": "R-SPO-5675376", "name": "Cytosolic DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10746855" ], "products": [ "species_10746891", "species_29372" ], "modifiers": [ [ "species_10746893", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPBC1685.01" ] }, "reaction_10745486": { "compartment": "compartment_7660", "id": "reaction_10745486", "reactome": "R-SPO-5228523", "name": "RANBP2 SUMOylates MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743716", "species_10743647" ], "products": [ "species_10743639", "species_10743724" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPCC285.17", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "O74503", "SPCC285.17", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10743731": { "compartment": "compartment_7660", "id": "reaction_10743731", "reactome": "R-SPO-3000434", "name": "PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743716", "species_10743647" ], "products": [ "species_10743639", "species_10743724" ], "modifiers": [ [ "species_10743726", "catalyst" ] ], "additional_components": [ "SPCC285.17", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "O74503", "SPCC285.17", "SPAC1687.05" ] }, "reaction_10751267": { "compartment": "compartment_876", "id": "reaction_10751267", "reactome": "R-SPO-6797630", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_417891", "species_109276" ], "products": [ "species_6797635", "species_109277" ], "modifiers": [ [ "species_10751264", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10757778": { "compartment": "compartment_70101", "id": "reaction_10757778", "reactome": "R-SPO-9668419", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738115", "species_113592", "species_29356" ], "products": [ "species_10738111", "species_29370", "species_29372" ], "modifiers": [ [ "species_10757769", "catalyst" ] ], "additional_components": [ "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c" ] }, "reaction_10743751": { "compartment": "compartment_13231", "id": "reaction_10743751", "reactome": "R-SPO-3000449", "name": "UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743738", "species_10743647" ], "products": [ "species_10743639", "species_10743748" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "P41391", "SPAC22E12.07", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P41391", "SPAC22E12.07", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10757349": { "compartment": "compartment_1598585", "id": "reaction_10757349", "reactome": "R-SPO-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737260", "species_29438" ], "products": [ "species_10745968", "species_29420" ], "modifiers": [ [ "species_10757346", "catalyst" ] ], "additional_components": [ "species_29420", "P28748", "SPBC1289.03c", "P28748", "SPBC1289.03c", "species_29438", "SPBC557.03c" ] }, "reaction_10757341": { "compartment": "compartment_13231", "id": "reaction_10757341", "reactome": "R-SPO-9624798", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737539", "species_10757337" ], "products": [ "species_10757339" ], "modifiers": [], "additional_components": [ "SPAC1B1.03c", "SPBC16G5.18", "Q09195", "SPBC16G5.18", "O13864", "SPAC1B1.03c" ] }, "reaction_10757773": { "compartment": "compartment_70101", "id": "reaction_10757773", "reactome": "R-SPO-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757769", "species_10740625" ], "products": [ "species_10757771" ], "modifiers": [], "additional_components": [ "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "SPAC2G11.06", "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "Q09803", "SPAC2G11.06", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c" ] }, "reaction_10743193": { "compartment": "compartment_70101", "id": "reaction_10743193", "reactome": "R-SPO-2467775", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743182" ], "products": [ "species_10743190" ], "modifiers": [ [ "species_10743182", "catalyst" ] ], "additional_components": [ "SPCC5E4.04", "P18296", "SPCC5E4.04", "SPCC5E4.04" ] }, "reaction_10757442": { "compartment": "compartment_70101", "id": "reaction_10757442", "reactome": "R-SPO-9634169", "name": "POM121 and NDC1 bind the Nup93 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757438", "species_10757311", "species_10733090", "species_10757436" ], "products": [ "species_10757440" ], "modifiers": [], "additional_components": [ "SPAP27G11.10c", "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "Q09904", "SPAC30D11.04c", "O36030", "SPAC4F10.18", "Q10331", "SPBC428.01c", "Q9UTK4", "SPAC1486.05", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "Q9UUE5", "SPBC17G9.04c", "O43044", "SPBC3B9.16c", "SPAC1786.03", "O94418", "SPCC1620.11", "O13838", "SPAC19E9.01c", "P78847", "SPCC290.03c", "Q9URX8", "SPAC890.06", "O94418", "SPCC1620.11", "Q09904", "SPAC30D11.04c", "Q10331", "SPBC428.01c", "P78847", "SPCC290.03c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q9UUE5", "SPBC17G9.04c", "Q9P7M8", "SPAP27G11.10c", "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "O13961", "SPAC1786.03", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "O43044", "SPBC3B9.16c" ] }, "reaction_10757353": { "compartment": "compartment_70101", "id": "reaction_10757353", "reactome": "R-SPO-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9624879", "species_10745968" ], "products": [ "species_10757351" ], "modifiers": [], "additional_components": [ "P28748", "SPBC1289.03c", "species_29438", "P28748", "SPBC1289.03c", "species_29438" ] }, "reaction_10743226": { "compartment": "compartment_70101", "id": "reaction_10743226", "reactome": "R-SPO-2467798", "name": "PTTG1 (Securin) sequesters ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743182", "species_10743222" ], "products": [ "species_10743224" ], "modifiers": [], "additional_components": [ "SPCC5E4.04", "SPBC14C8.01c", "P18296", "SPCC5E4.04", "P21135", "SPBC14C8.01c" ] }, "reaction_10757356": { "compartment": "compartment_70101", "id": "reaction_10757356", "reactome": "R-SPO-9624893", "name": "RAN stimulates fusion of nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757351", "species_29356" ], "products": [ "species_10737260", "species_29372", "species_9624890" ], "modifiers": [ [ "species_10743748", "catalyst" ] ], "additional_components": [ "P28748", "SPBC1289.03c", "species_29438", "species_29420", "P28748", "SPBC1289.03c", "O13351", "SPBC365.06", "P41391", "SPAC22E12.07" ] }, "reaction_10757775": { "compartment": "compartment_70101", "id": "reaction_10757775", "reactome": "R-SPO-9668405", "name": "SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757757", "species_10757767" ], "products": [ "species_10757769" ], "modifiers": [], "additional_components": [ "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c" ] }, "reaction_10757313": { "compartment": "compartment_70101", "id": "reaction_10757313", "reactome": "R-SPO-9618378", "name": "POM121 binds the Nup107-Nup160 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757309", "species_10733083" ], "products": [ "species_10757311" ], "modifiers": [], "additional_components": [ "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "O36030", "SPAC4F10.18", "Q10331", "SPBC428.01c", "Q9UTK4", "SPAC1486.05", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "Q9UUE5", "SPBC17G9.04c", "O43044", "SPBC3B9.16c", "SPAC30D11.04c", "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "Q09904", "SPAC30D11.04c", "O36030", "SPAC4F10.18", "Q10331", "SPBC428.01c", "Q9UTK4", "SPAC1486.05", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "Q9UUE5", "SPBC17G9.04c", "O43044", "SPBC3B9.16c" ] }, "reaction_10758064": { "compartment": "compartment_70101", "id": "reaction_10758064", "reactome": "R-SPO-9748957", "name": "GMPS dimer transforms 6TXMP to 6TGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29356", "species_9748959" ], "products": [ "species_70106", "species_9748970", "species_29404", "species_111294", "species_76577" ], "modifiers": [ [ "species_10758061", "catalyst" ] ], "additional_components": [ "Q9P772", "SPBC2F12.14c" ] }, "reaction_10758081": { "compartment": "compartment_70101", "id": "reaction_10758081", "reactome": "R-SPO-9750546", "name": "ABCC4 transports TPMP substrates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750587", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750548", "species_29372" ], "modifiers": [ [ "species_10741716", "catalyst" ] ], "additional_components": [ "species_9748992", "species_9748970", "pubchem.compound:3037883", "CHEBI:80613", "pubchem.compound:3037883", "CHEBI:2332", "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10758059": { "compartment": "compartment_70101", "id": "reaction_10758059", "reactome": "R-SPO-9748949", "name": "GUK1 phosphorylates 6TGMP to 6TGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748970", "species_113592" ], "products": [ "species_29370", "species_9748960" ], "modifiers": [ [ "species_10732507", "catalyst" ] ], "additional_components": [ "SPBC1198.05" ] }, "reaction_10758057": { "compartment": "compartment_70101", "id": "reaction_10758057", "reactome": "R-SPO-9748945", "name": "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748992", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_9748959" ], "modifiers": [ [ "species_10732525", "catalyst" ] ], "additional_components": [ "O14344", "SPBC2F12.14c" ] }, "reaction_10758087": { "compartment": "compartment_70101", "id": "reaction_10758087", "reactome": "R-SPO-9753278", "name": "ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10741710", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "CHEBI:132962", "CHEBI:32636", "CHEBI:32635", "Q10185", "SPAC3F10.11c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10758096": { "compartment": "compartment_70101", "id": "reaction_10758096", "reactome": "R-SPO-9753632", "name": "CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753680", "species_29356" ], "products": [ "species_9753653", "species_29424" ], "modifiers": [ [ "species_10741586", "catalyst" ] ], "additional_components": [ "Q9P6I2", "SPBC1198.08", "species_113527" ] }, "reaction_10758070": { "compartment": "compartment_70101", "id": "reaction_10758070", "reactome": "R-SPO-9748999", "name": "NME1:2 hexamer phosphorylates 6TGDP to 6TGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9748960" ], "products": [ "species_29370", "species_9748947" ], "modifiers": [ [ "species_10740061", "catalyst" ] ], "additional_components": [ "P49740", "SPAC806.07" ] }, "reaction_10758089": { "compartment": "compartment_70101", "id": "reaction_10758089", "reactome": "R-SPO-9753283", "name": "ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10741716", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "CHEBI:132962", "CHEBI:32636", "CHEBI:32635", "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10758068": { "compartment": "compartment_70101", "id": "reaction_10758068", "reactome": "R-SPO-9748969", "name": "NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9749033" ], "products": [ "species_29370", "species_9749032" ], "modifiers": [ [ "species_10740061", "catalyst" ] ], "additional_components": [ "P49740", "SPAC806.07" ] }, "reaction_10758084": { "compartment": "compartment_70101", "id": "reaction_10758084", "reactome": "R-SPO-9750656", "name": "ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750692", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750678", "species_29372" ], "modifiers": [ [ "species_10741710", "catalyst" ] ], "additional_components": [ "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "CHEBI:176960", "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "CHEBI:176960", "Q10185", "SPAC3F10.11c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10742965": { "compartment": "compartment_70101", "id": "reaction_10742965", "reactome": "R-SPO-2162078", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161185", "species_29360" ], "products": [ "species_70106", "species_73473", "species_2162081" ], "modifiers": [ [ "species_10730504", "catalyst" ] ], "additional_components": [ "species_442320", "P78870", "SPCC13B11.04c", "O74540", "SPCC13B11.04c" ] }, "reaction_10758066": { "compartment": "compartment_70101", "id": "reaction_10758066", "reactome": "R-SPO-9748963", "name": "GUK1 phosphorylates 6TdGMP to 6TdGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9749031", "species_113592" ], "products": [ "species_29370", "species_9749033" ], "modifiers": [ [ "species_10732507", "catalyst" ] ], "additional_components": [ "SPBC1198.05" ] }, "reaction_10758098": { "compartment": "compartment_876", "id": "reaction_10758098", "reactome": "R-SPO-9753634", "name": "GGT dimers hydrolyse APAP-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753685", "species_29356" ], "products": [ "species_9753680", "species_29404" ], "modifiers": [ [ "species_10745932", "catalyst" ] ], "additional_components": [ "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10758094": { "compartment": "compartment_70101", "id": "reaction_10758094", "reactome": "R-SPO-9753284", "name": "ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9753629", "species_29356" ], "products": [ "species_29370", "species_9753624", "species_29372" ], "modifiers": [ [ "species_10758091", "catalyst" ] ], "additional_components": [ "CHEBI:133438", "species_9753653", "CHEBI:133066", "CHEBI:133435", "Q92337", "SPAC9E9.12c", "Q10185", "SPAC3F10.11c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10735847": { "compartment": "compartment_5460", "id": "reaction_10735847", "reactome": "R-SPO-188467", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_188458" ], "products": [ "species_188451", "species_31649" ], "modifiers": [ [ "species_10735844", "catalyst" ] ], "additional_components": [ "SPCC1223.03c" ] }, "reaction_10738355": { "compartment": "compartment_70101", "id": "reaction_10738355", "reactome": "R-SPO-389788", "name": "Activation of PAKs by RAC1 and CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738349", "species_10738231" ], "products": [ "species_10738353", "species_10738351" ], "modifiers": [], "additional_components": [ "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c" ] }, "reaction_10741676": { "compartment": "compartment_70101", "id": "reaction_10741676", "reactome": "R-SPO-1358791", "name": "Phosphorylation of USP8 by P-AKT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741666" ], "products": [ "species_29370", "species_10741674" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "O60079", "SPCC1494.05c", "Q9USM5", "SPCC16A11.12c", "O60079", "SPCC1494.05c", "Q9USM5", "SPCC16A11.12c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10757404": { "compartment": "compartment_70101", "id": "reaction_10757404", "reactome": "R-SPO-9627369", "name": "SEPT4 binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757400", "species_10745678" ], "products": [ "species_10757402" ], "modifiers": [], "additional_components": [ "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11", "SPCC962.02c", "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "O14064", "SPCC962.02c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11" ] }, "reaction_10732312": { "compartment": "compartment_70101", "id": "reaction_10732312", "reactome": "R-SPO-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73578" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10732309", "catalyst" ] ], "additional_components": [ "O94413", "SPCC1620.06c", "P41831", "SPCC1620.06c", "P87171", "SPCC1620.06c" ] }, "reaction_10735815": { "compartment": "compartment_70101", "id": "reaction_10735815", "reactome": "R-SPO-177784", "name": "ribose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10730283", "catalyst" ] ], "additional_components": [ "SPAC144.12" ] }, "reaction_10730278": { "compartment": "compartment_70101", "id": "reaction_10730278", "reactome": "R-SPO-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10730275", "catalyst" ] ], "additional_components": [ "O14105", "SPAC31G5.05c", "species_113531" ] }, "reaction_10750445": { "compartment": "compartment_70101", "id": "reaction_10750445", "reactome": "R-SPO-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10729638", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10734989": { "compartment": "compartment_70101", "id": "reaction_10734989", "reactome": "R-SPO-163764", "name": "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29878", "species_29512" ], "products": [ "species_29578", "species_29882" ], "modifiers": [ [ "species_10730293", "catalyst" ] ], "additional_components": [ "O42700", "SPCC1020.06c" ] }, "reaction_10736696": { "compartment": "compartment_70101", "id": "reaction_10736696", "reactome": "R-SPO-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10730275", "catalyst" ] ], "additional_components": [ "O14105", "SPAC31G5.05c", "species_113531" ] }, "reaction_10730248": { "compartment": "compartment_70101", "id": "reaction_10730248", "reactome": "R-SPO-71296", "name": "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31467", "species_29356" ], "products": [ "species_29996" ], "modifiers": [ [ "species_10730245", "catalyst" ] ], "additional_components": [ "SPCC16C4.10" ] }, "reaction_10730258": { "compartment": "compartment_70101", "id": "reaction_10730258", "reactome": "R-SPO-71299", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_29996" ], "products": [ "species_70106", "species_29732", "species_29364", "species_113528" ], "modifiers": [ [ "species_10730255", "catalyst" ] ], "additional_components": [ "P78812", "SPBC660.16" ] }, "reaction_10729691": { "compartment": "compartment_70101", "id": "reaction_10729691", "reactome": "R-SPO-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_30537" ], "products": [ "species_70106", "species_29364", "species_31467" ], "modifiers": [ [ "species_10729688", "catalyst" ] ], "additional_components": [ "species_29366", "O00091", "SPAC3A12.18" ] }, "reaction_10756527": { "compartment": "compartment_70101", "id": "reaction_10756527", "reactome": "R-SPO-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10729638", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10756433": { "compartment": "compartment_70101", "id": "reaction_10756433", "reactome": "R-SPO-8955844", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8955853" ], "products": [ "species_29370", "species_73578" ], "modifiers": [ [ "species_10756430", "catalyst" ] ], "additional_components": [ "SPBC16G5.02c" ] }, "reaction_10734063": { "compartment": "compartment_70101", "id": "reaction_10734063", "reactome": "R-SPO-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10732305", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_29372", "catalyst" ] ], "additional_components": [ "O94413", "SPCC1620.06c", "P41831", "SPCC1620.06c", "P87171", "SPCC1620.06c" ] }, "reaction_10743558": { "compartment": "compartment_70101", "id": "reaction_10743558", "reactome": "R-SPO-2730872", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742830", "species_74016", "species_10737034" ], "products": [ "species_10743532" ], "modifiers": [], "additional_components": [ "species_442320", "Q9UU93", "SPCC830.06", "Q12705", "SPBP4H10.04", "CHEBI:29034", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q12705", "SPBP4H10.04", "CHEBI:29034" ] }, "reaction_10744811": { "compartment": "compartment_70101", "id": "reaction_10744811", "reactome": "R-SPO-4551465", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744805" ], "products": [ "species_10744809" ], "modifiers": [], "additional_components": [ "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q12705", "SPBP4H10.04", "CHEBI:29034", "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "Q12705", "SPBP4H10.04", "O14008", "SPAC29A4.05", "CHEBI:29034" ] }, "reaction_10743992": { "compartment": "compartment_20699", "id": "reaction_10743992", "reactome": "R-SPO-3247836", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743986" ], "products": [ "species_10743990" ], "modifiers": [], "additional_components": [ "Q9UTI5", "SPAC15E1.06", "O74552", "SPCC777.13", "O94291", "SPBC887.06c", "Q10243", "SPAC4G9.13c", "Q9UTI5", "SPAC15E1.06", "O74552", "SPCC777.13", "O94291", "SPBC887.06c", "Q10243", "SPAC4G9.13c" ] }, "reaction_10750278": { "compartment": "compartment_7660", "id": "reaction_10750278", "reactome": "R-SPO-6782211", "name": "DNA polymerases delta, epsilon or kappa bind the TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749283", "species_10749285", "species_10750264", "species_10729448" ], "products": [ "species_10750276" ], "modifiers": [], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "O74944", "SPCC553.07c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P36617", "SPCC970.01", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "P87324", "SPAC27E2.05", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P36617", "SPCC970.01", "P87123", "SPAC3A12.07", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94508", "SPBC646.02", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750246": { "compartment": "compartment_7660", "id": "reaction_10750246", "reactome": "R-SPO-6782131", "name": "ERCC2-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10750232" ], "products": [ "species_113582", "species_10750243", "species_113550" ], "modifiers": [ [ "species_10750232", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750267": { "compartment": "compartment_7660", "id": "reaction_10750267", "reactome": "R-SPO-6782204", "name": "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750260" ], "products": [ "species_10750264" ], "modifiers": [ [ "species_10750260", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P36617", "SPCC970.01", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P36617", "SPCC970.01", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P36617", "SPCC970.01", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750258": { "compartment": "compartment_7660", "id": "reaction_10750258", "reactome": "R-SPO-6782138", "name": "ERCC5 and RPA bind TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747765", "species_10750254", "species_10729504" ], "products": [ "species_10750256" ], "modifiers": [], "additional_components": [ "SPBC3E7.08c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750262": { "compartment": "compartment_7660", "id": "reaction_10750262", "reactome": "R-SPO-6782141", "name": "Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750256", "species_10733829" ], "products": [ "species_10750260" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P36617", "SPCC970.01", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10757829": { "compartment": "compartment_7660", "id": "reaction_10757829", "reactome": "R-SPO-9684118", "name": "ERCC3-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10750243" ], "products": [ "species_113582", "species_10750254", "species_113550" ], "modifiers": [ [ "species_10750243", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750281": { "compartment": "compartment_7660", "id": "reaction_10750281", "reactome": "R-SPO-6782224", "name": "3' incision by ERCC5 (XPG) in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750276" ], "products": [ "species_10750269", "species_10747765", "species_10747770", "species_10733829" ], "modifiers": [ [ "species_10750276", "catalyst" ] ], "additional_components": [ "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "P87324", "SPAC27E2.05", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P36617", "SPCC970.01", "P87123", "SPAC3A12.07", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94508", "SPBC646.02", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "SPBC3E7.08c", "SPBC649.03", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "P87324", "SPAC27E2.05", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P36617", "SPCC970.01", "P87123", "SPAC3A12.07", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94508", "SPBC646.02", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c" ] }, "reaction_10740162": { "compartment": "compartment_876", "id": "reaction_10740162", "reactome": "R-SPO-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10740159", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10739398": { "compartment": "compartment_876", "id": "reaction_10739398", "reactome": "R-SPO-444160", "name": "VMAT1/2 can mediate the transport of biogenic amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444154" ], "products": [ "species_444152" ], "modifiers": [ [ "species_10739395", "catalyst" ] ], "additional_components": [ "CHEBI:18295", "species_351601", "CHEBI:18357", "CHEBI:28918", "species_209914", "CHEBI:18295", "species_351601", "CHEBI:18357", "CHEBI:28918", "species_209914", "O74852", "SPCC18.02" ] }, "reaction_10739315": { "compartment": "compartment_876", "id": "reaction_10739315", "reactome": "R-SPO-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_446589", "species_351626" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10739312", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "Q9USK3", "SPCC4B3.13", "Q10085", "SPCC4B3.13", "Q9UT92", "SPCC4B3.13" ] }, "reaction_10740155": { "compartment": "compartment_876", "id": "reaction_10740155", "reactome": "R-SPO-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10756479": { "compartment": "compartment_70101", "id": "reaction_10756479", "reactome": "R-SPO-8959798", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29418" ], "products": [ "species_266099" ], "modifiers": [ [ "species_10756476", "catalyst" ] ], "additional_components": [ "SPAC23C11.14" ] }, "reaction_10740289": { "compartment": "compartment_20699", "id": "reaction_10740289", "reactome": "R-SPO-742345", "name": "SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742368" ], "products": [ "species_205683" ], "modifiers": [ [ "species_10740286", "catalyst" ] ], "additional_components": [ "SPAC22F8.04" ] }, "reaction_10739323": { "compartment": "compartment_876", "id": "reaction_10739323", "reactome": "R-SPO-435366", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_158417" ], "modifiers": [ [ "species_10739320", "catalyst" ] ], "additional_components": [ "SPAC23C11.14" ] }, "reaction_10740865": { "compartment": "compartment_876", "id": "reaction_10740865", "reactome": "R-SPO-939763", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_947594", "species_113592", "species_29356" ], "products": [ "species_29370", "species_947588", "species_29372" ], "modifiers": [ [ "species_10740862", "catalyst" ] ], "additional_components": [ "species_1500646", "species_1500581", "species_1500646", "species_1500581", "Q10309", "SPAC6C3.06c", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O94296", "SPBC887.12", "Q09891", "SPAC24B11.12c" ] }, "reaction_10740157": { "compartment": "compartment_876", "id": "reaction_10740157", "reactome": "R-SPO-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10747160": { "compartment": "compartment_70101", "id": "reaction_10747160", "reactome": "R-SPO-5678863", "name": "CFTR transports Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_352022", "species_29356" ], "products": [ "species_29370", "species_188972", "species_29372" ], "modifiers": [ [ "species_10738217", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10745661": { "compartment": "compartment_70101", "id": "reaction_10745661", "reactome": "R-SPO-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10745658", "catalyst" ] ], "additional_components": [ "SPBC25H2.08c" ] }, "reaction_10745601": { "compartment": "compartment_70101", "id": "reaction_10745601", "reactome": "R-SPO-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5252122" ], "products": [ "species_29370", "species_5252016", "species_29372" ], "modifiers": [ [ "species_10745598", "catalyst" ] ], "additional_components": [ "O74431", "SPCC1672.11c", "O14022", "SPAC29A4.19c" ] }, "reaction_10739257": { "compartment": "compartment_876", "id": "reaction_10739257", "reactome": "R-SPO-432049", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10739254", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10740300": { "compartment": "compartment_20699", "id": "reaction_10740300", "reactome": "R-SPO-742373", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742353" ], "products": [ "species_742361" ], "modifiers": [ [ "species_10740294", "catalyst" ] ], "additional_components": [ "SPBC1734.09" ] }, "reaction_10740787": { "compartment": "compartment_20699", "id": "reaction_10740787", "reactome": "R-SPO-936883", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_113592", "species_29356" ], "products": [ "species_29370", "species_167012", "species_29372" ], "modifiers": [ [ "species_10740784", "catalyst" ] ], "additional_components": [ "O59868", "SPBC31E1.02c", "species_29926" ] }, "reaction_10739115": { "compartment": "compartment_876", "id": "reaction_10739115", "reactome": "R-SPO-429101", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429130", "species_351626" ], "products": [ "species_70106", "species_426910" ], "modifiers": [ [ "species_10739112", "catalyst" ] ], "additional_components": [ "SPAC4F8.15" ] }, "reaction_10739331": { "compartment": "compartment_1462052", "id": "reaction_10739331", "reactome": "R-SPO-437085", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10739328", "catalyst" ] ], "additional_components": [ "SPAC17D4.03c" ] }, "reaction_10740662": { "compartment": "compartment_74700", "id": "reaction_10740662", "reactome": "R-SPO-917841", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113592", "species_29356" ], "products": [ "species_29370", "species_74722", "species_29372" ], "modifiers": [ [ "species_10732848", "catalyst" ] ], "additional_components": [ "P50515", "SPAC1B3.14", "O43046", "SPBC3B9.18c", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O59823", "SPCC965.03", "O14046", "SPAC2C4.13", "O13742", "SPAC16E8.07c", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q69Z14", "SPBC1685.16", "Q9HDW6", "SPAPB2B4.05" ] }, "reaction_10749527": { "compartment": "compartment_70101", "id": "reaction_10749527", "reactome": "R-SPO-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5692450" ], "products": [ "species_29370", "species_29372", "species_5692484" ], "modifiers": [ [ "species_10749524", "catalyst" ] ], "additional_components": [ "O74431", "SPCC1672.11c", "O14022", "SPAC29A4.19c" ] }, "reaction_10754737": { "compartment": "compartment_70101", "id": "reaction_10754737", "reactome": "R-SPO-8866553", "name": "misfolded CFTR is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754735" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9P7V2", "SPAC30.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10740153": { "compartment": "compartment_876", "id": "reaction_10740153", "reactome": "R-SPO-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10755496": { "compartment": "compartment_70101", "id": "reaction_10755496", "reactome": "R-SPO-8875902", "name": "SLC45A3 transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10755493", "catalyst" ] ], "additional_components": [ "SPAC2F3.08" ] }, "reaction_10745471": { "compartment": "compartment_70101", "id": "reaction_10745471", "reactome": "R-SPO-5223317", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5223341", "species_113592", "species_29356" ], "products": [ "species_29370", "species_29372", "species_5223344" ], "modifiers": [ [ "species_10745468", "catalyst" ] ], "additional_components": [ "P78966", "SPBC25B2.02c" ] }, "reaction_10745674": { "compartment": "compartment_70101", "id": "reaction_10745674", "reactome": "R-SPO-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10745671", "catalyst" ] ], "additional_components": [ "SPAPB17E12.11" ] }, "reaction_10738200": { "compartment": "compartment_70616", "id": "reaction_10738200", "reactome": "R-SPO-382560", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_189444", "species_113593" ], "products": [ "species_113548", "species_113581", "species_71185" ], "modifiers": [ [ "species_10738197", "catalyst" ] ], "additional_components": [ "Q02592", "SPCC737.09c", "O14286", "SPAC15A10.01", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10739371": { "compartment": "compartment_12045", "id": "reaction_10739371", "reactome": "R-SPO-442393", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_442320" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10739368", "catalyst" ] ], "additional_components": [ "SPAP8A3.03" ] }, "reaction_10743495": { "compartment": "compartment_70101", "id": "reaction_10743495", "reactome": "R-SPO-2684901", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10743492", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "O13621", "SPBC691.05c" ] }, "reaction_10739417": { "compartment": "compartment_876", "id": "reaction_10739417", "reactome": "R-SPO-445714", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10739414", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10740665": { "compartment": "compartment_876", "id": "reaction_10740665", "reactome": "R-SPO-917870", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310" ], "products": [ "species_9707308" ], "modifiers": [ [ "species_10736861", "catalyst" ] ], "additional_components": [ "species_189444", "CHEBI:36144", "species_189444", "CHEBI:36144", "SPAC14C4.07" ] }, "reaction_10741727": { "compartment": "compartment_70101", "id": "reaction_10741727", "reactome": "R-SPO-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_1454930" ], "products": [ "species_29370", "species_1454919", "species_29372" ], "modifiers": [ [ "species_10741724", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q10185", "SPAC3F10.11c", "Q9P7V2", "SPAC30.04c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10740150": { "compartment": "compartment_876", "id": "reaction_10740150", "reactome": "R-SPO-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10738220": { "compartment": "compartment_876", "id": "reaction_10738220", "reactome": "R-SPO-383190", "name": "HCO3- transport through ion channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_29356" ], "products": [ "species_29370", "species_425425", "species_29372" ], "modifiers": [ [ "species_10738217", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10745669": { "compartment": "compartment_70101", "id": "reaction_10745669", "reactome": "R-SPO-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10745666", "catalyst" ] ], "additional_components": [ "SPAPB17E12.11" ] }, "reaction_10743514": { "compartment": "compartment_70101", "id": "reaction_10743514", "reactome": "R-SPO-2730692", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2731008" ], "products": [ "species_352022", "species_74722" ], "modifiers": [ [ "species_10743511", "catalyst" ] ], "additional_components": [ "O94287", "SPBC887.02", "O60159", "SPBC19C7.11" ] }, "reaction_10739264": { "compartment": "compartment_876", "id": "reaction_10739264", "reactome": "R-SPO-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10739261", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10749518": { "compartment": "compartment_70101", "id": "reaction_10749518", "reactome": "R-SPO-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29418", "species_29356" ], "products": [ "species_29370", "species_29372", "species_1981162" ], "modifiers": [ [ "species_10749515", "catalyst" ] ], "additional_components": [ "SPACUNK4.07c" ] }, "reaction_10754739": { "compartment": "compartment_876", "id": "reaction_10754739", "reactome": "R-SPO-8866851", "name": "CFTR transits to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754733" ], "products": [ "species_10738217" ], "modifiers": [], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c", "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10739339": { "compartment": "compartment_876", "id": "reaction_10739339", "reactome": "R-SPO-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10739336", "catalyst" ] ], "additional_components": [ "SPBC23G7.16" ] }, "reaction_10749496": { "compartment": "compartment_70101", "id": "reaction_10749496", "reactome": "R-SPO-5691131", "name": "CANDI binds CUL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749492", "species_10735499" ], "products": [ "species_10749494" ], "modifiers": [], "additional_components": [ "SPAC1565.07c", "SPAC17G6.12", "Q9P3A8", "SPAC1565.07c", "O13790", "SPAC17G6.12" ] }, "reaction_10740297": { "compartment": "compartment_20699", "id": "reaction_10740297", "reactome": "R-SPO-742354", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756" ], "products": [ "species_914003" ], "modifiers": [ [ "species_10740294", "catalyst" ] ], "additional_components": [ "SPBC1734.09" ] }, "reaction_10740281": { "compartment": "compartment_20699", "id": "reaction_10740281", "reactome": "R-SPO-741450", "name": "SLC35A3 exchanges UDP-GlcNAc for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735698", "species_162756" ], "products": [ "species_109402", "species_914003" ], "modifiers": [ [ "species_10740278", "catalyst" ] ], "additional_components": [ "SPCC1795.03" ] }, "reaction_10734940": { "compartment": "compartment_70616", "id": "reaction_10734940", "reactome": "R-SPO-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113592", "species_113581" ], "modifiers": [ [ "species_10734937", "catalyst" ] ], "additional_components": [ "Q09188", "SPBC530.10c" ] }, "reaction_10741748": { "compartment": "compartment_876", "id": "reaction_10741748", "reactome": "R-SPO-1467457", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1131652", "species_113592", "species_29356" ], "products": [ "species_29370", "species_29372", "species_1467459" ], "modifiers": [ [ "species_10741745", "catalyst" ] ], "additional_components": [ "Q02592", "SPCC737.09c", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10740795": { "compartment": "compartment_20699", "id": "reaction_10740795", "reactome": "R-SPO-936895", "name": "ATP7B transports cytosolic Cu2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_209799" ], "products": [ "species_29370", "species_936901", "species_29372" ], "modifiers": [ [ "species_10740792", "catalyst" ] ], "additional_components": [ "SPBC29A3.01" ] }, "reaction_10740273": { "compartment": "compartment_20699", "id": "reaction_10740273", "reactome": "R-SPO-727759", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_727753" ], "modifiers": [ [ "species_10740270", "catalyst" ] ], "additional_components": [ "SPBC21B10.09" ] }, "reaction_10740164": { "compartment": "compartment_876", "id": "reaction_10740164", "reactome": "R-SPO-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10740159", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10747157": { "compartment": "compartment_984", "id": "reaction_10747157", "reactome": "R-SPO-5678706", "name": "ABCB4 transports PC from plasma membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_429802", "species_29356" ], "products": [ "species_29370", "species_382539", "species_29372" ], "modifiers": [ [ "species_10747154", "catalyst" ] ], "additional_components": [ "Q02592", "SPCC737.09c", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10755815": { "compartment": "compartment_70101", "id": "reaction_10755815", "reactome": "R-SPO-8932851", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8932838" ], "products": [ "species_8932842" ], "modifiers": [ [ "species_10755812", "catalyst" ] ], "additional_components": [ "CHEBI:32513", "species_1131871", "species_29468", "CHEBI:32513", "species_1131871", "species_29468", "SPAC17C9.10" ] }, "reaction_10757945": { "compartment": "compartment_70101", "id": "reaction_10757945", "reactome": "R-SPO-9696271", "name": "RND1 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738543", "species_10757941" ], "products": [ "species_10757943" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9UTL2", "SPAC144.14", "Q9USZ0", "SPBC1306.02", "Q9USR1", "SPBC577.08c", "Q9USI5", "SPCC645.14c", "P08647", "SPAC17H9.09c", "O43023", "SPBC354.09c", "Q9UTL2", "SPAC144.14", "Q9HE04", "SPAC20H4.11c", "Q9USZ0", "SPBC1306.02", "Q9USR1", "SPBC577.08c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9USI5", "SPCC645.14c", "P08647", "SPAC17H9.09c", "O43023", "SPBC354.09c" ] }, "reaction_10757947": { "compartment": "compartment_70101", "id": "reaction_10757947", "reactome": "R-SPO-9696274", "name": "RND1 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10738541" ], "products": [ "species_10738543" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10733685": { "compartment": "compartment_7660", "id": "reaction_10733685", "reactome": "R-SPO-83788", "name": "Binding of TFIIIC to Type 2 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733480", "species_83747" ], "products": [ "species_10733683" ], "modifiers": [], "additional_components": [ "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733689": { "compartment": "compartment_7660", "id": "reaction_10733689", "reactome": "R-SPO-83790", "name": "Binding of TFIIIB to TFIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733683", "species_10733448" ], "products": [ "species_10733687" ], "modifiers": [], "additional_components": [ "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9UST7", "SPBC336.07", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733681": { "compartment": "compartment_7660", "id": "reaction_10733681", "reactome": "R-SPO-83723", "name": "Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733484", "species_10733448" ], "products": [ "species_10733486" ], "modifiers": [], "additional_components": [ "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "Q9UST7", "SPBC336.07", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733547": { "compartment": "compartment_7660", "id": "reaction_10733547", "reactome": "R-SPO-76056", "name": "Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733543", "species_10733486" ], "products": [ "species_10733545" ], "modifiers": [], "additional_components": [ "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "O13877", "SPAC1B3.12c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74857", "SPCC18.07", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "Q9UST7", "SPBC336.07", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O13650", "SPBC8D2.07c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "Q9P6R0", "SPBC13E7.10c", "O13877", "SPAC1B3.12c", "O74458", "SPCC16C4.14c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "O94481", "SPCC1919.14c", "Q92399", "SPBC14C8.12", "Q9UST7", "SPBC336.07", "O74857", "SPCC18.07", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733693": { "compartment": "compartment_7660", "id": "reaction_10733693", "reactome": "R-SPO-83805", "name": "Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733543", "species_10733687" ], "products": [ "species_10733691" ], "modifiers": [], "additional_components": [ "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "O13877", "SPAC1B3.12c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74857", "SPCC18.07", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9UST7", "SPBC336.07", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O13650", "SPBC8D2.07c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "Q9P6R0", "SPBC13E7.10c", "O13877", "SPAC1B3.12c", "O74458", "SPCC16C4.14c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "O94481", "SPCC1919.14c", "Q92399", "SPBC14C8.12", "Q9UST7", "SPBC336.07", "O74857", "SPCC18.07", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10736346": { "compartment": "compartment_876", "id": "reaction_10736346", "reactome": "R-SPO-196017", "name": "Dynamin is recruited to the gap junction plaque", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736046", "species_10736019" ], "products": [ "species_10736048" ], "modifiers": [], "additional_components": [ "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "O60054", "SPBC56F2.03", "P10989", "SPBC32H8.12c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q09718", "SPAC31A2.09c", "O60054", "SPBC56F2.03", "Q9URZ5", "SPAC767.01c", "P10989", "SPBC32H8.12c" ] }, "reaction_10739285": { "compartment": "compartment_17906", "id": "reaction_10739285", "reactome": "R-SPO-434382", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_200993" ], "modifiers": [ [ "species_10739282", "catalyst" ] ], "additional_components": [ "Q9P7D7", "SPBP4H10.11c", "O60135", "SPBC18H10.02" ] }, "reaction_10737145": { "compartment": "compartment_876", "id": "reaction_10737145", "reactome": "R-SPO-202692", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10734488" ], "products": [ "species_10737143" ], "modifiers": [], "additional_components": [ "SPAC1F7.04", "Q09914", "SPAC1F7.04", "species_179838" ] }, "reaction_10742675": { "compartment": "compartment_12045", "id": "reaction_10742675", "reactome": "R-SPO-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10742672", "catalyst" ] ], "additional_components": [ "species_74016", "P40977", "SPAC22F8.11" ] }, "reaction_10742665": { "compartment": "compartment_70101", "id": "reaction_10742665", "reactome": "R-SPO-1855205", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_114520", "species_29372" ], "modifiers": [ [ "species_10742662", "catalyst" ] ], "additional_components": [ "O94526", "SPBC609.02", "species_29926" ] }, "reaction_10742633": { "compartment": "compartment_70101", "id": "reaction_10742633", "reactome": "R-SPO-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10742630", "catalyst" ] ], "additional_components": [ "species_74016", "P40977", "SPAC22F8.11" ] }, "reaction_10742706": { "compartment": "compartment_876", "id": "reaction_10742706", "reactome": "R-SPO-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10742703", "catalyst" ] ], "additional_components": [ "species_74016", "P40977", "SPAC22F8.11" ] }, "reaction_10742681": { "compartment": "compartment_70101", "id": "reaction_10742681", "reactome": "R-SPO-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_994123", "species_29372" ], "modifiers": [ [ "species_10742605", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "Q9USQ6", "SPBC577.13" ] }, "reaction_10756065": { "compartment": "compartment_876", "id": "reaction_10756065", "reactome": "R-SPO-8943279", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247892", "species_109276" ], "products": [ "species_210382", "species_1247934" ], "modifiers": [ [ "species_10745932", "catalyst" ] ], "additional_components": [ "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10741599": { "compartment": "compartment_70101", "id": "reaction_10741599", "reactome": "R-SPO-1247935", "name": "OPLAH hydrolyses OPRO to L-Glu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1247942", "species_29356" ], "products": [ "species_29370", "species_29404", "species_29372" ], "modifiers": [ [ "species_10741596", "catalyst" ] ], "additional_components": [ "Q10094", "SPAC11D3.15" ] }, "reaction_10741589": { "compartment": "compartment_70101", "id": "reaction_10741589", "reactome": "R-SPO-1247910", "name": "CNDP2:2Mn2+ dimer hydrolyses CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247904", "species_29356" ], "products": [ "species_29424", "species_111707" ], "modifiers": [ [ "species_10741586", "catalyst" ] ], "additional_components": [ "Q9P6I2", "SPBC1198.08", "species_113527" ] }, "reaction_10735542": { "compartment": "compartment_70101", "id": "reaction_10735542", "reactome": "R-SPO-174367", "name": "GCL ligates L-Glu to L-Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111707", "species_29404" ], "products": [ "species_29370", "species_174393", "species_29372" ], "modifiers": [ [ "species_10735539", "catalyst" ] ], "additional_components": [ "O94246", "SPCC737.06c", "Q09768", "SPAC22F3.10c" ] }, "reaction_10735581": { "compartment": "compartment_70101", "id": "reaction_10735581", "reactome": "R-SPO-174394", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_174393", "species_113592" ], "products": [ "species_29370", "species_29450", "species_29372" ], "modifiers": [ [ "species_10735578", "catalyst" ], [ "species_29450", "inhibitor" ] ], "additional_components": [ "P35669", "SPAC3F10.04", "species_29926" ] }, "reaction_10750414": { "compartment": "compartment_70101", "id": "reaction_10750414", "reactome": "R-SPO-6785928", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450" ], "products": [ "species_1247904", "species_1247942" ], "modifiers": [ [ "species_10750411", "catalyst" ] ], "additional_components": [ "P87305", "SPBC31F10.03" ] }, "reaction_10757128": { "compartment": "compartment_17947", "id": "reaction_10757128", "reactome": "R-SPO-9033527", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757089", "species_10756376" ], "products": [ "species_10757091" ], "modifiers": [], "additional_components": [ "O60065", "SPBC13G1.03c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10" ] }, "reaction_10757083": { "compartment": "compartment_17947", "id": "reaction_10757083", "reactome": "R-SPO-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757067" ], "products": [ "species_10757081", "species_10756372" ], "modifiers": [], "additional_components": [ "O60065", "SPBC13G1.03c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "O94325", "SPBC725.07", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14077", "SPACUNK4.12c", "Q9Y7N4", "SPCC1450.07c", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O14136", "SPAC3C7.10", "O13717", "SPAC14C4.10c", "O14077", "SPACUNK4.12c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "Q9Y7N4", "SPCC1450.07c", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O13717", "SPAC14C4.10c", "O60065", "SPBC13G1.03c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10" ] }, "reaction_10757096": { "compartment": "compartment_17947", "id": "reaction_10757096", "reactome": "R-SPO-9033485", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757091" ], "products": [ "species_10741537", "species_10757093" ], "modifiers": [ [ "species_10757091", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P78798", "SPAC17D4.01", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10" ] }, "reaction_10757085": { "compartment": "compartment_17947", "id": "reaction_10757085", "reactome": "R-SPO-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757063", "species_10757065" ], "products": [ "species_10757067" ], "modifiers": [], "additional_components": [ "O14077", "SPACUNK4.12c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "Q9Y7N4", "SPCC1450.07c", "O94325", "SPBC725.07", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O13717", "SPAC14C4.10c", "O60065", "SPBC13G1.03c", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10", "O60065", "SPBC13G1.03c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "O94325", "SPBC725.07", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14077", "SPACUNK4.12c", "Q9Y7N4", "SPCC1450.07c", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O14136", "SPAC3C7.10", "O13717", "SPAC14C4.10c" ] }, "reaction_10736821": { "compartment": "compartment_70101", "id": "reaction_10736821", "reactome": "R-SPO-200423", "name": "pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736809", "species_113592" ], "products": [ "species_29370", "species_10736816" ], "modifiers": [ [ "species_10736818", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527", "P78820", "SPAC56E4.04c", "species_113527", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10755610": { "compartment": "compartment_70101", "id": "reaction_10755610", "reactome": "R-SPO-8876889", "name": "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10736809", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527" ] }, "reaction_10733326": { "compartment": "compartment_70101", "id": "reaction_10733326", "reactome": "R-SPO-75851", "name": "Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10733323", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527" ] }, "reaction_10736829": { "compartment": "compartment_17927", "id": "reaction_10736829", "reactome": "R-SPO-200424", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_201023", "species_201034" ], "products": [ "species_549207", "species_201050" ], "modifiers": [ [ "species_10736826", "catalyst" ] ], "additional_components": [ "SPBC29A3.11c" ] }, "reaction_10757932": { "compartment": "compartment_70101", "id": "reaction_10757932", "reactome": "R-SPO-9696267", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757928" ], "products": [ "species_10757930" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10729657": { "compartment": "compartment_70101", "id": "reaction_10729657", "reactome": "R-SPO-70286", "name": "UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29494", "species_29548" ], "products": [ "species_29410", "species_111294" ], "modifiers": [ [ "species_10729654", "catalyst" ] ], "additional_components": [ "P78811", "SPCC1322.04" ] }, "reaction_10729379": { "compartment": "compartment_7660", "id": "reaction_10729379", "reactome": "R-SPO-68954", "name": "Mcm2-7 is phosphorylated by DDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728861", "species_29358" ], "products": [ "species_113582", "species_10729376" ], "modifiers": [ [ "species_10728818", "catalyst" ] ], "additional_components": [ "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "species_29372", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "P50582", "SPBC776.12c", "O59836", "SPCC550.13" ] }, "reaction_10728884": { "compartment": "compartment_7660", "id": "reaction_10728884", "reactome": "R-SPO-68916", "name": "DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728877", "species_10728792" ], "products": [ "species_10728879" ], "modifiers": [], "additional_components": [ "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "Q92373", "SPCC1753.01c", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "Q92374", "SPCC23B6.05c", "O74796", "SPBC2A9.12", "Q92372", "SPBC660.13c", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728903": { "compartment": "compartment_7660", "id": "reaction_10728903", "reactome": "R-SPO-68940", "name": "Cdt1 is displaced from the pre-replicative complex.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728899" ], "products": [ "species_10728893", "species_10728873" ], "modifiers": [], "additional_components": [ "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "SPBC428.18", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728886": { "compartment": "compartment_7660", "id": "reaction_10728886", "reactome": "R-SPO-68917", "name": "Cdc45 associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728797", "species_10728875" ], "products": [ "species_10728877" ], "modifiers": [], "additional_components": [ "SPAC17D4.02", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10729381": { "compartment": "compartment_7660", "id": "reaction_10729381", "reactome": "R-SPO-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68419", "species_10728764" ], "products": [ "species_10728766" ], "modifiers": [ [ "species_10728879", "catalyst" ] ], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "Q92373", "SPCC1753.01c", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "Q92374", "SPCC23B6.05c", "O74796", "SPBC2A9.12", "Q92372", "SPBC660.13c", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728888": { "compartment": "compartment_7660", "id": "reaction_10728888", "reactome": "R-SPO-68918", "name": "CDK and DDK associate with the Mcm10:pre-replicative complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728806", "species_10728818", "species_10728873" ], "products": [ "species_10728875" ], "modifiers": [], "additional_components": [ "P04551", "SPBC11B10.09", "P50582", "SPBC776.12c", "O59836", "SPCC550.13", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728901": { "compartment": "compartment_7660", "id": "reaction_10728901", "reactome": "R-SPO-68919", "name": "Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728823", "species_10728897" ], "products": [ "species_10728899" ], "modifiers": [], "additional_components": [ "SPBC1347.10", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728881": { "compartment": "compartment_7660", "id": "reaction_10728881", "reactome": "R-SPO-68914", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728766", "species_10728742" ], "products": [ "species_10728768" ], "modifiers": [ [ "species_10728879", "catalyst" ] ], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "Q92373", "SPCC1753.01c", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "Q92374", "SPCC23B6.05c", "O74796", "SPBC2A9.12", "Q92372", "SPBC660.13c", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10745090": { "compartment": "compartment_7660", "id": "reaction_10745090", "reactome": "R-SPO-5082356", "name": "HSF1-mediated gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744254" ], "products": [ "species_10745068" ], "modifiers": [ [ "species_10745088", "catalyst" ], [ "species_10745078", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14330", "SPBC16E9.15", "P41887", "SPAC926.04c", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10745122": { "compartment": "compartment_7660", "id": "reaction_10745122", "reactome": "R-SPO-5082405", "name": "Phosphorylation of HSF1 at Ser326 induces transactivation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10744252" ], "products": [ "species_113582", "species_10745088" ], "modifiers": [ [ "species_10745119", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q9Y7K2", "SPBC216.07c", "P87141", "SPAC57A7.11", "O74184", "SPBC21B10.05c" ] }, "reaction_10742668": { "compartment": "compartment_7660", "id": "reaction_10742668", "reactome": "R-SPO-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742651": { "compartment": "compartment_70101", "id": "reaction_10742651", "reactome": "R-SPO-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10742646", "catalyst" ] ], "additional_components": [ "SPCC1672.06c" ] }, "reaction_10742712": { "compartment": "compartment_7660", "id": "reaction_10742712", "reactome": "R-SPO-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023940", "species_29358" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742814": { "compartment": "compartment_70101", "id": "reaction_10742814", "reactome": "R-SPO-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_2023974", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "CHEBI:62922", "species_1629740", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742641": { "compartment": "compartment_7660", "id": "reaction_10742641", "reactome": "R-SPO-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742603": { "compartment": "compartment_70101", "id": "reaction_10742603", "reactome": "R-SPO-1855166", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023943", "species_29356" ], "products": [ "species_29372", "species_994141" ], "modifiers": [ [ "species_10742591", "catalyst" ] ], "additional_components": [ "species_1629736", "species_1629755", "CHEBI:62927", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742657": { "compartment": "compartment_70101", "id": "reaction_10742657", "reactome": "R-SPO-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742715": { "compartment": "compartment_70101", "id": "reaction_10742715", "reactome": "R-SPO-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629765" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742580": { "compartment": "compartment_70101", "id": "reaction_10742580", "reactome": "R-SPO-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742654": { "compartment": "compartment_70101", "id": "reaction_10742654", "reactome": "R-SPO-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742616": { "compartment": "compartment_7660", "id": "reaction_10742616", "reactome": "R-SPO-1855176", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023929" ], "modifiers": [ [ "species_10742613", "catalyst" ] ], "additional_components": [ "SPCC4B3.10c" ] }, "reaction_10742812": { "compartment": "compartment_70101", "id": "reaction_10742812", "reactome": "R-SPO-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023974", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "CHEBI:62922", "species_1629740", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742709": { "compartment": "compartment_70101", "id": "reaction_10742709", "reactome": "R-SPO-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742718": { "compartment": "compartment_7660", "id": "reaction_10742718", "reactome": "R-SPO-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023922", "species_29358" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742678": { "compartment": "compartment_70101", "id": "reaction_10742678", "reactome": "R-SPO-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10742646", "catalyst" ] ], "additional_components": [ "SPCC1672.06c" ] }, "reaction_10742567": { "compartment": "compartment_7660", "id": "reaction_10742567", "reactome": "R-SPO-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742600": { "compartment": "compartment_70101", "id": "reaction_10742600", "reactome": "R-SPO-1855165", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_1629765", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742660": { "compartment": "compartment_70101", "id": "reaction_10742660", "reactome": "R-SPO-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742638": { "compartment": "compartment_70101", "id": "reaction_10742638", "reactome": "R-SPO-1855179", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629770" ], "modifiers": [ [ "species_10742635", "catalyst" ] ], "additional_components": [ "SPCC4B3.10c" ] }, "reaction_10742608": { "compartment": "compartment_70101", "id": "reaction_10742608", "reactome": "R-SPO-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114520", "species_29356" ], "products": [ "species_1629739", "species_29372" ], "modifiers": [ [ "species_10742605", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "Q9USQ6", "SPBC577.13" ] }, "reaction_10741541": { "compartment": "compartment_70101", "id": "reaction_10741541", "reactome": "R-SPO-1236970", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236719" ], "products": [ "species_983036", "species_8942986" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10733749": { "compartment": "compartment_70101", "id": "reaction_10733749", "reactome": "R-SPO-109702", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733734", "species_113592" ], "products": [ "species_29370", "species_10733746" ], "modifiers": [ [ "species_10733718", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10732851": { "compartment": "compartment_17940", "id": "reaction_10732851", "reactome": "R-SPO-74723", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_74722" ], "modifiers": [ [ "species_10732848", "catalyst" ] ], "additional_components": [ "P50515", "SPAC1B3.14", "O43046", "SPBC3B9.18c", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O59823", "SPCC965.03", "O14046", "SPAC2C4.13", "O13742", "SPAC16E8.07c", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q69Z14", "SPBC1685.16", "Q9HDW6", "SPAPB2B4.05" ] }, "reaction_10733720": { "compartment": "compartment_876", "id": "reaction_10733720", "reactome": "R-SPO-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733716", "species_179838" ], "products": [ "species_10733718" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10738628": { "compartment": "compartment_876", "id": "reaction_10738628", "reactome": "R-SPO-418574", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738468" ], "products": [ "species_10738625" ], "modifiers": [ [ "species_10738468", "catalyst" ] ], "additional_components": [ "species_29438", "Q04665", "SPAC23H3.13c", "species_111349", "Q04665", "SPAC23H3.13c", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10738681": { "compartment": "compartment_70101", "id": "reaction_10738681", "reactome": "R-SPO-419166", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738582", "species_29438" ], "products": [ "species_10738584", "species_29420" ], "modifiers": [ [ "species_10738678", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_111349", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q09763", "SPAC24H6.09", "O59679", "SPBC29A3.17", "Q9HGL2", "SPBC800.10c", "Q9USU1", "SPBC336.03", "P26674", "SPCC1442.01" ] }, "reaction_10738831": { "compartment": "compartment_70101", "id": "reaction_10738831", "reactome": "R-SPO-425861", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738827", "species_114519" ], "products": [ "species_10738829" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10734572": { "compartment": "compartment_876", "id": "reaction_10734572", "reactome": "R-SPO-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734567" ], "products": [ "species_10734569" ], "modifiers": [ [ "species_10734143", "catalyst" ] ], "additional_components": [ "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c", "species_179856", "species_114520", "species_1500596", "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c", "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c" ] }, "reaction_10738483": { "compartment": "compartment_876", "id": "reaction_10738483", "reactome": "R-SPO-400015", "name": "Diacylgycerol activates Protein kinase C, alpha type", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734508", "species_114519" ], "products": [ "species_10738481" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10757183": { "compartment": "compartment_70101", "id": "reaction_10757183", "reactome": "R-SPO-9603279", "name": "PIP3 recruits PDK1 and AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10737088", "species_10738396" ], "products": [ "species_10757181" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q12701", "SPCC576.15c" ] }, "reaction_10738633": { "compartment": "compartment_876", "id": "reaction_10738633", "reactome": "R-SPO-418582", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734141" ], "products": [ "species_10738630" ], "modifiers": [ [ "species_10734141", "catalyst" ] ], "additional_components": [ "species_29438", "Q04665", "SPAC23H3.13c", "species_111349", "Q04665", "SPAC23H3.13c", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10756978": { "compartment": "compartment_70101", "id": "reaction_10756978", "reactome": "R-SPO-9020253", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024781", "species_29356" ], "products": [ "species_9024809" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:138649", "CHEBI:138648", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756976": { "compartment": "compartment_70101", "id": "reaction_10756976", "reactome": "R-SPO-9020252", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024602", "species_29356" ], "products": [ "species_9024574" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:138179", "CHEBI:138614", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756982": { "compartment": "compartment_70101", "id": "reaction_10756982", "reactome": "R-SPO-9020258", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024768" ], "products": [ "species_9024759" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:81565", "CHEBI:81564", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756984": { "compartment": "compartment_70101", "id": "reaction_10756984", "reactome": "R-SPO-9020270", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024577" ], "products": [ "species_9024570" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:138616", "CHEBI:138615", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10736344": { "compartment": "compartment_70101", "id": "reaction_10736344", "reactome": "R-SPO-195664", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_195691" ], "products": [ "species_29366", "species_195655", "species_29356" ], "modifiers": [ [ "species_10736341", "catalyst" ] ], "additional_components": [ "O13666", "SPBC27B12.03c", "O94457", "SPAC1687.16c" ] }, "reaction_10737982": { "compartment": "compartment_70101", "id": "reaction_10737982", "reactome": "R-SPO-372449", "name": "phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] => phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_372364", "species_76190" ], "products": [ "species_29654", "species_29492" ], "modifiers": [ [ "species_10733305", "catalyst" ] ], "additional_components": [ "SPAC19G12.05" ] }, "reaction_10729759": { "compartment": "compartment_70101", "id": "reaction_10729759", "reactome": "R-SPO-70454", "name": "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75970" ], "products": [ "species_29578" ], "modifiers": [ [ "species_10729756", "catalyst" ] ], "additional_components": [ "P07669", "SPCC24B10.21" ] }, "reaction_10730569": { "compartment": "compartment_5460", "id": "reaction_10730569", "reactome": "R-SPO-71783", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113587", "species_113529" ], "products": [ "species_113526", "species_113544" ], "modifiers": [ [ "species_10730123", "catalyst" ] ], "additional_components": [ "Q9Y7R8", "SPCC306.08c" ] }, "reaction_10729720": { "compartment": "compartment_70101", "id": "reaction_10729720", "reactome": "R-SPO-70420", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_70113" ], "products": [ "species_70106", "species_29370", "species_30537" ], "modifiers": [ [ "species_10729717", "catalyst" ] ], "additional_components": [ "P50521", "SPAC4F8.07c", "Q09756", "SPAC24H6.04" ] }, "reaction_10751283": { "compartment": "compartment_70101", "id": "reaction_10751283", "reactome": "R-SPO-6798335", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800" ], "products": [ "species_6798337" ], "modifiers": [ [ "species_10751280", "catalyst" ] ], "additional_components": [ "P36623", "SPAC26F1.06" ] }, "reaction_10729809": { "compartment": "compartment_70101", "id": "reaction_10729809", "reactome": "R-SPO-70479", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10729806", "catalyst" ], [ "species_76577", "inhibitor" ] ], "additional_components": [ "species_29926", "P09202", "SPBC1198.14c" ] }, "reaction_10729793": { "compartment": "compartment_70101", "id": "reaction_10729793", "reactome": "R-SPO-70475", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10729788", "catalyst" ] ], "additional_components": [ "P78917", "SPBC1604.05" ] }, "reaction_10730470": { "compartment": "compartment_70101", "id": "reaction_10730470", "reactome": "R-SPO-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10730467", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_30389", "inhibitor" ], [ "species_29358", "inhibitor" ] ], "additional_components": [ "Q10208", "SPAC4H3.10c", "species_74126", "species_29926" ] }, "reaction_10735464": { "compartment": "compartment_13231", "id": "reaction_10735464", "reactome": "R-SPO-170825", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735462" ], "products": [ "species_10729703" ], "modifiers": [], "additional_components": [ "P50521", "SPAC4F8.07c", "Q09756", "SPAC24H6.04", "P50521", "SPAC4F8.07c", "Q09756", "SPAC24H6.04" ] }, "reaction_10756422": { "compartment": "compartment_70101", "id": "reaction_10756422", "reactome": "R-SPO-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800", "species_30537" ], "products": [ "species_70106", "species_29728", "species_8955759" ], "modifiers": [ [ "species_10729642", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10730609": { "compartment": "compartment_70101", "id": "reaction_10730609", "reactome": "R-SPO-71850", "name": "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_29800" ], "products": [ "species_113592", "species_29728" ], "modifiers": [ [ "species_10729826", "catalyst" ] ], "additional_components": [ "O60101", "SPBC14F5.04c", "species_29926" ] }, "reaction_10729856": { "compartment": "compartment_70101", "id": "reaction_10729856", "reactome": "R-SPO-70494", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29492", "species_29356" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10729853", "catalyst" ] ], "additional_components": [ "P40370", "SPBC1815.01", "Q8NKC2", "SPBPB21E7.01c", "species_29926" ] }, "reaction_10730452": { "compartment": "compartment_70101", "id": "reaction_10730452", "reactome": "R-SPO-71654", "name": "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29728" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10730341", "catalyst" ] ], "additional_components": [ "P36623", "SPAC26F1.06" ] }, "reaction_10729813": { "compartment": "compartment_70101", "id": "reaction_10729813", "reactome": "R-SPO-70482", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_29800" ], "products": [ "species_29578", "species_29360", "species_29372" ], "modifiers": [ [ "species_10729746", "catalyst" ] ], "additional_components": [ "O43026", "SPBC354.12", "P78958", "SPBC32F12.11" ] }, "reaction_10729781": { "compartment": "compartment_70101", "id": "reaction_10729781", "reactome": "R-SPO-70467", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30014" ], "modifiers": [ [ "species_10729778", "catalyst" ], [ "species_29370", "catalyst" ], [ "species_76577", "catalyst" ], [ "species_30533", "catalyst" ], [ "species_113592", "inhibitor" ], [ "species_76190", "inhibitor" ] ], "additional_components": [ "O42938", "SPBC16H5.02" ] }, "reaction_10729631": { "compartment": "compartment_70101", "id": "reaction_10729631", "reactome": "R-SPO-70262", "name": "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30533", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10729628", "catalyst" ] ], "additional_components": [ "Q9URZ7", "SPAC732.02c" ] }, "reaction_10729866": { "compartment": "compartment_5460", "id": "reaction_10729866", "reactome": "R-SPO-70501", "name": "Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29376", "species_113557", "species_113593" ], "products": [ "species_113548", "species_113581", "species_113587" ], "modifiers": [ [ "species_10729863", "catalyst" ], [ "species_113559", "catalyst" ] ], "additional_components": [ "Q9UUE1", "SPBC17G9.11c", "species_199207", "species_113527" ] }, "reaction_10729960": { "compartment": "compartment_70101", "id": "reaction_10729960", "reactome": "R-SPO-70592", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_29406" ], "products": [ "species_29404", "species_76213" ], "modifiers": [ [ "species_10729955", "catalyst" ] ], "additional_components": [ "O42652", "SPAC10F6.13c" ] }, "reaction_10730605": { "compartment": "compartment_70101", "id": "reaction_10730605", "reactome": "R-SPO-71802", "name": "D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30533" ], "modifiers": [ [ "species_10730602", "catalyst" ], [ "species_30533", "catalyst" ] ], "additional_components": [ "Q9UTK9", "SPAC144.17c", "Q9URZ7", "SPAC732.02c" ] }, "reaction_10741799": { "compartment": "compartment_12045", "id": "reaction_10741799", "reactome": "R-SPO-1482545", "name": "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741812": { "compartment": "compartment_12045", "id": "reaction_10741812", "reactome": "R-SPO-1482571", "name": "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10733703": { "compartment": "compartment_70101", "id": "reaction_10733703", "reactome": "R-SPO-109624", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500173", "species_113592" ], "products": [ "species_29370", "species_500088" ], "modifiers": [ [ "species_10733700", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:17256", "species_76577", "species_109386", "P78825", "SPCC338.14", "species_29926" ] }, "reaction_10732725": { "compartment": "compartment_70101", "id": "reaction_10732725", "reactome": "R-SPO-74213", "name": "APRT catalyzes the conversion of adenine to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_83951" ], "products": [ "species_111294", "species_76577" ], "modifiers": [ [ "species_10732722", "catalyst" ] ], "additional_components": [ "O42842", "SPAC23A1.03" ] }, "reaction_10733571": { "compartment": "compartment_70101", "id": "reaction_10733571", "reactome": "R-SPO-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76577", "species_29356" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10733568", "catalyst" ] ], "additional_components": [ "P50998", "SPBC106.04" ] }, "reaction_10734236": { "compartment": "compartment_70101", "id": "reaction_10734236", "reactome": "R-SPO-112033", "name": "PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113599", "species_500244" ], "products": [ "species_500172", "species_29372" ], "modifiers": [ [ "species_10732732", "catalyst" ] ], "additional_components": [ "species_112016", "CHEBI:58576", "CHEBI:28997", "CHEBI:17596", "Q9UTG1", "SPAC1805.16c" ] }, "reaction_10734238": { "compartment": "compartment_70101", "id": "reaction_10734238", "reactome": "R-SPO-112034", "name": "PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500244", "species_83956" ], "products": [ "species_500245", "species_29372" ], "modifiers": [ [ "species_10732732", "catalyst" ] ], "additional_components": [ "species_112016", "CHEBI:58576", "CHEBI:17172", "CHEBI:16750", "Q9UTG1", "SPAC1805.16c" ] }, "reaction_10742023": { "compartment": "compartment_12045", "id": "reaction_10742023", "reactome": "R-SPO-1482892", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741900": { "compartment": "compartment_12045", "id": "reaction_10741900", "reactome": "R-SPO-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10741895", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741999": { "compartment": "compartment_12045", "id": "reaction_10741999", "reactome": "R-SPO-1482828", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10741996", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742019": { "compartment": "compartment_12045", "id": "reaction_10742019", "reactome": "R-SPO-1482884", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741905": { "compartment": "compartment_12045", "id": "reaction_10741905", "reactome": "R-SPO-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10741895", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10749926": { "compartment": "compartment_70101", "id": "reaction_10749926", "reactome": "R-SPO-5694583", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694568" ], "products": [ "species_5694580", "species_5694567" ], "modifiers": [ [ "species_10749923", "catalyst" ] ], "additional_components": [ "SPAC6G10.03c" ] }, "reaction_10743442": { "compartment": "compartment_70101", "id": "reaction_10743442", "reactome": "R-SPO-2534096", "name": "METAP1/2 demethylates GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743423" ], "products": [ "species_174390", "species_10743408" ], "modifiers": [ [ "species_10743439", "catalyst" ] ], "additional_components": [ "SPAC23H3.13c", "SPAC23H3.13c", "O60085", "SPBC14C8.03", "O59730", "SPBC3E7.10", "species_880069" ] }, "reaction_10743483": { "compartment": "compartment_70101", "id": "reaction_10743483", "reactome": "R-SPO-2586748", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10743469" ], "products": [ "species_10743481" ], "modifiers": [], "additional_components": [ "SPAC18B11.04", "species_74016", "Q09711", "SPAC18B11.04" ] }, "reaction_10743421": { "compartment": "compartment_70101", "id": "reaction_10743421", "reactome": "R-SPO-2534087", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2534019", "species_10743408" ], "products": [ "species_76194", "species_10743411" ], "modifiers": [ [ "species_10743416", "catalyst" ] ], "additional_components": [ "SPAC23H3.13c", "SPAC23H3.13c", "SPBC2G2.11" ] }, "reaction_10737739": { "compartment": "compartment_70101", "id": "reaction_10737739", "reactome": "R-SPO-266072", "name": "LTA4 is hydolysed to LTB4 by LTA4H", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265281", "species_29356" ], "products": [ "species_266056" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10737682": { "compartment": "compartment_876", "id": "reaction_10737682", "reactome": "R-SPO-266012", "name": "LTD4 is converted to LTE4 by DPEP1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_266074" ], "products": [ "species_266029", "species_266033" ], "modifiers": [ [ "species_10737679", "catalyst" ] ], "additional_components": [ "O59832", "SPCC965.12", "species_442320", "O14124", "SPCC965.12" ] }, "reaction_10737721": { "compartment": "compartment_876", "id": "reaction_10737721", "reactome": "R-SPO-266046", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266013", "species_109276" ], "products": [ "species_210382", "species_266074" ], "modifiers": [ [ "species_10737718", "catalyst" ] ], "additional_components": [ "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10737729": { "compartment": "compartment_876", "id": "reaction_10737729", "reactome": "R-SPO-266070", "name": "LTC4 is exported from the cytosol by ABCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266066" ], "products": [ "species_266013" ], "modifiers": [ [ "species_10737726", "catalyst" ] ], "additional_components": [ "SPAC3F10.11c" ] }, "reaction_10731420": { "compartment": "compartment_7660", "id": "reaction_10731420", "reactome": "R-SPO-72185", "name": "mRNA polyadenylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731415", "species_29358" ], "products": [ "species_10731327", "species_10731322", "species_10731417", "species_10731317" ], "modifiers": [ [ "species_10731327", "catalyst" ] ], "additional_components": [ "Q9P7J4", "SPCC24B10.11c", "Q09176", "SPAP8A3.06", "O74733", "SPBC1709.08", "Q09801", "SPAC22G7.10", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q9HEQ9", "SPBC660.11", "O74740", "SPBC1709.15c", "Q10267", "SPAC13G7.03", "Q10295", "SPBC646.04", "P36629", "SPBC146.07", "O14327", "SPBC16E9.12c", "Q09779", "SPAC1D4.14", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9UTD1", "SPAC227.08c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "SPBC646.04", "SPBC16E9.12c", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "Q9P383", "SPBC13A2.01c", "C6Y4C0", "SPAC222.18", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "Q10267", "SPAC13G7.03", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "SPBC646.04" ] }, "reaction_10730232": { "compartment": "compartment_70101", "id": "reaction_10730232", "reactome": "R-SPO-71249", "name": "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31503" ], "products": [ "species_29424", "species_31311" ], "modifiers": [ [ "species_10730229", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c" ] }, "reaction_10750452": { "compartment": "compartment_17951", "id": "reaction_10750452", "reactome": "R-SPO-6787811", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787810", "species_113535" ], "products": [ "species_6787814", "species_113575" ], "modifiers": [ [ "species_10750449", "catalyst" ] ], "additional_components": [ "Q9HDX2", "SPAPB1A11.03" ] }, "reaction_10738303": { "compartment": "compartment_17951", "id": "reaction_10738303", "reactome": "R-SPO-389611", "name": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389594" ], "products": [ "species_389578", "species_389636" ], "modifiers": [ [ "species_10738300", "catalyst" ] ], "additional_components": [ "species_29480", "Q9Y7M1", "SPBC725.04", "species_29926" ] }, "reaction_10756425": { "compartment": "compartment_5460", "id": "reaction_10756425", "reactome": "R-SPO-8955817", "name": "PRODH2 oxidises HPRO to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215", "species_113597" ], "products": [ "species_164934", "species_113521", "species_113590" ], "modifiers": [ [ "species_10750340", "catalyst" ] ], "additional_components": [ "SPCC70.03c" ] }, "reaction_10730032": { "compartment": "compartment_5460", "id": "reaction_10730032", "reactome": "R-SPO-70670", "name": "PRODH oxidises L-Pro to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_379717", "species_113597" ], "products": [ "species_164934", "species_113529", "species_113590" ], "modifiers": [ [ "species_10730029", "catalyst" ] ], "additional_components": [ "SPCC70.03c" ] }, "reaction_10740192": { "compartment": "compartment_7660", "id": "reaction_10740192", "reactome": "R-SPO-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739886", "species_517622" ], "products": [ "species_10740190" ], "modifiers": [], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03" ] }, "reaction_10739891": { "compartment": "compartment_7660", "id": "reaction_10739891", "reactome": "R-SPO-450533", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10730941" ], "products": [ "species_113582", "species_10739886" ], "modifiers": [ [ "species_10739888", "catalyst" ] ], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "SPBC12D12.04c" ] }, "reaction_10739874": { "compartment": "compartment_7660", "id": "reaction_10739874", "reactome": "R-SPO-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450613", "species_10730941" ], "products": [ "species_10739872" ], "modifiers": [], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03" ] }, "reaction_10739908": { "compartment": "compartment_7660", "id": "reaction_10739908", "reactome": "R-SPO-450550", "name": "PKCalpha phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10730941" ], "products": [ "species_113582", "species_10739899" ], "modifiers": [ [ "species_10739905", "catalyst" ] ], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10740188": { "compartment": "compartment_7660", "id": "reaction_10740188", "reactome": "R-SPO-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739899", "species_450605" ], "products": [ "species_10740186" ], "modifiers": [], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03" ] }, "reaction_10729539": { "compartment": "compartment_7660", "id": "reaction_10729539", "reactome": "R-SPO-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10729536", "catalyst" ] ], "additional_components": [ "SPAC20G8.01" ] }, "reaction_10729463": { "compartment": "compartment_7660", "id": "reaction_10729463", "reactome": "R-SPO-69063", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729459", "species_29358", "species_10729450" ], "products": [ "species_113582", "species_10729461" ], "modifiers": [], "additional_components": [ "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09" ] }, "reaction_10729493": { "compartment": "compartment_7660", "id": "reaction_10729493", "reactome": "R-SPO-69074", "name": "Formation of Processive Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729465", "species_10729489" ], "products": [ "species_10729491" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "Q03392", "SPBC16D10.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10729502": { "compartment": "compartment_7660", "id": "reaction_10729502", "reactome": "R-SPO-69127", "name": "Formation of the Flap Intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729495" ], "products": [ "species_10729500" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10729467": { "compartment": "compartment_7660", "id": "reaction_10729467", "reactome": "R-SPO-69068", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729461" ], "products": [ "species_10729465", "species_10729448" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "Q03392", "SPBC16D10.09", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c" ] }, "reaction_10729517": { "compartment": "compartment_7660", "id": "reaction_10729517", "reactome": "R-SPO-69142", "name": "Recruitment of Dna2 endonuclease", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729506", "species_10729513" ], "products": [ "species_10729515" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "SPBC16D10.04c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "Q9URU2", "SPBC16D10.04c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c" ] }, "reaction_10729498": { "compartment": "compartment_7660", "id": "reaction_10729498", "reactome": "R-SPO-69116", "name": "Formation of Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729491" ], "products": [ "species_10729495" ], "modifiers": [ [ "species_10729489", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04" ] }, "reaction_10729508": { "compartment": "compartment_7660", "id": "reaction_10729508", "reactome": "R-SPO-69140", "name": "RPA binds to the Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729504", "species_10729500" ], "products": [ "species_10729506" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c" ] }, "reaction_10729531": { "compartment": "compartment_7660", "id": "reaction_10729531", "reactome": "R-SPO-69152", "name": "Removal of remaining Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729519" ], "products": [ "species_10729523" ], "modifiers": [ [ "species_10729528", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "SPAC3G6.06c" ] }, "reaction_10729521": { "compartment": "compartment_7660", "id": "reaction_10729521", "reactome": "R-SPO-69144", "name": "Removal of RNA primer and dissociation of RPA and Dna2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729515" ], "products": [ "species_418075", "species_29626", "species_418076", "species_10729504", "species_10729519", "species_164121", "species_10729513" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "Q9URU2", "SPBC16D10.04c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "SPBC16D10.04c" ] }, "reaction_10729452": { "compartment": "compartment_7660", "id": "reaction_10729452", "reactome": "R-SPO-69053", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729371", "species_10729448" ], "products": [ "species_10729450" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c" ] }, "reaction_10754222": { "compartment": "compartment_70101", "id": "reaction_10754222", "reactome": "R-SPO-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754218", "species_10754213" ], "products": [ "species_10754220" ], "modifiers": [], "additional_components": [ "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c" ] }, "reaction_10754274": { "compartment": "compartment_70101", "id": "reaction_10754274", "reactome": "R-SPO-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729165", "species_10754220" ], "products": [ "species_10754271" ], "modifiers": [ [ "species_10754220", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c" ] }, "reaction_10754276": { "compartment": "compartment_70101", "id": "reaction_10754276", "reactome": "R-SPO-8854044", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754271" ], "products": [ "species_10754213", "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10732603": { "compartment": "compartment_5460", "id": "reaction_10732603", "reactome": "R-SPO-73918", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73871", "species_113559" ], "products": [ "species_29374", "species_73917" ], "modifiers": [ [ "species_10732600", "catalyst" ] ], "additional_components": [ "SPAC4F8.14c" ] }, "reaction_10732595": { "compartment": "compartment_5460", "id": "reaction_10732595", "reactome": "R-SPO-73912", "name": "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73909", "species_29362", "species_113529" ], "products": [ "species_73911", "species_113526" ], "modifiers": [ [ "species_10732592", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10736725": { "compartment": "compartment_7660", "id": "reaction_10736725", "reactome": "R-SPO-199839", "name": "AKT can phosphorylate RSK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10736698" ], "products": [ "species_113582", "species_10736702" ], "modifiers": [ [ "species_10736722", "catalyst" ] ], "additional_components": [ "SPCC4G3.08", "SPCC4G3.08", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10756118": { "compartment": "compartment_70101", "id": "reaction_10756118", "reactome": "R-SPO-8948757", "name": "AKT phosphorylates MKRN1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741188" ], "products": [ "species_29370", "species_10756116" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "O74463", "SPCC1739.01", "P41000", "SPAC3A11.02", "O74463", "SPCC1739.01", "P41000", "SPAC3A11.02", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10743069": { "compartment": "compartment_70101", "id": "reaction_10743069", "reactome": "R-SPO-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737088", "species_179856" ], "products": [ "species_10743067" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_179856", "Q12701", "SPCC576.15c" ] }, "reaction_10752710": { "compartment": "compartment_70101", "id": "reaction_10752710", "reactome": "R-SPO-6807206", "name": "USP13 and OTUD3 deubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752707", "species_29356" ], "products": [ "species_10736691", "species_10729165" ], "modifiers": [ [ "species_10750094", "catalyst" ] ], "additional_components": [ "SPBC609.02", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC6B1.06c" ] }, "reaction_10752676": { "compartment": "compartment_70101", "id": "reaction_10752676", "reactome": "R-SPO-6807105", "name": "Monoubiquitinated PTEN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752670" ], "products": [ "species_10752674" ], "modifiers": [], "additional_components": [ "SPBC609.02", "SPBC609.02" ] }, "reaction_10753807": { "compartment": "compartment_70101", "id": "reaction_10753807", "reactome": "R-SPO-8850992", "name": "Proteasome degrades polyubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753805" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "O94526", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10753445": { "compartment": "compartment_70101", "id": "reaction_10753445", "reactome": "R-SPO-6811504", "name": "AKT1 dephosphorylation by PP2A-B56-beta,gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736495", "species_29356" ], "products": [ "species_10738388", "species_29372" ], "modifiers": [ [ "species_10753440", "catalyst" ], [ "species_1806240", "inhibitor" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10428", "SPCC188.02", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "P78759", "SPAC6F12.12" ] }, "reaction_10752688": { "compartment": "compartment_7660", "id": "reaction_10752688", "reactome": "R-SPO-6807126", "name": "Deubiquitinated PTEN translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752683" ], "products": [ "species_10736691" ], "modifiers": [], "additional_components": [ "SPBC609.02", "SPBC609.02" ] }, "reaction_10736540": { "compartment": "compartment_876", "id": "reaction_10736540", "reactome": "R-SPO-198314", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10736518" ], "products": [ "species_29370", "species_10736537" ], "modifiers": [ [ "species_10736518", "catalyst" ], [ "species_112275", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10736556": { "compartment": "compartment_70101", "id": "reaction_10736556", "reactome": "R-SPO-198609", "name": "AKT phosphorylates TSC2, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735151" ], "products": [ "species_29370", "species_10736554" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "SPAC630.13c", "SPAC630.13c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10753795": { "compartment": "compartment_70101", "id": "reaction_10753795", "reactome": "R-SPO-8850945", "name": "Casein kinase II phosphorylates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_113592" ], "products": [ "species_10753793", "species_29370" ], "modifiers": [ [ "species_10743403", "catalyst" ] ], "additional_components": [ "SPBC609.02", "SPBC609.02", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11" ] }, "reaction_10756085": { "compartment": "compartment_13231", "id": "reaction_10756085", "reactome": "R-SPO-8944457", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756078" ], "products": [ "species_10756076" ], "modifiers": [], "additional_components": [ "SPAC31G5.12c", "SPAC31G5.12c" ] }, "reaction_10752681": { "compartment": "compartment_70101", "id": "reaction_10752681", "reactome": "R-SPO-6807106", "name": "PTEN undergoes monoubiquitination", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_10729165" ], "products": [ "species_10752670" ], "modifiers": [ [ "species_10752678", "catalyst" ] ], "additional_components": [ "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC609.02", "Q9UTG2", "SPAC1805.15c", "O14064", "SPCC962.02c", "Q92462", "SPAC11G7.02", "O14326", "SPBC16E9.11c" ] }, "reaction_10736552": { "compartment": "compartment_70101", "id": "reaction_10736552", "reactome": "R-SPO-198599", "name": "AKT phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736545", "species_113592" ], "products": [ "species_29370", "species_10736549" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10756121": { "compartment": "compartment_70101", "id": "reaction_10756121", "reactome": "R-SPO-8948775", "name": "MKRN1 polyubiquitinates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_10729165" ], "products": [ "species_10752707" ], "modifiers": [ [ "species_10756116", "catalyst" ] ], "additional_components": [ "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC609.02", "O74463", "SPCC1739.01", "P41000", "SPAC3A11.02" ] }, "reaction_10752686": { "compartment": "compartment_7660", "id": "reaction_10752686", "reactome": "R-SPO-6807118", "name": "USP7 deubiquitinates monoubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752674", "species_113518" ], "products": [ "species_10752683", "species_10729044" ], "modifiers": [ [ "species_10747825", "catalyst" ] ], "additional_components": [ "SPBC609.02", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPCC188.08c" ] }, "reaction_10752704": { "compartment": "compartment_70101", "id": "reaction_10752704", "reactome": "R-SPO-6807134", "name": "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_10729165" ], "products": [ "species_10752691" ], "modifiers": [ [ "species_10752701", "catalyst" ] ], "additional_components": [ "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC609.02", "Q9UTG2", "SPAC1805.15c", "O14064", "SPCC962.02c", "Q92462", "SPAC11G7.02", "O14326", "SPBC16E9.11c" ] }, "reaction_10757421": { "compartment": "compartment_7660", "id": "reaction_10757421", "reactome": "R-SPO-9632910", "name": "ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744302" ], "products": [ "species_10736630" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "P27638", "SPAC31G5.09c" ] }, "reaction_10757419": { "compartment": "compartment_876", "id": "reaction_10757419", "reactome": "R-SPO-9632858", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10757406" ], "products": [ "species_29370", "species_10757416" ], "modifiers": [ [ "species_10757406", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "species_179838", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_179838", "P36582", "SPAC17G8.14c", "Q12701", "SPCC576.15c", "P36583", "SPBC12D12.04c", "species_179838", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c" ] }, "reaction_10744869": { "compartment": "compartment_7660", "id": "reaction_10744869", "reactome": "R-SPO-4570467", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744858" ], "products": [ "species_10743639", "species_10744867" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC23G3.06", "SPAC30D11.13", "O13351", "SPBC365.06", "Q9P7S7", "SPAC23G3.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744879": { "compartment": "compartment_7660", "id": "reaction_10744879", "reactome": "R-SPO-4570493", "name": "RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10730960" ], "products": [ "species_10743639", "species_10744877" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC3H8.09c", "SPAC30D11.13", "O13351", "SPBC365.06", "Q10145", "SPAC3H8.09c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10738944": { "compartment": "compartment_7660", "id": "reaction_10738944", "reactome": "R-SPO-427527", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10737547" ], "products": [ "species_77502", "species_10732938" ], "modifiers": [ [ "species_10738938", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "O94640", "SPBC16D10.07c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10257", "SPAC56F8.09", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c" ] }, "reaction_10738941": { "compartment": "compartment_7660", "id": "reaction_10738941", "reactome": "R-SPO-427514", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738924", "species_427523" ], "products": [ "species_427498", "species_427497", "species_10737547" ], "modifiers": [ [ "species_10738938", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "O94640", "SPBC16D10.07c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10257", "SPAC56F8.09", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c" ] }, "reaction_10735753": { "compartment": "compartment_7660", "id": "reaction_10735753", "reactome": "R-SPO-176956", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735739", "species_10735734", "species_10735749", "species_10735744" ], "products": [ "species_10735751" ], "modifiers": [], "additional_components": [ "SPBC725.13c", "SPBP23A10.09", "SPBP4H10.21c", "SPAC227.16c", "Q9UTC3", "SPAC227.16c", "O94329", "SPBC725.13c", "Q9P7X6", "SPBP23A10.09", "Q9P7C8", "SPBP4H10.21c" ] }, "reaction_10733255": { "compartment": "compartment_7660", "id": "reaction_10733255", "reactome": "R-SPO-75809", "name": "Phosphorylation of Cdc25C at Ser216 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732945", "species_29358" ], "products": [ "species_113582", "species_10732948" ], "modifiers": [ [ "species_10729617", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC14C4.03" ] }, "reaction_10757028": { "compartment": "compartment_70101", "id": "reaction_10757028", "reactome": "R-SPO-9029987", "name": "p-S216-CDC25C translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732948" ], "products": [ "species_10732952" ], "modifiers": [], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05" ] }, "reaction_10752429": { "compartment": "compartment_984", "id": "reaction_10752429", "reactome": "R-SPO-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752417" ], "products": [ "species_10752427" ], "modifiers": [], "additional_components": [ "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14098", "SPAC2F3.15", "O13864", "SPAC1B1.03c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "P05933", "SPAC3A12.14", "O94395", "SPCC126.02c", "Q9UUJ1", "SPAC11H11.06", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "O14008", "SPAC29A4.05", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "P27638", "SPAC31G5.09c", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "P32834", "SPAC26A3.01", "O74374", "SPBC32F12.10", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O43062", "SPBC4C3.09", "O13907", "SPAC22A12.16", "O94544", "SPCC1322.05c", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13", "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14098", "SPAC2F3.15", "O13864", "SPAC1B1.03c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "P05933", "SPAC3A12.14", "O94395", "SPCC126.02c", "Q9UUJ1", "SPAC11H11.06", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "O14008", "SPAC29A4.05", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "P27638", "SPAC31G5.09c", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "P32834", "SPAC26A3.01", "O74374", "SPBC32F12.10", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O43062", "SPBC4C3.09", "O13907", "SPAC22A12.16", "O94544", "SPCC1322.05c", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13" ] }, "reaction_10752526": { "compartment": "compartment_984", "id": "reaction_10752526", "reactome": "R-SPO-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752522", "species_181015" ], "products": [ "species_10752524" ], "modifiers": [], "additional_components": [ "SPAC57A10.09c", "P87057", "SPAC57A10.09c", "species_181015" ] }, "reaction_10752168": { "compartment": "compartment_6799351", "id": "reaction_10752168", "reactome": "R-SPO-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752152" ], "products": [ "species_10752166" ], "modifiers": [], "additional_components": [ "O13995", "SPAC25B8.01", "Q9P380", "SPBC13A2.04c", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O94296", "SPBC887.12", "Q9HFE5", "SPBP16F5.07", "Q9US20", "SPAC1851.02", "O59826", "SPCC965.06", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O59823", "SPCC965.03", "Q1MTQ5", "SPBC1773.11c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "O59715", "SPBC3B8.07c", "O42901", "SPBC119.09c", "Q09891", "SPAC24B11.12c", "O13995", "SPAC25B8.01", "Q9P380", "SPBC13A2.04c", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O94296", "SPBC887.12", "Q9HFE5", "SPBP16F5.07", "Q9US20", "SPAC1851.02", "O59826", "SPCC965.06", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O59823", "SPCC965.03", "Q1MTQ5", "SPBC1773.11c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "O59715", "SPBC3B8.07c", "O42901", "SPBC119.09c", "Q09891", "SPAC24B11.12c" ] }, "reaction_10741378": { "compartment": "compartment_70101", "id": "reaction_10741378", "reactome": "R-SPO-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741318", "species_113592", "species_10741312" ], "products": [ "species_10741349", "species_111294", "species_76577", "species_10741310" ], "modifiers": [ [ "species_10741318", "catalyst" ] ], "additional_components": [ "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q09760", "SPAC24H6.03", "P10505", "SPAC17C9.01c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O00102", "SPBP16F5.04", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q09760", "SPAC24H6.03", "P10505", "SPAC17C9.01c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01" ] }, "reaction_10752530": { "compartment": "compartment_984", "id": "reaction_10752530", "reactome": "R-SPO-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752522", "species_166005" ], "products": [ "species_10752528" ], "modifiers": [], "additional_components": [ "SPAC57A10.09c", "P87057", "SPAC57A10.09c", "species_166005" ] }, "reaction_10742867": { "compartment": "compartment_70101", "id": "reaction_10742867", "reactome": "R-SPO-2029456", "name": "RAC1 and CDC42 activate PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738332", "species_10738231" ], "products": [ "species_10742858", "species_10738330" ], "modifiers": [], "additional_components": [ "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "SPBC1604.14c" ] }, "reaction_10752267": { "compartment": "compartment_6800424", "id": "reaction_10752267", "reactome": "R-SPO-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752257" ], "products": [ "species_10752265" ], "modifiers": [], "additional_components": [ "P50515", "SPAC1B3.14", "Q9UUF7", "SPBC146.14c", "Q9P3W4", "SPAC458.04c", "Q9Y7J5", "SPBC1778.09", "Q9C0Y4", "SPAPB24D3.10c", "Q09914", "SPAC1F7.04", "O13742", "SPAC16E8.07c", "O13766", "SPAC17A5.04c", "O94323", "SPBC725.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q9C0W7", "SPBC691.03c", "Q9UR05", "SPAC926.07c", "P50515", "SPAC1B3.14", "Q9UUF7", "SPBC146.14c", "Q9P3W4", "SPAC458.04c", "Q9Y7J5", "SPBC1778.09", "Q9C0Y4", "SPAPB24D3.10c", "Q09914", "SPAC1F7.04", "O13742", "SPAC16E8.07c", "O13766", "SPAC17A5.04c", "O94323", "SPBC725.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q9C0W7", "SPBC691.03c", "Q9UR05", "SPAC926.07c" ] }, "reaction_10743526": { "compartment": "compartment_70101", "id": "reaction_10743526", "reactome": "R-SPO-2730835", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10737102" ], "products": [ "species_10743524", "species_29370" ], "modifiers": [], "additional_components": [ "species_112275", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "P36582", "SPAC17G8.14c" ] }, "reaction_10741650": { "compartment": "compartment_70101", "id": "reaction_10741650", "reactome": "R-SPO-1250280", "name": "ROS oxidize thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1250243", "species_10732350" ], "products": [ "species_10732348" ], "modifiers": [], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c" ] }, "reaction_10751591": { "compartment": "compartment_6800173", "id": "reaction_10751591", "reactome": "R-SPO-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751567" ], "products": [ "species_10751589" ], "modifiers": [], "additional_components": [ "Q10182", "SPAC3F10.07c", "Q09190", "SPAC1556.04c", "P32834", "SPAC26A3.01", "O74374", "SPBC32F12.10", "O13728", "SPAC15A10.08", "O14254", "SPAC6G10.08", "O94544", "SPCC1322.05c", "Q9P7E8", "SPAPJ760.02c", "O13986", "SPAC26H5.04", "Q10166", "SPAC26A3.11", "Q10182", "SPAC3F10.07c", "P32834", "SPAC26A3.01", "Q09190", "SPAC1556.04c", "O74374", "SPBC32F12.10", "O13728", "SPAC15A10.08", "O14254", "SPAC6G10.08", "O94544", "SPCC1322.05c", "Q9P7E8", "SPAPJ760.02c", "O13986", "SPAC26H5.04", "Q10166", "SPAC26A3.11" ] }, "reaction_10741390": { "compartment": "compartment_17957", "id": "reaction_10741390", "reactome": "R-SPO-983158", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983034" ], "products": [ "species_983033", "species_8943716" ], "modifiers": [ [ "species_10741385", "catalyst" ] ], "additional_components": [ "SPBC1921.05" ] }, "reaction_10737119": { "compartment": "compartment_876", "id": "reaction_10737119", "reactome": "R-SPO-202222", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10737102" ], "products": [ "species_29370", "species_10737116" ], "modifiers": [ [ "species_10737090", "catalyst" ] ], "additional_components": [ "species_112275", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "P36582", "SPAC17G8.14c", "species_202247", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10751415": { "compartment": "compartment_6798757", "id": "reaction_10751415", "reactome": "R-SPO-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751383" ], "products": [ "species_10751413" ], "modifiers": [], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q92356", "SPAC6G9.11", "O59866", "SPCC338.15", "O94296", "SPBC887.12", "O60119", "SPBC16G5.05c", "P50515", "SPAC1B3.14", "Q9USS6", "SPBC4.06", "Q9UT43", "SPBC887.12", "Q1MTQ5", "SPBC1773.11c", "Q8TFH3", "SPAPB17E12.11", "P17609", "SPAC9E9.07c", "O74786", "SPBC26H8.02c", "Q9URX4", "SPAC30D11.01c", "O13876", "SPAC1B3.11c", "Q09901", "SPAC30D11.01c", "O74559", "SPCC970.06", "Q9C0Y4", "SPAPB24D3.10c", "Q92356", "SPAC6G9.11", "O59866", "SPCC338.15", "O94296", "SPBC887.12", "O60119", "SPBC16G5.05c", "P50515", "SPAC1B3.14", "Q9USS6", "SPBC4.06", "Q9UT43", "SPBC887.12", "Q1MTQ5", "SPBC1773.11c", "Q8TFH3", "SPAPB17E12.11", "P17609", "SPAC9E9.07c", "O74786", "SPBC26H8.02c", "Q9URX4", "SPAC30D11.01c", "O13876", "SPAC1B3.11c", "Q09901", "SPAC30D11.01c", "O74559", "SPCC970.06" ] }, "reaction_10741351": { "compartment": "compartment_70101", "id": "reaction_10741351", "reactome": "R-SPO-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741349" ], "products": [ "species_983123", "species_10741221" ], "modifiers": [], "additional_components": [ "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10743820": { "compartment": "compartment_70101", "id": "reaction_10743820", "reactome": "R-SPO-3204303", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_874088", "species_10743816" ], "products": [ "species_10743818" ], "modifiers": [], "additional_components": [ "SPAC13C5.07", "Q09683", "SPAC13C5.07", "species_874088" ] }, "reaction_10745986": { "compartment": "compartment_876", "id": "reaction_10745986", "reactome": "R-SPO-5607734", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745398", "species_112275" ], "products": [ "species_10745984" ], "modifiers": [], "additional_components": [ "SPBC12D12.04c", "P36583", "SPBC12D12.04c", "species_112275" ] }, "reaction_10757837": { "compartment": "compartment_70101", "id": "reaction_10757837", "reactome": "R-SPO-9690461", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757816", "species_9678991" ], "products": [ "species_10757835" ], "modifiers": [], "additional_components": [ "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c", "species_9678991", "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c" ] }, "reaction_10741380": { "compartment": "compartment_70101", "id": "reaction_10741380", "reactome": "R-SPO-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741221", "species_10741312", "species_983035" ], "products": [ "species_10741314" ], "modifiers": [], "additional_components": [ "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O00102", "SPBP16F5.04", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9Y818", "SPBC1105.09", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q9P7R4", "SPBC211.07c", "Q09760", "SPAC24H6.03", "P23566", "SPAC18B11.07c", "P10505", "SPAC17C9.01c", "O00103", "SPCC1259.15c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O00102", "SPBP16F5.04", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "O74983", "SPCC338.05c", "Q09855", "SPAC29E6.01", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O94609", "SPBC1604.21c", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q9UTN8", "SPAC1250.03", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "O42646", "SPAC10F6.05c", "Q9P4W7", "SPAC959.09c", "O74549", "SPCC777.10c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01" ] }, "reaction_10751953": { "compartment": "compartment_1462052", "id": "reaction_10751953", "reactome": "R-SPO-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751817" ], "products": [ "species_10751951" ], "modifiers": [], "additional_components": [ "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "O42842", "SPAC23A1.03", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "Q9HGM8", "SPBC543.03c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "O14242", "SPAC6F6.11c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "O94395", "SPCC126.02c", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O74335", "SPBC17F3.01c", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O94466", "SPBC23G7.08c", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "Q10305", "SPAC22H10.12c", "O43062", "SPBC4C3.09", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13", "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "O42842", "SPAC23A1.03", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "Q9HGM8", "SPBC543.03c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "O14242", "SPAC6F6.11c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "O94395", "SPCC126.02c", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O74335", "SPBC17F3.01c", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O94466", "SPBC23G7.08c", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "Q10305", "SPAC22H10.12c", "O43062", "SPBC4C3.09", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13" ] }, "reaction_10738399": { "compartment": "compartment_70101", "id": "reaction_10738399", "reactome": "R-SPO-390329", "name": "Dephosphorylation of AKT by PP2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736505", "species_29356" ], "products": [ "species_10738396", "species_29372" ], "modifiers": [ [ "species_10738274", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10428", "SPCC188.02", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "P78759", "SPAC6F12.12" ] }, "reaction_10741612": { "compartment": "compartment_70101", "id": "reaction_10741612", "reactome": "R-SPO-1247960", "name": "Activation of p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741601" ], "products": [ "species_29370", "species_10741609" ], "modifiers": [ [ "species_10739738", "catalyst" ] ], "additional_components": [ "Q09892", "SPAC24B11.06c", "Q09892", "SPAC24B11.06c", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c" ] }, "reaction_10741353": { "compartment": "compartment_70101", "id": "reaction_10741353", "reactome": "R-SPO-983150", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983123" ], "products": [ "species_983032", "species_983036", "species_10729165", "species_8942986" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10742956": { "compartment": "compartment_161320", "id": "reaction_10742956", "reactome": "R-SPO-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10742951", "catalyst" ] ], "additional_components": [ "SPAC26A3.01" ] }, "reaction_10751977": { "compartment": "compartment_6799371", "id": "reaction_10751977", "reactome": "R-SPO-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751969" ], "products": [ "species_10751975" ], "modifiers": [], "additional_components": [ "P32834", "SPAC26A3.01", "O14242", "SPAC6F6.11c", "O13728", "SPAC15A10.08", "Q10166", "SPAC26A3.11", "O13864", "SPAC1B1.03c", "O13986", "SPAC26H5.04", "Q10066", "SPAC3H1.07", "P32834", "SPAC26A3.01", "O13728", "SPAC15A10.08", "O14242", "SPAC6F6.11c", "O13986", "SPAC26H5.04", "Q10166", "SPAC26A3.11", "O13864", "SPAC1B1.03c", "Q10066", "SPAC3H1.07" ] }, "reaction_10751653": { "compartment": "compartment_6799713", "id": "reaction_10751653", "reactome": "R-SPO-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751641" ], "products": [ "species_10751651" ], "modifiers": [], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q09706", "SPAC2F7.16c", "Q92356", "SPAC6G9.11", "O94296", "SPBC887.12", "Q9UR05", "SPAC926.07c", "P50515", "SPAC1B3.14", "O59826", "SPCC965.06", "Q9UUF7", "SPBC146.14c", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q09891", "SPAC24B11.12c", "Q9C0Y4", "SPAPB24D3.10c", "Q09706", "SPAC2F7.16c", "Q92356", "SPAC6G9.11", "O94296", "SPBC887.12", "Q9UR05", "SPAC926.07c", "P50515", "SPAC1B3.14", "O59826", "SPCC965.06", "Q9UUF7", "SPBC146.14c", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q09891", "SPAC24B11.12c" ] }, "reaction_10745990": { "compartment": "compartment_876", "id": "reaction_10745990", "reactome": "R-SPO-5607746", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745984" ], "products": [ "species_10745988" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "species_112275", "P36583", "SPBC12D12.04c", "species_112275" ] }, "reaction_10741530": { "compartment": "compartment_1222693", "id": "reaction_10741530", "reactome": "R-SPO-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10741527", "catalyst" ] ], "additional_components": [ "P50515", "SPAC1B3.14", "O43046", "SPBC3B9.18c", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O59823", "SPCC965.03", "O14046", "SPAC2C4.13", "O13742", "SPAC16E8.07c", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q69Z14", "SPBC1685.16", "Q9HDW6", "SPAPB2B4.05" ] }, "reaction_10741321": { "compartment": "compartment_70101", "id": "reaction_10741321", "reactome": "R-SPO-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741314" ], "products": [ "species_10741318", "species_111294", "species_76577", "species_10741310" ], "modifiers": [ [ "species_10741221", "catalyst" ] ], "additional_components": [ "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9Y818", "SPBC1105.09", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q9P7R4", "SPBC211.07c", "Q09760", "SPAC24H6.03", "P23566", "SPAC18B11.07c", "P10505", "SPAC17C9.01c", "O00103", "SPCC1259.15c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O00102", "SPBP16F5.04", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "O74983", "SPCC338.05c", "Q09855", "SPAC29E6.01", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O94609", "SPBC1604.21c", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q9UTN8", "SPAC1250.03", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "O42646", "SPAC10F6.05c", "Q9P4W7", "SPAC959.09c", "O74549", "SPCC777.10c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q09760", "SPAC24H6.03", "P10505", "SPAC17C9.01c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10740329": { "compartment": "compartment_70101", "id": "reaction_10740329", "reactome": "R-SPO-874087", "name": "SGT1 binds HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740325", "species_10740323" ], "products": [ "species_10740327" ], "modifiers": [], "additional_components": [ "SPAC926.04c", "SPBC36.12c", "P41887", "SPAC926.04c", "O59709", "SPBC36.12c" ] }, "reaction_10741337": { "compartment": "compartment_17957", "id": "reaction_10741337", "reactome": "R-SPO-983144", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983032", "species_113592", "species_29356" ], "products": [ "species_983034", "species_29370", "species_29372" ], "modifiers": [ [ "species_10741334", "catalyst" ] ], "additional_components": [ "P78966", "SPBC25B2.02c" ] }, "reaction_10742881": { "compartment": "compartment_876", "id": "reaction_10742881", "reactome": "R-SPO-2029471", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_29356" ], "products": [ "species_264618", "species_1602448" ], "modifiers": [ [ "species_10742876", "catalyst" ] ], "additional_components": [ "SPAC2F7.16c" ] }, "reaction_10737092": { "compartment": "compartment_70101", "id": "reaction_10737092", "reactome": "R-SPO-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737088", "species_202277" ], "products": [ "species_10737090" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_202247", "species_179838", "species_202247", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10752099": { "compartment": "compartment_1470028", "id": "reaction_10752099", "reactome": "R-SPO-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752055" ], "products": [ "species_10752097" ], "modifiers": [], "additional_components": [ "Q9UT70", "SPAC3G9.16c", "O74762", "SPBC17D11.07c", "O74557", "SPCC970.03", "Q9UUJ1", "SPAC11H11.06", "Q9P3A7", "SPAC1565.08", "P27638", "SPAC31G5.09c", "P05219", "SPBC26H8.07c", "O74490", "SPCC1442.17c", "O74492", "SPCC285.04", "Q9URZ0", "SPAC869.07c", "P78921", "SPBC337.05c", "Q10305", "SPAC22H10.12c", "O74498", "SPCC285.11", "P36621", "SPCC306.09c", "O74335", "SPBC17F3.01c", "O13907", "SPAC22A12.16", "P36583", "SPBC12D12.04c", "O14344", "SPBC2F12.14c", "P15258", "SPBC21.05c", "Q10147", "SPAC1D4.04", "O13290", "SPAC1093.06c", "Q09184", "SPAC23H4.09", "Q10066", "SPAC3H1.07", "Q9UUB5", "SPBC409.09c", "Q9UT70", "SPAC3G9.16c", "O74762", "SPBC17D11.07c", "O74557", "SPCC970.03", "Q9UUJ1", "SPAC11H11.06", "Q9P3A7", "SPAC1565.08", "P27638", "SPAC31G5.09c", "P05219", "SPBC26H8.07c", "O74490", "SPCC1442.17c", "O74492", "SPCC285.04", "Q9URZ0", "SPAC869.07c", "P78921", "SPBC337.05c", "Q10305", "SPAC22H10.12c", "O74498", "SPCC285.11", "P36621", "SPCC306.09c", "O74335", "SPBC17F3.01c", "O13907", "SPAC22A12.16", "P36583", "SPBC12D12.04c", "O14344", "SPBC2F12.14c", "P15258", "SPBC21.05c", "Q10147", "SPAC1D4.04", "O13290", "SPAC1093.06c", "Q09184", "SPAC23H4.09", "Q10066", "SPAC3H1.07", "Q9UUB5", "SPBC409.09c" ] }, "reaction_10741648": { "compartment": "compartment_70101", "id": "reaction_10741648", "reactome": "R-SPO-1250264", "name": "TXNIP binds reduced thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741644", "species_10732350" ], "products": [ "species_10741646" ], "modifiers": [], "additional_components": [ "Q09889", "SPCC584.15c", "O60150", "SPCC584.15c", "Q8WZK5", "SPCC584.15c", "Q10347", "SPCC584.15c", "Q09729", "SPCC584.15c", "O74798", "SPCC584.15c", "SPBC12D12.07c", "Q09889", "SPCC584.15c", "O60150", "SPCC584.15c", "Q8WZK5", "SPCC584.15c", "Q10347", "SPCC584.15c", "Q09729", "SPCC584.15c", "O94504", "SPBC12D12.07c", "O74798", "SPCC584.15c" ] }, "reaction_10742887": { "compartment": "compartment_70101", "id": "reaction_10742887", "reactome": "R-SPO-2029473", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737182", "species_10742885" ], "products": [ "species_10742765" ], "modifiers": [], "additional_components": [ "species_113592", "O60054", "SPBC56F2.03", "P10989", "SPBC32H8.12c", "P78774", "SPBC14C8.06", "Q10316", "SPAC17G8.04c", "Q9UUJ1", "SPAC11H11.06", "Q92352", "SPAC6G9.07c", "O60054", "SPBC56F2.03", "species_29370", "species_113592", "O14241", "SPAC6F6.10c", "P32390", "SPAC630.03", "Q9Y7J4", "SPBC1778.08c", "P10989", "SPBC32H8.12c", "P78774", "SPBC14C8.06", "Q10316", "SPAC17G8.04c", "Q9UUJ1", "SPAC11H11.06", "Q92352", "SPAC6G9.07c", "O14241", "SPAC6F6.10c", "species_113592", "O60054", "SPBC56F2.03", "P32390", "SPAC630.03", "Q9Y7J4", "SPBC1778.08c", "P10989", "SPBC32H8.12c" ] }, "reaction_10742865": { "compartment": "compartment_70101", "id": "reaction_10742865", "reactome": "R-SPO-2029454", "name": "Autophosphorylation of PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742858", "species_113592" ], "products": [ "species_29370", "species_10742862", "species_10738231" ], "modifiers": [ [ "species_10738330", "catalyst" ] ], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "SPBC1604.14c" ] }, "reaction_10741375": { "compartment": "compartment_70101", "id": "reaction_10741375", "reactome": "R-SPO-983153", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10729165", "species_29926", "species_10741367" ], "products": [ "species_10741369", "species_111294", "species_76577", "species_29926" ], "modifiers": [ [ "species_10741367", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O43069", "SPBC6B1.05c", "Q09765", "SPAC24H6.12c", "O94609", "SPBC1604.21c", "O43069", "SPBC6B1.05c", "P0CH07", "SPAC1805.12c", "Q09765", "SPAC24H6.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O43069", "SPBC6B1.05c", "Q09765", "SPAC24H6.12c", "O94609", "SPBC1604.21c" ] }, "reaction_10738619": { "compartment": "compartment_70101", "id": "reaction_10738619", "reactome": "R-SPO-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10738616", "catalyst" ] ], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01" ] }, "reaction_10743556": { "compartment": "compartment_70101", "id": "reaction_10743556", "reactome": "R-SPO-2730867", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743536" ], "products": [ "species_10743554" ], "modifiers": [], "additional_components": [ "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q12705", "SPBP4H10.04", "CHEBI:29034", "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "Q12705", "SPBP4H10.04", "O14008", "SPAC29A4.05", "CHEBI:29034" ] }, "reaction_10737443": { "compartment": "compartment_12045", "id": "reaction_10737443", "reactome": "R-SPO-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737349", "species_10737439" ], "products": [ "species_10737441" ], "modifiers": [], "additional_components": [ "Q01475", "SPBC31F10.06c", "species_29438", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q01475", "SPBC31F10.06c", "Q9USS7", "SPBC4.03c", "species_29438" ] }, "reaction_10741491": { "compartment": "compartment_70101", "id": "reaction_10741491", "reactome": "R-SPO-1168373", "name": "PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734514", "species_74016", "species_33625", "species_114519" ], "products": [ "species_10734538" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10751533": { "compartment": "compartment_876", "id": "reaction_10751533", "reactome": "R-SPO-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751485" ], "products": [ "species_10751531" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "Q9HDY0", "SPAPB1A10.10c", "Q9P3W4", "SPAC458.04c", "Q09914", "SPAC1F7.04", "Q10133", "SPAC16.01", "P17608", "SPAC4C5.02c", "Q9C0W7", "SPBC691.03c", "Q9HE04", "SPAC20H4.11c", "O94655", "SPBC405.04c", "Q9UUF7", "SPBC146.14c", "Q9USX1", "SPBC1921.05", "O13742", "SPAC16E8.07c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "O42901", "SPBC119.09c", "Q10201", "SPBC17D1.07c", "Q9HDY0", "SPAPB1A10.10c", "Q9P3W4", "SPAC458.04c", "Q09914", "SPAC1F7.04", "Q10133", "SPAC16.01", "P17608", "SPAC4C5.02c", "Q9C0W7", "SPBC691.03c", "Q9HE04", "SPAC20H4.11c", "O94655", "SPBC405.04c", "Q9UUF7", "SPBC146.14c", "Q9USX1", "SPBC1921.05", "O13742", "SPAC16E8.07c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "O42901", "SPBC119.09c" ] }, "reaction_10742874": { "compartment": "compartment_876", "id": "reaction_10742874", "reactome": "R-SPO-2029468", "name": "Conversion of PA into DAG by PAP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_29372", "species_112275" ], "modifiers": [ [ "species_10742869", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10737129": { "compartment": "compartment_70101", "id": "reaction_10737129", "reactome": "R-SPO-202328", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736928", "species_112275" ], "products": [ "species_10737127" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "P36582", "SPAC17G8.14c" ] }, "reaction_10741395": { "compartment": "compartment_70101", "id": "reaction_10741395", "reactome": "R-SPO-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983036" ], "products": [ "species_983032", "species_8942986" ], "modifiers": [ [ "species_10741392", "catalyst" ] ], "additional_components": [ "SPBC1921.05" ] }, "reaction_10741372": { "compartment": "compartment_70101", "id": "reaction_10741372", "reactome": "R-SPO-983152", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741369", "species_10741310" ], "products": [ "species_10741312", "species_10741367" ], "modifiers": [ [ "species_10741310", "catalyst" ] ], "additional_components": [ "O43069", "SPBC6B1.05c", "P0CH07", "SPAC1805.12c", "Q09765", "SPAC24H6.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O00102", "SPBP16F5.04", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O43069", "SPBC6B1.05c", "Q09765", "SPAC24H6.12c", "O94609", "SPBC1604.21c", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04" ] }, "reaction_10745417": { "compartment": "compartment_70101", "id": "reaction_10745417", "reactome": "R-SPO-5218813", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745410", "species_74016", "species_112275" ], "products": [ "species_10745415" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "species_74016", "P36582", "SPAC17G8.14c" ] }, "reaction_10737056": { "compartment": "compartment_70101", "id": "reaction_10737056", "reactome": "R-SPO-202127", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10737053", "catalyst" ], [ "species_5693375", "inhibitor" ] ], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "P36587", "SPBC29A10.01", "species_29870" ] }, "reaction_10737080": { "compartment": "compartment_70101", "id": "reaction_10737080", "reactome": "R-SPO-202137", "name": "AKT1 binds eNOS complex via HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737016", "species_10736495" ], "products": [ "species_10737024" ], "modifiers": [], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "P41887", "SPAC926.04c", "species_74016", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "O14008", "SPAC29A4.05", "P36587", "SPBC29A10.01", "species_113596", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "species_442320", "Q10364", "SPAC22E12.14c", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "P41887", "SPAC926.04c", "species_74016", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "O14008", "SPAC29A4.05", "P36587", "SPBC29A10.01", "P50530", "SPAC1B9.02c", "species_113596" ] }, "reaction_10745428": { "compartment": "compartment_876", "id": "reaction_10745428", "reactome": "R-SPO-5218821", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10745425" ], "products": [ "species_29370", "species_10745378" ], "modifiers": [ [ "species_10733716", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "SPCC576.15c" ] }, "reaction_10737051": { "compartment": "compartment_70101", "id": "reaction_10737051", "reactome": "R-SPO-202111", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10737024" ], "products": [ "species_29370", "species_10737049" ], "modifiers": [], "additional_components": [ "species_442320", "Q10364", "SPAC22E12.14c", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "P41887", "SPAC926.04c", "species_74016", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "O14008", "SPAC29A4.05", "P36587", "SPBC29A10.01", "P50530", "SPAC1B9.02c", "species_113596", "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_29870", "P36587", "SPBC29A10.01" ] }, "reaction_10742175": { "compartment": "compartment_70101", "id": "reaction_10742175", "reactome": "R-SPO-1497784", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_10737049" ], "products": [ "species_10737053" ], "modifiers": [], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_29870", "P36587", "SPBC29A10.01", "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "P36587", "SPBC29A10.01", "species_29870" ] }, "reaction_10745434": { "compartment": "compartment_876", "id": "reaction_10745434", "reactome": "R-SPO-5218823", "name": "PKC phosphorylates sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738404", "species_113592" ], "products": [ "species_29370", "species_10745431" ], "modifiers": [ [ "species_10745415", "catalyst" ] ], "additional_components": [ "SPAC4A8.07c", "SPAC4A8.07c", "P36583", "SPBC12D12.04c", "species_112275", "species_74016", "P36582", "SPAC17G8.14c" ] }, "reaction_10745413": { "compartment": "compartment_70101", "id": "reaction_10745413", "reactome": "R-SPO-5218805", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745378", "species_113592" ], "products": [ "species_29370", "species_10745410" ], "modifiers": [ [ "species_10745378", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10756127": { "compartment": "compartment_70616", "id": "reaction_10756127", "reactome": "R-SPO-8949580", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735134" ], "products": [ "species_10756125" ], "modifiers": [], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10743814": { "compartment": "compartment_7660", "id": "reaction_10743814", "reactome": "R-SPO-3108212", "name": "SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743242", "species_10743647" ], "products": [ "species_10743639", "species_10743780" ], "modifiers": [ [ "species_10743811", "catalyst" ] ], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "Q92380", "SPCC4E9.01c", "O13351", "SPBC365.06", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "P53692", "SPCC5E4.06", "O13710", "SPAC14C4.02c", "Q6BDR8", "SPBC20F10.04c", "Q4PIR3", "SPAC16A10.06c", "Q9Y7U4", "SPCC645.04", "Q53EK2", "SPCC550.05" ] }, "reaction_10744821": { "compartment": "compartment_7660", "id": "reaction_10744821", "reactome": "R-SPO-4551648", "name": "SUMOylation of TDG with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10733857" ], "products": [ "species_10743639", "species_10744819" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPCC965.05c", "SPAC30D11.13", "O13351", "SPBC365.06", "O59825", "SPCC965.05c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744848": { "compartment": "compartment_7660", "id": "reaction_10744848", "reactome": "R-SPO-4568863", "name": "SUMOylation of RAD52 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733420", "species_10743647" ], "products": [ "species_10743639", "species_10744846" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC30D11.10", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P36592", "SPAC30D11.10", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744919": { "compartment": "compartment_7660", "id": "reaction_10744919", "reactome": "R-SPO-4570554", "name": "SUMOylation of MDC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744909", "species_10743647" ], "products": [ "species_10743639", "species_10744917" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPACUNK4.14", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O14079", "SPACUNK4.14", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744904": { "compartment": "compartment_7660", "id": "reaction_10744904", "reactome": "R-SPO-4570528", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744894", "species_10743647" ], "products": [ "species_10743639", "species_10744902" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPCC4G3.10c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P87235", "SPCC4G3.10c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10730240": { "compartment": "compartment_70101", "id": "reaction_10730240", "reactome": "R-SPO-71286", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_30401" ], "products": [ "species_70106", "species_71285", "species_29916" ], "modifiers": [ [ "species_10730237", "catalyst" ] ], "additional_components": [ "SPAC26A3.17c" ] }, "reaction_10753723": { "compartment": "compartment_12045", "id": "reaction_10753723", "reactome": "R-SPO-8848582", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848577", "species_200993" ], "products": [ "species_76194", "species_8848499" ], "modifiers": [ [ "species_10749964", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10753726": { "compartment": "compartment_12045", "id": "reaction_10753726", "reactome": "R-SPO-8848585", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30209", "species_200993" ], "products": [ "species_76194", "species_2534407" ], "modifiers": [ [ "species_10749964", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10749962": { "compartment": "compartment_12045", "id": "reaction_10749962", "reactome": "R-SPO-5696424", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696426", "species_192172" ], "products": [ "species_162743", "species_5696412" ], "modifiers": [ [ "species_10749959", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10734474": { "compartment": "compartment_7660", "id": "reaction_10734474", "reactome": "R-SPO-113504", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729371" ], "products": [ "species_113656", "species_10728742" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c" ] }, "reaction_10756722": { "compartment": "compartment_70101", "id": "reaction_10756722", "reactome": "R-SPO-9013024", "name": "RHOB binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756718", "species_10756713" ], "products": [ "species_10756720" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "P36583", "SPBC12D12.04c", "P78953", "SPCC4B3.15", "Q92356", "SPAC6G9.11", "O14188", "SPAC4F8.13c", "O74786", "SPBC26H8.02c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "O43027", "SPBC354.13", "Q10133", "SPAC16.01", "species_29438", "Q9P3B1", "SPAC1565.02c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "O74786", "SPBC26H8.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c" ] }, "reaction_10756711": { "compartment": "compartment_70101", "id": "reaction_10756711", "reactome": "R-SPO-9013021", "name": "GDIs block activation of RHOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756705", "species_10756703" ], "products": [ "species_10756709" ], "modifiers": [], "additional_components": [ "SPAC6F12.06", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O14224", "SPAC6F12.06" ] }, "reaction_10756716": { "compartment": "compartment_70101", "id": "reaction_10756716", "reactome": "R-SPO-9013022", "name": "RHOB GAPs stimulate RHOB GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756713", "species_29356" ], "products": [ "species_29372", "species_10756703" ], "modifiers": [ [ "species_10756508", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757839": { "compartment": "compartment_876", "id": "reaction_10757839", "reactome": "R-SPO-9690494", "name": "RHOB translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756713" ], "products": [ "species_10746731" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10737802": { "compartment": "compartment_70101", "id": "reaction_10737802", "reactome": "R-SPO-350598", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468" ], "products": [ "species_113528", "species_351164" ], "modifiers": [ [ "species_10737799", "catalyst" ] ], "additional_components": [ "SPAC144.04c" ] }, "reaction_10740399": { "compartment": "compartment_5460", "id": "reaction_10740399", "reactome": "R-SPO-916855", "name": "PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_916850" ], "products": [ "species_113552", "species_880046" ], "modifiers": [ [ "species_10740396", "catalyst" ] ], "additional_components": [ "CHEBI:33739", "O13837", "SPAC19D5.07" ] }, "reaction_10740363": { "compartment": "compartment_5460", "id": "reaction_10740363", "reactome": "R-SPO-888548", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_880046", "species_113526" ], "products": [ "species_113536", "species_29362", "species_113529" ], "modifiers": [ [ "species_10740360", "catalyst" ] ], "additional_components": [ "Q9US47", "SPAC1002.12c" ] }, "reaction_10735650": { "compartment": "compartment_7660", "id": "reaction_10735650", "reactome": "R-SPO-174451", "name": "Recruitment of DNA2 endonuclease to the C strand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735624", "species_10729513" ], "products": [ "species_10735626" ], "modifiers": [], "additional_components": [ "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "O14246", "SPAC6F6.16c", "Q96TL7", "SPBC1778.02", "P87324", "SPAC27E2.05", "CHEBI:15986", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "O13988", "SPAC26H5.06", "Q92372", "SPBC660.13c", "SPBC16D10.04c", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "O14246", "SPAC6F6.16c", "Q96TL7", "SPBC1778.02", "P87324", "SPAC27E2.05", "Q9URU2", "SPBC16D10.04c", "CHEBI:15986", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "O13988", "SPAC26H5.06", "Q92372", "SPBC660.13c" ] }, "reaction_10732942": { "compartment": "compartment_350", "id": "reaction_10732942", "reactome": "R-SPO-74986", "name": "Elongation of pre-rRNA transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_74985" ], "products": [ "species_74985" ], "modifiers": [ [ "species_10732500", "catalyst" ], [ "species_10732940", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "O94703", "SPCC1259.03", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O14086", "SPAC2F3.03c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "Q9UST5", "SPBC336.09c", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "Q9P7X8", "SPBP23A10.07", "O74366", "SPBC30B4.07c", "O43036", "SPBC3B9.07c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P40381", "SPAC664.01c", "P04909", "SPCC622.08c", "Q10103", "SPAC18G6.02c", "O42934", "SPBC16C6.10" ] }, "reaction_10732415": { "compartment": "compartment_7660", "id": "reaction_10732415", "reactome": "R-SPO-73757", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732406", "species_10732411" ], "products": [ "species_10732413" ], "modifiers": [], "additional_components": [ "O94703", "SPCC1259.03", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "O94616", "SPBC1289.07c", "O14086", "SPAC2F3.03c", "Q92399", "SPBC14C8.12", "Q9P7X8", "SPBP23A10.07", "O13877", "SPAC1B3.12c", "O43036", "SPBC3B9.07c", "SPAC18G6.11c", "O94703", "SPCC1259.03", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P15398", "SPBC4C3.05c", "Q10110", "SPAC18G6.11c", "P48011", "SPBC19C2.03", "O94616", "SPBC1289.07c", "O14086", "SPAC2F3.03c", "Q92399", "SPBC14C8.12", "Q9P7X8", "SPBP23A10.07", "O13877", "SPAC1B3.12c", "O43036", "SPBC3B9.07c" ] }, "reaction_10732502": { "compartment": "compartment_7660", "id": "reaction_10732502", "reactome": "R-SPO-73769", "name": "Loss of Rrn3 from RNA Polymerase I promoter escape complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732496" ], "products": [ "species_10732411", "species_10732500" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "O94703", "SPCC1259.03", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "Q10110", "SPAC18G6.11c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O14086", "SPAC2F3.03c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "Q9UST5", "SPBC336.09c", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "Q9P7X8", "SPBP23A10.07", "O74366", "SPBC30B4.07c", "O43036", "SPBC3B9.07c", "SPAC18G6.11c", "P36613", "SPBP16F5.02", "O94703", "SPCC1259.03", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O14086", "SPAC2F3.03c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "Q9UST5", "SPBC336.09c", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "Q9P7X8", "SPBP23A10.07", "O74366", "SPBC30B4.07c", "O43036", "SPBC3B9.07c" ] }, "reaction_10739704": { "compartment": "compartment_5460", "id": "reaction_10739704", "reactome": "R-SPO-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_159450" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10739701", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "P19117", "SPAC23C11.05" ] }, "reaction_10735146": { "compartment": "compartment_5460", "id": "reaction_10735146", "reactome": "R-SPO-164840", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_10735134", "species_113581" ], "products": [ "species_10735136" ], "modifiers": [], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "species_29370", "Q09774", "SPAC22F3.07c", "species_29372", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10735144": { "compartment": "compartment_5460", "id": "reaction_10735144", "reactome": "R-SPO-164834", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735138", "species_163953" ], "products": [ "species_10735134", "species_113529", "species_113593" ], "modifiers": [ [ "species_10735138", "catalyst" ] ], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "species_113592", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "species_113592", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10735141": { "compartment": "compartment_5460", "id": "reaction_10735141", "reactome": "R-SPO-164832", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735136" ], "products": [ "species_10735138", "species_113521" ], "modifiers": [ [ "species_10735136", "catalyst" ] ], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "species_29370", "Q09774", "SPAC22F3.07c", "species_29372", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "species_113592", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "species_29370", "Q09774", "SPAC22F3.07c", "species_29372", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10756939": { "compartment": "compartment_876", "id": "reaction_10756939", "reactome": "R-SPO-9018798", "name": "RHOV binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756937" ], "products": [ "species_10756922", "species_29420" ], "modifiers": [], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "Q01112", "SPAC110.03", "species_29438" ] }, "reaction_10756935": { "compartment": "compartment_876", "id": "reaction_10756935", "reactome": "R-SPO-9018794", "name": "RHOV binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756931", "species_10756922" ], "products": [ "species_10756933" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USZ0", "SPBC1306.02", "O43125", "SPBC119.05c", "Q10056", "SPAC1F5.09c", "Q9USR1", "SPBC577.08c", "Q01112", "SPAC110.03", "O13728", "SPAC15A10.08", "O14188", "SPAC4F8.13c", "O94466", "SPBC23G7.08c", "Q02088", "SPAC27F1.02c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10161", "SPAC26A3.05", "Q9USZ0", "SPBC1306.02", "O43125", "SPBC119.05c", "Q10056", "SPAC1F5.09c", "Q9USR1", "SPBC577.08c", "Q01112", "SPAC110.03", "O13728", "SPAC15A10.08", "O14188", "SPAC4F8.13c", "O94466", "SPBC23G7.08c", "Q02088", "SPAC27F1.02c", "species_29438", "P50527", "SPBC1604.14c" ] }, "reaction_10752666": { "compartment": "compartment_12045", "id": "reaction_10752666", "reactome": "R-SPO-6807053", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_6807054", "species_29368" ], "products": [ "species_29366", "species_6807057", "species_29356" ], "modifiers": [ [ "species_10736341", "catalyst" ] ], "additional_components": [ "O13666", "SPBC27B12.03c", "O94457", "SPAC1687.16c" ] }, "reaction_10743177": { "compartment": "compartment_1598585", "id": "reaction_10743177", "reactome": "R-SPO-2466068", "name": "Phosphorylation of cohesin by PLK1 at chromosomal arms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10743162" ], "products": [ "species_29370", "species_10743174" ], "modifiers": [ [ "species_10738046", "catalyst" ] ], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "O94383", "SPBC29A10.04", "P30776", "SPCC338.17c", "O94364", "SPBC428.17c", "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "Q9HFF5", "SPAC110.02", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c", "SPAC23C11.16" ] }, "reaction_10755724": { "compartment": "compartment_5460", "id": "reaction_10755724", "reactome": "R-SPO-8878815", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755715", "species_10755703" ], "products": [ "species_10755701", "species_10755717" ], "modifiers": [ [ "species_10755722", "catalyst" ] ], "additional_components": [ "P78859", "SPCC645.03c", "O43045", "SPBC3B9.17", "Q9HDW8", "SPAPB2B4.02", "CHEBI:33739", "SPAPB2B4.02", "CHEBI:49883", "P78859", "SPCC645.03c", "O43045", "SPBC3B9.17", "SPAC144.08" ] }, "reaction_10743108": { "compartment": "compartment_5460", "id": "reaction_10743108", "reactome": "R-SPO-2395517", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_113529", "species_10743106" ], "products": [ "species_113563", "species_10743104" ], "modifiers": [], "additional_components": [ "O59710", "SPBC3B8.01c", "species_113596", "O59710", "SPBC3B8.01c", "species_31649" ] }, "reaction_10741701": { "compartment": "compartment_5460", "id": "reaction_10741701", "reactome": "R-SPO-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741699", "species_113531" ], "products": [ "species_10741697" ], "modifiers": [], "additional_components": [ "Q9UTC6", "SPAC227.13c", "O74831", "SPCC1183.03c", "O60068", "SPBC13G1.06c", "O74351", "SPBC21D10.11c", "Q9UTC6", "SPAC227.13c", "O74831", "SPCC1183.03c", "O60068", "SPBC13G1.06c", "O74351", "SPBC21D10.11c", "species_113531" ] }, "reaction_10754910": { "compartment": "compartment_12045", "id": "reaction_10754910", "reactome": "R-SPO-8867876", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_392417" ], "products": [ "species_1806234", "species_33625" ], "modifiers": [ [ "species_10754907", "catalyst" ] ], "additional_components": [ "O74178", "SPBC1271.12", "O94512", "SPBC646.08c", "O43021", "SPBC354.07c", "Q9UUA1", "SPCC23B6.01c" ] }, "reaction_10742025": { "compartment": "compartment_12045", "id": "reaction_10742025", "reactome": "R-SPO-1482897", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498722", "species_1524021" ], "modifiers": [ [ "species_10741988", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741912": { "compartment": "compartment_12045", "id": "reaction_10741912", "reactome": "R-SPO-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498722", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741897": { "compartment": "compartment_12045", "id": "reaction_10741897", "reactome": "R-SPO-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498724", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741983": { "compartment": "compartment_12045", "id": "reaction_10741983", "reactome": "R-SPO-1482771", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498724", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10729620": { "compartment": "compartment_7660", "id": "reaction_10729620", "reactome": "R-SPO-69608", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10729577" ], "products": [ "species_113582", "species_10729589" ], "modifiers": [ [ "species_10729617", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC14C4.03" ] }, "reaction_10729587": { "compartment": "compartment_70101", "id": "reaction_10729587", "reactome": "R-SPO-69600", "name": "Proteolytic degradation of ubiquitinated-Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729585" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P06652", "SPAC24H6.05", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10729608": { "compartment": "compartment_7660", "id": "reaction_10729608", "reactome": "R-SPO-69604", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10729577" ], "products": [ "species_113582", "species_10729589" ], "modifiers": [ [ "species_10729605", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "O13945", "SPAC23H4.02", "O74536", "SPCC74.03c" ] }, "reaction_10742125": { "compartment": "compartment_70616", "id": "reaction_10742125", "reactome": "R-SPO-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110577", "species_1524101" ], "products": [ "species_1524064", "species_159450" ], "modifiers": [ [ "species_10742122", "catalyst" ] ], "additional_components": [ "SPBC13A2.03" ] }, "reaction_10743262": { "compartment": "compartment_7660", "id": "reaction_10743262", "reactome": "R-SPO-2468040", "name": "Cohesin binds PDS5 and WAPAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743242", "species_10743244", "species_10743248" ], "products": [ "species_10743250" ], "modifiers": [], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "SPAC110.02", "SPBC428.17c", "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c" ] }, "reaction_10734651": { "compartment": "compartment_7660", "id": "reaction_10734651", "reactome": "R-SPO-156723", "name": "Regulation of KIF20A (MKL2) by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10734646" ], "products": [ "species_113582", "species_10734649" ], "modifiers": [ [ "species_10734620", "catalyst" ] ], "additional_components": [ "SPBC15D4.01c", "SPBC15D4.01c", "SPAC23C11.16" ] }, "reaction_10743288": { "compartment": "compartment_1598585", "id": "reaction_10743288", "reactome": "R-SPO-2470935", "name": "Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2537690", "species_10743250", "species_10743280" ], "products": [ "species_10743286" ], "modifiers": [], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c", "O94459", "SPAC1687.18c", "Q09725", "SPAC31A2.05c", "Q92380", "SPCC4E9.01c", "O94459", "SPAC1687.18c", "O42649", "SPAC10F6.09c", "Q09725", "SPAC31A2.05c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c" ] }, "reaction_10734623": { "compartment": "compartment_7660", "id": "reaction_10734623", "reactome": "R-SPO-156673", "name": "Regulation of KIF23 (MKLP1) by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10734610" ], "products": [ "species_113582", "species_10734614" ], "modifiers": [ [ "species_10734620", "catalyst" ] ], "additional_components": [ "SPBC15D4.01c", "SPBC15D4.01c", "SPAC23C11.16" ] }, "reaction_10752664": { "compartment": "compartment_5460", "id": "reaction_10752664", "reactome": "R-SPO-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807477", "species_113593" ], "products": [ "species_113548", "species_113600", "species_113581", "species_113529" ], "modifiers": [ [ "species_10752661", "catalyst" ] ], "additional_components": [ "SPCC61.03" ] }, "reaction_10752656": { "compartment": "compartment_5460", "id": "reaction_10752656", "reactome": "R-SPO-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10752653", "catalyst" ] ], "additional_components": [ "O13725", "SPAC15A10.05c" ] }, "reaction_10753139": { "compartment": "compartment_17951", "id": "reaction_10753139", "reactome": "R-SPO-6809287", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389620", "species_141343", "species_192305" ], "products": [ "species_6809289", "species_193465" ], "modifiers": [ [ "species_10753136", "catalyst" ] ], "additional_components": [ "SPBC1778.03c" ] }, "reaction_10757787": { "compartment": "compartment_7660", "id": "reaction_10757787", "reactome": "R-SPO-9671145", "name": "DKC1 binds SHQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757783", "species_10734902" ], "products": [ "species_10757785" ], "modifiers": [], "additional_components": [ "SPBC8D2.13", "SPAC29A4.04c", "O43076", "SPBC8D2.13", "O14007", "SPAC29A4.04c" ] }, "reaction_10753499": { "compartment": "compartment_70101", "id": "reaction_10753499", "reactome": "R-SPO-6814119", "name": "TRiC/CCT binds unfolded G-protein beta subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738448", "species_10753491" ], "products": [ "species_10753497" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "SPBC32H8.07", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10753507": { "compartment": "compartment_70101", "id": "reaction_10753507", "reactome": "R-SPO-6814124", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753497" ], "products": [ "species_29370", "species_10753503" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_113592", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10738452": { "compartment": "compartment_70101", "id": "reaction_10738452", "reactome": "R-SPO-391266", "name": "Association of CCT/TriC with sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738448", "species_10738404" ], "products": [ "species_10738450" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "SPAC4A8.07c", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "O14159", "SPAC4A8.07c", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10753505": { "compartment": "compartment_70101", "id": "reaction_10753505", "reactome": "R-SPO-6814120", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753503" ], "products": [ "species_29372", "species_10753497" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_113592", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10752940": { "compartment": "compartment_6791047", "id": "reaction_10752940", "reactome": "R-SPO-6807877", "name": "ARFGAPs stimulate ARF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752857" ], "products": [ "species_10752937", "species_10752792", "species_10746137", "species_10752725" ], "modifiers": [ [ "species_10752857", "catalyst" ] ], "additional_components": [ "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "O13728", "SPAC15A10.08", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O60073", "SPBC13G1.11", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "O13932", "SPAC23C4.13", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "Q09857", "SPAC29E6.03c", "O13946", "SPAC23H4.03c", "O13728", "SPAC15A10.08", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "O42937", "SPBC16C6.13c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "O60073", "SPBC13G1.11", "Q9P7I9", "SPCC24B10.17", "O13932", "SPAC23C4.13", "P11620", "SPBC1703.10", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "Q09857", "SPAC29E6.03c", "SPAC22E12.17c", "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "O13728", "SPAC15A10.08", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O60073", "SPBC13G1.11", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "O13932", "SPAC23C4.13", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "Q09857", "SPAC29E6.03c" ] }, "reaction_10753303": { "compartment": "compartment_12045", "id": "reaction_10753303", "reactome": "R-SPO-6811425", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753301", "species_10739129", "species_10749814" ], "products": [ "species_10753292" ], "modifiers": [], "additional_components": [ "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "O13785", "SPAC17G6.07c", "O42852", "SPAC23A1.15c", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "Q9P4X4", "SPAC959.02", "O13785", "SPAC17G6.07c", "Q9P7Q4", "SPAC1834.11c", "O42852", "SPAC23A1.15c" ] }, "reaction_10749851": { "compartment": "compartment_6791047", "id": "reaction_10749851", "reactome": "R-SPO-5694423", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10749847", "species_10749814" ], "products": [ "species_10749849" ], "modifiers": [], "additional_components": [ "SPAC959.02", "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P7Q4", "SPAC1834.11c", "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10754292": { "compartment": "compartment_17938", "id": "reaction_10754292", "reactome": "R-SPO-8854255", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754282", "species_29356" ], "products": [ "species_29372", "species_10754284" ], "modifiers": [ [ "species_10754282", "catalyst" ], [ "species_10754290", "catalyst" ] ], "additional_components": [ "O94655", "SPBC405.04c", "CHEBI:15996", "species_29420", "O94655", "SPBC405.04c", "O94655", "SPBC405.04c", "CHEBI:15996", "SPAC4G8.04" ] }, "reaction_10740660": { "compartment": "compartment_70101", "id": "reaction_10740660", "reactome": "R-SPO-917700", "name": "MVB Vesicle Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740430", "species_10740658" ], "products": [ "species_10740526", "species_10740656" ], "modifiers": [], "additional_components": [ "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "P0CH07", "SPAC1805.12c", "O74967", "SPBC4B4.06", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O43038", "SPBC3B9.09", "species_179838", "O94663", "SPBC651.05c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "P0C8R3", "SPAC589.10c", "O14296", "SPAC9E9.14", "species_179838", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "P0CH06", "SPAC11G7.04", "O74967", "SPBC4B4.06", "O43038", "SPBC3B9.09", "O94663", "SPBC651.05c" ] }, "reaction_10753584": { "compartment": "compartment_6791047", "id": "reaction_10753584", "reactome": "R-SPO-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753579" ], "products": [ "species_10749719", "species_10753577" ], "modifiers": [ [ "species_10753579", "catalyst" ] ], "additional_components": [ "P11620", "SPBC1703.10", "species_29438", "O94661", "SPBC651.03c", "species_29420", "P11620", "SPBC1703.10", "SPBC651.03c", "P11620", "SPBC1703.10", "species_29438", "O94661", "SPBC651.03c" ] }, "reaction_10754588": { "compartment": "compartment_876", "id": "reaction_10754588", "reactome": "R-SPO-8862280", "name": "FCHo proteins bind nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754497", "species_10754509", "species_10754481", "species_10754426", "species_10754471", "species_10754491" ], "products": [ "species_10754511" ], "modifiers": [], "additional_components": [ "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "species_179856", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "Q9USZ7", "SPBC11G11.02c", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "O94685", "SPBC83.01", "Q9USZ7", "SPBC11G11.02c", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "O94685", "SPBC83.01", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "Q9USZ7", "SPBC11G11.02c", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "O94685", "SPBC83.01", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q9Y7L6", "SPBC685.04c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_179856", "O94685", "SPBC83.01" ] }, "reaction_10755426": { "compartment": "compartment_876", "id": "reaction_10755426", "reactome": "R-SPO-8871196", "name": "Initial binding of AP-2 and clathrin to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754388", "species_10738801", "species_179856" ], "products": [ "species_10754497" ], "modifiers": [], "additional_components": [ "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "species_179856" ] }, "reaction_10753408": { "compartment": "compartment_263163", "id": "reaction_10753408", "reactome": "R-SPO-6811428", "name": "RIC1:RGP1 recruits RAB6:GDP to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753400", "species_10753388" ], "products": [ "species_10753406" ], "modifiers": [], "additional_components": [ "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "species_29420", "P17608", "SPAC4C5.02c", "species_29420", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c" ] }, "reaction_10753602": { "compartment": "compartment_263163", "id": "reaction_10753602", "reactome": "R-SPO-8847534", "name": "RAB43 hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753595" ], "products": [ "species_10753599" ], "modifiers": [ [ "species_10753595", "catalyst" ] ], "additional_components": [ "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "species_29438", "species_29420", "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "species_29438" ] }, "reaction_10755664": { "compartment": "compartment_13946", "id": "reaction_10755664", "reactome": "R-SPO-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755636" ], "products": [ "species_10755437", "species_10755646", "species_29420" ], "modifiers": [ [ "species_10755661", "catalyst" ] ], "additional_components": [ "species_29420", "P11620", "SPBC1703.10", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P11620", "SPBC1703.10", "species_29438", "O74748", "SPBC1734.07c", "O14251", "SPAC6G10.05c", "Q9UT70", "SPAC3G9.16c", "Q9USZ5", "SPBC11G11.04", "Q9P6P5", "SPAC644.18c", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O13732", "SPAC15A10.12c", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12" ] }, "reaction_10753415": { "compartment": "compartment_263163", "id": "reaction_10753415", "reactome": "R-SPO-6811429", "name": "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10753406" ], "products": [ "species_29420", "species_10753412" ], "modifiers": [ [ "species_10753406", "catalyst" ] ], "additional_components": [ "species_29420", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c", "species_29438", "species_29420", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c" ] }, "reaction_10755452": { "compartment": "compartment_216813", "id": "reaction_10755452", "reactome": "R-SPO-8875318", "name": "RAB3 GEFs exchange GTP for GDP on RAB3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755439" ], "products": [ "species_10755437", "species_10755447", "species_29420" ], "modifiers": [ [ "species_10755449", "catalyst" ] ], "additional_components": [ "species_29420", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17609", "SPAC9E9.07c", "species_29438", "O13876", "SPAC1B3.11c", "SPAC23C4.10" ] }, "reaction_10755040": { "compartment": "compartment_876", "id": "reaction_10755040", "reactome": "R-SPO-8868651", "name": "Endophilins recruit synaptojanins to the clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755020", "species_10742387" ], "products": [ "species_10755033" ], "modifiers": [], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856", "SPBC2G2.02", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10753710": { "compartment": "compartment_20699", "id": "reaction_10753710", "reactome": "R-SPO-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753701" ], "products": [ "species_10753707" ], "modifiers": [ [ "species_10753701", "catalyst" ] ], "additional_components": [ "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753246": { "compartment": "compartment_20699", "id": "reaction_10753246", "reactome": "R-SPO-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10753235" ], "products": [ "species_10753239", "species_29420" ], "modifiers": [ [ "species_10753235", "catalyst" ] ], "additional_components": [ "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10754846": { "compartment": "compartment_876", "id": "reaction_10754846", "reactome": "R-SPO-8867613", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738025", "species_10754842" ], "products": [ "species_10754844" ], "modifiers": [], "additional_components": [ "SPAC6G9.11", "O60167", "SPBC19F8.03c", "Q92356", "SPAC6G9.11", "O60167", "SPBC19F8.03c" ] }, "reaction_10753617": { "compartment": "compartment_20699", "id": "reaction_10753617", "reactome": "R-SPO-8847638", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753612" ], "products": [ "species_29370", "species_10753102", "species_10739129", "species_10753091", "species_10749814", "species_10753100", "species_10753002" ], "modifiers": [ [ "species_10753612", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "SPBC8D2.14c", "SPAC959.02", "SPAC4G8.10", "Q9P7Q4", "SPAC1834.11c", "Q09730", "SPAC31A2.13c", "O13932", "SPAC23C4.13", "SPBC13G1.11", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10737431": { "compartment": "compartment_70101", "id": "reaction_10737431", "reactome": "R-SPO-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10737423" ], "products": [ "species_10737349", "species_29420" ], "modifiers": [ [ "species_10737428", "catalyst" ] ], "additional_components": [ "species_29420", "Q01475", "SPBC31F10.06c", "Q01475", "SPBC31F10.06c", "species_29438", "SPBC3H7.01" ] }, "reaction_10749854": { "compartment": "compartment_6791047", "id": "reaction_10749854", "reactome": "R-SPO-5694425", "name": "NSF ATPase activity dissociates cis-SNARE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10749849" ], "products": [ "species_10749821", "species_10749837", "species_10739129", "species_10749828", "species_10749814", "species_10749845", "species_29372", "species_10749823" ], "modifiers": [ [ "species_10749849", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "SPAC23C4.13", "O13644", "SPBC8D2.14c", "O94651", "SPBC31E1.04", "SPAC959.02", "SPCC74.01", "Q9P7Q4", "SPAC1834.11c", "O60073", "SPBC13G1.11", "Q9Y7L0", "SPBC2A9.08c", "SPAP14E8.03", "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10753581": { "compartment": "compartment_6791047", "id": "reaction_10753581", "reactome": "R-SPO-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753577", "species_10749883" ], "products": [ "species_10753579" ], "modifiers": [], "additional_components": [ "SPBC651.03c", "P11620", "SPBC1703.10", "species_29438", "P11620", "SPBC1703.10", "species_29438", "O94661", "SPBC651.03c" ] }, "reaction_10754326": { "compartment": "compartment_17938", "id": "reaction_10754326", "reactome": "R-SPO-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10754316" ], "products": [ "species_10754318", "species_29372" ], "modifiers": [ [ "species_10754316", "catalyst" ], [ "species_10754324", "catalyst" ] ], "additional_components": [ "O94655", "SPBC405.04c", "Q9HDY0", "SPAPB1A10.10c", "CHEBI:15996", "O94655", "SPBC405.04c", "Q9HDY0", "SPAPB1A10.10c", "species_111349", "O94655", "SPBC405.04c", "Q9HDY0", "SPAPB1A10.10c", "CHEBI:15996", "SPAC630.05" ] }, "reaction_10753567": { "compartment": "compartment_263163", "id": "reaction_10753567", "reactome": "R-SPO-6814684", "name": "cis-SNARE binds SNAPs and NSF hexamer at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10753563", "species_10749814" ], "products": [ "species_10753565" ], "modifiers": [], "additional_components": [ "SPAC959.02", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q9P6P1", "SPAC823.05c", "Q9P7Q4", "SPAC1834.11c", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c" ] }, "reaction_10752744": { "compartment": "compartment_6791047", "id": "reaction_10752744", "reactome": "R-SPO-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10752737" ], "products": [ "species_29370", "species_10752741" ], "modifiers": [ [ "species_10752737", "catalyst" ] ], "additional_components": [ "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10754916": { "compartment": "compartment_876", "id": "reaction_10754916", "reactome": "R-SPO-8868072", "name": "Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10754884", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9USP6", "SPBC9B6.08", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10757826": { "compartment": "compartment_70101", "id": "reaction_10757826", "reactome": "R-SPO-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754388", "species_9648300" ], "products": [ "species_10754724" ], "modifiers": [], "additional_components": [ "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_9648300", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10754525": { "compartment": "compartment_876", "id": "reaction_10754525", "reactome": "R-SPO-8856813", "name": "AAK1 phosphorylates AP-2 mu subunit at T156", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10754515" ], "products": [ "species_29370", "species_10754522" ], "modifiers": [ [ "species_10754515", "catalyst" ] ], "additional_components": [ "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_179856", "O94685", "SPBC83.01", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O94685", "SPBC83.01", "species_179856", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_179856", "O94685", "SPBC83.01", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02" ] }, "reaction_10755038": { "compartment": "compartment_876", "id": "reaction_10755038", "reactome": "R-SPO-8868648", "name": "SYNJ hydrolyze PI(4,5)P2 to PI(4)P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755033", "species_29356" ], "products": [ "species_29372", "species_10755035" ], "modifiers": [ [ "species_10755033", "catalyst" ] ], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "species_1806234", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "species_29438", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10749891": { "compartment": "compartment_6791047", "id": "reaction_10749891", "reactome": "R-SPO-5694441", "name": "CSNK1D phosphorylates SEC23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10749871" ], "products": [ "species_29370", "species_10749807", "species_10737297", "species_10749877", "species_10749883", "species_10749768", "species_10749875" ], "modifiers": [ [ "species_10749888", "catalyst" ] ], "additional_components": [ "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q10149", "SPAC1D4.02c", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15", "Q09857", "SPAC29E6.03c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13637", "SPBC8D2.20c", "O94319", "SPBC215.15", "P87109", "SPAC20G8.02", "O13644", "SPBC8D2.14c", "O60073", "SPBC13G1.11", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q10149", "SPAC1D4.02c", "Q9Y7L0", "SPBC2A9.08c", "Q9USS7", "SPBC4.03c", "Q09857", "SPAC29E6.03c", "P11620", "SPBC1703.10", "species_29438", "O14251", "SPAC6G10.05c", "Q9UT70", "SPAC3G9.16c", "Q9USZ5", "SPBC11G11.04", "Q9P6P5", "SPAC644.18c", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O13732", "SPAC15A10.12c", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "SPCC31H12.07", "SPBC3H7.15" ] }, "reaction_10737888": { "compartment": "compartment_70101", "id": "reaction_10737888", "reactome": "R-SPO-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10737859" ], "products": [ "species_10737863", "species_29420" ], "modifiers": [ [ "species_10737885", "catalyst" ] ], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "P36579", "SPBC4F6.18c", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753554": { "compartment": "compartment_263163", "id": "reaction_10753554", "reactome": "R-SPO-6814676", "name": "SNAPs and NSF hexamer bind cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10753550", "species_10749814" ], "products": [ "species_10753552" ], "modifiers": [], "additional_components": [ "SPAC959.02", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P6P1", "SPAC823.05c", "Q9P7Q4", "SPAC1834.11c", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c" ] }, "reaction_10753606": { "compartment": "compartment_263163", "id": "reaction_10753606", "reactome": "R-SPO-8847537", "name": "RAB43:GTP binds USP8NL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753593", "species_10753604" ], "products": [ "species_10753595" ], "modifiers": [], "additional_components": [ "P11620", "SPBC1703.10", "species_29438", "SPAC26F1.09", "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "species_29438" ] }, "reaction_10755079": { "compartment": "compartment_24339", "id": "reaction_10755079", "reactome": "R-SPO-8868658", "name": "HSPA8-mediated ATP hydrolysis promotes vesicle uncoating", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755070", "species_29356" ], "products": [ "species_10755072", "species_10755076", "species_29372" ], "modifiers": [ [ "species_10755070", "catalyst" ] ], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q10265", "SPAC13G7.02c", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "species_29370", "Q10265", "SPAC13G7.02c", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q10265", "SPAC13G7.02c", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10749918": { "compartment": "compartment_70101", "id": "reaction_10749918", "reactome": "R-SPO-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737373" ], "products": [ "species_10737439", "species_29372", "species_10737371", "species_10737423" ], "modifiers": [ [ "species_10737373", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9USS7", "SPBC4.03c", "species_29420", "Q01475", "SPBC31F10.06c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438" ] }, "reaction_10753635": { "compartment": "compartment_20699", "id": "reaction_10753635", "reactome": "R-SPO-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742399", "species_10753631" ], "products": [ "species_10753633" ], "modifiers": [], "additional_components": [ "P36579", "SPBC4F6.18c", "CHEBI:15996", "O42903", "SPBC119.12", "O60109", "SPBC14F5.13c", "O42903", "SPBC119.12", "P36579", "SPBC4F6.18c", "O60109", "SPBC14F5.13c", "CHEBI:15996" ] }, "reaction_10752733": { "compartment": "compartment_6791047", "id": "reaction_10752733", "reactome": "R-SPO-6807864", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752729", "species_10749883", "species_10752725" ], "products": [ "species_10752731" ], "modifiers": [], "additional_components": [ "Q09857", "SPAC29E6.03c", "P11620", "SPBC1703.10", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753120": { "compartment": "compartment_20699", "id": "reaction_10753120", "reactome": "R-SPO-6809014", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10749814", "species_10753116" ], "products": [ "species_10753118" ], "modifiers": [], "additional_components": [ "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10753237": { "compartment": "compartment_20699", "id": "reaction_10753237", "reactome": "R-SPO-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746137", "species_10753233" ], "products": [ "species_10753235" ], "modifiers": [], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753123": { "compartment": "compartment_20699", "id": "reaction_10753123", "reactome": "R-SPO-6809015", "name": "NSF ATPase activity dissociates cis-SNARE at cis-Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753118", "species_113592" ], "products": [ "species_10753102", "species_10753106", "species_10753091", "species_29372", "species_10753100", "species_10753074", "species_10753002" ], "modifiers": [ [ "species_10753118", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "SPBC8D2.14c", "SPAP14E8.03", "SPAC4G8.10", "Q09730", "SPAC31A2.13c", "O13932", "SPAC23C4.13", "SPAC23C4.13", "SPBC13G1.11", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10753260": { "compartment": "compartment_20699", "id": "reaction_10753260", "reactome": "R-SPO-6811417", "name": "ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752792", "species_10753256", "species_10753241", "species_10753250", "species_10753070" ], "products": [ "species_10753258" ], "modifiers": [], "additional_components": [ "SPAC22E12.17c", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P36579", "SPBC4F6.18c", "P87140", "SPAC57A7.10c", "P11620", "SPBC1703.10", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "SPBC2A9.08c", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06" ] }, "reaction_10737445": { "compartment": "compartment_12045", "id": "reaction_10737445", "reactome": "R-SPO-204008", "name": "SEC31:SEC13 and v-SNARE recruitment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737297", "species_10737379", "species_10737310" ], "products": [ "species_10737381" ], "modifiers": [], "additional_components": [ "O13637", "SPBC8D2.20c", "O94319", "SPBC215.15", "P87109", "SPAC20G8.02", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "O14029", "SPAC29B12.07", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O60073", "SPBC13G1.11", "Q9Y7L0", "SPBC2A9.08c", "O13637", "SPBC8D2.20c", "O14029", "SPAC29B12.07", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "P87109", "SPAC20G8.02", "O13644", "SPBC8D2.14c", "O60073", "SPBC13G1.11", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O94319", "SPBC215.15" ] }, "reaction_10754333": { "compartment": "compartment_5683628", "id": "reaction_10754333", "reactome": "R-SPO-8854588", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747277", "species_10754329" ], "products": [ "species_10754331" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "SPAC630.05", "O94272", "SPBP8B7.24c", "Q9UUH7", "SPAC630.05" ] }, "reaction_10754886": { "compartment": "compartment_876", "id": "reaction_10754886", "reactome": "R-SPO-8867756", "name": "CLASP proteins and cargo are recruited to the nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754878", "species_10754522" ], "products": [ "species_10754880" ], "modifiers": [], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9P7V2", "SPAC30.04c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O94685", "SPBC83.01", "species_179856", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9USP6", "SPBC9B6.08", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10755085": { "compartment": "compartment_24339", "id": "reaction_10755085", "reactome": "R-SPO-8868659", "name": "Clathrin recruits auxilins to the clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755081", "species_10739268" ], "products": [ "species_10755083" ], "modifiers": [], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "SPAC17A5.12", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10749791": { "compartment": "compartment_12045", "id": "reaction_10749791", "reactome": "R-SPO-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737367", "species_10737361", "species_10737369" ], "products": [ "species_10737371" ], "modifiers": [], "additional_components": [ "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "Q9P7G5", "SPAP14E8.03", "SPCC31H12.07", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9USS7", "SPBC4.03c" ] }, "reaction_10754599": { "compartment": "compartment_70101", "id": "reaction_10754599", "reactome": "R-SPO-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754595", "species_10749451" ], "products": [ "species_10754591" ], "modifiers": [], "additional_components": [ "SPAC31A2.09c", "SPBC12D12.08c", "SPAC31A2.09c" ] }, "reaction_10753248": { "compartment": "compartment_20699", "id": "reaction_10753248", "reactome": "R-SPO-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753032", "species_10752725" ], "products": [ "species_10753233" ], "modifiers": [], "additional_components": [ "P11620", "SPBC1703.10", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10738021": { "compartment": "compartment_70101", "id": "reaction_10738021", "reactome": "R-SPO-376364", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738012", "species_10738014", "species_10738010" ], "products": [ "species_10738012", "species_10738016", "species_10738010" ], "modifiers": [ [ "species_10738018", "catalyst" ] ], "additional_components": [ "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "Q92356", "SPAC6G9.11", "O74786", "SPBC26H8.02c", "Q9USH7", "SPCC825.03c" ] }, "reaction_10753384": { "compartment": "compartment_12045", "id": "reaction_10753384", "reactome": "R-SPO-6811427", "name": "COPI vesicle uncoating at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753382" ], "products": [ "species_10753301", "species_10749719", "species_10753380", "species_10752783", "species_10753346" ], "modifiers": [], "additional_components": [ "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "O42852", "SPAC23A1.15c", "O42937", "SPBC16C6.13c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "P11620", "SPBC1703.10", "Q9C0W8", "SPBC691.02c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O13785", "SPAC17G6.07c", "O74559", "SPCC970.06", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "O13785", "SPAC17G6.07c", "O42852", "SPAC23A1.15c", "species_29420", "P11620", "SPBC1703.10", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "O42937", "SPBC16C6.13c", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c" ] }, "reaction_10755090": { "compartment": "compartment_876", "id": "reaction_10755090", "reactome": "R-SPO-8868661", "name": "Dynamin-mediated GTP hydrolysis promotes vesicle scission", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10755035" ], "products": [ "species_10755081", "species_29372" ], "modifiers": [ [ "species_10755035", "catalyst" ] ], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "species_1806234", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "species_29438", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "species_1806234", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "species_29438", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10753713": { "compartment": "compartment_20699", "id": "reaction_10753713", "reactome": "R-SPO-8848484", "name": "PLA2s hydrolyze phospholipids at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_29356" ], "products": [ "species_6814303", "species_8848483" ], "modifiers": [ [ "species_10739104", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10740639": { "compartment": "compartment_74700", "id": "reaction_10740639", "reactome": "R-SPO-917693", "name": "ESCRT Disassembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740526", "species_113592" ], "products": [ "species_10740409", "species_29370", "species_10740404", "species_10740428", "species_10740414", "species_10740423", "species_29372", "species_10740620" ], "modifiers": [ [ "species_10740636", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "P0C8R3", "SPAC589.10c", "O14296", "SPAC9E9.14", "species_179838", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "P0CH06", "SPAC11G7.04", "SPAC9E9.14", "SPAC4F8.01", "SPCC162.06c", "SPAC1142.07c", "SPBC215.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "species_179838", "P0CH06", "SPAC11G7.04", "O74422", "SPCC162.06c", "Q09803", "SPAC2G11.06", "O13703", "SPAC13F5.04c" ] }, "reaction_10753614": { "compartment": "compartment_20699", "id": "reaction_10753614", "reactome": "R-SPO-8847637", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10749814", "species_10753610" ], "products": [ "species_10753612" ], "modifiers": [], "additional_components": [ "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10749856": { "compartment": "compartment_13959", "id": "reaction_10749856", "reactome": "R-SPO-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749719", "species_10749768", "species_10737419" ], "products": [ "species_10749770" ], "modifiers": [], "additional_components": [ "species_29420", "P11620", "SPBC1703.10", "O14251", "SPAC6G10.05c", "Q9UT70", "SPAC3G9.16c", "Q9USZ5", "SPBC11G11.04", "Q9P6P5", "SPAC644.18c", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O13732", "SPAC15A10.12c", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "O60073", "SPBC13G1.11", "O13637", "SPBC8D2.20c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O94319", "SPBC215.15", "P87109", "SPAC20G8.02", "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "species_29420", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "Q09784", "SPAC13G6.05c", "P11620", "SPBC1703.10", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15" ] }, "reaction_10753557": { "compartment": "compartment_263163", "id": "reaction_10753557", "reactome": "R-SPO-6814678", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753552", "species_113592" ], "products": [ "species_10753539", "species_29370", "species_10739129", "species_10753544", "species_10753548", "species_10753546", "species_10749814" ], "modifiers": [ [ "species_10753552", "catalyst" ] ], "additional_components": [ "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c", "SPBC36B7.07", "SPAC959.02", "SPAC823.05c", "SPAC6G9.11", "SPBC3B9.10", "Q9P7Q4", "SPAC1834.11c", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c" ] }, "reaction_10753703": { "compartment": "compartment_20699", "id": "reaction_10753703", "reactome": "R-SPO-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742399", "species_10753667" ], "products": [ "species_10753701" ], "modifiers": [], "additional_components": [ "P36579", "SPBC4F6.18c", "CHEBI:15996", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10749795": { "compartment": "compartment_12045", "id": "reaction_10749795", "reactome": "R-SPO-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737433", "species_10737302", "species_10737369" ], "products": [ "species_10749793" ], "modifiers": [], "additional_components": [ "SPAC22F8.08", "SPBC2A9.08c", "SPCC31H12.07", "O74873", "SPCC31H12.07", "Q9Y7L0", "SPBC2A9.08c", "Q9UUI5", "SPAC22F8.08" ] }, "reaction_10752739": { "compartment": "compartment_6791047", "id": "reaction_10752739", "reactome": "R-SPO-6807866", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746137", "species_10752731" ], "products": [ "species_10752737" ], "modifiers": [], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10754348": { "compartment": "compartment_262783", "id": "reaction_10754348", "reactome": "R-SPO-8854759", "name": "TBC1D14 binds RAB11 and ULK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754344", "species_10754335", "species_10754339" ], "products": [ "species_10754346" ], "modifiers": [], "additional_components": [ "SPAC23D3.03c", "SPAC18G6.03", "SPCC63.08c", "P17610", "SPAC18G6.03", "Q9Y7T4", "SPCC63.08c", "Q09844", "SPAC23D3.03c" ] }, "reaction_10749777": { "compartment": "compartment_13959", "id": "reaction_10749777", "reactome": "R-SPO-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10749770" ], "products": [ "species_10749774", "species_29420" ], "modifiers": [ [ "species_10749770", "catalyst" ] ], "additional_components": [ "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "species_29420", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "Q09784", "SPAC13G6.05c", "P11620", "SPBC1703.10", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15", "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15", "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "species_29420", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "Q09784", "SPAC13G6.05c", "P11620", "SPBC1703.10", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15" ] }, "reaction_10754306": { "compartment": "compartment_262783", "id": "reaction_10754306", "reactome": "R-SPO-8854293", "name": "TBC1D10A (EPI64) binds ARF6:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754295", "species_10754302" ], "products": [ "species_10754304" ], "modifiers": [], "additional_components": [ "SPBC1778.09", "Q9Y7Z2", "SPBC1539.08", "species_29438", "Q9Y7J5", "SPBC1778.09", "Q9Y7Z2", "SPBC1539.08", "species_29438" ] }, "reaction_10755558": { "compartment": "compartment_263163", "id": "reaction_10755558", "reactome": "R-SPO-8876193", "name": "RIC1-RGP1 exchanges GTP for GDP on RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755545" ], "products": [ "species_10755437", "species_10755549", "species_29420" ], "modifiers": [ [ "species_10755555", "catalyst" ] ], "additional_components": [ "species_29420", "P17608", "SPAC4C5.02c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17608", "SPAC4C5.02c", "species_29438", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c" ] }, "reaction_10745653": { "compartment": "compartment_263163", "id": "reaction_10745653", "reactome": "R-SPO-5333658", "name": "CLAT:AP1:CLVS bind PI(3,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745649", "species_5334668" ], "products": [ "species_10745651" ], "modifiers": [], "additional_components": [ "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UU81", "SPCP1E11.06", "Q9HFE5", "SPBP16F5.07", "O43079", "SPBC947.02", "Q9P7N2", "SPAP27G11.06c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "species_6809774", "Q9UU81", "SPCP1E11.06", "Q9HFE5", "SPBP16F5.07", "O43079", "SPBC947.02", "Q9P7N2", "SPAP27G11.06c" ] }, "reaction_10753295": { "compartment": "compartment_12045", "id": "reaction_10753295", "reactome": "R-SPO-6811422", "name": "NSF ATPase activity dissociates cis-SNARE at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753292" ], "products": [ "species_10753288", "species_10753278", "species_10739129", "species_10753283", "species_10737302", "species_10749814", "species_29372" ], "modifiers": [ [ "species_10753292", "catalyst" ] ], "additional_components": [ "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "Q9P4X4", "SPAC959.02", "O13785", "SPAC17G6.07c", "Q9P7Q4", "SPAC1834.11c", "O42852", "SPAC23A1.15c", "SPAC17G6.07c", "SPAC23A1.15c", "SPAC959.02", "SPCC895.04c", "SPBC2A9.08c", "Q9P7Q4", "SPAC1834.11c", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "Q9P4X4", "SPAC959.02", "O13785", "SPAC17G6.07c", "Q9P7Q4", "SPAC1834.11c", "O42852", "SPAC23A1.15c" ] }, "reaction_10755022": { "compartment": "compartment_876", "id": "reaction_10755022", "reactome": "R-SPO-8868236", "name": "BAR domain proteins recruit dynamin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755018", "species_10755016" ], "products": [ "species_10755020" ], "modifiers": [], "additional_components": [ "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "species_29438", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q9P6L5", "SPAC688.11", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10738030": { "compartment": "compartment_876", "id": "reaction_10738030", "reactome": "R-SPO-376369", "name": "Vamp2 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738012", "species_10738023", "species_10738010" ], "products": [ "species_10738012", "species_10738025", "species_10738010" ], "modifiers": [ [ "species_10738027", "catalyst" ] ], "additional_components": [ "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "Q92356", "SPAC6G9.11", "O74786", "SPBC26H8.02c", "Q9USH7", "SPCC825.03c" ] }, "reaction_10754913": { "compartment": "compartment_876", "id": "reaction_10754913", "reactome": "R-SPO-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10742317", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10753273": { "compartment": "compartment_20699", "id": "reaction_10753273", "reactome": "R-SPO-6811418", "name": "ARFGAPs stimulate ARF GTPase activity at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753258" ], "products": [ "species_10752792", "species_10746137", "species_10752725", "species_10753270" ], "modifiers": [ [ "species_10753258", "catalyst" ] ], "additional_components": [ "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "SPAC22E12.17c", "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "O42937", "SPBC16C6.13c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06" ] }, "reaction_10755570": { "compartment": "compartment_70101", "id": "reaction_10755570", "reactome": "R-SPO-8876446", "name": "p-ULK1 phosphorylates DENND3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755563", "species_113592" ], "products": [ "species_29370", "species_10755567" ], "modifiers": [ [ "species_10746793", "catalyst" ] ], "additional_components": [ "SPCC297.05", "SPCC297.05", "SPCC63.08c" ] }, "reaction_10753243": { "compartment": "compartment_20699", "id": "reaction_10753243", "reactome": "R-SPO-6811412", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752783", "species_10753239" ], "products": [ "species_10753241" ], "modifiers": [], "additional_components": [ "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "O42937", "SPBC16C6.13c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P36579", "SPBC4F6.18c", "P87140", "SPAC57A7.10c", "P11620", "SPBC1703.10", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10755087": { "compartment": "compartment_24339", "id": "reaction_10755087", "reactome": "R-SPO-8868660", "name": "Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755083", "species_10755046" ], "products": [ "species_10755070" ], "modifiers": [], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_113592", "Q10265", "SPAC13G7.02c", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q10265", "SPAC13G7.02c", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10754726": { "compartment": "compartment_876", "id": "reaction_10754726", "reactome": "R-SPO-8866277", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754388", "species_10754720" ], "products": [ "species_10754722" ], "modifiers": [ [ "species_10754724", "inhibitor" ] ], "additional_components": [ "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q92337", "SPAC9E9.12c", "O74852", "SPCC18.02", "Q9P7V2", "SPAC30.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9P7V2", "SPAC30.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_9648300", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10749915": { "compartment": "compartment_12045", "id": "reaction_10749915", "reactome": "R-SPO-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737349", "species_10737439", "species_10737371" ], "products": [ "species_10737373" ], "modifiers": [], "additional_components": [ "Q01475", "SPBC31F10.06c", "species_29438", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438" ] }, "reaction_10755587": { "compartment": "compartment_262783", "id": "reaction_10755587", "reactome": "R-SPO-8876454", "name": "DENND3 exchanges GTP for GDP on RAB12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755574" ], "products": [ "species_10755437", "species_10755582", "species_29420" ], "modifiers": [ [ "species_10755584", "catalyst" ] ], "additional_components": [ "species_29420", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "species_29438", "Q9Y7Q7", "SPCC297.05" ] }, "reaction_10755519": { "compartment": "compartment_263163", "id": "reaction_10755519", "reactome": "R-SPO-8876190", "name": "RAB8 GEFs exchange GTP for GDP on RAB8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755502" ], "products": [ "species_10755437", "species_10755514", "species_29420" ], "modifiers": [ [ "species_10755516", "catalyst" ] ], "additional_components": [ "species_29420", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "species_29438", "O13930", "SPAC23C4.10", "C6Y4C9", "SPCC1183.12" ] }, "reaction_10752787": { "compartment": "compartment_6791047", "id": "reaction_10752787", "reactome": "R-SPO-6807872", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752741", "species_10752783" ], "products": [ "species_10752785" ], "modifiers": [], "additional_components": [ "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "O42937", "SPBC16C6.13c", "O13690", "SPBC211.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "Q09857", "SPAC29E6.03c" ] }, "reaction_10754708": { "compartment": "compartment_70101", "id": "reaction_10754708", "reactome": "R-SPO-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754684", "species_10754704" ], "products": [ "species_10754706" ], "modifiers": [], "additional_components": [ "Q10169", "SPBC3B8.05", "O42967", "SPBC1E8.02", "Q9USZ7", "SPBC11G11.02c", "O74423", "SPCC162.07", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "P78813", "SPCC794.11c", "O94685", "SPBC83.01", "Q9USZ7", "SPBC11G11.02c", "Q10169", "SPBC3B8.05", "O74423", "SPCC162.07", "Q9HGL2", "SPBC800.10c", "O42967", "SPBC1E8.02", "Q10172", "SPAC25G10.09c", "P78813", "SPCC794.11c", "O94685", "SPBC83.01" ] }, "reaction_10735482": { "compartment": "compartment_7660", "id": "reaction_10735482", "reactome": "R-SPO-174110", "name": "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10735478" ], "products": [ "species_113550", "species_10735480" ], "modifiers": [ [ "species_10729577", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "SPAC24H6.05" ] }, "reaction_10729374": { "compartment": "compartment_7660", "id": "reaction_10729374", "reactome": "R-SPO-68950", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_30187", "species_29604", "species_29892", "species_10728770" ], "products": [ "species_10729371" ], "modifiers": [ [ "species_10728742", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c" ] }, "reaction_10733290": { "compartment": "compartment_70101", "id": "reaction_10733290", "reactome": "R-SPO-75825", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733288" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P10815", "SPBC582.03", "P0C8R3", "SPAC589.10c", "P25009", "SPBC19F5.01c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10735822": { "compartment": "compartment_7660", "id": "reaction_10735822", "reactome": "R-SPO-187948", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10735523" ], "products": [ "species_113582", "species_10735525" ], "modifiers": [ [ "species_10728937", "catalyst" ] ], "additional_components": [ "SPAC144.13c", "SPAC144.13c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10735825": { "compartment": "compartment_7660", "id": "reaction_10735825", "reactome": "R-SPO-187949", "name": "CAK-mediated phosphorylation of Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10735480" ], "products": [ "species_113582", "species_10728937" ], "modifiers": [ [ "species_10732457", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07" ] }, "reaction_10728773": { "compartment": "compartment_7660", "id": "reaction_10728773", "reactome": "R-SPO-68913", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10728768" ], "products": [ "species_10728764", "species_10728770" ], "modifiers": [ [ "species_10728768", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10733284": { "compartment": "compartment_13231", "id": "reaction_10733284", "reactome": "R-SPO-75822", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733270" ], "products": [ "species_10733282" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10733286": { "compartment": "compartment_13231", "id": "reaction_10733286", "reactome": "R-SPO-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733266" ], "products": [ "species_10733278" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c" ] }, "reaction_10735527": { "compartment": "compartment_13231", "id": "reaction_10735527", "reactome": "R-SPO-174273", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735466" ], "products": [ "species_10735480" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10735468": { "compartment": "compartment_70101", "id": "reaction_10735468", "reactome": "R-SPO-174054", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735434", "species_10729541" ], "products": [ "species_10735466" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "SPBC11B10.09", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10740250": { "compartment": "compartment_70101", "id": "reaction_10740250", "reactome": "R-SPO-549192", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76103", "species_75967" ], "products": [ "species_76194", "species_549167" ], "modifiers": [ [ "species_10740247", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10733412": { "compartment": "compartment_70101", "id": "reaction_10733412", "reactome": "R-SPO-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76108" ], "products": [ "species_76103", "species_29372" ], "modifiers": [ [ "species_10733405", "catalyst" ] ], "additional_components": [ "SPAC1952.13" ] }, "reaction_10752220": { "compartment": "compartment_12045", "id": "reaction_10752220", "reactome": "R-SPO-6800334", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6800352", "species_1500578" ], "products": [ "species_76194", "species_76103" ], "modifiers": [ [ "species_10752213", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10735159": { "compartment": "compartment_70101", "id": "reaction_10735159", "reactome": "R-SPO-165162", "name": "Phosphorylation of TSC2 by PKB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735151" ], "products": [ "species_29370", "species_10735156" ], "modifiers": [ [ "species_10733746", "catalyst" ] ], "additional_components": [ "SPAC630.13c", "SPAC630.13c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c" ] }, "reaction_10735185": { "compartment": "compartment_17938", "id": "reaction_10735185", "reactome": "R-SPO-165195", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10735181" ], "products": [ "species_29420", "species_10735183" ], "modifiers": [], "additional_components": [ "species_29420", "O94363", "SPBC428.16c", "species_29438", "O94363", "SPBC428.16c" ] }, "reaction_10738133": { "compartment": "compartment_70101", "id": "reaction_10738133", "reactome": "R-SPO-380930", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736802", "species_76577" ], "products": [ "species_10738128" ], "modifiers": [], "additional_components": [ "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10735204": { "compartment": "compartment_70101", "id": "reaction_10735204", "reactome": "R-SPO-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731629", "species_113592" ], "products": [ "species_29370", "species_10735201" ], "modifiers": [ [ "species_10735194", "catalyst" ] ], "additional_components": [ "SPAPB1E7.12", "SPAPB1E7.12", "SPCC4G3.08" ] }, "reaction_10757820": { "compartment": "compartment_70101", "id": "reaction_10757820", "reactome": "R-SPO-9679044", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757816", "species_9678687" ], "products": [ "species_10757818" ], "modifiers": [], "additional_components": [ "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c", "species_9678687", "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c" ] }, "reaction_10738131": { "compartment": "compartment_70101", "id": "reaction_10738131", "reactome": "R-SPO-380927", "name": "p-AMPK phosphorylates TSC1:TSC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735168" ], "products": [ "species_29370", "species_10738126" ], "modifiers": [ [ "species_10738128", "catalyst" ] ], "additional_components": [ "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10735211": { "compartment": "compartment_70101", "id": "reaction_10735211", "reactome": "R-SPO-165766", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10731799" ], "products": [ "species_29370", "species_10735209" ], "modifiers": [ [ "species_10735194", "catalyst" ] ], "additional_components": [ "SPAC17C9.03", "SPAC17C9.03", "SPCC4G3.08" ] }, "reaction_10735174": { "compartment": "compartment_70101", "id": "reaction_10735174", "reactome": "R-SPO-165182", "name": "Phosphorylation of complexed TSC2 by PKB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735168" ], "products": [ "species_29370", "species_10735172" ], "modifiers": [ [ "species_10733746", "catalyst" ] ], "additional_components": [ "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c" ] }, "reaction_10746540": { "compartment": "compartment_70101", "id": "reaction_10746540", "reactome": "R-SPO-5653957", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746523", "species_10746536" ], "products": [ "species_10746538" ], "modifiers": [], "additional_components": [ "O74824", "SPBC337.13c", "species_29438", "species_29420", "O74544", "SPCC777.05", "species_29420", "O74544", "SPCC777.05", "O74824", "SPBC337.13c", "species_29438" ] }, "reaction_10741434": { "compartment": "compartment_70101", "id": "reaction_10741434", "reactome": "R-SPO-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741400" ], "products": [ "species_10741402" ], "modifiers": [], "additional_components": [ "SPAC25G10.07c", "P24339", "SPAC25G10.07c" ] }, "reaction_10753183": { "compartment": "compartment_17951", "id": "reaction_10753183", "reactome": "R-SPO-6810076", "name": "DDO oxidizes D-Asp to OA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810061", "species_141343", "species_113535" ], "products": [ "species_389843", "species_6810070", "species_113575" ], "modifiers": [ [ "species_10753180", "catalyst" ] ], "additional_components": [ "Q9Y7N4", "SPCC1450.07c", "species_113596" ] }, "reaction_10749687": { "compartment": "compartment_5460", "id": "reaction_10749687", "reactome": "R-SPO-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10749674" ], "products": [ "species_29362", "species_113529", "species_10749657" ], "modifiers": [ [ "species_10749684", "catalyst" ] ], "additional_components": [ "CHEBI:50746", "Q9HDV9", "SPBP19A11.01", "SPBP19A11.01", "O00087", "SPAC1002.09c", "species_113596" ] }, "reaction_10749682": { "compartment": "compartment_5460", "id": "reaction_10749682", "reactome": "R-SPO-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749661", "species_200671" ], "products": [ "species_5693984", "species_10749674", "species_5693978" ], "modifiers": [ [ "species_10749679", "catalyst" ] ], "additional_components": [ "CHEBI:14949", "Q9HDV9", "SPBP19A11.01", "CHEBI:50746", "Q9HDV9", "SPBP19A11.01", "SPAC31G5.14" ] }, "reaction_10750347": { "compartment": "compartment_5460", "id": "reaction_10750347", "reactome": "R-SPO-6784224", "name": "PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215" ], "products": [ "species_6784241" ], "modifiers": [ [ "species_10750344", "catalyst" ] ], "additional_components": [ "O74524", "SPCC70.03c", "species_113596" ] }, "reaction_10738379": { "compartment": "compartment_17951", "id": "reaction_10738379", "reactome": "R-SPO-389842", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389822", "species_113535" ], "products": [ "species_389678", "species_113575" ], "modifiers": [ [ "species_10738376", "catalyst" ] ], "additional_components": [ "species_73524", "Q9HDX2", "SPAPB1A11.03" ] }, "reaction_10738367": { "compartment": "compartment_17951", "id": "reaction_10738367", "reactome": "R-SPO-389821", "name": "glycine + O2 => glyoxylate + H2O2 + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193446", "species_141343", "species_113535" ], "products": [ "species_389678", "species_389843", "species_113575" ], "modifiers": [ [ "species_10738364", "catalyst" ] ], "additional_components": [ "Q9Y7N4", "SPCC1450.07c", "species_113596" ] }, "reaction_10751187": { "compartment": "compartment_5460", "id": "reaction_10751187", "reactome": "R-SPO-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6793610", "species_2162265", "species_10751177" ], "products": [ "species_6793613", "species_379705", "species_10749657" ], "modifiers": [ [ "species_10751184", "catalyst" ] ], "additional_components": [ "SPBP19A11.01", "SPBP19A11.01", "O13642", "SPBC8D2.15", "CHEBI:49883" ] }, "reaction_10749672": { "compartment": "compartment_5460", "id": "reaction_10749672", "reactome": "R-SPO-5693967", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_10749657" ], "products": [ "species_10749661", "species_29376" ], "modifiers": [ [ "species_10749669", "catalyst" ] ], "additional_components": [ "SPBP19A11.01", "CHEBI:14949", "Q9HDV9", "SPBP19A11.01", "Q09785", "SPAC13G6.06c" ] }, "reaction_10750350": { "compartment": "compartment_5460", "id": "reaction_10750350", "reactome": "R-SPO-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_6784236" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10729968", "catalyst" ] ], "additional_components": [ "O94320", "SPBC725.01" ] }, "reaction_10738382": { "compartment": "compartment_17951", "id": "reaction_10738382", "reactome": "R-SPO-389862", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389678", "species_141343", "species_113535" ], "products": [ "species_389819", "species_113575" ], "modifiers": [ [ "species_10738376", "catalyst" ] ], "additional_components": [ "species_73524", "Q9HDX2", "SPAPB1A11.03" ] }, "reaction_10751156": { "compartment": "compartment_5460", "id": "reaction_10751156", "reactome": "R-SPO-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751146", "species_10749657" ], "products": [ "species_10749659", "species_10751148" ], "modifiers": [ [ "species_10751153", "catalyst" ] ], "additional_components": [ "O94681", "SPBC776.15c", "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "CHEBI:17460", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "O74378", "SPBC3H7.03c", "species_113596", "SPBP19A11.01", "SPBP19A11.01", "O94681", "SPBC776.15c", "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "CHEBI:17460", "O74378", "SPBC3H7.03c", "species_113596", "SPBC17A3.09c" ] }, "reaction_10749950": { "compartment": "compartment_5460", "id": "reaction_10749950", "reactome": "R-SPO-5696408", "name": "PXLP-K278-PHYKPL tetramer hydrolyses 5PHL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_5696409" ], "products": [ "species_113556", "species_113548", "species_5693978" ], "modifiers": [ [ "species_10749947", "catalyst" ] ], "additional_components": [ "Q9US34", "SPAC1039.07c" ] }, "reaction_10737977": { "compartment": "compartment_70101", "id": "reaction_10737977", "reactome": "R-SPO-351948", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737973" ], "products": [ "species_10737975" ], "modifiers": [ [ "species_10737921", "catalyst" ] ], "additional_components": [ "SPAC767.01c", "SPAC767.01c", "SPAC9E9.04" ] }, "reaction_10754771": { "compartment": "compartment_70616", "id": "reaction_10754771", "reactome": "R-SPO-8867344", "name": "OMA1 hydrolyses OPA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754747", "species_113521" ], "products": [ "species_10754763", "species_10754755" ], "modifiers": [ [ "species_10754768", "catalyst" ] ], "additional_components": [ "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "SPAP14E8.04" ] }, "reaction_10747046": { "compartment": "compartment_70101", "id": "reaction_10747046", "reactome": "R-SPO-5675470", "name": "BIRC2/3 (cIAP1/2) is autoubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737150", "species_10747036" ], "products": [ "species_10747039" ], "modifiers": [ [ "species_10737150", "catalyst" ] ], "additional_components": [ "SPCC962.02c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPCC962.02c", "SPCC962.02c" ] }, "reaction_10752633": { "compartment": "compartment_70101", "id": "reaction_10752633", "reactome": "R-SPO-6805811", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752617" ], "products": [ "species_10752631" ], "modifiers": [], "additional_components": [ "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11", "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11" ] }, "reaction_10737755": { "compartment": "compartment_7660", "id": "reaction_10737755", "reactome": "R-SPO-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737751", "species_29428" ], "products": [ "species_10737753" ], "modifiers": [], "additional_components": [ "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c", "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c" ] }, "reaction_10737971": { "compartment": "compartment_13231", "id": "reaction_10737971", "reactome": "R-SPO-351947", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737945" ], "products": [ "species_10737969" ], "modifiers": [], "additional_components": [ "Q10447", "SPAC12B10.14c", "O75011", "SPBC17F3.02", "O14047", "SPAC2C4.14c", "O14305", "SPAC9G1.09", "Q10447", "SPAC12B10.14c", "O75011", "SPBC17F3.02", "O14047", "SPAC2C4.14c", "O14305", "SPAC9G1.09" ] }, "reaction_10757583": { "compartment": "compartment_70101", "id": "reaction_10757583", "reactome": "R-SPO-9641096", "name": "Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757575", "species_10757579" ], "products": [ "species_10757581" ], "modifiers": [], "additional_components": [ "SPAC22E12.03c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10757601": { "compartment": "compartment_70101", "id": "reaction_10757601", "reactome": "R-SPO-9641111", "name": "Parkin transfers Ub to misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757581" ], "products": [ "species_10757599" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10757649": { "compartment": "compartment_18667", "id": "reaction_10757649", "reactome": "R-SPO-9646685", "name": "Aggresome dissociates from dynein and microtubule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757641" ], "products": [ "species_10757647", "species_10738115", "species_10757627" ], "modifiers": [], "additional_components": [ "P04689", "SPBC800.05c", "Q92337", "SPAC9E9.12c", "Q9P3W4", "SPAC458.04c", "Q10356", "SPAC22E12.03c", "P05219", "SPBC26H8.07c", "species_29438", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c", "species_29420", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9P7V2", "SPAC30.04c", "P04688", "SPBC16A3.15c", "O13290", "SPAC1093.06c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04", "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "Q9P3W4", "SPAC458.04c", "O13290", "SPAC1093.06c", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c" ] }, "reaction_10757603": { "compartment": "compartment_70101", "id": "reaction_10757603", "reactome": "R-SPO-9641127", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757599" ], "products": [ "species_10757592" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10757631": { "compartment": "compartment_70101", "id": "reaction_10757631", "reactome": "R-SPO-9646348", "name": "PolyUb-Misfolded Proteins:HDAC6 bind dynein motor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757610", "species_10757627" ], "products": [ "species_10757629" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04", "Q9P3W4", "SPAC458.04c", "O13290", "SPAC1093.06c", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "Q9P3W4", "SPAC458.04c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O13290", "SPAC1093.06c", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04" ] }, "reaction_10730221": { "compartment": "compartment_70101", "id": "reaction_10730221", "reactome": "R-SPO-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10730218", "catalyst" ] ], "additional_components": [ "O42658", "SPAC27D7.04" ] }, "reaction_10740374": { "compartment": "compartment_70101", "id": "reaction_10740374", "reactome": "R-SPO-893593", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29502", "species_29398" ], "products": [ "species_893599", "species_29432" ], "modifiers": [ [ "species_10740371", "catalyst" ] ], "additional_components": [ "O14209", "SPAC6B12.04c" ] }, "reaction_10747288": { "compartment": "compartment_5683628", "id": "reaction_10747288", "reactome": "R-SPO-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747126" ], "products": [ "species_10747279" ], "modifiers": [ [ "species_10740430", "catalyst" ], [ "species_10747286", "catalyst" ] ], "additional_components": [ "O94272", "SPBP8B7.24c", "species_1500581", "O94272", "SPBP8B7.24c", "species_1500581", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O60149", "SPBC18H10.19", "P87117", "SPAC20G8.10c" ] }, "reaction_10747194": { "compartment": "compartment_70101", "id": "reaction_10747194", "reactome": "R-SPO-5681981", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747189" ], "products": [ "species_10747191" ], "modifiers": [ [ "species_10747189", "catalyst" ] ], "additional_components": [ "O43035", "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c", "O43069", "SPBC6B1.05c", "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "O43035", "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c" ] }, "reaction_10746800": { "compartment": "compartment_70101", "id": "reaction_10746800", "reactome": "R-SPO-5672008", "name": "Thr-180 of ULK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746707" ], "products": [ "species_29370", "species_10746797" ], "modifiers": [ [ "species_10746707", "catalyst" ] ], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10757752": { "compartment": "compartment_17947", "id": "reaction_10757752", "reactome": "R-SPO-9664888", "name": "ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757718" ], "products": [ "species_10757740" ], "modifiers": [], "additional_components": [ "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10747085": { "compartment": "compartment_70101", "id": "reaction_10747085", "reactome": "R-SPO-5676229", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747081", "species_5693050" ], "products": [ "species_10747083" ], "modifiers": [], "additional_components": [ "Q9P6N1", "SPAC823.16c", "Q9HDZ7", "SPAC589.07c", "Q9P3W2", "SPAC458.06", "Q9P6N1", "SPAC823.16c", "Q9HDZ7", "SPAC589.07c", "Q9P3W2", "SPAC458.06", "species_1629751" ] }, "reaction_10756472": { "compartment": "compartment_21994", "id": "reaction_10756472", "reactome": "R-SPO-8959571", "name": "LC3 binds the autophagosome membrane Atg5-Atg12 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745146", "species_10756468" ], "products": [ "species_10756470" ], "modifiers": [], "additional_components": [ "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c", "O94272", "SPBP8B7.24c", "O14020", "SPAC29A4.17c", "O94272", "SPBP8B7.24c", "Q9US24", "SPAC1783.06c", "O14020", "SPAC29A4.17c", "O74971", "SPBC4B4.10c" ] }, "reaction_10747385": { "compartment": "compartment_70101", "id": "reaction_10747385", "reactome": "R-SPO-5682690", "name": "ATG10 dissociates from ATG12:ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747383" ], "products": [ "species_10747381", "species_10747137" ], "modifiers": [], "additional_components": [ "Q9US24", "SPAC1783.06c", "Q9UTD5", "SPAC227.04", "O74971", "SPBC4B4.10c", "SPAC227.04", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c" ] }, "reaction_10756095": { "compartment": "compartment_70101", "id": "reaction_10756095", "reactome": "R-SPO-8948039", "name": "FUNDC1 is phosphorylated by CK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756090", "species_113592" ], "products": [ "species_29370", "species_10756093" ], "modifiers": [ [ "species_10743403", "catalyst" ] ], "additional_components": [ "SPAC29A4.17c", "SPAC29A4.17c", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11" ] }, "reaction_10746802": { "compartment": "compartment_70101", "id": "reaction_10746802", "reactome": "R-SPO-5672011", "name": "p-AMPK:AMP binds the ULK complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746699", "species_10738128" ], "products": [ "species_10746701" ], "modifiers": [], "additional_components": [ "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O36019", "SPAC4F10.07c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O74536", "SPCC74.03c", "O36019", "SPAC4F10.07c", "P78789", "SPCC1919.03c" ] }, "reaction_10747172": { "compartment": "compartment_70101", "id": "reaction_10747172", "reactome": "R-SPO-5679239", "name": "ULK complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747055" ], "products": [ "species_10742300" ], "modifiers": [], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "Q9Y7T4", "SPCC63.08c", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10747484": { "compartment": "compartment_70101", "id": "reaction_10747484", "reactome": "R-SPO-5683588", "name": "ATG10 transfers ATG12 from ATG10 to ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747214" ], "products": [ "species_10747383" ], "modifiers": [], "additional_components": [ "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c", "Q9US24", "SPAC1783.06c", "Q9UTD5", "SPAC227.04", "O74971", "SPBC4B4.10c" ] }, "reaction_10747216": { "compartment": "compartment_70101", "id": "reaction_10747216", "reactome": "R-SPO-5682010", "name": "ATG10:ATG12 binds ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747210", "species_10747212" ], "products": [ "species_10747214" ], "modifiers": [], "additional_components": [ "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c", "SPBC4B4.10c", "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c" ] }, "reaction_10757705": { "compartment": "compartment_70101", "id": "reaction_10757705", "reactome": "R-SPO-9664850", "name": "ATM binds PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757061", "species_10757701" ], "products": [ "species_10757703" ], "modifiers": [], "additional_components": [ "SPBC725.07", "SPCC23B6.03c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10747180": { "compartment": "compartment_70101", "id": "reaction_10747180", "reactome": "R-SPO-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747176", "species_10747132" ], "products": [ "species_10747178" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "SPAC1783.06c", "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c" ] }, "reaction_10756108": { "compartment": "compartment_17906", "id": "reaction_10756108", "reactome": "R-SPO-8948146", "name": "FUNDC1 is phosphorylated by ULK1 at Ser17", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756090", "species_113592" ], "products": [ "species_29370", "species_10756105" ], "modifiers": [ [ "species_10756097", "catalyst" ] ], "additional_components": [ "SPAC29A4.17c", "SPAC29A4.17c", "SPCC63.08c" ] }, "reaction_10746710": { "compartment": "compartment_70101", "id": "reaction_10746710", "reactome": "R-SPO-5665868", "name": "AMPK (complex) phosphorylates ULK1 (complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746701", "species_113592" ], "products": [ "species_29370", "species_10746707" ], "modifiers": [ [ "species_10746701", "catalyst" ] ], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O74536", "SPCC74.03c", "O36019", "SPAC4F10.07c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O74536", "SPCC74.03c", "O36019", "SPAC4F10.07c", "P78789", "SPCC1919.03c" ] }, "reaction_10757750": { "compartment": "compartment_70101", "id": "reaction_10757750", "reactome": "R-SPO-9664883", "name": "ATM:PEX5 translocates from cytosol to peroxisomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757703" ], "products": [ "species_10757709" ], "modifiers": [], "additional_components": [ "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10757720": { "compartment": "compartment_17947", "id": "reaction_10757720", "reactome": "R-SPO-9664862", "name": "ATM dimer:PEX5 phosphorylates PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757711" ], "products": [ "species_10757718" ], "modifiers": [], "additional_components": [ "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10747174": { "compartment": "compartment_70101", "id": "reaction_10747174", "reactome": "R-SPO-5679266", "name": "Beclin-1 complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742261" ], "products": [ "species_10747165" ], "modifiers": [], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O42862", "SPAC25A8.02", "P87117", "SPAC20G8.10c" ] }, "reaction_10747146": { "compartment": "compartment_70101", "id": "reaction_10747146", "reactome": "R-SPO-5678490", "name": "ATG16L1 complex transfers LC3 from ATG3 to PE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747124", "species_5681998" ], "products": [ "species_10747128", "species_10747126" ], "modifiers": [ [ "species_10747143", "catalyst" ] ], "additional_components": [ "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "species_1500581", "species_6809774", "Q9HDZ7", "SPAC589.07c", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c" ] }, "reaction_10756099": { "compartment": "compartment_17906", "id": "reaction_10756099", "reactome": "R-SPO-8948136", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746691" ], "products": [ "species_10756097" ], "modifiers": [], "additional_components": [ "SPCC63.08c", "SPCC63.08c" ] }, "reaction_10747268": { "compartment": "compartment_12045", "id": "reaction_10747268", "reactome": "R-SPO-5682385", "name": "The phagophore extends from the PIP3-enriched structure", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746809" ], "products": [ "species_10747259" ], "modifiers": [ [ "species_10747264", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O42862", "SPAC25A8.02", "P87117", "SPAC20G8.10c", "SPBC15D4.07c" ] }, "reaction_10747170": { "compartment": "compartment_70101", "id": "reaction_10747170", "reactome": "R-SPO-5679206", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030" ], "products": [ "species_426639" ], "modifiers": [ [ "species_10742434", "catalyst" ] ], "additional_components": [ "SPAC19A8.03" ] }, "reaction_10747218": { "compartment": "compartment_70101", "id": "reaction_10747218", "reactome": "R-SPO-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747110", "species_10747176" ], "products": [ "species_10747187" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "O43069", "SPBC6B1.05c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c" ] }, "reaction_10747486": { "compartment": "compartment_70101", "id": "reaction_10747486", "reactome": "R-SPO-5683593", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747191" ], "products": [ "species_10747176", "species_10747124" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "O43069", "SPBC6B1.05c", "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c" ] }, "reaction_10757748": { "compartment": "compartment_17947", "id": "reaction_10757748", "reactome": "R-SPO-9664880", "name": "MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747112", "species_10757744" ], "products": [ "species_10757746" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "Q9P792", "SPBP35G2.11c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "Q9P792", "SPBP35G2.11c", "O94272", "SPBP8B7.24c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10756474": { "compartment": "compartment_70101", "id": "reaction_10756474", "reactome": "R-SPO-8959573", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747110", "species_10756105" ], "products": [ "species_10756468" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "SPAC29A4.17c", "O94272", "SPBP8B7.24c", "O14020", "SPAC29A4.17c" ] }, "reaction_10747167": { "compartment": "compartment_70101", "id": "reaction_10747167", "reactome": "R-SPO-5679205", "name": "ULK1 phosphorylates Beclin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10747165" ], "products": [ "species_29370", "species_10746809" ], "modifiers": [ [ "species_10742300", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O42862", "SPAC25A8.02", "P87117", "SPAC20G8.10c", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10747524": { "compartment": "compartment_70101", "id": "reaction_10747524", "reactome": "R-SPO-5683925", "name": "ULK1 is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747522" ], "products": [ "species_10746699", "species_29372" ], "modifiers": [], "additional_components": [ "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O36019", "SPAC4F10.07c" ] }, "reaction_10747431": { "compartment": "compartment_70101", "id": "reaction_10747431", "reactome": "R-SPO-5682896", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747128", "species_10747187" ], "products": [ "species_10747189" ], "modifiers": [], "additional_components": [ "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c", "O43035", "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c" ] }, "reaction_10757731": { "compartment": "compartment_17947", "id": "reaction_10757731", "reactome": "R-SPO-9664879", "name": "ATM:PEX5 binds ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757707", "species_10757709" ], "products": [ "species_10757711" ], "modifiers": [ [ "species_1250243", "catalyst" ] ], "additional_components": [ "SPCC23B6.03c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10746812": { "compartment": "compartment_12045", "id": "reaction_10746812", "reactome": "R-SPO-5672012", "name": "Beclin-1 complex phosphorylates PtdIns", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_5676030", "species_29370" ], "modifiers": [ [ "species_10746809", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02" ] }, "reaction_10747429": { "compartment": "compartment_70101", "id": "reaction_10747429", "reactome": "R-SPO-5682893", "name": "ATG12:ATG7:CysO572-ATG7 binds ATG10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747425", "species_10747381" ], "products": [ "species_10747427" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c", "SPAC227.04", "O43069", "SPBC6B1.05c", "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c" ] }, "reaction_10742303": { "compartment": "compartment_70101", "id": "reaction_10742303", "reactome": "R-SPO-1632857", "name": "ULK1 phosphorylates AMBRA1:BECN1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742263", "species_113592" ], "products": [ "species_10742269", "species_29370" ], "modifiers": [ [ "species_10742300", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "Q9UR05", "SPAC926.07c", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "Q9UR05", "SPAC926.07c", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10747058": { "compartment": "compartment_70101", "id": "reaction_10747058", "reactome": "R-SPO-5675868", "name": "ULK1 phosphorylates ATG13 and RB1CC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746797", "species_113592" ], "products": [ "species_29370", "species_10747055" ], "modifiers": [ [ "species_10746797", "catalyst" ] ], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "Q9Y7T4", "SPCC63.08c", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10757729": { "compartment": "compartment_17947", "id": "reaction_10757729", "reactome": "R-SPO-9664867", "name": "NBR1 binds MAP1LC3B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747112", "species_10757725" ], "products": [ "species_10757727" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "SPBP35G2.11c", "Q9P792", "SPBP35G2.11c", "O94272", "SPBP8B7.24c" ] }, "reaction_10756986": { "compartment": "compartment_70101", "id": "reaction_10756986", "reactome": "R-SPO-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747178" ], "products": [ "species_10747425" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c", "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c" ] }, "reaction_10733817": { "compartment": "compartment_70101", "id": "reaction_10733817", "reactome": "R-SPO-109864", "name": "Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733810" ], "products": [ "species_10733776", "species_10733808" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "SPAC1D4.13", "SPAC31G5.09c" ] }, "reaction_10757664": { "compartment": "compartment_876", "id": "reaction_10757664", "reactome": "R-SPO-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10737221" ], "products": [ "species_10757662" ], "modifiers": [], "additional_components": [ "O42881", "SPAC8E11.04c", "species_9647934", "O42881", "SPAC8E11.04c" ] }, "reaction_10746851": { "compartment": "compartment_20699", "id": "reaction_10746851", "reactome": "R-SPO-5674373", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746846" ], "products": [ "species_29370", "species_10746848" ], "modifiers": [ [ "species_10746846", "catalyst" ] ], "additional_components": [ "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10733772": { "compartment": "compartment_70101", "id": "reaction_10733772", "reactome": "R-SPO-109857", "name": "MAP2K1 binds MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733756", "species_10733768" ], "products": [ "species_10733770" ], "modifiers": [], "additional_components": [ "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08" ] }, "reaction_10757671": { "compartment": "compartment_12045", "id": "reaction_10757671", "reactome": "R-SPO-9653514", "name": "USP17L2 deubiquitinates RCE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757666", "species_29356" ], "products": [ "species_10757668", "species_10749260" ], "modifiers": [ [ "species_10749999", "catalyst" ] ], "additional_components": [ "SPAC1687.02", "SPAC1687.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPCC1682.12c" ] }, "reaction_10746325": { "compartment": "compartment_70101", "id": "reaction_10746325", "reactome": "R-SPO-5627775", "name": "Autophosphorylation of PAK1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746306" ], "products": [ "species_29370", "species_10746322", "species_10738231" ], "modifiers": [ [ "species_10746306", "catalyst" ] ], "additional_components": [ "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c" ] }, "reaction_10757660": { "compartment": "compartment_70101", "id": "reaction_10757660", "reactome": "R-SPO-9647987", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9653479", "species_10757656" ], "products": [ "species_10757658" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "LigandDisplayForward?ligandId=8030", "O13782", "SPAC17G6.04c", "O60052", "SPAPB1A10.04c", "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "O13782", "SPAC17G6.04c", "O60052", "SPAPB1A10.04c", "LigandDisplayForward?ligandId=8030" ] }, "reaction_10746861": { "compartment": "compartment_7660", "id": "reaction_10746861", "reactome": "R-SPO-5674387", "name": "Phosphorylated MAPKs translocate into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746855" ], "products": [ "species_10746859" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10733782": { "compartment": "compartment_70101", "id": "reaction_10733782", "reactome": "R-SPO-109858", "name": "MAP2K2 binds MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733778", "species_10733776" ], "products": [ "species_10733780" ], "modifiers": [], "additional_components": [ "SPAC31G5.09c", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13" ] }, "reaction_10733815": { "compartment": "compartment_70101", "id": "reaction_10733815", "reactome": "R-SPO-109863", "name": "Dissociation of p-T,Y-MAPK3:MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733794" ], "products": [ "species_10733792", "species_10733756" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPAC1D4.13" ] }, "reaction_10754546": { "compartment": "compartment_7660", "id": "reaction_10754546", "reactome": "R-SPO-8856945", "name": "PP2A methylation by LCMT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754531", "species_77087" ], "products": [ "species_10754538", "species_77502" ], "modifiers": [ [ "species_10754543", "catalyst" ] ], "additional_components": [ "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "SPBP8B7.08c" ] }, "reaction_10735452": { "compartment": "compartment_13231", "id": "reaction_10735452", "reactome": "R-SPO-170159", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735448" ], "products": [ "species_10735450" ], "modifiers": [], "additional_components": [ "P06652", "SPAC24H6.05", "P06652", "SPAC24H6.05" ] }, "reaction_10754554": { "compartment": "compartment_7660", "id": "reaction_10754554", "reactome": "R-SPO-8856951", "name": "PP2A demethylation by PPME1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10754538" ], "products": [ "species_8857797", "species_10754531" ], "modifiers": [ [ "species_10754551", "catalyst" ] ], "additional_components": [ "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "SPBP4H10.17c" ] }, "reaction_10734633": { "compartment": "compartment_7660", "id": "reaction_10734633", "reactome": "R-SPO-156678", "name": "Activation of Cdc25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734625" ], "products": [ "species_29370", "species_10734628" ], "modifiers": [ [ "species_10734630", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC23C11.16" ] }, "reaction_10735444": { "compartment": "compartment_13231", "id": "reaction_10735444", "reactome": "R-SPO-170149", "name": "Translocation of active Cdc25C to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734628" ], "products": [ "species_10735442" ], "modifiers": [], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05" ] }, "reaction_10735440": { "compartment": "compartment_13231", "id": "reaction_10735440", "reactome": "R-SPO-170120", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735436" ], "products": [ "species_10735438" ], "modifiers": [], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05" ] }, "reaction_10743753": { "compartment": "compartment_70101", "id": "reaction_10743753", "reactome": "R-SPO-3002798", "name": "Cytosolic PLK1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734630" ], "products": [ "species_10734620" ], "modifiers": [], "additional_components": [ "SPAC23C11.16", "SPAC23C11.16" ] }, "reaction_10734775": { "compartment": "compartment_7660", "id": "reaction_10734775", "reactome": "R-SPO-162657", "name": "Inactivation of Myt1 kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10734770" ], "products": [ "species_113582", "species_10734773" ], "modifiers": [ [ "species_10734620", "catalyst" ] ], "additional_components": [ "SPAC23C11.16" ] }, "reaction_10743650": { "compartment": "compartment_7660", "id": "reaction_10743650", "reactome": "R-SPO-2993780", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743639", "species_10743587" ], "products": [ "species_10743647", "species_10743572" ], "modifiers": [ [ "species_10743572", "catalyst" ] ], "additional_components": [ "SPAC30D11.13", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04" ] }, "reaction_10743604": { "compartment": "compartment_7660", "id": "reaction_10743604", "reactome": "R-SPO-2990840", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743592" ], "products": [ "species_10743577" ], "modifiers": [ [ "species_10743597", "catalyst" ] ], "additional_components": [ "SPBC365.06", "SPBC365.06", "SPBC19G7.09" ] }, "reaction_10743590": { "compartment": "compartment_7660", "id": "reaction_10743590", "reactome": "R-SPO-2990833", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10743577", "species_10743572" ], "products": [ "species_10743587", "species_164121", "species_113541" ], "modifiers": [ [ "species_10743572", "catalyst" ] ], "additional_components": [ "SPBC365.06", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O13351", "SPBC365.06", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04" ] }, "reaction_10749697": { "compartment": "compartment_70101", "id": "reaction_10749697", "reactome": "R-SPO-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5694074" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10749694", "catalyst" ] ], "additional_components": [ "species_442320", "Q09751", "SPBC12C2.12c" ] }, "reaction_10739914": { "compartment": "compartment_5460", "id": "reaction_10739914", "reactome": "R-SPO-450975", "name": "isocitrate <=> citrate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938" ], "products": [ "species_29654" ], "modifiers": [ [ "species_10730103", "catalyst" ] ], "additional_components": [ "SPAC24C9.06c" ] }, "reaction_10737284": { "compartment": "compartment_5460", "id": "reaction_10737284", "reactome": "R-SPO-203946", "name": "PDK isoforms phosphorylate lipo-PDH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_10730323" ], "products": [ "species_10737268", "species_113581" ], "modifiers": [ [ "species_10737273", "catalyst" ], [ "species_113559", "catalyst" ], [ "species_29362", "catalyst" ], [ "species_113557", "inhibitor" ], [ "species_10737282", "inhibitor" ] ], "additional_components": [ "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "species_113596", "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "species_113596", "SPAC644.11c", "species_9010792", "Q9P6P9", "SPAC644.11c" ] }, "reaction_10730326": { "compartment": "compartment_5460", "id": "reaction_10730326", "reactome": "R-SPO-71397", "name": "lipo-PDH decarboxylates PYR to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113557", "species_113526" ], "products": [ "species_29376", "species_29362", "species_113559" ], "modifiers": [ [ "species_10730323", "catalyst" ] ], "additional_components": [ "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "species_113596" ] }, "reaction_10756610": { "compartment": "compartment_5460", "id": "reaction_10756610", "reactome": "R-SPO-9011543", "name": "DCA binds PDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9010792", "species_10737275" ], "products": [ "species_10737282" ], "modifiers": [], "additional_components": [ "SPAC644.11c", "species_9010792", "Q9P6P9", "SPAC644.11c" ] }, "reaction_10735422": { "compartment": "compartment_5460", "id": "reaction_10735422", "reactome": "R-SPO-169270", "name": "ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_10735411" ], "products": [ "species_76633", "species_10735409" ], "modifiers": [ [ "species_10735419", "catalyst" ] ], "additional_components": [ "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_31649", "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_113596", "SPAC20G8.04c" ] }, "reaction_10730165": { "compartment": "compartment_5460", "id": "reaction_10730165", "reactome": "R-SPO-70994", "name": "Succinate <=> Fumarate (with FAD redox reaction on enzyme)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113536" ], "products": [ "species_113588" ], "modifiers": [ [ "species_10730162", "catalyst" ] ], "additional_components": [ "Q9P7X0", "SPBP23A10.16", "Q9UTJ7", "SPAC1556.02c", "O74882", "SPCC330.12c", "P21911", "SPAC140.01", "species_113596" ] }, "reaction_10730116": { "compartment": "compartment_5460", "id": "reaction_10730116", "reactome": "R-SPO-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113587", "species_113559" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10730113", "catalyst" ] ], "additional_components": [ "Q10306", "SPAC6C3.04" ] }, "reaction_10757797": { "compartment": "compartment_984", "id": "reaction_10757797", "reactome": "R-SPO-9673054", "name": "PM20D1 hydrolyzes oleoyl-phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9673044", "species_109276" ], "products": [ "species_351993", "species_9673048" ], "modifiers": [ [ "species_10757792", "catalyst" ] ], "additional_components": [ "SPAC24C9.08" ] }, "reaction_10752715": { "compartment": "compartment_5460", "id": "reaction_10752715", "reactome": "R-SPO-6807826", "name": "LDHAL6B reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113557", "species_113529" ], "products": [ "species_113526", "species_6807616" ], "modifiers": [ [ "species_10752712", "catalyst" ] ], "additional_components": [ "SPAC186.08c" ] }, "reaction_10750305": { "compartment": "compartment_70101", "id": "reaction_10750305", "reactome": "R-SPO-6783221", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694130" ], "products": [ "species_29450", "species_29708" ], "modifiers": [ [ "species_10750302", "catalyst" ] ], "additional_components": [ "species_442320", "Q9UT36", "SPAC824.07" ] }, "reaction_10730098": { "compartment": "compartment_5460", "id": "reaction_10730098", "reactome": "R-SPO-70967", "name": "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938", "species_113526" ], "products": [ "species_113594", "species_29376", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730095", "catalyst" ], [ "species_113581", "catalyst" ] ], "additional_components": [ "O13696", "SPAC11G7.03", "species_113527", "Q9USP8", "SPBC902.05c" ] }, "reaction_10730607": { "compartment": "compartment_70101", "id": "reaction_10730607", "reactome": "R-SPO-71849", "name": "LDH tetramer reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_29398" ], "products": [ "species_29708", "species_29360" ], "modifiers": [ [ "species_10729885", "catalyst" ] ], "additional_components": [ "Q9P7P7", "SPAC186.08c" ] }, "reaction_10735414": { "compartment": "compartment_5460", "id": "reaction_10735414", "reactome": "R-SPO-169260", "name": "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735409", "species_31649" ], "products": [ "species_113596", "species_10735411" ], "modifiers": [ [ "species_10735409", "catalyst" ] ], "additional_components": [ "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_113596", "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_31649", "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_113596" ] }, "reaction_10739916": { "compartment": "compartment_5460", "id": "reaction_10739916", "reactome": "R-SPO-451033", "name": "(S)-Malate <=> Fumarate + H2O", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113544" ], "products": [ "species_113521", "species_113588" ], "modifiers": [ [ "species_10730133", "catalyst" ] ], "additional_components": [ "O94552", "SPCC18.18c" ] }, "reaction_10756661": { "compartment": "compartment_70101", "id": "reaction_10756661", "reactome": "R-SPO-9012374", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398" ], "products": [ "species_9012375" ], "modifiers": [ [ "species_10745156", "catalyst" ] ], "additional_components": [ "SPAC1635.01" ] }, "reaction_10730180": { "compartment": "compartment_5460", "id": "reaction_10730180", "reactome": "R-SPO-70997", "name": "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_70958" ], "products": [ "species_29374", "species_113536", "species_113593" ], "modifiers": [ [ "species_10730177", "catalyst" ] ], "additional_components": [ "O13750", "SPAC16E8.17c", "O94415", "SPCC1620.08" ] }, "reaction_10735047": { "compartment": "compartment_70616", "id": "reaction_10735047", "reactome": "R-SPO-164651", "name": "Electron transfer from ubiquinol to cytochrome c of complex III", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76633", "species_10734930", "species_113529", "species_73663" ], "products": [ "species_76633", "species_10734928", "species_163953", "species_73663" ], "modifiers": [ [ "species_10735044", "catalyst" ] ], "additional_components": [ "P00046", "SPCC191.07", "CHEBI:38574", "P00046", "SPCC191.07", "CHEBI:38573", "Q9P7X1", "SPBP23A10.15c", "Q09154", "SPBC16H5.06", "O42932", "SPBC16C6.08c", "P05501", "SPMIT.05", "P50523", "SPAC1782.07", "O74533", "SPCC737.02c", "O59680", "SPBC29A3.18", "O94745", "SPBC18E5.12c", "O74433", "SPCC1682.01" ] }, "reaction_10729888": { "compartment": "compartment_70101", "id": "reaction_10729888", "reactome": "R-SPO-70510", "name": "LDH tetramer oxidises LACT to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_29360" ], "products": [ "species_70106", "species_73473", "species_29398" ], "modifiers": [ [ "species_10729885", "catalyst" ] ], "additional_components": [ "Q9P7P7", "SPAC186.08c" ] }, "reaction_10756645": { "compartment": "compartment_5460", "id": "reaction_10756645", "reactome": "R-SPO-9012016", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587" ], "products": [ "species_29376", "species_113557" ], "modifiers": [ [ "species_10756642", "catalyst" ] ], "additional_components": [ "species_29926", "Q9P7L4", "SPBC21C3.09c" ] }, "reaction_10730328": { "compartment": "compartment_5460", "id": "reaction_10730328", "reactome": "R-SPO-71401", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113594", "species_113526" ], "products": [ "species_29376", "species_70958", "species_29362" ], "modifiers": [ [ "species_10730208", "catalyst" ] ], "additional_components": [ "O94681", "SPBC776.15c", "species_29480", "O00087", "SPAC1002.09c", "CHEBI:17460", "O74378", "SPBC3H7.03c", "species_113596" ] }, "reaction_10740353": { "compartment": "compartment_5460", "id": "reaction_10740353", "reactome": "R-SPO-880007", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_879997" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10740350", "catalyst" ], [ "species_880069", "catalyst" ], [ "species_113527", "catalyst" ], [ "species_880067", "catalyst" ] ], "additional_components": [ "SPBC713.03" ] }, "reaction_10757795": { "compartment": "compartment_984", "id": "reaction_10757795", "reactome": "R-SPO-9673053", "name": "PM20D1 transforms oleoyl-phe from oleate and phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351993", "species_9673048" ], "products": [ "species_9673044", "species_109276" ], "modifiers": [ [ "species_10757792", "catalyst" ] ], "additional_components": [ "SPAC24C9.08" ] }, "reaction_10736322": { "compartment": "compartment_70101", "id": "reaction_10736322", "reactome": "R-SPO-194678", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194634", "species_29368" ], "products": [ "species_29366", "species_194644", "species_29460", "species_29356" ], "modifiers": [ [ "species_10736319", "catalyst" ] ], "additional_components": [ "SPAC13A11.02c" ] }, "reaction_10742192": { "compartment": "compartment_161320", "id": "reaction_10742192", "reactome": "R-SPO-1605736", "name": "Alpha-galactosidase A removes a terminal galactose from alpha-D-galactoside oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605716", "species_1605715" ], "products": [ "species_1605601", "species_1605637" ], "modifiers": [ [ "species_10742189", "catalyst" ] ], "additional_components": [ "Q9URZ0", "SPAC869.07c" ] }, "reaction_10742202": { "compartment": "compartment_876", "id": "reaction_10742202", "reactome": "R-SPO-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10742199", "catalyst" ] ], "additional_components": [ "O74369", "SPBC32F12.01c", "species_29926" ] }, "reaction_10742308": { "compartment": "compartment_876", "id": "reaction_10742308", "reactome": "R-SPO-1640164", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10742305", "catalyst" ] ], "additional_components": [ "SPBC725.05c" ] }, "reaction_10745892": { "compartment": "compartment_70101", "id": "reaction_10745892", "reactome": "R-SPO-5362721", "name": "RDH5,RDH11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_30927" ], "products": [ "species_70106", "species_73473", "species_32737" ], "modifiers": [ [ "species_10745889", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10745878": { "compartment": "compartment_70101", "id": "reaction_10745878", "reactome": "R-SPO-5362522", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975622", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_5334816" ], "modifiers": [ [ "species_10745875", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10745907": { "compartment": "compartment_70101", "id": "reaction_10745907", "reactome": "R-SPO-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10745904", "catalyst" ] ], "additional_components": [ "O74959", "SPCC736.13", "O13822", "SPCC736.13" ] }, "reaction_10745865": { "compartment": "compartment_70101", "id": "reaction_10745865", "reactome": "R-SPO-5362518", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10745862", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10746047": { "compartment": "compartment_70101", "id": "reaction_10746047", "reactome": "R-SPO-5615668", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10745883": { "compartment": "compartment_70101", "id": "reaction_10745883", "reactome": "R-SPO-5362564", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10745880", "catalyst" ] ], "additional_components": [ "species_442320", "P78870", "SPCC13B11.04c", "O74540", "SPCC13B11.04c" ] }, "reaction_10737563": { "compartment": "compartment_7660", "id": "reaction_10737563", "reactome": "R-SPO-212263", "name": "PRC2 trimethylates histone H3 at lysine-27", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10737551" ], "products": [ "species_10737560", "species_77502" ], "modifiers": [ [ "species_10737551", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c" ] }, "reaction_10745441": { "compartment": "compartment_7660", "id": "reaction_10745441", "reactome": "R-SPO-5220959", "name": "TDG excises 5-formylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5221062", "species_10733857" ], "products": [ "species_10733889", "species_5221065" ], "modifiers": [ [ "species_10733857", "catalyst" ] ], "additional_components": [ "SPCC965.05c", "O59825", "SPCC965.05c", "SPCC965.05c" ] }, "reaction_10745443": { "compartment": "compartment_7660", "id": "reaction_10745443", "reactome": "R-SPO-5221061", "name": "TDG excises 5-carboxylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5220996", "species_10733857" ], "products": [ "species_5221064", "species_10733889" ], "modifiers": [ [ "species_10733857", "catalyst" ] ], "additional_components": [ "SPCC965.05c", "O59825", "SPCC965.05c", "SPCC965.05c" ] }, "reaction_10749501": { "compartment": "compartment_70101", "id": "reaction_10749501", "reactome": "R-SPO-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735397" ], "products": [ "species_10735395" ], "modifiers": [ [ "species_10729170", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPAC31G5.13" ] }, "reaction_10749588": { "compartment": "compartment_70101", "id": "reaction_10749588", "reactome": "R-SPO-5693061", "name": "STAMBP binds STAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749579", "species_10749584" ], "products": [ "species_10749586" ], "modifiers": [], "additional_components": [ "O74749", "SPBC1734.08", "O94478", "SPCC1919.11", "SPAC19B12.10", "O74749", "SPBC1734.08", "Q9P371", "SPAC19B12.10", "O94478", "SPCC1919.11" ] }, "reaction_10749982": { "compartment": "compartment_70101", "id": "reaction_10749982", "reactome": "R-SPO-5696547", "name": "STAMBPL1 is a deubiquitinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735397" ], "products": [ "species_10735395" ], "modifiers": [ [ "species_10749979", "catalyst" ], [ "species_10749586", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPAC19B12.10", "O74749", "SPBC1734.08", "Q9P371", "SPAC19B12.10", "O94478", "SPCC1919.11" ] }, "reaction_10736864": { "compartment": "compartment_876", "id": "reaction_10736864", "reactome": "R-SPO-200646", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965" ], "products": [ "species_200716" ], "modifiers": [ [ "species_10736861", "catalyst" ] ], "additional_components": [ "SPAC14C4.07" ] }, "reaction_10736856": { "compartment": "compartment_70101", "id": "reaction_10736856", "reactome": "R-SPO-200644", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_200739" ], "products": [ "species_70106", "species_29364", "species_200640" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10744081": { "compartment": "compartment_70101", "id": "reaction_10744081", "reactome": "R-SPO-3323111", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743659" ], "products": [ "species_10743759" ], "modifiers": [], "additional_components": [ "Q9UUE1", "SPBC17G9.11c", "species_113527", "Q9UUE1", "SPBC17G9.11c", "species_113527" ] }, "reaction_10749713": { "compartment": "compartment_70616", "id": "reaction_10749713", "reactome": "R-SPO-5694137", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693984", "species_113521", "species_159549" ], "products": [ "species_200671", "species_379732" ], "modifiers": [ [ "species_10749710", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c", "O13972", "SPAC24C9.12c" ] }, "reaction_10736843": { "compartment": "compartment_7660", "id": "reaction_10736843", "reactome": "R-SPO-200512", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_200492" ], "products": [ "species_200499", "species_113541" ], "modifiers": [ [ "species_10736840", "catalyst" ] ], "additional_components": [ "species_442320", "Q9UT53", "SPAC806.06c" ] }, "reaction_10740902": { "compartment": "compartment_70101", "id": "reaction_10740902", "reactome": "R-SPO-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965053", "species_113592" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10740897", "catalyst" ] ], "additional_components": [ "species_442320", "O14242", "SPAC6F6.11c" ] }, "reaction_10736380": { "compartment": "compartment_70101", "id": "reaction_10736380", "reactome": "R-SPO-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196767", "species_113592" ], "products": [ "species_196778", "species_111294" ], "modifiers": [ [ "species_10736377", "catalyst" ] ], "additional_components": [ "SPAC1F12.08" ] }, "reaction_10736449": { "compartment": "compartment_70101", "id": "reaction_10736449", "reactome": "R-SPO-197958", "name": "FPGS-2 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_111355" ], "products": [ "species_29370", "species_197969", "species_29372" ], "modifiers": [ [ "species_10736446", "catalyst" ] ], "additional_components": [ "SPBC1709.17" ] }, "reaction_10755126": { "compartment": "compartment_70101", "id": "reaction_10755126", "reactome": "R-SPO-8869633", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10755112", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10743762": { "compartment": "compartment_70101", "id": "reaction_10743762", "reactome": "R-SPO-3095901", "name": "ABCC1 transports cytosolic Cbl to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3000241", "species_29356" ], "products": [ "species_29370", "species_3000125", "species_29372" ], "modifiers": [ [ "species_10737726", "catalyst" ] ], "additional_components": [ "SPAC3F10.11c" ] }, "reaction_10736897": { "compartment": "compartment_70101", "id": "reaction_10736897", "reactome": "R-SPO-200711", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29460", "species_197969" ], "products": [ "species_29370", "species_111353", "species_29372" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10736901": { "compartment": "compartment_70616", "id": "reaction_10736901", "reactome": "R-SPO-200720", "name": "SLC25A32 transports THF from mitochondrial matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671" ], "products": [ "species_111355" ], "modifiers": [ [ "species_10736884", "catalyst" ] ], "additional_components": [ "SPBC27B12.09c" ] }, "reaction_10736383": { "compartment": "compartment_70101", "id": "reaction_10736383", "reactome": "R-SPO-196773", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196778" ], "products": [ "species_76194", "species_29370" ], "modifiers": [ [ "species_10736377", "catalyst" ] ], "additional_components": [ "SPAC1F12.08" ] }, "reaction_10740904": { "compartment": "compartment_70101", "id": "reaction_10740904", "reactome": "R-SPO-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965131", "species_113592" ], "products": [ "species_29370", "species_29390" ], "modifiers": [ [ "species_10740897", "catalyst" ] ], "additional_components": [ "species_442320", "O14242", "SPAC6F6.11c" ] }, "reaction_10744750": { "compartment": "compartment_70101", "id": "reaction_10744750", "reactome": "R-SPO-4167511", "name": "HLCS biotinylates ACACB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_10744748", "species_113592" ], "products": [ "species_111294", "species_76577", "species_10736807" ], "modifiers": [ [ "species_10743664", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527", "P78820", "SPAC56E4.04c", "species_113527", "SPBC30D10.07c" ] }, "reaction_10736866": { "compartment": "compartment_70101", "id": "reaction_10736866", "reactome": "R-SPO-200651", "name": "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_200739" ], "products": [ "species_200736", "species_197969" ], "modifiers": [ [ "species_10730229", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c" ] }, "reaction_10740888": { "compartment": "compartment_70101", "id": "reaction_10740888", "reactome": "R-SPO-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740872", "species_111707" ], "products": [ "species_10740877", "species_29432" ], "modifiers": [ [ "species_10740885", "catalyst" ] ], "additional_components": [ "species_442320", "Q09810", "SPAC2G11.10c", "species_442320", "Q09810", "SPAC2G11.10c", "O74351", "SPBC21D10.11c" ] }, "reaction_10740914": { "compartment": "compartment_70101", "id": "reaction_10740914", "reactome": "R-SPO-965019", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964952", "species_29368" ], "products": [ "species_29408", "species_29390" ], "modifiers": [ [ "species_10740911", "catalyst" ] ], "additional_components": [ "Q9UTQ1", "SPAC1093.02", "species_73524" ] }, "reaction_10736894": { "compartment": "compartment_5460", "id": "reaction_10736894", "reactome": "R-SPO-200682", "name": "Mitochondrial FPGS-1 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_200671", "species_113593" ], "products": [ "species_113548", "species_200679", "species_113581" ], "modifiers": [ [ "species_10736891", "catalyst" ] ], "additional_components": [ "SPBC1709.17" ] }, "reaction_10736836": { "compartment": "compartment_5460", "id": "reaction_10736836", "reactome": "R-SPO-200474", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938083", "species_113593" ], "products": [ "species_8938090", "species_159450" ], "modifiers": [ [ "species_10736833", "catalyst" ] ], "additional_components": [ "Q9UT53", "SPAC806.06c", "species_29926" ] }, "reaction_10740900": { "compartment": "compartment_70101", "id": "reaction_10740900", "reactome": "R-SPO-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10740897", "catalyst" ] ], "additional_components": [ "species_442320", "O14242", "SPAC6F6.11c" ] }, "reaction_10736905": { "compartment": "compartment_70101", "id": "reaction_10736905", "reactome": "R-SPO-200735", "name": "SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_197969" ], "products": [ "species_29424", "species_200739" ], "modifiers": [ [ "species_10730229", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c" ] }, "reaction_10736907": { "compartment": "compartment_70101", "id": "reaction_10736907", "reactome": "R-SPO-200740", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200640", "species_29356" ], "products": [ "species_111353" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10752500": { "compartment": "compartment_5460", "id": "reaction_10752500", "reactome": "R-SPO-6801456", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5389850", "species_113548", "species_113581" ], "products": [ "species_200671", "species_6801451", "species_113593" ], "modifiers": [ [ "species_10750054", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16", "O43007", "SPBC2G2.08" ] }, "reaction_10736658": { "compartment": "compartment_70101", "id": "reaction_10736658", "reactome": "R-SPO-198845", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736644", "species_1497805" ], "products": [ "species_198816", "species_10736642" ], "modifiers": [ [ "species_10736644", "catalyst" ] ], "additional_components": [ "species_189444", "Q9USM6", "SPCC16A11.10c", "CHEBI:36144", "Q9USM6", "SPCC16A11.10c", "species_189444", "Q9USM6", "SPCC16A11.10c" ] }, "reaction_10736899": { "compartment": "compartment_70101", "id": "reaction_10736899", "reactome": "R-SPO-200718", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200640" ], "products": [ "species_29366", "species_200739" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10743673": { "compartment": "compartment_70101", "id": "reaction_10743673", "reactome": "R-SPO-2993814", "name": "HLCS biotinylates ACACA:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_10743671", "species_113592" ], "products": [ "species_10733321", "species_111294", "species_76577" ], "modifiers": [ [ "species_10743664", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527", "P78820", "SPAC56E4.04c", "species_113527", "SPBC30D10.07c" ] }, "reaction_10736431": { "compartment": "compartment_70101", "id": "reaction_10736431", "reactome": "R-SPO-197235", "name": "NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_197220" ], "products": [ "species_197256", "species_111294" ], "modifiers": [ [ "species_10736428", "catalyst" ] ], "additional_components": [ "Q9UT53", "SPAC806.06c", "species_29926" ] }, "reaction_10736372": { "compartment": "compartment_70101", "id": "reaction_10736372", "reactome": "R-SPO-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111707", "species_196786" ], "products": [ "species_196834", "species_111294", "species_76577" ], "modifiers": [ [ "species_10736369", "catalyst" ] ], "additional_components": [ "Q9USK7", "SPCC4B3.18" ] }, "reaction_10740916": { "compartment": "compartment_70101", "id": "reaction_10740916", "reactome": "R-SPO-965079", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965146", "species_29368", "species_29356" ], "products": [ "species_29408", "species_31633", "species_29390" ], "modifiers": [ [ "species_10740911", "catalyst" ] ], "additional_components": [ "Q9UTQ1", "SPAC1093.02", "species_73524" ] }, "reaction_10736441": { "compartment": "compartment_70101", "id": "reaction_10736441", "reactome": "R-SPO-197271", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197256", "species_29472", "species_113592", "species_29356" ], "products": [ "species_29404", "species_111294", "species_29360", "species_76577" ], "modifiers": [ [ "species_10736438", "catalyst" ] ], "additional_components": [ "O74940", "SPCC553.02" ] }, "reaction_10743667": { "compartment": "compartment_70101", "id": "reaction_10743667", "reactome": "R-SPO-2993802", "name": "HLCS biotinylates PC:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_113592", "species_10743654" ], "products": [ "species_10743659", "species_111294", "species_76577" ], "modifiers": [ [ "species_10743664", "catalyst" ] ], "additional_components": [ "Q9UUE1", "SPBC17G9.11c", "species_113527", "Q9UUE1", "SPBC17G9.11c", "species_113527", "SPBC30D10.07c" ] }, "reaction_10736903": { "compartment": "compartment_876", "id": "reaction_10736903", "reactome": "R-SPO-200729", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716" ], "products": [ "species_197965" ], "modifiers": [ [ "species_10736861", "catalyst" ] ], "additional_components": [ "SPAC14C4.07" ] }, "reaction_10752956": { "compartment": "compartment_70101", "id": "reaction_10752956", "reactome": "R-SPO-6808496", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_111353", "species_29356" ], "products": [ "species_70106", "species_29364", "species_113528", "species_197969" ], "modifiers": [ [ "species_10752953", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10752498": { "compartment": "compartment_70101", "id": "reaction_10752498", "reactome": "R-SPO-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_70106", "species_29370", "species_200640", "species_29372" ], "modifiers": [ [ "species_10752495", "catalyst" ] ], "additional_components": [ "SPBC1703.08c" ] }, "reaction_10757959": { "compartment": "compartment_70101", "id": "reaction_10757959", "reactome": "R-SPO-9709098", "name": "DHFR dimer reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_197965" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10757956", "catalyst" ] ], "additional_components": [ "P36591", "SPCC1223.08c" ] }, "reaction_10755120": { "compartment": "compartment_70101", "id": "reaction_10755120", "reactome": "R-SPO-8869607", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10755117", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10750057": { "compartment": "compartment_5460", "id": "reaction_10750057", "reactome": "R-SPO-5696839", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_6801451", "species_113593" ], "products": [ "species_5389850", "species_113548", "species_113581" ], "modifiers": [ [ "species_10750054", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16", "O43007", "SPBC2G2.08" ] }, "reaction_10736457": { "compartment": "compartment_70101", "id": "reaction_10736457", "reactome": "R-SPO-197963", "name": "DHFR2 reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_197965" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10736454", "catalyst" ] ], "additional_components": [ "SPCC1223.08c" ] }, "reaction_10755856": { "compartment": "compartment_70101", "id": "reaction_10755856", "reactome": "R-SPO-8939959", "name": "NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869353" ], "products": [ "species_111294", "species_29360" ], "modifiers": [ [ "species_10736428", "catalyst" ] ], "additional_components": [ "Q9UT53", "SPAC806.06c", "species_29926" ] }, "reaction_10736889": { "compartment": "compartment_70101", "id": "reaction_10736889", "reactome": "R-SPO-200681", "name": "FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_200665" ], "products": [ "species_29370", "species_174404", "species_29372" ], "modifiers": [ [ "species_10736446", "catalyst" ] ], "additional_components": [ "SPBC1709.17" ] }, "reaction_10736421": { "compartment": "compartment_70101", "id": "reaction_10736421", "reactome": "R-SPO-197198", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29360" ], "products": [ "species_29370", "species_29366" ], "modifiers": [ [ "species_10736418", "catalyst" ] ], "additional_components": [ "species_442320", "O13863", "SPAC1B1.02c" ] }, "reaction_10755115": { "compartment": "compartment_70101", "id": "reaction_10755115", "reactome": "R-SPO-8869606", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10755112", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10736655": { "compartment": "compartment_70101", "id": "reaction_10736655", "reactome": "R-SPO-198824", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10736642" ], "products": [ "species_29360", "species_10736644" ], "modifiers": [ [ "species_10736652", "catalyst" ] ], "additional_components": [ "CHEBI:36144", "Q9USM6", "SPCC16A11.10c", "species_189444", "Q9USM6", "SPCC16A11.10c", "O74557", "SPCC970.03", "species_113596" ] }, "reaction_10736869": { "compartment": "compartment_70101", "id": "reaction_10736869", "reactome": "R-SPO-200661", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111353" ], "products": [ "species_200640", "species_29356" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10755480": { "compartment": "compartment_17927", "id": "reaction_10755480", "reactome": "R-SPO-8875838", "name": "SLC25A19 transports ThDP from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29480" ], "products": [ "species_8878387" ], "modifiers": [ [ "species_10755477", "catalyst" ] ], "additional_components": [ "SPBC1604.04" ] }, "reaction_10755123": { "compartment": "compartment_70101", "id": "reaction_10755123", "reactome": "R-SPO-8869627", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10755117", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10736459": { "compartment": "compartment_70101", "id": "reaction_10736459", "reactome": "R-SPO-197972", "name": "DHF is reduced to tetrahydrofolate (THF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_73604" ], "products": [ "species_29366", "species_111355" ], "modifiers": [ [ "species_10736454", "catalyst" ] ], "additional_components": [ "SPCC1223.08c" ] }, "reaction_10736879": { "compartment": "compartment_70101", "id": "reaction_10736879", "reactome": "R-SPO-200676", "name": "MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200739" ], "products": [ "species_29366", "species_174404" ], "modifiers": [ [ "species_10736876", "catalyst" ] ], "additional_components": [ "Q10258", "SPAC56F8.10" ] }, "reaction_10752948": { "compartment": "compartment_5460", "id": "reaction_10752948", "reactome": "R-SPO-6808487", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6808499", "species_113563", "species_113521" ], "products": [ "species_113600", "species_200679", "species_29376", "species_113529" ], "modifiers": [ [ "species_10752945", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10736666": { "compartment": "compartment_70616", "id": "reaction_10736666", "reactome": "R-SPO-199216", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194" ], "products": [ "species_29374" ], "modifiers": [ [ "species_10736663", "catalyst" ] ], "additional_components": [ "SPAC17H9.08" ] }, "reaction_10736327": { "compartment": "compartment_70101", "id": "reaction_10736327", "reactome": "R-SPO-194698", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644" ], "products": [ "species_29366", "species_194633" ], "modifiers": [ [ "species_10736324", "catalyst" ] ], "additional_components": [ "SPBC16G5.18" ] }, "reaction_10736094": { "compartment": "compartment_70101", "id": "reaction_10736094", "reactome": "R-SPO-191352", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191374" ], "products": [ "species_76194", "species_29366", "species_191424" ], "modifiers": [ [ "species_10736091", "catalyst" ] ], "additional_components": [ "Q10283", "SPCC162.09c" ] }, "reaction_10736314": { "compartment": "compartment_13231", "id": "reaction_10736314", "reactome": "R-SPO-194674", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194681", "species_194688", "species_194725" ], "products": [ "species_194704", "species_194668" ], "modifiers": [ [ "species_10736311", "catalyst" ] ], "additional_components": [ "SPBC16G5.18" ] }, "reaction_10736304": { "compartment": "compartment_70101", "id": "reaction_10736304", "reactome": "R-SPO-194642", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194735", "species_29360" ], "products": [ "species_70106", "species_73473", "species_113528", "species_194667" ], "modifiers": [ [ "species_10736301", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736084": { "compartment": "compartment_70101", "id": "reaction_10736084", "reactome": "R-SPO-191323", "name": "HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191293", "species_29356", "species_76183" ], "products": [ "species_70106", "species_76194", "species_191374" ], "modifiers": [ [ "species_10736081", "catalyst" ] ], "additional_components": [ "SPAC4F8.14c" ] }, "reaction_10736329": { "compartment": "compartment_70101", "id": "reaction_10736329", "reactome": "R-SPO-194718", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_194657" ], "products": [ "species_73473", "species_70106", "species_194661", "species_113528" ], "modifiers": [ [ "species_10736301", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736076": { "compartment": "compartment_70101", "id": "reaction_10736076", "reactome": "R-SPO-191303", "name": "FDPS dimer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191409" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10736073", "catalyst" ] ], "additional_components": [ "species_29926", "O14230", "SPAC6F12.13c" ] }, "reaction_10745569": { "compartment": "compartment_17957", "id": "reaction_10745569", "reactome": "R-SPO-5250531", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384" ], "products": [ "species_171095" ], "modifiers": [ [ "species_10745566", "catalyst" ] ], "additional_components": [ "SPAPB1A10.15" ] }, "reaction_10736079": { "compartment": "compartment_70101", "id": "reaction_10736079", "reactome": "R-SPO-191322", "name": "FDPS dimer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191324" ], "products": [ "species_191409", "species_111294" ], "modifiers": [ [ "species_10736073", "catalyst" ] ], "additional_components": [ "species_29926", "O14230", "SPAC6F12.13c" ] }, "reaction_10736306": { "compartment": "compartment_70101", "id": "reaction_10736306", "reactome": "R-SPO-194669", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194723", "species_29368" ], "products": [ "species_29366", "species_29356", "species_194657" ], "modifiers": [ [ "species_10736296", "catalyst" ] ], "additional_components": [ "SPAC630.08c" ] }, "reaction_10736102": { "compartment": "compartment_70101", "id": "reaction_10736102", "reactome": "R-SPO-191366", "name": "Squalene 2,3-epoxide cyclizes, forming lanosterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191309" ], "products": [ "species_194634" ], "modifiers": [ [ "species_10736099", "catalyst" ] ], "additional_components": [ "SPAC13G7.01c" ] }, "reaction_10736134": { "compartment": "compartment_70101", "id": "reaction_10736134", "reactome": "R-SPO-191405", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191385" ], "products": [ "species_191265", "species_111294" ], "modifiers": [ [ "species_10736129", "catalyst" ] ], "additional_components": [ "P36596", "SPBC646.05c", "species_29926" ] }, "reaction_10736112": { "compartment": "compartment_70101", "id": "reaction_10736112", "reactome": "R-SPO-191380", "name": "Mevalonate is phosphorylated to mevalonate-5-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191424" ], "products": [ "species_29370", "species_191296" ], "modifiers": [ [ "species_10736109", "catalyst" ] ], "additional_components": [ "Q09780", "SPAC13G6.11c" ] }, "reaction_10736122": { "compartment": "compartment_70101", "id": "reaction_10736122", "reactome": "R-SPO-191382", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362" ], "products": [ "species_191324" ], "modifiers": [ [ "species_10736119", "catalyst" ] ], "additional_components": [ "Q10132", "SPBC106.15", "species_29926" ] }, "reaction_10736299": { "compartment": "compartment_70101", "id": "reaction_10736299", "reactome": "R-SPO-194641", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644", "species_29368" ], "products": [ "species_29366", "species_194735", "species_29356" ], "modifiers": [ [ "species_10736296", "catalyst" ] ], "additional_components": [ "SPAC630.08c" ] }, "reaction_10736064": { "compartment": "compartment_70101", "id": "reaction_10736064", "reactome": "R-SPO-191299", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191269", "species_29368" ], "products": [ "species_29366", "species_191309", "species_29356" ], "modifiers": [ [ "species_10736061", "catalyst" ] ], "additional_components": [ "Q9C1W3", "SPBC713.12", "species_113596" ] }, "reaction_10736132": { "compartment": "compartment_70101", "id": "reaction_10736132", "reactome": "R-SPO-191402", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_191265", "species_29364" ], "products": [ "species_29366", "species_191269", "species_111294" ], "modifiers": [ [ "species_10736129", "catalyst" ] ], "additional_components": [ "P36596", "SPBC646.05c", "species_29926" ] }, "reaction_10735725": { "compartment": "compartment_7660", "id": "reaction_10735725", "reactome": "R-SPO-176318", "name": "Loading of claspin onto DNA during replication origin firing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735715", "species_10728877" ], "products": [ "species_10735717" ], "modifiers": [], "additional_components": [ "SPAC694.06c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9P7T4", "SPAC694.06c" ] }, "reaction_10735710": { "compartment": "compartment_7660", "id": "reaction_10735710", "reactome": "R-SPO-176264", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735705", "species_10735676" ], "products": [ "species_10735707" ], "modifiers": [ [ "species_10735676", "catalyst" ] ], "additional_components": [ "P26306", "SPAC664.07c", "P78955", "SPAC20G4.04c", "P22193", "SPAC1952.07", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13", "P26306", "SPAC664.07c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "P78955", "SPAC20G4.04c", "O14003", "SPAC27E2.10c", "P22193", "SPAC1952.07", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13" ] }, "reaction_10732950": { "compartment": "compartment_7660", "id": "reaction_10732950", "reactome": "R-SPO-75010", "name": "Phosphorylation of Cdc25C at Ser 216 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732945", "species_29358" ], "products": [ "species_113582", "species_10732948" ], "modifiers": [ [ "species_10729605", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "O13945", "SPAC23H4.02", "O74536", "SPCC74.03c" ] }, "reaction_10735678": { "compartment": "compartment_7660", "id": "reaction_10735678", "reactome": "R-SPO-176101", "name": "Recruitment of Rad17-RFC complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735674", "species_10735672" ], "products": [ "species_10735676" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "P50531", "SPAC14C4.13", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13" ] }, "reaction_10735686": { "compartment": "compartment_7660", "id": "reaction_10735686", "reactome": "R-SPO-176175", "name": "Stalling of DNA replication fork and RPA binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729504", "species_176104" ], "products": [ "species_10735674" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c" ] }, "reaction_10739846": { "compartment": "compartment_70101", "id": "reaction_10739846", "reactome": "R-SPO-450400", "name": "ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450597", "species_10739831", "species_10739842" ], "products": [ "species_10739844" ], "modifiers": [], "additional_components": [ "SPAC2F3.06c", "SPBC1718.07c", "P47979", "SPBC1718.07c", "O14089", "SPAC2F3.06c" ] }, "reaction_10744332": { "compartment": "compartment_70101", "id": "reaction_10744332", "reactome": "R-SPO-3371591", "name": "Trimerization of cytosolic HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744185" ], "products": [ "species_10744288" ], "modifiers": [ [ "species_10734704", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10" ] }, "reaction_10744290": { "compartment": "compartment_70101", "id": "reaction_10744290", "reactome": "R-SPO-3371527", "name": "HSF1 trimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744288" ], "products": [ "species_10744252" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10745134": { "compartment": "compartment_7660", "id": "reaction_10745134", "reactome": "R-SPO-5082409", "name": "Dissociation of HSF1:HSP90 complex in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745132" ], "products": [ "species_10745124", "species_10745130", "species_10745102" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "P41887", "SPAC926.04c", "Q02953", "SPAC2E12.02", "SPAC9E9.13", "P41887", "SPAC926.04c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10745615": { "compartment": "compartment_70101", "id": "reaction_10745615", "reactome": "R-SPO-5324632", "name": "Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745610", "species_5324631" ], "products": [ "species_10745612", "species_10744185", "species_10744270", "species_10737648" ], "modifiers": [ [ "species_10745610", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "Q9P3A7", "SPAC1565.08", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "P56523", "SPBC800.03", "Q9P3A7", "SPAC1565.08", "P56523", "SPBC800.03", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "SPAC9E9.13", "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "Q9P3A7", "SPAC1565.08", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "P56523", "SPBC800.03" ] }, "reaction_10745104": { "compartment": "compartment_7660", "id": "reaction_10745104", "reactome": "R-SPO-5082391", "name": "Trimerization of HSF1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745102" ], "products": [ "species_10744252" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10744324": { "compartment": "compartment_70101", "id": "reaction_10744324", "reactome": "R-SPO-3371586", "name": "Dissociation of cytosolic HSF1:HSP90 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744322" ], "products": [ "species_10744185", "species_10744270", "species_10737648" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "SPAC9E9.13" ] }, "reaction_10730060": { "compartment": "compartment_5460", "id": "reaction_10730060", "reactome": "R-SPO-70724", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_508190" ], "products": [ "species_113552", "species_508181" ], "modifiers": [ [ "species_10730057", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "O14370", "SPBC428.02c" ] }, "reaction_10730068": { "compartment": "compartment_5460", "id": "reaction_10730068", "reactome": "R-SPO-70881", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71847", "species_113521" ], "products": [ "species_29374", "species_573404" ], "modifiers": [ [ "species_10730065", "catalyst" ] ], "additional_components": [ "SPBC2D10.09" ] }, "reaction_10730052": { "compartment": "compartment_70101", "id": "reaction_10730052", "reactome": "R-SPO-70723", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_508182", "species_29406" ], "products": [ "species_29404", "species_508187" ], "modifiers": [ [ "species_10730049", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "O14370", "SPBC428.02c" ] }, "reaction_10756331": { "compartment": "compartment_5460", "id": "reaction_10756331", "reactome": "R-SPO-8952873", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_77343", "species_113529" ], "products": [ "species_113563", "species_77308" ], "modifiers": [ [ "species_10756328", "catalyst" ] ], "additional_components": [ "Q10488", "SPAC26F1.04c" ] }, "reaction_10744576": { "compartment": "compartment_7660", "id": "reaction_10744576", "reactome": "R-SPO-3782655", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10744514" ], "products": [ "species_5566518", "species_10744522" ], "modifiers": [ [ "species_10744573", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "SPBC800.03" ] }, "reaction_10744558": { "compartment": "compartment_7660", "id": "reaction_10744558", "reactome": "R-SPO-3769447", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10744514" ], "products": [ "species_5566518", "species_10744522" ], "modifiers": [ [ "species_10744553", "catalyst" ], [ "species_10744556", "inhibitor" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "O94405", "SPCC126.13c", "O74365", "SPBC30B4.04c", "LigandDisplayForward?ligandId=7489", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "LigandDisplayForward?ligandId=6852", "O94405", "SPCC126.13c", "LigandDisplayForward?ligandId=7496", "O74365", "SPBC30B4.04c" ] }, "reaction_10757824": { "compartment": "compartment_7660", "id": "reaction_10757824", "reactome": "R-SPO-9679787", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744553", "species_9679795" ], "products": [ "species_10744556" ], "modifiers": [], "additional_components": [ "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "O94405", "SPCC126.13c", "O74365", "SPBC30B4.04c", "LigandDisplayForward?ligandId=7489", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "LigandDisplayForward?ligandId=6852", "LigandDisplayForward?ligandId=7496", "LigandDisplayForward?ligandId=7489", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "LigandDisplayForward?ligandId=6852", "O94405", "SPCC126.13c", "LigandDisplayForward?ligandId=7496", "O74365", "SPBC30B4.04c" ] }, "reaction_10746196": { "compartment": "compartment_70101", "id": "reaction_10746196", "reactome": "R-SPO-5623667", "name": "PDPK1 phosphorylates PKN1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746165", "species_113592" ], "products": [ "species_29370", "species_10746193", "species_10738584", "species_10733718" ], "modifiers": [ [ "species_10746165", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "species_179838", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_179838", "Q12701", "SPCC576.15c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "species_179838", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c" ] }, "reaction_10746163": { "compartment": "compartment_876", "id": "reaction_10746163", "reactome": "R-SPO-5623622", "name": "RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746159", "species_10738584" ], "products": [ "species_10746161" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "P36582", "SPAC17G8.14c" ] }, "reaction_10746167": { "compartment": "compartment_876", "id": "reaction_10746167", "reactome": "R-SPO-5623632", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733718", "species_10746161" ], "products": [ "species_10746165" ], "modifiers": [], "additional_components": [ "species_179838", "Q12701", "SPCC576.15c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "species_179838", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c" ] }, "reaction_10746791": { "compartment": "compartment_70101", "id": "reaction_10746791", "reactome": "R-SPO-5671749", "name": "p-T774-PKN1 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746786" ], "products": [ "species_29370", "species_10746175", "species_10732952" ], "modifiers": [ [ "species_10746786", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P06652", "SPAC24H6.05", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "SPAC24H6.05", "P36583", "SPBC12D12.04c", "P06652", "SPAC24H6.05", "P36582", "SPAC17G8.14c" ] }, "reaction_10746788": { "compartment": "compartment_70101", "id": "reaction_10746788", "reactome": "R-SPO-5671737", "name": "p-T774-PKN1 binds CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746175", "species_10734625" ], "products": [ "species_10746786" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "SPAC24H6.05", "P36583", "SPBC12D12.04c", "P06652", "SPAC24H6.05", "P36582", "SPAC17G8.14c" ] }, "reaction_10756168": { "compartment": "compartment_70101", "id": "reaction_10756168", "reactome": "R-SPO-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749457" ], "products": [ "species_10749455", "species_10749446" ], "modifiers": [], "additional_components": [ "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c", "SPBC12D12.08c", "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c" ] }, "reaction_10756413": { "compartment": "compartment_70101", "id": "reaction_10756413", "reactome": "R-SPO-8955241", "name": "CAND1 binds cytosolic CRL E3 ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749492", "species_10756409" ], "products": [ "species_10756411" ], "modifiers": [], "additional_components": [ "SPAC1565.07c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9USX9", "SPBC1861.07", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "P10815", "SPBC582.03", "Q10311", "SPAC6C3.08", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "Q9UTL5", "SPAC144.09c", "Q9P3A8", "SPAC1565.07c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9USX9", "SPBC1861.07", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "P10815", "SPBC582.03", "Q10311", "SPAC6C3.08", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10749462": { "compartment": "compartment_70101", "id": "reaction_10749462", "reactome": "R-SPO-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749453", "species_29356" ], "products": [ "species_10749457", "species_10749459" ], "modifiers": [ [ "species_10749453", "catalyst" ] ], "additional_components": [ "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c", "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c", "SPBC12D12.08c", "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756192": { "compartment": "compartment_70101", "id": "reaction_10756192", "reactome": "R-SPO-8951656", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749455", "species_113592", "species_10756185" ], "products": [ "species_10756190", "species_111294", "species_76577" ], "modifiers": [], "additional_components": [ "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756321": { "compartment": "compartment_7660", "id": "reaction_10756321", "reactome": "R-SPO-8952638", "name": "AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756294" ], "products": [ "species_10756296", "species_10756318" ], "modifiers": [ [ "species_10756294", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "Q8WZK4", "SPBC839.03c", "SPCC777.10c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O14399", "SPBC12D12.08c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "Q8WZK4", "SPBC839.03c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "Q8WZK4", "SPBC839.03c" ] }, "reaction_10756214": { "compartment": "compartment_70101", "id": "reaction_10756214", "reactome": "R-SPO-8951751", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756195", "species_10756190" ], "products": [ "species_10756197" ], "modifiers": [], "additional_components": [ "SPCC777.10c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756208": { "compartment": "compartment_70101", "id": "reaction_10756208", "reactome": "R-SPO-8951661", "name": "Transfer of NEDD8 to AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756197" ], "products": [ "species_10756205", "species_10756185" ], "modifiers": [ [ "species_10756197", "catalyst" ] ], "additional_components": [ "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756250": { "compartment": "compartment_70101", "id": "reaction_10756250", "reactome": "R-SPO-8952618", "name": "AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756235" ], "products": [ "species_10756195", "species_10756247" ], "modifiers": [ [ "species_10756235", "catalyst" ] ], "additional_components": [ "O94289", "SPBC887.04c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O74531", "SPCC1827.08c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "O74549", "SPCC777.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O14399", "SPBC12D12.08c", "Q8WZK4", "SPBC839.03c", "SPCC777.10c", "O94289", "SPBC887.04c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O74531", "SPCC1827.08c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O14399", "SPBC12D12.08c", "Q8WZK4", "SPBC839.03c", "O94289", "SPBC887.04c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O74531", "SPCC1827.08c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "O74549", "SPCC777.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O14399", "SPBC12D12.08c", "Q8WZK4", "SPBC839.03c" ] }, "reaction_10756419": { "compartment": "compartment_7660", "id": "reaction_10756419", "reactome": "R-SPO-8955245", "name": "CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756415", "species_10756280" ], "products": [ "species_10756417" ], "modifiers": [], "additional_components": [ "SPAC1565.07c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "O13807", "SPAC17H9.10c", "Q9P3A8", "SPAC1565.07c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08" ] }, "reaction_10756188": { "compartment": "compartment_70101", "id": "reaction_10756188", "reactome": "R-SPO-8951648", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749455", "species_10756175", "species_113592" ], "products": [ "species_111294", "species_10756185", "species_76577" ], "modifiers": [ [ "species_10756175", "catalyst" ] ], "additional_components": [ "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c" ] }, "reaction_10754241": { "compartment": "compartment_70101", "id": "reaction_10754241", "reactome": "R-SPO-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754239" ], "products": [ "species_10729083", "species_10732101" ], "modifiers": [ [ "species_10754226", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09879", "SPCC188.08c", "Q10171", "SPAC27F1.03c" ] }, "reaction_10754194": { "compartment": "compartment_70101", "id": "reaction_10754194", "reactome": "R-SPO-8852134", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741355", "species_113592", "species_10729165" ], "products": [ "species_10754094", "species_111294" ], "modifiers": [ [ "species_10741355", "catalyst" ] ], "additional_components": [ "SPBC1604.21c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC1604.21c" ] }, "reaction_10754183": { "compartment": "compartment_7660", "id": "reaction_10754183", "reactome": "R-SPO-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754148", "species_10754162" ], "products": [ "species_10754181", "species_10753992" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P23566", "SPAC18B11.07c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH07", "SPAC1805.12c", "P23566", "SPAC18B11.07c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10753994": { "compartment": "compartment_7660", "id": "reaction_10753994", "reactome": "R-SPO-8852128", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10753862", "species_10729044" ], "products": [ "species_113541", "species_10753992" ], "modifiers": [], "additional_components": [ "SPBC1604.21c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754144": { "compartment": "compartment_70101", "id": "reaction_10754144", "reactome": "R-SPO-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753996", "species_10754092" ], "products": [ "species_10754094", "species_10754142" ], "modifiers": [], "additional_components": [ "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9Y818", "SPBC1105.09", "P0C8R3", "SPAC589.10c", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754254": { "compartment": "compartment_70101", "id": "reaction_10754254", "reactome": "R-SPO-8853515", "name": "OTULIN,USP5 cleaves UBC yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754251" ], "products": [ "species_10729083", "species_10729113", "species_10729093", "species_10729103", "species_10729163", "species_10729153", "species_10729143", "species_10729133", "species_10729123" ], "modifiers": [ [ "species_10748788", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC6B1.06c" ] }, "reaction_10754191": { "compartment": "compartment_70101", "id": "reaction_10754191", "reactome": "R-SPO-8852133", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754094" ], "products": [ "species_10753998", "species_76577" ], "modifiers": [ [ "species_10754094", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754188": { "compartment": "compartment_70101", "id": "reaction_10754188", "reactome": "R-SPO-8852132", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753998", "species_10729165" ], "products": [ "species_10754092", "species_111294" ], "modifiers": [ [ "species_10753998", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754196": { "compartment": "compartment_7660", "id": "reaction_10754196", "reactome": "R-SPO-8852136", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753992" ], "products": [ "species_10754146", "species_164121" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754185": { "compartment": "compartment_7660", "id": "reaction_10754185", "reactome": "R-SPO-8852131", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754146", "species_29358", "species_10729044" ], "products": [ "species_10754148", "species_113541" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754266": { "compartment": "compartment_70101", "id": "reaction_10754266", "reactome": "R-SPO-8853529", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754264" ], "products": [ "species_10729083", "species_10729093", "species_10729103" ], "modifiers": [ [ "species_10748788", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC6B1.06c" ] }, "reaction_10754229": { "compartment": "compartment_70101", "id": "reaction_10754229", "reactome": "R-SPO-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729083" ], "products": [ "species_10729083", "species_10731576" ], "modifiers": [ [ "species_10754226", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09879", "SPCC188.08c", "Q10171", "SPAC27F1.03c" ] }, "reaction_10732286": { "compartment": "compartment_70101", "id": "reaction_10732286", "reactome": "R-SPO-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_111627", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_29372", "species_111647" ], "modifiers": [ [ "species_10732277", "catalyst" ] ], "additional_components": [ "O94313", "SPBC215.08c", "Q09794", "SPAC22G7.06c" ] }, "reaction_10732266": { "compartment": "compartment_70101", "id": "reaction_10732266", "reactome": "R-SPO-73569", "name": "DHODH:FMN oxidises (S)-DHO to orotate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_76630" ], "products": [ "species_76633", "species_76632" ], "modifiers": [ [ "species_10732263", "catalyst" ] ], "additional_components": [ "species_73524", "P32747", "SPAC57A10.12c" ] }, "reaction_10732280": { "compartment": "compartment_70101", "id": "reaction_10732280", "reactome": "R-SPO-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111628" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10732277", "catalyst" ] ], "additional_components": [ "O94313", "SPBC215.08c", "Q09794", "SPAC22G7.06c" ] }, "reaction_10732283": { "compartment": "compartment_70101", "id": "reaction_10732283", "reactome": "R-SPO-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_111647" ], "products": [ "species_70106", "species_29372", "species_111628" ], "modifiers": [ [ "species_10732277", "catalyst" ] ], "additional_components": [ "O94313", "SPBC215.08c", "Q09794", "SPAC22G7.06c" ] }, "reaction_10746504": { "compartment": "compartment_7660", "id": "reaction_10746504", "reactome": "R-SPO-5653780", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746500", "species_10746496" ], "products": [ "species_10746502" ], "modifiers": [], "additional_components": [ "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "O60079", "SPCC1494.05c", "Q9USM5", "SPCC16A11.12c", "O60079", "SPCC1494.05c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "Q9USM5", "SPCC16A11.12c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c" ] }, "reaction_10746510": { "compartment": "compartment_7660", "id": "reaction_10746510", "reactome": "R-SPO-5653838", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746506", "species_10734037" ], "products": [ "species_10746508" ], "modifiers": [], "additional_components": [ "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "C6Y4D0", "SPCC16C4.22", "Q03392", "SPBC16D10.09" ] }, "reaction_10733936": { "compartment": "compartment_7660", "id": "reaction_10733936", "reactome": "R-SPO-110234", "name": "Cleavage of ethenocytosine by TDG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733933" ], "products": [ "species_10733889", "species_110233" ], "modifiers": [ [ "species_10733933", "catalyst" ] ], "additional_components": [ "O59825", "SPCC965.05c", "O59825", "SPCC965.05c", "O59825", "SPCC965.05c" ] }, "reaction_10734052": { "compartment": "compartment_7660", "id": "reaction_10734052", "reactome": "R-SPO-110368", "name": "POLD,POLE-mediated DNA strand displacement synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10734049" ], "products": [ "species_10734045", "species_113541" ], "modifiers": [ [ "species_10734049", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "P39750", "SPAC3G6.06c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "P39750", "SPAC3G6.06c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "P39750", "SPAC3G6.06c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10733885": { "compartment": "compartment_7660", "id": "reaction_10733885", "reactome": "R-SPO-110217", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733882" ], "products": [ "species_10733875", "species_110216" ], "modifiers": [ [ "species_10733882", "catalyst" ] ], "additional_components": [ "O74834", "SPCC1183.06", "O74834", "SPCC1183.06", "O74834", "SPCC1183.06" ] }, "reaction_10733892": { "compartment": "compartment_7660", "id": "reaction_10733892", "reactome": "R-SPO-110218", "name": "Cleavage of uracil by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733887" ], "products": [ "species_10733889", "species_29554" ], "modifiers": [ [ "species_10733887", "catalyst" ] ], "additional_components": [ "O59825", "SPCC965.05c", "O59825", "SPCC965.05c", "O59825", "SPCC965.05c" ] }, "reaction_10733899": { "compartment": "compartment_7660", "id": "reaction_10733899", "reactome": "R-SPO-110219", "name": "Cleavage of thymine by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733896" ], "products": [ "species_29692", "species_10733889" ], "modifiers": [ [ "species_10733896", "catalyst" ] ], "additional_components": [ "O59825", "SPCC965.05c", "O59825", "SPCC965.05c", "O59825", "SPCC965.05c" ] }, "reaction_10746388": { "compartment": "compartment_7660", "id": "reaction_10746388", "reactome": "R-SPO-5651805", "name": "LIG1 bound to APEX1 and PCNA ligates SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734058" ], "products": [ "species_10746385" ], "modifiers": [ [ "species_10734058", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01" ] }, "reaction_10733929": { "compartment": "compartment_7660", "id": "reaction_10733929", "reactome": "R-SPO-110229", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733926" ], "products": [ "species_5637659", "species_10733905" ], "modifiers": [ [ "species_10733926", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10733908": { "compartment": "compartment_7660", "id": "reaction_10733908", "reactome": "R-SPO-110224", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733903" ], "products": [ "species_110223", "species_10733905" ], "modifiers": [ [ "species_10733903", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10733915": { "compartment": "compartment_7660", "id": "reaction_10733915", "reactome": "R-SPO-110226", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733912" ], "products": [ "species_10733905", "species_110225" ], "modifiers": [ [ "species_10733912", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10733952": { "compartment": "compartment_7660", "id": "reaction_10733952", "reactome": "R-SPO-110246", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733947" ], "products": [ "species_10733949", "species_5635947" ], "modifiers": [ [ "species_10733947", "catalyst" ] ], "additional_components": [ "Q10159", "SPAC26A3.02", "Q10159", "SPAC26A3.02", "Q10159", "SPAC26A3.02" ] }, "reaction_10733878": { "compartment": "compartment_7660", "id": "reaction_10733878", "reactome": "R-SPO-110215", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733871" ], "products": [ "species_29554", "species_10733875" ], "modifiers": [ [ "species_10733871", "catalyst" ] ], "additional_components": [ "O74834", "SPCC1183.06", "O74834", "SPCC1183.06", "O74834", "SPCC1183.06" ] }, "reaction_10733922": { "compartment": "compartment_7660", "id": "reaction_10733922", "reactome": "R-SPO-110227", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733919" ], "products": [ "species_30140", "species_10733905" ], "modifiers": [ [ "species_10733919", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10734060": { "compartment": "compartment_7660", "id": "reaction_10734060", "reactome": "R-SPO-110371", "name": "LIG1 binds APEX1 and PCNA at SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729536", "species_10734056" ], "products": [ "species_10734058" ], "modifiers": [], "additional_components": [ "SPAC20G8.01", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01" ] }, "reaction_10735879": { "compartment": "compartment_984", "id": "reaction_10735879", "reactome": "R-SPO-189053", "name": "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189108", "species_109276" ], "products": [ "species_70115", "species_191103", "species_188986" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10736054": { "compartment": "compartment_984", "id": "reaction_10736054", "reactome": "R-SPO-191116", "name": "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191103", "species_109276" ], "products": [ "species_70115", "species_188986" ], "modifiers": [ [ "species_10735886", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c" ] }, "reaction_10736052": { "compartment": "compartment_984", "id": "reaction_10736052", "reactome": "R-SPO-191108", "name": "maltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188986", "species_109276" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10735882": { "compartment": "compartment_984", "id": "reaction_10735882", "reactome": "R-SPO-189069", "name": "sucrose + H2O => glucose + fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188980" ], "products": [ "species_70115", "species_189049" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10735889": { "compartment": "compartment_984", "id": "reaction_10735889", "reactome": "R-SPO-189102", "name": "maltose + H2O => 2 D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188986", "species_109276" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10735886", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c" ] }, "reaction_10746655": { "compartment": "compartment_984", "id": "reaction_10746655", "reactome": "R-SPO-5659861", "name": "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_5659875" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10736050": { "compartment": "compartment_984", "id": "reaction_10736050", "reactome": "R-SPO-191101", "name": "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191103", "species_109276" ], "products": [ "species_70115", "species_188986" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10728699": { "compartment": "compartment_7660", "id": "reaction_10728699", "reactome": "R-SPO-68611", "name": "Formation of ORC(1-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728693", "species_10728682" ], "products": [ "species_10728697" ], "modifiers": [], "additional_components": [ "P54789", "SPBC29A10.15", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15" ] }, "reaction_10758124": { "compartment": "compartment_7660", "id": "reaction_10758124", "reactome": "R-SPO-9757258", "name": "MCM2 binds MCM4:MCM6:MCM7 heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728828", "species_10728845" ], "products": [ "species_10728847" ], "modifiers": [], "additional_components": [ "SPBC4.04c", "P29458", "SPCC16A11.17", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "P29458", "SPCC16A11.17", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10758076": { "compartment": "compartment_7660", "id": "reaction_10758076", "reactome": "R-SPO-9749197", "name": "ORC1 binds to H4K20me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728689", "species_10758072" ], "products": [ "species_10758074" ], "modifiers": [], "additional_components": [ "SPBC29A10.15", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P54789", "SPBC29A10.15", "P04909", "SPCC622.08c" ] }, "reaction_10758120": { "compartment": "compartment_7660", "id": "reaction_10758120", "reactome": "R-SPO-9757256", "name": "MCM3 binds MCM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728857", "species_10728852" ], "products": [ "species_10728859" ], "modifiers": [], "additional_components": [ "SPAC1B2.05", "SPCC1682.02c", "P41389", "SPAC1B2.05", "P30666", "SPCC1682.02c" ] }, "reaction_10728666": { "compartment": "compartment_7660", "id": "reaction_10728666", "reactome": "R-SPO-68595", "name": "ORC2 binds ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728657", "species_10728662" ], "products": [ "species_10728664" ], "modifiers": [], "additional_components": [ "SPBC685.09", "SPAC3H1.01c", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09" ] }, "reaction_10758078": { "compartment": "compartment_7660", "id": "reaction_10758078", "reactome": "R-SPO-9749253", "name": "Formation of MCM2-7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728847", "species_10728859" ], "products": [ "species_10728861" ], "modifiers": [], "additional_components": [ "P29458", "SPCC16A11.17", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "P41389", "SPAC1B2.05", "P30666", "SPCC1682.02c", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10758051": { "compartment": "compartment_70101", "id": "reaction_10758051", "reactome": "R-SPO-9734713", "name": "ORC6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758033" ], "products": [ "species_10728705", "species_10758049" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12", "SPBC2A9.12", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c" ] }, "reaction_10758122": { "compartment": "compartment_7660", "id": "reaction_10758122", "reactome": "R-SPO-9757257", "name": "MCM4, MCM6 and MCM7 form a heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728843", "species_10728838", "species_10728833" ], "products": [ "species_10728845" ], "modifiers": [], "additional_components": [ "SPBC25D12.03c", "SPBC211.04c", "SPCC16A11.17", "P29458", "SPCC16A11.17", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10758029": { "compartment": "compartment_70101", "id": "reaction_10758029", "reactome": "R-SPO-9734670", "name": "ORC6 binds KPNA1 or KPNA6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758023", "species_10758025" ], "products": [ "species_10758027" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "SPBC2A9.12", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12" ] }, "reaction_10758055": { "compartment": "compartment_70101", "id": "reaction_10758055", "reactome": "R-SPO-9734730", "name": "ORC1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758053" ], "products": [ "species_10728689" ], "modifiers": [], "additional_components": [ "SPBC29A10.15", "SPBC29A10.15" ] }, "reaction_10728675": { "compartment": "compartment_7660", "id": "reaction_10728675", "reactome": "R-SPO-68603", "name": "ORC5 binds ORC2:ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728671", "species_10728664" ], "products": [ "species_10728673" ], "modifiers": [], "additional_components": [ "SPBC646.14c", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09" ] }, "reaction_10728684": { "compartment": "compartment_7660", "id": "reaction_10728684", "reactome": "R-SPO-68610", "name": "Formation of ORC(2-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728680", "species_10728673" ], "products": [ "species_10728682" ], "modifiers": [ [ "species_29358", "catalyst" ] ], "additional_components": [ "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09" ] }, "reaction_10728718": { "compartment": "compartment_7660", "id": "reaction_10728718", "reactome": "R-SPO-68688", "name": "CDC6 association with ORC(1-6) at replication origins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728714", "species_10728707" ], "products": [ "species_10728716" ], "modifiers": [], "additional_components": [ "SPBC14C8.07c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15", "O74796", "SPBC2A9.12", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P41411", "SPBC14C8.07c", "P54789", "SPBC29A10.15", "O74796", "SPBC2A9.12" ] }, "reaction_10758035": { "compartment": "compartment_70101", "id": "reaction_10758035", "reactome": "R-SPO-9734687", "name": "ORC6 is phosphorylated on T195", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758027", "species_113592" ], "products": [ "species_29370", "species_10758033" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12" ] }, "reaction_10728709": { "compartment": "compartment_7660", "id": "reaction_10728709", "reactome": "R-SPO-68615", "name": "Formation of ORC(1-6) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728705", "species_10728697" ], "products": [ "species_10728707" ], "modifiers": [], "additional_components": [ "SPBC2A9.12", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15", "O74796", "SPBC2A9.12" ] }, "reaction_10747495": { "compartment": "compartment_7660", "id": "reaction_10747495", "reactome": "R-SPO-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747490" ], "products": [ "species_113582", "species_10729617" ], "modifiers": [ [ "species_10747490", "catalyst" ] ], "additional_components": [ "Q10292", "SPAC14C4.03", "SPAC14C4.03", "Q10292", "SPAC14C4.03" ] }, "reaction_10747492": { "compartment": "compartment_7660", "id": "reaction_10747492", "reactome": "R-SPO-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747488" ], "products": [ "species_10747490" ], "modifiers": [], "additional_components": [ "SPAC14C4.03", "Q10292", "SPAC14C4.03" ] }, "reaction_10734987": { "compartment": "compartment_7660", "id": "reaction_10734987", "reactome": "R-SPO-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10733361" ], "modifiers": [], "additional_components": [ "SPAC1851.02" ] }, "reaction_10734985": { "compartment": "compartment_7660", "id": "reaction_10734985", "reactome": "R-SPO-163743", "name": "Transcriptional activation of Acetyl-CoA carboxylase by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10734983" ], "modifiers": [], "additional_components": [ "SPAC56E4.04c" ] }, "reaction_10734565": { "compartment": "compartment_70101", "id": "reaction_10734565", "reactome": "R-SPO-114684", "name": "Phosphorylation of Syntaxin-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734560" ], "products": [ "species_29370", "species_10734563" ], "modifiers": [ [ "species_10734542", "catalyst" ] ], "additional_components": [ "SPCC825.03c", "SPCC825.03c", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10734555": { "compartment": "compartment_70101", "id": "reaction_10734555", "reactome": "R-SPO-114683", "name": "Phosphorylation of Platelet Sec-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734549" ], "products": [ "species_29370", "species_10734552" ], "modifiers": [ [ "species_10734542", "catalyst" ] ], "additional_components": [ "SPCC584.05", "SPCC584.05", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10735552": { "compartment": "compartment_70101", "id": "reaction_10735552", "reactome": "R-SPO-174389", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174370", "species_113592" ], "products": [ "species_158471", "species_29370" ], "modifiers": [ [ "species_10735547", "catalyst" ] ], "additional_components": [ "SPAC1782.11" ] }, "reaction_10735571": { "compartment": "compartment_70101", "id": "reaction_10735571", "reactome": "R-SPO-174392", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174375", "species_113592" ], "products": [ "species_174370", "species_111294" ], "modifiers": [ [ "species_10735547", "catalyst" ] ], "additional_components": [ "SPAC1782.11" ] }, "reaction_10743381": { "compartment": "compartment_70101", "id": "reaction_10743381", "reactome": "R-SPO-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10743369" ], "products": [ "species_10743379", "species_29372" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13", "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13" ] }, "reaction_10743406": { "compartment": "compartment_70101", "id": "reaction_10743406", "reactome": "R-SPO-2529020", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743379", "species_113592" ], "products": [ "species_29370", "species_10743369" ], "modifiers": [ [ "species_10743403", "catalyst" ] ], "additional_components": [ "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13", "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11" ] }, "reaction_10733244": { "compartment": "compartment_7660", "id": "reaction_10733244", "reactome": "R-SPO-75172", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733240", "species_10733235" ], "products": [ "species_10733242" ], "modifiers": [], "additional_components": [ "SPAC13C5.07", "SPAC1556.01c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c" ] }, "reaction_10749600": { "compartment": "compartment_7660", "id": "reaction_10749600", "reactome": "R-SPO-5693540", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747252", "species_29358" ], "products": [ "species_10737781", "species_113582", "species_10749597" ], "modifiers": [ [ "species_10747252", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "SPCC23B6.03c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747255": { "compartment": "compartment_7660", "id": "reaction_10747255", "reactome": "R-SPO-5682044", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747250", "species_113560" ], "products": [ "species_2485002", "species_10747252" ], "modifiers": [ [ "species_10747250", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747567": { "compartment": "compartment_7660", "id": "reaction_10747567", "reactome": "R-SPO-5684006", "name": "KPNA2 translocates NBN to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747559" ], "products": [ "species_10747565", "species_10733249" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O43070", "SPBC6B1.09c", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "SPBC6B1.09c" ] }, "reaction_10733253": { "compartment": "compartment_7660", "id": "reaction_10733253", "reactome": "R-SPO-75174", "name": "Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733242", "species_10733249" ], "products": [ "species_10733251" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747569": { "compartment": "compartment_70101", "id": "reaction_10747569", "reactome": "R-SPO-5684008", "name": "NBN binds KPNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747555", "species_10747557" ], "products": [ "species_10747559" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "SPBC6B1.09c", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744580": { "compartment": "compartment_7660", "id": "reaction_10744580", "reactome": "R-SPO-3785768", "name": "MRN complex binds DNA double strand breaks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733251", "species_75165" ], "products": [ "species_10744578" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10749630": { "compartment": "compartment_7660", "id": "reaction_10749630", "reactome": "R-SPO-5693612", "name": "MRN complex bound to DNA ends recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747231", "species_10744578" ], "products": [ "species_10747250" ], "modifiers": [], "additional_components": [ "Q10325", "SPAC17G8.13c", "O74630", "SPCC23B6.03c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10730078": { "compartment": "compartment_5460", "id": "reaction_10730078", "reactome": "R-SPO-70938", "name": "lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113600", "species_29444", "species_113529" ], "products": [ "species_113563", "species_113521", "species_30176" ], "modifiers": [ [ "species_10730075", "catalyst" ] ], "additional_components": [ "O59711", "SPBC3B8.03" ] }, "reaction_10730211": { "compartment": "compartment_5460", "id": "reaction_10730211", "reactome": "R-SPO-71037", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_70951" ], "products": [ "species_70955", "species_29376", "species_29362" ], "modifiers": [ [ "species_10730208", "catalyst" ] ], "additional_components": [ "O94681", "SPBC776.15c", "species_29480", "O00087", "SPAC1002.09c", "CHEBI:17460", "O74378", "SPBC3H7.03c", "species_113596" ] }, "reaction_10730081": { "compartment": "compartment_5460", "id": "reaction_10730081", "reactome": "R-SPO-70940", "name": "saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_30176" ], "products": [ "species_113556", "species_113552", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730075", "catalyst" ] ], "additional_components": [ "O59711", "SPBC3B8.03" ] }, "reaction_10750324": { "compartment": "compartment_17951", "id": "reaction_10750324", "reactome": "R-SPO-6783880", "name": "PIPOX oxidises PPCA to P6C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693325", "species_113535" ], "products": [ "species_6783877", "species_113575" ], "modifiers": [ [ "species_10750321", "catalyst" ] ], "additional_components": [ "SPBC354.15" ] }, "reaction_10753848": { "compartment": "compartment_984", "id": "reaction_10753848", "reactome": "R-SPO-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851462", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851461" ], "modifiers": [ [ "species_10753845", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58280", "species_110094", "species_110096", "species_109395", "species_29602", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753831": { "compartment": "compartment_17963", "id": "reaction_10753831", "reactome": "R-SPO-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851227", "species_425969", "species_8851226" ], "modifiers": [ [ "species_10753828", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "species_110094", "species_110096", "species_109366", "species_109395", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c" ] }, "reaction_10753786": { "compartment": "compartment_876", "id": "reaction_10753786", "reactome": "R-SPO-8850854", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753780", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753824": { "compartment": "compartment_984", "id": "reaction_10753824", "reactome": "R-SPO-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753818", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753834": { "compartment": "compartment_17963", "id": "reaction_10753834", "reactome": "R-SPO-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851233", "species_2022884" ], "products": [ "species_425969", "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10753828", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "species_110094", "species_110096", "species_74016", "Q9USP2", "SPCC11E10.05c" ] }, "reaction_10753821": { "compartment": "compartment_984", "id": "reaction_10753821", "reactome": "R-SPO-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753818", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753855": { "compartment": "compartment_528865", "id": "reaction_10753855", "reactome": "R-SPO-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851509", "species_8851517" ], "products": [ "species_8851518", "species_8851513", "species_5228597" ], "modifiers": [ [ "species_10753852", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110614", "species_29420", "species_110096", "species_110094", "species_74016", "Q9USP2", "SPCC11E10.05c" ] }, "reaction_10753783": { "compartment": "compartment_984", "id": "reaction_10753783", "reactome": "R-SPO-8850846", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753780", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753857": { "compartment": "compartment_984", "id": "reaction_10753857", "reactome": "R-SPO-8851538", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726184", "species_109276" ], "products": [ "species_9726189", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753811", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753841": { "compartment": "compartment_984", "id": "reaction_10753841", "reactome": "R-SPO-8851356", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936165", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851369" ], "modifiers": [ [ "species_10753838", "catalyst" ] ], "additional_components": [ "species_29420", "species_29370", "species_110094", "species_110096", "species_109395", "species_76577", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753814": { "compartment": "compartment_984", "id": "reaction_10753814", "reactome": "R-SPO-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8936166" ], "products": [ "species_109277", "species_351626", "species_8851092" ], "modifiers": [ [ "species_10753811", "catalyst" ] ], "additional_components": [ "species_29494", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753860": { "compartment": "compartment_984", "id": "reaction_10753860", "reactome": "R-SPO-8851550", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726189", "species_109276" ], "products": [ "species_109277", "species_351626", "species_9726186" ], "modifiers": [ [ "species_10753811", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_109366", "species_109395", "species_29602", "species_76577", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10746363": { "compartment": "compartment_13949", "id": "reaction_10746363", "reactome": "R-SPO-5638014", "name": "RAB11A:GTP-containing Golgi vesicles recruit RAB3IP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746359", "species_10746347" ], "products": [ "species_10746361" ], "modifiers": [], "additional_components": [ "O13930", "SPAC23C4.10", "C6Y4C9", "SPCC1183.12", "P17610", "SPAC18G6.03", "species_29438", "P17610", "SPAC18G6.03", "O13930", "SPAC23C4.10", "C6Y4C9", "SPCC1183.12", "species_29438" ] }, "reaction_10756951": { "compartment": "compartment_70101", "id": "reaction_10756951", "reactome": "R-SPO-9018814", "name": "RHOT1 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756946", "species_29356" ], "products": [ "species_10756948", "species_29372" ], "modifiers": [ [ "species_10756946", "catalyst" ] ], "additional_components": [ "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "species_29420", "O59781", "SPCC320.04c", "species_29438" ] }, "reaction_10756961": { "compartment": "compartment_17906", "id": "reaction_10756961", "reactome": "R-SPO-9018815", "name": "RHOT1 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756957", "species_10756946" ], "products": [ "species_10756959" ], "modifiers": [], "additional_components": [ "O74805", "SPBC2D10.14c", "O94477", "SPCC1919.10c", "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "O74805", "SPBC2D10.14c", "species_29438", "O94477", "SPCC1919.10c" ] }, "reaction_10746671": { "compartment": "compartment_70101", "id": "reaction_10746671", "reactome": "R-SPO-5662471", "name": "SORD tetramer oxidizes xylitol to D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5660033", "species_29360" ], "products": [ "species_70106", "species_73473", "species_5661281" ], "modifiers": [ [ "species_10746446", "catalyst" ] ], "additional_components": [ "species_442320", "P36624", "SPBC1773.05c" ] }, "reaction_10746668": { "compartment": "compartment_70101", "id": "reaction_10746668", "reactome": "R-SPO-5662466", "name": "XYLB phosphorylates D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5661281", "species_113592" ], "products": [ "species_29370", "species_29790" ], "modifiers": [ [ "species_10746665", "catalyst" ] ], "additional_components": [ "SPCPJ732.02c" ] }, "reaction_10746139": { "compartment": "compartment_70101", "id": "reaction_10746139", "reactome": "R-SPO-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10746137" ], "products": [ "species_10746135", "species_29420" ], "modifiers": [ [ "species_10737885", "catalyst" ] ], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "P36579", "SPBC4F6.18c", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10745780": { "compartment": "compartment_7660", "id": "reaction_10745780", "reactome": "R-SPO-5358513", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358527", "species_10745776" ], "products": [ "species_10745778" ], "modifiers": [], "additional_components": [ "P26359", "SPAC8F11.03", "O74773", "SPBC19G7.01c", "species_29370", "P26359", "SPAC8F11.03", "O74773", "SPBC19G7.01c", "species_29370" ] }, "reaction_10750285": { "compartment": "compartment_7660", "id": "reaction_10750285", "reactome": "R-SPO-6782227", "name": "Ligation of newly synthesized repair patch to incised DNA in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750271" ], "products": [ "species_10749293", "species_10750283" ], "modifiers": [ [ "species_10729536", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "SPAC20G8.01" ] }, "reaction_10746607": { "compartment": "compartment_7660", "id": "reaction_10746607", "reactome": "R-SPO-5655835", "name": "POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746599", "species_10746603", "species_10733995", "species_10733957" ], "products": [ "species_10746605" ], "modifiers": [], "additional_components": [ "O74944", "SPCC553.07c", "species_113527", "species_29926", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "SPBC1347.01c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "Q0E7J8", "SPBC12D12.09", "P0C8R3", "SPAC589.10c", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746433": { "compartment": "compartment_7660", "id": "reaction_10746433", "reactome": "R-SPO-5652009", "name": "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746426", "species_10729044" ], "products": [ "species_10746430", "species_10734037", "species_10746424" ], "modifiers": [ [ "species_10746426", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "Q10990", "SPAC17H9.19c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "Q10990", "SPAC17H9.19c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "Q10990", "SPAC17H9.19c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10745785": { "compartment": "compartment_7660", "id": "reaction_10745785", "reactome": "R-SPO-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745767" ], "products": [ "species_10745782" ], "modifiers": [ [ "species_10745767", "catalyst" ] ], "additional_components": [ "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10749595": { "compartment": "compartment_7660", "id": "reaction_10749595", "reactome": "R-SPO-5693536", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10749592" ], "products": [ "species_113582", "species_10747437" ], "modifiers": [ [ "species_10749592", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10745797": { "compartment": "compartment_7660", "id": "reaction_10745797", "reactome": "R-SPO-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358610", "species_29358" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10729536", "catalyst" ] ], "additional_components": [ "SPAC20G8.01" ] }, "reaction_10747479": { "compartment": "compartment_7660", "id": "reaction_10747479", "reactome": "R-SPO-5683405", "name": "PPP5C dephosphorylates TP53BP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747469" ], "products": [ "species_113550", "species_10747471" ], "modifiers": [ [ "species_10747476", "catalyst" ] ], "additional_components": [ "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P87074", "SPBC342.05", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c", "SPBC3F6.01c" ] }, "reaction_10750503": { "compartment": "compartment_7660", "id": "reaction_10750503", "reactome": "R-SPO-6790454", "name": "SUMOylation of XPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749477", "species_10750487" ], "products": [ "species_10743639", "species_10750496" ], "modifiers": [ [ "species_10750500", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "Q9HDW3", "SPBC32F12.15", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O13351", "SPBC365.06", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O94451", "SPAC1687.05" ] }, "reaction_10733974": { "compartment": "compartment_7660", "id": "reaction_10733974", "reactome": "R-SPO-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733970", "species_10733957" ], "products": [ "species_10733972" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC1347.01c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746644": { "compartment": "compartment_7660", "id": "reaction_10746644", "reactome": "R-SPO-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10746635" ], "products": [ "species_10746641", "species_113541" ], "modifiers": [ [ "species_10746635", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749297": { "compartment": "compartment_7660", "id": "reaction_10749297", "reactome": "R-SPO-5690213", "name": "DNA polymerases delta, epsilon or kappa bind the GG-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749283", "species_10749285", "species_10749281", "species_10729448" ], "products": [ "species_10749295" ], "modifiers": [], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "O74944", "SPCC553.07c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P36617", "SPCC970.01", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P28706", "SPBC3E7.08c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "O74366", "SPBC30B4.07c" ] }, "reaction_10745941": { "compartment": "compartment_7660", "id": "reaction_10745941", "reactome": "R-SPO-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745744", "species_10745749" ], "products": [ "species_10745751" ], "modifiers": [], "additional_components": [ "SPBC1703.04", "SPAC19G12.02c", "P54280", "SPAC19G12.02c", "Q9P7W6", "SPBC1703.04" ] }, "reaction_10747451": { "compartment": "compartment_7660", "id": "reaction_10747451", "reactome": "R-SPO-5682983", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747446" ], "products": [ "species_113582", "species_10747439" ], "modifiers": [ [ "species_10747446", "catalyst" ] ], "additional_components": [ "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10747379": { "compartment": "compartment_7660", "id": "reaction_10747379", "reactome": "R-SPO-5682629", "name": "HERC2 facilitates UBE2N:UBE2V2 binding to RNF8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747364", "species_10747373" ], "products": [ "species_10747377" ], "modifiers": [], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c" ] }, "reaction_10745795": { "compartment": "compartment_7660", "id": "reaction_10745795", "reactome": "R-SPO-5358579", "name": "DNA polymerase delta polymerizes DNA across single stranded gap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_30187", "species_29604", "species_29892", "species_10745793" ], "products": [ "species_5358610", "species_10729504" ], "modifiers": [ [ "species_10729489", "catalyst" ] ], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04" ] }, "reaction_10749612": { "compartment": "compartment_7660", "id": "reaction_10749612", "reactome": "R-SPO-5693598", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749597", "species_29358" ], "products": [ "species_113582", "species_10747312" ], "modifiers": [ [ "species_10749597", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10745791": { "compartment": "compartment_7660", "id": "reaction_10745791", "reactome": "R-SPO-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358514", "species_10745787" ], "products": [ "species_10745789" ], "modifiers": [], "additional_components": [ "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c", "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c" ] }, "reaction_10746625": { "compartment": "compartment_7660", "id": "reaction_10746625", "reactome": "R-SPO-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746613", "species_30555" ], "products": [ "species_113541", "species_10733995", "species_10733957", "species_10746622" ], "modifiers": [ [ "species_10746613", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "SPBC1347.01c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746590": { "compartment": "compartment_7660", "id": "reaction_10746590", "reactome": "R-SPO-5655481", "name": "USP1:WDR48 binds monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746430", "species_10746581" ], "products": [ "species_10746583" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q09731", "SPAC31A2.14", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10749487": { "compartment": "compartment_7660", "id": "reaction_10749487", "reactome": "R-SPO-5691001", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10749464" ], "products": [ "species_10749484", "species_113541" ], "modifiers": [ [ "species_10749464", "catalyst" ] ], "additional_components": [ "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04" ] }, "reaction_10750274": { "compartment": "compartment_7660", "id": "reaction_10750274", "reactome": "R-SPO-6782208", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750269", "species_30555" ], "products": [ "species_113541", "species_10750271" ], "modifiers": [ [ "species_10750269", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c" ] }, "reaction_10745769": { "compartment": "compartment_7660", "id": "reaction_10745769", "reactome": "R-SPO-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729459", "species_10745751", "species_10745765" ], "products": [ "species_10745767" ], "modifiers": [], "additional_components": [ "Q03392", "SPBC16D10.09", "P54280", "SPAC19G12.02c", "Q9P7W6", "SPBC1703.04", "O74773", "SPBC19G7.01c", "species_113592", "O74502", "SPCC285.16c", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10745937": { "compartment": "compartment_7660", "id": "reaction_10745937", "reactome": "R-SPO-5444511", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10745756", "species_10745774" ], "products": [ "species_10745776" ], "modifiers": [], "additional_components": [ "SPBC19G7.01c", "SPAC8F11.03", "P26359", "SPAC8F11.03", "O74773", "SPBC19G7.01c", "species_29370" ] }, "reaction_10749480": { "compartment": "compartment_7660", "id": "reaction_10749480", "reactome": "R-SPO-5690996", "name": "ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10749473" ], "products": [ "species_113582", "species_113550", "species_10749477" ], "modifiers": [ [ "species_10749473", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O13807", "SPAC17H9.10c", "Q9HDW3", "SPBC32F12.15", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10747448": { "compartment": "compartment_7660", "id": "reaction_10747448", "reactome": "R-SPO-5682967", "name": "WHSC1 binds DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747437", "species_10747441" ], "products": [ "species_10747446" ], "modifiers": [], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "SPAC29B12.02c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10749607": { "compartment": "compartment_7660", "id": "reaction_10749607", "reactome": "R-SPO-5693566", "name": "TP53BP1 associates with H4K20Me2 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743694", "species_10747455" ], "products": [ "species_10747471" ], "modifiers": [], "additional_components": [ "SPBC342.05", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c" ] }, "reaction_10746597": { "compartment": "compartment_7660", "id": "reaction_10746597", "reactome": "R-SPO-5655483", "name": "USP1 autocleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746581" ], "products": [ "species_10746592", "species_10746579", "species_10746594" ], "modifiers": [ [ "species_10746581", "catalyst" ] ], "additional_components": [ "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "SPBC1703.12", "SPAC31A2.14", "SPBC1703.12", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10734004": { "compartment": "compartment_7660", "id": "reaction_10734004", "reactome": "R-SPO-110311", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10733997" ], "products": [ "species_10734001", "species_113541", "species_10733995" ], "modifiers": [ [ "species_10733997", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749469": { "compartment": "compartment_7660", "id": "reaction_10749469", "reactome": "R-SPO-5690990", "name": "5'- incision of DNA by ERCC1:ERCC4 in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749466" ], "products": [ "species_10749281" ], "modifiers": [ [ "species_10749466", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c" ] }, "reaction_10747367": { "compartment": "compartment_7660", "id": "reaction_10747367", "reactome": "R-SPO-5682607", "name": "PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747350", "species_10743647" ], "products": [ "species_10743639", "species_10747364" ], "modifiers": [ [ "species_10747350", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c" ] }, "reaction_10747463": { "compartment": "compartment_7660", "id": "reaction_10747463", "reactome": "R-SPO-5683077", "name": "RNF8 and RNF168 ubiquitinate KDM4A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747420", "species_10729044" ], "products": [ "species_10747458", "species_10747455" ], "modifiers": [ [ "species_10747420", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O94691", "SPBC83.07", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC83.07", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O94691", "SPBC83.07", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c" ] }, "reaction_10747353": { "compartment": "compartment_7660", "id": "reaction_10747353", "reactome": "R-SPO-5682598", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747346" ], "products": [ "species_113582", "species_10747350" ], "modifiers": [ [ "species_10747346", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c" ] }, "reaction_10747444": { "compartment": "compartment_7660", "id": "reaction_10747444", "reactome": "R-SPO-5682965", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747439", "species_77087" ], "products": [ "species_10747334", "species_77502" ], "modifiers": [ [ "species_10747439", "catalyst" ] ], "additional_components": [ "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10746428": { "compartment": "compartment_7660", "id": "reaction_10746428", "reactome": "R-SPO-5652005", "name": "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746424", "species_10746392" ], "products": [ "species_10746426" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "Q10990", "SPAC17H9.19c", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "Q10990", "SPAC17H9.19c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10747820": { "compartment": "compartment_7660", "id": "reaction_10747820", "reactome": "R-SPO-5689861", "name": "Recruitment of XPA and release of CAK ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747770", "species_10747816" ], "products": [ "species_10732457", "species_10747818" ], "modifiers": [], "additional_components": [ "SPBC649.03", "O13807", "SPAC17H9.10c", "P36613", "SPBP16F5.02", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74803", "SPBC2D10.12", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749628": { "compartment": "compartment_7660", "id": "reaction_10749628", "reactome": "R-SPO-5693602", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747312", "species_10747536" ], "products": [ "species_10749602" ], "modifiers": [], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10745811": { "compartment": "compartment_7660", "id": "reaction_10745811", "reactome": "R-SPO-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10745789" ], "products": [ "species_113582", "species_10745765" ], "modifiers": [], "additional_components": [ "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c", "O74773", "SPBC19G7.01c", "species_113592", "O74502", "SPCC285.16c" ] }, "reaction_10734026": { "compartment": "compartment_7660", "id": "reaction_10734026", "reactome": "R-SPO-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734015", "species_29604" ], "products": [ "species_113541", "species_10734023" ], "modifiers": [ [ "species_10734015", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10745939": { "compartment": "compartment_7660", "id": "reaction_10745939", "reactome": "R-SPO-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10745756", "species_10745761" ], "products": [ "species_10745787" ], "modifiers": [], "additional_components": [ "SPBC19G7.01c", "SPCC285.16c", "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c" ] }, "reaction_10747482": { "compartment": "compartment_7660", "id": "reaction_10747482", "reactome": "R-SPO-5683425", "name": "ATM phosphorylates TP53BP1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747471" ], "products": [ "species_113582", "species_10747469" ], "modifiers": [ [ "species_10747471", "catalyst" ] ], "additional_components": [ "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P87074", "SPBC342.05", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c" ] }, "reaction_10745806": { "compartment": "compartment_7660", "id": "reaction_10745806", "reactome": "R-SPO-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745782", "species_10745802" ], "products": [ "species_10745804" ], "modifiers": [], "additional_components": [ "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "SPBC29A10.05", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "P53695", "SPBC29A10.05" ] }, "reaction_10733831": { "compartment": "compartment_7660", "id": "reaction_10733831", "reactome": "R-SPO-109955", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733822", "species_10733827" ], "products": [ "species_10733829" ], "modifiers": [], "additional_components": [ "SPBC4F6.15c", "SPCC970.01", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c" ] }, "reaction_10734035": { "compartment": "compartment_7660", "id": "reaction_10734035", "reactome": "R-SPO-110322", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733993", "species_10733988" ], "products": [ "species_10733995" ], "modifiers": [], "additional_components": [ "SPBC12D12.09", "SPAC688.10", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10" ] }, "reaction_10745809": { "compartment": "compartment_7660", "id": "reaction_10745809", "reactome": "R-SPO-5358599", "name": "EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745804", "species_10729504" ], "products": [ "species_10745793" ], "modifiers": [ [ "species_10745804", "catalyst" ] ], "additional_components": [ "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "P53695", "SPBC29A10.05", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "P53695", "SPBC29A10.05" ] }, "reaction_10746435": { "compartment": "compartment_7660", "id": "reaction_10746435", "reactome": "R-SPO-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733995", "species_10733980" ], "products": [ "species_10733997" ], "modifiers": [], "additional_components": [ "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746653": { "compartment": "compartment_7660", "id": "reaction_10746653", "reactome": "R-SPO-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746641", "species_30555" ], "products": [ "species_10746650", "species_113541", "species_10733957", "species_10733995" ], "modifiers": [ [ "species_10746641", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC1347.01c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10734017": { "compartment": "compartment_7660", "id": "reaction_10734017", "reactome": "R-SPO-110316", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734013", "species_10734009" ], "products": [ "species_10734015" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC16A3.11", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746588": { "compartment": "compartment_7660", "id": "reaction_10746588", "reactome": "R-SPO-5655466", "name": "USP1:WDR48 deubiquitinates monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746583" ], "products": [ "species_10746581", "species_10729044", "species_10746585" ], "modifiers": [ [ "species_10746583", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q09731", "SPAC31A2.14", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9P7V9", "SPBC1703.12", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q09731", "SPAC31A2.14", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10746564": { "compartment": "compartment_7660", "id": "reaction_10746564", "reactome": "R-SPO-5654985", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746544", "species_10746560" ], "products": [ "species_10746562" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O42915", "SPBC16A3.09c", "Q9P3A7", "SPAC1565.08", "Q9P780", "SPBC1711.10c", "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10733983": { "compartment": "compartment_7660", "id": "reaction_10733983", "reactome": "R-SPO-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10733972" ], "products": [ "species_10733980" ], "modifiers": [ [ "species_10733972", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749609": { "compartment": "compartment_7660", "id": "reaction_10749609", "reactome": "R-SPO-5693583", "name": "MDC1 associates with gamma-H2AFX at nuclear foci", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747435", "species_10749590" ], "products": [ "species_10749592" ], "modifiers": [], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14079", "SPACUNK4.14", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10749471": { "compartment": "compartment_7660", "id": "reaction_10749471", "reactome": "R-SPO-5690991", "name": "Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747788", "species_10733829" ], "products": [ "species_10749466" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c" ] }, "reaction_10747423": { "compartment": "compartment_7660", "id": "reaction_10747423", "reactome": "R-SPO-5682858", "name": "RNF8 and RNF168 ubiquitinate H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747398", "species_10729044" ], "products": [ "species_10747420" ], "modifiers": [ [ "species_10747398", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O94691", "SPBC83.07", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c" ] }, "reaction_10746616": { "compartment": "compartment_7660", "id": "reaction_10746616", "reactome": "R-SPO-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746605", "species_30555" ], "products": [ "species_10746613", "species_113541" ], "modifiers": [ [ "species_10746605", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "Q0E7J8", "SPBC12D12.09", "P0C8R3", "SPAC589.10c", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "Q0E7J8", "SPBC12D12.09", "P0C8R3", "SPAC589.10c", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749977": { "compartment": "compartment_7660", "id": "reaction_10749977", "reactome": "R-SPO-5696465", "name": "USP45 deubiquitinates ERCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10749972" ], "products": [ "species_10733822", "species_10729044" ], "modifiers": [ [ "species_10749974", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q06182", "SPBC4F6.15c", "SPBC4F6.15c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPAC23G3.08c" ] }, "reaction_10734033": { "compartment": "compartment_7660", "id": "reaction_10734033", "reactome": "R-SPO-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10734023" ], "products": [ "species_10734030", "species_113541" ], "modifiers": [ [ "species_10734023", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746569": { "compartment": "compartment_7660", "id": "reaction_10746569", "reactome": "R-SPO-5654989", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746562", "species_29358" ], "products": [ "species_113582", "species_10746566", "species_10734009" ], "modifiers": [ [ "species_10746562", "catalyst" ] ], "additional_components": [ "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC16A3.11", "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10747453": { "compartment": "compartment_7660", "id": "reaction_10747453", "reactome": "R-SPO-5682992", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747336", "species_10747334" ], "products": [ "species_10747340" ], "modifiers": [], "additional_components": [ "SPBC83.07", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10747790": { "compartment": "compartment_7660", "id": "reaction_10747790", "reactome": "R-SPO-5689317", "name": "Formation of the pre-incision complex in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747786", "species_10747765", "species_10729504" ], "products": [ "species_10747788" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13768", "SPAC17A5.06", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P26659", "SPAC1D4.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "O74995", "SPCC1682.07", "SPBC3E7.08c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c" ] }, "reaction_10749605": { "compartment": "compartment_7660", "id": "reaction_10749605", "reactome": "R-SPO-5693549", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10749602" ], "products": [ "species_113582", "species_10747546" ], "modifiers": [ [ "species_10749602", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10743005": { "compartment": "compartment_5460", "id": "reaction_10743005", "reactome": "R-SPO-2162253", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162256", "species_2162257" ], "products": [ "species_2162214", "species_159450" ], "modifiers": [ [ "species_10743002", "catalyst" ] ], "additional_components": [ "O13851", "SPAC19G12.12", "species_29926", "O43091", "SPBPJ4664.01" ] }, "reaction_10742984": { "compartment": "compartment_5460", "id": "reaction_10742984", "reactome": "R-SPO-2162193", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162209", "species_2162265" ], "products": [ "species_2162252", "species_2162215", "species_113529" ], "modifiers": [ [ "species_10742970", "catalyst" ] ], "additional_components": [ "SPCC162.05" ] }, "reaction_10742973": { "compartment": "compartment_5460", "id": "reaction_10742973", "reactome": "R-SPO-2162186", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162212", "species_2162265" ], "products": [ "species_2162252", "species_2162198", "species_113529" ], "modifiers": [ [ "species_10742970", "catalyst" ] ], "additional_components": [ "SPCC162.05" ] }, "reaction_10742981": { "compartment": "compartment_70616", "id": "reaction_10742981", "reactome": "R-SPO-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10742978", "catalyst" ] ], "additional_components": [ "SPBC3F6.01c" ] }, "reaction_10734456": { "compartment": "compartment_7660", "id": "reaction_10734456", "reactome": "R-SPO-112430", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734280", "species_10734258" ], "products": [ "species_10734282" ], "modifiers": [], "additional_components": [ "O74627", "SPBC32F12.06", "O59748", "SPBC530.13", "SPAC2F3.15", "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15", "O59748", "SPBC530.13" ] }, "reaction_10734442": { "compartment": "compartment_7660", "id": "reaction_10734442", "reactome": "R-SPO-112392", "name": "Resumption of elongation after recovery from pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734440" ], "products": [ "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734458": { "compartment": "compartment_7660", "id": "reaction_10734458", "reactome": "R-SPO-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733600", "species_10734297" ], "products": [ "species_10734299" ], "modifiers": [], "additional_components": [ "SPAC23C4.19", "SPBC21C3.16c", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19" ] }, "reaction_10733342": { "compartment": "compartment_7660", "id": "reaction_10733342", "reactome": "R-SPO-75862", "name": "Fall Back to Closed Pre-initiation Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733332" ], "products": [ "species_10733340" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10734468": { "compartment": "compartment_7660", "id": "reaction_10734468", "reactome": "R-SPO-113413", "name": "TFIIS-mediated recovery of elongation from arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734454": { "compartment": "compartment_7660", "id": "reaction_10734454", "reactome": "R-SPO-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734357", "species_10734352" ], "products": [ "species_10734359" ], "modifiers": [], "additional_components": [ "SPBP8B7.19", "SPBC609.05", "O94529", "SPBC609.05", "O94267", "SPBP8B7.19" ] }, "reaction_10734462": { "compartment": "compartment_7660", "id": "reaction_10734462", "reactome": "R-SPO-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734367" ], "products": [ "species_10734367" ], "modifiers": [], "additional_components": [ "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13936", "SPAC23C4.19", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13936", "SPAC23C4.19", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10732715": { "compartment": "compartment_7660", "id": "reaction_10732715", "reactome": "R-SPO-73946", "name": "Abortive initiation after formation of the first phosphodiester bond", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732713" ], "products": [ "species_109877", "species_10732699", "species_10732619", "species_10732494", "species_10732624", "species_10732711", "species_10730708" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "SPAC16E8.16", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10733330": { "compartment": "compartment_7660", "id": "reaction_10733330", "reactome": "R-SPO-75856", "name": "Abortive Initiation Before Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733328" ], "products": [ "species_110068", "species_10732699", "species_10732619", "species_10732494", "species_10732624", "species_10732711", "species_10730708" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "SPAC16E8.16", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10734446": { "compartment": "compartment_7660", "id": "reaction_10734446", "reactome": "R-SPO-112395", "name": "Abortive termination of elongation after arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734444" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734464": { "compartment": "compartment_7660", "id": "reaction_10734464", "reactome": "R-SPO-113411", "name": "2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734440" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734470": { "compartment": "compartment_7660", "id": "reaction_10734470", "reactome": "R-SPO-113414", "name": "7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10733400": { "compartment": "compartment_7660", "id": "reaction_10733400", "reactome": "R-SPO-75891", "name": "Abortive Initiation After Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733398" ], "products": [ "species_75897", "species_10732494", "species_10732711", "species_10730708" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10737527": { "compartment": "compartment_70101", "id": "reaction_10737527", "reactome": "R-SPO-209792", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183", "species_209914" ], "products": [ "species_76194", "species_209793" ], "modifiers": [ [ "species_10737524", "catalyst" ] ], "additional_components": [ "SPAC9.02c" ] }, "reaction_10741986": { "compartment": "compartment_12045", "id": "reaction_10741986", "reactome": "R-SPO-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741994": { "compartment": "compartment_12045", "id": "reaction_10741994", "reactome": "R-SPO-1482827", "name": "PC is hydrolyzed to 2-acyl LPC by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742013": { "compartment": "compartment_12045", "id": "reaction_10742013", "reactome": "R-SPO-1482862", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741810": { "compartment": "compartment_12045", "id": "reaction_10741810", "reactome": "R-SPO-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741770": { "compartment": "compartment_12045", "id": "reaction_10741770", "reactome": "R-SPO-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10742007": { "compartment": "compartment_12045", "id": "reaction_10742007", "reactome": "R-SPO-1482856", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10742004", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10738121": { "compartment": "compartment_5460", "id": "reaction_10738121", "reactome": "R-SPO-380608", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380598", "species_113526" ], "products": [ "species_380593", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730539", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10742179": { "compartment": "compartment_70101", "id": "reaction_10742179", "reactome": "R-SPO-1497796", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737053", "species_1497857" ], "products": [ "species_29870", "species_10742177" ], "modifiers": [], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "P36587", "SPBC29A10.01", "species_29870", "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_1497857", "species_29870", "P36587", "SPBC29A10.01" ] }, "reaction_10741760": { "compartment": "compartment_70101", "id": "reaction_10741760", "reactome": "R-SPO-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10741757", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ] ], "additional_components": [ "O13774", "SPAC17A5.13" ] }, "reaction_10735967": { "compartment": "compartment_5460", "id": "reaction_10735967", "reactome": "R-SPO-189465", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189487", "species_113531" ], "products": [ "species_189444", "species_113529" ], "modifiers": [ [ "species_10735964", "catalyst" ], [ "species_391232", "inhibitor" ] ], "additional_components": [ "O59786", "SPCC320.09" ] }, "reaction_10735899": { "compartment": "compartment_70101", "id": "reaction_10735899", "reactome": "R-SPO-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189464", "species_29356" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10735896", "catalyst" ] ], "additional_components": [ "CHEBI:36319", "Q09899", "SPAC24B11.13" ] }, "reaction_10747163": { "compartment": "compartment_70101", "id": "reaction_10747163", "reactome": "R-SPO-5679041", "name": "ABCC2 transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5679042", "species_29356" ], "products": [ "species_29370", "species_5679034", "species_29372" ], "modifiers": [ [ "species_10741710", "catalyst" ] ], "additional_components": [ "CHEBI:16427", "CHEBI:18392", "CHEBI:16427", "CHEBI:18392", "Q10185", "SPAC3F10.11c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10735981": { "compartment": "compartment_70101", "id": "reaction_10735981", "reactome": "R-SPO-190182", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190157" ], "products": [ "species_113528", "species_190128" ], "modifiers": [ [ "species_10735926", "catalyst" ] ], "additional_components": [ "Q9USJ5", "SPCC4B3.05c" ] }, "reaction_10735909": { "compartment": "compartment_17927", "id": "reaction_10735909", "reactome": "R-SPO-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189411", "species_189461" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10735906", "catalyst" ] ], "additional_components": [ "Q9UTE2", "SPAC222.11" ] }, "reaction_10735939": { "compartment": "compartment_70101", "id": "reaction_10735939", "reactome": "R-SPO-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_70106", "species_189464", "species_29356" ], "modifiers": [ [ "species_10735936", "catalyst" ] ], "additional_components": [ "P78974", "SPAC1805.06c", "species_442320" ] }, "reaction_10735975": { "compartment": "compartment_70101", "id": "reaction_10735975", "reactome": "R-SPO-189488", "name": "UROS transforms HMB to URO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189449" ], "products": [ "species_189407", "species_29356" ], "modifiers": [ [ "species_10735972", "catalyst" ] ], "additional_components": [ "SPAC31G5.08" ] }, "reaction_10735929": { "compartment": "compartment_70101", "id": "reaction_10735929", "reactome": "R-SPO-189425", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189407" ], "products": [ "species_113528", "species_189455" ], "modifiers": [ [ "species_10735926", "catalyst" ] ], "additional_components": [ "Q9USJ5", "SPCC4B3.05c" ] }, "reaction_10743681": { "compartment": "compartment_5460", "id": "reaction_10743681", "reactome": "R-SPO-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_2162257", "species_189444" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10743678", "catalyst" ] ], "additional_components": [ "SPBC365.02c" ] }, "reaction_10735957": { "compartment": "compartment_5460", "id": "reaction_10735957", "reactome": "R-SPO-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_159549", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10735954", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "O14092", "SPAC2F3.09" ] }, "reaction_10735979": { "compartment": "compartment_70101", "id": "reaction_10735979", "reactome": "R-SPO-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735936", "species_190173" ], "products": [ "species_29426", "species_10735977" ], "modifiers": [], "additional_components": [ "P78974", "SPAC1805.06c", "species_442320", "P78974", "SPAC1805.06c", "species_442320", "species_190173" ] }, "reaction_10735919": { "compartment": "compartment_17927", "id": "reaction_10735919", "reactome": "R-SPO-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10735916", "catalyst" ] ], "additional_components": [ "Q10062", "SPAC1F5.07c", "species_113596" ] }, "reaction_10757699": { "compartment": "compartment_70101", "id": "reaction_10757699", "reactome": "R-SPO-9661405", "name": "ABCC1 transports BIL from cytosol to extracellular region (blood)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189386" ], "products": [ "species_9661418" ], "modifiers": [ [ "species_10737726", "catalyst" ] ], "additional_components": [ "SPAC3F10.11c" ] }, "reaction_10743689": { "compartment": "compartment_5460", "id": "reaction_10743689", "reactome": "R-SPO-2995334", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2995328" ], "products": [ "species_2995348" ], "modifiers": [ [ "species_10743686", "catalyst" ] ], "additional_components": [ "SPAC22E12.10c" ] }, "reaction_10757253": { "compartment": "compartment_17947", "id": "reaction_10757253", "reactome": "R-SPO-9603784", "name": "PEX19:class I PMP binds PEX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757231", "species_10738205" ], "products": [ "species_10757233" ], "modifiers": [], "additional_components": [ "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14136", "SPAC3C7.10", "SPAC29A4.14c", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14017", "SPAC29A4.14c", "O14136", "SPAC3C7.10" ] }, "reaction_10757255": { "compartment": "compartment_70101", "id": "reaction_10757255", "reactome": "R-SPO-9603804", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757189", "species_10757229" ], "products": [ "species_10757231" ], "modifiers": [], "additional_components": [ "SPAC17C9.14", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "O14136", "SPAC3C7.10", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14136", "SPAC3C7.10" ] }, "reaction_10757251": { "compartment": "compartment_17947", "id": "reaction_10757251", "reactome": "R-SPO-9603775", "name": "PEX3:PEX19:class I PMP dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757233" ], "products": [ "species_10757189", "species_10757249", "species_10738205" ], "modifiers": [], "additional_components": [ "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14017", "SPAC29A4.14c", "O14136", "SPAC3C7.10", "SPAC17C9.14", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "O14136", "SPAC3C7.10", "SPAC29A4.14c" ] }, "reaction_10738119": { "compartment": "compartment_374932", "id": "reaction_10738119", "reactome": "R-SPO-380586", "name": "loading of Serotonin in synaptic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209914" ], "products": [ "species_380585" ], "modifiers": [ [ "species_10737993", "catalyst" ] ], "additional_components": [ "SPCC18.02" ] }, "reaction_10757333": { "compartment": "compartment_70101", "id": "reaction_10757333", "reactome": "R-SPO-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737034", "species_10757329" ], "products": [ "species_10757331" ], "modifiers": [], "additional_components": [ "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "SPACUNK12.02c", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9P7I2", "SPACUNK12.02c" ] }, "reaction_10757822": { "compartment": "compartment_876", "id": "reaction_10757822", "reactome": "R-SPO-9679775", "name": "COMT binds COMT Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9679778", "species_10738036" ], "products": [ "species_10738039" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=6646", "LigandDisplayForward?ligandId=6647", "LigandDisplayForward?ligandId=8988", "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6646", "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6647", "LigandDisplayForward?ligandId=8988" ] }, "reaction_10738044": { "compartment": "compartment_70101", "id": "reaction_10738044", "reactome": "R-SPO-379464", "name": "COMT transfers Met to DOPAC to form HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9677997", "species_71284" ], "products": [ "species_174369", "species_9677992" ], "modifiers": [ [ "species_10738036", "catalyst" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c" ] }, "reaction_10738041": { "compartment": "compartment_70101", "id": "reaction_10738041", "reactome": "R-SPO-379387", "name": "COMT transfers Met to DA to form 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159362", "species_71284" ], "products": [ "species_71285", "species_8954997" ], "modifiers": [ [ "species_10738036", "catalyst" ], [ "species_10738039", "inhibitor" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6646", "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6647", "LigandDisplayForward?ligandId=8988" ] }, "reaction_10737996": { "compartment": "compartment_374932", "id": "reaction_10737996", "reactome": "R-SPO-372542", "name": "Loading of dopamine into synaptic veiscles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159362" ], "products": [ "species_351601" ], "modifiers": [ [ "species_10737993", "catalyst" ] ], "additional_components": [ "SPCC18.02" ] }, "reaction_10757324": { "compartment": "compartment_70101", "id": "reaction_10757324", "reactome": "R-SPO-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10757317" ], "products": [ "species_29370", "species_10757321" ], "modifiers": [ [ "species_10757317", "catalyst" ] ], "additional_components": [ "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05" ] }, "reaction_10756407": { "compartment": "compartment_70101", "id": "reaction_10756407", "reactome": "R-SPO-8955010", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159362", "species_71284" ], "products": [ "species_71285", "species_8954997" ], "modifiers": [ [ "species_10756404", "catalyst" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c" ] }, "reaction_10757358": { "compartment": "compartment_876", "id": "reaction_10757358", "reactome": "R-SPO-9625814", "name": "SPHK1 phosphorylates sphingosine in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1606609" ], "products": [ "species_5218688" ], "modifiers": [ [ "species_10738404", "catalyst" ] ], "additional_components": [ "SPAC4A8.07c" ] }, "reaction_10737078": { "compartment": "compartment_20699", "id": "reaction_10737078", "reactome": "R-SPO-202132", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737066" ], "products": [ "species_10737076" ], "modifiers": [], "additional_components": [ "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_29870", "species_113596", "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_29870", "species_113596" ] }, "reaction_10737226": { "compartment": "compartment_20699", "id": "reaction_10737226", "reactome": "R-SPO-203700", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737196" ], "products": [ "species_10736995" ], "modifiers": [], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_113596" ] }, "reaction_10737204": { "compartment": "compartment_20699", "id": "reaction_10737204", "reactome": "R-SPO-203567", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737064", "species_200993" ], "products": [ "species_10737196" ], "modifiers": [ [ "species_10737201", "catalyst" ] ], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "SPBC3H7.09" ] }, "reaction_10737214": { "compartment": "compartment_70101", "id": "reaction_10737214", "reactome": "R-SPO-203611", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737212", "species_184174" ], "products": [ "species_10737064" ], "modifiers": [], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01" ] }, "reaction_10737224": { "compartment": "compartment_876", "id": "reaction_10737224", "reactome": "R-SPO-203613", "name": "depalmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736995" ], "products": [ "species_76168", "species_10737066" ], "modifiers": [ [ "species_10737221", "catalyst" ] ], "additional_components": [ "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_113596", "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_29870", "species_113596", "O42881", "SPAC8E11.04c" ] }, "reaction_10742182": { "compartment": "compartment_70101", "id": "reaction_10742182", "reactome": "R-SPO-1497810", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29368" ], "products": [ "species_29366", "species_1222424" ], "modifiers": [ [ "species_10742177", "catalyst" ] ], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_1497857", "species_29870", "P36587", "SPBC29A10.01" ] }, "reaction_10740054": { "compartment": "compartment_876", "id": "reaction_10740054", "reactome": "R-SPO-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740042" ], "products": [ "species_10740052" ], "modifiers": [], "additional_components": [ "O74557", "SPCC970.03", "O13809", "SPAC17H9.12c", "P87178", "SPBC3D6.13c", "O74557", "SPCC970.03", "O13809", "SPAC17H9.12c", "P87178", "SPBC3D6.13c" ] }, "reaction_10734544": { "compartment": "compartment_70101", "id": "reaction_10734544", "reactome": "R-SPO-114553", "name": "Activation of conventional Protein Kinase C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734522", "species_74016", "species_33625", "species_114519" ], "products": [ "species_10734542" ], "modifiers": [ [ "species_114519", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10740115": { "compartment": "compartment_70101", "id": "reaction_10740115", "reactome": "R-SPO-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740085" ], "products": [ "species_10740113" ], "modifiers": [], "additional_components": [ "O94590", "SPCC584.05", "P28758", "SPAC821.10c", "P04689", "SPBC800.05c", "P05933", "SPAC3A12.14", "O60054", "SPBC56F2.03", "O14008", "SPAC29A4.05", "P04688", "SPBC16A3.15c", "P10989", "SPBC32H8.12c", "O42914", "SPBC16A3.08c", "O14301", "SPAC9G1.05", "O94590", "SPCC584.05", "P28758", "SPAC821.10c", "P04689", "SPBC800.05c", "P05933", "SPAC3A12.14", "O60054", "SPBC56F2.03", "O14008", "SPAC29A4.05", "P04688", "SPBC16A3.15c", "P10989", "SPBC32H8.12c", "O42914", "SPBC16A3.08c", "O14301", "SPAC9G1.05" ] }, "reaction_10740026": { "compartment": "compartment_876", "id": "reaction_10740026", "reactome": "R-SPO-481009", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740020" ], "products": [ "species_10740024" ], "modifiers": [], "additional_components": [ "O94740", "SPBC9B6.10", "species_29372", "species_74016", "species_113592", "species_29370", "species_111294", "CHEBI:15996", "species_111349", "species_29926", "species_209914", "species_29420", "O94740", "SPBC9B6.10", "species_29372", "species_74016", "species_113592", "species_29370", "species_29438", "species_111294", "species_29926", "species_209914" ] }, "reaction_10739124": { "compartment": "compartment_114584", "id": "reaction_10739124", "reactome": "R-SPO-429157", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29372", "species_114565" ], "modifiers": [ [ "species_10739121", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10740013": { "compartment": "compartment_876", "id": "reaction_10740013", "reactome": "R-SPO-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739997" ], "products": [ "species_10740011" ], "modifiers": [], "additional_components": [ "P78768", "SPBC3B9.10", "O13998", "SPAC27E2.03c", "O13728", "SPAC15A10.08", "Q9Y7U4", "SPCC645.04", "P78768", "SPBC3B9.10", "O13998", "SPAC27E2.03c", "O13728", "SPAC15A10.08", "Q9Y7U4", "SPCC645.04" ] }, "reaction_10736228": { "compartment": "compartment_984", "id": "reaction_10736228", "reactome": "R-SPO-192430", "name": "Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171126", "species_109276" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10736220", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "Q8TFG4", "SPAPB18E9.04c", "CHEBI:16755", "CHEBI:16359", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274" ] }, "reaction_10755696": { "compartment": "compartment_984", "id": "reaction_10755696", "reactome": "R-SPO-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878780", "species_109276" ], "products": [ "species_109277", "species_8878776" ], "modifiers": [ [ "species_10755693", "catalyst" ] ], "additional_components": [ "species_442320", "O60109", "SPBC14F5.13c", "species_74016" ] }, "reaction_10736223": { "compartment": "compartment_984", "id": "reaction_10736223", "reactome": "R-SPO-192417", "name": "Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171076" ], "products": [ "species_174602", "species_171149" ], "modifiers": [ [ "species_10736220", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "Q8TFG4", "SPAPB18E9.04c", "CHEBI:16755", "CHEBI:16359", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274" ] }, "reaction_10736226": { "compartment": "compartment_984", "id": "reaction_10736226", "reactome": "R-SPO-192425", "name": "Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_6814795" ], "products": [ "species_192438", "species_174602" ], "modifiers": [ [ "species_10736220", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "Q8TFG4", "SPAPB18E9.04c", "CHEBI:16755", "CHEBI:16359", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274" ] }, "reaction_10757949": { "compartment": "compartment_70101", "id": "reaction_10757949", "reactome": "R-SPO-9696275", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757914" ], "products": [ "species_10757916" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10740224": { "compartment": "compartment_70101", "id": "reaction_10740224", "reactome": "R-SPO-548831", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_548809" ], "products": [ "species_29366", "species_428139" ], "modifiers": [ [ "species_10740221", "catalyst" ] ], "additional_components": [ "O94511", "SPBC646.07c" ] }, "reaction_10740231": { "compartment": "compartment_70101", "id": "reaction_10740231", "reactome": "R-SPO-548843", "name": "ACSL3,4 ligate CoA to AA to form AA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_29768", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_548819" ], "modifiers": [ [ "species_10740228", "catalyst" ] ], "additional_components": [ "Q9P7D7", "SPBP4H10.11c", "O60135", "SPBC18H10.02" ] }, "reaction_10747097": { "compartment": "compartment_12045", "id": "reaction_10747097", "reactome": "R-SPO-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_5676634", "species_29356" ], "modifiers": [ [ "species_10747094", "catalyst" ] ], "additional_components": [ "O14346", "SPBC19C2.15c" ] }, "reaction_10736922": { "compartment": "compartment_70101", "id": "reaction_10736922", "reactome": "R-SPO-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_200993" ], "modifiers": [ [ "species_10736919", "catalyst" ] ], "additional_components": [ "Q9P7D7", "SPBP4H10.11c", "O60135", "SPBC18H10.02" ] }, "reaction_10738479": { "compartment": "compartment_876", "id": "reaction_10738479", "reactome": "R-SPO-399998", "name": "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10738476", "catalyst" ] ], "additional_components": [ "P40977", "SPAC22F8.11", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10734981": { "compartment": "compartment_7660", "id": "reaction_10734981", "reactome": "R-SPO-163664", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164121", "species_10734975" ], "products": [ "species_10734979" ], "modifiers": [], "additional_components": [ "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10733346": { "compartment": "compartment_7660", "id": "reaction_10733346", "reactome": "R-SPO-75864", "name": "Newly Formed Phosphodiester Bond Stabilized and PPi Released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733344" ], "products": [ "species_10732713", "species_113541" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10733338": { "compartment": "compartment_7660", "id": "reaction_10733338", "reactome": "R-SPO-75861", "name": "NTP Binds Active Site of RNA Polymerase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733332" ], "products": [ "species_10733336" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10733348": { "compartment": "compartment_7660", "id": "reaction_10733348", "reactome": "R-SPO-75866", "name": "Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733336" ], "products": [ "species_10733344" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10743710": { "compartment": "compartment_7660", "id": "reaction_10743710", "reactome": "R-SPO-2997723", "name": "PIAS4 SUMOylates TP53BP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743694", "species_10743647" ], "products": [ "species_10743639", "species_10743702" ], "modifiers": [ [ "species_10743707", "catalyst" ] ], "additional_components": [ "SPBC342.05", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P87074", "SPBC342.05", "SPAC1687.05" ] }, "reaction_10744668": { "compartment": "compartment_7660", "id": "reaction_10744668", "reactome": "R-SPO-3968414", "name": "UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744646" ], "products": [ "species_10743639", "species_10744663" ], "modifiers": [ [ "species_10744665", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O43058", "SPBC4C3.12", "O13606", "SPBC32H8.11", "SPAC30D11.13", "O43058", "SPBC4C3.12", "O13606", "SPBC32H8.11", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O94451", "SPAC1687.05" ] }, "reaction_10751307": { "compartment": "compartment_7660", "id": "reaction_10751307", "reactome": "R-SPO-6798372", "name": "ATM phosphorylates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10751295" ], "products": [ "species_113582", "species_10751305" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "SPCC23B6.03c" ] }, "reaction_10751322": { "compartment": "compartment_7660", "id": "reaction_10751322", "reactome": "R-SPO-6798373", "name": "MDM2 ubiquitinates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751295", "species_10729044" ], "products": [ "species_10751315" ], "modifiers": [ [ "species_10751319", "catalyst" ] ], "additional_components": [ "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "O74503", "SPCC285.17" ] }, "reaction_10752579": { "compartment": "compartment_7660", "id": "reaction_10752579", "reactome": "R-SPO-6805061", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734359", "species_10752575" ], "products": [ "species_10752577" ], "modifiers": [], "additional_components": [ "O94529", "SPBC609.05", "O94267", "SPBP8B7.19", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11", "O94529", "SPBC609.05", "O94267", "SPBP8B7.19" ] }, "reaction_10745446": { "compartment": "compartment_13231", "id": "reaction_10745446", "reactome": "R-SPO-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10744759", "catalyst" ] ], "additional_components": [ "SPAC1952.13" ] }, "reaction_10744778": { "compartment": "compartment_13231", "id": "reaction_10744778", "reactome": "R-SPO-4419948", "name": "CTDNEP1:CNEP1R1 dephosphorylates LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10744753" ], "products": [ "species_10744759", "species_113550" ], "modifiers": [ [ "species_10744775", "catalyst" ] ], "additional_components": [ "SPAC1952.13", "SPAC1952.13", "Q9USQ0", "SPBC902.03", "O59718", "SPBC3B8.10c" ] }, "reaction_10742056": { "compartment": "compartment_12045", "id": "reaction_10742056", "reactome": "R-SPO-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_109395", "species_1500581" ], "modifiers": [ [ "species_10742053", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "O13901", "SPAC22A12.10" ] }, "reaction_10742027": { "compartment": "compartment_12045", "id": "reaction_10742027", "reactome": "R-SPO-1482900", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498740", "species_1524021" ], "modifiers": [ [ "species_10741849", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742073": { "compartment": "compartment_12045", "id": "reaction_10742073", "reactome": "R-SPO-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_109395", "species_426639" ], "modifiers": [ [ "species_10742070", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "Q10153", "SPAC1D4.08" ] }, "reaction_10742110": { "compartment": "compartment_12045", "id": "reaction_10742110", "reactome": "R-SPO-1483081", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_1524071" ], "products": [ "species_111294", "species_1524060" ], "modifiers": [ [ "species_10742107", "catalyst" ] ], "additional_components": [ "O74975", "SPCC1827.02c" ] }, "reaction_10742173": { "compartment": "compartment_70101", "id": "reaction_10742173", "reactome": "R-SPO-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10742170", "catalyst" ] ], "additional_components": [ "Q10276", "SPAC13G7.12c" ] }, "reaction_10749967": { "compartment": "compartment_12045", "id": "reaction_10749967", "reactome": "R-SPO-5696448", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696449", "species_6782195" ], "products": [ "species_76194", "species_1500596" ], "modifiers": [ [ "species_10749964", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10742021": { "compartment": "compartment_12045", "id": "reaction_10742021", "reactome": "R-SPO-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10740247", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10741961": { "compartment": "compartment_70616", "id": "reaction_10741961", "reactome": "R-SPO-1482745", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524027" ], "modifiers": [ [ "species_10741958", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742032": { "compartment": "compartment_12045", "id": "reaction_10742032", "reactome": "R-SPO-1482920", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498730", "species_1524021" ], "modifiers": [ [ "species_10742029", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10753720": { "compartment": "compartment_12045", "id": "reaction_10753720", "reactome": "R-SPO-8848580", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10753715", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10741907": { "compartment": "compartment_12045", "id": "reaction_10741907", "reactome": "R-SPO-1482685", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10749937": { "compartment": "compartment_17906", "id": "reaction_10749937", "reactome": "R-SPO-5696074", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696069", "species_5696066" ], "products": [ "species_5696026", "species_5696037" ], "modifiers": [ [ "species_10749934", "catalyst" ] ], "additional_components": [ "species_1500596", "species_6814795", "species_1500590", "species_417891", "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04", "species_29926" ] }, "reaction_10741782": { "compartment": "compartment_12045", "id": "reaction_10741782", "reactome": "R-SPO-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_29356" ], "products": [ "species_76116", "species_1500593" ], "modifiers": [ [ "species_10741779", "catalyst" ] ], "additional_components": [ "O94305", "SPCC5E4.05c" ] }, "reaction_10742017": { "compartment": "compartment_12045", "id": "reaction_10742017", "reactome": "R-SPO-1482868", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742037": { "compartment": "compartment_12045", "id": "reaction_10742037", "reactome": "R-SPO-1482932", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498737", "species_1524021" ], "modifiers": [ [ "species_10742034", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741888": { "compartment": "compartment_12045", "id": "reaction_10741888", "reactome": "R-SPO-1482626", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498737", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10741814", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10742002": { "compartment": "compartment_70616", "id": "reaction_10742002", "reactome": "R-SPO-1482847", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524047" ], "modifiers": [ [ "species_10741958", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741852": { "compartment": "compartment_17906", "id": "reaction_10741852", "reactome": "R-SPO-1482604", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590", "species_29356" ], "products": [ "species_1524103", "species_1500580" ], "modifiers": [ [ "species_10741849", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742010": { "compartment": "compartment_12045", "id": "reaction_10742010", "reactome": "R-SPO-1482861", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524069", "species_1500578" ], "products": [ "species_76194", "species_1524081" ], "modifiers": [ [ "species_10733368", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10742120": { "compartment": "compartment_12045", "id": "reaction_10742120", "reactome": "R-SPO-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_426955", "species_111294" ], "modifiers": [ [ "species_10742117", "catalyst" ] ], "additional_components": [ "Q9P381", "SPBC13A2.03", "species_29926" ] }, "reaction_10741807": { "compartment": "compartment_70616", "id": "reaction_10741807", "reactome": "R-SPO-1482546", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524047", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10741804", "catalyst" ] ], "additional_components": [ "SPAC22A12.08c" ] }, "reaction_10741890": { "compartment": "compartment_12045", "id": "reaction_10741890", "reactome": "R-SPO-1482629", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10755107": { "compartment": "compartment_70101", "id": "reaction_10755107", "reactome": "R-SPO-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_426639" ], "products": [ "species_426658", "species_426755" ], "modifiers": [ [ "species_10755104", "catalyst" ] ], "additional_components": [ "Q7LKZ6", "SPCC1020.13c", "P87109", "SPAC20G8.02" ] }, "reaction_10742133": { "compartment": "compartment_12045", "id": "reaction_10742133", "reactome": "R-SPO-1483174", "name": "PE is methylated to PC by PEMT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_71284" ], "products": [ "species_426925", "species_71285" ], "modifiers": [ [ "species_10742130", "catalyst" ] ], "additional_components": [ "SPBC337.16" ] }, "reaction_10741817": { "compartment": "compartment_12045", "id": "reaction_10741817", "reactome": "R-SPO-1482598", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498733", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10741814", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741910": { "compartment": "compartment_70616", "id": "reaction_10741910", "reactome": "R-SPO-1482689", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524027", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10741804", "catalyst" ] ], "additional_components": [ "SPAC22A12.08c" ] }, "reaction_10742063": { "compartment": "compartment_20699", "id": "reaction_10742063", "reactome": "R-SPO-1482973", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524057", "species_1524060" ], "products": [ "species_109395", "species_429785" ], "modifiers": [ [ "species_10742060", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "O13901", "SPAC22A12.10" ] }, "reaction_10742015": { "compartment": "compartment_12045", "id": "reaction_10742015", "reactome": "R-SPO-1482867", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524080", "species_1500578" ], "products": [ "species_76194", "species_1524069" ], "modifiers": [ [ "species_10733368", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10741893": { "compartment": "compartment_12045", "id": "reaction_10741893", "reactome": "R-SPO-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10741772", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10741885": { "compartment": "compartment_12045", "id": "reaction_10741885", "reactome": "R-SPO-1482612", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742091": { "compartment": "compartment_70101", "id": "reaction_10742091", "reactome": "R-SPO-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_264618" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10742088", "catalyst" ] ], "additional_components": [ "Q10276", "SPAC13G7.12c" ] }, "reaction_10742153": { "compartment": "compartment_12045", "id": "reaction_10742153", "reactome": "R-SPO-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_428686" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10742150", "catalyst" ] ], "additional_components": [ "Q9UTI6", "SPAC15E1.05c" ] }, "reaction_10742094": { "compartment": "compartment_70616", "id": "reaction_10742094", "reactome": "R-SPO-1483063", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_1524064" ], "products": [ "species_1524067", "species_1524072" ], "modifiers": [ [ "species_10741804", "catalyst" ] ], "additional_components": [ "SPAC22A12.08c" ] }, "reaction_10741980": { "compartment": "compartment_70616", "id": "reaction_10741980", "reactome": "R-SPO-1482759", "name": "MLCL is hydrolyzed to DLCL by PLA2G4A (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498773", "species_113521" ], "products": [ "species_1524085", "species_1498753" ], "modifiers": [ [ "species_10741977", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741902": { "compartment": "compartment_70101", "id": "reaction_10741902", "reactome": "R-SPO-1482656", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10741849", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10733396": { "compartment": "compartment_70101", "id": "reaction_10733396", "reactome": "R-SPO-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_75970" ], "products": [ "species_29360", "species_76114" ], "modifiers": [ [ "species_10733393", "catalyst" ] ], "additional_components": [ "Q09845", "SPAC23D3.04c", "P21696", "SPBC215.05" ] }, "reaction_10749957": { "compartment": "compartment_5460", "id": "reaction_10749957", "reactome": "R-SPO-5696415", "name": "PXLP-K278-ETNPPL tetramer hydrolyses PETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_5696414" ], "products": [ "species_113548", "species_5693978", "species_113532" ], "modifiers": [ [ "species_10749954", "catalyst" ] ], "additional_components": [ "Q9US34", "SPAC1039.07c" ] }, "reaction_10741914": { "compartment": "compartment_12045", "id": "reaction_10741914", "reactome": "R-SPO-1482696", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10750442": { "compartment": "compartment_70101", "id": "reaction_10750442", "reactome": "R-SPO-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10750439", "catalyst" ] ], "additional_components": [ "Q7LKZ6", "SPCC1020.13c", "P87109", "SPAC20G8.02" ] }, "reaction_10741991": { "compartment": "compartment_12045", "id": "reaction_10741991", "reactome": "R-SPO-1482825", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10741988", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742143": { "compartment": "compartment_12045", "id": "reaction_10742143", "reactome": "R-SPO-1483182", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_264618", "species_426755" ], "modifiers": [ [ "species_10742138", "catalyst" ] ], "additional_components": [ "SPAC2F7.16c" ] }, "reaction_10741775": { "compartment": "compartment_12045", "id": "reaction_10741775", "reactome": "R-SPO-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498740", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10741772", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10733373": { "compartment": "compartment_12045", "id": "reaction_10733373", "reactome": "R-SPO-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_76194", "species_426755" ], "modifiers": [ [ "species_10733370", "catalyst" ] ], "additional_components": [ "O94361", "SPBC428.14", "Q9US20", "SPAC1851.02" ] }, "reaction_10755689": { "compartment": "compartment_5460", "id": "reaction_10755689", "reactome": "R-SPO-8878654", "name": "ACP6 hydrolyses MYS-LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878649", "species_113521" ], "products": [ "species_8934414", "species_113548" ], "modifiers": [ [ "species_10755686", "catalyst" ] ], "additional_components": [ "SPBC4.06" ] }, "reaction_10742164": { "compartment": "compartment_12045", "id": "reaction_10742164", "reactome": "R-SPO-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10742161", "catalyst" ] ], "additional_components": [ "Q9UUJ6", "SPAC1952.13", "species_29926" ] }, "reaction_10742047": { "compartment": "compartment_12045", "id": "reaction_10742047", "reactome": "R-SPO-1482961", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524060", "species_1500596" ], "products": [ "species_109395", "species_426925" ], "modifiers": [ [ "species_10742044", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "O13901", "SPAC22A12.10" ] }, "reaction_10756967": { "compartment": "compartment_70101", "id": "reaction_10756967", "reactome": "R-SPO-9018824", "name": "RHOT2 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756963", "species_10756946" ], "products": [ "species_10756965" ], "modifiers": [], "additional_components": [ "O74805", "SPBC2D10.14c", "Q9USY7", "SPBC1706.03", "O94477", "SPCC1919.10c", "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "O74805", "SPBC2D10.14c", "Q9USY7", "SPBC1706.03", "species_29438", "O94477", "SPCC1919.10c" ] }, "reaction_10756969": { "compartment": "compartment_70101", "id": "reaction_10756969", "reactome": "R-SPO-9018826", "name": "RHOT2 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756946", "species_29356" ], "products": [ "species_10756948", "species_29372" ], "modifiers": [ [ "species_10756946", "catalyst" ] ], "additional_components": [ "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "species_29420", "O59781", "SPCC320.04c", "species_29438" ] }, "reaction_10757850": { "compartment": "compartment_876", "id": "reaction_10757850", "reactome": "R-SPO-9693111", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757845" ], "products": [ "species_10757847", "species_29420" ], "modifiers": [ [ "species_10757845", "catalyst" ] ], "additional_components": [ "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01" ] }, "reaction_10757896": { "compartment": "compartment_876", "id": "reaction_10757896", "reactome": "R-SPO-9693282", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757847", "species_29356" ], "products": [ "species_29372", "species_10757845" ], "modifiers": [ [ "species_10756838", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10752557": { "compartment": "compartment_7660", "id": "reaction_10752557", "reactome": "R-SPO-6804955", "name": "ATM phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737757" ], "products": [ "species_113582", "species_10752555" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "SPCC23B6.03c" ] }, "reaction_10755684": { "compartment": "compartment_7660", "id": "reaction_10755684", "reactome": "R-SPO-8877692", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740775", "species_10755677" ], "products": [ "species_10755682" ], "modifiers": [], "additional_components": [ "SPCC16C4.03", "O13853", "SPAC19G12.14", "O74448", "SPCC16C4.03", "O13853", "SPAC19G12.14" ] }, "reaction_10737784": { "compartment": "compartment_7660", "id": "reaction_10737784", "reactome": "R-SPO-349455", "name": "Phosphorylation of MDM4 by ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737774" ], "products": [ "species_113582", "species_10737762" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "O74503", "SPCC285.17", "SPCC23B6.03c" ] }, "reaction_10751191": { "compartment": "compartment_70101", "id": "reaction_10751191", "reactome": "R-SPO-6793666", "name": "MDM2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736549" ], "products": [ "species_10737757" ], "modifiers": [], "additional_components": [ "SPCC285.17", "SPCC285.17" ] }, "reaction_10752603": { "compartment": "compartment_7660", "id": "reaction_10752603", "reactome": "R-SPO-6805640", "name": "AKT phosphorylates KAT6A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10752596" ], "products": [ "species_113582", "species_10752601" ], "modifiers": [ [ "species_10736722", "catalyst" ] ], "additional_components": [ "O14240", "SPAC6F6.09", "O74736", "SPBC1709.11c", "O94446", "SPAC637.12c", "O42871", "SPAC3G9.08", "O14240", "SPAC6F6.09", "O74736", "SPBC1709.11c", "O94446", "SPAC637.12c", "O42871", "SPAC3G9.08", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10752539": { "compartment": "compartment_7660", "id": "reaction_10752539", "reactome": "R-SPO-6804724", "name": "MDM2 ubiquitinates phosphorylated MDM4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737768", "species_10729044" ], "products": [ "species_10752536" ], "modifiers": [ [ "species_10737768", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74503", "SPCC285.17", "O74503", "SPCC285.17" ] }, "reaction_10751207": { "compartment": "compartment_70101", "id": "reaction_10751207", "reactome": "R-SPO-6795290", "name": "TORC2 complex phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10751197" ], "products": [ "species_29370", "species_10751205" ], "modifiers": [ [ "species_10736612", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "O14208", "SPAC6B12.03c", "Q09743", "SPBC12C2.02c", "Q9Y7K2", "SPBC216.07c", "O74547", "SPCC777.08c", "O74184", "SPBC21B10.05c", "Q9P7Y9", "SPAPYUG7.02c" ] }, "reaction_10751220": { "compartment": "compartment_70101", "id": "reaction_10751220", "reactome": "R-SPO-6795473", "name": "PDPK1 phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10751205" ], "products": [ "species_29370", "species_10751215" ], "modifiers": [ [ "species_10733718", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10752549": { "compartment": "compartment_7660", "id": "reaction_10752549", "reactome": "R-SPO-6804942", "name": "MDM2 homodimers auto-ubiquitinate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751317", "species_10729044" ], "products": [ "species_10752546" ], "modifiers": [ [ "species_10751317", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74503", "SPCC285.17", "O74503", "SPCC285.17" ] }, "reaction_10751189": { "compartment": "compartment_7660", "id": "reaction_10751189", "reactome": "R-SPO-6793661", "name": "(CDK1,CDK2):CCNA phosphorylates MDM2 at T218", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737757" ], "products": [ "species_113582", "species_10751172" ], "modifiers": [ [ "species_10728937", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10753231": { "compartment": "compartment_7660", "id": "reaction_10753231", "reactome": "R-SPO-6810376", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744714", "species_6810408" ], "products": [ "species_10753229" ], "modifiers": [], "additional_components": [ "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08", "species_422529", "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08" ] }, "reaction_10737770": { "compartment": "compartment_7660", "id": "reaction_10737770", "reactome": "R-SPO-349426", "name": "Phosphorylation of MDM4 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737762" ], "products": [ "species_113582", "species_10737768" ], "modifiers": [ [ "species_10729617", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "O74503", "SPCC285.17", "SPAC14C4.03" ] }, "reaction_10751222": { "compartment": "compartment_70101", "id": "reaction_10751222", "reactome": "R-SPO-6795667", "name": "MDM2 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743716" ], "products": [ "species_10736545" ], "modifiers": [], "additional_components": [ "SPCC285.17", "SPCC285.17" ] }, "reaction_10752543": { "compartment": "compartment_7660", "id": "reaction_10752543", "reactome": "R-SPO-6804741", "name": "MDM2 forms homo- or heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752541", "species_10737757" ], "products": [ "species_10751319" ], "modifiers": [ [ "species_10737781", "inhibitor" ] ], "additional_components": [ "O74503", "SPCC285.17", "SPCC285.17", "O74503", "SPCC285.17", "SPCC23B6.03c" ] }, "reaction_10755680": { "compartment": "compartment_7660", "id": "reaction_10755680", "reactome": "R-SPO-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10755666" ], "products": [ "species_113582", "species_10755677" ], "modifiers": [ [ "species_10739756", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14", "O13853", "SPAC19G12.14", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c" ] }, "reaction_10751218": { "compartment": "compartment_70101", "id": "reaction_10751218", "reactome": "R-SPO-6795460", "name": "SGK1 phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736545", "species_113592" ], "products": [ "species_29370", "species_10736549" ], "modifiers": [ [ "species_10751215", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10751262": { "compartment": "compartment_7660", "id": "reaction_10751262", "reactome": "R-SPO-6797616", "name": "CCNK:CDK12 binds RNA Pol II at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751226", "species_10751242" ], "products": [ "species_10751244" ], "modifiers": [], "additional_components": [ "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c" ] }, "reaction_10751260": { "compartment": "compartment_7660", "id": "reaction_10751260", "reactome": "R-SPO-6797606", "name": "CDK12 phosphorylates RNA Pol II CTD at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10751244" ], "products": [ "species_113582", "species_10751257" ], "modifiers": [ [ "species_10751244", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c" ] }, "reaction_10751234": { "compartment": "compartment_7660", "id": "reaction_10751234", "reactome": "R-SPO-6797100", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734263", "species_10751230" ], "products": [ "species_10751232" ], "modifiers": [], "additional_components": [ "SPBC32F12.06", "SPAC2F3.15", "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15" ] }, "reaction_10751228": { "compartment": "compartment_7660", "id": "reaction_10751228", "reactome": "R-SPO-6797090", "name": "CCNK binds CDK12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734263", "species_10751224" ], "products": [ "species_10751226" ], "modifiers": [], "additional_components": [ "SPBC32F12.06", "SPAC2F3.15", "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15" ] }, "reaction_10739697": { "compartment": "compartment_5460", "id": "reaction_10739697", "reactome": "R-SPO-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113539", "species_113593" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10739694", "catalyst" ] ], "additional_components": [ "SPCC191.02c" ] }, "reaction_10730535": { "compartment": "compartment_70101", "id": "reaction_10730535", "reactome": "R-SPO-71707", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30203", "species_29360" ], "products": [ "species_70106", "species_73473", "species_29510" ], "modifiers": [ [ "species_10730532", "catalyst" ] ], "additional_components": [ "species_442320", "P78870", "SPCC13B11.04c", "O74540", "SPCC13B11.04c" ] }, "reaction_10730567": { "compartment": "compartment_70101", "id": "reaction_10730567", "reactome": "R-SPO-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_113592", "species_29416" ], "products": [ "species_111294", "species_76577", "species_76183" ], "modifiers": [ [ "species_10730564", "catalyst" ] ], "additional_components": [ "SPCC191.02c" ] }, "reaction_10745912": { "compartment": "compartment_876", "id": "reaction_10745912", "reactome": "R-SPO-5433067", "name": "DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490235" ], "products": [ "species_266029", "species_5490250" ], "modifiers": [ [ "species_10737679", "catalyst" ] ], "additional_components": [ "CHEBI:78579", "CHEBI:78584", "CHEBI:78578", "CHEBI:78583", "O59832", "SPCC965.12", "species_442320", "O14124", "SPCC965.12" ] }, "reaction_10730490": { "compartment": "compartment_70101", "id": "reaction_10730490", "reactome": "R-SPO-71691", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29510", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_29416" ], "modifiers": [ [ "species_10730487", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10730542": { "compartment": "compartment_5460", "id": "reaction_10730542", "reactome": "R-SPO-71723", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730539", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10749939": { "compartment": "compartment_5460", "id": "reaction_10749939", "reactome": "R-SPO-5696091", "name": "ALDH1B1 tetramer oxidises CH3CHO to CH3COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730539", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10745935": { "compartment": "compartment_984", "id": "reaction_10745935", "reactome": "R-SPO-5433072", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490253", "species_109276" ], "products": [ "species_210382", "species_5490235" ], "modifiers": [ [ "species_10745932", "catalyst" ] ], "additional_components": [ "CHEBI:78587", "CHEBI:78581", "CHEBI:78579", "CHEBI:78584", "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10749510": { "compartment": "compartment_70101", "id": "reaction_10749510", "reactome": "R-SPO-5692237", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692221", "species_29360" ], "products": [ "species_73473", "species_70106", "species_5692249" ], "modifiers": [ [ "species_10749507", "catalyst" ] ], "additional_components": [ "species_442320", "O74540", "SPCC13B11.04c" ] }, "reaction_10747760": { "compartment": "compartment_12045", "id": "reaction_10747760", "reactome": "R-SPO-5689000", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5689006", "species_29356" ], "products": [ "species_5688995", "species_5689001" ], "modifiers": [ [ "species_10747757", "catalyst" ] ], "additional_components": [ "Q9US38", "SPAPB1A11.02", "Q9HDX3", "SPAPB1A11.02" ] }, "reaction_10734961": { "compartment": "compartment_5460", "id": "reaction_10734961", "reactome": "R-SPO-163310", "name": "TFAM binds to mitochondrial promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163305", "species_10734957" ], "products": [ "species_10734959" ], "modifiers": [], "additional_components": [ "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c", "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c" ] }, "reaction_10743032": { "compartment": "compartment_7660", "id": "reaction_10743032", "reactome": "R-SPO-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10743025", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10743029" ], "modifiers": [ [ "species_10743025", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "species_113531", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "O94603", "SPCC622.16c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "species_113531", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "O94603", "SPCC622.16c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "species_113531", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "O94603", "SPCC622.16c" ] }, "reaction_10758000": { "compartment": "compartment_12045", "id": "reaction_10758000", "reactome": "R-SPO-9714361", "name": "RHOC activates endoplasmic reticulum effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757996", "species_10757971" ], "products": [ "species_10757998" ], "modifiers": [], "additional_components": [ "O13644", "SPBC8D2.14c", "O42707", "SPCC126.08c", "Q09195", "SPBC16G5.18", "Q10484", "SPAC17C9.12", "O94401", "SPCC126.08c", "O60119", "SPBC16G5.05c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "O13644", "SPBC8D2.14c", "Q9HE04", "SPAC20H4.11c", "O42707", "SPCC126.08c", "Q09195", "SPBC16G5.18", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q10484", "SPAC17C9.12", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O94401", "SPCC126.08c", "species_29438", "O60119", "SPBC16G5.05c" ] }, "reaction_10758002": { "compartment": "compartment_876", "id": "reaction_10758002", "reactome": "R-SPO-9714363", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746673" ], "products": [ "species_10757971" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10756748": { "compartment": "compartment_876", "id": "reaction_10756748", "reactome": "R-SPO-9013111", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746673", "species_29356" ], "products": [ "species_10756724", "species_29372" ], "modifiers": [ [ "species_10756508", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10756740": { "compartment": "compartment_70101", "id": "reaction_10756740", "reactome": "R-SPO-9013108", "name": "GDIs block activation of RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756724", "species_10756674" ], "products": [ "species_10756738" ], "modifiers": [], "additional_components": [ "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "SPAC6F12.06", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O14224", "SPAC6F12.06" ] }, "reaction_10756746": { "compartment": "compartment_876", "id": "reaction_10756746", "reactome": "R-SPO-9013110", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746673", "species_10756742" ], "products": [ "species_10756744" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q10201", "SPBC17D1.07c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "P78953", "SPCC4B3.15", "Q92356", "SPAC6G9.11", "O14188", "SPAC4F8.13c", "O43027", "SPBC354.13", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "O43027", "SPBC354.13", "Q10133", "SPAC16.01", "species_29438", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c" ] }, "reaction_10736357": { "compartment": "compartment_70101", "id": "reaction_10736357", "reactome": "R-SPO-196060", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_196095" ], "products": [ "species_29366", "species_196066" ], "modifiers": [ [ "species_10736354", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10744363": { "compartment": "compartment_7660", "id": "reaction_10744363", "reactome": "R-SPO-3662318", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732874", "species_113560" ], "products": [ "species_2485002", "species_10744336" ], "modifiers": [ [ "species_10744360", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "Q9UTM7", "SPAC139.06", "O94244", "SPCC1672.10" ] }, "reaction_10744059": { "compartment": "compartment_7660", "id": "reaction_10744059", "reactome": "R-SPO-3318415", "name": "ATF2 acetylates histone H2B, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744046", "species_113560" ], "products": [ "species_2485002", "species_10744056" ], "modifiers": [ [ "species_10735245", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04913", "SPCC622.09", "P09322", "SPAC1834.03c", "P04913", "SPCC622.09", "P52890", "SPBC29B5.01", "P78962", "SPBC2F12.09c", "Q09771", "SPAC22F3.02" ] }, "reaction_10756972": { "compartment": "compartment_70101", "id": "reaction_10756972", "reactome": "R-SPO-9018862", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9022655" ], "products": [ "species_9022660" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10742548": { "compartment": "compartment_70101", "id": "reaction_10742548", "reactome": "R-SPO-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742542", "species_10742544" ], "products": [ "species_10742546" ], "modifiers": [], "additional_components": [ "P21565", "SPCC188.06c", "O74436", "SPCC1682.05c", "O59787", "SPCC320.10", "O13804", "SPAC17H9.07", "O94407", "SPCC126.15c", "Q9P372", "SPAC19B12.09", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", 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"Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740756" ], "products": [ "species_10733183", "species_10740705", "species_10734667", "species_10740725", "species_10740717", "species_10731799", "species_10740723", "species_10740674" ], "modifiers": [ [ "species_10740705", "catalyst" ], [ "species_10740752", "catalyst" ] ], "additional_components": [ "Q9P6M8", "SPAC1610.03c", "Q10475", "SPAC17C9.03", "P31209", "SPAC57A7.04c", "Q09820", "SPAC16C9.06c", "O14338", "SPBC2F12.03c", "Q9UT08", "SPAP8A3.09c", "Q9P383", "SPBC13A2.01c", "P23636", "SPBC16H5.07c", "O14253", "SPAC6G10.07", "O74804", "SPBC2D10.13", "Q12702", "SPAC57A7.04c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "Q9P6M8", "SPAC1610.03c", "P31209", "SPAC57A7.04c", "SPBC2D10.13", "O14338", "SPBC2F12.03c", "O74804", "SPBC2D10.13", "SPAC17C9.03", "O14338", "SPBC2F12.03c", "O74804", "SPBC2D10.13", "SPAC16C9.06c", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "SPAC16C9.06c" ] }, "reaction_10740770": { "compartment": "compartment_70101", "id": "reaction_10740770", "reactome": "R-SPO-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740767", "species_113592" ], "products": [ "species_29370", "species_10740754" ], "modifiers": [ [ "species_10740767", "catalyst" ] ], "additional_components": [ "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", 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"SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "O43037", "SPBC3B9.08c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "Q10267", "SPAC13G7.03", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "Q1MTR2", "SPBC13G1.14c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07" ] }, "reaction_10740765": { "compartment": "compartment_70101", "id": "reaction_10740765", "reactome": "R-SPO-927836", "name": "SMG6 hydrolyzes mRNA with premature termination codon", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740762" ], "products": [ "species_10740756" ], "modifiers": [ [ "species_10740762", "catalyst" ] ], "additional_components": [ "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "Q12702", "SPAC57A7.04c", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "Q9UT08", "SPAP8A3.09c", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", 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"Q09757", "SPAC24H6.07", "Q10055", "SPAC1F5.10", "P05764", "SPBC18E5.06", "O42699", "SPCC1682.14", "O13824", "SPAC19A8.08", "P0CT83", "SPCC16C4.13c", "Q9P4W9", "SPAC959.07", "P23636", "SPBC16H5.07c", "Q9US22", "SPAC1783.08c", "O74172", "SPBC3D6.15", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "Q9P546", "SPAPJ698.02c", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "O43037", "SPBC3B9.08c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "Q10267", "SPAC13G7.03", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "O74804", "SPBC2D10.13", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "O14338", "SPBC2F12.03c", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "Q1MTR2", "SPBC13G1.14c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07" ] }, "reaction_10755910": { "compartment": "compartment_876", "id": "reaction_10755910", "reactome": "R-SPO-8941234", "name": "SH3PXD2A binds ADAM12,ADAM15,ADAM19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755902", "species_10755900" ], "products": [ "species_10755908" ], "modifiers": [], "additional_components": [ "SPAC17A5.04c", "species_202247", "P40996", "SPAC22H10.07", "species_202247", "P40996", "SPAC22H10.07", "O13766", "SPAC17A5.04c" ] }, "reaction_10740377": { "compartment": "compartment_70101", "id": "reaction_10740377", "reactome": "R-SPO-893596", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29970" ], "products": [ "species_893615", "species_29432" ], "modifiers": [ [ "species_10740371", "catalyst" ], [ "species_8939576", "inhibitor" ], [ "species_29502", "inhibitor" ] ], "additional_components": [ "O14209", "SPAC6B12.04c", "CHEBI:55528", "CHEBI:43580" ] }, "reaction_10749439": { "compartment": "compartment_70101", "id": "reaction_10749439", "reactome": "R-SPO-5690319", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10749434" ], "products": [ "species_1131871", "species_10749436" ], "modifiers": [ [ "species_10749434", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10171", "SPAC27F1.03c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10171", "SPAC27F1.03c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10171", "SPAC27F1.03c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10744634": { "compartment": "compartment_7660", "id": "reaction_10744634", "reactome": "R-SPO-3968362", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10743707" ], "products": [ "species_10743639", "species_10744632" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC1687.05", "SPAC30D11.13", "O13351", "SPBC365.06", "O94451", "SPAC1687.05", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750477": { "compartment": "compartment_12045", "id": "reaction_10750477", "reactome": "R-SPO-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_6788758", "species_71285" ], "modifiers": [ [ "species_10750474", "catalyst" ] ], "additional_components": [ "species_442320", "P87014", "SPAC10F6.12c" ] }, "reaction_10734835": { "compartment": "compartment_70101", "id": "reaction_10734835", "reactome": "R-SPO-162730", "name": "phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_162756" ], "products": [ "species_110096", "species_8855657" ], "modifiers": [ [ "species_10734832", "catalyst" ] ], "additional_components": [ "O59802", "SPCC550.04c", "Q9USW6", "SPBC21B10.11", "P87172", "SPBC3D6.07", "Q9Y7L7", "SPBC685.05", "O13904", "SPAC22A12.13", "O14357", "SPBC30D10.11" ] }, "reaction_10744958": { "compartment": "compartment_7660", "id": "reaction_10744958", "reactome": "R-SPO-4615873", "name": "PIAS2-2 SUMOylates SUZ12 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744943" ], "products": [ "species_10743639", "species_10744956" ], "modifiers": [ [ "species_10743728", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O94522", "SPCC1281.05", "O74792", "SPBC26H8.09c", "SPAC30D11.13", "O13351", "SPBC365.06", "O94522", "SPCC1281.05", "O74792", "SPBC26H8.09c", "SPAC1687.05" ] }, "reaction_10745032": { "compartment": "compartment_7660", "id": "reaction_10745032", "reactome": "R-SPO-4641362", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10745022" ], "products": [ "species_10745030", "species_10743639" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC1703.14c", "P07799", "SPBC1703.14c", "O13351", "SPBC365.06", "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10739546": { "compartment": "compartment_17957", "id": "reaction_10739546", "reactome": "R-SPO-446202", "name": "Addition of the first glucose to the N-glycan precursor by ALG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449371", "species_532542" ], "products": [ "species_449311", "species_449649" ], "modifiers": [ [ "species_10739543", "catalyst" ] ], "additional_components": [ "SPBC342.01c" ] }, "reaction_10740200": { "compartment": "compartment_70101", "id": "reaction_10740200", "reactome": "R-SPO-532549", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_532562" ], "modifiers": [ [ "species_10740197", "catalyst" ] ], "additional_components": [ "SPBC2G2.16" ] }, "reaction_10734722": { "compartment": "compartment_70101", "id": "reaction_10734722", "reactome": "R-SPO-156910", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734718", "species_10734713", "species_10734711" ], "products": [ "species_10734720" ], "modifiers": [], "additional_components": [ "SPAC29A4.02c", "SPCC1450.04", "SPCC1450.04", "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04" ] }, "reaction_10755736": { "compartment": "compartment_70101", "id": "reaction_10755736", "reactome": "R-SPO-8879123", "name": "PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731529", "species_71284" ], "products": [ "species_71285", "species_10755728" ], "modifiers": [ [ "species_10755733", "catalyst" ] ], "additional_components": [ "SPCC576.08c", "SPCC576.08c", "SPBC8D2.10c" ] }, "reaction_10744624": { "compartment": "compartment_7660", "id": "reaction_10744624", "reactome": "R-SPO-3900177", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10730920" ], "products": [ "species_10743639", "species_10744622" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBP8B7.16c", "SPAC30D11.13", "O13351", "SPBC365.06", "P24782", "SPBP8B7.16c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750113": { "compartment": "compartment_70101", "id": "reaction_10750113", "reactome": "R-SPO-6781797", "name": "USP19 binds HIF1A,BIRC2,BIRC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737150", "species_10750109" ], "products": [ "species_10750111" ], "modifiers": [], "additional_components": [ "SPCC962.02c", "SPBC18H10.08c", "O60139", "SPBC18H10.08c", "O14064", "SPCC962.02c" ] }, "reaction_10744889": { "compartment": "compartment_7660", "id": "reaction_10744889", "reactome": "R-SPO-4570496", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732874", "species_10743647" ], "products": [ "species_10743639", "species_10744887" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "P09322", "SPAC1834.03c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750212": { "compartment": "compartment_70101", "id": "reaction_10750212", "reactome": "R-SPO-6781953", "name": "YOD1 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745608", "species_10750208" ], "products": [ "species_10750210" ], "modifiers": [], "additional_components": [ "SPAC1565.08", "SPAC24C9.14", "O13974", "SPAC24C9.14", "Q9P3A7", "SPAC1565.08" ] }, "reaction_10737483": { "compartment": "compartment_70101", "id": "reaction_10737483", "reactome": "R-SPO-204617", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_204628", "species_10737463" ], "products": [ "species_29360", "species_204635", "species_10737473" ], "modifiers": [ [ "species_10737480", "catalyst" ] ], "additional_components": [ "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "O94337", "SPBC1271.04c" ] }, "reaction_10746712": { "compartment": "compartment_70101", "id": "reaction_10746712", "reactome": "R-SPO-5665871", "name": "ADRM1 binds 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729366", "species_10746683" ], "products": [ "species_10746685" ], "modifiers": [], "additional_components": [ "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13", "SPBC342.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10755788": { "compartment": "compartment_70101", "id": "reaction_10755788", "reactome": "R-SPO-8932276", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745608", "species_71284" ], "products": [ "species_71285", "species_10755776" ], "modifiers": [ [ "species_10755785", "catalyst" ] ], "additional_components": [ "SPAC1565.08", "SPAC1565.08", "O13926", "SPAC23C4.06c", "P87241", "SPCC4G3.16" ] }, "reaction_10750092": { "compartment": "compartment_7660", "id": "reaction_10750092", "reactome": "R-SPO-5697009", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10750085" ], "products": [ "species_10750089", "species_10748683" ], "modifiers": [ [ "species_10750085", "catalyst" ] ], "additional_components": [ "P41836", "SPBC23G7.12c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "Q9C0X6", "SPAPB8E5.09", "P25009", "SPBC19F5.01c", "Q9P7V9", "SPBC1703.12", "P41836", "SPBC23G7.12c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "Q9C0X6", "SPAPB8E5.09", "P25009", "SPBC19F5.01c", "Q9P7V9", "SPBC1703.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P41836", "SPBC23G7.12c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "Q9C0X6", "SPAPB8E5.09", "P25009", "SPBC19F5.01c", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10746689": { "compartment": "compartment_70101", "id": "reaction_10746689", "reactome": "R-SPO-5665854", "name": "ADRM1:26S proteaseome binds UCHL5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746685", "species_10746678" ], "products": [ "species_10746687" ], "modifiers": [], "additional_components": [ "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13", "SPBC409.06", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "Q9UUB6", "SPBC409.06", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10734866": { "compartment": "compartment_12045", "id": "reaction_10734866", "reactome": "R-SPO-162798", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_8855659" ], "products": [ "species_8855663", "species_1500596" ], "modifiers": [ [ "species_10734863", "catalyst" ] ], "additional_components": [ "SPBC839.08c" ] }, "reaction_10744744": { "compartment": "compartment_7660", "id": "reaction_10744744", "reactome": "R-SPO-4090284", "name": "SUMOylation of HIPK2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744734", "species_10743647" ], "products": [ "species_10743639", "species_10744742" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC823.03", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "Q9P6P3", "SPAC823.03", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10745739": { "compartment": "compartment_70101", "id": "reaction_10745739", "reactome": "R-SPO-5358494", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745719", "species_71284" ], "products": [ "species_10745706", "species_353106" ], "modifiers": [ [ "species_10745736", "catalyst" ] ], "additional_components": [ "SPAC513.01c", "SPAC513.01c", "Q10206", "SPBC17D1.02", "Q9UT33", "SPAC8F11.02c", "O59713", "SPBC3B8.05" ] }, "reaction_10739520": { "compartment": "compartment_17957", "id": "reaction_10739520", "reactome": "R-SPO-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449312", "species_449229" ], "products": [ "species_449311", "species_449365" ], "modifiers": [ [ "species_10739517", "catalyst" ] ], "additional_components": [ "SPBC1734.12c" ] }, "reaction_10739488": { "compartment": "compartment_17957", "id": "reaction_10739488", "reactome": "R-SPO-446188", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449298", "species_449229" ], "products": [ "species_449311", "species_449315" ], "modifiers": [ [ "species_10739485", "catalyst" ] ], "additional_components": [ "SPAC7D4.06c" ] }, "reaction_10734874": { "compartment": "compartment_12045", "id": "reaction_10734874", "reactome": "R-SPO-162821", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855667", "species_449229" ], "products": [ "species_8855656", "species_162872" ], "modifiers": [ [ "species_10734871", "catalyst" ] ], "additional_components": [ "SPCC16A11.06c" ] }, "reaction_10750032": { "compartment": "compartment_7660", "id": "reaction_10750032", "reactome": "R-SPO-5696605", "name": "USP12, USP26 deubiquitinate AR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750027", "species_113518" ], "products": [ "species_10750029", "species_10748683" ], "modifiers": [ [ "species_10750027", "catalyst" ] ], "additional_components": [ "Q10437", "SPAC12B10.03", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "Q10437", "SPAC12B10.03", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q10437", "SPAC12B10.03", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10745006": { "compartment": "compartment_7660", "id": "reaction_10745006", "reactome": "R-SPO-4641342", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744996", "species_10743647" ], "products": [ "species_10743639", "species_10745004" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPBC1A4.03c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "P08096", "SPBC1A4.03c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10737507": { "compartment": "compartment_70101", "id": "reaction_10737507", "reactome": "R-SPO-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10737463", "species_29368" ], "products": [ "species_29360", "species_10737497", "species_29356" ], "modifiers": [ [ "species_10737504", "catalyst" ] ], "additional_components": [ "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "Q9P6K9", "SPAC30C2.02", "species_113531" ] }, "reaction_10744694": { "compartment": "compartment_7660", "id": "reaction_10744694", "reactome": "R-SPO-4085350", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743639", "species_10743647" ], "products": [ "species_10743639", "species_10744692" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750295": { "compartment": "compartment_7660", "id": "reaction_10750295", "reactome": "R-SPO-6782820", "name": "USP17 deubiquitinates SUDS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10750290" ], "products": [ "species_10750292", "species_10748291" ], "modifiers": [ [ "species_10750290", "catalyst" ] ], "additional_components": [ "O74442", "SPCC1682.12c", "Q9P7M1", "SPBC21C3.02c", "O74442", "SPCC1682.12c", "Q9P7M1", "SPBC21C3.02c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74442", "SPCC1682.12c", "Q9P7M1", "SPBC21C3.02c" ] }, "reaction_10734882": { "compartment": "compartment_70101", "id": "reaction_10734882", "reactome": "R-SPO-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_29416", "species_8855661" ], "modifiers": [ [ "species_10734879", "catalyst" ] ], "additional_components": [ "SPAPB2B4.01c" ] }, "reaction_10748686": { "compartment": "compartment_7660", "id": "reaction_10748686", "reactome": "R-SPO-5689950", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747837" ], "products": [ "species_10748683", "species_10747843" ], "modifiers": [ [ "species_10747837", "catalyst" ] ], "additional_components": [ "Q09879", "SPCC188.08c", "O74503", "SPCC285.17", "O94526", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09879", "SPCC188.08c", "O74503", "SPCC285.17", "O94526", "SPBC609.02", "Q09879", "SPCC188.08c", "O74503", "SPCC285.17", "O94526", "SPBC609.02" ] }, "reaction_10734803": { "compartment": "compartment_12045", "id": "reaction_10734803", "reactome": "R-SPO-162721", "name": "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449299" ], "products": [ "species_162681", "species_29420" ], "modifiers": [ [ "species_10734800", "catalyst" ] ], "additional_components": [ "O94633", "SPBC1677.02", "Q9USW6", "SPBC21B10.11", "O14466", "SPAC31G5.16c" ] }, "reaction_10752208": { "compartment": "compartment_70101", "id": "reaction_10752208", "reactome": "R-SPO-6800138", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10752186" ], "products": [ "species_10752193", "species_71285" ], "modifiers": [ [ "species_10752205", "catalyst" ] ], "additional_components": [ "O74718", "SPCC584.04", "P79063", "SPAC1834.01", "species_29438", "O74718", "SPCC584.04", "P79063", "SPAC1834.01", "species_29438", "Q9UT94", "SPAC323.05c", "Q09723", "SPAC31A2.02" ] }, "reaction_10744991": { "compartment": "compartment_7660", "id": "reaction_10744991", "reactome": "R-SPO-4616015", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744524" ], "products": [ "species_10743639", "species_10744989" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC36.05c", "SPAC30D11.13", "O59702", "SPBC36.05c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744684": { "compartment": "compartment_7660", "id": "reaction_10744684", "reactome": "R-SPO-4085331", "name": "PIAS2-1 SUMOylates PARK7 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744673" ], "products": [ "species_10743639", "species_10744681" ], "modifiers": [ [ "species_10743728", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC22E12.03c", "SPAC30D11.13", "O13351", "SPBC365.06", "Q10356", "SPAC22E12.03c", "SPAC1687.05" ] }, "reaction_10750010": { "compartment": "compartment_70101", "id": "reaction_10750010", "reactome": "R-SPO-5696600", "name": "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750001", "species_29356" ], "products": [ "species_10749260", "species_10750007" ], "modifiers": [ [ "species_10750001", "catalyst" ] ], "additional_components": [ "O94448", "SPAC1687.02", "O74442", "SPCC1682.12c", "P06652", "SPAC24H6.05", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94448", "SPAC1687.02", "O74442", "SPCC1682.12c", "P06652", "SPAC24H6.05", "O94448", "SPAC1687.02", "O74442", "SPCC1682.12c", "P06652", "SPAC24H6.05" ] }, "reaction_10734890": { "compartment": "compartment_12045", "id": "reaction_10734890", "reactome": "R-SPO-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855663", "species_449229" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10734887", "catalyst" ] ], "additional_components": [ "SPAC18B11.05" ] }, "reaction_10739496": { "compartment": "compartment_17957", "id": "reaction_10739496", "reactome": "R-SPO-446189", "name": "Addition of a second glucose to the N-glycan precursor by ALG8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449649", "species_532542" ], "products": [ "species_449311", "species_449638" ], "modifiers": [ [ "species_10739493", "catalyst" ] ], "additional_components": [ "SPAC17C9.07" ] }, "reaction_10739692": { "compartment": "compartment_70101", "id": "reaction_10739692", "reactome": "R-SPO-449734", "name": "Acetylation of glucosamine 6-phosphate to GlcNAc6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449701", "species_76183" ], "products": [ "species_76194", "species_449703" ], "modifiers": [ [ "species_10739689", "catalyst" ] ], "additional_components": [ "O13738", "SPAC16E8.03" ] }, "reaction_10734739": { "compartment": "compartment_70101", "id": "reaction_10734739", "reactome": "R-SPO-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10734735" ], "products": [ "species_10734737" ], "modifiers": [], "additional_components": [ "SPAC513.01c", "O14460", "SPAC513.01c", "species_29438" ] }, "reaction_10734850": { "compartment": "compartment_12045", "id": "reaction_10734850", "reactome": "R-SPO-162742", "name": "(ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855660" ], "products": [ "species_8855660" ], "modifiers": [ [ "species_10734847", "catalyst" ] ], "additional_components": [ "Q09782", "SPAC13G6.03", "Q9Y7P2", "SPCC1450.15" ] }, "reaction_10755240": { "compartment": "compartment_70101", "id": "reaction_10755240", "reactome": "R-SPO-8870466", "name": "RGGT:CHM binds RABs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755236", "species_10755140" ], "products": [ "species_10755238" ], "modifiers": [], "additional_components": [ "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "Q9HDY0", "SPAPB1A10.10c", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O94412", "SPCC1620.05", "species_1131164", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03", "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "O94412", "SPCC1620.05", "Q9HDY0", "SPAPB1A10.10c", "species_1131164", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P46960", "SPAC167.02", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03" ] }, "reaction_10755404": { "compartment": "compartment_70101", "id": "reaction_10755404", "reactome": "R-SPO-8870469", "name": "RGGT geranylgeranylates RAB proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755238", "species_1131164" ], "products": [ "species_111294", "species_10755401", "species_10755399" ], "modifiers": [ [ "species_10755238", "catalyst" ] ], "additional_components": [ "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "O94412", "SPCC1620.05", "Q9HDY0", "SPAPB1A10.10c", "species_1131164", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P46960", "SPAC167.02", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03", "O94412", "SPCC1620.05", "species_1131164", "P46960", "SPAC167.02", "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "Q9HDY0", "SPAPB1A10.10c", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03", "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "O94412", "SPCC1620.05", "Q9HDY0", "SPAPB1A10.10c", "species_1131164", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P46960", "SPAC167.02", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03" ] }, "reaction_10755807": { "compartment": "compartment_70101", "id": "reaction_10755807", "reactome": "R-SPO-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734704", "species_71284" ], "products": [ "species_71285", "species_10755799" ], "modifiers": [ [ "species_10755804", "catalyst" ] ], "additional_components": [ "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "SPBC839.14c" ] }, "reaction_10739597": { "compartment": "compartment_17957", "id": "reaction_10739597", "reactome": "R-SPO-446216", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449365" ], "products": [ "species_449311", "species_449371" ], "modifiers": [ [ "species_10739592", "catalyst" ] ], "additional_components": [ "SPAC1834.05" ] }, "reaction_10734683": { "compartment": "compartment_70101", "id": "reaction_10734683", "reactome": "R-SPO-156823", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734669", "species_10734679" ], "products": [ "species_10734681" ], "modifiers": [], "additional_components": [ "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "O42848", "SPAC23A1.11", "O42991", "SPBC839.13c", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O42848", "SPAC23A1.11", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O42991", "SPBC839.13c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10739605": { "compartment": "compartment_12045", "id": "reaction_10739605", "reactome": "R-SPO-446218", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449293" ], "products": [ "species_449283", "species_29420" ], "modifiers": [ [ "species_10739602", "catalyst" ] ], "additional_components": [ "SPAC23C4.14" ] }, "reaction_10739504": { "compartment": "compartment_12045", "id": "reaction_10739504", "reactome": "R-SPO-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449299", "species_162756" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10739501", "catalyst" ] ], "additional_components": [ "SPBC15D4.04" ] }, "reaction_10739556": { "compartment": "compartment_70101", "id": "reaction_10739556", "reactome": "R-SPO-446204", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532204", "species_29494" ], "products": [ "species_111294", "species_162756" ], "modifiers": [ [ "species_10739553", "catalyst" ] ], "additional_components": [ "O94617", "SPBC1289.08" ] }, "reaction_10739571": { "compartment": "compartment_12045", "id": "reaction_10739571", "reactome": "R-SPO-446207", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449222", "species_162756" ], "products": [ "species_449293", "species_110096" ], "modifiers": [ [ "species_10739568", "catalyst" ] ], "additional_components": [ "O14190", "SPAC56E4.02c", "O14199", "SPAC5D6.06c" ] }, "reaction_10755142": { "compartment": "compartment_70101", "id": "reaction_10755142", "reactome": "R-SPO-8870465", "name": "RGGT binds the RAB-binding subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755132", "species_10755138", "species_1131164" ], "products": [ "species_10755140" ], "modifiers": [], "additional_components": [ "O94412", "SPCC1620.05", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03", "O94412", "SPCC1620.05", "species_1131164", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03" ] }, "reaction_10734858": { "compartment": "compartment_12045", "id": "reaction_10734858", "reactome": "R-SPO-162797", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855656", "species_449229" ], "products": [ "species_8855664" ], "modifiers": [ [ "species_10734855", "catalyst" ] ], "additional_components": [ "SPAC4G8.12c" ] }, "reaction_10744931": { "compartment": "compartment_7660", "id": "reaction_10744931", "reactome": "R-SPO-4615872", "name": "RANBP2 SUMOylates HDAC4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744921" ], "products": [ "species_10743639", "species_10744929" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC800.03", "SPAC30D11.13", "O13351", "SPBC365.06", "P56523", "SPBC800.03", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10739538": { "compartment": "compartment_70101", "id": "reaction_10739538", "reactome": "R-SPO-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10739533", "catalyst" ] ], "additional_components": [ "SPAC1556.07" ] }, "reaction_10744981": { "compartment": "compartment_7660", "id": "reaction_10744981", "reactome": "R-SPO-4615910", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729457", "species_10743647" ], "products": [ "species_10743639", "species_10744979" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPBC16D10.09", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "Q03392", "SPBC16D10.09", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744729": { "compartment": "compartment_7660", "id": "reaction_10744729", "reactome": "R-SPO-4086083", "name": "SUMOylation of ING2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744714", "species_10743647" ], "products": [ "species_10743639", "species_10744727" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10748783": { "compartment": "compartment_7660", "id": "reaction_10748783", "reactome": "R-SPO-5690080", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10748776" ], "products": [ "species_10729044", "species_10748780" ], "modifiers": [ [ "species_10748776", "catalyst" ] ], "additional_components": [ "O74443", "SPCC1682.13", "Q9P7J7", "SPCC24B10.08c", "P04910", "SPAC19G12.06c", "O13719", "SPAC14C4.12c", "P04913", "SPCC622.09", "O60171", "SPBC21H7.02", "Q9UUK2", "SPAC1952.05", "Q09869", "SPAC12G12.05c", "Q9UUD6", "SPBC19C2.04c", "P04909", "SPCC622.08c", "Q9USU8", "SPBC28F2.10c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74443", "SPCC1682.13", "Q9P7J7", "SPCC24B10.08c", "P04910", "SPAC19G12.06c", "O13719", "SPAC14C4.12c", "P04913", "SPCC622.09", "O60171", "SPBC21H7.02", "Q9UUK2", "SPAC1952.05", "Q09869", "SPAC12G12.05c", "Q9UUD6", "SPBC19C2.04c", "P04909", "SPCC622.08c", "Q9USU8", "SPBC28F2.10c", "O74443", "SPCC1682.13", "Q9P7J7", "SPCC24B10.08c", "P04910", "SPAC19G12.06c", "O13719", "SPAC14C4.12c", "P04913", "SPCC622.09", "O60171", "SPBC21H7.02", "Q9UUK2", "SPAC1952.05", "Q09869", "SPAC12G12.05c", "Q9UUD6", "SPBC19C2.04c", "P04909", "SPCC622.08c", "Q9USU8", "SPBC28F2.10c" ] }, "reaction_10747105": { "compartment": "compartment_70101", "id": "reaction_10747105", "reactome": "R-SPO-5676966", "name": "PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5687536", "species_71284" ], "products": [ "species_71285", "species_5687529" ], "modifiers": [ [ "species_10747102", "catalyst" ] ], "additional_components": [ "SPAC869.08" ] }, "reaction_10745717": { "compartment": "compartment_70101", "id": "reaction_10745717", "reactome": "R-SPO-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745706", "species_71284" ], "products": [ "species_71285", "species_10745709" ], "modifiers": [ [ "species_10745714", "catalyst" ] ], "additional_components": [ "SPAC513.01c", "SPAC513.01c", "SPCC576.14" ] }, "reaction_10749267": { "compartment": "compartment_70101", "id": "reaction_10749267", "reactome": "R-SPO-5690152", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749262", "species_29356" ], "products": [ "species_10749264", "species_10729165" ], "modifiers": [ [ "species_10749262", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q11119", "SPBC6B1.06c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q11119", "SPBC6B1.06c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q11119", "SPBC6B1.06c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10734729": { "compartment": "compartment_70101", "id": "reaction_10734729", "reactome": "R-SPO-156913", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10734720", "species_10734724" ], "products": [ "species_10734706", "species_10734726" ], "modifiers": [ [ "species_10734720", "catalyst" ] ], "additional_components": [ "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04", "species_29420", "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "P0CT53", "SPCC794.09c", "species_29438", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "species_29420", "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04", "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04" ] }, "reaction_10745703": { "compartment": "compartment_70101", "id": "reaction_10745703", "reactome": "R-SPO-5358475", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745695", "species_113592", "species_31633" ], "products": [ "species_10734735", "species_111294", "species_76577" ], "modifiers": [ [ "species_10745700", "catalyst" ] ], "additional_components": [ "SPAC513.01c", "SPAC513.01c", "SPBC577.12" ] }, "reaction_10744614": { "compartment": "compartment_7660", "id": "reaction_10744614", "reactome": "R-SPO-3900047", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744604" ], "products": [ "species_10743639", "species_10744612" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBP8B7.16c", "SPAC30D11.13", "O13351", "SPBC365.06", "P24782", "SPBP8B7.16c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10734687": { "compartment": "compartment_70101", "id": "reaction_10734687", "reactome": "R-SPO-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732216" ], "products": [ "species_10734685", "species_10731937" ], "modifiers": [], "additional_components": [ "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "P0C016", "SPAC6G10.11c", "O42706", "SPAC959.08", "P0C8R3", "SPAC589.10c", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O14388", "SPBC685.07c", "Q09668", "SPAC11E3.15", "P52822", "SPAC3H5.12c", "P36584", "SPAPB8E5.06c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P05733", "SPCC1223.05c", "Q9P784", "SPBC1711.06", "O74864", "SPCC18.14c", "O60143", "SPBC18H10.12c", "P0CT77", "SPAC26A3.07c", "P0CT61", "SPCC1322.11", "P79015", "SPAC3H5.10", "P35679", "SPBP8B7.03c", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "O14069", "SPAC1687.06c", "Q09127", "SPBC18E5.04", "P0CT72", "SPBC839.04", "P08094", "SPBP8B7.06", "O94238", "SPAC1805.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "Q9P769", "SPAP7G5.05", "P0CT68", "SPAC3A12.10", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "Q9USR7", "SPBC577.02", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O74904", "SPCC613.05c", "O42699", "SPCC1682.14", "P40372", "SPAC17A5.03", "P0CT83", "SPCC16C4.13c", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07", "Q9US22", "SPAC1783.08c", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "P0C016", "SPAC6G10.11c", "O42706", "SPAC959.08", "P0C8R3", "SPAC589.10c", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "P79071", "SPCC622.18", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O14388", "SPBC685.07c", "Q09668", "SPAC11E3.15", "P52822", "SPAC3H5.12c", "P36584", "SPAPB8E5.06c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P05733", "SPCC1223.05c", "Q9P784", "SPBC1711.06", "O74864", "SPCC18.14c", "O60143", "SPBC18H10.12c", "P0CT77", "SPAC26A3.07c", "P0CT61", "SPCC1322.11", "P79015", "SPAC3H5.10", "P35679", "SPBP8B7.03c", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "O14069", "SPAC1687.06c", "Q09127", "SPBC18E5.04", "P0CT72", "SPBC839.04", "P08094", "SPBP8B7.06", "O94238", "SPAC1805.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "Q9P769", "SPAP7G5.05", "P0CT68", "SPAC3A12.10", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "Q9USR7", "SPBC577.02", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O74904", "SPCC613.05c", "O42699", "SPCC1682.14", "P40372", "SPAC17A5.03", "P0CT83", "SPCC16C4.13c", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07", "Q9US22", "SPAC1783.08c", "O42848", "SPAC23A1.11", "O42991", "SPBC839.13c" ] }, "reaction_10750104": { "compartment": "compartment_70101", "id": "reaction_10750104", "reactome": "R-SPO-6781779", "name": "USP13 deubiquitinates BECN1,USP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750099", "species_29356" ], "products": [ "species_10735397", "species_10750101" ], "modifiers": [ [ "species_10750099", "catalyst" ] ], "additional_components": [ "Q11119", "SPBC6B1.06c", "P87117", "SPAC20G8.10c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q11119", "SPBC6B1.06c", "P87117", "SPAC20G8.10c", "Q11119", "SPBC6B1.06c", "P87117", "SPAC20G8.10c" ] }, "reaction_10734783": { "compartment": "compartment_17957", "id": "reaction_10734783", "reactome": "R-SPO-162683", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_8855661" ], "products": [ "species_76194", "species_8855666" ], "modifiers": [ [ "species_10734780", "catalyst" ] ], "additional_components": [ "SPAC144.10c" ] }, "reaction_10744969": { "compartment": "compartment_7660", "id": "reaction_10744969", "reactome": "R-SPO-4615889", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10741535" ], "products": [ "species_10743639", "species_10744967" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC36.05c", "SPAC30D11.13", "O59702", "SPBC36.05c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10747799": { "compartment": "compartment_70101", "id": "reaction_10747799", "reactome": "R-SPO-5689539", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747795", "species_10746685" ], "products": [ "species_10747797" ], "modifiers": [], "additional_components": [ "SPAC6G9.08", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13", "Q92353", "SPAC6G9.08", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10745017": { "compartment": "compartment_7660", "id": "reaction_10745017", "reactome": "R-SPO-4641345", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10745008" ], "products": [ "species_10743639", "species_10745015" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC1A4.03c", "SPAC30D11.13", "P08096", "SPBC1A4.03c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10749279": { "compartment": "compartment_7660", "id": "reaction_10749279", "reactome": "R-SPO-5690157", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10749274" ], "products": [ "species_10729044", "species_10749276" ], "modifiers": [ [ "species_10749274", "catalyst" ] ], "additional_components": [ "P04910", "SPAC19G12.06c", "Q9P7S5", "SPAC23G3.08c", "P04909", "SPCC622.08c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P04910", "SPAC19G12.06c", "Q9P7S5", "SPAC23G3.08c", "P04909", "SPCC622.08c", "P04910", "SPAC19G12.06c", "Q9P7S5", "SPAC23G3.08c", "P04909", "SPCC622.08c" ] }, "reaction_10755134": { "compartment": "compartment_70101", "id": "reaction_10755134", "reactome": "R-SPO-8870461", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755130", "species_10755128" ], "products": [ "species_10755132" ], "modifiers": [], "additional_components": [ "SPAC167.02", "SPCC1620.05", "O94412", "SPCC1620.05", "P46960", "SPAC167.02" ] }, "reaction_10739595": { "compartment": "compartment_17957", "id": "reaction_10739595", "reactome": "R-SPO-446215", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449315", "species_449229" ], "products": [ "species_449311", "species_449312" ], "modifiers": [ [ "species_10739592", "catalyst" ] ], "additional_components": [ "SPAC1834.05" ] }, "reaction_10755762": { "compartment": "compartment_7660", "id": "reaction_10755762", "reactome": "R-SPO-8932221", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10731070" ], "products": [ "species_10755754", "species_77502" ], "modifiers": [ [ "species_10755759", "catalyst" ] ], "additional_components": [ "SPAC13G7.02c", "SPAC13G7.02c", "SPAC23C4.06c" ] }, "reaction_10739579": { "compartment": "compartment_12045", "id": "reaction_10739579", "reactome": "R-SPO-446208", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449283" ], "products": [ "species_449737", "species_29420" ], "modifiers": [ [ "species_10739576", "catalyst" ] ], "additional_components": [ "SPBC11B10.01" ] }, "reaction_10739682": { "compartment": "compartment_70101", "id": "reaction_10739682", "reactome": "R-SPO-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29512" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10739679", "catalyst" ] ], "additional_components": [ "Q09740", "SPBC12C2.11" ] }, "reaction_10744836": { "compartment": "compartment_13231", "id": "reaction_10744836", "reactome": "R-SPO-4551649", "name": "RANBP2 SUMOylates RANBP2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744823", "species_10743647" ], "products": [ "species_10744833", "species_10743639" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1773.07c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O13351", "SPBC365.06", "Q09717", "SPBC1773.07c", "SPAC30D11.13", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10739480": { "compartment": "compartment_70101", "id": "reaction_10739480", "reactome": "R-SPO-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10739477", "catalyst" ] ], "additional_components": [ "SPAC13C5.05c" ] }, "reaction_10738916": { "compartment": "compartment_70101", "id": "reaction_10738916", "reactome": "R-SPO-426520", "name": "Endonucleolytic RISC hydrolyzes target RNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426523" ], "products": [ "species_426511" ], "modifiers": [ [ "species_10738891", "catalyst" ] ], "additional_components": [ "O74957", "SPCC736.11" ] }, "reaction_10745975": { "compartment": "compartment_70101", "id": "reaction_10745975", "reactome": "R-SPO-5578744", "name": "Importin-8 imports AGO2:miRNA into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745968", "species_10745948" ], "products": [ "species_10745956", "species_10745972" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "P28748", "SPBC1289.03c", "species_29438", "O59809", "SPCC550.11", "O74957", "SPCC736.11", "O74957", "SPCC736.11", "O59809", "SPCC550.11", "P28748", "SPBC1289.03c", "species_29438", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10745966": { "compartment": "compartment_7660", "id": "reaction_10745966", "reactome": "R-SPO-5578742", "name": "AGO1,2:small RNA complexes interact with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745962", "species_10730706", "species_10737547" ], "products": [ "species_10745964" ], "modifiers": [], "additional_components": [ "O74957", "SPCC736.11", "Q02061", "SPAC23G3.01", "P36594", "SPBC28F2.12", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O13877", "SPAC1B3.12c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O14459", "SPACUNK4.06c", "O74825", "SPBC337.14", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "Q02061", "SPAC23G3.01", "P09322", "SPAC1834.03c", "P36595", "SPCC1020.04c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "O74957", "SPCC736.11", "P04909", "SPCC622.08c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P48003", "SPBC11B10.10c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10757019": { "compartment": "compartment_70101", "id": "reaction_10757019", "reactome": "R-SPO-9023909", "name": "C3PO hydrolyzes cleaved passenger strand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757004" ], "products": [ "species_10738889" ], "modifiers": [ [ "species_10757016", "catalyst" ] ], "additional_components": [ "O74957", "SPCC736.11", "O74957", "SPCC736.11", "O74955", "SPCC736.09c", "Q9P7V3", "SPAC30.03c" ] }, "reaction_10745950": { "compartment": "compartment_70101", "id": "reaction_10745950", "reactome": "R-SPO-5578712", "name": "Importin-8 binds AGO2:miRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738887", "species_10745946" ], "products": [ "species_10745948" ], "modifiers": [], "additional_components": [ "O74957", "SPCC736.11", "SPCC550.11", "O59809", "SPCC550.11", "O74957", "SPCC736.11" ] }, "reaction_10757024": { "compartment": "compartment_70101", "id": "reaction_10757024", "reactome": "R-SPO-9023912", "name": "AGO2 cleaves passenger strand of duplex siRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757021" ], "products": [ "species_10757004" ], "modifiers": [ [ "species_10757021", "catalyst" ] ], "additional_components": [ "O74957", "SPCC736.11", "O74957", "SPCC736.11", "O74957", "SPCC736.11" ] }, "reaction_10732342": { "compartment": "compartment_70101", "id": "reaction_10732342", "reactome": "R-SPO-73608", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500829", "species_29356" ], "products": [ "species_31633", "species_500430" ], "modifiers": [ [ "species_10732339", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:15698", "CHEBI:16704", "CHEBI:16450", "Q09190", "SPAC1556.04c", "species_442320" ] }, "reaction_10756398": { "compartment": "compartment_70101", "id": "reaction_10756398", "reactome": "R-SPO-8954327", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10756395", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_418075", "SPCC162.11c" ] }, "reaction_10750462": { "compartment": "compartment_70101", "id": "reaction_10750462", "reactome": "R-SPO-6788295", "name": "HDHD1:Mg2+ dephosphorylates PURIDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788291", "species_29356" ], "products": [ "species_29372", "species_6788290" ], "modifiers": [ [ "species_10750459", "catalyst" ] ], "additional_components": [ "O59760", "SPCC1020.07", "species_29926" ] }, "reaction_10736241": { "compartment": "compartment_70101", "id": "reaction_10736241", "reactome": "R-SPO-193052", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196344" ], "products": [ "species_193055" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10736360": { "compartment": "compartment_70101", "id": "reaction_10736360", "reactome": "R-SPO-196350", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196344" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10746449": { "compartment": "compartment_70101", "id": "reaction_10746449", "reactome": "R-SPO-5652195", "name": "SORD oxidizes D-sorbitol to Fru", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_5652213" ], "products": [ "species_70106", "species_73473", "species_29532" ], "modifiers": [ [ "species_10746446", "catalyst" ] ], "additional_components": [ "species_442320", "P36624", "SPBC1773.05c" ] }, "reaction_10746437": { "compartment": "compartment_70101", "id": "reaction_10746437", "reactome": "R-SPO-5652172", "name": "AKR1B1 reduces Glc to D-sorbitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_70113" ], "products": [ "species_29366", "species_5652213" ], "modifiers": [ [ "species_10736354", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10729667": { "compartment": "compartment_70101", "id": "reaction_10729667", "reactome": "R-SPO-70349", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_30393" ], "products": [ "species_29370", "species_29578" ], "modifiers": [ [ "species_10729664", "catalyst" ] ], "additional_components": [ "O74215", "SPAC977.16c", "species_29926" ] }, "reaction_10753479": { "compartment": "compartment_70101", "id": "reaction_10753479", "reactome": "R-SPO-6813749", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30393", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_6799497" ], "modifiers": [ [ "species_10730487", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10745910": { "compartment": "compartment_7660", "id": "reaction_10745910", "reactome": "R-SPO-5423117", "name": "PHF8 demethylates MeK21-histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10743010" ], "products": [ "species_10732874", "species_159942", "species_159939", "species_29478" ], "modifiers": [ [ "species_10743019", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPCC622.16c" ] }, "reaction_10755942": { "compartment": "compartment_70101", "id": "reaction_10755942", "reactome": "R-SPO-8941895", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733280", "species_10755938" ], "products": [ "species_10755940" ], "modifiers": [], "additional_components": [ "SPBC11B10.09", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10758108": { "compartment": "compartment_7660", "id": "reaction_10758108", "reactome": "R-SPO-9754129", "name": "CDK6 inhibitors bind CDK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9754132", "species_10756021" ], "products": [ "species_10758106" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10426", "P10815", "SPBC582.03", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "LigandDisplayForward?ligandId=7934" ] }, "reaction_10756036": { "compartment": "compartment_7660", "id": "reaction_10756036", "reactome": "R-SPO-8942836", "name": "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10756008" ], "products": [ "species_113582", "species_10756034" ], "modifiers": [ [ "species_10732457", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07" ] }, "reaction_10758118": { "compartment": "compartment_7660", "id": "reaction_10758118", "reactome": "R-SPO-9754130", "name": "CDK4 inhibitors bind CDK4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756032", "species_9754127" ], "products": [ "species_10758116" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "LigandDisplayForward?ligandId=7938", "LigandDisplayForward?ligandId=5950", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "pubchem.compound:9933545", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5680", "LigandDisplayForward?ligandId=7938", "LigandDisplayForward?ligandId=5950", "P36630", "SPAPB2B4.03", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "P10815", "SPBC582.03", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "P04551", "SPBC11B10.09", "pubchem.compound:9933545", "P25009", "SPBC19F5.01c", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5680" ] }, "reaction_10756010": { "compartment": "compartment_13231", "id": "reaction_10756010", "reactome": "R-SPO-8942803", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755982" ], "products": [ "species_10756008" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10733308": { "compartment": "compartment_70101", "id": "reaction_10733308", "reactome": "R-SPO-75849", "name": "Transport of Citrate from Mitochondrial Matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29654", "species_198498" ], "products": [ "species_76190", "species_113544" ], "modifiers": [ [ "species_10733305", "catalyst" ] ], "additional_components": [ "SPAC19G12.05" ] }, "reaction_10733300": { "compartment": "compartment_70101", "id": "reaction_10733300", "reactome": "R-SPO-75848", "name": "ACLY tetramer transforms CIT to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_76190", "species_113592" ], "products": [ "species_29370", "species_76213", "species_29372", "species_76183" ], "modifiers": [ [ "species_10733297", "catalyst" ] ], "additional_components": [ "O13907", "SPAC22A12.16" ] }, "reaction_10736846": { "compartment": "compartment_70101", "id": "reaction_10736846", "reactome": "R-SPO-200555", "name": "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10733319", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "SPAC56E4.04c" ] }, "reaction_10752466": { "compartment": "compartment_70101", "id": "reaction_10752466", "reactome": "R-SPO-6801109", "name": "CHM binds RGGT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752455", "species_10752462" ], "products": [ "species_10752464" ], "modifiers": [], "additional_components": [ "O94412", "SPCC1620.05", "P46960", "SPAC167.02", "SPBC15C4.03", "O94412", "SPCC1620.05", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03" ] }, "reaction_10752457": { "compartment": "compartment_876", "id": "reaction_10752457", "reactome": "R-SPO-6801101", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752448", "species_10752453" ], "products": [ "species_10752455" ], "modifiers": [], "additional_components": [ "SPCC1620.05", "SPAC167.02", "O94412", "SPCC1620.05", "P46960", "SPAC167.02" ] }, "reaction_10746376": { "compartment": "compartment_7660", "id": "reaction_10746376", "reactome": "R-SPO-5651654", "name": "SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10743010" ], "products": [ "species_10746366", "species_77502" ], "modifiers": [ [ "species_10746371", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPCC4B3.12" ] }, "reaction_10746381": { "compartment": "compartment_7660", "id": "reaction_10746381", "reactome": "R-SPO-5651657", "name": "SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746366", "species_77087" ], "products": [ "species_10746379", "species_77502" ], "modifiers": [ [ "species_10746371", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPCC4B3.12" ] }, "reaction_10745162": { "compartment": "compartment_7660", "id": "reaction_10745162", "reactome": "R-SPO-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732874", "species_77087" ], "products": [ "species_10745159", "species_77502" ], "modifiers": [ [ "species_10743825", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPAC890.07c" ] }, "reaction_10746660": { "compartment": "compartment_7660", "id": "reaction_10746660", "reactome": "R-SPO-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745159", "species_77087" ], "products": [ "species_10746658", "species_77502" ], "modifiers": [ [ "species_10743825", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPAC890.07c" ] }, "reaction_10743853": { "compartment": "compartment_7660", "id": "reaction_10743853", "reactome": "R-SPO-3215385", "name": "CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743844" ], "products": [ "species_10743850" ], "modifiers": [ [ "species_10743844", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P78963", "SPBC16H5.11c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P78963", "SPBC16H5.11c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P78963", "SPBC16H5.11c" ] }, "reaction_10745307": { "compartment": "compartment_7660", "id": "reaction_10745307", "reactome": "R-SPO-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10745271" ], "products": [ "species_77502", "species_10745305" ], "modifiers": [ [ "species_10743825", "catalyst" ] ], "additional_components": [ "P04910", "SPAC19G12.06c", "P04909", "SPCC622.08c", "P04910", "SPAC19G12.06c", "P04909", "SPCC622.08c", "SPAC890.07c" ] }, "reaction_10737810": { "compartment": "compartment_70101", "id": "reaction_10737810", "reactome": "R-SPO-350600", "name": "Antizyme inhibitor binds to OAZ and stablizes ODC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737804", "species_10737795" ], "products": [ "species_10737808" ], "modifiers": [], "additional_components": [ "SPAC144.04c", "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c", "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c" ] }, "reaction_10737980": { "compartment": "compartment_70101", "id": "reaction_10737980", "reactome": "R-SPO-353125", "name": "26S proteosome degrades ODC holoenzyme complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737795" ], "products": [ "species_10737789" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c", "SPBC577.14c", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10737797": { "compartment": "compartment_70101", "id": "reaction_10737797", "reactome": "R-SPO-350567", "name": "Antizyme OAZ binds to Ornithine decarboxylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10730038", "species_10737789" ], "products": [ "species_10737795" ], "modifiers": [], "additional_components": [ "SPAC144.04c", "SPBC577.14c", "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c" ] }, "reaction_10752439": { "compartment": "compartment_7660", "id": "reaction_10752439", "reactome": "R-SPO-6800490", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10752434" ], "products": [ "species_113582", "species_10752437" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "SPBC19C7.03", "SPBC19C7.03", "SPCC23B6.03c" ] }, "reaction_10752490": { "compartment": "compartment_17906", "id": "reaction_10752490", "reactome": "R-SPO-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10752485", "catalyst" ] ], "additional_components": [ "Q96VG1", "SPBC119.18", "O59707", "SPBC36.10", "Q9UT07", "SPAP8A3.10" ] }, "reaction_10752443": { "compartment": "compartment_70101", "id": "reaction_10752443", "reactome": "R-SPO-6800793", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752437" ], "products": [ "species_10752441" ], "modifiers": [], "additional_components": [ "SPBC19C7.03", "SPBC19C7.03" ] }, "reaction_10752487": { "compartment": "compartment_17927", "id": "reaction_10752487", "reactome": "R-SPO-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752471", "species_10752483" ], "products": [ "species_10752485" ], "modifiers": [], "additional_components": [ "SPBC119.18", "O59707", "SPBC36.10", "Q9UT07", "SPAP8A3.10", "Q96VG1", "SPBC119.18", "O59707", "SPBC36.10", "Q9UT07", "SPAP8A3.10" ] }, "reaction_10746130": { "compartment": "compartment_70101", "id": "reaction_10746130", "reactome": "R-SPO-5618331", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_10746127" ], "products": [ "species_10738115", "species_76183" ], "modifiers": [ [ "species_10745603", "catalyst" ] ], "additional_components": [ "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "SPBC800.03" ] }, "reaction_10743065": { "compartment": "compartment_20699", "id": "reaction_10743065", "reactome": "R-SPO-2214351", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10743057" ], "products": [ "species_29370", "species_10743062" ], "modifiers": [ [ "species_10743057", "catalyst" ] ], "additional_components": [ "Q10149", "SPAC1D4.02c", "P11620", "SPBC1703.10", "P50528", "SPAC23C11.16", "species_29438", "Q10149", "SPAC1D4.02c", "P11620", "SPBC1703.10", "P50528", "SPAC23C11.16", "species_29438", "Q10149", "SPAC1D4.02c", "P11620", "SPBC1703.10", "P50528", "SPAC23C11.16", "species_29438" ] }, "reaction_10757878": { "compartment": "compartment_17906", "id": "reaction_10757878", "reactome": "R-SPO-9693214", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756754", "species_10757872" ], "products": [ "species_10757876" ], "modifiers": [], "additional_components": [ "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q10056", "SPAC1F5.09c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "P50527", "SPBC1604.14c" ] }, "reaction_10746782": { "compartment": "compartment_70101", "id": "reaction_10746782", "reactome": "R-SPO-5668932", "name": "PAK2 phosphorylates myosin regulatory light chain (MRLC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746773" ], "products": [ "species_29370", "species_10746779" ], "modifiers": [ [ "species_10746316", "catalyst" ] ], "additional_components": [ "Q9USI6", "SPCC645.05c", "Q09196", "SPAP8A3.08", "Q9UUG5", "SPAC926.03", "O14157", "SPAC4A8.05c", "Q9USI6", "SPCC645.05c", "Q09196", "SPAP8A3.08", "Q9UUG5", "SPAC926.03", "O14157", "SPAC4A8.05c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c" ] }, "reaction_10756841": { "compartment": "compartment_876", "id": "reaction_10756841", "reactome": "R-SPO-9013437", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831", "species_29356" ], "products": [ "species_10756817", "species_29372" ], "modifiers": [ [ "species_10756838", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757894": { "compartment": "compartment_876", "id": "reaction_10757894", "reactome": "R-SPO-9693243", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831" ], "products": [ "species_10757892" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10756608": { "compartment": "compartment_7660", "id": "reaction_10756608", "reactome": "R-SPO-9009533", "name": "TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732619", "species_10732432", "species_10756604" ], "products": [ "species_10756606" ], "modifiers": [], "additional_components": [ "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "SPAC3A11.12c", "O43058", "SPBC4C3.12", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "P24782", "SPBP8B7.16c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "CHEBI:27974", "species_193066", "Q9USU9", "SPBC28F2.09", "O43058", "SPBC4C3.12", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "P17871", "SPAC3A11.12c", "species_193132", "P24782", "SPBP8B7.16c", "O74948", "SPCC553.11c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "CHEBI:27974", "species_193066" ] }, "reaction_10756525": { "compartment": "compartment_70101", "id": "reaction_10756525", "reactome": "R-SPO-8981931", "name": "RAC1 and CDC42 activate PAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738343", "species_10738231" ], "products": [ "species_10746302", "species_10738341" ], "modifiers": [], "additional_components": [ "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c" ] }, "reaction_10746286": { "compartment": "compartment_70101", "id": "reaction_10746286", "reactome": "R-SPO-5626469", "name": "GTP-bound RAC1 and CDC42 bind IQGAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746282", "species_10738231" ], "products": [ "species_10746284" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "O14188", "SPAC4F8.13c", "Q01112", "SPAC110.03", "species_29438", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "O14188", "SPAC4F8.13c", "species_29438" ] }, "reaction_10757002": { "compartment": "compartment_7660", "id": "reaction_10757002", "reactome": "R-SPO-9023861", "name": "PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756606", "species_10743825" ], "products": [ "species_10756994" ], "modifiers": [], "additional_components": [ "Q9USU9", "SPBC28F2.09", "O43058", "SPBC4C3.12", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "P17871", "SPAC3A11.12c", "species_193132", "P24782", "SPBP8B7.16c", "O74948", "SPCC553.11c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "CHEBI:27974", "species_193066", "SPAC890.07c", "O43058", "SPBC4C3.12", "P17871", "SPAC3A11.12c", "P24782", "SPBP8B7.16c", "Q9URX7", "SPAC890.07c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "Q9USU9", "SPBC28F2.09", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "O74948", "SPCC553.11c", "CHEBI:27974", "species_193066" ] }, "reaction_10746295": { "compartment": "compartment_876", "id": "reaction_10746295", "reactome": "R-SPO-5626549", "name": "IQGAPs bind CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746284", "species_10737009" ], "products": [ "species_10746290" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "O14188", "SPAC4F8.13c", "species_29438", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "P05933", "SPAC3A12.14", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "species_74016", "O14188", "SPAC4F8.13c", "O14008", "SPAC29A4.05", "species_29438" ] }, "reaction_10756782": { "compartment": "compartment_876", "id": "reaction_10756782", "reactome": "R-SPO-9013158", "name": "CDC42 GDIs block activation of CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756776", "species_10756778" ], "products": [ "species_10756780" ], "modifiers": [], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "O14224", "SPAC6F12.06", "species_29420", "Q01112", "SPAC110.03", "O14224", "SPAC6F12.06" ] }, "reaction_10758013": { "compartment": "compartment_876", "id": "reaction_10758013", "reactome": "R-SPO-9726862", "name": "Phosphorylated RHOU translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758007" ], "products": [ "species_10758011" ], "modifiers": [], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "species_29420", "Q01112", "SPAC110.03" ] }, "reaction_10756867": { "compartment": "compartment_876", "id": "reaction_10756867", "reactome": "R-SPO-9013438", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756855", "species_10756863" ], "products": [ "species_10756865" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "O13995", "SPAC25B8.01", "Q09195", "SPBC16G5.18", "Q10311", "SPAC6C3.08", "O13995", "SPAC25B8.01", "Q09195", "SPBC16G5.18", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "Q10311", "SPAC6C3.08", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10757000": { "compartment": "compartment_7660", "id": "reaction_10757000", "reactome": "R-SPO-9023860", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756996", "species_10756988" ], "products": [ "species_10756998" ], "modifiers": [], "additional_components": [ "O43058", "SPBC4C3.12", "P17871", "SPAC3A11.12c", "P24782", "SPBP8B7.16c", "Q9URX7", "SPAC890.07c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "Q9USU9", "SPBC28F2.09", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "O74948", "SPCC553.11c", "CHEBI:27974", "species_193066", "Q10325", "SPAC17G8.13c", "Q9UUK2", "SPAC1952.05", "O43058", "SPBC4C3.12", "Q10325", "SPAC17G8.13c", "P17871", "SPAC3A11.12c", "P24782", "SPBP8B7.16c", "Q9URX7", "SPAC890.07c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "Q9USU9", "SPBC28F2.09", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "O74948", "SPCC553.11c", "Q9UUK2", "SPAC1952.05", "CHEBI:27974", "species_193066" ] }, "reaction_10756484": { "compartment": "compartment_70101", "id": "reaction_10756484", "reactome": "R-SPO-8980691", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10734490" ], "products": [ "species_10734492", "species_29420" ], "modifiers": [ [ "species_10738645", "catalyst" ] ], "additional_components": [ "species_29420", "Q09914", "SPAC1F7.04", "Q09914", "SPAC1F7.04", "species_29438", "Q9USU1", "SPBC336.03", "P26674", "SPCC1442.01" ] }, "reaction_10746292": { "compartment": "compartment_70101", "id": "reaction_10746292", "reactome": "R-SPO-5626507", "name": "IQGAPs bind F-actin, which is inhibited by calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746284", "species_10742720" ], "products": [ "species_10746288" ], "modifiers": [ [ "species_10746290", "inhibitor" ] ], "additional_components": [ "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "O14188", "SPAC4F8.13c", "species_29438", "species_113592", "O60054", "SPBC56F2.03", "P10989", "SPBC32H8.12c", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "species_113592", "O60054", "SPBC56F2.03", "O14188", "SPAC4F8.13c", "P10989", "SPBC32H8.12c", "species_29438", "P05933", "SPAC3A12.14", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "species_74016", "O14188", "SPAC4F8.13c", "O14008", "SPAC29A4.05", "species_29438" ] }, "reaction_10756869": { "compartment": "compartment_876", "id": "reaction_10756869", "reactome": "R-SPO-9013452", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831" ], "products": [ "species_10756855" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10756701": { "compartment": "compartment_876", "id": "reaction_10756701", "reactome": "R-SPO-9013009", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734492", "species_10756697" ], "products": [ "species_10756699" ], "modifiers": [], "additional_components": [ "Q09914", "SPAC1F7.04", "species_29438", "O74534", "SPCC74.01", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O43027", "SPBC354.13", "O74498", "SPCC285.11", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "P36583", "SPBC12D12.04c", "O14188", "SPAC4F8.13c", "O74786", "SPBC26H8.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c", "O74534", "SPCC74.01", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O43027", "SPBC354.13", "species_29438", "O74498", "SPCC285.11", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "P36583", "SPBC12D12.04c", "O14188", "SPAC4F8.13c", "O74786", "SPBC26H8.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c" ] }, "reaction_10757843": { "compartment": "compartment_876", "id": "reaction_10757843", "reactome": "R-SPO-9692800", "name": "CDC42 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738231" ], "products": [ "species_10757841" ], "modifiers": [], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "Q01112", "SPAC110.03", "species_29438" ] }, "reaction_10756625": { "compartment": "compartment_7660", "id": "reaction_10756625", "reactome": "R-SPO-9011949", "name": "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756620" ], "products": [ "species_10747338", "species_10756622" ], "modifiers": [ [ "species_10756620", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "O94691", "SPBC83.07", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "CHEBI:50114", "SPBC83.07", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "CHEBI:50114", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "O94691", "SPBC83.07", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "CHEBI:50114" ] }, "reaction_10756686": { "compartment": "compartment_876", "id": "reaction_10756686", "reactome": "R-SPO-9013006", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734492" ], "products": [ "species_10756684" ], "modifiers": [], "additional_components": [ "Q09914", "SPAC1F7.04", "species_29438", "Q09914", "SPAC1F7.04", "species_29438" ] }, "reaction_10756523": { "compartment": "compartment_70101", "id": "reaction_10756523", "reactome": "R-SPO-8981926", "name": "RAC1 and CDC42 activate PAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738231", "species_10738347" ], "products": [ "species_10746304", "species_10738345" ], "modifiers": [], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "SPBC1604.14c" ] }, "reaction_10756658": { "compartment": "compartment_7660", "id": "reaction_10756658", "reactome": "R-SPO-9012319", "name": "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10756653" ], "products": [ "species_113582", "species_10756655" ], "modifiers": [ [ "species_10756653", "catalyst" ] ], "additional_components": [ "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O14098", "SPAC2F3.15", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "CHEBI:50114", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O59748", "SPBC530.13", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O14098", "SPAC2F3.15", "O13877", "SPAC1B3.12c", "CHEBI:50114", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O59748", "SPBC530.13", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O14098", "SPAC2F3.15", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "CHEBI:50114", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O59748", "SPBC530.13", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10756519": { "compartment": "compartment_70101", "id": "reaction_10756519", "reactome": "R-SPO-8981637", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734492", "species_29356" ], "products": [ "species_29372", "species_10734490" ], "modifiers": [ [ "species_10756516", "catalyst" ] ], "additional_components": [ "Q09914", "SPAC1F7.04", "species_29438", "species_29420", "Q09914", "SPAC1F7.04", "O74335", "SPBC17F3.01c", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757377": { "compartment": "compartment_70101", "id": "reaction_10757377", "reactome": "R-SPO-9626816", "name": "PIN1 binds p-S345-NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757370", "species_10757372" ], "products": [ "species_10757374" ], "modifiers": [ [ "species_10757372", "catalyst" ] ], "additional_components": [ "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "SPCC16C4.03", "O74448", "SPCC16C4.03", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "SPCC16C4.03" ] }, "reaction_10746044": { "compartment": "compartment_5263232", "id": "reaction_10746044", "reactome": "R-SPO-5610749", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10746040" ], "products": [ "species_10746034", "species_10746042" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "P40376", "SPBC106.10", "SPBC106.10", "P36600", "SPAC8C9.03", "species_30389" ] }, "reaction_10756834": { "compartment": "compartment_876", "id": "reaction_10756834", "reactome": "R-SPO-9013435", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756817" ], "products": [ "species_10756831", "species_29420" ], "modifiers": [ [ "species_10756817", "catalyst" ] ], "additional_components": [ "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01" ] }, "reaction_10756918": { "compartment": "compartment_876", "id": "reaction_10756918", "reactome": "R-SPO-9018768", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756915" ], "products": [ "species_10756895", "species_29420" ], "modifiers": [ [ "species_10756915", "catalyst" ] ], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "Q01112", "SPAC110.03", "species_29438", "species_29420", "Q01112", "SPAC110.03" ] }, "reaction_10756793": { "compartment": "compartment_876", "id": "reaction_10756793", "reactome": "R-SPO-9013159", "name": "CDC42 GEFs activate CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756776" ], "products": [ "species_29420", "species_10738231" ], "modifiers": [ [ "species_10756790", "catalyst" ] ], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "Q01112", "SPAC110.03", "species_29438", "Q09763", "SPAC24H6.09", "O59679", "SPBC29A3.17", "Q9USU1", "SPBC336.03", "Q9HGL2", "SPBC800.10c", "P26674", "SPCC1442.01", "Q04665", "SPAC23H3.13c" ] }, "reaction_10745852": { "compartment": "compartment_12045", "id": "reaction_10745852", "reactome": "R-SPO-5362412", "name": "SYVN1 ubiquitinates Hh C-terminal fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745845", "species_10729165" ], "products": [ "species_10745849" ], "modifiers": [ [ "species_10745845", "catalyst" ] ], "additional_components": [ "O13875", "SPAC1B3.10c", "Q9UTC8", "SPAC227.11c", "Q9P3A7", "SPAC1565.08", "O74757", "SPBC17D11.02c", "O94458", "SPAC1687.17c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9UTC8", "SPAC227.11c", "O13875", "SPAC1B3.10c", "Q9P3A7", "SPAC1565.08", "O74757", "SPBC17D11.02c", "O94458", "SPAC1687.17c", "O13875", "SPAC1B3.10c", "Q9UTC8", "SPAC227.11c", "Q9P3A7", "SPAC1565.08", "O74757", "SPBC17D11.02c", "O94458", "SPAC1687.17c" ] }, "reaction_10756682": { "compartment": "compartment_70101", "id": "reaction_10756682", "reactome": "R-SPO-9012835", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756678", "species_10734490" ], "products": [ "species_10756680" ], "modifiers": [], "additional_components": [ "O14224", "SPAC6F12.06", "species_29420", "Q09914", "SPAC1F7.04", "species_29420", "Q09914", "SPAC1F7.04", "O14224", "SPAC6F12.06" ] }, "reaction_10757858": { "compartment": "compartment_70101", "id": "reaction_10757858", "reactome": "R-SPO-9693198", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831", "species_10757854" ], "products": [ "species_10757856" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "O94655", "SPBC405.04c", "Q9HGP5", "SPAC631.01c", "Q10056", "SPAC1F5.09c", "O13728", "SPAC15A10.08", "Q92356", "SPAC6G9.11", "Q9P7E8", "SPAPJ760.02c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c", "Q7LKY2", "SPBC1289.14", "P50527", "SPBC1604.14c", "O13728", "SPAC15A10.08", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "O43027", "SPBC354.13", "Q10133", "SPAC16.01", "species_29438", "Q9P3B1", "SPAC1565.02c", "Q7LKY2", "SPBC1289.14", "P50527", "SPBC1604.14c", "O94655", "SPBC405.04c", "Q9HGP5", "SPAC631.01c", "Q10056", "SPAC1F5.09c", "Q9HE04", "SPAC20H4.11c", "O13928", "SPAC23C4.08", "Q9P7E8", "SPAPJ760.02c", "Q874R1", "SPAC16A10.04" ] }, "reaction_10751276": { "compartment": "compartment_1222693", "id": "reaction_10751276", "reactome": "R-SPO-6798174", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524165" ], "products": [ "species_29370", "species_1629751" ], "modifiers": [ [ "species_10751273", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05" ] }, "reaction_10756913": { "compartment": "compartment_876", "id": "reaction_10756913", "reactome": "R-SPO-9018766", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756895", "species_10756909" ], "products": [ "species_10756911" ], "modifiers": [], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "Q9USZ0", "SPBC1306.02", "O74749", "SPBC1734.08", "Q9USR1", "SPBC577.08c", "O13728", "SPAC15A10.08", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "Q92462", "SPAC11G7.02", "O94478", "SPCC1919.11", "P50527", "SPBC1604.14c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "Q9UTG2", "SPAC1805.15c", "O14188", "SPAC4F8.13c", "O94685", "SPBC83.01", "O14326", "SPBC16E9.11c", "Q9USZ0", "SPBC1306.02", "O74749", "SPBC1734.08", "Q9USR1", "SPBC577.08c", "O13728", "SPAC15A10.08", "Q9HGL2", "SPBC800.10c", "species_29438", "Q10172", "SPAC25G10.09c", "Q92462", "SPAC11G7.02", "O94478", "SPCC1919.11", "P50527", "SPBC1604.14c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "Q9UTG2", "SPAC1805.15c", "O14188", "SPAC4F8.13c", "O94685", "SPBC83.01", "O14326", "SPBC16E9.11c" ] }, "reaction_10757398": { "compartment": "compartment_70101", "id": "reaction_10757398", "reactome": "R-SPO-9626880", "name": "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757392", "species_113592" ], "products": [ "species_29370", "species_10757370" ], "modifiers": [ [ "species_10739926", "catalyst" ] ], "additional_components": [ "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "SPAC24B11.06c" ] }, "reaction_10756800": { "compartment": "compartment_876", "id": "reaction_10756800", "reactome": "R-SPO-9013161", "name": "CDC42 GAPs stimulate CDC42 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10738231" ], "products": [ "species_10756776", "species_29372" ], "modifiers": [ [ "species_10756797", "catalyst" ] ], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "species_29420", "Q01112", "SPAC110.03", "O74335", "SPBC17F3.01c", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757395": { "compartment": "compartment_70101", "id": "reaction_10757395", "reactome": "R-SPO-9626832", "name": "MAPK1 or MAPK3 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757392", "species_113592" ], "products": [ "species_29370", "species_10757370" ], "modifiers": [ [ "species_10744304", "catalyst" ] ], "additional_components": [ "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10757874": { "compartment": "compartment_876", "id": "reaction_10757874", "reactome": "R-SPO-9693207", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831" ], "products": [ "species_10757872" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10757388": { "compartment": "compartment_70101", "id": "reaction_10757388", "reactome": "R-SPO-9626817", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10757374" ], "products": [ "species_29370", "species_10757386" ], "modifiers": [ [ "species_10745378", "catalyst" ] ], "additional_components": [ "O74448", "SPCC16C4.03", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "O74448", "SPCC16C4.03", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10749638": { "compartment": "compartment_12045", "id": "reaction_10749638", "reactome": "R-SPO-5693761", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_428256" ], "products": [ "species_5693768", "species_29356" ], "modifiers": [ [ "species_10749635", "catalyst" ] ], "additional_components": [ "SPAC19G12.08" ] }, "reaction_10739067": { "compartment": "compartment_70101", "id": "reaction_10739067", "reactome": "R-SPO-428664", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275", "species_29356" ], "products": [ "species_428694", "species_29372" ], "modifiers": [ [ "species_10739064", "catalyst" ] ], "additional_components": [ "Q9P6N5", "SPAC823.11" ] }, "reaction_10739084": { "compartment": "compartment_70101", "id": "reaction_10739084", "reactome": "R-SPO-428701", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10739064", "catalyst" ] ], "additional_components": [ "Q9P6N5", "SPAC823.11" ] }, "reaction_10739049": { "compartment": "compartment_70101", "id": "reaction_10739049", "reactome": "R-SPO-428259", "name": "dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_428206", "species_29368", "species_428126" ], "products": [ "species_29356", "species_428218", "species_428256" ], "modifiers": [ [ "species_10739046", "catalyst" ] ], "additional_components": [ "species_29364", "species_29362", "species_29366", "species_113526", "SPBC3B8.07c" ] }, "reaction_10739027": { "compartment": "compartment_70101", "id": "reaction_10739027", "reactome": "R-SPO-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_428139" ], "products": [ "species_76194", "species_428126" ], "modifiers": [ [ "species_10739024", "catalyst" ] ], "additional_components": [ "O59735", "SPBC3E7.15c", "P78970", "SPAC1A6.09c" ] }, "reaction_10739055": { "compartment": "compartment_70101", "id": "reaction_10739055", "reactome": "R-SPO-428273", "name": "SPHK1 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10738404", "catalyst" ] ], "additional_components": [ "SPAC4A8.07c" ] }, "reaction_10739041": { "compartment": "compartment_70101", "id": "reaction_10739041", "reactome": "R-SPO-428214", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_113592" ], "products": [ "species_29370", "species_428275" ], "modifiers": [ [ "species_10739038", "catalyst" ] ], "additional_components": [ "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04" ] }, "reaction_10739052": { "compartment": "compartment_70101", "id": "reaction_10739052", "reactome": "R-SPO-428260", "name": "dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_428126" ], "products": [ "species_29366", "species_9025544", "species_29356" ], "modifiers": [ [ "species_10739046", "catalyst" ] ], "additional_components": [ "SPBC3B8.07c" ] }, "reaction_10757901": { "compartment": "compartment_70101", "id": "reaction_10757901", "reactome": "R-SPO-9695949", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10739036", "catalyst" ], [ "species_10757899", "inhibitor" ] ], "additional_components": [ "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04", "LigandDisplayForward?ligandId=6625", "LigandDisplayForward?ligandId=10641", "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04", "LigandDisplayForward?ligandId=10219", "LigandDisplayForward?ligandId=6624" ] }, "reaction_10739081": { "compartment": "compartment_70101", "id": "reaction_10739081", "reactome": "R-SPO-428696", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10739072", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10739075": { "compartment": "compartment_984", "id": "reaction_10739075", "reactome": "R-SPO-428690", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_109276" ], "products": [ "species_109277", "species_428662" ], "modifiers": [ [ "species_10739072", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10740345": { "compartment": "compartment_70101", "id": "reaction_10740345", "reactome": "R-SPO-879459", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740341", "species_10740336" ], "products": [ "species_10740343" ], "modifiers": [], "additional_components": [ "SPAC631.01c", "SPAC12B10.07", "Q9HGP5", "SPAC631.01c", "Q10434", "SPAC12B10.07" ] }, "reaction_10741463": { "compartment": "compartment_7660", "id": "reaction_10741463", "reactome": "R-SPO-994106", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741456", "species_10741459" ], "products": [ "species_10741461" ], "modifiers": [], "additional_components": [ "SPAC664.01c", "SPAC1834.04", "P09988", "SPAC1834.04", "P40381", "SPAC664.01c" ] }, "reaction_10741481": { "compartment": "compartment_74700", "id": "reaction_10741481", "reactome": "R-SPO-1011576", "name": "EHD proteins interact with Rabenosyn-5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741477", "species_10741468" ], "products": [ "species_10741479" ], "modifiers": [], "additional_components": [ "SPAC17G6.08", "SPAC16E8.01", "O13786", "SPAC17G6.08", "O13736", "SPAC16E8.01" ] }, "reaction_10741454": { "compartment": "compartment_70101", "id": "reaction_10741454", "reactome": "R-SPO-992708", "name": "Dual-specific AKAPs bind type I and II PKA regulatory subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734228", "species_10741450" ], "products": [ "species_10741452" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "P40376", "SPBC106.10", "SPAC23G3.05c", "Q9P7S8", "SPAC23G3.05c", "P36600", "SPAC8C9.03", "P40376", "SPBC106.10" ] }, "reaction_10741445": { "compartment": "compartment_17906", "id": "reaction_10741445", "reactome": "R-SPO-992703", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741439" ], "products": [ "species_10741443" ], "modifiers": [], "additional_components": [ "SPBC1706.03", "Q9USY7", "SPBC1706.03" ] }, "reaction_10750893": { "compartment": "compartment_7660", "id": "reaction_10750893", "reactome": "R-SPO-6791222", "name": "21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750858" ], "products": [ "species_10750866" ], "modifiers": [ [ "species_10750890", "catalyst" ], [ "species_10750562", "catalyst" ], [ "species_10750878", "catalyst" ], [ "species_10750574", "catalyst" ] ], "additional_components": [ "O59675", "SPBC29A3.12", "Q9HDY4", "SPAPB1A10.06c", "O60055", "SPBC56F2.04", "Q9USN3", "SPCC16A11.02", "O94365", "SPBC428.19c", "O60179", "SPBC23E6.04c", "Q09775", "SPAC22F3.08c", "O74340", "SPBC1A4.07c", "O60161", "SPBC19F5.02c", "Q9P6P2", "SPAC823.04", "P35551", "SPBC2D10.10c", "O60188", "SPBC244.02c", "Q10107", "SPAC18G6.07c", "O74835", "SPCC1183.07", "Q9C1X1", "SPBC713.04c", "Q10101", "SPAC18G6.14c", "Q10106", "SPAC18G6.06", "P0CT56", "SPAC3H5.05c", "P78750", "SPBC29A3.06", "O74690", "SPAC607.03c", "Q9P6N8", "SPAC823.08c", "O94683", "SPBC776.17", "O94676", "SPBC776.08c", "O94653", "SPBC31E1.06", "O13835", "SPAC19D5.05c", "Q9HE11", "SPAC20H4.01", "O13823", "SPAC19A8.07c", "P0CT57", "SPBC18H10.13", "Q9P4X3", "SPAC959.03c", "O14053", "SPCC1672.07", "P87137", "SPAC57A7.06", "O94372", "SPBC1604.06c", "O43051", "SPBC3F6.04c", "O94514", "SPBC646.10c", "Q9P7S7", "SPAC23G3.06", "O74974", "SPCC1827.01c", "Q09757", "SPAC24H6.07", "O13610", "SPBC32H8.04c", "O74777", "SPBC25B2.05", "Q1MTS0", "SPBC3B8.09", "O13878", "SPAC1B3.13", "O13910", "SPAC23C11.03", "Q9P7C0", "SPAC2E1P5.05", "Q09870", "SPAC12G12.06c", "O74892", "SPCC576.08c", "Q9HGM5", "SPBC543.06c", "P87177", "SPBC3D6.12", "Q9C0Z7", "SPAPB1E7.12", "O59675", "SPBC29A3.12", "Q9HDY4", "SPAPB1A10.06c", "O60055", "SPBC56F2.04", "Q9USN3", "SPCC16A11.02", "O94365", "SPBC428.19c", "O60179", "SPBC23E6.04c", "Q09775", "SPAC22F3.08c", "O74340", "SPBC1A4.07c", "O60161", "SPBC19F5.02c", "Q9P6P2", "SPAC823.04", "P35551", "SPBC2D10.10c", "O60188", "SPBC244.02c", "Q10107", "SPAC18G6.07c", "O74835", "SPCC1183.07", "Q9C1X1", "SPBC713.04c", "Q10101", "SPAC18G6.14c", "Q10106", "SPAC18G6.06", "P0CT56", "SPAC3H5.05c", "P78750", "SPBC29A3.06", "O74690", "SPAC607.03c", "Q9P6N8", "SPAC823.08c", "O94683", "SPBC776.17", "O94676", "SPBC776.08c", "O94653", "SPBC31E1.06", "O13835", "SPAC19D5.05c", "Q9HE11", "SPAC20H4.01", "O13823", "SPAC19A8.07c", "P0CT57", "SPBC18H10.13", "Q9P4X3", "SPAC959.03c", "O14053", "SPCC1672.07", "P87137", "SPAC57A7.06", "O94372", "SPBC1604.06c", "O43051", "SPBC3F6.04c", "O94514", "SPBC646.10c", "Q9P7S7", "SPAC23G3.06", "O74974", "SPCC1827.01c", "Q09757", "SPAC24H6.07", "O13610", "SPBC32H8.04c", "O74777", "SPBC25B2.05", "Q1MTS0", "SPBC3B8.09", "O13878", "SPAC1B3.13", "O13910", "SPAC23C11.03", "Q9P7C0", "SPAC2E1P5.05", "Q09870", "SPAC12G12.06c", "O74892", "SPCC576.08c", "Q9HGM5", "SPBC543.06c", "P87177", "SPBC3D6.12", "Q9C0Z7", "SPAPB1E7.12", "O14232", "SPAC6F12.16c", "O74918", "SPCC757.08", "O60124", "SPBC16G5.10", "O42872", "SPAC3G9.10c", "O74469", "SPCC1739.07", "Q10146", "SPAC1F3.01", "Q9P7R3", "SPBC211.08c", "O59821", "SPCC1840.11", "Q09704", "SPAC2F7.14c", "O14076", "SPACUNK4.11c", "O42894", "SPBC115.01c", "Q10205", "SPBC17D1.03c", "O13903", "SPAC22A12.12c", "SPAC6F12.16c", "SPBC115.01c", "SPAC1F3.01" ] }, "reaction_10751111": { "compartment": "compartment_70101", "id": "reaction_10751111", "reactome": "R-SPO-6791223", "name": "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751081", "species_10751079" ], "products": [ "species_10751095", "species_10751085", "species_10751089", "species_10751103", "species_10751083", "species_10751087", "species_10751081", "species_10751093", "species_10751097", "species_10751091", "species_10731692" ], "modifiers": [ [ "species_10751087", "catalyst" ], [ "species_10751097", "catalyst" ], [ "species_10751109", "catalyst" ], [ "species_10751103", "catalyst" ] ], "additional_components": [ "SPAC10F6.10", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "Q10312", "SPAC6C3.09", "P40236", "SPAC23C4.12", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "P87120", "SPAC3A12.04c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9P7W5", "SPBC1703.05", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P40235", "SPBC3H7.15", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O60071", "SPBC13G1.09", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "Q9UTK0", "SPAC1486.09", "O94715", "SPCC1393.03", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "Q9Y813", "SPBC1105.16c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "Q10191", "SPAC3F10.17", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "O14044", "SPAC2C4.11c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "O13956", "SPAC23H4.15", "Q9UTQ6", "SPAC1071.07c", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "O42650", "SPAC10F6.10", "SPAC10F6.10", "SPAC3F10.17", "SPAC2C4.11c", "P40235", "SPBC3H7.15", "P40236", "SPAC23C4.12", "SPBC13G1.09", "SPAC1486.09", "SPAC10F6.10", "SPAC23H4.15", "SPBC3H7.15", "SPBC1703.05", "O59675", "SPBC29A3.12", "Q9P7B2", "SPAC521.05", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P0CT74", "SPAC144.11", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P87158", "SPBC19F8.08", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0CT76", "SPBP4H10.13", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT80", "SPCC285.15c", "P0CT64", "SPBC18H10.14", "Q9UTG4", "SPAC1805.11c", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "P0CT58", "SPAC22A12.04c", "O13614", "SPBP22H7.08", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q9UTQ6", "SPAC1071.07c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "Q9P4W9", "SPAC959.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "O74172", "SPBC3D6.15", "P0CT66", "SPBC16D10.11c", "SPAC1486.09", "SPBC3H7.15", "SPAC26A3.06", "P40235", "SPBC3H7.15", "P40236", "SPAC23C4.12" ] }, "reaction_10750611": { "compartment": "compartment_7660", "id": "reaction_10750611", "reactome": "R-SPO-6791219", "name": "32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750595" ], "products": [ "species_10750552" ], "modifiers": [ [ "species_10750593", "catalyst" ], [ "species_10750543", "catalyst" ], [ "species_10750609", "catalyst" ], [ "species_10750548", "catalyst" ] ], "additional_components": [ "Q9UU96", "SPCC830.03", "O42936", "SPBC16C6.12c", "Q9URY0", "SPAC890.04c", "O74399", "SPBC4F6.13c", "O94718", "SPCC1393.06c", "P87243", "SPCC4G3.18", "O42957", "SPBC19G7.09", "Q10272", "SPAC13G7.08c", "O60164", "SPBC19F5.05c", "Q9UU96", "SPCC830.03", "O42936", "SPBC16C6.12c", "O94718", "SPCC1393.06c", "P87243", "SPCC4G3.18", "O42957", "SPBC19G7.09", "Q10272", "SPAC13G7.08c", "Q9URY0", "SPAC890.04c", "O74399", "SPBC4F6.13c", "O60164", "SPBC19F5.05c", "SPBC16C6.12c", "O13802", "SPAC17H9.05", "O74791", "SPBC26H8.08c", "O60164", "SPBC19F5.05c", "SPCC830.03" ] }, "reaction_10732544": { "compartment": "compartment_70101", "id": "reaction_10732544", "reactome": "R-SPO-73798", "name": "AICAR + 10-Formyl-THF => FAICAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111409", "species_419151" ], "products": [ "species_111427", "species_111355" ], "modifiers": [ [ "species_10732538", "catalyst" ] ], "additional_components": [ "O74928", "SPCPB16A4.03c" ] }, "reaction_10757804": { "compartment": "compartment_70101", "id": "reaction_10757804", "reactome": "R-SPO-9678749", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732525", "species_9678719" ], "products": [ "species_10732528" ], "modifiers": [], "additional_components": [ "O14344", "SPBC2F12.14c", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "O14344", "SPBC2F12.14c", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842" ] }, "reaction_10732518": { "compartment": "compartment_70101", "id": "reaction_10732518", "reactome": "R-SPO-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111584", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29404", "species_111294", "species_76577", "species_113578" ], "modifiers": [ [ "species_10732515", "catalyst" ] ], "additional_components": [ "SPBC2F12.14c" ] }, "reaction_10732530": { "compartment": "compartment_70101", "id": "reaction_10732530", "reactome": "R-SPO-73794", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_111584" ], "modifiers": [ [ "species_10732525", "catalyst" ], [ "species_10732528", "inhibitor" ], [ "species_111584", "inhibitor" ] ], "additional_components": [ "O14344", "SPBC2F12.14c", "O14344", "SPBC2F12.14c", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842" ] }, "reaction_10734091": { "compartment": "compartment_70101", "id": "reaction_10734091", "reactome": "R-SPO-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29438", "species_29448" ], "products": [ "species_70106", "species_35141", "species_29372", "species_29420" ], "modifiers": [ [ "species_10734088", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_113578", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_30014", "inhibitor" ] ], "additional_components": [ "Q02787", "SPAC144.03", "species_29926" ] }, "reaction_10732576": { "compartment": "compartment_70101", "id": "reaction_10732576", "reactome": "R-SPO-73814", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_113592", "species_111292" ], "products": [ "species_70106", "species_29370", "species_111338", "species_29372" ], "modifiers": [ [ "species_10732559", "catalyst" ] ], "additional_components": [ "SPBC405.01" ] }, "reaction_10732570": { "compartment": "compartment_70101", "id": "reaction_10732570", "reactome": "R-SPO-73812", "name": "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111354", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29370", "species_111369", "species_29404", "species_29372" ], "modifiers": [ [ "species_10732567", "catalyst" ] ], "additional_components": [ "SPAC6F12.10c" ] }, "reaction_10732573": { "compartment": "compartment_70101", "id": "reaction_10732573", "reactome": "R-SPO-73813", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111338", "species_419151" ], "products": [ "species_70106", "species_111354", "species_111355" ], "modifiers": [ [ "species_10732559", "catalyst" ] ], "additional_components": [ "SPBC405.01" ] }, "reaction_10732541": { "compartment": "compartment_70101", "id": "reaction_10732541", "reactome": "R-SPO-73797", "name": "FAICAR => IMP + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111427" ], "products": [ "species_29602", "species_29356" ], "modifiers": [ [ "species_10732538", "catalyst" ] ], "additional_components": [ "O74928", "SPCPB16A4.03c" ] }, "reaction_10732554": { "compartment": "compartment_70101", "id": "reaction_10732554", "reactome": "R-SPO-73800", "name": "SAICAR => AICAR + Fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111399" ], "products": [ "species_29586", "species_111409" ], "modifiers": [ [ "species_10732551", "catalyst" ] ], "additional_components": [ "O60105", "SPBC14F5.09c" ] }, "reaction_10732578": { "compartment": "compartment_70101", "id": "reaction_10732578", "reactome": "R-SPO-73828", "name": "adenylosuccinate => adenosine 5'-monophosphate + fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_35141" ], "products": [ "species_29586", "species_76577" ], "modifiers": [ [ "species_10732551", "catalyst" ] ], "additional_components": [ "O60105", "SPBC14F5.09c" ] }, "reaction_10732562": { "compartment": "compartment_70101", "id": "reaction_10732562", "reactome": "R-SPO-73810", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111369" ], "products": [ "species_70106", "species_29370", "species_111370", "species_29372" ], "modifiers": [ [ "species_10732559", "catalyst" ] ], "additional_components": [ "SPBC405.01" ] }, "reaction_10739670": { "compartment": "compartment_7660", "id": "reaction_10739670", "reactome": "R-SPO-448955", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10739644", "species_10739654" ], "products": [ "species_113582", "species_10739667" ], "modifiers": [ [ "species_10739654", "catalyst" ] ], "additional_components": [ "SPBC317.01", "Q09892", "SPAC24B11.06c", "Q09892", "SPAC24B11.06c", "Q9HGP0", "SPBC317.01", "Q09892", "SPAC24B11.06c" ] }, "reaction_10754565": { "compartment": "compartment_12045", "id": "reaction_10754565", "reactome": "R-SPO-8857686", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549167", "species_10754559" ], "products": [ "species_10754563" ], "modifiers": [], "additional_components": [ "SPBC543.08", "Q9HGM4", "SPBC543.08", "species_549167" ] }, "reaction_10732605": { "compartment": "compartment_5460", "id": "reaction_10732605", "reactome": "R-SPO-73920", "name": "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73911", "species_113526" ], "products": [ "species_73909", "species_29362", "species_113529" ], "modifiers": [ [ "species_10732592", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10744280": { "compartment": "compartment_7660", "id": "reaction_10744280", "reactome": "R-SPO-3371518", "name": "SIRT1 binds to HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738936", "species_10744242" ], "products": [ "species_10744244" ], "modifiers": [], "additional_components": [ "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O94640", "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06" ] }, "reaction_10747248": { "compartment": "compartment_7660", "id": "reaction_10747248", "reactome": "R-SPO-5682026", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747243", "species_29358" ], "products": [ "species_10737781", "species_113582", "species_10747245" ], "modifiers": [ [ "species_10747243", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "SPCC23B6.03c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744330": { "compartment": "compartment_70101", "id": "reaction_10744330", "reactome": "R-SPO-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744328", "species_10744326" ], "products": [ "species_10744167" ], "modifiers": [], "additional_components": [ "O59855", "SPCC1739.13", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q09912", "SPCC830.07c", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11" ] }, "reaction_10745619": { "compartment": "compartment_7660", "id": "reaction_10745619", "reactome": "R-SPO-5333051", "name": "RPA1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729504", "species_10744252" ], "products": [ "species_10745617" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q92373", "SPCC1753.01c", "Q02953", "SPAC2E12.02", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c" ] }, "reaction_10746067": { "compartment": "compartment_70101", "id": "reaction_10746067", "reactome": "R-SPO-5618107", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10744276" ], "products": [ "species_10746061" ], "modifiers": [], "additional_components": [ "O59855", "SPCC1739.13", "P41887", "SPAC926.04c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q9USI5", "SPCC645.14c", "O59855", "SPCC1739.13", "P41887", "SPAC926.04c", "species_29370", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q9USI5", "SPCC645.14c" ] }, "reaction_10747237": { "compartment": "compartment_7660", "id": "reaction_10747237", "reactome": "R-SPO-5682020", "name": "MRN complex binds shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3785706", "species_10733251" ], "products": [ "species_10747220" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744259": { "compartment": "compartment_7660", "id": "reaction_10744259", "reactome": "R-SPO-3371467", "name": "SIRT1 deacetylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_427523", "species_10744244" ], "products": [ "species_10738936", "species_427498", "species_427497", "species_10744256" ], "modifiers": [ [ "species_10744244", "catalyst" ] ], "additional_components": [ "O94640", "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "SPBC16D10.07c", "O59855", "SPCC1739.13", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O94640", "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06" ] }, "reaction_10744307": { "compartment": "compartment_70101", "id": "reaction_10744307", "reactome": "R-SPO-3371531", "name": "Constitutive phosphorylation by pERK1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10744185" ], "products": [ "species_29370", "species_10744298" ], "modifiers": [ [ "species_10744304", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10744172": { "compartment": "compartment_70101", "id": "reaction_10744172", "reactome": "R-SPO-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744167" ], "products": [ "species_10744169", "species_29372" ], "modifiers": [ [ "species_10744167", "catalyst" ], [ "species_10744165", "catalyst" ] ], "additional_components": [ "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "Q09912", "SPCC830.07c", "O74752", "SPBC1734.11" ] }, "reaction_10744208": { "compartment": "compartment_70101", "id": "reaction_10744208", "reactome": "R-SPO-3371435", "name": "Constitutive phosphorylation by GSK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10744185" ], "products": [ "species_29370", "species_10744193" ], "modifiers": [ [ "species_10744205", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q9URT9", "SPBC8D2.01", "Q10452", "SPAC1687.15" ] }, "reaction_10747235": { "compartment": "compartment_7660", "id": "reaction_10747235", "reactome": "R-SPO-5682018", "name": "MRN complex bound to shortened telomeres recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747220", "species_10747231" ], "products": [ "species_10747233" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "O74630", "SPCC23B6.03c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744278": { "compartment": "compartment_70101", "id": "reaction_10744278", "reactome": "R-SPO-3371503", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744264", "species_10744169", "species_10744270" ], "products": [ "species_10744165", "species_10744276" ], "modifiers": [], "additional_components": [ "SPCC645.14c", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "P41887", "SPAC926.04c", "Q09912", "SPCC830.07c", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "P41887", "SPAC926.04c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q9USI5", "SPCC645.14c" ] }, "reaction_10738160": { "compartment": "compartment_12045", "id": "reaction_10738160", "reactome": "R-SPO-381091", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738152", "species_113592" ], "products": [ "species_10738157", "species_29370" ], "modifiers": [ [ "species_10738152", "catalyst" ] ], "additional_components": [ "O94537", "SPAC167.01", "O94537", "SPAC167.01", "O94537", "SPAC167.01" ] }, "reaction_10738162": { "compartment": "compartment_12045", "id": "reaction_10738162", "reactome": "R-SPO-381109", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738150" ], "products": [ "species_10738152" ], "modifiers": [], "additional_components": [ "SPAC167.01", "O94537", "SPAC167.01" ] }, "reaction_10751159": { "compartment": "compartment_7660", "id": "reaction_10751159", "reactome": "R-SPO-6792712", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747233", "species_113560" ], "products": [ "species_10747243", "species_2485002" ], "modifiers": [ [ "species_10747233", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10752180": { "compartment": "compartment_70101", "id": "reaction_10752180", "reactome": "R-SPO-6799545", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6799540", "species_29356" ], "products": [ "species_429579", "species_6799543" ], "modifiers": [ [ "species_10752177", "catalyst" ] ], "additional_components": [ "Q9UT61", "SPAC513.05", "species_442320" ] }, "reaction_10757491": { "compartment": "compartment_70101", "id": "reaction_10757491", "reactome": "R-SPO-9638127", "name": "PGM1:Mg2+ isomerises G6P to G1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537" ], "products": [ "species_29548" ], "modifiers": [ [ "species_10757486", "catalyst" ] ], "additional_components": [ "O74374", "SPBC32F12.10", "species_29926" ] }, "reaction_10729677": { "compartment": "compartment_70101", "id": "reaction_10729677", "reactome": "R-SPO-70369", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29452" ], "products": [ "species_29410" ], "modifiers": [ [ "species_10729674", "catalyst" ] ], "additional_components": [ "Q9HDU3", "SPBPB2B2.12c", "species_113526" ] }, "reaction_10729722": { "compartment": "compartment_70101", "id": "reaction_10729722", "reactome": "R-SPO-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10729644", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10757179": { "compartment": "compartment_161320", "id": "reaction_10757179", "reactome": "R-SPO-9036727", "name": "GAA hydrolyzes lysosomal glycogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757148", "species_1605715" ], "products": [ "species_1605745", "species_10757158" ], "modifiers": [ [ "species_10757176", "catalyst" ] ], "additional_components": [ "O43062", "SPBC4C3.09", "Q09680", "SPBC4C3.09", "species_113527", "O43061", "SPBC4C3.08", "O43062", "SPBC4C3.09", "Q09680", "SPBC4C3.09", "species_113527", "O43061", "SPBC4C3.08", "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10740698": { "compartment": "compartment_70101", "id": "reaction_10740698", "reactome": "R-SPO-927789", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740694", "species_10740674" ], "products": [ "species_10740696" ], "modifiers": [], "additional_components": [ "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "P79015", "SPAC3H5.10", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "species_29420", "Q09127", "SPBC18E5.04", "P08094", "SPBP8B7.06", "P0CT76", "SPBP4H10.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "O74893", "SPCC576.09", "P0CT68", "SPAC3A12.10", "Q9P3T6", "SPAC328.10c", "Q9USR7", "SPBC577.02", "Q9UTG4", "SPAC1805.11c", "Q9P383", "SPBC13A2.01c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O42699", "SPCC1682.14", "P0CT83", "SPCC16C4.13c", "Q9P4W9", "SPAC959.07", "Q9US22", "SPAC1783.08c", "O74172", "SPBC3D6.15", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "Q9P546", "SPAPJ698.02c", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07", "SPAC16C9.06c", "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "P79015", "SPAC3H5.10", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "species_29420", "Q09127", "SPBC18E5.04", "P08094", "SPBP8B7.06", "P0CT76", "SPBP4H10.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "O74893", "SPCC576.09", "P0CT68", "SPAC3A12.10", "Q9P3T6", "SPAC328.10c", "Q9USR7", "SPBC577.02", "Q9UTG4", "SPAC1805.11c", "Q09820", "SPAC16C9.06c", "Q9P383", "SPBC13A2.01c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O42699", "SPCC1682.14", "P0CT83", "SPCC16C4.13c", "Q9P4W9", "SPAC959.07", "Q9US22", "SPAC1783.08c", "O74172", "SPBC3D6.15", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "Q9P546", "SPAPJ698.02c", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07" ] }, "reaction_10737896": { "compartment": "compartment_70101", "id": "reaction_10737896", "reactome": "R-SPO-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10737893", "catalyst" ] ], "additional_components": [ "SPAC1002.07c" ] }, "reaction_10730001": { "compartment": "compartment_70101", "id": "reaction_10730001", "reactome": "R-SPO-70634", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498", "species_113567" ], "products": [ "species_113585", "species_29968" ], "modifiers": [ [ "species_10729998", "catalyst" ] ], "additional_components": [ "SPAC4G9.20c" ] }, "reaction_10729981": { "compartment": "compartment_70101", "id": "reaction_10729981", "reactome": "R-SPO-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29448", "species_113592", "species_29356" ], "products": [ "species_29404", "species_29642", "species_111294", "species_76577" ], "modifiers": [ [ "species_10729978", "catalyst" ] ], "additional_components": [ "P78753", "SPBC119.10" ] }, "reaction_10756871": { "compartment": "compartment_5460", "id": "reaction_10756871", "reactome": "R-SPO-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013199", "species_9012592" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10737898": { "compartment": "compartment_70101", "id": "reaction_10737898", "reactome": "R-SPO-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_76194", "species_353555" ], "modifiers": [ [ "species_10737893", "catalyst" ] ], "additional_components": [ "SPAC1002.07c" ] }, "reaction_10757130": { "compartment": "compartment_70101", "id": "reaction_10757130", "reactome": "R-SPO-9034539", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10756881", "catalyst" ] ], "additional_components": [ "O59791", "SPCC320.14" ] }, "reaction_10756803": { "compartment": "compartment_5460", "id": "reaction_10756803", "reactome": "R-SPO-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10741569": { "compartment": "compartment_70101", "id": "reaction_10741569", "reactome": "R-SPO-1237129", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237176", "species_29356" ], "products": [ "species_70106", "species_1237155", "species_29372" ], "modifiers": [ [ "species_10741566", "catalyst" ] ], "additional_components": [ "species_29926", "Q9P6Q2", "SPAC644.08" ] }, "reaction_10729971": { "compartment": "compartment_5460", "id": "reaction_10729971", "reactome": "R-SPO-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113552", "species_113587" ], "modifiers": [ [ "species_10729968", "catalyst" ] ], "additional_components": [ "O94320", "SPBC725.01" ] }, "reaction_10740926": { "compartment": "compartment_70101", "id": "reaction_10740926", "reactome": "R-SPO-977324", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_936706" ], "products": [ "species_200736", "species_29372" ], "modifiers": [ [ "species_10740923", "catalyst" ] ], "additional_components": [ "O74382", "SPBC3H7.07c", "species_29926" ] }, "reaction_10742240": { "compartment": "compartment_70101", "id": "reaction_10742240", "reactome": "R-SPO-1614631", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369", "species_29356" ], "products": [ "species_1614532", "species_29382", "species_936714" ], "modifiers": [ [ "species_10742218", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10742221": { "compartment": "compartment_70101", "id": "reaction_10742221", "reactome": "R-SPO-1614567", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369" ], "products": [ "species_1614532", "species_1614594" ], "modifiers": [ [ "species_10742218", "catalyst" ], [ "species_174369", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10740937": { "compartment": "compartment_70101", "id": "reaction_10740937", "reactome": "R-SPO-977333", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_977329" ], "products": [ "species_936706", "species_29406" ], "modifiers": [ [ "species_10740934", "catalyst" ] ], "additional_components": [ "Q10349", "SPAC1F12.07" ] }, "reaction_10729901": { "compartment": "compartment_70101", "id": "reaction_10729901", "reactome": "R-SPO-70524", "name": "PXLP-K314-GPT transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_29398" ], "products": [ "species_29406", "species_29432" ], "modifiers": [ [ "species_10729896", "catalyst" ] ], "additional_components": [ "Q10334", "SPBC582.08" ] }, "reaction_10741559": { "compartment": "compartment_70101", "id": "reaction_10741559", "reactome": "R-SPO-1237119", "name": "Acireductone is oxidized to MOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237155", "species_29368" ], "products": [ "species_1237122", "species_29460" ], "modifiers": [ [ "species_10741556", "catalyst" ] ], "additional_components": [ "species_113531", "O94286", "SPBC887.01" ] }, "reaction_10741654": { "compartment": "compartment_70101", "id": "reaction_10741654", "reactome": "R-SPO-1299507", "name": "Methylthio-ribulose-P = Methylthio-ribose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237107" ], "products": [ "species_1237165" ], "modifiers": [ [ "species_10741546", "catalyst" ] ], "additional_components": [ "SPBC23E6.10c" ] }, "reaction_10729947": { "compartment": "compartment_70101", "id": "reaction_10729947", "reactome": "R-SPO-70573", "name": "argininosuccinate <=> fumarate + arginine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_34575" ], "products": [ "species_29586", "species_29468" ], "modifiers": [ [ "species_10729944", "catalyst" ] ], "additional_components": [ "P50514", "SPBC1539.03c" ] }, "reaction_10757135": { "compartment": "compartment_5460", "id": "reaction_10757135", "reactome": "R-SPO-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756666", "species_9012592" ], "products": [ "species_10757133", "species_113557" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01", "SPCC4B3.01", "SPCC4B3.01" ] }, "reaction_10740139": { "compartment": "compartment_5460", "id": "reaction_10740139", "reactome": "R-SPO-507749", "name": "PXLP-K341-GPT2 transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113557" ], "products": [ "species_113594", "species_379697" ], "modifiers": [ [ "species_10740136", "catalyst" ] ], "additional_components": [ "Q10334", "SPBC582.08" ] }, "reaction_10737914": { "compartment": "compartment_70101", "id": "reaction_10737914", "reactome": "R-SPO-351222", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284" ], "products": [ "species_353113", "species_113528" ], "modifiers": [ [ "species_10737911", "catalyst" ] ], "additional_components": [ "SPBP4H10.05c" ] }, "reaction_10742237": { "compartment": "compartment_70101", "id": "reaction_10742237", "reactome": "R-SPO-1614614", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_29356" ], "products": [ "species_1614532", "species_200736" ], "modifiers": [ [ "species_10742218", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10749651": { "compartment": "compartment_876", "id": "reaction_10749651", "reactome": "R-SPO-5693783", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693762" ], "products": [ "species_29404", "species_5693772" ], "modifiers": [ [ "species_10749648", "catalyst" ] ], "additional_components": [ "O43023", "SPBC354.09c" ] }, "reaction_10755607": { "compartment": "compartment_70101", "id": "reaction_10755607", "reactome": "R-SPO-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10755604", "catalyst" ] ], "additional_components": [ "SPBC1778.07" ] }, "reaction_10730041": { "compartment": "compartment_70101", "id": "reaction_10730041", "reactome": "R-SPO-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10730038", "catalyst" ] ], "additional_components": [ "SPAC144.04c" ] }, "reaction_10729917": { "compartment": "compartment_5460", "id": "reaction_10729917", "reactome": "R-SPO-70555", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113561", "species_29896", "species_113593" ], "products": [ "species_29676", "species_113548", "species_113581" ], "modifiers": [ [ "species_10729914", "catalyst" ], [ "species_30471", "catalyst" ] ], "additional_components": [ "SPAC22G7.06c" ] }, "reaction_10756873": { "compartment": "compartment_5460", "id": "reaction_10756873", "reactome": "R-SPO-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10756884": { "compartment": "compartment_70101", "id": "reaction_10756884", "reactome": "R-SPO-9014741", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_376186" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10756881", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "O59791", "SPCC320.14" ] }, "reaction_10729937": { "compartment": "compartment_70101", "id": "reaction_10729937", "reactome": "R-SPO-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29356" ], "products": [ "species_29498", "species_29514" ], "modifiers": [ [ "species_10729934", "catalyst" ] ], "additional_components": [ "species_113527", "Q10066", "SPAC3H1.07" ] }, "reaction_10729927": { "compartment": "compartment_5460", "id": "reaction_10729927", "reactome": "R-SPO-70560", "name": "carbamoyl phosphate + ornithine => citrulline + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29676", "species_113585" ], "products": [ "species_113548", "species_113567" ], "modifiers": [ [ "species_10729924", "catalyst" ] ], "additional_components": [ "P31317", "SPAC4G9.10" ] }, "reaction_10756887": { "compartment": "compartment_70101", "id": "reaction_10756887", "reactome": "R-SPO-9014766", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_376186" ], "modifiers": [ [ "species_10756881", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "O59791", "SPCC320.14" ] }, "reaction_10755833": { "compartment": "compartment_70101", "id": "reaction_10755833", "reactome": "R-SPO-8932980", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_8932979" ], "modifiers": [ [ "species_10755830", "catalyst" ] ], "additional_components": [ "Q9HDY3", "SPAPB1A10.07c" ] }, "reaction_10756669": { "compartment": "compartment_5460", "id": "reaction_10756669", "reactome": "R-SPO-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10741579": { "compartment": "compartment_70101", "id": "reaction_10741579", "reactome": "R-SPO-1237160", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353106", "species_29372" ], "products": [ "species_83951", "species_1237165" ], "modifiers": [ [ "species_10741576", "catalyst" ] ], "additional_components": [ "Q09816", "SPAC16C9.02c" ] }, "reaction_10737906": { "compartment": "compartment_70101", "id": "reaction_10737906", "reactome": "R-SPO-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_353106", "species_204635" ], "modifiers": [ [ "species_10737903", "catalyst" ] ], "additional_components": [ "SPBC12C2.07c" ] }, "reaction_10729958": { "compartment": "compartment_70101", "id": "reaction_10729958", "reactome": "R-SPO-70581", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76213", "species_29404" ], "products": [ "species_29448", "species_29406" ], "modifiers": [ [ "species_10729955", "catalyst" ] ], "additional_components": [ "O42652", "SPAC10F6.13c" ] }, "reaction_10742227": { "compartment": "compartment_70101", "id": "reaction_10742227", "reactome": "R-SPO-1614591", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707" ], "products": [ "species_1614532", "species_1614582" ], "modifiers": [ [ "species_10742218", "catalyst" ], [ "species_111707", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10729909": { "compartment": "compartment_5460", "id": "reaction_10729909", "reactome": "R-SPO-70542", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113559" ], "products": [ "species_29374", "species_30471" ], "modifiers": [ [ "species_10729906", "catalyst" ], [ "species_374064", "catalyst" ] ], "additional_components": [ "SPAC4G9.09c" ] }, "reaction_10739964": { "compartment": "compartment_5460", "id": "reaction_10739964", "reactome": "R-SPO-452036", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_374064" ], "products": [ "species_113585", "species_374061" ], "modifiers": [ [ "species_10739961", "catalyst" ] ], "additional_components": [ "species_113527", "Q10066", "SPAC3H1.07", "P37818", "SPBP26C9.02c" ] }, "reaction_10734644": { "compartment": "compartment_7660", "id": "reaction_10734644", "reactome": "R-SPO-156682", "name": "PLK1 phosphorylates NUDC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734638" ], "products": [ "species_29370", "species_10734642" ], "modifiers": [ [ "species_10734630", "catalyst" ] ], "additional_components": [ "SPBC19F8.02", "SPBC19F8.02", "SPAC23C11.16" ] }, "reaction_10734452": { "compartment": "compartment_7660", "id": "reaction_10734452", "reactome": "R-SPO-112396", "name": "Separation of elongating transcript from template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734448" ], "products": [ "species_10734450" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734466": { "compartment": "compartment_7660", "id": "reaction_10734466", "reactome": "R-SPO-113412", "name": "Pol II elongation complex moves on the template as transcript elongates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10734436" ], "products": [ "species_9757634", "species_10734448" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734438": { "compartment": "compartment_7660", "id": "reaction_10734438", "reactome": "R-SPO-112385", "name": "Addition of nucleotides leads to transcript elongation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10734434" ], "products": [ "species_10732494", "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O42668", "SPAC27D7.14c", "O74995", "SPCC1682.07", "A0ZWU1", "SPCC1223.10c", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "P36613", "SPBP16F5.02", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734460": { "compartment": "compartment_7660", "id": "reaction_10734460", "reactome": "R-SPO-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734363", "species_10734299" ], "products": [ "species_10734365" ], "modifiers": [], "additional_components": [ "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13936", "SPAC23C4.19", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10734370": { "compartment": "compartment_7660", "id": "reaction_10734370", "reactome": "R-SPO-112383", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732494", "species_10730702", "species_10734304" ], "products": [ "species_10734363", "species_10732494" ], "modifiers": [ [ "species_10734304", "catalyst" ] ], "additional_components": [ "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "SPAC19B12.05c", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "SPAC19B12.05c" ] }, "reaction_10742959": { "compartment": "compartment_70101", "id": "reaction_10742959", "reactome": "R-SPO-2161549", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_265283" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10737651": { "compartment": "compartment_70101", "id": "reaction_10737651", "reactome": "R-SPO-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10737648", "catalyst" ] ], "additional_components": [ "SPAC9E9.13" ] }, "reaction_10742962": { "compartment": "compartment_70101", "id": "reaction_10742962", "reactome": "R-SPO-2161614", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_879629" ], "products": [ "species_29366", "species_2142710" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10748696": { "compartment": "compartment_70101", "id": "reaction_10748696", "reactome": "R-SPO-5690043", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690044", "species_29356" ], "products": [ "species_76194", "species_5690064" ], "modifiers": [ [ "species_10748693", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "species_174602", "CHEBI:59554", "P87304", "SPBC31F10.02" ] }, "reaction_10755098": { "compartment": "compartment_12045", "id": "reaction_10755098", "reactome": "R-SPO-8869206", "name": "PAFAH2 hydrolyses PAF to lyso-PAF and acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8869214", "species_29356" ], "products": [ "species_8869207", "species_29416" ], "modifiers": [ [ "species_10755095", "catalyst" ] ], "additional_components": [ "SPBC106.11c" ] }, "reaction_10746338": { "compartment": "compartment_70101", "id": "reaction_10746338", "reactome": "R-SPO-5631885", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29408", "species_10744090" ], "products": [ "species_29356", "species_10746335" ], "modifiers": [ [ "species_10744090", "catalyst" ] ], "additional_components": [ "O74887", "SPCC576.03c", "O74887", "SPCC576.03c", "O74887", "SPCC576.03c" ] }, "reaction_10735170": { "compartment": "compartment_70101", "id": "reaction_10735170", "reactome": "R-SPO-165179", "name": "Formation of TSC1:TSC2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735151", "species_10735164" ], "products": [ "species_10735168" ], "modifiers": [], "additional_components": [ "SPAC630.13c", "SPAC22F3.13", "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c" ] }, "reaction_10757294": { "compartment": "compartment_7660", "id": "reaction_10757294", "reactome": "R-SPO-9613494", "name": "Unwinding of DNA for the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10733310" ], "products": [ "species_164121", "species_113541", "species_10733310" ], "modifiers": [ [ "species_10732494", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07" ] }, "reaction_10733352": { "compartment": "compartment_7660", "id": "reaction_10733352", "reactome": "R-SPO-75869", "name": "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733310" ], "products": [ "species_10733350", "species_10732624", "species_113541" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "SPAC16E8.16", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10734065": { "compartment": "compartment_7660", "id": "reaction_10734065", "reactome": "R-SPO-111264", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733549" ], "products": [ "species_113541", "species_10733586" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10753227": { "compartment": "compartment_7660", "id": "reaction_10753227", "reactome": "R-SPO-6810233", "name": "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10753215" ], "products": [ "species_113582", "species_10753224" ], "modifiers": [ [ "species_10753215", "catalyst" ] ], "additional_components": [ "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "O14098", "SPAC2F3.15", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "O59748", "SPBC530.13", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "O14098", "SPAC2F3.15", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O59748", "SPBC530.13", "O60076", "SPCC1494.02c", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "O14098", "SPAC2F3.15", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "O59748", "SPBC530.13" ] }, "reaction_10733584": { "compartment": "compartment_7660", "id": "reaction_10733584", "reactome": "R-SPO-77069", "name": "RNA Polymerase II CTD (phosphorylated) binds to CE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733582", "species_10733576" ], "products": [ "species_10733578" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "SPBC2F12.08c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733356": { "compartment": "compartment_7660", "id": "reaction_10733356", "reactome": "R-SPO-75873", "name": "Addition of Nucleotides 5 through 9 on the growing Transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733350" ], "products": [ "species_10733354", "species_10732699", "species_10732619", "species_10732711", "species_113541" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10757296": { "compartment": "compartment_7660", "id": "reaction_10757296", "reactome": "R-SPO-9613497", "name": "Unwinding DNA for the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10732713" ], "products": [ "species_10732713", "species_113541" ], "modifiers": [ [ "species_10732494", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07" ] }, "reaction_10734472": { "compartment": "compartment_7660", "id": "reaction_10734472", "reactome": "R-SPO-113430", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733586" ], "products": [ "species_10733586" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733580": { "compartment": "compartment_7660", "id": "reaction_10733580", "reactome": "R-SPO-77068", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733578" ], "products": [ "species_10733578" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733604": { "compartment": "compartment_7660", "id": "reaction_10733604", "reactome": "R-SPO-77073", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733578", "species_10733594", "species_10733600" ], "products": [ "species_10733602" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "SPCC330.10", "SPAC23C4.19", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733415": { "compartment": "compartment_7660", "id": "reaction_10733415", "reactome": "R-SPO-75949", "name": "RNA Polymerase II Promoter Opening: First Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10733340" ], "products": [ "species_113582", "species_113550", "species_10733332" ], "modifiers": [ [ "species_10732494", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07" ] }, "reaction_10733589": { "compartment": "compartment_7660", "id": "reaction_10733589", "reactome": "R-SPO-77071", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10733586" ], "products": [ "species_113582", "species_10733582" ], "modifiers": [ [ "species_10733586", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733551": { "compartment": "compartment_7660", "id": "reaction_10733551", "reactome": "R-SPO-76576", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733354", "species_9757634" ], "products": [ "species_113541", "species_10733549" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10752508": { "compartment": "compartment_7660", "id": "reaction_10752508", "reactome": "R-SPO-6802973", "name": "PLK3 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732945", "species_29358" ], "products": [ "species_113582", "species_10752503" ], "modifiers": [ [ "species_10752505", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC23C11.16" ] }, "reaction_10733313": { "compartment": "compartment_7660", "id": "reaction_10733313", "reactome": "R-SPO-75850", "name": "Addition of the third nucleotide on the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10732713" ], "products": [ "species_113541", "species_10733310" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10757952": { "compartment": "compartment_70101", "id": "reaction_10757952", "reactome": "R-SPO-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_29366", "species_469662" ], "modifiers": [ [ "species_10744798", "catalyst" ] ], "additional_components": [ "SPAC7D4.09c" ] }, "reaction_10736294": { "compartment": "compartment_17957", "id": "reaction_10736294", "reactome": "R-SPO-194023", "name": "HSD11B2,HSD11B1 dimer oxidise CORT to COR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_193977" ], "products": [ "species_70106", "species_29364", "species_194035" ], "modifiers": [ [ "species_10736291", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10740318": { "compartment": "compartment_70101", "id": "reaction_10740318", "reactome": "R-SPO-804969", "name": "HSD17B1 hydrogenates E1 to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193066" ], "products": [ "species_29366", "species_193132" ], "modifiers": [ [ "species_10740315", "catalyst" ] ], "additional_components": [ "O74628", "SPCC162.03" ] }, "reaction_10736285": { "compartment": "compartment_70101", "id": "reaction_10736285", "reactome": "R-SPO-193961", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196366" ], "products": [ "species_193092" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10750043": { "compartment": "compartment_5460", "id": "reaction_10750043", "reactome": "R-SPO-5696822", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696835", "species_113563" ], "products": [ "species_113600", "species_5696848", "species_113529" ], "modifiers": [ [ "species_10750040", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736362": { "compartment": "compartment_70101", "id": "reaction_10736362", "reactome": "R-SPO-196372", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193124", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196366" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10754586": { "compartment": "compartment_70101", "id": "reaction_10754586", "reactome": "R-SPO-8862137", "name": "HSD17B2 oxidises estradiol (E2) to estrone (E1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_176619" ], "products": [ "species_70106", "species_29364", "species_193066" ], "modifiers": [ [ "species_10754583", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10736243": { "compartment": "compartment_70101", "id": "reaction_10736243", "reactome": "R-SPO-193073", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_176626" ], "products": [ "species_70106", "species_73473", "species_193079" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10743335": { "compartment": "compartment_70101", "id": "reaction_10743335", "reactome": "R-SPO-2509831", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509848", "species_29356" ], "products": [ "species_70106", "species_111584", "species_111294" ], "modifiers": [ [ "species_10743329", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q9UU89", "SPCC830.10" ] }, "reaction_10743338": { "compartment": "compartment_70101", "id": "reaction_10743338", "reactome": "R-SPO-2509838", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509835", "species_29356" ], "products": [ "species_70106", "species_9731659", "species_111294" ], "modifiers": [ [ "species_10743329", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q9UU89", "SPCC830.10" ] }, "reaction_10732747": { "compartment": "compartment_70101", "id": "reaction_10732747", "reactome": "R-SPO-74255", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29356", "species_83956" ], "products": [ "species_30064", "species_31633" ], "modifiers": [ [ "species_10732744", "catalyst" ] ], "additional_components": [ "species_442320", "O14057", "SPCC1672.03c" ] }, "reaction_10743097": { "compartment": "compartment_70101", "id": "reaction_10743097", "reactome": "R-SPO-2393939", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1131972" ], "products": [ "species_73578", "species_76577" ], "modifiers": [ [ "species_10743094", "catalyst" ] ], "additional_components": [ "Q9P791", "SPBP35G2.12", "species_29926" ] }, "reaction_10743332": { "compartment": "compartment_70101", "id": "reaction_10743332", "reactome": "R-SPO-2509827", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2509836" ], "products": [ "species_70106", "species_29602", "species_111294" ], "modifiers": [ [ "species_10743329", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q9UU89", "SPCC830.10" ] }, "reaction_10756339": { "compartment": "compartment_70101", "id": "reaction_10756339", "reactome": "R-SPO-8953339", "name": "DNPH1 hydrolyses dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_109327" ], "products": [ "species_8953344", "species_83956" ], "modifiers": [ [ "species_10756336", "catalyst" ] ], "additional_components": [ "SPCC191.05c" ] }, "reaction_10733620": { "compartment": "compartment_7660", "id": "reaction_10733620", "reactome": "R-SPO-77081", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113571", "species_10733610" ], "products": [ "species_10733617", "species_111349" ], "modifiers": [ [ "species_10733610", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "species_29626", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733608": { "compartment": "compartment_7660", "id": "reaction_10733608", "reactome": "R-SPO-77077", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733602", "species_72084", "species_29428" ], "products": [ "species_10733606" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733634": { "compartment": "compartment_7660", "id": "reaction_10733634", "reactome": "R-SPO-77090", "name": "Methylation of GMP-cap by RNA Methyltransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733627", "species_77087" ], "products": [ "species_10732494", "species_10733631", "species_10730700", "species_10733600", "species_77502" ], "modifiers": [ [ "species_10733627", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "P40997", "SPBC2F12.08c", "O74880", "SPCC330.10", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "SPAC23C4.19", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733629": { "compartment": "compartment_7660", "id": "reaction_10733629", "reactome": "R-SPO-77085", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733622" ], "products": [ "species_10733627" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733636": { "compartment": "compartment_7660", "id": "reaction_10733636", "reactome": "R-SPO-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10730619", "species_10730614" ], "products": [ "species_10730621" ], "modifiers": [], "additional_components": [ "SPAC6G10.07", "SPBC13A2.01c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07" ] }, "reaction_10733625": { "compartment": "compartment_7660", "id": "reaction_10733625", "reactome": "R-SPO-77083", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733617" ], "products": [ "species_10733622" ], "modifiers": [ [ "species_10733617", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "species_29626", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "species_29626", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733613": { "compartment": "compartment_7660", "id": "reaction_10733613", "reactome": "R-SPO-77078", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733606" ], "products": [ "species_113550", "species_10733610" ], "modifiers": [ [ "species_10733606", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733638": { "compartment": "compartment_7660", "id": "reaction_10733638", "reactome": "R-SPO-77095", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10730621", "species_10730700" ], "products": [ "species_10730702" ], "modifiers": [], "additional_components": [ "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10742810": { "compartment": "compartment_70616", "id": "reaction_10742810", "reactome": "R-SPO-1955380", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742804", "species_10742802", "species_10742777" ], "products": [ "species_10742808" ], "modifiers": [], "additional_components": [ "SPCC24B10.05", "Q9P7K0", "SPCC24B10.05", "Q9USM7", "SPCC16A11.09c", "Q09188", "SPBC530.10c", "Q9UTE9", "SPAC222.03c", "P87130", "SPAC3A12.16c", "P87146", "SPBC25H2.04c", "SPBC25H2.04c", "Q9P7K0", "SPCC24B10.05", "Q9USM7", "SPCC16A11.09c", "Q09188", "SPBC530.10c", "Q9UTE9", "SPAC222.03c", "P87130", "SPAC3A12.16c", "P87146", "SPBC25H2.04c" ] }, "reaction_10756553": { "compartment": "compartment_5460", "id": "reaction_10756553", "reactome": "R-SPO-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756545" ], "products": [], "modifiers": [ [ "species_10756550", "catalyst" ] ], "additional_components": [ "O74831", "SPCC1183.03c", "P31317", "SPAC4G9.10", "Q9UTL6", "SPAC144.08", "Q09864", "SPAC12G12.04", "SPBC119.17" ] }, "reaction_10757288": { "compartment": "compartment_70101", "id": "reaction_10757288", "reactome": "R-SPO-9609921", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757284", "species_10757262" ], "products": [ "species_10757286" ], "modifiers": [], "additional_components": [ "O13644", "SPBC8D2.14c", "Q92356", "SPAC6G9.11", "O42646", "SPAC10F6.05c", "O43002", "SPBC2G2.03c", "O60119", "SPBC16G5.05c", "Q9USM6", "SPCC16A11.10c", "Q9USH7", "SPCC825.03c", "Q09827", "SPAC4G8.02c", "O13797", "SPAC1142.02c", "O13644", "SPBC8D2.14c", "Q92356", "SPAC6G9.11", "O42646", "SPAC10F6.05c", "O13797", "SPAC1142.02c", "O43002", "SPBC2G2.03c", "O60119", "SPBC16G5.05c", "Q9USM6", "SPCC16A11.10c", "Q9USH7", "SPCC825.03c", "Q09827", "SPAC4G8.02c" ] }, "reaction_10757305": { "compartment": "compartment_70101", "id": "reaction_10757305", "reactome": "R-SPO-9617595", "name": "SGTA binds mislocalized membrane protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757262", "species_10757280" ], "products": [ "species_10757303" ], "modifiers": [], "additional_components": [ "O13797", "SPAC1142.02c", "SPAC6G9.11", "Q92356", "SPAC6G9.11", "O13797", "SPAC1142.02c" ] } }, "collapsed_reaction_dictionary": { "reaction_10736615": { "compartment": "compartment_70101", "id": "reaction_10736615", "reactome": "R-SPO-198640", "name": "TORC2 (mTOR) phosphorylates AKT at S473", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10736578" ], "products": [ "species_29370", "species_10736485" ], "modifiers": [ [ "species_10736612", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "O14208", "SPAC6B12.03c", "Q09743", "SPBC12C2.02c", "Q9Y7K2", "SPBC216.07c", "O74547", "SPCC777.08c", "O74184", "SPBC21B10.05c", "Q9P7Y9", "SPAPYUG7.02c" ] }, "reaction_10736508": { "compartment": "compartment_70101", "id": "reaction_10736508", "reactome": "R-SPO-198270", "name": "PDPK1 phosphorylates AKT at T308", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10736487" ], "products": [ "species_10736505", "species_29370", "species_10733718" ], "modifiers": [ [ "species_10736487", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q12701", "SPCC576.15c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "species_179838", "Q12701", "SPCC576.15c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q12701", "SPCC576.15c" ] }, "reaction_10743083": { "compartment": "compartment_70101", "id": "reaction_10743083", "reactome": "R-SPO-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737088", "species_179838" ], "products": [ "species_10733718" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10738460": { "compartment": "compartment_70101", "id": "reaction_10738460", "reactome": "R-SPO-392530", "name": "p-S400-Cot phosphorylates NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10738454" ], "products": [ "species_29370", "species_10738457" ], "modifiers": [ [ "species_10738323", "catalyst" ] ], "additional_components": [ "SPAC1006.09", "SPAC1006.09", "O74304", "SPAC1006.09", "O14299", "SPAC9G1.02" ] }, "reaction_10743087": { "compartment": "compartment_70101", "id": "reaction_10743087", "reactome": "R-SPO-2317332", "name": "PIP3 recruits AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10738396" ], "products": [ "species_10736578" ], "modifiers": [], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c" ] }, "reaction_10738325": { "compartment": "compartment_70101", "id": "reaction_10738325", "reactome": "R-SPO-389756", "name": "AKT interacts and phosphorylates Cot", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10738315" ], "products": [ "species_29370", "species_10738323" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "O74304", "SPAC1006.09", "O14299", "SPAC9G1.02", "O74304", "SPAC1006.09", "O14299", "SPAC9G1.02", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10743085": { "compartment": "compartment_876", "id": "reaction_10743085", "reactome": "R-SPO-2317314", "name": "AKT binds PDPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733718", "species_10736485" ], "products": [ "species_10736487" ], "modifiers": [], "additional_components": [ "species_179838", "Q12701", "SPCC576.15c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q12701", "SPCC576.15c" ] }, "reaction_10730559": { "compartment": "compartment_70101", "id": "reaction_10730559", "reactome": "R-SPO-71732", "name": "PPA1 hydrolyzes pyrophosphate to orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10730556", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P87118", "SPAC3A12.02", "P19117", "SPAC23C11.05" ] }, "reaction_10739587": { "compartment": "compartment_12045", "id": "reaction_10739587", "reactome": "R-SPO-446214", "name": "Synthesis of dolichyl-phosphate-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_449299" ], "products": [ "species_110096", "species_532214" ], "modifiers": [ [ "species_10739584", "catalyst" ] ], "additional_components": [ "SPBC56F2.10c" ] }, "reaction_10750117": { "compartment": "compartment_7660", "id": "reaction_10750117", "reactome": "R-SPO-6781818", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5688114", "species_10732494", "species_10730706" ], "products": [ "species_10750115" ], "modifiers": [], "additional_components": [ "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q02061", "SPAC23G3.01", "P36594", "SPBC28F2.12", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O13877", "SPAC1B3.12c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O14459", "SPACUNK4.06c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10750180": { "compartment": "compartment_7660", "id": "reaction_10750180", "reactome": "R-SPO-6781833", "name": "ERCC8 (CSA) binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750176", "species_10750129" ], "products": [ "species_10750167", "species_10750178" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9UT51", "SPAC222.16c", "O14122", "SPAC3A11.08", "O94308", "SPBC215.03c", "Q9UUJ7", "SPAC1952.12c", "O13895", "SPAC22A12.03c", "O94454", "SPAC1687.13c", "Q9USR0", "SPBC577.09", "Q9HFR0", "SPAPB17E12.04c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "Q9UT51", "SPAC222.16c", "O94308", "SPBC215.03c", "Q9UUJ7", "SPAC1952.12c", "O13895", "SPAC22A12.03c", "O94454", "SPAC1687.13c", "Q9HFR0", "SPAPB17E12.04c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10750201": { "compartment": "compartment_7660", "id": "reaction_10750201", "reactome": "R-SPO-6781867", "name": "ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729044", "species_10750178" ], "products": [ "species_10750198" ], "modifiers": [ [ "species_10750178", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10750122": { "compartment": "compartment_7660", "id": "reaction_10750122", "reactome": "R-SPO-6781824", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6781829", "species_10750115" ], "products": [ "species_10750119", "species_113541" ], "modifiers": [ [ "species_10750115", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10750235": { "compartment": "compartment_7660", "id": "reaction_10750235", "reactome": "R-SPO-6782069", "name": "UVSSA:USP7 deubiquitinates ERCC6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10750226" ], "products": [ "species_10729044", "species_10750232" ], "modifiers": [ [ "species_10750226", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750182": { "compartment": "compartment_7660", "id": "reaction_10750182", "reactome": "R-SPO-6781840", "name": "ERCC6 binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750119", "species_10750127" ], "products": [ "species_10750129" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "SPCP25A2.02c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10739167": { "compartment": "compartment_70101", "id": "reaction_10739167", "reactome": "R-SPO-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739153", "species_429974" ], "products": [ "species_10739155" ], "modifiers": [], "additional_components": [ "O74499", "SPCC285.12", "O94408", "SPCC1620.01c", "Q9Y7M4", "SPBC9B6.05c", "O42978", "SPBC20F10.09", "Q9UUI1", "SPAC2F3.17c", "O42958", "SPBC19G7.10c", "P87173", "SPBC3D6.08c", "O14352", "SPBC30D10.06", "O74499", "SPCC285.12", "O94408", "SPCC1620.01c", "Q9Y7M4", "SPBC9B6.05c", "O42978", "SPBC20F10.09", "Q9UUI1", "SPAC2F3.17c", "O42958", "SPBC19G7.10c", "P87173", "SPBC3D6.08c", "O14352", "SPBC30D10.06" ] }, "reaction_10739245": { "compartment": "compartment_70101", "id": "reaction_10739245", "reactome": "R-SPO-430028", "name": "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429974", "species_29356" ], "products": [ "species_109395", "species_109402", "species_429926", "species_76577", "species_113578" ], "modifiers": [ [ "species_10739242", "catalyst" ] ], "additional_components": [ "O42872", "SPAC3G9.10c", "O59821", "SPCC1840.11", "O94474", "SPCC1919.05", "O74774", "SPBC25B2.01", "O13903", "SPAC22A12.12c", "Q09150", "SPBC32F12.02", "O74918", "SPCC757.08", "O60124", "SPBC16G5.10", "Q9P7R3", "SPBC211.08c", "O59801", "SPCC550.03c", "Q09704", "SPAC2F7.14c", "O42894", "SPBC115.01c", "Q10205", "SPBC17D1.03c", "P37202", "SPBC26H8.10" ] }, "reaction_10739165": { "compartment": "compartment_70101", "id": "reaction_10739165", "reactome": "R-SPO-429961", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429926", "species_29356" ], "products": [ "species_429925", "species_430042" ], "modifiers": [ [ "species_10739162", "catalyst" ] ], "additional_components": [ "SPBP4H10.20" ] }, "reaction_10733646": { "compartment": "compartment_7660", "id": "reaction_10733646", "reactome": "R-SPO-77589", "name": "Recognition of AAUAAA sequence by CPSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733642", "species_10731317" ], "products": [ "species_10733644" ], "modifiers": [], "additional_components": [ "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c" ] }, "reaction_10757633": { "compartment": "compartment_17938", "id": "reaction_10757633", "reactome": "R-SPO-9646468", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757563", "species_10735183" ], "products": [ "species_10757565" ], "modifiers": [], "additional_components": [ "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "species_29438", "O94363", "SPBC428.16c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757544": { "compartment": "compartment_17938", "id": "reaction_10757544", "reactome": "R-SPO-9639286", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757537", "species_29420" ], "products": [ "species_29438", "species_10757541" ], "modifiers": [ [ "species_10757537", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757608": { "compartment": "compartment_17938", "id": "reaction_10757608", "reactome": "R-SPO-9645608", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757552", "species_10757561" ], "products": [ "species_10757563" ], "modifiers": [], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "Q9Y7K2", "SPBC216.07c", "P87141", "SPAC57A7.11", "O74184", "SPBC21B10.05c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757570": { "compartment": "compartment_17938", "id": "reaction_10757570", "reactome": "R-SPO-9640195", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757565" ], "products": [ "species_10757567", "species_29372" ], "modifiers": [ [ "species_10757565", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757557": { "compartment": "compartment_17938", "id": "reaction_10757557", "reactome": "R-SPO-9640167", "name": "RRAGA,B exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757550" ], "products": [ "species_10757554", "species_29420" ], "modifiers": [ [ "species_10757550", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "species_29468", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "species_29468", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "species_29468", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757606": { "compartment": "compartment_17938", "id": "reaction_10757606", "reactome": "R-SPO-9645598", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757537" ], "products": [ "species_29372", "species_10757541" ], "modifiers": [ [ "species_10757537", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10733230": { "compartment": "compartment_70101", "id": "reaction_10733230", "reactome": "R-SPO-75125", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500006", "species_29370" ], "products": [ "species_113592", "species_500009" ], "modifiers": [ [ "species_10732253", "catalyst" ] ], "additional_components": [ "species_110096", "species_110094", "CHEBI:58593", "species_109395", "species_109378", "species_418075", "SPCC1795.05c" ] }, "reaction_10740122": { "compartment": "compartment_5460", "id": "reaction_10740122", "reactome": "R-SPO-482804", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_482803", "species_113593" ], "products": [ "species_482807", "species_113581" ], "modifiers": [ [ "species_10740119", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "P49740", "SPAC806.07" ] }, "reaction_10732360": { "compartment": "compartment_70101", "id": "reaction_10732360", "reactome": "R-SPO-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10732357", "catalyst" ] ], "additional_components": [ "O42644", "SPAC10F6.03c" ] }, "reaction_10750485": { "compartment": "compartment_7660", "id": "reaction_10750485", "reactome": "R-SPO-6788810", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788813", "species_29358" ], "products": [ "species_113582", "species_6788807" ], "modifiers": [ [ "species_10750482", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "SPCC830.11c" ] }, "reaction_10734110": { "compartment": "compartment_70101", "id": "reaction_10734110", "reactome": "R-SPO-111751", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10732350" ], "products": [ "species_10732348", "species_8866399", "species_29356" ], "modifiers": [ [ "species_10734107", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "P36603", "SPBC25D12.04", "P36602", "SPAC1F7.05", "CHEBI:29034" ] }, "reaction_10734119": { "compartment": "compartment_70101", "id": "reaction_10734119", "reactome": "R-SPO-111804", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10732350" ], "products": [ "species_10732348", "species_8866399", "species_29356" ], "modifiers": [ [ "species_10734116", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "P36602", "SPAC1F7.05", "P36603", "SPBC25D12.04", "CHEBI:29034" ] }, "reaction_10740066": { "compartment": "compartment_70101", "id": "reaction_10740066", "reactome": "R-SPO-482621", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_482625" ], "products": [ "species_482627", "species_113592" ], "modifiers": [ [ "species_10740061", "catalyst" ] ], "additional_components": [ "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "P49740", "SPAC806.07" ] }, "reaction_10733852": { "compartment": "compartment_70101", "id": "reaction_10733852", "reactome": "R-SPO-110145", "name": "AMP + ATP <=> ADP + ADP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76577" ], "products": [ "species_29370" ], "modifiers": [ [ "species_10733847", "catalyst" ] ], "additional_components": [ "SPAC4G9.03" ] }, "reaction_10732370": { "compartment": "compartment_7660", "id": "reaction_10732370", "reactome": "R-SPO-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742", "species_9668967" ], "modifiers": [ [ "species_10732367", "catalyst" ] ], "additional_components": [ "Q9P6Q5", "SPAC644.05c" ] }, "reaction_10732510": { "compartment": "compartment_70101", "id": "reaction_10732510", "reactome": "R-SPO-73788", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500071", "species_113592" ], "products": [ "species_500077", "species_29370" ], "modifiers": [ [ "species_10732507", "catalyst" ] ], "additional_components": [ "species_109327", "species_29626", "species_29420", "CHEBI:58595", "SPBC1198.05" ] }, "reaction_10752646": { "compartment": "compartment_70101", "id": "reaction_10752646", "reactome": "R-SPO-6806877", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8866401" ], "products": [ "species_29370", "species_6806881" ], "modifiers": [ [ "species_10752643", "catalyst" ] ], "additional_components": [ "P49740", "SPAC806.07" ] }, "reaction_10732322": { "compartment": "compartment_70101", "id": "reaction_10732322", "reactome": "R-SPO-73596", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_109378", "species_29356" ], "products": [ "species_109382", "species_31633" ], "modifiers": [ [ "species_10732319", "catalyst" ] ], "additional_components": [ "O43012", "SPBC2G2.13c" ] }, "reaction_10732332": { "compartment": "compartment_70101", "id": "reaction_10732332", "reactome": "R-SPO-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109382", "species_111355" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10732329", "catalyst" ] ], "additional_components": [ "Q9UTI7", "SPAC15E1.04", "species_29926" ] }, "reaction_10740131": { "compartment": "compartment_70101", "id": "reaction_10740131", "reactome": "R-SPO-504054", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10740128", "catalyst" ] ], "additional_components": [ "O42644", "SPAC10F6.03c" ] }, "reaction_10733843": { "compartment": "compartment_70101", "id": "reaction_10733843", "reactome": "R-SPO-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_113592", "species_6788778" ], "modifiers": [ [ "species_10733838", "catalyst" ] ], "additional_components": [ "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "species_109395", "species_76577", "species_109378", "species_109386", "SPAC4G9.03" ] }, "reaction_10733845": { "compartment": "compartment_70101", "id": "reaction_10733845", "reactome": "R-SPO-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6788778" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10733838", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "SPAC4G9.03" ] }, "reaction_10730480": { "compartment": "compartment_70101", "id": "reaction_10730480", "reactome": "R-SPO-71682", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_111745" ], "products": [ "species_29366", "species_29450" ], "modifiers": [ [ "species_10730477", "catalyst" ] ], "additional_components": [ "P78965", "SPBC17A3.07", "species_113596" ] }, "reaction_10739090": { "compartment": "compartment_70101", "id": "reaction_10739090", "reactome": "R-SPO-428941", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739086", "species_113592" ], "products": [ "species_29370", "species_10739088" ], "modifiers": [ [ "species_10734141", "catalyst" ] ], "additional_components": [ "SPAC24B11.06c", "SPAC24B11.06c", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10739107": { "compartment": "compartment_70101", "id": "reaction_10739107", "reactome": "R-SPO-428961", "name": "Phosphorylation of cPLA2 by MAPK p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10739104" ], "products": [ "species_29370", "species_10734190" ], "modifiers": [ [ "species_10739088", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "SPAC24B11.06c" ] }, "reaction_10732235": { "compartment": "compartment_70101", "id": "reaction_10732235", "reactome": "R-SPO-72672", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732216", "species_10731817", "species_10732225" ], "products": [ "species_10732227" ], "modifiers": [], "additional_components": [ "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "P0C016", "SPAC6G10.11c", "O42706", "SPAC959.08", "P0C8R3", "SPAC589.10c", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O14388", "SPBC685.07c", "Q09668", "SPAC11E3.15", "P52822", "SPAC3H5.12c", "P36584", "SPAPB8E5.06c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P05733", "SPCC1223.05c", "Q9P784", "SPBC1711.06", "O74864", "SPCC18.14c", "O60143", "SPBC18H10.12c", "P0CT77", "SPAC26A3.07c", "P0CT61", 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computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_10731778", "species_10734741" ], "products": [ "species_10731755", "species_10731810" ], "modifiers": [], "additional_components": [ "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "O74743", "SPBC1709.18", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10734671": { "compartment": "compartment_70101", "id": "reaction_10734671", "reactome": "R-SPO-156808", "name": "Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_10734667", "species_10734655", "species_10731778" ], "products": [ "species_10731755", "species_10734669" ], "modifiers": [], "additional_components": [ "SPBC25H2.07", "Q9P6M8", "SPAC1610.03c", "P31209", "SPAC57A7.04c", "O74743", "SPBC1709.18", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "SPBC25H2.07", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10732241": { "compartment": "compartment_70101", "id": "reaction_10732241", "reactome": "R-SPO-72676", "name": "eIF3 and eIF1A bind to the 40S subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_10731750", "species_10731692" ], "products": [ "species_10732239" ], "modifiers": [], "additional_components": [ "SPBC25H2.07", "Q09722", "SPAC1751.03", "O94513", "SPBC646.09c", "Q10425", "SPAC25G10.08", "P79083", "SPAC4D7.05", "P87128", "SPAC3A12.13c", "O43060", "SPBC4C3.07", "Q9UT48", "SPAC821.05", "P78795", "SPBC18H10.03", "O94236", "SPAC637.07", "O74760", "SPBC17D11.05", "O14164", "SPAC4A8.16c", "O59675", "SPBC29A3.12", "Q9P7B2", "SPAC521.05", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P0CT74", "SPAC144.11", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P87158", "SPBC19F8.08", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0CT76", "SPBP4H10.13", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT80", "SPCC285.15c", "P0CT64", "SPBC18H10.14", "Q9UTG4", "SPAC1805.11c", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "P0CT58", "SPAC22A12.04c", "O13614", "SPBP22H7.08", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q9UTQ6", "SPAC1071.07c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "Q9P4W9", "SPAC959.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "O74172", "SPBC3D6.15", "P0CT66", "SPBC16D10.11c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10731821": { "compartment": "compartment_70101", "id": "reaction_10731821", "reactome": "R-SPO-72621", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10731810" ], "products": [ "species_29370", "species_10731810", "species_29372" ], "modifiers": [ [ "species_72617", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10732237": { "compartment": "compartment_70101", "id": "reaction_10732237", "reactome": "R-SPO-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731774", "species_72393" ], "products": [ "species_10731776" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c" ] }, "reaction_10731823": { "compartment": "compartment_70101", "id": "reaction_10731823", "reactome": "R-SPO-72631", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731789", "species_10731794", "species_10731799" ], "products": [ "species_10731801" ], "modifiers": [], "additional_components": [ "P47943", "SPAC1006.07", "SPBC1709.18", "SPAC17C9.03", "O74743", "SPBC1709.18", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07" ] }, "reaction_10731829": { "compartment": "compartment_70101", "id": "reaction_10731829", "reactome": "R-SPO-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10731772" ], "products": [ "species_10731774" ], "modifiers": [], "additional_components": [ "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c" ] }, "reaction_10732248": { "compartment": "compartment_70101", "id": "reaction_10732248", "reactome": "R-SPO-72722", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10731860" ], "products": [ "species_10731858", "species_10731774", "species_29420" ], "modifiers": [ [ "species_10731858", "catalyst" ] ], "additional_components": [ "species_29420", "P56286", "SPAC3G9.09c", "P56288", "SPAC4D7.09", "Q09130", "SPBC17G9.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "P56329", "SPAC32A11.04c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06", "P56288", "SPAC4D7.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c", "P56288", "SPAC4D7.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06" ] }, "reaction_10731862": { "compartment": "compartment_70101", "id": "reaction_10731862", "reactome": "R-SPO-72670", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731819", "species_10731858" ], "products": [ "species_10731860" ], "modifiers": [], "additional_components": [ "species_29420", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c", "P56288", "SPAC4D7.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06", "species_29420", "P56286", "SPAC3G9.09c", "P56288", "SPAC4D7.09", "Q09130", "SPBC17G9.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "P56329", "SPAC32A11.04c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06" ] }, "reaction_10732245": { "compartment": "compartment_70101", "id": "reaction_10732245", "reactome": "R-SPO-72697", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_72617", "species_10731810", "species_10731815", "species_10731772" ], "products": [ "species_10731755", "species_72617", "species_10731810", "species_10731815", "species_10731772" ], "modifiers": [ [ "species_72617", "catalyst" ] ], "additional_components": [ "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "SPAC2F7.05c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c", "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "SPAC2F7.05c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c" ] }, "reaction_10732243": { "compartment": "compartment_70101", "id": "reaction_10732243", "reactome": "R-SPO-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732239", "species_10731776" ], "products": [ "species_10731778" ], "modifiers": [], "additional_components": [ "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10738284": { "compartment": "compartment_70101", "id": "reaction_10738284", "reactome": "R-SPO-389540", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_389545" ], "products": [ "species_70106", "species_29364", "species_113528", "species_29406" ], "modifiers": [ [ "species_10738281", "catalyst" ] ], "additional_components": [ "O14254", "SPAC6G10.08" ] }, "reaction_10734757": { "compartment": "compartment_13231", "id": "reaction_10734757", "reactome": "R-SPO-158481", "name": "Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734069" ], "products": [ "species_10734755" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10734749": { "compartment": "compartment_13231", "id": "reaction_10734749", "reactome": "R-SPO-158441", "name": "Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733677" ], "products": [ "species_10734747" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10733679": { "compartment": "compartment_7660", "id": "reaction_10733679", "reactome": "R-SPO-77594", "name": "Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733165", "species_10733675", "species_10730903" ], "products": [ "species_10730621", "species_10733677", "species_10731317" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1921.03c", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "SPCC126.11c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10733226": { "compartment": "compartment_13231", "id": "reaction_10733226", "reactome": "R-SPO-75097", "name": "Transport of the export-competent mRNP complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733177" ], "products": [ "species_10733219" ], "modifiers": [ [ "species_10733155", "catalyst" ], [ "species_10733224", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "O94403", "SPCC126.11c", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "Q10267", "SPAC13G7.03", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9P383", "SPBC13A2.01c", "Q9URX8", "SPAC890.06", "Q10055", "SPAC1F5.10", "Q10168", "SPAC26A3.15c", "Q1MTR2", "SPBC13G1.14c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "O14253", "SPAC6G10.07", "Q09793", "SPAC22G7.09c", "P0CAN8", "SPAPB1A10.03", "O43044", "SPBC3B9.16c", "Q9Y8G3", "SPBC1921.03c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "O94403", "SPCC126.11c", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "Q10267", "SPAC13G7.03", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9P383", "SPBC13A2.01c", "Q9URX8", "SPAC890.06", "Q10055", "SPAC1F5.10", "Q10168", "SPAC26A3.15c", "Q1MTR2", "SPBC13G1.14c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "O14253", "SPAC6G10.07", "P0CAN8", "SPAPB1A10.03", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c", "SPBC31E1.05" ] }, "reaction_10734071": { "compartment": "compartment_7660", "id": "reaction_10734071", "reactome": "R-SPO-111439", "name": "Docking of Mature Histone mRNA complex:TAP at the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733165", "species_10730903", "species_10734067" ], "products": [ "species_10730621", "species_10734069" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1921.03c", "SPCC126.11c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10734761": { "compartment": "compartment_70101", "id": "reaction_10734761", "reactome": "R-SPO-158484", "name": "Release of the SLBP independent Histone mRNA from the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731794", "species_10734755" ], "products": [ "species_10734759", "species_10733187", "species_10733203" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1709.18", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "O74743", "SPBC1709.18", "SPBC1921.03c", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10734766": { "compartment": "compartment_7660", "id": "reaction_10734766", "reactome": "R-SPO-159101", "name": "NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733169", "species_10731417" ], "products": [ "species_113550", "species_10733175", "species_10734763" ], "modifiers": [ [ "species_10731417", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "P0CAN8", "SPAPB1A10.03", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "Q9P383", "SPBC13A2.01c", "C6Y4C0", "SPAC222.18", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "Q10267", "SPAC13G7.03", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q9Y8G3", "SPBC1921.03c", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "Q9USY2", "SPBC1861.04c", "Q10055", "SPAC1F5.10", "Q9Y7Y2", "SPBC365.05c", "Q1MTR2", "SPBC13G1.14c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "P0CAN8", "SPAPB1A10.03", "Q10267", "SPAC13G7.03", "species_29370", "O13792", "SPAC17G6.14c", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "Q9P383", "SPBC13A2.01c", "C6Y4C0", "SPAC222.18", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "Q10267", "SPAC13G7.03" ] }, "reaction_10734753": { "compartment": "compartment_70101", "id": "reaction_10734753", "reactome": "R-SPO-158447", "name": "Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731794", "species_10734747" ], "products": [ "species_10734751", "species_10733187", "species_10733203" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1709.18", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "O74743", "SPBC1709.18", "SPBC1921.03c", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10746231": { "compartment": "compartment_7660", "id": "reaction_10746231", "reactome": "R-SPO-5625784", "name": "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10746219" ], "products": [ "species_113582", "species_10746228" ], "modifiers": [ [ "species_10746219", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c" ] }, "reaction_10746240": { "compartment": "compartment_7660", "id": "reaction_10746240", "reactome": "R-SPO-5625796", "name": "Demethylase KDM4C binds KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746236", "species_10746228" ], "products": [ "species_10746238" ], "modifiers": [], "additional_components": [ "SPBC83.07", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "O94691", "SPBC83.07", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c" ] }, "reaction_10746249": { "compartment": "compartment_7660", "id": "reaction_10746249", "reactome": "R-SPO-5625797", "name": "KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10746238", "species_113685" ], "products": [ "species_10746236", "species_159942", "species_159939", "species_29478", "species_10746246" ], "modifiers": [ [ "species_10746238", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "O94691", "SPBC83.07", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "SPBC83.07", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "O94691", "SPBC83.07", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c" ] }, "reaction_10740388": { "compartment": "compartment_17957", "id": "reaction_10740388", "reactome": "R-SPO-901047", "name": "Binding of ERp57", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740236", "species_10740384" ], "products": [ "species_10740386" ], "modifiers": [], "additional_components": [ "SPAC1F5.02", "Q9P7D0", "SPBP4H10.19c", "P36581", "SPAC3C7.11c", "CHEBI:59080", "Q9P7D0", "SPBP4H10.19c", "P36581", "SPAC3C7.11c", "Q10057", "SPAC1F5.02", "CHEBI:59080" ] }, "reaction_10741489": { "compartment": "compartment_70101", "id": "reaction_10741489", "reactome": "R-SPO-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741485" ], "products": [ "species_10741487" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "CHEBI:59092", "CHEBI:60627", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "CHEBI:59087", "CHEBI:60629", "CHEBI:60628", "P0CH06", "SPAC11G7.04" ] }, "reaction_10750397": { "compartment": "compartment_1660541", "id": "reaction_10750397", "reactome": "R-SPO-6784738", "name": "Degradation of PCSK9:LDLR:Clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750393" ], "products": [ "species_10750391" ], "modifiers": [], "additional_components": [ "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P40903", "SPAC4A8.04", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10750395": { "compartment": "compartment_1660541", "id": "reaction_10750395", "reactome": "R-SPO-6784729", "name": "PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750361" ], "products": [ "species_10750393" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "P40903", "SPAC4A8.04", "Q9C0W7", "SPBC691.03c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P40903", "SPAC4A8.04" ] }, "reaction_10754372": { "compartment": "compartment_876", "id": "reaction_10754372", "reactome": "R-SPO-8855130", "name": "VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754362" ], "products": [ "species_10754370" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P40903", "SPAC4A8.04", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "P40903", "SPAC4A8.04", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10753477": { "compartment": "compartment_70101", "id": "reaction_10753477", "reactome": "R-SPO-6813720", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163579", "species_29356" ], "products": [ "species_216762", "species_8876730" ], "modifiers": [ [ "species_10753474", "catalyst" ] ], "additional_components": [ "Q9US38", "SPAPB1A11.02", "Q9HDX3", "SPAPB1A11.02" ] }, "reaction_10735593": { "compartment": "compartment_70101", "id": "reaction_10735593", "reactome": "R-SPO-174401", "name": "AHCY:NAD+ tetramer hydrolyses AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71285", "species_29356" ], "products": [ "species_174369", "species_83909" ], "modifiers": [ [ "species_10735590", "catalyst" ] ], "additional_components": [ "O13639", "SPBC8D2.18c", "species_113526" ] }, "reaction_10735568": { "compartment": "compartment_70101", "id": "reaction_10735568", "reactome": "R-SPO-174391", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174390", "species_29356" ], "products": [ "species_111294", "species_71284", "species_29372" ], "modifiers": [ [ "species_10735565", "catalyst" ] ], "additional_components": [ "O60198", "SPBC14F5.05c", "species_74126", "species_29926" ] }, "reaction_10752211": { "compartment": "compartment_70101", "id": "reaction_10752211", "reactome": "R-SPO-6800149", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806829", "species_71284" ], "products": [ "species_6800127", "species_71285" ], "modifiers": [ [ "species_10752205", "catalyst" ] ], "additional_components": [ "Q9UT94", "SPAC323.05c", "Q09723", "SPAC31A2.02" ] }, "reaction_10735665": { "compartment": "compartment_70101", "id": "reaction_10735665", "reactome": "R-SPO-175983", "name": "COMT transfer CH3 from AdoMet to 3,4DHBNZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_175977", "species_71284" ], "products": [ "species_71285", "species_175978" ], "modifiers": [ [ "species_10735662", "catalyst" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c" ] }, "reaction_10756481": { "compartment": "compartment_7660", "id": "reaction_10756481", "reactome": "R-SPO-8979071", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111793", "species_10743943" ], "products": [ "species_10743945" ], "modifiers": [], "additional_components": [ "SPBC23E6.09", "species_113531", "O60184", "SPBC23E6.09" ] }, "reaction_10743957": { "compartment": "compartment_70101", "id": "reaction_10743957", "reactome": "R-SPO-3225851", "name": "ROS oxidize thioredoxin and activate MAP3K5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1250243", "species_10743955" ], "products": [ "species_10732348", "species_10743953" ], "modifiers": [], "additional_components": [ "P28829", "SPBC1D7.05", "O94504", "SPBC12D12.07c", "SPBC12D12.07c", "SPBC1D7.05" ] }, "reaction_10739760": { "compartment": "compartment_70101", "id": "reaction_10739760", "reactome": "R-SPO-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739740" ], "products": [ "species_10739758" ], "modifiers": [], "additional_components": [ "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c" ] }, "reaction_10743960": { "compartment": "compartment_70101", "id": "reaction_10743960", "reactome": "R-SPO-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739826", "species_113592" ], "products": [ "species_29370", "species_10739740" ], "modifiers": [ [ "species_10743953", "catalyst" ] ], "additional_components": [ "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c", "SPBC1D7.05" ] }, "reaction_10743948": { "compartment": "compartment_7660", "id": "reaction_10743948", "reactome": "R-SPO-3222593", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743936", "species_113671" ], "products": [ "species_10743938", "species_159939" ], "modifiers": [ [ "species_10743945", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_113531", "O60184", "SPBC23E6.09" ] }, "reaction_10735519": { "compartment": "compartment_70101", "id": "reaction_10735519", "reactome": "R-SPO-174203", "name": "SCF-mediated degradation of Emi1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735512" ], "products": [ "species_10729165", "species_10735517", "species_10735506" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "Q9Y709", "SPBC409.05", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O13286", "SPAC144.13c", "P78972", "SPAC821.08c", "Q9Y709", "SPBC409.05", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10735515": { "compartment": "compartment_70101", "id": "reaction_10735515", "reactome": "R-SPO-174159", "name": "Ubiquitination of Emi1 by SCF-beta-TrCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729165", "species_10735510" ], "products": [ "species_10735512" ], "modifiers": [ [ "species_10735506", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9Y709", "SPBC409.05", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "Q9Y709", "SPBC409.05", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "P0CH06", "SPAC11G7.04", "Q9Y709", "SPBC409.05", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10734603": { "compartment": "compartment_70101", "id": "reaction_10734603", "reactome": "R-SPO-141429", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734592", "species_10734597" ], "products": [ "species_10734601" ], "modifiers": [], "additional_components": [ "SPAC821.08c", "SPBC20F10.06", "P78972", "SPAC821.08c", "O14417", "SPBC20F10.06" ] }, "reaction_10735495": { "compartment": "compartment_70101", "id": "reaction_10735495", "reactome": "R-SPO-174124", "name": "Dephosphorylation of phospho-Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735485", "species_29356" ], "products": [ "species_111294", "species_10735473" ], "modifiers": [ [ "species_10735492", "catalyst" ] ], "additional_components": [ "SPAC144.13c", "SPAC144.13c", "Q9P7H1", "SPAC1782.09c" ] }, "reaction_10734605": { "compartment": "compartment_70101", "id": "reaction_10734605", "reactome": "R-SPO-141437", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734592", "species_10734582", "species_10734597", "species_10734587" ], "products": [ "species_10734599" ], "modifiers": [], "additional_components": [ "SPAC821.08c", "SPCC1322.12c", "SPBC20F10.06", "SPAC23H3.08c", "O94751", "SPCC1322.12c", "P78972", "SPAC821.08c", "O42860", "SPAC23H3.08c", "O14417", "SPBC20F10.06" ] }, "reaction_10737618": { "compartment": "compartment_70101", "id": "reaction_10737618", "reactome": "R-SPO-264615", "name": "Loading of acetylcholine in synaptic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_372511", "species_264643", "species_10737613" ], "products": [ "species_70106", "species_10737615" ], "modifiers": [ [ "species_10737597", "catalyst" ] ], "additional_components": [ "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "species_264643", "SPCC18.02" ] }, "reaction_10754876": { "compartment": "compartment_70101", "id": "reaction_10754876", "reactome": "R-SPO-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10754873", "catalyst" ] ], "additional_components": [ "O13944", "SPAC23H4.01c", "O74178", "SPBC1271.12", "O14340", "SPBC2F12.05c" ] }, "reaction_10736277": { "compartment": "compartment_70101", "id": "reaction_10736277", "reactome": "R-SPO-193816", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192194", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193835" ], "modifiers": [ [ "species_10736206", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736267": { "compartment": "compartment_70101", "id": "reaction_10736267", "reactome": "R-SPO-193755", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193745" ], "products": [ "species_29366", "species_193707" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736273": { "compartment": "compartment_70101", "id": "reaction_10736273", "reactome": "R-SPO-193789", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192189", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193724" ], "modifiers": [ [ "species_10736206", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10755031": { "compartment": "compartment_70101", "id": "reaction_10755031", "reactome": "R-SPO-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_1806234", "species_8868393" ], "modifiers": [ [ "species_10755028", "catalyst" ] ], "additional_components": [ "O13944", "SPAC23H4.01c", "O14340", "SPBC2F12.05c" ] }, "reaction_10736211": { "compartment": "compartment_70101", "id": "reaction_10736211", "reactome": "R-SPO-192160", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191980" ], "products": [ "species_29366", "species_192030" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736201": { "compartment": "compartment_70101", "id": "reaction_10736201", "reactome": "R-SPO-192067", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192195" ], "products": [ "species_29366", "species_192064" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736269": { "compartment": "compartment_70101", "id": "reaction_10736269", "reactome": "R-SPO-193758", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193760" ], "products": [ "species_29366", "species_213285" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736199": { "compartment": "compartment_70101", "id": "reaction_10736199", "reactome": "R-SPO-192036", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192064" ], "products": [ "species_29366", "species_192087" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736275": { "compartment": "compartment_70101", "id": "reaction_10736275", "reactome": "R-SPO-193800", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193829" ], "products": [ "species_29366", "species_193843" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736209": { "compartment": "compartment_70101", "id": "reaction_10736209", "reactome": "R-SPO-192097", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192114", "species_29360" ], "products": [ "species_70106", "species_73473", "species_192136" ], "modifiers": [ [ "species_10736206", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736283": { "compartment": "compartment_70101", "id": "reaction_10736283", "reactome": "R-SPO-193841", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193830" ], "products": [ "species_29366", "species_193842" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736279": { "compartment": "compartment_70101", "id": "reaction_10736279", "reactome": "R-SPO-193821", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_9617026", "species_29364" ], "products": [ "species_29366", "species_193829" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736271": { "compartment": "compartment_70101", "id": "reaction_10736271", "reactome": "R-SPO-193781", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193707" ], "products": [ "species_29366", "species_193728" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736188": { "compartment": "compartment_70101", "id": "reaction_10736188", "reactome": "R-SPO-192033", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192136" ], "products": [ "species_29366", "species_191980" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736168": { "compartment": "compartment_70101", "id": "reaction_10736168", "reactome": "R-SPO-191983", "name": "Cholesterol is hydroxylated to 25-hydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_176478", "species_29368" ], "products": [ "species_29366", "species_192148", "species_29356" ], "modifiers": [ [ "species_10736165", "catalyst" ] ], "additional_components": [ "species_113531", "Q9UUH4", "SPAC630.08c" ] }, "reaction_10736265": { "compartment": "compartment_70101", "id": "reaction_10736265", "reactome": "R-SPO-193746", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193724" ], "products": [ "species_29366", "species_193760" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736281": { "compartment": "compartment_70101", "id": "reaction_10736281", "reactome": "R-SPO-193824", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193835", "species_29364" ], "products": [ "species_29366", "species_193830" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736263": { "compartment": "compartment_876", "id": "reaction_10736263", "reactome": "R-SPO-193362", "name": "ABCB11 transports bile salts from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193416", "species_113592", "species_29356" ], "products": [ "species_29370", "species_193479", "species_29372" ], "modifiers": [ [ "species_10736260", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "CHEBI:16525", "CHEBI:28865", "CHEBI:36274", "CHEBI:17687", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274", "Q02592", "SPCC737.09c", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10756980": { "compartment": "compartment_70101", "id": "reaction_10756980", "reactome": "R-SPO-9020257", "name": "LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024893", "species_29356" ], "products": [ "species_9024879" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10757026": { "compartment": "compartment_70101", "id": "reaction_10757026", "reactome": "R-SPO-9024890", "name": "LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024873" ], "products": [ "species_9024886" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10734197": { "compartment": "compartment_12045", "id": "reaction_10734197", "reactome": "R-SPO-111883", "name": "Hydrolysis of phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_140356", "species_428981" ], "modifiers": [ [ "species_10734192", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "species_429785", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10756212": { "compartment": "compartment_70101", "id": "reaction_10756212", "reactome": "R-SPO-8951727", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734228", "species_30389" ], "products": [ "species_10734230" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "P40376", "SPBC106.10", "P36600", "SPAC8C9.03", "species_30389", "P40376", "SPBC106.10" ] }, "reaction_10735214": { "compartment": "compartment_947587", "id": "reaction_10735214", "reactome": "R-SPO-167415", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734141", "species_29420" ], "products": [ "species_29438", "species_10734240" ], "modifiers": [ [ "species_10734135", "catalyst" ] ], "additional_components": [ "species_29438", "Q04665", "SPAC23H3.13c", "species_29420", "Q04665", "SPAC23H3.13c", "SPAC23H3.13c" ] }, "reaction_10734214": { "compartment": "compartment_70101", "id": "reaction_10734214", "reactome": "R-SPO-111898", "name": "Phosphorylation of cPLA2 by ERK-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734211" ], "products": [ "species_29370", "species_10734190" ], "modifiers": [ [ "species_10733808", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "SPAC31G5.09c" ] }, "reaction_10734146": { "compartment": "compartment_70101", "id": "reaction_10734146", "reactome": "R-SPO-111879", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10734143", "catalyst" ] ], "additional_components": [ "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c" ] }, "reaction_10734242": { "compartment": "compartment_70101", "id": "reaction_10734242", "reactome": "R-SPO-112037", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734143", "species_29356" ], "products": [ "species_10734124", "species_29372", "species_10734240" ], "modifiers": [], "additional_components": [ "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c", "SPAC22F8.11", "species_29420", "Q04665", "SPAC23H3.13c" ] }, "reaction_10739391": { "compartment": "compartment_70101", "id": "reaction_10739391", "reactome": "R-SPO-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10739383" ], "products": [ "species_113582", "species_10739388" ], "modifiers": [ [ "species_10739383", "catalyst" ] ], "additional_components": [ "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05" ] }, "reaction_10734194": { "compartment": "compartment_70101", "id": "reaction_10734194", "reactome": "R-SPO-111881", "name": "Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_10734190", "species_74016" ], "products": [ "species_10734192" ], "modifiers": [], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "species_429785", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10734234": { "compartment": "compartment_70101", "id": "reaction_10734234", "reactome": "R-SPO-111925", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734230" ], "products": [ "species_10734226", "species_10734232" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "species_30389", "P40376", "SPBC106.10", "SPBC106.10", "P36600", "SPAC8C9.03", "species_30389" ] }, "reaction_10738861": { "compartment": "compartment_70101", "id": "reaction_10738861", "reactome": "R-SPO-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426030", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10738858", "catalyst" ] ], "additional_components": [ "SPCC5E4.05c" ] }, "reaction_10749913": { "compartment": "compartment_876", "id": "reaction_10749913", "reactome": "R-SPO-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694509", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10749910", "catalyst" ] ], "additional_components": [ "SPAC22H12.03" ] }, "reaction_10743111": { "compartment": "compartment_70101", "id": "reaction_10743111", "reactome": "R-SPO-2408551", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5357707", "species_29356" ], "products": [ "species_5357652", "species_111294", "species_29372" ], "modifiers": [ [ "species_10735565", "catalyst" ] ], "additional_components": [ "O60198", "SPBC14F5.05c", "species_74126", "species_29926" ] }, "reaction_10756166": { "compartment": "compartment_70616", "id": "reaction_10756166", "reactome": "R-SPO-8949688", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8949220", "species_2889072" ], "products": [ "species_8949232", "species_2889083" ], "modifiers": [ [ "species_10756163", "catalyst" ] ], "additional_components": [ "SPAC3A12.06c" ] }, "reaction_10729369": { "compartment": "compartment_70101", "id": "reaction_10729369", "reactome": "R-SPO-68948", "name": "Ubiquitinated Orc1 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729071" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "SPBC29A10.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10729069": { "compartment": "compartment_7660", "id": "reaction_10729069", "reactome": "R-SPO-68946", "name": "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728907", "species_10729044" ], "products": [ "species_10729047" ], "modifiers": [ [ "species_10729066", "catalyst" ] ], "additional_components": [ "SPBC29A10.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC29A10.15", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12" ] }, "reaction_10728940": { "compartment": "compartment_7660", "id": "reaction_10728940", "reactome": "R-SPO-68944", "name": "Orc1 is phosphorylated by cyclin A/CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10728897" ], "products": [ "species_113582", "species_10728907", "species_10728911" ], "modifiers": [ [ "species_10728937", "catalyst" ] ], "additional_components": [ "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "SPBC29A10.15", "Q9Y794", "SPBP23A10.13", "O43114", "SPBC646.14c", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P41411", "SPBC14C8.07c", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "O74796", "SPBC2A9.12", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10729409": { "compartment": "compartment_7660", "id": "reaction_10729409", "reactome": "R-SPO-69005", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728714", "species_29358" ], "products": [ "species_113582", "species_10729384" ], "modifiers": [ [ "species_10729406", "catalyst" ] ], "additional_components": [ "SPBC14C8.07c", "SPBC14C8.07c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10729419": { "compartment": "compartment_70101", "id": "reaction_10729419", "reactome": "R-SPO-69016", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729417" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P41411", "SPBC14C8.07c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10729421": { "compartment": "compartment_7660", "id": "reaction_10729421", "reactome": "R-SPO-69019", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728861" ], "products": [ "species_10728857", "species_10728852", "species_10728828", "species_10728845" ], "modifiers": [], "additional_components": [ "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "SPAC1B2.05", "SPCC1682.02c", "SPBC4.04c", "P29458", "SPCC16A11.17", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10729073": { "compartment": "compartment_7660", "id": "reaction_10729073", "reactome": "R-SPO-68947", "name": "Ubiquitinated Orc1 enters the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729047" ], "products": [ "species_10729071" ], "modifiers": [], "additional_components": [ "SPBC29A10.15", "SPBC29A10.15" ] }, "reaction_10729413": { "compartment": "compartment_7660", "id": "reaction_10729413", "reactome": "R-SPO-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729384" ], "products": [ "species_10729411" ], "modifiers": [], "additional_components": [ "SPBC14C8.07c", "SPBC14C8.07c" ] }, "reaction_10736391": { "compartment": "compartment_70101", "id": "reaction_10736391", "reactome": "R-SPO-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73524", "species_113592" ], "products": [ "species_29386", "species_111294" ], "modifiers": [ [ "species_10736388", "catalyst" ] ], "additional_components": [ "SPCC1235.04c" ] }, "reaction_10736411": { "compartment": "compartment_70101", "id": "reaction_10736411", "reactome": "R-SPO-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10736408", "catalyst" ] ], "additional_components": [ "O74866", "SPCC18.16c", "species_29926" ] }, "reaction_10736401": { "compartment": "compartment_70101", "id": "reaction_10736401", "reactome": "R-SPO-196955", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29386", "species_29356" ], "products": [ "species_73524", "species_76577" ], "modifiers": [ [ "species_10736398", "catalyst" ] ], "additional_components": [ "O94323", "SPBC725.05c" ] }, "reaction_10738598": { "compartment": "compartment_876", "id": "reaction_10738598", "reactome": "R-SPO-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10738589", "catalyst" ] ], "additional_components": [ "SPAPB2B4.04c" ] }, "reaction_10746051": { "compartment": "compartment_876", "id": "reaction_10746051", "reactome": "R-SPO-5617178", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738595", "species_10738606" ], "products": [ "species_10746049" ], "modifiers": [], "additional_components": [ "SPAPB2B4.04c", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "Q9HDW7", "SPAPB2B4.04c", "P36587", "SPBC29A10.01" ] }, "reaction_10745982": { "compartment": "compartment_70101", "id": "reaction_10745982", "reactome": "R-SPO-5607721", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738454" ], "products": [ "species_10738454" ], "modifiers": [], "additional_components": [ "SPAC1006.09", "SPAC1006.09" ] }, "reaction_10746751": { "compartment": "compartment_70101", "id": "reaction_10746751", "reactome": "R-SPO-5668545", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10738454" ], "products": [ "species_29370", "species_10746748" ], "modifiers": [ [ "species_10738454", "catalyst" ] ], "additional_components": [ "SPAC1006.09", "SPAC1006.09", "SPAC1006.09" ] }, "reaction_10739639": { "compartment": "compartment_70101", "id": "reaction_10739639", "reactome": "R-SPO-446877", "name": "TRAF6 is K63 poly-ubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739630" ], "products": [ "species_10739636" ], "modifiers": [ [ "species_10739630", "catalyst" ] ], "additional_components": [ "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "O13924", "SPAC23C4.03", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746745": { "compartment": "compartment_70101", "id": "reaction_10746745", "reactome": "R-SPO-5668520", "name": "26Sproteasome degrades K48polyUb-NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746743" ], "products": [], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "SPAC1006.09", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10735267": { "compartment": "compartment_7660", "id": "reaction_10735267", "reactome": "R-SPO-168053", "name": "Phosphorylated MAPKs phosphorylate ATF-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10735231" ], "products": [ "species_113582", "species_10735245" ], "modifiers": [ [ "species_10735264", "catalyst" ] ], "additional_components": [ "P52890", "SPBC29B5.01", "P78962", "SPBC2F12.09c", "Q09771", "SPAC22F3.02", "P52890", "SPBC29B5.01", "P78962", "SPBC2F12.09c", "Q09771", "SPAC22F3.02", "Q09892", "SPAC24B11.06c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10739950": { "compartment": "compartment_70101", "id": "reaction_10739950", "reactome": "R-SPO-451418", "name": "Pellino ubiquitinates IRAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739939" ], "products": [ "species_10739947" ], "modifiers": [ [ "species_10739939", "catalyst" ] ], "additional_components": [ "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "O13924", "SPAC23C4.03", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10736765": { "compartment": "compartment_7660", "id": "reaction_10736765", "reactome": "R-SPO-199959", "name": "ERKs are inactivated by protein phosphatase 2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10736632" ], "products": [ "species_113550", "species_10736739" ], "modifiers": [ [ "species_10736762", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "Q10428", "SPCC188.02", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c" ] }, "reaction_10736635": { "compartment": "compartment_7660", "id": "reaction_10736635", "reactome": "R-SPO-198756", "name": "ERK1/2 phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10736617" ], "products": [ "species_113582", "species_10736623" ], "modifiers": [ [ "species_10736632", "catalyst" ] ], "additional_components": [ "SPCC4G3.08", "SPCC4G3.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10737238": { "compartment": "compartment_7660", "id": "reaction_10737238", "reactome": "R-SPO-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10736632" ], "products": [ "species_113550", "species_10736739" ], "modifiers": [ [ "species_10737231", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPBC1685.01" ] }, "reaction_10736626": { "compartment": "compartment_7660", "id": "reaction_10736626", "reactome": "R-SPO-198669", "name": "p38MAPK phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10736617" ], "products": [ "species_113582", "species_10736623" ], "modifiers": [ [ "species_10735252", "catalyst" ] ], "additional_components": [ "SPCC4G3.08", "SPCC4G3.08", "SPAC24B11.06c" ] }, "reaction_10739512": { "compartment": "compartment_12045", "id": "reaction_10739512", "reactome": "R-SPO-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449221", "species_110614" ], "products": [ "species_449299", "species_110094" ], "modifiers": [ [ "species_10739509", "catalyst" ] ], "additional_components": [ "SPCC63.10c" ] }, "reaction_10744801": { "compartment": "compartment_12045", "id": "reaction_10744801", "reactome": "R-SPO-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_4419981" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10744798", "catalyst" ] ], "additional_components": [ "SPAC7D4.09c" ] }, "reaction_10739528": { "compartment": "compartment_12045", "id": "reaction_10739528", "reactome": "R-SPO-446200", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449744", "species_29356" ], "products": [ "species_449299", "species_29372" ], "modifiers": [ [ "species_10739525", "catalyst" ] ], "additional_components": [ "SPBC530.12c" ] }, "reaction_10736144": { "compartment": "compartment_70101", "id": "reaction_10736144", "reactome": "R-SPO-191414", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191403" ], "products": [ "species_29370", "species_191362", "species_113528", "species_29372" ], "modifiers": [ [ "species_10736141", "catalyst" ] ], "additional_components": [ "O13963", "SPAC24C9.03" ] }, "reaction_10744793": { "compartment": "compartment_12045", "id": "reaction_10744793", "reactome": "R-SPO-4419978", "name": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419987", "species_191362" ], "products": [ "species_4419982" ], "modifiers": [ [ "species_10744790", "catalyst" ] ], "additional_components": [ "O14171", "SPAC4D7.04c", "Q9Y7K8", "SPBC2A9.06c" ] }, "reaction_10739410": { "compartment": "compartment_70101", "id": "reaction_10739410", "reactome": "R-SPO-445079", "name": "Phosphorylation of L1 by ERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738464", "species_113592", "species_10733808" ], "products": [ "species_29370", "species_10739408" ], "modifiers": [ [ "species_10733808", "catalyst" ] ], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "SPAC31G5.09c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "P27638", "SPAC31G5.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "SPAC31G5.09c" ] }, "reaction_10733813": { "compartment": "compartment_70101", "id": "reaction_10733813", "reactome": "R-SPO-109862", "name": "MAP2K2 phosphorylates MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10733780" ], "products": [ "species_29370", "species_10733810" ], "modifiers": [ [ "species_10733780", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13" ] }, "reaction_10738466": { "compartment": "compartment_17940", "id": "reaction_10738466", "reactome": "R-SPO-392749", "name": "Transport of L1 into endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738464" ], "products": [ "species_10738464" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10733803": { "compartment": "compartment_70101", "id": "reaction_10733803", "reactome": "R-SPO-109860", "name": "MAP2K1 phosphorylates MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10733770" ], "products": [ "species_29370", "species_10733794" ], "modifiers": [ [ "species_10733770", "catalyst" ], [ "species_10733799", "inhibitor" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "SPAC1D4.13" ] }, "reaction_10740265": { "compartment": "compartment_876", "id": "reaction_10740265", "reactome": "R-SPO-555065", "name": "Formation of clathrin coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735803", "species_29438", "species_10740252" ], "products": [ "species_10738464", "species_29372", "species_29420" ], "modifiers": [ [ "species_10740262", "catalyst" ] ], "additional_components": [ "SPBC119.05c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c" ] }, "reaction_10742224": { "compartment": "compartment_70101", "id": "reaction_10742224", "reactome": "R-SPO-1614583", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614518", "species_29356" ], "products": [ "species_29382", "species_936714", "species_111707" ], "modifiers": [ [ "species_10742218", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10744044": { "compartment": "compartment_70101", "id": "reaction_10744044", "reactome": "R-SPO-3299753", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744037" ], "products": [ "species_10744041", "species_10744022" ], "modifiers": [ [ "species_10744037", "catalyst" ] ], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "P28758", "SPAC821.10c", "species_442320", "species_437295", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552" ] }, "reaction_10744457": { "compartment": "compartment_70101", "id": "reaction_10744457", "reactome": "R-SPO-3697882", "name": "PRDX5 reduces peroxynitrite to nitrite using TXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222481", "species_10732350" ], "products": [ "species_10732348", "species_29356", "species_1222379" ], "modifiers": [ [ "species_10744099", "catalyst" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "SPCC330.06c" ] }, "reaction_10744104": { "compartment": "compartment_70101", "id": "reaction_10744104", "reactome": "R-SPO-3341343", "name": "PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29408", "species_10732350" ], "products": [ "species_10732348", "species_29356" ], "modifiers": [ [ "species_10744101", "catalyst" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "O14313", "SPCC330.06c", "O74887", "SPCC576.03c" ] }, "reaction_10744454": { "compartment": "compartment_70101", "id": "reaction_10744454", "reactome": "R-SPO-3697860", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744035", "species_10744450" ], "products": [ "species_10744452" ], "modifiers": [], "additional_components": [ "species_442320", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552" ] }, "reaction_10756210": { "compartment": "compartment_70101", "id": "reaction_10756210", "reactome": "R-SPO-8951723", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744452" ], "products": [ "species_10744037" ], "modifiers": [], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552" ] }, "reaction_10744025": { "compartment": "compartment_70101", "id": "reaction_10744025", "reactome": "R-SPO-3299691", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_1222424" ], "products": [ "species_29408", "species_29368" ], "modifiers": [ [ "species_10744022", "catalyst" ] ], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "species_437295" ] }, "reaction_10744083": { "compartment": "compartment_70616", "id": "reaction_10744083", "reactome": "R-SPO-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10734930" ], "products": [ "species_189461", "species_10734928" ], "modifiers": [], "additional_components": [ "P00046", "SPCC191.07", "CHEBI:38574", "P00046", "SPCC191.07", "CHEBI:38573" ] }, "reaction_10744079": { "compartment": "compartment_5460", "id": "reaction_10744079", "reactome": "R-SPO-3323079", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_1655882", "species_113529" ], "products": [ "species_113563", "species_1655887" ], "modifiers": [ [ "species_10744076", "catalyst" ] ], "additional_components": [ "P78965", "SPBC17A3.07", "species_113596" ] }, "reaction_10744015": { "compartment": "compartment_984", "id": "reaction_10744015", "reactome": "R-SPO-3299682", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299686", "species_351626" ], "products": [ "species_351629", "species_352327" ], "modifiers": [ [ "species_10744012", "catalyst" ] ], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "species_437295" ] }, "reaction_10744004": { "compartment": "compartment_5460", "id": "reaction_10744004", "reactome": "R-SPO-3299680", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299683", "species_113529" ], "products": [ "species_113533", "species_1614617" ], "modifiers": [ [ "species_10744001", "catalyst" ] ], "additional_components": [ "Q9UQX0", "SPAC1486.01", "species_113527" ] }, "reaction_10733436": { "compartment": "compartment_17951", "id": "reaction_10733436", "reactome": "R-SPO-76031", "name": "2 H2O2 => O2 + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113575" ], "products": [ "species_141343", "species_113535" ], "modifiers": [ [ "species_10733433", "catalyst" ] ], "additional_components": [ "species_189444", "P55306", "SPCC757.07c", "species_113600" ] }, "reaction_10744568": { "compartment": "compartment_17927", "id": "reaction_10744568", "reactome": "R-SPO-3777112", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_163953" ], "products": [ "species_189481", "species_189461" ], "modifiers": [ [ "species_10744565", "catalyst" ] ], "additional_components": [ "species_442320", "P28758", "SPAC821.10c", "species_437295" ] }, "reaction_10745062": { "compartment": "compartment_17963", "id": "reaction_10745062", "reactome": "R-SPO-4837364", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745060" ], "products": [ "species_10744012" ], "modifiers": [], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "species_437295", "P28758", "SPAC821.10c", "species_442320", "species_437295" ] }, "reaction_10746853": { "compartment": "compartment_70101", "id": "reaction_10746853", "reactome": "R-SPO-5674385", "name": "p-T,Y MAPKs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741495" ], "products": [ "species_10744304" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10757290": { "compartment": "compartment_70101", "id": "reaction_10757290", "reactome": "R-SPO-9610166", "name": "p-T,Y MAPK dimers translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744304" ], "products": [ "species_10736632" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10739876": { "compartment": "compartment_70101", "id": "reaction_10739876", "reactome": "R-SPO-450517", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739853", "species_450523" ], "products": [ "species_10739855" ], "modifiers": [], "additional_components": [ "SPBC1718.07c", "P47979", "SPBC1718.07c" ] }, "reaction_10739870": { "compartment": "compartment_70101", "id": "reaction_10739870", "reactome": "R-SPO-450490", "name": "Protein Kinase B/Akt phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739855", "species_113592" ], "products": [ "species_29370", "species_10739867" ], "modifiers": [ [ "species_10736495", "catalyst" ] ], "additional_components": [ "P47979", "SPBC1718.07c", "P47979", "SPBC1718.07c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10738965": { "compartment": "compartment_876", "id": "reaction_10738965", "reactome": "R-SPO-427570", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10738962", "catalyst" ] ], "additional_components": [ "O59782", "SPCC320.05" ] }, "reaction_10738848": { "compartment": "compartment_171062", "id": "reaction_10738848", "reactome": "R-SPO-425983", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425978", "species_83910" ], "products": [ "species_70106", "species_425971" ], "modifiers": [ [ "species_10738845", "catalyst" ] ], "additional_components": [ "O13726", "SPAC15A10.06" ] }, "reaction_10738839": { "compartment": "compartment_172574", "id": "reaction_10738839", "reactome": "R-SPO-425965", "name": "SLC9A9 exchanges Na+ for H+ across the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83910", "species_425999" ], "products": [ "species_70106", "species_425977" ], "modifiers": [ [ "species_10738836", "catalyst" ] ], "additional_components": [ "SPAC15A10.06" ] }, "reaction_10746330": { "compartment": "compartment_70101", "id": "reaction_10746330", "reactome": "R-SPO-5627802", "name": "SLC26A4 transports I- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209785" ], "products": [ "species_209818" ], "modifiers": [ [ "species_10746327", "catalyst" ] ], "additional_components": [ "SPCC320.05" ] }, "reaction_10738878": { "compartment": "compartment_876", "id": "reaction_10738878", "reactome": "R-SPO-426130", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972" ], "products": [ "species_83910", "species_352022" ], "modifiers": [ [ "species_10738875", "catalyst" ] ], "additional_components": [ "SPBC18H10.16" ] }, "reaction_10754356": { "compartment": "compartment_70101", "id": "reaction_10754356", "reactome": "R-SPO-8855062", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162252", "species_71284" ], "products": [ "species_71285", "species_2162265" ], "modifiers": [ [ "species_10754353", "catalyst" ] ], "additional_components": [ "SPAC12B10.09" ] }, "reaction_10738984": { "compartment": "compartment_17938", "id": "reaction_10738984", "reactome": "R-SPO-428007", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427984", "species_428040" ], "products": [ "species_70106", "species_428003" ], "modifiers": [ [ "species_10738979", "catalyst" ] ], "additional_components": [ "CHEBI:90799", "CHEBI:32513", "CHEBI:32513", "CHEBI:46761", "SPBC13A2.04c" ] }, "reaction_10738956": { "compartment": "compartment_876", "id": "reaction_10738956", "reactome": "R-SPO-427555", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648", "species_351626" ], "products": [ "species_70106", "species_174375" ], "modifiers": [ [ "species_10738953", "catalyst" ] ], "additional_components": [ "O59782", "SPCC320.05" ] }, "reaction_10755472": { "compartment": "compartment_70101", "id": "reaction_10755472", "reactome": "R-SPO-8875623", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29404" ], "products": [ "species_113552", "species_113529" ], "modifiers": [ [ "species_10755469", "catalyst" ] ], "additional_components": [ "Q9P3T7", "SPAC328.09" ] }, "reaction_10755488": { "compartment": "compartment_70101", "id": "reaction_10755488", "reactome": "R-SPO-8875871", "name": "SLC26A11 transports SO4(2-) from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648" ], "products": [ "species_174375" ], "modifiers": [ [ "species_10755485", "catalyst" ] ], "additional_components": [ "SPAC869.05c" ] }, "reaction_10738819": { "compartment": "compartment_876", "id": "reaction_10738819", "reactome": "R-SPO-425822", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_425815" ], "products": [ "species_425810", "species_74112" ], "modifiers": [ [ "species_10738816", "catalyst" ] ], "additional_components": [ "SPAC3A12.06c" ] }, "reaction_10738974": { "compartment": "compartment_876", "id": "reaction_10738974", "reactome": "R-SPO-427666", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627", "species_188972" ], "products": [ "species_352022", "species_425425" ], "modifiers": [ [ "species_10738971", "catalyst" ] ], "additional_components": [ "O59782", "SPCC320.05" ] }, "reaction_10738873": { "compartment": "compartment_876", "id": "reaction_10738873", "reactome": "R-SPO-426086", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972", "species_74126" ], "products": [ "species_29804", "species_83910", "species_352022" ], "modifiers": [ [ "species_10738870", "catalyst" ] ], "additional_components": [ "O60146", "SPBC18H10.16" ] }, "reaction_10738853": { "compartment": "compartment_20699", "id": "reaction_10738853", "reactome": "R-SPO-426015", "name": "Na+/H+ exchanger transport (at trans-golgi membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425969", "species_83910" ], "products": [ "species_70106", "species_425958" ], "modifiers": [ [ "species_10738850", "catalyst" ] ], "additional_components": [ "SPAC15A10.06" ] }, "reaction_10753176": { "compartment": "compartment_70101", "id": "reaction_10753176", "reactome": "R-SPO-6809778", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809774", "species_29356" ], "products": [ "species_422529", "species_29372" ], "modifiers": [ [ "species_10753168", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10753572": { "compartment": "compartment_876", "id": "reaction_10753572", "reactome": "R-SPO-6814797", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2239407" ], "products": [ "species_6814794", "species_6814795" ], "modifiers": [ [ "species_10753569", "catalyst" ] ], "additional_components": [ "SPBC725.05c" ] }, "reaction_10753131": { "compartment": "compartment_70101", "id": "reaction_10753131", "reactome": "R-SPO-6809254", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753127", "species_10753125" ], "products": [ "species_10753129" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742441": { "compartment": "compartment_876", "id": "reaction_10742441", "reactome": "R-SPO-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10742438", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "O13819", "SPAC19A8.03" ] }, "reaction_10753468": { "compartment": "compartment_7660", "id": "reaction_10753468", "reactome": "R-SPO-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_6810408" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10753465", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14" ] }, "reaction_10742467": { "compartment": "compartment_12045", "id": "reaction_10742467", "reactome": "R-SPO-1676124", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806234", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10742464", "catalyst" ] ], "additional_components": [ "SPBC19F5.03" ] }, "reaction_10753148": { "compartment": "compartment_876", "id": "reaction_10753148", "reactome": "R-SPO-6809320", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10753145", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742498": { "compartment": "compartment_20699", "id": "reaction_10742498", "reactome": "R-SPO-1676185", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10742495", "catalyst" ] ], "additional_components": [ "Q9UT42", "SPAC343.19", "Q9USR3", "SPBC577.06c" ] }, "reaction_10742443": { "compartment": "compartment_172574", "id": "reaction_10742443", "reactome": "R-SPO-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_29370", "species_1806198" ], "modifiers": [ [ "species_10742410", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "species_113527" ] }, "reaction_10742425": { "compartment": "compartment_20699", "id": "reaction_10742425", "reactome": "R-SPO-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10742410", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "species_113527" ] }, "reaction_10753515": { "compartment": "compartment_12045", "id": "reaction_10753515", "reactome": "R-SPO-6814254", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6814253", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10753512", "catalyst" ] ], "additional_components": [ "SPCC4B3.04c" ] }, "reaction_10753151": { "compartment": "compartment_876", "id": "reaction_10753151", "reactome": "R-SPO-6809325", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10753145", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742449": { "compartment": "compartment_876", "id": "reaction_10742449", "reactome": "R-SPO-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742382": { "compartment": "compartment_12045", "id": "reaction_10742382", "reactome": "R-SPO-1675813", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_29370", "species_1806234" ], "modifiers": [ [ "species_10742379", "catalyst" ] ], "additional_components": [ "Q9UT42", "SPAC343.19", "Q9USR3", "SPBC577.06c" ] }, "reaction_10742353": { "compartment": "compartment_876", "id": "reaction_10742353", "reactome": "R-SPO-1675780", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_392417" ], "modifiers": [ [ "species_10742348", "catalyst" ] ], "additional_components": [ "SPAC343.19" ] }, "reaction_10742476": { "compartment": "compartment_171062", "id": "reaction_10742476", "reactome": "R-SPO-1676141", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10742451", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10753164": { "compartment": "compartment_171062", "id": "reaction_10753164", "reactome": "R-SPO-6809720", "name": "PI3P is dephosphorylated to PI by MTM1:MTMR12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10753155", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742473": { "compartment": "compartment_876", "id": "reaction_10742473", "reactome": "R-SPO-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_1806224" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742423": { "compartment": "compartment_876", "id": "reaction_10742423", "reactome": "R-SPO-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_29356" ], "products": [ "species_202247", "species_29372" ], "modifiers": [ [ "species_10742418", "catalyst" ] ], "additional_components": [ "SPBC577.13" ] }, "reaction_10753157": { "compartment": "compartment_70101", "id": "reaction_10753157", "reactome": "R-SPO-6809680", "name": "MTMR12 binds MTM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753153", "species_10742358" ], "products": [ "species_10753155" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742462": { "compartment": "compartment_20699", "id": "reaction_10742462", "reactome": "R-SPO-1676114", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806159", "species_29356" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10742459", "catalyst" ] ], "additional_components": [ "SPBC19F5.03" ] }, "reaction_10742488": { "compartment": "compartment_20699", "id": "reaction_10742488", "reactome": "R-SPO-1676152", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742486", "species_10742399" ], "products": [ "species_10742401" ], "modifiers": [], "additional_components": [ "SPAC22E12.16c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "P36579", "SPBC4F6.18c", "Q10366", "SPAC22E12.16c", "CHEBI:15996" ] }, "reaction_10742508": { "compartment": "compartment_20699", "id": "reaction_10742508", "reactome": "R-SPO-1676204", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806230", "species_29356" ], "products": [ "species_1806217", "species_29372" ], "modifiers": [ [ "species_10742503", "catalyst" ] ], "additional_components": [ "SPBC609.02" ] }, "reaction_10742454": { "compartment": "compartment_171062", "id": "reaction_10742454", "reactome": "R-SPO-1676105", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806205", "species_29356" ], "products": [ "species_1806259", "species_29372" ], "modifiers": [ [ "species_10742451", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742501": { "compartment": "compartment_876", "id": "reaction_10742501", "reactome": "R-SPO-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10742438", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "O13819", "SPAC19A8.03" ] }, "reaction_10753170": { "compartment": "compartment_70101", "id": "reaction_10753170", "reactome": "R-SPO-6809764", "name": "SBF1 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742360", "species_10753166" ], "products": [ "species_10753168" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742484": { "compartment": "compartment_876", "id": "reaction_10742484", "reactome": "R-SPO-1676149", "name": "PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_202247", "species_29356" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10736691", "catalyst" ] ], "additional_components": [ "SPBC609.02" ] }, "reaction_10742481": { "compartment": "compartment_876", "id": "reaction_10742481", "reactome": "R-SPO-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10742478", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14" ] }, "reaction_10742430": { "compartment": "compartment_876", "id": "reaction_10742430", "reactome": "R-SPO-1675988", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_392417" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10742387", "catalyst" ] ], "additional_components": [ "SPBC2G2.02" ] }, "reaction_10742320": { "compartment": "compartment_876", "id": "reaction_10742320", "reactome": "R-SPO-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_29370", "species_179838" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742404": { "compartment": "compartment_20699", "id": "reaction_10742404", "reactome": "R-SPO-1675883", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10742401", "catalyst" ] ], "additional_components": [ "P36579", "SPBC4F6.18c", "Q10366", "SPAC22E12.16c", "CHEBI:15996" ] }, "reaction_10736694": { "compartment": "compartment_70101", "id": "reaction_10736694", "reactome": "R-SPO-199456", "name": "PTEN dephosphorylates PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_29356" ], "products": [ "species_29372", "species_179856" ], "modifiers": [ [ "species_10736691", "catalyst" ] ], "additional_components": [ "SPBC609.02" ] }, "reaction_10742446": { "compartment": "compartment_172574", "id": "reaction_10742446", "reactome": "R-SPO-1676065", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806289" ], "products": [ "species_1806212", "species_29372" ], "modifiers": [ [ "species_10742366", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742392": { "compartment": "compartment_876", "id": "reaction_10742392", "reactome": "R-SPO-1675836", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10742387", "catalyst" ] ], "additional_components": [ "SPBC2G2.02" ] }, "reaction_10742372": { "compartment": "compartment_876", "id": "reaction_10742372", "reactome": "R-SPO-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_1806240" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742413": { "compartment": "compartment_171062", "id": "reaction_10742413", "reactome": "R-SPO-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10742410", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "species_113527" ] }, "reaction_10742369": { "compartment": "compartment_172574", "id": "reaction_10742369", "reactome": "R-SPO-1675795", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806198", "species_29356" ], "products": [ "species_1806195", "species_29372" ], "modifiers": [ [ "species_10742366", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10753143": { "compartment": "compartment_70101", "id": "reaction_10753143", "reactome": "R-SPO-6809309", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753127", "species_10742436" ], "products": [ "species_10753141" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10753161": { "compartment": "compartment_70101", "id": "reaction_10753161", "reactome": "R-SPO-6809707", "name": "MTMR12 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753153", "species_10742360" ], "products": [ "species_10753159" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742493": { "compartment": "compartment_876", "id": "reaction_10742493", "reactome": "R-SPO-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10742490", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "Q9USQ6", "SPBC577.13" ] }, "reaction_10742343": { "compartment": "compartment_876", "id": "reaction_10742343", "reactome": "R-SPO-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806240" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10742340", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14" ] }, "reaction_10753173": { "compartment": "compartment_70101", "id": "reaction_10753173", "reactome": "R-SPO-6809777", "name": "PI3P is dephosphorylated to PI by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10753168", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742470": { "compartment": "compartment_20699", "id": "reaction_10742470", "reactome": "R-SPO-1676133", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806217" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10742459", "catalyst" ] ], "additional_components": [ "SPBC19F5.03" ] }, "reaction_10742427": { "compartment": "compartment_171062", "id": "reaction_10742427", "reactome": "R-SPO-1675974", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806180" ], "modifiers": [ [ "species_10742348", "catalyst" ] ], "additional_components": [ "SPAC343.19" ] }, "reaction_10732994": { "compartment": "compartment_7660", "id": "reaction_10732994", "reactome": "R-SPO-75079", "name": "Formation of AT-AC C complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732990" ], "products": [ "species_10732982", "species_10732992" ], "modifiers": [], "additional_components": [ "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "Q9UUI3", "SPAC22F8.10c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q10178", "SPAC27F1.09c", "O74825", "SPBC337.14", "O94620", "SPBC1289.11", "Q9UUC6", "SPBC19C2.14", "Q02061", "SPAC23G3.01", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "Q9P7R6", "SPBC211.05", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05", "Q9UUC6", "SPBC19C2.14", "Q10163", "SPAC26A3.08", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "Q9USZ3", "SPBC11G11.06c", "O14036", "SPAC2C4.03c", "O74966", "SPBC4B4.05", "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "P36594", "SPBC28F2.12", "Q9UUI3", "SPAC22F8.10c", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q10178", "SPAC27F1.09c", "O94620", "SPBC1289.11", "Q02061", "SPAC23G3.01", "Q9UUC6", "SPBC19C2.14", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "P48011", "SPBC19C2.03", "Q9P7R6", "SPBC211.05", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05" ] }, "reaction_10732996": { "compartment": "compartment_7660", "id": "reaction_10732996", "reactome": "R-SPO-75082", "name": "ATAC spliceosome mediated Lariat formation,5' splice site cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732992" ], "products": [ "species_10732992" ], "modifiers": [], "additional_components": [ "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "P36594", "SPBC28F2.12", "Q9UUI3", "SPAC22F8.10c", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q10178", "SPAC27F1.09c", "O94620", "SPBC1289.11", "Q02061", "SPAC23G3.01", "Q9UUC6", "SPBC19C2.14", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "P48011", "SPBC19C2.03", "Q9P7R6", "SPBC211.05", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05", "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "P36594", "SPBC28F2.12", "Q9UUI3", "SPAC22F8.10c", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q10178", "SPAC27F1.09c", "O94620", "SPBC1289.11", "Q02061", "SPAC23G3.01", "Q9UUC6", "SPBC19C2.14", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "P48011", "SPBC19C2.03", "Q9P7R6", "SPBC211.05", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05" ] }, "reaction_10729563": { "compartment": "compartment_70101", "id": "reaction_10729563", "reactome": "R-SPO-69191", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729559", "species_10729541" ], "products": [ "species_10729561" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "SPBC11B10.09", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10735839": { "compartment": "compartment_7660", "id": "reaction_10735839", "reactome": "R-SPO-188350", "name": "CAK-mediated phosphorylation of Cyclin E:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10729567" ], "products": [ "species_113582", "species_10729404" ], "modifiers": [ [ "species_10732457", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07" ] }, "reaction_10729580": { "compartment": "compartment_7660", "id": "reaction_10729580", "reactome": "R-SPO-69199", "name": "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729572", "species_113518" ], "products": [ "species_113550", "species_10729567" ], "modifiers": [ [ "species_10729577", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "SPAC24H6.05" ] }, "reaction_10734745": { "compartment": "compartment_13231", "id": "reaction_10734745", "reactome": "R-SPO-157906", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729561" ], "products": [ "species_10729567" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10747656": { "compartment": "compartment_7660", "id": "reaction_10747656", "reactome": "R-SPO-5685230", "name": "CHEK1 phosphorylates RAD51", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747651" ], "products": [ "species_113582", "species_10747654" ], "modifiers": [ [ "species_10729605", "catalyst" ] ], "additional_components": [ "SPAC644.14c", "SPAC644.14c", "O13945", "SPAC23H4.02", "O74536", "SPCC74.03c" ] }, "reaction_10747710": { "compartment": "compartment_7660", "id": "reaction_10747710", "reactome": "R-SPO-5687464", "name": "MRN and RBBP8 resect DNA DSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747703" ], "products": [ "species_10747707", "species_30555" ], "modifiers": [ [ "species_10747703", "catalyst" ] ], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10733424": { "compartment": "compartment_7660", "id": "reaction_10733424", "reactome": "R-SPO-75998", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733420" ], "products": [ "species_10733422" ], "modifiers": [], "additional_components": [ "SPAC30D11.10", "P36592", "SPAC30D11.10" ] }, "reaction_10747593": { "compartment": "compartment_7660", "id": "reaction_10747593", "reactome": "R-SPO-5684140", "name": "ATM phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747581" ], "products": [ "species_113582", "species_10747590" ], "modifiers": [ [ "species_10747581", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747723": { "compartment": "compartment_7660", "id": "reaction_10747723", "reactome": "R-SPO-5687664", "name": "FEN1 cleaves displaced ssDNA flaps during MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747716" ], "products": [ "species_10747720", "species_10729528", "species_68454" ], "modifiers": [ [ "species_10747716", "catalyst" ] ], "additional_components": [ "P39750", "SPAC3G6.06c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "SPAC3G6.06c", "P39750", "SPAC3G6.06c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747676": { "compartment": "compartment_7660", "id": "reaction_10747676", "reactome": "R-SPO-5686430", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747661", "species_10747668" ], "products": [ "species_10747674" ], "modifiers": [], "additional_components": [ "SPAPB1E7.06c", "SPCC4G3.05c", "Q9C103", "SPAPB1E7.06c", "P87231", "SPCC4G3.05c" ] }, "reaction_10747584": { "compartment": "compartment_7660", "id": "reaction_10747584", "reactome": "R-SPO-5684096", "name": "CDK2 phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747575" ], "products": [ "species_113582", "species_10728937", "species_10747581" ], "modifiers": [ [ "species_10747575", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "P36630", "SPAPB2B4.03", "Q09683", "SPAC13C5.07", "P10815", "SPBC582.03", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "P36630", "SPAPB2B4.03", "Q09683", "SPAC13C5.07", "P10815", "SPBC582.03", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10756974": { "compartment": "compartment_70101", "id": "reaction_10756974", "reactome": "R-SPO-9018877", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023708", "species_29356" ], "products": [ "species_9023712" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756059": { "compartment": "compartment_7660", "id": "reaction_10756059", "reactome": "R-SPO-8943007", "name": "SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756041", "species_10746403", "species_10733964", "species_10756047" ], "products": [ "species_10756049" ], "modifiers": [], "additional_components": [ "SPAC144.05", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9UTL9", "SPAC144.05", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10756057": { "compartment": "compartment_7660", "id": "reaction_10756057", "reactome": "R-SPO-8943003", "name": "SHPRH polyubiquitinates monoubiquitinated PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756049", "species_10756047" ], "products": [ "species_10756041", "species_10756054", "species_10746403", "species_10747373" ], "modifiers": [ [ "species_10756049", "catalyst" ] ], "additional_components": [ "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9UTL9", "SPAC144.05", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "SPAC144.05", "Q03392", "SPBC16D10.09", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9UTL9", "SPAC144.05", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10756390": { "compartment": "compartment_17947", "id": "reaction_10756390", "reactome": "R-SPO-8953946", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756378" ], "products": [ "species_10756387", "species_10741537" ], "modifiers": [ [ "species_10756378", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "O60065", "SPBC13G1.03c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O14136", "SPAC3C7.10", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH07", "SPAC1805.12c", "O60065", "SPBC13G1.03c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O14136", "SPAC3C7.10", "P0CH06", "SPAC11G7.04" ] }, "reaction_10756380": { "compartment": "compartment_17947", "id": "reaction_10756380", "reactome": "R-SPO-8953917", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756372", "species_10756376" ], "products": [ "species_10756378" ], "modifiers": [], "additional_components": [ "O60065", "SPBC13G1.03c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "O60065", "SPBC13G1.03c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O14136", "SPAC3C7.10", "P0CH06", "SPAC11G7.04" ] }, "reaction_10733705": { "compartment": "compartment_7660", "id": "reaction_10733705", "reactome": "R-SPO-109636", "name": "Recognition and Binding of Core Promoter Elements by TFIID", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109627", "species_10732699" ], "products": [ "species_10732998" ], "modifiers": [], "additional_components": [ "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c" ] }, "reaction_10733707": { "compartment": "compartment_7660", "id": "reaction_10733707", "reactome": "R-SPO-109637", "name": "Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732619", "species_10732998", "species_10732624" ], "products": [ "species_10733000" ], "modifiers": [], "additional_components": [ "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "SPAC16E8.16", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c" ] }, "reaction_10733709": { "compartment": "compartment_7660", "id": "reaction_10733709", "reactome": "R-SPO-109638", "name": "Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733000", "species_10730708" ], "products": [ "species_10733002" ], "modifiers": [], "additional_components": [ "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c" ] }, "reaction_10733006": { "compartment": "compartment_7660", "id": "reaction_10733006", "reactome": "R-SPO-75095", "name": "Binding of TFIIE to the growing preinitiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732711", "species_10733002" ], "products": [ "species_10733004" ], "modifiers": [], "additional_components": [ "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c" ] }, "reaction_10733711": { "compartment": "compartment_7660", "id": "reaction_10733711", "reactome": "R-SPO-109639", "name": "Formation of the closed pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733004", "species_10732494" ], "products": [ "species_10733340" ], "modifiers": [], "additional_components": [ "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750331": { "compartment": "compartment_5460", "id": "reaction_10750331", "reactome": "R-SPO-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10750328", "catalyst" ] ], "additional_components": [ "Q9P7Y7", "SPAPYUG7.05" ] }, "reaction_10729991": { "compartment": "compartment_70101", "id": "reaction_10729991", "reactome": "R-SPO-70606", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_31633" ], "products": [ "species_29370", "species_29472", "species_29372" ], "modifiers": [ [ "species_10729988", "catalyst" ] ], "additional_components": [ "Q09179", "SPAC23H4.06" ] }, "reaction_10730012": { "compartment": "compartment_5460", "id": "reaction_10730012", "reactome": "R-SPO-70654", "name": "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113585" ], "products": [ "species_31339", "species_113552" ], "modifiers": [ [ "species_10730009", "catalyst" ] ], "additional_components": [ "Q9P7L5", "SPBC21C3.08c" ] }, "reaction_10729993": { "compartment": "compartment_5460", "id": "reaction_10729993", "reactome": "R-SPO-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113587" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10729968", "catalyst" ] ], "additional_components": [ "O94320", "SPBC725.01" ] }, "reaction_10730022": { "compartment": "compartment_5460", "id": "reaction_10730022", "reactome": "R-SPO-70664", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10730019", "catalyst" ] ], "additional_components": [ "Q9P7Y7", "SPAPYUG7.05" ] }, "reaction_10740180": { "compartment": "compartment_5460", "id": "reaction_10740180", "reactome": "R-SPO-508040", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_113552", "species_113529", "species_113593" ], "products": [ "species_31339", "species_113548", "species_113563", "species_113581" ], "modifiers": [ [ "species_10740177", "catalyst" ] ], "additional_components": [ "Q9UT44", "SPAC821.11" ] }, "reaction_10740380": { "compartment": "compartment_70101", "id": "reaction_10740380", "reactome": "R-SPO-893616", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29398" ], "products": [ "species_893598", "species_29432" ], "modifiers": [ [ "species_10740371", "catalyst" ] ], "additional_components": [ "O14209", "SPAC6B12.04c" ] }, "reaction_10750338": { "compartment": "compartment_70101", "id": "reaction_10750338", "reactome": "R-SPO-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_35305" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10750335", "catalyst" ] ], "additional_components": [ "Q9P7Y7", "SPAPYUG7.05" ] }, "reaction_10734483": { "compartment": "compartment_17906", "id": "reaction_10734483", "reactome": "R-SPO-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734481" ], "products": [ "species_10734479" ], "modifiers": [], "additional_components": [ "SPCC191.07", "SPCC191.07" ] }, "reaction_10752635": { "compartment": "compartment_984", "id": "reaction_10752635", "reactome": "R-SPO-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737741" ], "products": [ "species_10752522" ], "modifiers": [], "additional_components": [ "SPAC57A10.09c", "SPAC57A10.09c" ] }, "reaction_10745096": { "compartment": "compartment_7660", "id": "reaction_10745096", "reactome": "R-SPO-5082384", "name": "HSP70:DNAJB1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744254", "species_10744224" ], "products": [ "species_10744256" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O59855", "SPCC1739.13", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06" ] }, "reaction_10744320": { "compartment": "compartment_7660", "id": "reaction_10744320", "reactome": "R-SPO-3371582", "name": "HSBP1 binds HSF1 trimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744252", "species_10744316" ], "products": [ "species_10744318" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14330", "SPBC16E9.15", "O14330", "SPBC16E9.15", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10757482": { "compartment": "compartment_70101", "id": "reaction_10757482", "reactome": "R-SPO-9635743", "name": "PTPN7 binds p-T,Y-MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757459", "species_10744304" ], "products": [ "species_10757461" ], "modifiers": [], "additional_components": [ "P27574", "SPAC26F1.10c", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01" ] }, "reaction_10746868": { "compartment": "compartment_70101", "id": "reaction_10746868", "reactome": "R-SPO-5674496", "name": "Activated MAPKs phosphorylate MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746838", "species_113592" ], "products": [ "species_29370", "species_10746865" ], "modifiers": [ [ "species_10746855", "catalyst" ] ], "additional_components": [ "P10506", "SPAC1D4.13", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10746885": { "compartment": "compartment_7660", "id": "reaction_10746885", "reactome": "R-SPO-5675373", "name": "Nuclear DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746859", "species_29356" ], "products": [ "species_10746870", "species_113550" ], "modifiers": [ [ "species_10746872", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPBC1685.01" ] }, "reaction_10757480": { "compartment": "compartment_70101", "id": "reaction_10757480", "reactome": "R-SPO-9635739", "name": "PTPN7 dephosphorylates p-T,Y-MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757461", "species_29356" ], "products": [ "species_10757477", "species_29372" ], "modifiers": [ [ "species_10757461", "catalyst" ] ], "additional_components": [ "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01", "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01", "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01" ] }, "reaction_10746906": { "compartment": "compartment_70101", "id": "reaction_10746906", "reactome": "R-SPO-5675376", "name": "Cytosolic DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10746855" ], "products": [ "species_10746891", "species_29372" ], "modifiers": [ [ "species_10746893", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPBC1685.01" ] }, "reaction_10745486": { "compartment": "compartment_7660", "id": "reaction_10745486", "reactome": "R-SPO-5228523", "name": "RANBP2 SUMOylates MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743716", "species_10743647" ], "products": [ "species_10743639", "species_10743724" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPCC285.17", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "O74503", "SPCC285.17", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10743731": { "compartment": "compartment_7660", "id": "reaction_10743731", "reactome": "R-SPO-3000434", "name": "PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743716", "species_10743647" ], "products": [ "species_10743639", "species_10743724" ], "modifiers": [ [ "species_10743726", "catalyst" ] ], "additional_components": [ "SPCC285.17", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "O74503", "SPCC285.17", "SPAC1687.05" ] }, "reaction_10751267": { "compartment": "compartment_876", "id": "reaction_10751267", "reactome": "R-SPO-6797630", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_417891", "species_109276" ], "products": [ "species_6797635", "species_109277" ], "modifiers": [ [ "species_10751264", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10757778": { "compartment": "compartment_70101", "id": "reaction_10757778", "reactome": "R-SPO-9668419", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738115", "species_113592", "species_29356" ], "products": [ "species_10738111", "species_29370", "species_29372" ], "modifiers": [ [ "species_10757769", "catalyst" ] ], "additional_components": [ "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c" ] }, "reaction_10743751": { "compartment": "compartment_13231", "id": "reaction_10743751", "reactome": "R-SPO-3000449", "name": "UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743738", "species_10743647" ], "products": [ "species_10743639", "species_10743748" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "P41391", "SPAC22E12.07", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P41391", "SPAC22E12.07", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10757349": { "compartment": "compartment_1598585", "id": "reaction_10757349", "reactome": "R-SPO-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737260", "species_29438" ], "products": [ "species_10745968", "species_29420" ], "modifiers": [ [ "species_10757346", "catalyst" ] ], "additional_components": [ "species_29420", "P28748", "SPBC1289.03c", "P28748", "SPBC1289.03c", "species_29438", "SPBC557.03c" ] }, "reaction_10757341": { "compartment": "compartment_13231", "id": "reaction_10757341", "reactome": "R-SPO-9624798", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737539", "species_10757337" ], "products": [ "species_10757339" ], "modifiers": [], "additional_components": [ "SPAC1B1.03c", "SPBC16G5.18", "Q09195", "SPBC16G5.18", "O13864", "SPAC1B1.03c" ] }, "reaction_10757773": { "compartment": "compartment_70101", "id": "reaction_10757773", "reactome": "R-SPO-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757769", "species_10740625" ], "products": [ "species_10757771" ], "modifiers": [], "additional_components": [ "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "SPAC2G11.06", "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "Q09803", "SPAC2G11.06", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c" ] }, "reaction_10743193": { "compartment": "compartment_70101", "id": "reaction_10743193", "reactome": "R-SPO-2467775", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743182" ], "products": [ "species_10743190" ], "modifiers": [ [ "species_10743182", "catalyst" ] ], "additional_components": [ "SPCC5E4.04", "P18296", "SPCC5E4.04", "SPCC5E4.04" ] }, "reaction_10757442": { "compartment": "compartment_70101", "id": "reaction_10757442", "reactome": "R-SPO-9634169", "name": "POM121 and NDC1 bind the Nup93 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757438", "species_10757311", "species_10733090", "species_10757436" ], "products": [ "species_10757440" ], "modifiers": [], "additional_components": [ "SPAP27G11.10c", "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "Q09904", "SPAC30D11.04c", "O36030", "SPAC4F10.18", "Q10331", "SPBC428.01c", "Q9UTK4", "SPAC1486.05", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "Q9UUE5", "SPBC17G9.04c", "O43044", "SPBC3B9.16c", "SPAC1786.03", "O94418", "SPCC1620.11", "O13838", "SPAC19E9.01c", "P78847", "SPCC290.03c", "Q9URX8", "SPAC890.06", "O94418", "SPCC1620.11", "Q09904", "SPAC30D11.04c", "Q10331", "SPBC428.01c", "P78847", "SPCC290.03c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q9UUE5", "SPBC17G9.04c", "Q9P7M8", "SPAP27G11.10c", "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "O13961", "SPAC1786.03", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "O43044", "SPBC3B9.16c" ] }, "reaction_10757353": { "compartment": "compartment_70101", "id": "reaction_10757353", "reactome": "R-SPO-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9624879", "species_10745968" ], "products": [ "species_10757351" ], "modifiers": [], "additional_components": [ "P28748", "SPBC1289.03c", "species_29438", "P28748", "SPBC1289.03c", "species_29438" ] }, "reaction_10743226": { "compartment": "compartment_70101", "id": "reaction_10743226", "reactome": "R-SPO-2467798", "name": "PTTG1 (Securin) sequesters ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743182", "species_10743222" ], "products": [ "species_10743224" ], "modifiers": [], "additional_components": [ "SPCC5E4.04", "SPBC14C8.01c", "P18296", "SPCC5E4.04", "P21135", "SPBC14C8.01c" ] }, "reaction_10757356": { "compartment": "compartment_70101", "id": "reaction_10757356", "reactome": "R-SPO-9624893", "name": "RAN stimulates fusion of nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757351", "species_29356" ], "products": [ "species_10737260", "species_29372", "species_9624890" ], "modifiers": [ [ "species_10743748", "catalyst" ] ], "additional_components": [ "P28748", "SPBC1289.03c", "species_29438", "species_29420", "P28748", "SPBC1289.03c", "O13351", "SPBC365.06", "P41391", "SPAC22E12.07" ] }, "reaction_10757775": { "compartment": "compartment_70101", "id": "reaction_10757775", "reactome": "R-SPO-9668405", "name": "SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757757", "species_10757767" ], "products": [ "species_10757769" ], "modifiers": [], "additional_components": [ "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c" ] }, "reaction_10757313": { "compartment": "compartment_70101", "id": "reaction_10757313", "reactome": "R-SPO-9618378", "name": "POM121 binds the Nup107-Nup160 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757309", "species_10733083" ], "products": [ "species_10757311" ], "modifiers": [], "additional_components": [ "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "O36030", "SPAC4F10.18", "Q10331", "SPBC428.01c", "Q9UTK4", "SPAC1486.05", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "Q9UUE5", "SPBC17G9.04c", "O43044", "SPBC3B9.16c", "SPAC30D11.04c", "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "Q09904", "SPAC30D11.04c", "O36030", "SPAC4F10.18", "Q10331", "SPBC428.01c", "Q9UTK4", "SPAC1486.05", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "Q9UUE5", "SPBC17G9.04c", "O43044", "SPBC3B9.16c" ] }, "reaction_10758064": { "compartment": "compartment_70101", "id": "reaction_10758064", "reactome": "R-SPO-9748957", "name": "GMPS dimer transforms 6TXMP to 6TGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29356", "species_9748959" ], "products": [ "species_70106", "species_9748970", "species_29404", "species_111294", "species_76577" ], "modifiers": [ [ "species_10758061", "catalyst" ] ], "additional_components": [ "Q9P772", "SPBC2F12.14c" ] }, "reaction_10758081": { "compartment": "compartment_70101", "id": "reaction_10758081", "reactome": "R-SPO-9750546", "name": "ABCC4 transports TPMP substrates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750587", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750548", "species_29372" ], "modifiers": [ [ "species_10741716", "catalyst" ] ], "additional_components": [ "species_9748992", "species_9748970", "pubchem.compound:3037883", "CHEBI:80613", "pubchem.compound:3037883", "CHEBI:2332", "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10758059": { "compartment": "compartment_70101", "id": "reaction_10758059", "reactome": "R-SPO-9748949", "name": "GUK1 phosphorylates 6TGMP to 6TGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748970", "species_113592" ], "products": [ "species_29370", "species_9748960" ], "modifiers": [ [ "species_10732507", "catalyst" ] ], "additional_components": [ "SPBC1198.05" ] }, "reaction_10758057": { "compartment": "compartment_70101", "id": "reaction_10758057", "reactome": "R-SPO-9748945", "name": "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748992", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_9748959" ], "modifiers": [ [ "species_10732525", "catalyst" ] ], "additional_components": [ "O14344", "SPBC2F12.14c" ] }, "reaction_10758087": { "compartment": "compartment_70101", "id": "reaction_10758087", "reactome": "R-SPO-9753278", "name": "ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10741710", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "CHEBI:132962", "CHEBI:32636", "CHEBI:32635", "Q10185", "SPAC3F10.11c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10758096": { "compartment": "compartment_70101", "id": "reaction_10758096", "reactome": "R-SPO-9753632", "name": "CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753680", "species_29356" ], "products": [ "species_9753653", "species_29424" ], "modifiers": [ [ "species_10741586", "catalyst" ] ], "additional_components": [ "Q9P6I2", "SPBC1198.08", "species_113527" ] }, "reaction_10758070": { "compartment": "compartment_70101", "id": "reaction_10758070", "reactome": "R-SPO-9748999", "name": "NME1:2 hexamer phosphorylates 6TGDP to 6TGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9748960" ], "products": [ "species_29370", "species_9748947" ], "modifiers": [ [ "species_10740061", "catalyst" ] ], "additional_components": [ "P49740", "SPAC806.07" ] }, "reaction_10758089": { "compartment": "compartment_70101", "id": "reaction_10758089", "reactome": "R-SPO-9753283", "name": "ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10741716", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "CHEBI:132962", "CHEBI:32636", "CHEBI:32635", "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10758068": { "compartment": "compartment_70101", "id": "reaction_10758068", "reactome": "R-SPO-9748969", "name": "NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9749033" ], "products": [ "species_29370", "species_9749032" ], "modifiers": [ [ "species_10740061", "catalyst" ] ], "additional_components": [ "P49740", "SPAC806.07" ] }, "reaction_10758084": { "compartment": "compartment_70101", "id": "reaction_10758084", "reactome": "R-SPO-9750656", "name": "ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750692", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750678", "species_29372" ], "modifiers": [ [ "species_10741710", "catalyst" ] ], "additional_components": [ "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "CHEBI:176960", "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "CHEBI:176960", "Q10185", "SPAC3F10.11c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10742965": { "compartment": "compartment_70101", "id": "reaction_10742965", "reactome": "R-SPO-2162078", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161185", "species_29360" ], "products": [ "species_70106", "species_73473", "species_2162081" ], "modifiers": [ [ "species_10730504", "catalyst" ] ], "additional_components": [ "species_442320", "P78870", "SPCC13B11.04c", "O74540", "SPCC13B11.04c" ] }, "reaction_10758066": { "compartment": "compartment_70101", "id": "reaction_10758066", "reactome": "R-SPO-9748963", "name": "GUK1 phosphorylates 6TdGMP to 6TdGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9749031", "species_113592" ], "products": [ "species_29370", "species_9749033" ], "modifiers": [ [ "species_10732507", "catalyst" ] ], "additional_components": [ "SPBC1198.05" ] }, "reaction_10758098": { "compartment": "compartment_876", "id": "reaction_10758098", "reactome": "R-SPO-9753634", "name": "GGT dimers hydrolyse APAP-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753685", "species_29356" ], "products": [ "species_9753680", "species_29404" ], "modifiers": [ [ "species_10745932", "catalyst" ] ], "additional_components": [ "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10758094": { "compartment": "compartment_70101", "id": "reaction_10758094", "reactome": "R-SPO-9753284", "name": "ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9753629", "species_29356" ], "products": [ "species_29370", "species_9753624", "species_29372" ], "modifiers": [ [ "species_10758091", "catalyst" ] ], "additional_components": [ "CHEBI:133438", "species_9753653", "CHEBI:133066", "CHEBI:133435", "Q92337", "SPAC9E9.12c", "Q10185", "SPAC3F10.11c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10735847": { "compartment": "compartment_5460", "id": "reaction_10735847", "reactome": "R-SPO-188467", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_188458" ], "products": [ "species_188451", "species_31649" ], "modifiers": [ [ "species_10735844", "catalyst" ] ], "additional_components": [ "SPCC1223.03c" ] }, "reaction_10738355": { "compartment": "compartment_70101", "id": "reaction_10738355", "reactome": "R-SPO-389788", "name": "Activation of PAKs by RAC1 and CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738349", "species_10738231" ], "products": [ "species_10738353", "species_10738351" ], "modifiers": [], "additional_components": [ "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c" ] }, "reaction_10741676": { "compartment": "compartment_70101", "id": "reaction_10741676", "reactome": "R-SPO-1358791", "name": "Phosphorylation of USP8 by P-AKT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741666" ], "products": [ "species_29370", "species_10741674" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "O60079", "SPCC1494.05c", "Q9USM5", "SPCC16A11.12c", "O60079", "SPCC1494.05c", "Q9USM5", "SPCC16A11.12c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10757404": { "compartment": "compartment_70101", "id": "reaction_10757404", "reactome": "R-SPO-9627369", "name": "SEPT4 binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757400", "species_10745678" ], "products": [ "species_10757402" ], "modifiers": [], "additional_components": [ "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11", "SPCC962.02c", "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "O14064", "SPCC962.02c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11" ] }, "reaction_10732312": { "compartment": "compartment_70101", "id": "reaction_10732312", "reactome": "R-SPO-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73578" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10732309", "catalyst" ] ], "additional_components": [ "O94413", "SPCC1620.06c", "P41831", "SPCC1620.06c", "P87171", "SPCC1620.06c" ] }, "reaction_10735815": { "compartment": "compartment_70101", "id": "reaction_10735815", "reactome": "R-SPO-177784", "name": "ribose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10730283", "catalyst" ] ], "additional_components": [ "SPAC144.12" ] }, "reaction_10730278": { "compartment": "compartment_70101", "id": "reaction_10730278", "reactome": "R-SPO-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10730275", "catalyst" ] ], "additional_components": [ "O14105", "SPAC31G5.05c", "species_113531" ] }, "reaction_10750445": { "compartment": "compartment_70101", "id": "reaction_10750445", "reactome": "R-SPO-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10729638", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10734989": { "compartment": "compartment_70101", "id": "reaction_10734989", "reactome": "R-SPO-163764", "name": "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29878", "species_29512" ], "products": [ "species_29578", "species_29882" ], "modifiers": [ [ "species_10730293", "catalyst" ] ], "additional_components": [ "O42700", "SPCC1020.06c" ] }, "reaction_10736696": { "compartment": "compartment_70101", "id": "reaction_10736696", "reactome": "R-SPO-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10730275", "catalyst" ] ], "additional_components": [ "O14105", "SPAC31G5.05c", "species_113531" ] }, "reaction_10730248": { "compartment": "compartment_70101", "id": "reaction_10730248", "reactome": "R-SPO-71296", "name": "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31467", "species_29356" ], "products": [ "species_29996" ], "modifiers": [ [ "species_10730245", "catalyst" ] ], "additional_components": [ "SPCC16C4.10" ] }, "reaction_10730258": { "compartment": "compartment_70101", "id": "reaction_10730258", "reactome": "R-SPO-71299", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_29996" ], "products": [ "species_70106", "species_29732", "species_29364", "species_113528" ], "modifiers": [ [ "species_10730255", "catalyst" ] ], "additional_components": [ "P78812", "SPBC660.16" ] }, "reaction_10729691": { "compartment": "compartment_70101", "id": "reaction_10729691", "reactome": "R-SPO-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_30537" ], "products": [ "species_70106", "species_29364", "species_31467" ], "modifiers": [ [ "species_10729688", "catalyst" ] ], "additional_components": [ "species_29366", "O00091", "SPAC3A12.18" ] }, "reaction_10756527": { "compartment": "compartment_70101", "id": "reaction_10756527", "reactome": "R-SPO-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10729638", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10756433": { "compartment": "compartment_70101", "id": "reaction_10756433", "reactome": "R-SPO-8955844", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8955853" ], "products": [ "species_29370", "species_73578" ], "modifiers": [ [ "species_10756430", "catalyst" ] ], "additional_components": [ "SPBC16G5.02c" ] }, "reaction_10734063": { "compartment": "compartment_70101", "id": "reaction_10734063", "reactome": "R-SPO-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10732305", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_29372", "catalyst" ] ], "additional_components": [ "O94413", "SPCC1620.06c", "P41831", "SPCC1620.06c", "P87171", "SPCC1620.06c" ] }, "reaction_10743558": { "compartment": "compartment_70101", "id": "reaction_10743558", "reactome": "R-SPO-2730872", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742830", "species_74016", "species_10737034" ], "products": [ "species_10743532" ], "modifiers": [], "additional_components": [ "species_442320", "Q9UU93", "SPCC830.06", "Q12705", "SPBP4H10.04", "CHEBI:29034", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q12705", "SPBP4H10.04", "CHEBI:29034" ] }, "reaction_10744811": { "compartment": "compartment_70101", "id": "reaction_10744811", "reactome": "R-SPO-4551465", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744805" ], "products": [ "species_10744809" ], "modifiers": [], "additional_components": [ "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q12705", "SPBP4H10.04", "CHEBI:29034", "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "Q12705", "SPBP4H10.04", "O14008", "SPAC29A4.05", "CHEBI:29034" ] }, "reaction_10743992": { "compartment": "compartment_20699", "id": "reaction_10743992", "reactome": "R-SPO-3247836", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743986" ], "products": [ "species_10743990" ], "modifiers": [], "additional_components": [ "Q9UTI5", "SPAC15E1.06", "O74552", "SPCC777.13", "O94291", "SPBC887.06c", "Q10243", "SPAC4G9.13c", "Q9UTI5", "SPAC15E1.06", "O74552", "SPCC777.13", "O94291", "SPBC887.06c", "Q10243", "SPAC4G9.13c" ] }, "reaction_10750278": { "compartment": "compartment_7660", "id": "reaction_10750278", "reactome": "R-SPO-6782211", "name": "DNA polymerases delta, epsilon or kappa bind the TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749283", "species_10749285", "species_10750264", "species_10729448" ], "products": [ "species_10750276" ], "modifiers": [], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "O74944", "SPCC553.07c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P36617", "SPCC970.01", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "P87324", "SPAC27E2.05", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P36617", "SPCC970.01", "P87123", "SPAC3A12.07", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94508", "SPBC646.02", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750246": { "compartment": "compartment_7660", "id": "reaction_10750246", "reactome": "R-SPO-6782131", "name": "ERCC2-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10750232" ], "products": [ "species_113582", "species_10750243", "species_113550" ], "modifiers": [ [ "species_10750232", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750267": { "compartment": "compartment_7660", "id": "reaction_10750267", "reactome": "R-SPO-6782204", "name": "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750260" ], "products": [ "species_10750264" ], "modifiers": [ [ "species_10750260", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P36617", "SPCC970.01", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P36617", "SPCC970.01", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P36617", "SPCC970.01", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750258": { "compartment": "compartment_7660", "id": "reaction_10750258", "reactome": "R-SPO-6782138", "name": "ERCC5 and RPA bind TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747765", "species_10750254", "species_10729504" ], "products": [ "species_10750256" ], "modifiers": [], "additional_components": [ "SPBC3E7.08c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750262": { "compartment": "compartment_7660", "id": "reaction_10750262", "reactome": "R-SPO-6782141", "name": "Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750256", "species_10733829" ], "products": [ "species_10750260" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P36617", "SPCC970.01", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10757829": { "compartment": "compartment_7660", "id": "reaction_10757829", "reactome": "R-SPO-9684118", "name": "ERCC3-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10750243" ], "products": [ "species_113582", "species_10750254", "species_113550" ], "modifiers": [ [ "species_10750243", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750281": { "compartment": "compartment_7660", "id": "reaction_10750281", "reactome": "R-SPO-6782224", "name": "3' incision by ERCC5 (XPG) in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750276" ], "products": [ "species_10750269", "species_10747765", "species_10747770", "species_10733829" ], "modifiers": [ [ "species_10750276", "catalyst" ] ], "additional_components": [ "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "P87324", "SPAC27E2.05", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P36617", "SPCC970.01", "P87123", "SPAC3A12.07", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94508", "SPBC646.02", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "SPBC3E7.08c", "SPBC649.03", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "P87324", "SPAC27E2.05", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P36617", "SPCC970.01", "P87123", "SPAC3A12.07", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94508", "SPBC646.02", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c" ] }, "reaction_10740162": { "compartment": "compartment_876", "id": "reaction_10740162", "reactome": "R-SPO-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10740159", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10739398": { "compartment": "compartment_876", "id": "reaction_10739398", "reactome": "R-SPO-444160", "name": "VMAT1/2 can mediate the transport of biogenic amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444154" ], "products": [ "species_444152" ], "modifiers": [ [ "species_10739395", "catalyst" ] ], "additional_components": [ "CHEBI:18295", "species_351601", "CHEBI:18357", "CHEBI:28918", "species_209914", "CHEBI:18295", "species_351601", "CHEBI:18357", "CHEBI:28918", "species_209914", "O74852", "SPCC18.02" ] }, "reaction_10739315": { "compartment": "compartment_876", "id": "reaction_10739315", "reactome": "R-SPO-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_446589", "species_351626" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10739312", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "Q9USK3", "SPCC4B3.13", "Q10085", "SPCC4B3.13", "Q9UT92", "SPCC4B3.13" ] }, "reaction_10740155": { "compartment": "compartment_876", "id": "reaction_10740155", "reactome": "R-SPO-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10756479": { "compartment": "compartment_70101", "id": "reaction_10756479", "reactome": "R-SPO-8959798", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29418" ], "products": [ "species_266099" ], "modifiers": [ [ "species_10756476", "catalyst" ] ], "additional_components": [ "SPAC23C11.14" ] }, "reaction_10740289": { "compartment": "compartment_20699", "id": "reaction_10740289", "reactome": "R-SPO-742345", "name": "SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742368" ], "products": [ "species_205683" ], "modifiers": [ [ "species_10740286", "catalyst" ] ], "additional_components": [ "SPAC22F8.04" ] }, "reaction_10739323": { "compartment": "compartment_876", "id": "reaction_10739323", "reactome": "R-SPO-435366", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_158417" ], "modifiers": [ [ "species_10739320", "catalyst" ] ], "additional_components": [ "SPAC23C11.14" ] }, "reaction_10740865": { "compartment": "compartment_876", "id": "reaction_10740865", "reactome": "R-SPO-939763", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_947594", "species_113592", "species_29356" ], "products": [ "species_29370", "species_947588", "species_29372" ], "modifiers": [ [ "species_10740862", "catalyst" ] ], "additional_components": [ "species_1500646", "species_1500581", "species_1500646", "species_1500581", "Q10309", "SPAC6C3.06c", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O94296", "SPBC887.12", "Q09891", "SPAC24B11.12c" ] }, "reaction_10740157": { "compartment": "compartment_876", "id": "reaction_10740157", "reactome": "R-SPO-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10747160": { "compartment": "compartment_70101", "id": "reaction_10747160", "reactome": "R-SPO-5678863", "name": "CFTR transports Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_352022", "species_29356" ], "products": [ "species_29370", "species_188972", "species_29372" ], "modifiers": [ [ "species_10738217", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10745661": { "compartment": "compartment_70101", "id": "reaction_10745661", "reactome": "R-SPO-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10745658", "catalyst" ] ], "additional_components": [ "SPBC25H2.08c" ] }, "reaction_10745601": { "compartment": "compartment_70101", "id": "reaction_10745601", "reactome": "R-SPO-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5252122" ], "products": [ "species_29370", "species_5252016", "species_29372" ], "modifiers": [ [ "species_10745598", "catalyst" ] ], "additional_components": [ "O74431", "SPCC1672.11c", "O14022", "SPAC29A4.19c" ] }, "reaction_10739257": { "compartment": "compartment_876", "id": "reaction_10739257", "reactome": "R-SPO-432049", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10739254", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10740300": { "compartment": "compartment_20699", "id": "reaction_10740300", "reactome": "R-SPO-742373", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742353" ], "products": [ "species_742361" ], "modifiers": [ [ "species_10740294", "catalyst" ] ], "additional_components": [ "SPBC1734.09" ] }, "reaction_10740787": { "compartment": "compartment_20699", "id": "reaction_10740787", "reactome": "R-SPO-936883", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_113592", "species_29356" ], "products": [ "species_29370", "species_167012", "species_29372" ], "modifiers": [ [ "species_10740784", "catalyst" ] ], "additional_components": [ "O59868", "SPBC31E1.02c", "species_29926" ] }, "reaction_10739115": { "compartment": "compartment_876", "id": "reaction_10739115", "reactome": "R-SPO-429101", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429130", "species_351626" ], "products": [ "species_70106", "species_426910" ], "modifiers": [ [ "species_10739112", "catalyst" ] ], "additional_components": [ "SPAC4F8.15" ] }, "reaction_10739331": { "compartment": "compartment_1462052", "id": "reaction_10739331", "reactome": "R-SPO-437085", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10739328", "catalyst" ] ], "additional_components": [ "SPAC17D4.03c" ] }, "reaction_10740662": { "compartment": "compartment_74700", "id": "reaction_10740662", "reactome": "R-SPO-917841", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113592", "species_29356" ], "products": [ "species_29370", "species_74722", "species_29372" ], "modifiers": [ [ "species_10732848", "catalyst" ] ], "additional_components": [ "P50515", "SPAC1B3.14", "O43046", "SPBC3B9.18c", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O59823", "SPCC965.03", "O14046", "SPAC2C4.13", "O13742", "SPAC16E8.07c", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q69Z14", "SPBC1685.16", "Q9HDW6", "SPAPB2B4.05" ] }, "reaction_10749527": { "compartment": "compartment_70101", "id": "reaction_10749527", "reactome": "R-SPO-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5692450" ], "products": [ "species_29370", "species_29372", "species_5692484" ], "modifiers": [ [ "species_10749524", "catalyst" ] ], "additional_components": [ "O74431", "SPCC1672.11c", "O14022", "SPAC29A4.19c" ] }, "reaction_10754737": { "compartment": "compartment_70101", "id": "reaction_10754737", "reactome": "R-SPO-8866553", "name": "misfolded CFTR is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754735" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9P7V2", "SPAC30.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10740153": { "compartment": "compartment_876", "id": "reaction_10740153", "reactome": "R-SPO-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10755496": { "compartment": "compartment_70101", "id": "reaction_10755496", "reactome": "R-SPO-8875902", "name": "SLC45A3 transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10755493", "catalyst" ] ], "additional_components": [ "SPAC2F3.08" ] }, "reaction_10745471": { "compartment": "compartment_70101", "id": "reaction_10745471", "reactome": "R-SPO-5223317", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5223341", "species_113592", "species_29356" ], "products": [ "species_29370", "species_29372", "species_5223344" ], "modifiers": [ [ "species_10745468", "catalyst" ] ], "additional_components": [ "P78966", "SPBC25B2.02c" ] }, "reaction_10745674": { "compartment": "compartment_70101", "id": "reaction_10745674", "reactome": "R-SPO-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10745671", "catalyst" ] ], "additional_components": [ "SPAPB17E12.11" ] }, "reaction_10738200": { "compartment": "compartment_70616", "id": "reaction_10738200", "reactome": "R-SPO-382560", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_189444", "species_113593" ], "products": [ "species_113548", "species_113581", "species_71185" ], "modifiers": [ [ "species_10738197", "catalyst" ] ], "additional_components": [ "Q02592", "SPCC737.09c", "O14286", "SPAC15A10.01", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10739371": { "compartment": "compartment_12045", "id": "reaction_10739371", "reactome": "R-SPO-442393", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_442320" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10739368", "catalyst" ] ], "additional_components": [ "SPAP8A3.03" ] }, "reaction_10743495": { "compartment": "compartment_70101", "id": "reaction_10743495", "reactome": "R-SPO-2684901", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10743492", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "O13621", "SPBC691.05c" ] }, "reaction_10739417": { "compartment": "compartment_876", "id": "reaction_10739417", "reactome": "R-SPO-445714", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10739414", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10740665": { "compartment": "compartment_876", "id": "reaction_10740665", "reactome": "R-SPO-917870", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310" ], "products": [ "species_9707308" ], "modifiers": [ [ "species_10736861", "catalyst" ] ], "additional_components": [ "species_189444", "CHEBI:36144", "species_189444", "CHEBI:36144", "SPAC14C4.07" ] }, "reaction_10741727": { "compartment": "compartment_70101", "id": "reaction_10741727", "reactome": "R-SPO-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_1454930" ], "products": [ "species_29370", "species_1454919", "species_29372" ], "modifiers": [ [ "species_10741724", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q10185", "SPAC3F10.11c", "Q9P7V2", "SPAC30.04c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10740150": { "compartment": "compartment_876", "id": "reaction_10740150", "reactome": "R-SPO-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10738220": { "compartment": "compartment_876", "id": "reaction_10738220", "reactome": "R-SPO-383190", "name": "HCO3- transport through ion channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_29356" ], "products": [ "species_29370", "species_425425", "species_29372" ], "modifiers": [ [ "species_10738217", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10745669": { "compartment": "compartment_70101", "id": "reaction_10745669", "reactome": "R-SPO-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10745666", "catalyst" ] ], "additional_components": [ "SPAPB17E12.11" ] }, "reaction_10743514": { "compartment": "compartment_70101", "id": "reaction_10743514", "reactome": "R-SPO-2730692", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2731008" ], "products": [ "species_352022", "species_74722" ], "modifiers": [ [ "species_10743511", "catalyst" ] ], "additional_components": [ "O94287", "SPBC887.02", "O60159", "SPBC19C7.11" ] }, "reaction_10739264": { "compartment": "compartment_876", "id": "reaction_10739264", "reactome": "R-SPO-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10739261", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10749518": { "compartment": "compartment_70101", "id": "reaction_10749518", "reactome": "R-SPO-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29418", "species_29356" ], "products": [ "species_29370", "species_29372", "species_1981162" ], "modifiers": [ [ "species_10749515", "catalyst" ] ], "additional_components": [ "SPACUNK4.07c" ] }, "reaction_10754739": { "compartment": "compartment_876", "id": "reaction_10754739", "reactome": "R-SPO-8866851", "name": "CFTR transits to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754733" ], "products": [ "species_10738217" ], "modifiers": [], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c", "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10739339": { "compartment": "compartment_876", "id": "reaction_10739339", "reactome": "R-SPO-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10739336", "catalyst" ] ], "additional_components": [ "SPBC23G7.16" ] }, "reaction_10749496": { "compartment": "compartment_70101", "id": "reaction_10749496", "reactome": "R-SPO-5691131", "name": "CANDI binds CUL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749492", "species_10735499" ], "products": [ "species_10749494" ], "modifiers": [], "additional_components": [ "SPAC1565.07c", "SPAC17G6.12", "Q9P3A8", "SPAC1565.07c", "O13790", "SPAC17G6.12" ] }, "reaction_10740297": { "compartment": "compartment_20699", "id": "reaction_10740297", "reactome": "R-SPO-742354", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756" ], "products": [ "species_914003" ], "modifiers": [ [ "species_10740294", "catalyst" ] ], "additional_components": [ "SPBC1734.09" ] }, "reaction_10740281": { "compartment": "compartment_20699", "id": "reaction_10740281", "reactome": "R-SPO-741450", "name": "SLC35A3 exchanges UDP-GlcNAc for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735698", "species_162756" ], "products": [ "species_109402", "species_914003" ], "modifiers": [ [ "species_10740278", "catalyst" ] ], "additional_components": [ "SPCC1795.03" ] }, "reaction_10734940": { "compartment": "compartment_70616", "id": "reaction_10734940", "reactome": "R-SPO-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113592", "species_113581" ], "modifiers": [ [ "species_10734937", "catalyst" ] ], "additional_components": [ "Q09188", "SPBC530.10c" ] }, "reaction_10741748": { "compartment": "compartment_876", "id": "reaction_10741748", "reactome": "R-SPO-1467457", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1131652", "species_113592", "species_29356" ], "products": [ "species_29370", "species_29372", "species_1467459" ], "modifiers": [ [ "species_10741745", "catalyst" ] ], "additional_components": [ "Q02592", "SPCC737.09c", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10740795": { "compartment": "compartment_20699", "id": "reaction_10740795", "reactome": "R-SPO-936895", "name": "ATP7B transports cytosolic Cu2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_209799" ], "products": [ "species_29370", "species_936901", "species_29372" ], "modifiers": [ [ "species_10740792", "catalyst" ] ], "additional_components": [ "SPBC29A3.01" ] }, "reaction_10740273": { "compartment": "compartment_20699", "id": "reaction_10740273", "reactome": "R-SPO-727759", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_727753" ], "modifiers": [ [ "species_10740270", "catalyst" ] ], "additional_components": [ "SPBC21B10.09" ] }, "reaction_10740164": { "compartment": "compartment_876", "id": "reaction_10740164", "reactome": "R-SPO-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10740159", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10747157": { "compartment": "compartment_984", "id": "reaction_10747157", "reactome": "R-SPO-5678706", "name": "ABCB4 transports PC from plasma membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_429802", "species_29356" ], "products": [ "species_29370", "species_382539", "species_29372" ], "modifiers": [ [ "species_10747154", "catalyst" ] ], "additional_components": [ "Q02592", "SPCC737.09c", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10755815": { "compartment": "compartment_70101", "id": "reaction_10755815", "reactome": "R-SPO-8932851", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8932838" ], "products": [ "species_8932842" ], "modifiers": [ [ "species_10755812", "catalyst" ] ], "additional_components": [ "CHEBI:32513", "species_1131871", "species_29468", "CHEBI:32513", "species_1131871", "species_29468", "SPAC17C9.10" ] }, "reaction_10757945": { "compartment": "compartment_70101", "id": "reaction_10757945", "reactome": "R-SPO-9696271", "name": "RND1 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738543", "species_10757941" ], "products": [ "species_10757943" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9UTL2", "SPAC144.14", "Q9USZ0", "SPBC1306.02", "Q9USR1", "SPBC577.08c", "Q9USI5", "SPCC645.14c", "P08647", "SPAC17H9.09c", "O43023", "SPBC354.09c", "Q9UTL2", "SPAC144.14", "Q9HE04", "SPAC20H4.11c", "Q9USZ0", "SPBC1306.02", "Q9USR1", "SPBC577.08c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9USI5", "SPCC645.14c", "P08647", "SPAC17H9.09c", "O43023", "SPBC354.09c" ] }, "reaction_10757947": { "compartment": "compartment_70101", "id": "reaction_10757947", "reactome": "R-SPO-9696274", "name": "RND1 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10738541" ], "products": [ "species_10738543" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10733685": { "compartment": "compartment_7660", "id": "reaction_10733685", "reactome": "R-SPO-83788", "name": "Binding of TFIIIC to Type 2 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733480", "species_83747" ], "products": [ "species_10733683" ], "modifiers": [], "additional_components": [ "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733689": { "compartment": "compartment_7660", "id": "reaction_10733689", "reactome": "R-SPO-83790", "name": "Binding of TFIIIB to TFIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733683", "species_10733448" ], "products": [ "species_10733687" ], "modifiers": [], "additional_components": [ "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9UST7", "SPBC336.07", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733681": { "compartment": "compartment_7660", "id": "reaction_10733681", "reactome": "R-SPO-83723", "name": "Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733484", "species_10733448" ], "products": [ "species_10733486" ], "modifiers": [], "additional_components": [ "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "Q9UST7", "SPBC336.07", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733547": { "compartment": "compartment_7660", "id": "reaction_10733547", "reactome": "R-SPO-76056", "name": "Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733543", "species_10733486" ], "products": [ "species_10733545" ], "modifiers": [], "additional_components": [ "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "O13877", "SPAC1B3.12c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74857", "SPCC18.07", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "Q9UST7", "SPBC336.07", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O13650", "SPBC8D2.07c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "Q9P6R0", "SPBC13E7.10c", "O13877", "SPAC1B3.12c", "O74458", "SPCC16C4.14c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "O94481", "SPCC1919.14c", "Q92399", "SPBC14C8.12", "Q9UST7", "SPBC336.07", "O74857", "SPCC18.07", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733693": { "compartment": "compartment_7660", "id": "reaction_10733693", "reactome": "R-SPO-83805", "name": "Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733543", "species_10733687" ], "products": [ "species_10733691" ], "modifiers": [], "additional_components": [ "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "O13877", "SPAC1B3.12c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74857", "SPCC18.07", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9UST7", "SPBC336.07", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O13650", "SPBC8D2.07c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "Q9P6R0", "SPBC13E7.10c", "O13877", "SPAC1B3.12c", "O74458", "SPCC16C4.14c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "O94481", "SPCC1919.14c", "Q92399", "SPBC14C8.12", "Q9UST7", "SPBC336.07", "O74857", "SPCC18.07", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10736346": { "compartment": "compartment_876", "id": "reaction_10736346", "reactome": "R-SPO-196017", "name": "Dynamin is recruited to the gap junction plaque", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736046", "species_10736019" ], "products": [ "species_10736048" ], "modifiers": [], "additional_components": [ "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "O60054", "SPBC56F2.03", "P10989", "SPBC32H8.12c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q09718", "SPAC31A2.09c", "O60054", "SPBC56F2.03", "Q9URZ5", "SPAC767.01c", "P10989", "SPBC32H8.12c" ] }, "reaction_10739285": { "compartment": "compartment_17906", "id": "reaction_10739285", "reactome": "R-SPO-434382", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_200993" ], "modifiers": [ [ "species_10739282", "catalyst" ] ], "additional_components": [ "Q9P7D7", "SPBP4H10.11c", "O60135", "SPBC18H10.02" ] }, "reaction_10737145": { "compartment": "compartment_876", "id": "reaction_10737145", "reactome": "R-SPO-202692", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10734488" ], "products": [ "species_10737143" ], "modifiers": [], "additional_components": [ "SPAC1F7.04", "Q09914", "SPAC1F7.04", "species_179838" ] }, "reaction_10742675": { "compartment": "compartment_12045", "id": "reaction_10742675", "reactome": "R-SPO-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10742672", "catalyst" ] ], "additional_components": [ "species_74016", "P40977", "SPAC22F8.11" ] }, "reaction_10742665": { "compartment": "compartment_70101", "id": "reaction_10742665", "reactome": "R-SPO-1855205", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_114520", "species_29372" ], "modifiers": [ [ "species_10742662", "catalyst" ] ], "additional_components": [ "O94526", "SPBC609.02", "species_29926" ] }, "reaction_10742633": { "compartment": "compartment_70101", "id": "reaction_10742633", "reactome": "R-SPO-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10742630", "catalyst" ] ], "additional_components": [ "species_74016", "P40977", "SPAC22F8.11" ] }, "reaction_10742706": { "compartment": "compartment_876", "id": "reaction_10742706", "reactome": "R-SPO-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10742703", "catalyst" ] ], "additional_components": [ "species_74016", "P40977", "SPAC22F8.11" ] }, "reaction_10742681": { "compartment": "compartment_70101", "id": "reaction_10742681", "reactome": "R-SPO-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_994123", "species_29372" ], "modifiers": [ [ "species_10742605", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "Q9USQ6", "SPBC577.13" ] }, "reaction_10756065": { "compartment": "compartment_876", "id": "reaction_10756065", "reactome": "R-SPO-8943279", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247892", "species_109276" ], "products": [ "species_210382", "species_1247934" ], "modifiers": [ [ "species_10745932", "catalyst" ] ], "additional_components": [ "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10741599": { "compartment": "compartment_70101", "id": "reaction_10741599", "reactome": "R-SPO-1247935", "name": "OPLAH hydrolyses OPRO to L-Glu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1247942", "species_29356" ], "products": [ "species_29370", "species_29404", "species_29372" ], "modifiers": [ [ "species_10741596", "catalyst" ] ], "additional_components": [ "Q10094", "SPAC11D3.15" ] }, "reaction_10741589": { "compartment": "compartment_70101", "id": "reaction_10741589", "reactome": "R-SPO-1247910", "name": "CNDP2:2Mn2+ dimer hydrolyses CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247904", "species_29356" ], "products": [ "species_29424", "species_111707" ], "modifiers": [ [ "species_10741586", "catalyst" ] ], "additional_components": [ "Q9P6I2", "SPBC1198.08", "species_113527" ] }, "reaction_10735542": { "compartment": "compartment_70101", "id": "reaction_10735542", "reactome": "R-SPO-174367", "name": "GCL ligates L-Glu to L-Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111707", "species_29404" ], "products": [ "species_29370", "species_174393", "species_29372" ], "modifiers": [ [ "species_10735539", "catalyst" ] ], "additional_components": [ "O94246", "SPCC737.06c", "Q09768", "SPAC22F3.10c" ] }, "reaction_10735581": { "compartment": "compartment_70101", "id": "reaction_10735581", "reactome": "R-SPO-174394", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_174393", "species_113592" ], "products": [ "species_29370", "species_29450", "species_29372" ], "modifiers": [ [ "species_10735578", "catalyst" ], [ "species_29450", "inhibitor" ] ], "additional_components": [ "P35669", "SPAC3F10.04", "species_29926" ] }, "reaction_10750414": { "compartment": "compartment_70101", "id": "reaction_10750414", "reactome": "R-SPO-6785928", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450" ], "products": [ "species_1247904", "species_1247942" ], "modifiers": [ [ "species_10750411", "catalyst" ] ], "additional_components": [ "P87305", "SPBC31F10.03" ] }, "reaction_10757128": { "compartment": "compartment_17947", "id": "reaction_10757128", "reactome": "R-SPO-9033527", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757089", "species_10756376" ], "products": [ "species_10757091" ], "modifiers": [], "additional_components": [ "O60065", "SPBC13G1.03c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10" ] }, "reaction_10757083": { "compartment": "compartment_17947", "id": "reaction_10757083", "reactome": "R-SPO-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757067" ], "products": [ "species_10757081", "species_10756372" ], "modifiers": [], "additional_components": [ "O60065", "SPBC13G1.03c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "O94325", "SPBC725.07", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14077", "SPACUNK4.12c", "Q9Y7N4", "SPCC1450.07c", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O14136", "SPAC3C7.10", "O13717", "SPAC14C4.10c", "O14077", "SPACUNK4.12c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "Q9Y7N4", "SPCC1450.07c", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O13717", "SPAC14C4.10c", "O60065", "SPBC13G1.03c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10" ] }, "reaction_10757096": { "compartment": "compartment_17947", "id": "reaction_10757096", "reactome": "R-SPO-9033485", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757091" ], "products": [ "species_10741537", "species_10757093" ], "modifiers": [ [ "species_10757091", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P78798", "SPAC17D4.01", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10" ] }, "reaction_10757085": { "compartment": "compartment_17947", "id": "reaction_10757085", "reactome": "R-SPO-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757063", "species_10757065" ], "products": [ "species_10757067" ], "modifiers": [], "additional_components": [ "O14077", "SPACUNK4.12c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "Q9Y7N4", "SPCC1450.07c", "O94325", "SPBC725.07", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O13717", "SPAC14C4.10c", "O60065", "SPBC13G1.03c", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10", "O60065", "SPBC13G1.03c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "O94325", "SPBC725.07", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14077", "SPACUNK4.12c", "Q9Y7N4", "SPCC1450.07c", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O14136", "SPAC3C7.10", "O13717", "SPAC14C4.10c" ] }, "reaction_10736821": { "compartment": "compartment_70101", "id": "reaction_10736821", "reactome": "R-SPO-200423", "name": "pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736809", "species_113592" ], "products": [ "species_29370", "species_10736816" ], "modifiers": [ [ "species_10736818", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527", "P78820", "SPAC56E4.04c", "species_113527", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10755610": { "compartment": "compartment_70101", "id": "reaction_10755610", "reactome": "R-SPO-8876889", "name": "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10736809", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527" ] }, "reaction_10733326": { "compartment": "compartment_70101", "id": "reaction_10733326", "reactome": "R-SPO-75851", "name": "Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10733323", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527" ] }, "reaction_10736829": { "compartment": "compartment_17927", "id": "reaction_10736829", "reactome": "R-SPO-200424", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_201023", "species_201034" ], "products": [ "species_549207", "species_201050" ], "modifiers": [ [ "species_10736826", "catalyst" ] ], "additional_components": [ "SPBC29A3.11c" ] }, "reaction_10757932": { "compartment": "compartment_70101", "id": "reaction_10757932", "reactome": "R-SPO-9696267", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757928" ], "products": [ "species_10757930" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10729657": { "compartment": "compartment_70101", "id": "reaction_10729657", "reactome": "R-SPO-70286", "name": "UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29494", "species_29548" ], "products": [ "species_29410", "species_111294" ], "modifiers": [ [ "species_10729654", "catalyst" ] ], "additional_components": [ "P78811", "SPCC1322.04" ] }, "reaction_10729379": { "compartment": "compartment_7660", "id": "reaction_10729379", "reactome": "R-SPO-68954", "name": "Mcm2-7 is phosphorylated by DDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728861", "species_29358" ], "products": [ "species_113582", "species_10729376" ], "modifiers": [ [ "species_10728818", "catalyst" ] ], "additional_components": [ "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "species_29372", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "P50582", "SPBC776.12c", "O59836", "SPCC550.13" ] }, "reaction_10728884": { "compartment": "compartment_7660", "id": "reaction_10728884", "reactome": "R-SPO-68916", "name": "DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728877", "species_10728792" ], "products": [ "species_10728879" ], "modifiers": [], "additional_components": [ "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "Q92373", "SPCC1753.01c", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "Q92374", "SPCC23B6.05c", "O74796", "SPBC2A9.12", "Q92372", "SPBC660.13c", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728903": { "compartment": "compartment_7660", "id": "reaction_10728903", "reactome": "R-SPO-68940", "name": "Cdt1 is displaced from the pre-replicative complex.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728899" ], "products": [ "species_10728893", "species_10728873" ], "modifiers": [], "additional_components": [ "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "SPBC428.18", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728886": { "compartment": "compartment_7660", "id": "reaction_10728886", "reactome": "R-SPO-68917", "name": "Cdc45 associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728797", "species_10728875" ], "products": [ "species_10728877" ], "modifiers": [], "additional_components": [ "SPAC17D4.02", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10729381": { "compartment": "compartment_7660", "id": "reaction_10729381", "reactome": "R-SPO-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68419", "species_10728764" ], "products": [ "species_10728766" ], "modifiers": [ [ "species_10728879", "catalyst" ] ], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "Q92373", "SPCC1753.01c", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "Q92374", "SPCC23B6.05c", "O74796", "SPBC2A9.12", "Q92372", "SPBC660.13c", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728888": { "compartment": "compartment_7660", "id": "reaction_10728888", "reactome": "R-SPO-68918", "name": "CDK and DDK associate with the Mcm10:pre-replicative complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728806", "species_10728818", "species_10728873" ], "products": [ "species_10728875" ], "modifiers": [], "additional_components": [ "P04551", "SPBC11B10.09", "P50582", "SPBC776.12c", "O59836", "SPCC550.13", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728901": { "compartment": "compartment_7660", "id": "reaction_10728901", "reactome": "R-SPO-68919", "name": "Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728823", "species_10728897" ], "products": [ "species_10728899" ], "modifiers": [], "additional_components": [ "SPBC1347.10", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728881": { "compartment": "compartment_7660", "id": "reaction_10728881", "reactome": "R-SPO-68914", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728766", "species_10728742" ], "products": [ "species_10728768" ], "modifiers": [ [ "species_10728879", "catalyst" ] ], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "Q92373", "SPCC1753.01c", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "Q92374", "SPCC23B6.05c", "O74796", "SPBC2A9.12", "Q92372", "SPBC660.13c", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10745090": { "compartment": "compartment_7660", "id": "reaction_10745090", "reactome": "R-SPO-5082356", "name": "HSF1-mediated gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744254" ], "products": [ "species_10745068" ], "modifiers": [ [ "species_10745088", "catalyst" ], [ "species_10745078", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14330", "SPBC16E9.15", "P41887", "SPAC926.04c", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10745122": { "compartment": "compartment_7660", "id": "reaction_10745122", "reactome": "R-SPO-5082405", "name": "Phosphorylation of HSF1 at Ser326 induces transactivation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10744252" ], "products": [ "species_113582", "species_10745088" ], "modifiers": [ [ "species_10745119", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q9Y7K2", "SPBC216.07c", "P87141", "SPAC57A7.11", "O74184", "SPBC21B10.05c" ] }, "reaction_10742668": { "compartment": "compartment_7660", "id": "reaction_10742668", "reactome": "R-SPO-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742651": { "compartment": "compartment_70101", "id": "reaction_10742651", "reactome": "R-SPO-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10742646", "catalyst" ] ], "additional_components": [ "SPCC1672.06c" ] }, "reaction_10742712": { "compartment": "compartment_7660", "id": "reaction_10742712", "reactome": "R-SPO-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023940", "species_29358" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742814": { "compartment": "compartment_70101", "id": "reaction_10742814", "reactome": "R-SPO-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_2023974", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "CHEBI:62922", "species_1629740", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742641": { "compartment": "compartment_7660", "id": "reaction_10742641", "reactome": "R-SPO-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742603": { "compartment": "compartment_70101", "id": "reaction_10742603", "reactome": "R-SPO-1855166", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023943", "species_29356" ], "products": [ "species_29372", "species_994141" ], "modifiers": [ [ "species_10742591", "catalyst" ] ], "additional_components": [ "species_1629736", "species_1629755", "CHEBI:62927", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742657": { "compartment": "compartment_70101", "id": "reaction_10742657", "reactome": "R-SPO-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742715": { "compartment": "compartment_70101", "id": "reaction_10742715", "reactome": "R-SPO-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629765" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742580": { "compartment": "compartment_70101", "id": "reaction_10742580", "reactome": "R-SPO-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742654": { "compartment": "compartment_70101", "id": "reaction_10742654", "reactome": "R-SPO-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742616": { "compartment": "compartment_7660", "id": "reaction_10742616", "reactome": "R-SPO-1855176", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023929" ], "modifiers": [ [ "species_10742613", "catalyst" ] ], "additional_components": [ "SPCC4B3.10c" ] }, "reaction_10742812": { "compartment": "compartment_70101", "id": "reaction_10742812", "reactome": "R-SPO-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023974", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "CHEBI:62922", "species_1629740", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742709": { "compartment": "compartment_70101", "id": "reaction_10742709", "reactome": "R-SPO-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742718": { "compartment": "compartment_7660", "id": "reaction_10742718", "reactome": "R-SPO-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023922", "species_29358" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742678": { "compartment": "compartment_70101", "id": "reaction_10742678", "reactome": "R-SPO-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10742646", "catalyst" ] ], "additional_components": [ "SPCC1672.06c" ] }, "reaction_10742567": { "compartment": "compartment_7660", "id": "reaction_10742567", "reactome": "R-SPO-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742600": { "compartment": "compartment_70101", "id": "reaction_10742600", "reactome": "R-SPO-1855165", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_1629765", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742660": { "compartment": "compartment_70101", "id": "reaction_10742660", "reactome": "R-SPO-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742638": { "compartment": "compartment_70101", "id": "reaction_10742638", "reactome": "R-SPO-1855179", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629770" ], "modifiers": [ [ "species_10742635", "catalyst" ] ], "additional_components": [ "SPCC4B3.10c" ] }, "reaction_10742608": { "compartment": "compartment_70101", "id": "reaction_10742608", "reactome": "R-SPO-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114520", "species_29356" ], "products": [ "species_1629739", "species_29372" ], "modifiers": [ [ "species_10742605", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "Q9USQ6", "SPBC577.13" ] }, "reaction_10741541": { "compartment": "compartment_70101", "id": "reaction_10741541", "reactome": "R-SPO-1236970", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236719" ], "products": [ "species_983036", "species_8942986" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10733749": { "compartment": "compartment_70101", "id": "reaction_10733749", "reactome": "R-SPO-109702", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733734", "species_113592" ], "products": [ "species_29370", "species_10733746" ], "modifiers": [ [ "species_10733718", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10732851": { "compartment": "compartment_17940", "id": "reaction_10732851", "reactome": "R-SPO-74723", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_74722" ], "modifiers": [ [ "species_10732848", "catalyst" ] ], "additional_components": [ "P50515", "SPAC1B3.14", "O43046", "SPBC3B9.18c", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O59823", "SPCC965.03", "O14046", "SPAC2C4.13", "O13742", "SPAC16E8.07c", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q69Z14", "SPBC1685.16", "Q9HDW6", "SPAPB2B4.05" ] }, "reaction_10733720": { "compartment": "compartment_876", "id": "reaction_10733720", "reactome": "R-SPO-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733716", "species_179838" ], "products": [ "species_10733718" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10738628": { "compartment": "compartment_876", "id": "reaction_10738628", "reactome": "R-SPO-418574", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738468" ], "products": [ "species_10738625" ], "modifiers": [ [ "species_10738468", "catalyst" ] ], "additional_components": [ "species_29438", "Q04665", "SPAC23H3.13c", "species_111349", "Q04665", "SPAC23H3.13c", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10738681": { "compartment": "compartment_70101", "id": "reaction_10738681", "reactome": "R-SPO-419166", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738582", "species_29438" ], "products": [ "species_10738584", "species_29420" ], "modifiers": [ [ "species_10738678", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_111349", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q09763", "SPAC24H6.09", "O59679", "SPBC29A3.17", "Q9HGL2", "SPBC800.10c", "Q9USU1", "SPBC336.03", "P26674", "SPCC1442.01" ] }, "reaction_10738831": { "compartment": "compartment_70101", "id": "reaction_10738831", "reactome": "R-SPO-425861", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738827", "species_114519" ], "products": [ "species_10738829" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10734572": { "compartment": "compartment_876", "id": "reaction_10734572", "reactome": "R-SPO-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734567" ], "products": [ "species_10734569" ], "modifiers": [ [ "species_10734143", "catalyst" ] ], "additional_components": [ "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c", "species_179856", "species_114520", "species_1500596", "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c", "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c" ] }, "reaction_10738483": { "compartment": "compartment_876", "id": "reaction_10738483", "reactome": "R-SPO-400015", "name": "Diacylgycerol activates Protein kinase C, alpha type", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734508", "species_114519" ], "products": [ "species_10738481" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10757183": { "compartment": "compartment_70101", "id": "reaction_10757183", "reactome": "R-SPO-9603279", "name": "PIP3 recruits PDK1 and AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10737088", "species_10738396" ], "products": [ "species_10757181" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q12701", "SPCC576.15c" ] }, "reaction_10738633": { "compartment": "compartment_876", "id": "reaction_10738633", "reactome": "R-SPO-418582", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734141" ], "products": [ "species_10738630" ], "modifiers": [ [ "species_10734141", "catalyst" ] ], "additional_components": [ "species_29438", "Q04665", "SPAC23H3.13c", "species_111349", "Q04665", "SPAC23H3.13c", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10756978": { "compartment": "compartment_70101", "id": "reaction_10756978", "reactome": "R-SPO-9020253", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024781", "species_29356" ], "products": [ "species_9024809" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:138649", "CHEBI:138648", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756976": { "compartment": "compartment_70101", "id": "reaction_10756976", "reactome": "R-SPO-9020252", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024602", "species_29356" ], "products": [ "species_9024574" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:138179", "CHEBI:138614", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756982": { "compartment": "compartment_70101", "id": "reaction_10756982", "reactome": "R-SPO-9020258", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024768" ], "products": [ "species_9024759" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:81565", "CHEBI:81564", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756984": { "compartment": "compartment_70101", "id": "reaction_10756984", "reactome": "R-SPO-9020270", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024577" ], "products": [ "species_9024570" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:138616", "CHEBI:138615", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10736344": { "compartment": "compartment_70101", "id": "reaction_10736344", "reactome": "R-SPO-195664", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_195691" ], "products": [ "species_29366", "species_195655", "species_29356" ], "modifiers": [ [ "species_10736341", "catalyst" ] ], "additional_components": [ "O13666", "SPBC27B12.03c", "O94457", "SPAC1687.16c" ] }, "reaction_10737982": { "compartment": "compartment_70101", "id": "reaction_10737982", "reactome": "R-SPO-372449", "name": "phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] => phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_372364", "species_76190" ], "products": [ "species_29654", "species_29492" ], "modifiers": [ [ "species_10733305", "catalyst" ] ], "additional_components": [ "SPAC19G12.05" ] }, "reaction_10729759": { "compartment": "compartment_70101", "id": "reaction_10729759", "reactome": "R-SPO-70454", "name": "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75970" ], "products": [ "species_29578" ], "modifiers": [ [ "species_10729756", "catalyst" ] ], "additional_components": [ "P07669", "SPCC24B10.21" ] }, "reaction_10730569": { "compartment": "compartment_5460", "id": "reaction_10730569", "reactome": "R-SPO-71783", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113587", "species_113529" ], "products": [ "species_113526", "species_113544" ], "modifiers": [ [ "species_10730123", "catalyst" ] ], "additional_components": [ "Q9Y7R8", "SPCC306.08c" ] }, "reaction_10729720": { "compartment": "compartment_70101", "id": "reaction_10729720", "reactome": "R-SPO-70420", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_70113" ], "products": [ "species_70106", "species_29370", "species_30537" ], "modifiers": [ [ "species_10729717", "catalyst" ] ], "additional_components": [ "P50521", "SPAC4F8.07c", "Q09756", "SPAC24H6.04" ] }, "reaction_10751283": { "compartment": "compartment_70101", "id": "reaction_10751283", "reactome": "R-SPO-6798335", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800" ], "products": [ "species_6798337" ], "modifiers": [ [ "species_10751280", "catalyst" ] ], "additional_components": [ "P36623", "SPAC26F1.06" ] }, "reaction_10729809": { "compartment": "compartment_70101", "id": "reaction_10729809", "reactome": "R-SPO-70479", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10729806", "catalyst" ], [ "species_76577", "inhibitor" ] ], "additional_components": [ "species_29926", "P09202", "SPBC1198.14c" ] }, "reaction_10729793": { "compartment": "compartment_70101", "id": "reaction_10729793", "reactome": "R-SPO-70475", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10729788", "catalyst" ] ], "additional_components": [ "P78917", "SPBC1604.05" ] }, "reaction_10730470": { "compartment": "compartment_70101", "id": "reaction_10730470", "reactome": "R-SPO-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10730467", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_30389", "inhibitor" ], [ "species_29358", "inhibitor" ] ], "additional_components": [ "Q10208", "SPAC4H3.10c", "species_74126", "species_29926" ] }, "reaction_10735464": { "compartment": "compartment_13231", "id": "reaction_10735464", "reactome": "R-SPO-170825", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735462" ], "products": [ "species_10729703" ], "modifiers": [], "additional_components": [ "P50521", "SPAC4F8.07c", "Q09756", "SPAC24H6.04", "P50521", "SPAC4F8.07c", "Q09756", "SPAC24H6.04" ] }, "reaction_10756422": { "compartment": "compartment_70101", "id": "reaction_10756422", "reactome": "R-SPO-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800", "species_30537" ], "products": [ "species_70106", "species_29728", "species_8955759" ], "modifiers": [ [ "species_10729642", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10730609": { "compartment": "compartment_70101", "id": "reaction_10730609", "reactome": "R-SPO-71850", "name": "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_29800" ], "products": [ "species_113592", "species_29728" ], "modifiers": [ [ "species_10729826", "catalyst" ] ], "additional_components": [ "O60101", "SPBC14F5.04c", "species_29926" ] }, "reaction_10729856": { "compartment": "compartment_70101", "id": "reaction_10729856", "reactome": "R-SPO-70494", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29492", "species_29356" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10729853", "catalyst" ] ], "additional_components": [ "P40370", "SPBC1815.01", "Q8NKC2", "SPBPB21E7.01c", "species_29926" ] }, "reaction_10730452": { "compartment": "compartment_70101", "id": "reaction_10730452", "reactome": "R-SPO-71654", "name": "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29728" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10730341", "catalyst" ] ], "additional_components": [ "P36623", "SPAC26F1.06" ] }, "reaction_10729813": { "compartment": "compartment_70101", "id": "reaction_10729813", "reactome": "R-SPO-70482", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_29800" ], "products": [ "species_29578", "species_29360", "species_29372" ], "modifiers": [ [ "species_10729746", "catalyst" ] ], "additional_components": [ "O43026", "SPBC354.12", "P78958", "SPBC32F12.11" ] }, "reaction_10729781": { "compartment": "compartment_70101", "id": "reaction_10729781", "reactome": "R-SPO-70467", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30014" ], "modifiers": [ [ "species_10729778", "catalyst" ], [ "species_29370", "catalyst" ], [ "species_76577", "catalyst" ], [ "species_30533", "catalyst" ], [ "species_113592", "inhibitor" ], [ "species_76190", "inhibitor" ] ], "additional_components": [ "O42938", "SPBC16H5.02" ] }, "reaction_10729631": { "compartment": "compartment_70101", "id": "reaction_10729631", "reactome": "R-SPO-70262", "name": "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30533", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10729628", "catalyst" ] ], "additional_components": [ "Q9URZ7", "SPAC732.02c" ] }, "reaction_10729866": { "compartment": "compartment_5460", "id": "reaction_10729866", "reactome": "R-SPO-70501", "name": "Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29376", "species_113557", "species_113593" ], "products": [ "species_113548", "species_113581", "species_113587" ], "modifiers": [ [ "species_10729863", "catalyst" ], [ "species_113559", "catalyst" ] ], "additional_components": [ "Q9UUE1", "SPBC17G9.11c", "species_199207", "species_113527" ] }, "reaction_10729960": { "compartment": "compartment_70101", "id": "reaction_10729960", "reactome": "R-SPO-70592", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_29406" ], "products": [ "species_29404", "species_76213" ], "modifiers": [ [ "species_10729955", "catalyst" ] ], "additional_components": [ "O42652", "SPAC10F6.13c" ] }, "reaction_10730605": { "compartment": "compartment_70101", "id": "reaction_10730605", "reactome": "R-SPO-71802", "name": "D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30533" ], "modifiers": [ [ "species_10730602", "catalyst" ], [ "species_30533", "catalyst" ] ], "additional_components": [ "Q9UTK9", "SPAC144.17c", "Q9URZ7", "SPAC732.02c" ] }, "reaction_10741799": { "compartment": "compartment_12045", "id": "reaction_10741799", "reactome": "R-SPO-1482545", "name": "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741812": { "compartment": "compartment_12045", "id": "reaction_10741812", "reactome": "R-SPO-1482571", "name": "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10733703": { "compartment": "compartment_70101", "id": "reaction_10733703", "reactome": "R-SPO-109624", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500173", "species_113592" ], "products": [ "species_29370", "species_500088" ], "modifiers": [ [ "species_10733700", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:17256", "species_76577", "species_109386", "P78825", "SPCC338.14", "species_29926" ] }, "reaction_10732725": { "compartment": "compartment_70101", "id": "reaction_10732725", "reactome": "R-SPO-74213", "name": "APRT catalyzes the conversion of adenine to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_83951" ], "products": [ "species_111294", "species_76577" ], "modifiers": [ [ "species_10732722", "catalyst" ] ], "additional_components": [ "O42842", "SPAC23A1.03" ] }, "reaction_10733571": { "compartment": "compartment_70101", "id": "reaction_10733571", "reactome": "R-SPO-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76577", "species_29356" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10733568", "catalyst" ] ], "additional_components": [ "P50998", "SPBC106.04" ] }, "reaction_10734236": { "compartment": "compartment_70101", "id": "reaction_10734236", "reactome": "R-SPO-112033", "name": "PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113599", "species_500244" ], "products": [ "species_500172", "species_29372" ], "modifiers": [ [ "species_10732732", "catalyst" ] ], "additional_components": [ "species_112016", "CHEBI:58576", "CHEBI:28997", "CHEBI:17596", "Q9UTG1", "SPAC1805.16c" ] }, "reaction_10734238": { "compartment": "compartment_70101", "id": "reaction_10734238", "reactome": "R-SPO-112034", "name": "PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500244", "species_83956" ], "products": [ "species_500245", "species_29372" ], "modifiers": [ [ "species_10732732", "catalyst" ] ], "additional_components": [ "species_112016", "CHEBI:58576", "CHEBI:17172", "CHEBI:16750", "Q9UTG1", "SPAC1805.16c" ] }, "reaction_10742023": { "compartment": "compartment_12045", "id": "reaction_10742023", "reactome": "R-SPO-1482892", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741900": { "compartment": "compartment_12045", "id": "reaction_10741900", "reactome": "R-SPO-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10741895", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741999": { "compartment": "compartment_12045", "id": "reaction_10741999", "reactome": "R-SPO-1482828", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10741996", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742019": { "compartment": "compartment_12045", "id": "reaction_10742019", "reactome": "R-SPO-1482884", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741905": { "compartment": "compartment_12045", "id": "reaction_10741905", "reactome": "R-SPO-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10741895", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10749926": { "compartment": "compartment_70101", "id": "reaction_10749926", "reactome": "R-SPO-5694583", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694568" ], "products": [ "species_5694580", "species_5694567" ], "modifiers": [ [ "species_10749923", "catalyst" ] ], "additional_components": [ "SPAC6G10.03c" ] }, "reaction_10743442": { "compartment": "compartment_70101", "id": "reaction_10743442", "reactome": "R-SPO-2534096", "name": "METAP1/2 demethylates GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743423" ], "products": [ "species_174390", "species_10743408" ], "modifiers": [ [ "species_10743439", "catalyst" ] ], "additional_components": [ "SPAC23H3.13c", "SPAC23H3.13c", "O60085", "SPBC14C8.03", "O59730", "SPBC3E7.10", "species_880069" ] }, "reaction_10743483": { "compartment": "compartment_70101", "id": "reaction_10743483", "reactome": "R-SPO-2586748", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10743469" ], "products": [ "species_10743481" ], "modifiers": [], "additional_components": [ "SPAC18B11.04", "species_74016", "Q09711", "SPAC18B11.04" ] }, "reaction_10743421": { "compartment": "compartment_70101", "id": "reaction_10743421", "reactome": "R-SPO-2534087", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2534019", "species_10743408" ], "products": [ "species_76194", "species_10743411" ], "modifiers": [ [ "species_10743416", "catalyst" ] ], "additional_components": [ "SPAC23H3.13c", "SPAC23H3.13c", "SPBC2G2.11" ] }, "reaction_10737739": { "compartment": "compartment_70101", "id": "reaction_10737739", "reactome": "R-SPO-266072", "name": "LTA4 is hydolysed to LTB4 by LTA4H", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265281", "species_29356" ], "products": [ "species_266056" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10737682": { "compartment": "compartment_876", "id": "reaction_10737682", "reactome": "R-SPO-266012", "name": "LTD4 is converted to LTE4 by DPEP1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_266074" ], "products": [ "species_266029", "species_266033" ], "modifiers": [ [ "species_10737679", "catalyst" ] ], "additional_components": [ "O59832", "SPCC965.12", "species_442320", "O14124", "SPCC965.12" ] }, "reaction_10737721": { "compartment": "compartment_876", "id": "reaction_10737721", "reactome": "R-SPO-266046", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266013", "species_109276" ], "products": [ "species_210382", "species_266074" ], "modifiers": [ [ "species_10737718", "catalyst" ] ], "additional_components": [ "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10737729": { "compartment": "compartment_876", "id": "reaction_10737729", "reactome": "R-SPO-266070", "name": "LTC4 is exported from the cytosol by ABCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266066" ], "products": [ "species_266013" ], "modifiers": [ [ "species_10737726", "catalyst" ] ], "additional_components": [ "SPAC3F10.11c" ] }, "reaction_10731420": { "compartment": "compartment_7660", "id": "reaction_10731420", "reactome": "R-SPO-72185", "name": "mRNA polyadenylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731415", "species_29358" ], "products": [ "species_10731327", "species_10731322", "species_10731417", "species_10731317" ], "modifiers": [ [ "species_10731327", "catalyst" ] ], "additional_components": [ "Q9P7J4", "SPCC24B10.11c", "Q09176", "SPAP8A3.06", "O74733", "SPBC1709.08", "Q09801", "SPAC22G7.10", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q9HEQ9", "SPBC660.11", "O74740", "SPBC1709.15c", "Q10267", "SPAC13G7.03", "Q10295", "SPBC646.04", "P36629", "SPBC146.07", "O14327", "SPBC16E9.12c", "Q09779", "SPAC1D4.14", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9UTD1", "SPAC227.08c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "SPBC646.04", "SPBC16E9.12c", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "Q9P383", "SPBC13A2.01c", "C6Y4C0", "SPAC222.18", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "Q10267", "SPAC13G7.03", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "SPBC646.04" ] }, "reaction_10730232": { "compartment": "compartment_70101", "id": "reaction_10730232", "reactome": "R-SPO-71249", "name": "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31503" ], "products": [ "species_29424", "species_31311" ], "modifiers": [ [ "species_10730229", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c" ] }, "reaction_10750452": { "compartment": "compartment_17951", "id": "reaction_10750452", "reactome": "R-SPO-6787811", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787810", "species_113535" ], "products": [ "species_6787814", "species_113575" ], "modifiers": [ [ "species_10750449", "catalyst" ] ], "additional_components": [ "Q9HDX2", "SPAPB1A11.03" ] }, "reaction_10738303": { "compartment": "compartment_17951", "id": "reaction_10738303", "reactome": "R-SPO-389611", "name": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389594" ], "products": [ "species_389578", "species_389636" ], "modifiers": [ [ "species_10738300", "catalyst" ] ], "additional_components": [ "species_29480", "Q9Y7M1", "SPBC725.04", "species_29926" ] }, "reaction_10756425": { "compartment": "compartment_5460", "id": "reaction_10756425", "reactome": "R-SPO-8955817", "name": "PRODH2 oxidises HPRO to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215", "species_113597" ], "products": [ "species_164934", "species_113521", "species_113590" ], "modifiers": [ [ "species_10750340", "catalyst" ] ], "additional_components": [ "SPCC70.03c" ] }, "reaction_10730032": { "compartment": "compartment_5460", "id": "reaction_10730032", "reactome": "R-SPO-70670", "name": "PRODH oxidises L-Pro to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_379717", "species_113597" ], "products": [ "species_164934", "species_113529", "species_113590" ], "modifiers": [ [ "species_10730029", "catalyst" ] ], "additional_components": [ "SPCC70.03c" ] }, "reaction_10740192": { "compartment": "compartment_7660", "id": "reaction_10740192", "reactome": "R-SPO-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739886", "species_517622" ], "products": [ "species_10740190" ], "modifiers": [], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03" ] }, "reaction_10739891": { "compartment": "compartment_7660", "id": "reaction_10739891", "reactome": "R-SPO-450533", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10730941" ], "products": [ "species_113582", "species_10739886" ], "modifiers": [ [ "species_10739888", "catalyst" ] ], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "SPBC12D12.04c" ] }, "reaction_10739874": { "compartment": "compartment_7660", "id": "reaction_10739874", "reactome": "R-SPO-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450613", "species_10730941" ], "products": [ "species_10739872" ], "modifiers": [], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03" ] }, "reaction_10739908": { "compartment": "compartment_7660", "id": "reaction_10739908", "reactome": "R-SPO-450550", "name": "PKCalpha phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10730941" ], "products": [ "species_113582", "species_10739899" ], "modifiers": [ [ "species_10739905", "catalyst" ] ], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10740188": { "compartment": "compartment_7660", "id": "reaction_10740188", "reactome": "R-SPO-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739899", "species_450605" ], "products": [ "species_10740186" ], "modifiers": [], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03" ] }, "reaction_10729539": { "compartment": "compartment_7660", "id": "reaction_10729539", "reactome": "R-SPO-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10729536", "catalyst" ] ], "additional_components": [ "SPAC20G8.01" ] }, "reaction_10729463": { "compartment": "compartment_7660", "id": "reaction_10729463", "reactome": "R-SPO-69063", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729459", "species_29358", "species_10729450" ], "products": [ "species_113582", "species_10729461" ], "modifiers": [], "additional_components": [ "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09" ] }, "reaction_10729493": { "compartment": "compartment_7660", "id": "reaction_10729493", "reactome": "R-SPO-69074", "name": "Formation of Processive Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729465", "species_10729489" ], "products": [ "species_10729491" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "Q03392", "SPBC16D10.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10729502": { "compartment": "compartment_7660", "id": "reaction_10729502", "reactome": "R-SPO-69127", "name": "Formation of the Flap Intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729495" ], "products": [ "species_10729500" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10729467": { "compartment": "compartment_7660", "id": "reaction_10729467", "reactome": "R-SPO-69068", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729461" ], "products": [ "species_10729465", "species_10729448" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "Q03392", "SPBC16D10.09", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c" ] }, "reaction_10729517": { "compartment": "compartment_7660", "id": "reaction_10729517", "reactome": "R-SPO-69142", "name": "Recruitment of Dna2 endonuclease", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729506", "species_10729513" ], "products": [ "species_10729515" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "SPBC16D10.04c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "Q9URU2", "SPBC16D10.04c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c" ] }, "reaction_10729498": { "compartment": "compartment_7660", "id": "reaction_10729498", "reactome": "R-SPO-69116", "name": "Formation of Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729491" ], "products": [ "species_10729495" ], "modifiers": [ [ "species_10729489", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04" ] }, "reaction_10729508": { "compartment": "compartment_7660", "id": "reaction_10729508", "reactome": "R-SPO-69140", "name": "RPA binds to the Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729504", "species_10729500" ], "products": [ "species_10729506" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c" ] }, "reaction_10729531": { "compartment": "compartment_7660", "id": "reaction_10729531", "reactome": "R-SPO-69152", "name": "Removal of remaining Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729519" ], "products": [ "species_10729523" ], "modifiers": [ [ "species_10729528", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "SPAC3G6.06c" ] }, "reaction_10729521": { "compartment": "compartment_7660", "id": "reaction_10729521", "reactome": "R-SPO-69144", "name": "Removal of RNA primer and dissociation of RPA and Dna2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729515" ], "products": [ "species_418075", "species_29626", "species_418076", "species_10729504", "species_10729519", "species_164121", "species_10729513" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "Q9URU2", "SPBC16D10.04c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "SPBC16D10.04c" ] }, "reaction_10729452": { "compartment": "compartment_7660", "id": "reaction_10729452", "reactome": "R-SPO-69053", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729371", "species_10729448" ], "products": [ "species_10729450" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c" ] }, "reaction_10754222": { "compartment": "compartment_70101", "id": "reaction_10754222", "reactome": "R-SPO-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754218", "species_10754213" ], "products": [ "species_10754220" ], "modifiers": [], "additional_components": [ "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c" ] }, "reaction_10754274": { "compartment": "compartment_70101", "id": "reaction_10754274", "reactome": "R-SPO-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729165", "species_10754220" ], "products": [ "species_10754271" ], "modifiers": [ [ "species_10754220", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c" ] }, "reaction_10754276": { "compartment": "compartment_70101", "id": "reaction_10754276", "reactome": "R-SPO-8854044", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754271" ], "products": [ "species_10754213", "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10732603": { "compartment": "compartment_5460", "id": "reaction_10732603", "reactome": "R-SPO-73918", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73871", "species_113559" ], "products": [ "species_29374", "species_73917" ], "modifiers": [ [ "species_10732600", "catalyst" ] ], "additional_components": [ "SPAC4F8.14c" ] }, "reaction_10732595": { "compartment": "compartment_5460", "id": "reaction_10732595", "reactome": "R-SPO-73912", "name": "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73909", "species_29362", "species_113529" ], "products": [ "species_73911", "species_113526" ], "modifiers": [ [ "species_10732592", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10736725": { "compartment": "compartment_7660", "id": "reaction_10736725", "reactome": "R-SPO-199839", "name": "AKT can phosphorylate RSK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10736698" ], "products": [ "species_113582", "species_10736702" ], "modifiers": [ [ "species_10736722", "catalyst" ] ], "additional_components": [ "SPCC4G3.08", "SPCC4G3.08", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10756118": { "compartment": "compartment_70101", "id": "reaction_10756118", "reactome": "R-SPO-8948757", "name": "AKT phosphorylates MKRN1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741188" ], "products": [ "species_29370", "species_10756116" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "O74463", "SPCC1739.01", "P41000", "SPAC3A11.02", "O74463", "SPCC1739.01", "P41000", "SPAC3A11.02", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10743069": { "compartment": "compartment_70101", "id": "reaction_10743069", "reactome": "R-SPO-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737088", "species_179856" ], "products": [ "species_10743067" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_179856", "Q12701", "SPCC576.15c" ] }, "reaction_10752710": { "compartment": "compartment_70101", "id": "reaction_10752710", "reactome": "R-SPO-6807206", "name": "USP13 and OTUD3 deubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752707", "species_29356" ], "products": [ "species_10736691", "species_10729165" ], "modifiers": [ [ "species_10750094", "catalyst" ] ], "additional_components": [ "SPBC609.02", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC6B1.06c" ] }, "reaction_10752676": { "compartment": "compartment_70101", "id": "reaction_10752676", "reactome": "R-SPO-6807105", "name": "Monoubiquitinated PTEN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752670" ], "products": [ "species_10752674" ], "modifiers": [], "additional_components": [ "SPBC609.02", "SPBC609.02" ] }, "reaction_10753807": { "compartment": "compartment_70101", "id": "reaction_10753807", "reactome": "R-SPO-8850992", "name": "Proteasome degrades polyubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753805" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "O94526", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10753445": { "compartment": "compartment_70101", "id": "reaction_10753445", "reactome": "R-SPO-6811504", "name": "AKT1 dephosphorylation by PP2A-B56-beta,gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736495", "species_29356" ], "products": [ "species_10738388", "species_29372" ], "modifiers": [ [ "species_10753440", "catalyst" ], [ "species_1806240", "inhibitor" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10428", "SPCC188.02", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "P78759", "SPAC6F12.12" ] }, "reaction_10752688": { "compartment": "compartment_7660", "id": "reaction_10752688", "reactome": "R-SPO-6807126", "name": "Deubiquitinated PTEN translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752683" ], "products": [ "species_10736691" ], "modifiers": [], "additional_components": [ "SPBC609.02", "SPBC609.02" ] }, "reaction_10736540": { "compartment": "compartment_876", "id": "reaction_10736540", "reactome": "R-SPO-198314", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10736518" ], "products": [ "species_29370", "species_10736537" ], "modifiers": [ [ "species_10736518", "catalyst" ], [ "species_112275", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10736556": { "compartment": "compartment_70101", "id": "reaction_10736556", "reactome": "R-SPO-198609", "name": "AKT phosphorylates TSC2, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735151" ], "products": [ "species_29370", "species_10736554" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "SPAC630.13c", "SPAC630.13c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10753795": { "compartment": "compartment_70101", "id": "reaction_10753795", "reactome": "R-SPO-8850945", "name": "Casein kinase II phosphorylates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_113592" ], "products": [ "species_10753793", "species_29370" ], "modifiers": [ [ "species_10743403", "catalyst" ] ], "additional_components": [ "SPBC609.02", "SPBC609.02", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11" ] }, "reaction_10756085": { "compartment": "compartment_13231", "id": "reaction_10756085", "reactome": "R-SPO-8944457", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756078" ], "products": [ "species_10756076" ], "modifiers": [], "additional_components": [ "SPAC31G5.12c", "SPAC31G5.12c" ] }, "reaction_10752681": { "compartment": "compartment_70101", "id": "reaction_10752681", "reactome": "R-SPO-6807106", "name": "PTEN undergoes monoubiquitination", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_10729165" ], "products": [ "species_10752670" ], "modifiers": [ [ "species_10752678", "catalyst" ] ], "additional_components": [ "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC609.02", "Q9UTG2", "SPAC1805.15c", "O14064", "SPCC962.02c", "Q92462", "SPAC11G7.02", "O14326", "SPBC16E9.11c" ] }, "reaction_10736552": { "compartment": "compartment_70101", "id": "reaction_10736552", "reactome": "R-SPO-198599", "name": "AKT phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736545", "species_113592" ], "products": [ "species_29370", "species_10736549" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10756121": { "compartment": "compartment_70101", "id": "reaction_10756121", "reactome": "R-SPO-8948775", "name": "MKRN1 polyubiquitinates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_10729165" ], "products": [ "species_10752707" ], "modifiers": [ [ "species_10756116", "catalyst" ] ], "additional_components": [ "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC609.02", "O74463", "SPCC1739.01", "P41000", "SPAC3A11.02" ] }, "reaction_10752686": { "compartment": "compartment_7660", "id": "reaction_10752686", "reactome": "R-SPO-6807118", "name": "USP7 deubiquitinates monoubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752674", "species_113518" ], "products": [ "species_10752683", "species_10729044" ], "modifiers": [ [ "species_10747825", "catalyst" ] ], "additional_components": [ "SPBC609.02", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPCC188.08c" ] }, "reaction_10752704": { "compartment": "compartment_70101", "id": "reaction_10752704", "reactome": "R-SPO-6807134", "name": "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_10729165" ], "products": [ "species_10752691" ], "modifiers": [ [ "species_10752701", "catalyst" ] ], "additional_components": [ "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC609.02", "Q9UTG2", "SPAC1805.15c", "O14064", "SPCC962.02c", "Q92462", "SPAC11G7.02", "O14326", "SPBC16E9.11c" ] }, "reaction_10757421": { "compartment": "compartment_7660", "id": "reaction_10757421", "reactome": "R-SPO-9632910", "name": "ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744302" ], "products": [ "species_10736630" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "P27638", "SPAC31G5.09c" ] }, "reaction_10757419": { "compartment": "compartment_876", "id": "reaction_10757419", "reactome": "R-SPO-9632858", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10757406" ], "products": [ "species_29370", "species_10757416" ], "modifiers": [ [ "species_10757406", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "species_179838", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_179838", "P36582", "SPAC17G8.14c", "Q12701", "SPCC576.15c", "P36583", "SPBC12D12.04c", "species_179838", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c" ] }, "reaction_10744869": { "compartment": "compartment_7660", "id": "reaction_10744869", "reactome": "R-SPO-4570467", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744858" ], "products": [ "species_10743639", "species_10744867" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC23G3.06", "SPAC30D11.13", "O13351", "SPBC365.06", "Q9P7S7", "SPAC23G3.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744879": { "compartment": "compartment_7660", "id": "reaction_10744879", "reactome": "R-SPO-4570493", "name": "RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10730960" ], "products": [ "species_10743639", "species_10744877" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC3H8.09c", "SPAC30D11.13", "O13351", "SPBC365.06", "Q10145", "SPAC3H8.09c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10738944": { "compartment": "compartment_7660", "id": "reaction_10738944", "reactome": "R-SPO-427527", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10737547" ], "products": [ "species_77502", "species_10732938" ], "modifiers": [ [ "species_10738938", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "O94640", "SPBC16D10.07c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10257", "SPAC56F8.09", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c" ] }, "reaction_10738941": { "compartment": "compartment_7660", "id": "reaction_10738941", "reactome": "R-SPO-427514", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738924", "species_427523" ], "products": [ "species_427498", "species_427497", "species_10737547" ], "modifiers": [ [ "species_10738938", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "O94640", "SPBC16D10.07c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10257", "SPAC56F8.09", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c" ] }, "reaction_10735753": { "compartment": "compartment_7660", "id": "reaction_10735753", "reactome": "R-SPO-176956", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735739", "species_10735734", "species_10735749", "species_10735744" ], "products": [ "species_10735751" ], "modifiers": [], "additional_components": [ "SPBC725.13c", "SPBP23A10.09", "SPBP4H10.21c", "SPAC227.16c", "Q9UTC3", "SPAC227.16c", "O94329", "SPBC725.13c", "Q9P7X6", "SPBP23A10.09", "Q9P7C8", "SPBP4H10.21c" ] }, "reaction_10733255": { "compartment": "compartment_7660", "id": "reaction_10733255", "reactome": "R-SPO-75809", "name": "Phosphorylation of Cdc25C at Ser216 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732945", "species_29358" ], "products": [ "species_113582", "species_10732948" ], "modifiers": [ [ "species_10729617", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC14C4.03" ] }, "reaction_10757028": { "compartment": "compartment_70101", "id": "reaction_10757028", "reactome": "R-SPO-9029987", "name": "p-S216-CDC25C translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732948" ], "products": [ "species_10732952" ], "modifiers": [], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05" ] }, "reaction_10752429": { "compartment": "compartment_984", "id": "reaction_10752429", "reactome": "R-SPO-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752417" ], "products": [ "species_10752427" ], "modifiers": [], "additional_components": [ "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14098", "SPAC2F3.15", "O13864", "SPAC1B1.03c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "P05933", "SPAC3A12.14", "O94395", "SPCC126.02c", "Q9UUJ1", "SPAC11H11.06", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "O14008", "SPAC29A4.05", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "P27638", "SPAC31G5.09c", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "P32834", "SPAC26A3.01", "O74374", "SPBC32F12.10", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O43062", "SPBC4C3.09", "O13907", "SPAC22A12.16", "O94544", "SPCC1322.05c", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13", "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14098", "SPAC2F3.15", "O13864", "SPAC1B1.03c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "P05933", "SPAC3A12.14", "O94395", "SPCC126.02c", "Q9UUJ1", "SPAC11H11.06", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "O14008", "SPAC29A4.05", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "P27638", "SPAC31G5.09c", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "P32834", "SPAC26A3.01", "O74374", "SPBC32F12.10", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O43062", "SPBC4C3.09", "O13907", "SPAC22A12.16", "O94544", "SPCC1322.05c", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13" ] }, "reaction_10752526": { "compartment": "compartment_984", "id": "reaction_10752526", "reactome": "R-SPO-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752522", "species_181015" ], "products": [ "species_10752524" ], "modifiers": [], "additional_components": [ "SPAC57A10.09c", "P87057", "SPAC57A10.09c", "species_181015" ] }, "reaction_10752168": { "compartment": "compartment_6799351", "id": "reaction_10752168", "reactome": "R-SPO-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752152" ], "products": [ "species_10752166" ], "modifiers": [], "additional_components": [ "O13995", "SPAC25B8.01", "Q9P380", "SPBC13A2.04c", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O94296", "SPBC887.12", "Q9HFE5", "SPBP16F5.07", "Q9US20", "SPAC1851.02", "O59826", "SPCC965.06", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O59823", "SPCC965.03", "Q1MTQ5", "SPBC1773.11c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "O59715", "SPBC3B8.07c", "O42901", "SPBC119.09c", "Q09891", "SPAC24B11.12c", "O13995", "SPAC25B8.01", "Q9P380", "SPBC13A2.04c", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O94296", "SPBC887.12", "Q9HFE5", "SPBP16F5.07", "Q9US20", "SPAC1851.02", "O59826", "SPCC965.06", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O59823", "SPCC965.03", "Q1MTQ5", "SPBC1773.11c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "O59715", "SPBC3B8.07c", "O42901", "SPBC119.09c", "Q09891", "SPAC24B11.12c" ] }, "reaction_10741378": { "compartment": "compartment_70101", "id": "reaction_10741378", "reactome": "R-SPO-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741318", "species_113592", "species_10741312" ], "products": [ "species_10741349", "species_111294", "species_76577", "species_10741310" ], "modifiers": [ [ "species_10741318", "catalyst" ] ], "additional_components": [ "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q09760", "SPAC24H6.03", "P10505", "SPAC17C9.01c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O00102", "SPBP16F5.04", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q09760", "SPAC24H6.03", "P10505", "SPAC17C9.01c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01" ] }, "reaction_10752530": { "compartment": "compartment_984", "id": "reaction_10752530", "reactome": "R-SPO-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752522", "species_166005" ], "products": [ "species_10752528" ], "modifiers": [], "additional_components": [ "SPAC57A10.09c", "P87057", "SPAC57A10.09c", "species_166005" ] }, "reaction_10742867": { "compartment": "compartment_70101", "id": "reaction_10742867", "reactome": "R-SPO-2029456", "name": "RAC1 and CDC42 activate PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738332", "species_10738231" ], "products": [ "species_10742858", "species_10738330" ], "modifiers": [], "additional_components": [ "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "SPBC1604.14c" ] }, "reaction_10752267": { "compartment": "compartment_6800424", "id": "reaction_10752267", "reactome": "R-SPO-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752257" ], "products": [ "species_10752265" ], "modifiers": [], "additional_components": [ "P50515", "SPAC1B3.14", "Q9UUF7", "SPBC146.14c", "Q9P3W4", "SPAC458.04c", "Q9Y7J5", "SPBC1778.09", "Q9C0Y4", "SPAPB24D3.10c", "Q09914", "SPAC1F7.04", "O13742", "SPAC16E8.07c", "O13766", "SPAC17A5.04c", "O94323", "SPBC725.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q9C0W7", "SPBC691.03c", "Q9UR05", "SPAC926.07c", "P50515", "SPAC1B3.14", "Q9UUF7", "SPBC146.14c", "Q9P3W4", "SPAC458.04c", "Q9Y7J5", "SPBC1778.09", "Q9C0Y4", "SPAPB24D3.10c", "Q09914", "SPAC1F7.04", "O13742", "SPAC16E8.07c", "O13766", "SPAC17A5.04c", "O94323", "SPBC725.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q9C0W7", "SPBC691.03c", "Q9UR05", "SPAC926.07c" ] }, "reaction_10743526": { "compartment": "compartment_70101", "id": "reaction_10743526", "reactome": "R-SPO-2730835", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10737102" ], "products": [ "species_10743524", "species_29370" ], "modifiers": [], "additional_components": [ "species_112275", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "P36582", "SPAC17G8.14c" ] }, "reaction_10741650": { "compartment": "compartment_70101", "id": "reaction_10741650", "reactome": "R-SPO-1250280", "name": "ROS oxidize thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1250243", "species_10732350" ], "products": [ "species_10732348" ], "modifiers": [], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c" ] }, "reaction_10751591": { "compartment": "compartment_6800173", "id": "reaction_10751591", "reactome": "R-SPO-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751567" ], "products": [ "species_10751589" ], "modifiers": [], "additional_components": [ "Q10182", "SPAC3F10.07c", "Q09190", "SPAC1556.04c", "P32834", "SPAC26A3.01", "O74374", "SPBC32F12.10", "O13728", "SPAC15A10.08", "O14254", "SPAC6G10.08", "O94544", "SPCC1322.05c", "Q9P7E8", "SPAPJ760.02c", "O13986", "SPAC26H5.04", "Q10166", "SPAC26A3.11", "Q10182", "SPAC3F10.07c", "P32834", "SPAC26A3.01", "Q09190", "SPAC1556.04c", "O74374", "SPBC32F12.10", "O13728", "SPAC15A10.08", "O14254", "SPAC6G10.08", "O94544", "SPCC1322.05c", "Q9P7E8", "SPAPJ760.02c", "O13986", "SPAC26H5.04", "Q10166", "SPAC26A3.11" ] }, "reaction_10741390": { "compartment": "compartment_17957", "id": "reaction_10741390", "reactome": "R-SPO-983158", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983034" ], "products": [ "species_983033", "species_8943716" ], "modifiers": [ [ "species_10741385", "catalyst" ] ], "additional_components": [ "SPBC1921.05" ] }, "reaction_10737119": { "compartment": "compartment_876", "id": "reaction_10737119", "reactome": "R-SPO-202222", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10737102" ], "products": [ "species_29370", "species_10737116" ], "modifiers": [ [ "species_10737090", "catalyst" ] ], "additional_components": [ "species_112275", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "P36582", "SPAC17G8.14c", "species_202247", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10751415": { "compartment": "compartment_6798757", "id": "reaction_10751415", "reactome": "R-SPO-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751383" ], "products": [ "species_10751413" ], "modifiers": [], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q92356", "SPAC6G9.11", "O59866", "SPCC338.15", "O94296", "SPBC887.12", "O60119", "SPBC16G5.05c", "P50515", "SPAC1B3.14", "Q9USS6", "SPBC4.06", "Q9UT43", "SPBC887.12", "Q1MTQ5", "SPBC1773.11c", "Q8TFH3", "SPAPB17E12.11", "P17609", "SPAC9E9.07c", "O74786", "SPBC26H8.02c", "Q9URX4", "SPAC30D11.01c", "O13876", "SPAC1B3.11c", "Q09901", "SPAC30D11.01c", "O74559", "SPCC970.06", "Q9C0Y4", "SPAPB24D3.10c", "Q92356", "SPAC6G9.11", "O59866", "SPCC338.15", "O94296", "SPBC887.12", "O60119", "SPBC16G5.05c", "P50515", "SPAC1B3.14", "Q9USS6", "SPBC4.06", "Q9UT43", "SPBC887.12", "Q1MTQ5", "SPBC1773.11c", "Q8TFH3", "SPAPB17E12.11", "P17609", "SPAC9E9.07c", "O74786", "SPBC26H8.02c", "Q9URX4", "SPAC30D11.01c", "O13876", "SPAC1B3.11c", "Q09901", "SPAC30D11.01c", "O74559", "SPCC970.06" ] }, "reaction_10741351": { "compartment": "compartment_70101", "id": "reaction_10741351", "reactome": "R-SPO-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741349" ], "products": [ "species_983123", "species_10741221" ], "modifiers": [], "additional_components": [ "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10743820": { "compartment": "compartment_70101", "id": "reaction_10743820", "reactome": "R-SPO-3204303", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_874088", "species_10743816" ], "products": [ "species_10743818" ], "modifiers": [], "additional_components": [ "SPAC13C5.07", "Q09683", "SPAC13C5.07", "species_874088" ] }, "reaction_10745986": { "compartment": "compartment_876", "id": "reaction_10745986", "reactome": "R-SPO-5607734", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745398", "species_112275" ], "products": [ "species_10745984" ], "modifiers": [], "additional_components": [ "SPBC12D12.04c", "P36583", "SPBC12D12.04c", "species_112275" ] }, "reaction_10757837": { "compartment": "compartment_70101", "id": "reaction_10757837", "reactome": "R-SPO-9690461", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757816", "species_9678991" ], "products": [ "species_10757835" ], "modifiers": [], "additional_components": [ "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c", "species_9678991", "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c" ] }, "reaction_10741380": { "compartment": "compartment_70101", "id": "reaction_10741380", "reactome": "R-SPO-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741221", "species_10741312", "species_983035" ], "products": [ "species_10741314" ], "modifiers": [], "additional_components": [ "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O00102", "SPBP16F5.04", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9Y818", "SPBC1105.09", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q9P7R4", "SPBC211.07c", "Q09760", "SPAC24H6.03", "P23566", "SPAC18B11.07c", "P10505", "SPAC17C9.01c", "O00103", "SPCC1259.15c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O00102", "SPBP16F5.04", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "O74983", "SPCC338.05c", "Q09855", "SPAC29E6.01", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O94609", "SPBC1604.21c", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q9UTN8", "SPAC1250.03", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "O42646", "SPAC10F6.05c", "Q9P4W7", "SPAC959.09c", "O74549", "SPCC777.10c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01" ] }, "reaction_10751953": { "compartment": "compartment_1462052", "id": "reaction_10751953", "reactome": "R-SPO-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751817" ], "products": [ "species_10751951" ], "modifiers": [], "additional_components": [ "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "O42842", "SPAC23A1.03", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "Q9HGM8", "SPBC543.03c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "O14242", "SPAC6F6.11c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "O94395", "SPCC126.02c", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O74335", "SPBC17F3.01c", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O94466", "SPBC23G7.08c", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "Q10305", "SPAC22H10.12c", "O43062", "SPBC4C3.09", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13", "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "O42842", "SPAC23A1.03", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "Q9HGM8", "SPBC543.03c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "O14242", "SPAC6F6.11c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "O94395", "SPCC126.02c", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O74335", "SPBC17F3.01c", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O94466", "SPBC23G7.08c", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "Q10305", "SPAC22H10.12c", "O43062", "SPBC4C3.09", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13" ] }, "reaction_10738399": { "compartment": "compartment_70101", "id": "reaction_10738399", "reactome": "R-SPO-390329", "name": "Dephosphorylation of AKT by PP2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736505", "species_29356" ], "products": [ "species_10738396", "species_29372" ], "modifiers": [ [ "species_10738274", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10428", "SPCC188.02", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "P78759", "SPAC6F12.12" ] }, "reaction_10741612": { "compartment": "compartment_70101", "id": "reaction_10741612", "reactome": "R-SPO-1247960", "name": "Activation of p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741601" ], "products": [ "species_29370", "species_10741609" ], "modifiers": [ [ "species_10739738", "catalyst" ] ], "additional_components": [ "Q09892", "SPAC24B11.06c", "Q09892", "SPAC24B11.06c", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c" ] }, "reaction_10741353": { "compartment": "compartment_70101", "id": "reaction_10741353", "reactome": "R-SPO-983150", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983123" ], "products": [ "species_983032", "species_983036", "species_10729165", "species_8942986" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10742956": { "compartment": "compartment_161320", "id": "reaction_10742956", "reactome": "R-SPO-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10742951", "catalyst" ] ], "additional_components": [ "SPAC26A3.01" ] }, "reaction_10751977": { "compartment": "compartment_6799371", "id": "reaction_10751977", "reactome": "R-SPO-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751969" ], "products": [ "species_10751975" ], "modifiers": [], "additional_components": [ "P32834", "SPAC26A3.01", "O14242", "SPAC6F6.11c", "O13728", "SPAC15A10.08", "Q10166", "SPAC26A3.11", "O13864", "SPAC1B1.03c", "O13986", "SPAC26H5.04", "Q10066", "SPAC3H1.07", "P32834", "SPAC26A3.01", "O13728", "SPAC15A10.08", "O14242", "SPAC6F6.11c", "O13986", "SPAC26H5.04", "Q10166", "SPAC26A3.11", "O13864", "SPAC1B1.03c", "Q10066", "SPAC3H1.07" ] }, "reaction_10751653": { "compartment": "compartment_6799713", "id": "reaction_10751653", "reactome": "R-SPO-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751641" ], "products": [ "species_10751651" ], "modifiers": [], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q09706", "SPAC2F7.16c", "Q92356", "SPAC6G9.11", "O94296", "SPBC887.12", "Q9UR05", "SPAC926.07c", "P50515", "SPAC1B3.14", "O59826", "SPCC965.06", "Q9UUF7", "SPBC146.14c", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q09891", "SPAC24B11.12c", "Q9C0Y4", "SPAPB24D3.10c", "Q09706", "SPAC2F7.16c", "Q92356", "SPAC6G9.11", "O94296", "SPBC887.12", "Q9UR05", "SPAC926.07c", "P50515", "SPAC1B3.14", "O59826", "SPCC965.06", "Q9UUF7", "SPBC146.14c", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q09891", "SPAC24B11.12c" ] }, "reaction_10745990": { "compartment": "compartment_876", "id": "reaction_10745990", "reactome": "R-SPO-5607746", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745984" ], "products": [ "species_10745988" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "species_112275", "P36583", "SPBC12D12.04c", "species_112275" ] }, "reaction_10741530": { "compartment": "compartment_1222693", "id": "reaction_10741530", "reactome": "R-SPO-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10741527", "catalyst" ] ], "additional_components": [ "P50515", "SPAC1B3.14", "O43046", "SPBC3B9.18c", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O59823", "SPCC965.03", "O14046", "SPAC2C4.13", "O13742", "SPAC16E8.07c", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q69Z14", "SPBC1685.16", "Q9HDW6", "SPAPB2B4.05" ] }, "reaction_10741321": { "compartment": "compartment_70101", "id": "reaction_10741321", "reactome": "R-SPO-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741314" ], "products": [ "species_10741318", "species_111294", "species_76577", "species_10741310" ], "modifiers": [ [ "species_10741221", "catalyst" ] ], "additional_components": [ "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9Y818", "SPBC1105.09", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q9P7R4", "SPBC211.07c", "Q09760", "SPAC24H6.03", "P23566", "SPAC18B11.07c", "P10505", "SPAC17C9.01c", "O00103", "SPCC1259.15c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O00102", "SPBP16F5.04", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "O74983", "SPCC338.05c", "Q09855", "SPAC29E6.01", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O94609", "SPBC1604.21c", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q9UTN8", "SPAC1250.03", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "O42646", "SPAC10F6.05c", "Q9P4W7", "SPAC959.09c", "O74549", "SPCC777.10c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q09760", "SPAC24H6.03", "P10505", "SPAC17C9.01c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10740329": { "compartment": "compartment_70101", "id": "reaction_10740329", "reactome": "R-SPO-874087", "name": "SGT1 binds HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740325", "species_10740323" ], "products": [ "species_10740327" ], "modifiers": [], "additional_components": [ "SPAC926.04c", "SPBC36.12c", "P41887", "SPAC926.04c", "O59709", "SPBC36.12c" ] }, "reaction_10741337": { "compartment": "compartment_17957", "id": "reaction_10741337", "reactome": "R-SPO-983144", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983032", "species_113592", "species_29356" ], "products": [ "species_983034", "species_29370", "species_29372" ], "modifiers": [ [ "species_10741334", "catalyst" ] ], "additional_components": [ "P78966", "SPBC25B2.02c" ] }, "reaction_10742881": { "compartment": "compartment_876", "id": "reaction_10742881", "reactome": "R-SPO-2029471", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_29356" ], "products": [ "species_264618", "species_1602448" ], "modifiers": [ [ "species_10742876", "catalyst" ] ], "additional_components": [ "SPAC2F7.16c" ] }, "reaction_10737092": { "compartment": "compartment_70101", "id": "reaction_10737092", "reactome": "R-SPO-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737088", "species_202277" ], "products": [ "species_10737090" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_202247", "species_179838", "species_202247", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10752099": { "compartment": "compartment_1470028", "id": "reaction_10752099", "reactome": "R-SPO-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752055" ], "products": [ "species_10752097" ], "modifiers": [], "additional_components": [ "Q9UT70", "SPAC3G9.16c", "O74762", "SPBC17D11.07c", "O74557", "SPCC970.03", "Q9UUJ1", "SPAC11H11.06", "Q9P3A7", "SPAC1565.08", "P27638", "SPAC31G5.09c", "P05219", "SPBC26H8.07c", "O74490", "SPCC1442.17c", "O74492", "SPCC285.04", "Q9URZ0", "SPAC869.07c", "P78921", "SPBC337.05c", "Q10305", "SPAC22H10.12c", "O74498", "SPCC285.11", "P36621", "SPCC306.09c", "O74335", "SPBC17F3.01c", "O13907", "SPAC22A12.16", "P36583", "SPBC12D12.04c", "O14344", "SPBC2F12.14c", "P15258", "SPBC21.05c", "Q10147", "SPAC1D4.04", "O13290", "SPAC1093.06c", "Q09184", "SPAC23H4.09", "Q10066", "SPAC3H1.07", "Q9UUB5", "SPBC409.09c", "Q9UT70", "SPAC3G9.16c", "O74762", "SPBC17D11.07c", "O74557", "SPCC970.03", "Q9UUJ1", "SPAC11H11.06", "Q9P3A7", "SPAC1565.08", "P27638", "SPAC31G5.09c", "P05219", "SPBC26H8.07c", "O74490", "SPCC1442.17c", "O74492", "SPCC285.04", "Q9URZ0", "SPAC869.07c", "P78921", "SPBC337.05c", "Q10305", "SPAC22H10.12c", "O74498", "SPCC285.11", "P36621", "SPCC306.09c", "O74335", "SPBC17F3.01c", "O13907", "SPAC22A12.16", "P36583", "SPBC12D12.04c", "O14344", "SPBC2F12.14c", "P15258", "SPBC21.05c", "Q10147", "SPAC1D4.04", "O13290", "SPAC1093.06c", "Q09184", "SPAC23H4.09", "Q10066", "SPAC3H1.07", "Q9UUB5", "SPBC409.09c" ] }, "reaction_10741648": { "compartment": "compartment_70101", "id": "reaction_10741648", "reactome": "R-SPO-1250264", "name": "TXNIP binds reduced thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741644", "species_10732350" ], "products": [ "species_10741646" ], "modifiers": [], "additional_components": [ "Q09889", "SPCC584.15c", "O60150", "SPCC584.15c", "Q8WZK5", "SPCC584.15c", "Q10347", "SPCC584.15c", "Q09729", "SPCC584.15c", "O74798", "SPCC584.15c", "SPBC12D12.07c", "Q09889", "SPCC584.15c", "O60150", "SPCC584.15c", "Q8WZK5", "SPCC584.15c", "Q10347", "SPCC584.15c", "Q09729", "SPCC584.15c", "O94504", "SPBC12D12.07c", "O74798", "SPCC584.15c" ] }, "reaction_10742887": { "compartment": "compartment_70101", "id": "reaction_10742887", "reactome": "R-SPO-2029473", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737182", "species_10742885" ], "products": [ "species_10742765" ], "modifiers": [], "additional_components": [ "species_113592", "O60054", "SPBC56F2.03", "P10989", "SPBC32H8.12c", "P78774", "SPBC14C8.06", "Q10316", "SPAC17G8.04c", "Q9UUJ1", "SPAC11H11.06", "Q92352", "SPAC6G9.07c", "O60054", "SPBC56F2.03", "species_29370", "species_113592", "O14241", "SPAC6F6.10c", "P32390", "SPAC630.03", "Q9Y7J4", "SPBC1778.08c", "P10989", "SPBC32H8.12c", "P78774", "SPBC14C8.06", "Q10316", "SPAC17G8.04c", "Q9UUJ1", "SPAC11H11.06", "Q92352", "SPAC6G9.07c", "O14241", "SPAC6F6.10c", "species_113592", "O60054", "SPBC56F2.03", "P32390", "SPAC630.03", "Q9Y7J4", "SPBC1778.08c", "P10989", "SPBC32H8.12c" ] }, "reaction_10742865": { "compartment": "compartment_70101", "id": "reaction_10742865", "reactome": "R-SPO-2029454", "name": "Autophosphorylation of PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742858", "species_113592" ], "products": [ "species_29370", "species_10742862", "species_10738231" ], "modifiers": [ [ "species_10738330", "catalyst" ] ], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "SPBC1604.14c" ] }, "reaction_10741375": { "compartment": "compartment_70101", "id": "reaction_10741375", "reactome": "R-SPO-983153", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10729165", "species_29926", "species_10741367" ], "products": [ "species_10741369", "species_111294", "species_76577", "species_29926" ], "modifiers": [ [ "species_10741367", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O43069", "SPBC6B1.05c", "Q09765", "SPAC24H6.12c", "O94609", "SPBC1604.21c", "O43069", "SPBC6B1.05c", "P0CH07", "SPAC1805.12c", "Q09765", "SPAC24H6.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O43069", "SPBC6B1.05c", "Q09765", "SPAC24H6.12c", "O94609", "SPBC1604.21c" ] }, "reaction_10738619": { "compartment": "compartment_70101", "id": "reaction_10738619", "reactome": "R-SPO-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10738616", "catalyst" ] ], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01" ] }, "reaction_10743556": { "compartment": "compartment_70101", "id": "reaction_10743556", "reactome": "R-SPO-2730867", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743536" ], "products": [ "species_10743554" ], "modifiers": [], "additional_components": [ "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q12705", "SPBP4H10.04", "CHEBI:29034", "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "Q12705", "SPBP4H10.04", "O14008", "SPAC29A4.05", "CHEBI:29034" ] }, "reaction_10737443": { "compartment": "compartment_12045", "id": "reaction_10737443", "reactome": "R-SPO-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737349", "species_10737439" ], "products": [ "species_10737441" ], "modifiers": [], "additional_components": [ "Q01475", "SPBC31F10.06c", "species_29438", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q01475", "SPBC31F10.06c", "Q9USS7", "SPBC4.03c", "species_29438" ] }, "reaction_10741491": { "compartment": "compartment_70101", "id": "reaction_10741491", "reactome": "R-SPO-1168373", "name": "PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734514", "species_74016", "species_33625", "species_114519" ], "products": [ "species_10734538" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10751533": { "compartment": "compartment_876", "id": "reaction_10751533", "reactome": "R-SPO-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751485" ], "products": [ "species_10751531" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "Q9HDY0", "SPAPB1A10.10c", "Q9P3W4", "SPAC458.04c", "Q09914", "SPAC1F7.04", "Q10133", "SPAC16.01", "P17608", "SPAC4C5.02c", "Q9C0W7", "SPBC691.03c", "Q9HE04", "SPAC20H4.11c", "O94655", "SPBC405.04c", "Q9UUF7", "SPBC146.14c", "Q9USX1", "SPBC1921.05", "O13742", "SPAC16E8.07c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "O42901", "SPBC119.09c", "Q10201", "SPBC17D1.07c", "Q9HDY0", "SPAPB1A10.10c", "Q9P3W4", "SPAC458.04c", "Q09914", "SPAC1F7.04", "Q10133", "SPAC16.01", "P17608", "SPAC4C5.02c", "Q9C0W7", "SPBC691.03c", "Q9HE04", "SPAC20H4.11c", "O94655", "SPBC405.04c", "Q9UUF7", "SPBC146.14c", "Q9USX1", "SPBC1921.05", "O13742", "SPAC16E8.07c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "O42901", "SPBC119.09c" ] }, "reaction_10742874": { "compartment": "compartment_876", "id": "reaction_10742874", "reactome": "R-SPO-2029468", "name": "Conversion of PA into DAG by PAP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_29372", "species_112275" ], "modifiers": [ [ "species_10742869", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10737129": { "compartment": "compartment_70101", "id": "reaction_10737129", "reactome": "R-SPO-202328", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736928", "species_112275" ], "products": [ "species_10737127" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "P36582", "SPAC17G8.14c" ] }, "reaction_10741395": { "compartment": "compartment_70101", "id": "reaction_10741395", "reactome": "R-SPO-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983036" ], "products": [ "species_983032", "species_8942986" ], "modifiers": [ [ "species_10741392", "catalyst" ] ], "additional_components": [ "SPBC1921.05" ] }, "reaction_10741372": { "compartment": "compartment_70101", "id": "reaction_10741372", "reactome": "R-SPO-983152", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741369", "species_10741310" ], "products": [ "species_10741312", "species_10741367" ], "modifiers": [ [ "species_10741310", "catalyst" ] ], "additional_components": [ "O43069", "SPBC6B1.05c", "P0CH07", "SPAC1805.12c", "Q09765", "SPAC24H6.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O00102", "SPBP16F5.04", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O43069", "SPBC6B1.05c", "Q09765", "SPAC24H6.12c", "O94609", "SPBC1604.21c", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04" ] }, "reaction_10745417": { "compartment": "compartment_70101", "id": "reaction_10745417", "reactome": "R-SPO-5218813", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745410", "species_74016", "species_112275" ], "products": [ "species_10745415" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "species_74016", "P36582", "SPAC17G8.14c" ] }, "reaction_10737056": { "compartment": "compartment_70101", "id": "reaction_10737056", "reactome": "R-SPO-202127", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10737053", "catalyst" ], [ "species_5693375", "inhibitor" ] ], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "P36587", "SPBC29A10.01", "species_29870" ] }, "reaction_10737080": { "compartment": "compartment_70101", "id": "reaction_10737080", "reactome": "R-SPO-202137", "name": "AKT1 binds eNOS complex via HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737016", "species_10736495" ], "products": [ "species_10737024" ], "modifiers": [], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "P41887", "SPAC926.04c", "species_74016", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "O14008", "SPAC29A4.05", "P36587", "SPBC29A10.01", "species_113596", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "species_442320", "Q10364", "SPAC22E12.14c", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "P41887", "SPAC926.04c", "species_74016", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "O14008", "SPAC29A4.05", "P36587", "SPBC29A10.01", "P50530", "SPAC1B9.02c", "species_113596" ] }, "reaction_10745428": { "compartment": "compartment_876", "id": "reaction_10745428", "reactome": "R-SPO-5218821", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10745425" ], "products": [ "species_29370", "species_10745378" ], "modifiers": [ [ "species_10733716", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "SPCC576.15c" ] }, "reaction_10737051": { "compartment": "compartment_70101", "id": "reaction_10737051", "reactome": "R-SPO-202111", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10737024" ], "products": [ "species_29370", "species_10737049" ], "modifiers": [], "additional_components": [ "species_442320", "Q10364", "SPAC22E12.14c", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "P41887", "SPAC926.04c", "species_74016", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "O14008", "SPAC29A4.05", "P36587", "SPBC29A10.01", "P50530", "SPAC1B9.02c", "species_113596", "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_29870", "P36587", "SPBC29A10.01" ] }, "reaction_10742175": { "compartment": "compartment_70101", "id": "reaction_10742175", "reactome": "R-SPO-1497784", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_10737049" ], "products": [ "species_10737053" ], "modifiers": [], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_29870", "P36587", "SPBC29A10.01", "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "P36587", "SPBC29A10.01", "species_29870" ] }, "reaction_10745434": { "compartment": "compartment_876", "id": "reaction_10745434", "reactome": "R-SPO-5218823", "name": "PKC phosphorylates sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738404", "species_113592" ], "products": [ "species_29370", "species_10745431" ], "modifiers": [ [ "species_10745415", "catalyst" ] ], "additional_components": [ "SPAC4A8.07c", "SPAC4A8.07c", "P36583", "SPBC12D12.04c", "species_112275", "species_74016", "P36582", "SPAC17G8.14c" ] }, "reaction_10745413": { "compartment": "compartment_70101", "id": "reaction_10745413", "reactome": "R-SPO-5218805", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745378", "species_113592" ], "products": [ "species_29370", "species_10745410" ], "modifiers": [ [ "species_10745378", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10756127": { "compartment": "compartment_70616", "id": "reaction_10756127", "reactome": "R-SPO-8949580", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735134" ], "products": [ "species_10756125" ], "modifiers": [], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10743814": { "compartment": "compartment_7660", "id": "reaction_10743814", "reactome": "R-SPO-3108212", "name": "SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743242", "species_10743647" ], "products": [ "species_10743639", "species_10743780" ], "modifiers": [ [ "species_10743811", "catalyst" ] ], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "Q92380", "SPCC4E9.01c", "O13351", "SPBC365.06", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "P53692", "SPCC5E4.06", "O13710", "SPAC14C4.02c", "Q6BDR8", "SPBC20F10.04c", "Q4PIR3", "SPAC16A10.06c", "Q9Y7U4", "SPCC645.04", "Q53EK2", "SPCC550.05" ] }, "reaction_10744821": { "compartment": "compartment_7660", "id": "reaction_10744821", "reactome": "R-SPO-4551648", "name": "SUMOylation of TDG with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10733857" ], "products": [ "species_10743639", "species_10744819" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPCC965.05c", "SPAC30D11.13", "O13351", "SPBC365.06", "O59825", "SPCC965.05c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744848": { "compartment": "compartment_7660", "id": "reaction_10744848", "reactome": "R-SPO-4568863", "name": "SUMOylation of RAD52 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733420", "species_10743647" ], "products": [ "species_10743639", "species_10744846" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC30D11.10", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P36592", "SPAC30D11.10", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744919": { "compartment": "compartment_7660", "id": "reaction_10744919", "reactome": "R-SPO-4570554", "name": "SUMOylation of MDC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744909", "species_10743647" ], "products": [ "species_10743639", "species_10744917" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPACUNK4.14", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O14079", "SPACUNK4.14", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744904": { "compartment": "compartment_7660", "id": "reaction_10744904", "reactome": "R-SPO-4570528", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744894", "species_10743647" ], "products": [ "species_10743639", "species_10744902" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPCC4G3.10c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P87235", "SPCC4G3.10c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10730240": { "compartment": "compartment_70101", "id": "reaction_10730240", "reactome": "R-SPO-71286", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_30401" ], "products": [ "species_70106", "species_71285", "species_29916" ], "modifiers": [ [ "species_10730237", "catalyst" ] ], "additional_components": [ "SPAC26A3.17c" ] }, "reaction_10753723": { "compartment": "compartment_12045", "id": "reaction_10753723", "reactome": "R-SPO-8848582", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848577", "species_200993" ], "products": [ "species_76194", "species_8848499" ], "modifiers": [ [ "species_10749964", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10753726": { "compartment": "compartment_12045", "id": "reaction_10753726", "reactome": "R-SPO-8848585", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30209", "species_200993" ], "products": [ "species_76194", "species_2534407" ], "modifiers": [ [ "species_10749964", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10749962": { "compartment": "compartment_12045", "id": "reaction_10749962", "reactome": "R-SPO-5696424", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696426", "species_192172" ], "products": [ "species_162743", "species_5696412" ], "modifiers": [ [ "species_10749959", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10734474": { "compartment": "compartment_7660", "id": "reaction_10734474", "reactome": "R-SPO-113504", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729371" ], "products": [ "species_113656", "species_10728742" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c" ] }, "reaction_10756722": { "compartment": "compartment_70101", "id": "reaction_10756722", "reactome": "R-SPO-9013024", "name": "RHOB binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756718", "species_10756713" ], "products": [ "species_10756720" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "P36583", "SPBC12D12.04c", "P78953", "SPCC4B3.15", "Q92356", "SPAC6G9.11", "O14188", "SPAC4F8.13c", "O74786", "SPBC26H8.02c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "O43027", "SPBC354.13", "Q10133", "SPAC16.01", "species_29438", "Q9P3B1", "SPAC1565.02c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "O74786", "SPBC26H8.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c" ] }, "reaction_10756711": { "compartment": "compartment_70101", "id": "reaction_10756711", "reactome": "R-SPO-9013021", "name": "GDIs block activation of RHOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756705", "species_10756703" ], "products": [ "species_10756709" ], "modifiers": [], "additional_components": [ "SPAC6F12.06", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O14224", "SPAC6F12.06" ] }, "reaction_10756716": { "compartment": "compartment_70101", "id": "reaction_10756716", "reactome": "R-SPO-9013022", "name": "RHOB GAPs stimulate RHOB GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756713", "species_29356" ], "products": [ "species_29372", "species_10756703" ], "modifiers": [ [ "species_10756508", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757839": { "compartment": "compartment_876", "id": "reaction_10757839", "reactome": "R-SPO-9690494", "name": "RHOB translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756713" ], "products": [ "species_10746731" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10737802": { "compartment": "compartment_70101", "id": "reaction_10737802", "reactome": "R-SPO-350598", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468" ], "products": [ "species_113528", "species_351164" ], "modifiers": [ [ "species_10737799", "catalyst" ] ], "additional_components": [ "SPAC144.04c" ] }, "reaction_10740399": { "compartment": "compartment_5460", "id": "reaction_10740399", "reactome": "R-SPO-916855", "name": "PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_916850" ], "products": [ "species_113552", "species_880046" ], "modifiers": [ [ "species_10740396", "catalyst" ] ], "additional_components": [ "CHEBI:33739", "O13837", "SPAC19D5.07" ] }, "reaction_10740363": { "compartment": "compartment_5460", "id": "reaction_10740363", "reactome": "R-SPO-888548", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_880046", "species_113526" ], "products": [ "species_113536", "species_29362", "species_113529" ], "modifiers": [ [ "species_10740360", "catalyst" ] ], "additional_components": [ "Q9US47", "SPAC1002.12c" ] }, "reaction_10735650": { "compartment": "compartment_7660", "id": "reaction_10735650", "reactome": "R-SPO-174451", "name": "Recruitment of DNA2 endonuclease to the C strand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735624", "species_10729513" ], "products": [ "species_10735626" ], "modifiers": [], "additional_components": [ "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "O14246", "SPAC6F6.16c", "Q96TL7", "SPBC1778.02", "P87324", "SPAC27E2.05", "CHEBI:15986", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "O13988", "SPAC26H5.06", "Q92372", "SPBC660.13c", "SPBC16D10.04c", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "O14246", "SPAC6F6.16c", "Q96TL7", "SPBC1778.02", "P87324", "SPAC27E2.05", "Q9URU2", "SPBC16D10.04c", "CHEBI:15986", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "O13988", "SPAC26H5.06", "Q92372", "SPBC660.13c" ] }, "reaction_10732942": { "compartment": "compartment_350", "id": "reaction_10732942", "reactome": "R-SPO-74986", "name": "Elongation of pre-rRNA transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_74985" ], "products": [ "species_74985" ], "modifiers": [ [ "species_10732500", "catalyst" ], [ "species_10732940", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "O94703", "SPCC1259.03", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O14086", "SPAC2F3.03c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "Q9UST5", "SPBC336.09c", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "Q9P7X8", "SPBP23A10.07", "O74366", "SPBC30B4.07c", "O43036", "SPBC3B9.07c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P40381", "SPAC664.01c", "P04909", "SPCC622.08c", "Q10103", "SPAC18G6.02c", "O42934", "SPBC16C6.10" ] }, "reaction_10732415": { "compartment": "compartment_7660", "id": "reaction_10732415", "reactome": "R-SPO-73757", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732406", "species_10732411" ], "products": [ "species_10732413" ], "modifiers": [], "additional_components": [ "O94703", "SPCC1259.03", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "O94616", "SPBC1289.07c", "O14086", "SPAC2F3.03c", "Q92399", "SPBC14C8.12", "Q9P7X8", "SPBP23A10.07", "O13877", "SPAC1B3.12c", "O43036", "SPBC3B9.07c", "SPAC18G6.11c", "O94703", "SPCC1259.03", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P15398", "SPBC4C3.05c", "Q10110", "SPAC18G6.11c", "P48011", "SPBC19C2.03", "O94616", "SPBC1289.07c", "O14086", "SPAC2F3.03c", "Q92399", "SPBC14C8.12", "Q9P7X8", "SPBP23A10.07", "O13877", "SPAC1B3.12c", "O43036", "SPBC3B9.07c" ] }, "reaction_10732502": { "compartment": "compartment_7660", "id": "reaction_10732502", "reactome": "R-SPO-73769", "name": "Loss of Rrn3 from RNA Polymerase I promoter escape complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732496" ], "products": [ "species_10732411", "species_10732500" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "O94703", "SPCC1259.03", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "Q10110", "SPAC18G6.11c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O14086", "SPAC2F3.03c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "Q9UST5", "SPBC336.09c", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "Q9P7X8", "SPBP23A10.07", "O74366", "SPBC30B4.07c", "O43036", "SPBC3B9.07c", "SPAC18G6.11c", "P36613", "SPBP16F5.02", "O94703", "SPCC1259.03", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O14086", "SPAC2F3.03c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "Q9UST5", "SPBC336.09c", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "Q9P7X8", "SPBP23A10.07", "O74366", "SPBC30B4.07c", "O43036", "SPBC3B9.07c" ] }, "reaction_10739704": { "compartment": "compartment_5460", "id": "reaction_10739704", "reactome": "R-SPO-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_159450" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10739701", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "P19117", "SPAC23C11.05" ] }, "reaction_10735146": { "compartment": "compartment_5460", "id": "reaction_10735146", "reactome": "R-SPO-164840", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_10735134", "species_113581" ], "products": [ "species_10735136" ], "modifiers": [], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "species_29370", "Q09774", "SPAC22F3.07c", "species_29372", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10735144": { "compartment": "compartment_5460", "id": "reaction_10735144", "reactome": "R-SPO-164834", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735138", "species_163953" ], "products": [ "species_10735134", "species_113529", "species_113593" ], "modifiers": [ [ "species_10735138", "catalyst" ] ], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "species_113592", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "species_113592", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10735141": { "compartment": "compartment_5460", "id": "reaction_10735141", "reactome": "R-SPO-164832", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735136" ], "products": [ "species_10735138", "species_113521" ], "modifiers": [ [ "species_10735136", "catalyst" ] ], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "species_29370", "Q09774", "SPAC22F3.07c", "species_29372", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "species_113592", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "species_29370", "Q09774", "SPAC22F3.07c", "species_29372", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10756939": { "compartment": "compartment_876", "id": "reaction_10756939", "reactome": "R-SPO-9018798", "name": "RHOV binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756937" ], "products": [ "species_10756922", "species_29420" ], "modifiers": [], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "Q01112", "SPAC110.03", "species_29438" ] }, "reaction_10756935": { "compartment": "compartment_876", "id": "reaction_10756935", "reactome": "R-SPO-9018794", "name": "RHOV binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756931", "species_10756922" ], "products": [ "species_10756933" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USZ0", "SPBC1306.02", "O43125", "SPBC119.05c", "Q10056", "SPAC1F5.09c", "Q9USR1", "SPBC577.08c", "Q01112", "SPAC110.03", "O13728", "SPAC15A10.08", "O14188", "SPAC4F8.13c", "O94466", "SPBC23G7.08c", "Q02088", "SPAC27F1.02c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10161", "SPAC26A3.05", "Q9USZ0", "SPBC1306.02", "O43125", "SPBC119.05c", "Q10056", "SPAC1F5.09c", "Q9USR1", "SPBC577.08c", "Q01112", "SPAC110.03", "O13728", "SPAC15A10.08", "O14188", "SPAC4F8.13c", "O94466", "SPBC23G7.08c", "Q02088", "SPAC27F1.02c", "species_29438", "P50527", "SPBC1604.14c" ] }, "reaction_10752666": { "compartment": "compartment_12045", "id": "reaction_10752666", "reactome": "R-SPO-6807053", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_6807054", "species_29368" ], "products": [ "species_29366", "species_6807057", "species_29356" ], "modifiers": [ [ "species_10736341", "catalyst" ] ], "additional_components": [ "O13666", "SPBC27B12.03c", "O94457", "SPAC1687.16c" ] }, "reaction_10743177": { "compartment": "compartment_1598585", "id": "reaction_10743177", "reactome": "R-SPO-2466068", "name": "Phosphorylation of cohesin by PLK1 at chromosomal arms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10743162" ], "products": [ "species_29370", "species_10743174" ], "modifiers": [ [ "species_10738046", "catalyst" ] ], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "O94383", "SPBC29A10.04", "P30776", "SPCC338.17c", "O94364", "SPBC428.17c", "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "Q9HFF5", "SPAC110.02", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c", "SPAC23C11.16" ] }, "reaction_10755724": { "compartment": "compartment_5460", "id": "reaction_10755724", "reactome": "R-SPO-8878815", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755715", "species_10755703" ], "products": [ "species_10755701", "species_10755717" ], "modifiers": [ [ "species_10755722", "catalyst" ] ], "additional_components": [ "P78859", "SPCC645.03c", "O43045", "SPBC3B9.17", "Q9HDW8", "SPAPB2B4.02", "CHEBI:33739", "SPAPB2B4.02", "CHEBI:49883", "P78859", "SPCC645.03c", "O43045", "SPBC3B9.17", "SPAC144.08" ] }, "reaction_10743108": { "compartment": "compartment_5460", "id": "reaction_10743108", "reactome": "R-SPO-2395517", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_113529", "species_10743106" ], "products": [ "species_113563", "species_10743104" ], "modifiers": [], "additional_components": [ "O59710", "SPBC3B8.01c", "species_113596", "O59710", "SPBC3B8.01c", "species_31649" ] }, "reaction_10741701": { "compartment": "compartment_5460", "id": "reaction_10741701", "reactome": "R-SPO-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741699", "species_113531" ], "products": [ "species_10741697" ], "modifiers": [], "additional_components": [ "Q9UTC6", "SPAC227.13c", "O74831", "SPCC1183.03c", "O60068", "SPBC13G1.06c", "O74351", "SPBC21D10.11c", "Q9UTC6", "SPAC227.13c", "O74831", "SPCC1183.03c", "O60068", "SPBC13G1.06c", "O74351", "SPBC21D10.11c", "species_113531" ] }, "reaction_10754910": { "compartment": "compartment_12045", "id": "reaction_10754910", "reactome": "R-SPO-8867876", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_392417" ], "products": [ "species_1806234", "species_33625" ], "modifiers": [ [ "species_10754907", "catalyst" ] ], "additional_components": [ "O74178", "SPBC1271.12", "O94512", "SPBC646.08c", "O43021", "SPBC354.07c", "Q9UUA1", "SPCC23B6.01c" ] }, "reaction_10742025": { "compartment": "compartment_12045", "id": "reaction_10742025", "reactome": "R-SPO-1482897", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498722", "species_1524021" ], "modifiers": [ [ "species_10741988", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741912": { "compartment": "compartment_12045", "id": "reaction_10741912", "reactome": "R-SPO-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498722", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741897": { "compartment": "compartment_12045", "id": "reaction_10741897", "reactome": "R-SPO-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498724", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741983": { "compartment": "compartment_12045", "id": "reaction_10741983", "reactome": "R-SPO-1482771", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498724", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10729620": { "compartment": "compartment_7660", "id": "reaction_10729620", "reactome": "R-SPO-69608", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10729577" ], "products": [ "species_113582", "species_10729589" ], "modifiers": [ [ "species_10729617", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC14C4.03" ] }, "reaction_10729587": { "compartment": "compartment_70101", "id": "reaction_10729587", "reactome": "R-SPO-69600", "name": "Proteolytic degradation of ubiquitinated-Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729585" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P06652", "SPAC24H6.05", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10729608": { "compartment": "compartment_7660", "id": "reaction_10729608", "reactome": "R-SPO-69604", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10729577" ], "products": [ "species_113582", "species_10729589" ], "modifiers": [ [ "species_10729605", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "O13945", "SPAC23H4.02", "O74536", "SPCC74.03c" ] }, "reaction_10742125": { "compartment": "compartment_70616", "id": "reaction_10742125", "reactome": "R-SPO-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110577", "species_1524101" ], "products": [ "species_1524064", "species_159450" ], "modifiers": [ [ "species_10742122", "catalyst" ] ], "additional_components": [ "SPBC13A2.03" ] }, "reaction_10743262": { "compartment": "compartment_7660", "id": "reaction_10743262", "reactome": "R-SPO-2468040", "name": "Cohesin binds PDS5 and WAPAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743242", "species_10743244", "species_10743248" ], "products": [ "species_10743250" ], "modifiers": [], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "SPAC110.02", "SPBC428.17c", "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c" ] }, "reaction_10734651": { "compartment": "compartment_7660", "id": "reaction_10734651", "reactome": "R-SPO-156723", "name": "Regulation of KIF20A (MKL2) by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10734646" ], "products": [ "species_113582", "species_10734649" ], "modifiers": [ [ "species_10734620", "catalyst" ] ], "additional_components": [ "SPBC15D4.01c", "SPBC15D4.01c", "SPAC23C11.16" ] }, "reaction_10743288": { "compartment": "compartment_1598585", "id": "reaction_10743288", "reactome": "R-SPO-2470935", "name": "Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2537690", "species_10743250", "species_10743280" ], "products": [ "species_10743286" ], "modifiers": [], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c", "O94459", "SPAC1687.18c", "Q09725", "SPAC31A2.05c", "Q92380", "SPCC4E9.01c", "O94459", "SPAC1687.18c", "O42649", "SPAC10F6.09c", "Q09725", "SPAC31A2.05c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c" ] }, "reaction_10734623": { "compartment": "compartment_7660", "id": "reaction_10734623", "reactome": "R-SPO-156673", "name": "Regulation of KIF23 (MKLP1) by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10734610" ], "products": [ "species_113582", "species_10734614" ], "modifiers": [ [ "species_10734620", "catalyst" ] ], "additional_components": [ "SPBC15D4.01c", "SPBC15D4.01c", "SPAC23C11.16" ] }, "reaction_10752664": { "compartment": "compartment_5460", "id": "reaction_10752664", "reactome": "R-SPO-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807477", "species_113593" ], "products": [ "species_113548", "species_113600", "species_113581", "species_113529" ], "modifiers": [ [ "species_10752661", "catalyst" ] ], "additional_components": [ "SPCC61.03" ] }, "reaction_10752656": { "compartment": "compartment_5460", "id": "reaction_10752656", "reactome": "R-SPO-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10752653", "catalyst" ] ], "additional_components": [ "O13725", "SPAC15A10.05c" ] }, "reaction_10753139": { "compartment": "compartment_17951", "id": "reaction_10753139", "reactome": "R-SPO-6809287", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389620", "species_141343", "species_192305" ], "products": [ "species_6809289", "species_193465" ], "modifiers": [ [ "species_10753136", "catalyst" ] ], "additional_components": [ "SPBC1778.03c" ] }, "reaction_10757787": { "compartment": "compartment_7660", "id": "reaction_10757787", "reactome": "R-SPO-9671145", "name": "DKC1 binds SHQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757783", "species_10734902" ], "products": [ "species_10757785" ], "modifiers": [], "additional_components": [ "SPBC8D2.13", "SPAC29A4.04c", "O43076", "SPBC8D2.13", "O14007", "SPAC29A4.04c" ] }, "reaction_10753499": { "compartment": "compartment_70101", "id": "reaction_10753499", "reactome": "R-SPO-6814119", "name": "TRiC/CCT binds unfolded G-protein beta subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738448", "species_10753491" ], "products": [ "species_10753497" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "SPBC32H8.07", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10753507": { "compartment": "compartment_70101", "id": "reaction_10753507", "reactome": "R-SPO-6814124", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753497" ], "products": [ "species_29370", "species_10753503" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_113592", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10738452": { "compartment": "compartment_70101", "id": "reaction_10738452", "reactome": "R-SPO-391266", "name": "Association of CCT/TriC with sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738448", "species_10738404" ], "products": [ "species_10738450" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "SPAC4A8.07c", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "O14159", "SPAC4A8.07c", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10753505": { "compartment": "compartment_70101", "id": "reaction_10753505", "reactome": "R-SPO-6814120", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753503" ], "products": [ "species_29372", "species_10753497" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_113592", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10752940": { "compartment": "compartment_6791047", "id": "reaction_10752940", "reactome": "R-SPO-6807877", "name": "ARFGAPs stimulate ARF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752857" ], "products": [ "species_10752937", "species_10752792", "species_10746137", "species_10752725" ], "modifiers": [ [ "species_10752857", "catalyst" ] ], "additional_components": [ "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "O13728", "SPAC15A10.08", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O60073", "SPBC13G1.11", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "O13932", "SPAC23C4.13", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "Q09857", "SPAC29E6.03c", "O13946", "SPAC23H4.03c", "O13728", "SPAC15A10.08", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "O42937", "SPBC16C6.13c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "O60073", "SPBC13G1.11", "Q9P7I9", "SPCC24B10.17", "O13932", "SPAC23C4.13", "P11620", "SPBC1703.10", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "Q09857", "SPAC29E6.03c", "SPAC22E12.17c", "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "O13728", "SPAC15A10.08", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O60073", "SPBC13G1.11", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "O13932", "SPAC23C4.13", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "Q09857", "SPAC29E6.03c" ] }, "reaction_10753303": { "compartment": "compartment_12045", "id": "reaction_10753303", "reactome": "R-SPO-6811425", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753301", "species_10739129", "species_10749814" ], "products": [ "species_10753292" ], "modifiers": [], "additional_components": [ "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "O13785", "SPAC17G6.07c", "O42852", "SPAC23A1.15c", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "Q9P4X4", "SPAC959.02", "O13785", "SPAC17G6.07c", "Q9P7Q4", "SPAC1834.11c", "O42852", "SPAC23A1.15c" ] }, "reaction_10749851": { "compartment": "compartment_6791047", "id": "reaction_10749851", "reactome": "R-SPO-5694423", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10749847", "species_10749814" ], "products": [ "species_10749849" ], "modifiers": [], "additional_components": [ "SPAC959.02", "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P7Q4", "SPAC1834.11c", "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10754292": { "compartment": "compartment_17938", "id": "reaction_10754292", "reactome": "R-SPO-8854255", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754282", "species_29356" ], "products": [ "species_29372", "species_10754284" ], "modifiers": [ [ "species_10754282", "catalyst" ], [ "species_10754290", "catalyst" ] ], "additional_components": [ "O94655", "SPBC405.04c", "CHEBI:15996", "species_29420", "O94655", "SPBC405.04c", "O94655", "SPBC405.04c", "CHEBI:15996", "SPAC4G8.04" ] }, "reaction_10740660": { "compartment": "compartment_70101", "id": "reaction_10740660", "reactome": "R-SPO-917700", "name": "MVB Vesicle Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740430", "species_10740658" ], "products": [ "species_10740526", "species_10740656" ], "modifiers": [], "additional_components": [ "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "P0CH07", "SPAC1805.12c", "O74967", "SPBC4B4.06", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O43038", "SPBC3B9.09", "species_179838", "O94663", "SPBC651.05c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "P0C8R3", "SPAC589.10c", "O14296", "SPAC9E9.14", "species_179838", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "P0CH06", "SPAC11G7.04", "O74967", "SPBC4B4.06", "O43038", "SPBC3B9.09", "O94663", "SPBC651.05c" ] }, "reaction_10753584": { "compartment": "compartment_6791047", "id": "reaction_10753584", "reactome": "R-SPO-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753579" ], "products": [ "species_10749719", "species_10753577" ], "modifiers": [ [ "species_10753579", "catalyst" ] ], "additional_components": [ "P11620", "SPBC1703.10", "species_29438", "O94661", "SPBC651.03c", "species_29420", "P11620", "SPBC1703.10", "SPBC651.03c", "P11620", "SPBC1703.10", "species_29438", "O94661", "SPBC651.03c" ] }, "reaction_10754588": { "compartment": "compartment_876", "id": "reaction_10754588", "reactome": "R-SPO-8862280", "name": "FCHo proteins bind nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754497", "species_10754509", "species_10754481", "species_10754426", "species_10754471", "species_10754491" ], "products": [ "species_10754511" ], "modifiers": [], "additional_components": [ "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "species_179856", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "Q9USZ7", "SPBC11G11.02c", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "O94685", "SPBC83.01", "Q9USZ7", "SPBC11G11.02c", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "O94685", "SPBC83.01", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "Q9USZ7", "SPBC11G11.02c", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "O94685", "SPBC83.01", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q9Y7L6", "SPBC685.04c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_179856", "O94685", "SPBC83.01" ] }, "reaction_10755426": { "compartment": "compartment_876", "id": "reaction_10755426", "reactome": "R-SPO-8871196", "name": "Initial binding of AP-2 and clathrin to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754388", "species_10738801", "species_179856" ], "products": [ "species_10754497" ], "modifiers": [], "additional_components": [ "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "species_179856" ] }, "reaction_10753408": { "compartment": "compartment_263163", "id": "reaction_10753408", "reactome": "R-SPO-6811428", "name": "RIC1:RGP1 recruits RAB6:GDP to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753400", "species_10753388" ], "products": [ "species_10753406" ], "modifiers": [], "additional_components": [ "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "species_29420", "P17608", "SPAC4C5.02c", "species_29420", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c" ] }, "reaction_10753602": { "compartment": "compartment_263163", "id": "reaction_10753602", "reactome": "R-SPO-8847534", "name": "RAB43 hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753595" ], "products": [ "species_10753599" ], "modifiers": [ [ "species_10753595", "catalyst" ] ], "additional_components": [ "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "species_29438", "species_29420", "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "species_29438" ] }, "reaction_10755664": { "compartment": "compartment_13946", "id": "reaction_10755664", "reactome": "R-SPO-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755636" ], "products": [ "species_10755437", "species_10755646", "species_29420" ], "modifiers": [ [ "species_10755661", "catalyst" ] ], "additional_components": [ "species_29420", "P11620", "SPBC1703.10", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P11620", "SPBC1703.10", "species_29438", "O74748", "SPBC1734.07c", "O14251", "SPAC6G10.05c", "Q9UT70", "SPAC3G9.16c", "Q9USZ5", "SPBC11G11.04", "Q9P6P5", "SPAC644.18c", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O13732", "SPAC15A10.12c", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12" ] }, "reaction_10753415": { "compartment": "compartment_263163", "id": "reaction_10753415", "reactome": "R-SPO-6811429", "name": "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10753406" ], "products": [ "species_29420", "species_10753412" ], "modifiers": [ [ "species_10753406", "catalyst" ] ], "additional_components": [ "species_29420", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c", "species_29438", "species_29420", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c" ] }, "reaction_10755452": { "compartment": "compartment_216813", "id": "reaction_10755452", "reactome": "R-SPO-8875318", "name": "RAB3 GEFs exchange GTP for GDP on RAB3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755439" ], "products": [ "species_10755437", "species_10755447", "species_29420" ], "modifiers": [ [ "species_10755449", "catalyst" ] ], "additional_components": [ "species_29420", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17609", "SPAC9E9.07c", "species_29438", "O13876", "SPAC1B3.11c", "SPAC23C4.10" ] }, "reaction_10755040": { "compartment": "compartment_876", "id": "reaction_10755040", "reactome": "R-SPO-8868651", "name": "Endophilins recruit synaptojanins to the clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755020", "species_10742387" ], "products": [ "species_10755033" ], "modifiers": [], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856", "SPBC2G2.02", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10753710": { "compartment": "compartment_20699", "id": "reaction_10753710", "reactome": "R-SPO-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753701" ], "products": [ "species_10753707" ], "modifiers": [ [ "species_10753701", "catalyst" ] ], "additional_components": [ "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753246": { "compartment": "compartment_20699", "id": "reaction_10753246", "reactome": "R-SPO-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10753235" ], "products": [ "species_10753239", "species_29420" ], "modifiers": [ [ "species_10753235", "catalyst" ] ], "additional_components": [ "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10754846": { "compartment": "compartment_876", "id": "reaction_10754846", "reactome": "R-SPO-8867613", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738025", "species_10754842" ], "products": [ "species_10754844" ], "modifiers": [], "additional_components": [ "SPAC6G9.11", "O60167", "SPBC19F8.03c", "Q92356", "SPAC6G9.11", "O60167", "SPBC19F8.03c" ] }, "reaction_10753617": { "compartment": "compartment_20699", "id": "reaction_10753617", "reactome": "R-SPO-8847638", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753612" ], "products": [ "species_29370", "species_10753102", "species_10739129", "species_10753091", "species_10749814", "species_10753100", "species_10753002" ], "modifiers": [ [ "species_10753612", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "SPBC8D2.14c", "SPAC959.02", "SPAC4G8.10", "Q9P7Q4", "SPAC1834.11c", "Q09730", "SPAC31A2.13c", "O13932", "SPAC23C4.13", "SPBC13G1.11", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10737431": { "compartment": "compartment_70101", "id": "reaction_10737431", "reactome": "R-SPO-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10737423" ], "products": [ "species_10737349", "species_29420" ], "modifiers": [ [ "species_10737428", "catalyst" ] ], "additional_components": [ "species_29420", "Q01475", "SPBC31F10.06c", "Q01475", "SPBC31F10.06c", "species_29438", "SPBC3H7.01" ] }, "reaction_10749854": { "compartment": "compartment_6791047", "id": "reaction_10749854", "reactome": "R-SPO-5694425", "name": "NSF ATPase activity dissociates cis-SNARE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10749849" ], "products": [ "species_10749821", "species_10749837", "species_10739129", "species_10749828", "species_10749814", "species_10749845", "species_29372", "species_10749823" ], "modifiers": [ [ "species_10749849", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "SPAC23C4.13", "O13644", "SPBC8D2.14c", "O94651", "SPBC31E1.04", "SPAC959.02", "SPCC74.01", "Q9P7Q4", "SPAC1834.11c", "O60073", "SPBC13G1.11", "Q9Y7L0", "SPBC2A9.08c", "SPAP14E8.03", "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10753581": { "compartment": "compartment_6791047", "id": "reaction_10753581", "reactome": "R-SPO-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753577", "species_10749883" ], "products": [ "species_10753579" ], "modifiers": [], "additional_components": [ "SPBC651.03c", "P11620", "SPBC1703.10", "species_29438", "P11620", "SPBC1703.10", "species_29438", "O94661", "SPBC651.03c" ] }, "reaction_10754326": { "compartment": "compartment_17938", "id": "reaction_10754326", "reactome": "R-SPO-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10754316" ], "products": [ "species_10754318", "species_29372" ], "modifiers": [ [ "species_10754316", "catalyst" ], [ "species_10754324", "catalyst" ] ], "additional_components": [ "O94655", "SPBC405.04c", "Q9HDY0", "SPAPB1A10.10c", "CHEBI:15996", "O94655", "SPBC405.04c", "Q9HDY0", "SPAPB1A10.10c", "species_111349", "O94655", "SPBC405.04c", "Q9HDY0", "SPAPB1A10.10c", "CHEBI:15996", "SPAC630.05" ] }, "reaction_10753567": { "compartment": "compartment_263163", "id": "reaction_10753567", "reactome": "R-SPO-6814684", "name": "cis-SNARE binds SNAPs and NSF hexamer at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10753563", "species_10749814" ], "products": [ "species_10753565" ], "modifiers": [], "additional_components": [ "SPAC959.02", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q9P6P1", "SPAC823.05c", "Q9P7Q4", "SPAC1834.11c", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c" ] }, "reaction_10752744": { "compartment": "compartment_6791047", "id": "reaction_10752744", "reactome": "R-SPO-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10752737" ], "products": [ "species_29370", "species_10752741" ], "modifiers": [ [ "species_10752737", "catalyst" ] ], "additional_components": [ "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10754916": { "compartment": "compartment_876", "id": "reaction_10754916", "reactome": "R-SPO-8868072", "name": "Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10754884", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9USP6", "SPBC9B6.08", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10757826": { "compartment": "compartment_70101", "id": "reaction_10757826", "reactome": "R-SPO-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754388", "species_9648300" ], "products": [ "species_10754724" ], "modifiers": [], "additional_components": [ "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_9648300", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10754525": { "compartment": "compartment_876", "id": "reaction_10754525", "reactome": "R-SPO-8856813", "name": "AAK1 phosphorylates AP-2 mu subunit at T156", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10754515" ], "products": [ "species_29370", "species_10754522" ], "modifiers": [ [ "species_10754515", "catalyst" ] ], "additional_components": [ "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_179856", "O94685", "SPBC83.01", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O94685", "SPBC83.01", "species_179856", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_179856", "O94685", "SPBC83.01", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02" ] }, "reaction_10755038": { "compartment": "compartment_876", "id": "reaction_10755038", "reactome": "R-SPO-8868648", "name": "SYNJ hydrolyze PI(4,5)P2 to PI(4)P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755033", "species_29356" ], "products": [ "species_29372", "species_10755035" ], "modifiers": [ [ "species_10755033", "catalyst" ] ], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "species_1806234", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "species_29438", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10749891": { "compartment": "compartment_6791047", "id": "reaction_10749891", "reactome": "R-SPO-5694441", "name": "CSNK1D phosphorylates SEC23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10749871" ], "products": [ "species_29370", "species_10749807", "species_10737297", "species_10749877", "species_10749883", "species_10749768", "species_10749875" ], "modifiers": [ [ "species_10749888", "catalyst" ] ], "additional_components": [ "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q10149", "SPAC1D4.02c", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15", "Q09857", "SPAC29E6.03c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13637", "SPBC8D2.20c", "O94319", "SPBC215.15", "P87109", "SPAC20G8.02", "O13644", "SPBC8D2.14c", "O60073", "SPBC13G1.11", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q10149", "SPAC1D4.02c", "Q9Y7L0", "SPBC2A9.08c", "Q9USS7", "SPBC4.03c", "Q09857", "SPAC29E6.03c", "P11620", "SPBC1703.10", "species_29438", "O14251", "SPAC6G10.05c", "Q9UT70", "SPAC3G9.16c", "Q9USZ5", "SPBC11G11.04", "Q9P6P5", "SPAC644.18c", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O13732", "SPAC15A10.12c", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "SPCC31H12.07", "SPBC3H7.15" ] }, "reaction_10737888": { "compartment": "compartment_70101", "id": "reaction_10737888", "reactome": "R-SPO-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10737859" ], "products": [ "species_10737863", "species_29420" ], "modifiers": [ [ "species_10737885", "catalyst" ] ], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "P36579", "SPBC4F6.18c", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753554": { "compartment": "compartment_263163", "id": "reaction_10753554", "reactome": "R-SPO-6814676", "name": "SNAPs and NSF hexamer bind cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10753550", "species_10749814" ], "products": [ "species_10753552" ], "modifiers": [], "additional_components": [ "SPAC959.02", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P6P1", "SPAC823.05c", "Q9P7Q4", "SPAC1834.11c", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c" ] }, "reaction_10753606": { "compartment": "compartment_263163", "id": "reaction_10753606", "reactome": "R-SPO-8847537", "name": "RAB43:GTP binds USP8NL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753593", "species_10753604" ], "products": [ "species_10753595" ], "modifiers": [], "additional_components": [ "P11620", "SPBC1703.10", "species_29438", "SPAC26F1.09", "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "species_29438" ] }, "reaction_10755079": { "compartment": "compartment_24339", "id": "reaction_10755079", "reactome": "R-SPO-8868658", "name": "HSPA8-mediated ATP hydrolysis promotes vesicle uncoating", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755070", "species_29356" ], "products": [ "species_10755072", "species_10755076", "species_29372" ], "modifiers": [ [ "species_10755070", "catalyst" ] ], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q10265", "SPAC13G7.02c", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "species_29370", "Q10265", "SPAC13G7.02c", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q10265", "SPAC13G7.02c", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10749918": { "compartment": "compartment_70101", "id": "reaction_10749918", "reactome": "R-SPO-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737373" ], "products": [ "species_10737439", "species_29372", "species_10737371", "species_10737423" ], "modifiers": [ [ "species_10737373", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9USS7", "SPBC4.03c", "species_29420", "Q01475", "SPBC31F10.06c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438" ] }, "reaction_10753635": { "compartment": "compartment_20699", "id": "reaction_10753635", "reactome": "R-SPO-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742399", "species_10753631" ], "products": [ "species_10753633" ], "modifiers": [], "additional_components": [ "P36579", "SPBC4F6.18c", "CHEBI:15996", "O42903", "SPBC119.12", "O60109", "SPBC14F5.13c", "O42903", "SPBC119.12", "P36579", "SPBC4F6.18c", "O60109", "SPBC14F5.13c", "CHEBI:15996" ] }, "reaction_10752733": { "compartment": "compartment_6791047", "id": "reaction_10752733", "reactome": "R-SPO-6807864", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752729", "species_10749883", "species_10752725" ], "products": [ "species_10752731" ], "modifiers": [], "additional_components": [ "Q09857", "SPAC29E6.03c", "P11620", "SPBC1703.10", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753120": { "compartment": "compartment_20699", "id": "reaction_10753120", "reactome": "R-SPO-6809014", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10749814", "species_10753116" ], "products": [ "species_10753118" ], "modifiers": [], "additional_components": [ "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10753237": { "compartment": "compartment_20699", "id": "reaction_10753237", "reactome": "R-SPO-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746137", "species_10753233" ], "products": [ "species_10753235" ], "modifiers": [], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753123": { "compartment": "compartment_20699", "id": "reaction_10753123", "reactome": "R-SPO-6809015", "name": "NSF ATPase activity dissociates cis-SNARE at cis-Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753118", "species_113592" ], "products": [ "species_10753102", "species_10753106", "species_10753091", "species_29372", "species_10753100", "species_10753074", "species_10753002" ], "modifiers": [ [ "species_10753118", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "SPBC8D2.14c", "SPAP14E8.03", "SPAC4G8.10", "Q09730", "SPAC31A2.13c", "O13932", "SPAC23C4.13", "SPAC23C4.13", "SPBC13G1.11", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10753260": { "compartment": "compartment_20699", "id": "reaction_10753260", "reactome": "R-SPO-6811417", "name": "ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752792", "species_10753256", "species_10753241", "species_10753250", "species_10753070" ], "products": [ "species_10753258" ], "modifiers": [], "additional_components": [ "SPAC22E12.17c", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P36579", "SPBC4F6.18c", "P87140", "SPAC57A7.10c", "P11620", "SPBC1703.10", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "SPBC2A9.08c", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06" ] }, "reaction_10737445": { "compartment": "compartment_12045", "id": "reaction_10737445", "reactome": "R-SPO-204008", "name": "SEC31:SEC13 and v-SNARE recruitment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737297", "species_10737379", "species_10737310" ], "products": [ "species_10737381" ], "modifiers": [], "additional_components": [ "O13637", "SPBC8D2.20c", "O94319", "SPBC215.15", "P87109", "SPAC20G8.02", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "O14029", "SPAC29B12.07", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O60073", "SPBC13G1.11", "Q9Y7L0", "SPBC2A9.08c", "O13637", "SPBC8D2.20c", "O14029", "SPAC29B12.07", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "P87109", "SPAC20G8.02", "O13644", "SPBC8D2.14c", "O60073", "SPBC13G1.11", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O94319", "SPBC215.15" ] }, "reaction_10754333": { "compartment": "compartment_5683628", "id": "reaction_10754333", "reactome": "R-SPO-8854588", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747277", "species_10754329" ], "products": [ "species_10754331" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "SPAC630.05", "O94272", "SPBP8B7.24c", "Q9UUH7", "SPAC630.05" ] }, "reaction_10754886": { "compartment": "compartment_876", "id": "reaction_10754886", "reactome": "R-SPO-8867756", "name": "CLASP proteins and cargo are recruited to the nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754878", "species_10754522" ], "products": [ "species_10754880" ], "modifiers": [], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9P7V2", "SPAC30.04c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O94685", "SPBC83.01", "species_179856", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9USP6", "SPBC9B6.08", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10755085": { "compartment": "compartment_24339", "id": "reaction_10755085", "reactome": "R-SPO-8868659", "name": "Clathrin recruits auxilins to the clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755081", "species_10739268" ], "products": [ "species_10755083" ], "modifiers": [], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "SPAC17A5.12", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10749791": { "compartment": "compartment_12045", "id": "reaction_10749791", "reactome": "R-SPO-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737367", "species_10737361", "species_10737369" ], "products": [ "species_10737371" ], "modifiers": [], "additional_components": [ "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "Q9P7G5", "SPAP14E8.03", "SPCC31H12.07", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9USS7", "SPBC4.03c" ] }, "reaction_10754599": { "compartment": "compartment_70101", "id": "reaction_10754599", "reactome": "R-SPO-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754595", "species_10749451" ], "products": [ "species_10754591" ], "modifiers": [], "additional_components": [ "SPAC31A2.09c", "SPBC12D12.08c", "SPAC31A2.09c" ] }, "reaction_10753248": { "compartment": "compartment_20699", "id": "reaction_10753248", "reactome": "R-SPO-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753032", "species_10752725" ], "products": [ "species_10753233" ], "modifiers": [], "additional_components": [ "P11620", "SPBC1703.10", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10738021": { "compartment": "compartment_70101", "id": "reaction_10738021", "reactome": "R-SPO-376364", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738012", "species_10738014", "species_10738010" ], "products": [ "species_10738012", "species_10738016", "species_10738010" ], "modifiers": [ [ "species_10738018", "catalyst" ] ], "additional_components": [ "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "Q92356", "SPAC6G9.11", "O74786", "SPBC26H8.02c", "Q9USH7", "SPCC825.03c" ] }, "reaction_10753384": { "compartment": "compartment_12045", "id": "reaction_10753384", "reactome": "R-SPO-6811427", "name": "COPI vesicle uncoating at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753382" ], "products": [ "species_10753301", "species_10749719", "species_10753380", "species_10752783", "species_10753346" ], "modifiers": [], "additional_components": [ "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "O42852", "SPAC23A1.15c", "O42937", "SPBC16C6.13c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "P11620", "SPBC1703.10", "Q9C0W8", "SPBC691.02c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O13785", "SPAC17G6.07c", "O74559", "SPCC970.06", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "O13785", "SPAC17G6.07c", "O42852", "SPAC23A1.15c", "species_29420", "P11620", "SPBC1703.10", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "O42937", "SPBC16C6.13c", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c" ] }, "reaction_10755090": { "compartment": "compartment_876", "id": "reaction_10755090", "reactome": "R-SPO-8868661", "name": "Dynamin-mediated GTP hydrolysis promotes vesicle scission", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10755035" ], "products": [ "species_10755081", "species_29372" ], "modifiers": [ [ "species_10755035", "catalyst" ] ], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "species_1806234", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "species_29438", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "species_1806234", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "species_29438", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10753713": { "compartment": "compartment_20699", "id": "reaction_10753713", "reactome": "R-SPO-8848484", "name": "PLA2s hydrolyze phospholipids at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_29356" ], "products": [ "species_6814303", "species_8848483" ], "modifiers": [ [ "species_10739104", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10740639": { "compartment": "compartment_74700", "id": "reaction_10740639", "reactome": "R-SPO-917693", "name": "ESCRT Disassembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740526", "species_113592" ], "products": [ "species_10740409", "species_29370", "species_10740404", "species_10740428", "species_10740414", "species_10740423", "species_29372", "species_10740620" ], "modifiers": [ [ "species_10740636", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "P0C8R3", "SPAC589.10c", "O14296", "SPAC9E9.14", "species_179838", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "P0CH06", "SPAC11G7.04", "SPAC9E9.14", "SPAC4F8.01", "SPCC162.06c", "SPAC1142.07c", "SPBC215.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "species_179838", "P0CH06", "SPAC11G7.04", "O74422", "SPCC162.06c", "Q09803", "SPAC2G11.06", "O13703", "SPAC13F5.04c" ] }, "reaction_10753614": { "compartment": "compartment_20699", "id": "reaction_10753614", "reactome": "R-SPO-8847637", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10749814", "species_10753610" ], "products": [ "species_10753612" ], "modifiers": [], "additional_components": [ "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10749856": { "compartment": "compartment_13959", "id": "reaction_10749856", "reactome": "R-SPO-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749719", "species_10749768", "species_10737419" ], "products": [ "species_10749770" ], "modifiers": [], "additional_components": [ "species_29420", "P11620", "SPBC1703.10", "O14251", "SPAC6G10.05c", "Q9UT70", "SPAC3G9.16c", "Q9USZ5", "SPBC11G11.04", "Q9P6P5", "SPAC644.18c", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O13732", "SPAC15A10.12c", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "O60073", "SPBC13G1.11", "O13637", "SPBC8D2.20c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O94319", "SPBC215.15", "P87109", "SPAC20G8.02", "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "species_29420", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "Q09784", "SPAC13G6.05c", "P11620", "SPBC1703.10", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15" ] }, "reaction_10753557": { "compartment": "compartment_263163", "id": "reaction_10753557", "reactome": "R-SPO-6814678", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753552", "species_113592" ], "products": [ "species_10753539", "species_29370", "species_10739129", "species_10753544", "species_10753548", "species_10753546", "species_10749814" ], "modifiers": [ [ "species_10753552", "catalyst" ] ], "additional_components": [ "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c", "SPBC36B7.07", "SPAC959.02", "SPAC823.05c", "SPAC6G9.11", "SPBC3B9.10", "Q9P7Q4", "SPAC1834.11c", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c" ] }, "reaction_10753703": { "compartment": "compartment_20699", "id": "reaction_10753703", "reactome": "R-SPO-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742399", "species_10753667" ], "products": [ "species_10753701" ], "modifiers": [], "additional_components": [ "P36579", "SPBC4F6.18c", "CHEBI:15996", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10749795": { "compartment": "compartment_12045", "id": "reaction_10749795", "reactome": "R-SPO-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737433", "species_10737302", "species_10737369" ], "products": [ "species_10749793" ], "modifiers": [], "additional_components": [ "SPAC22F8.08", "SPBC2A9.08c", "SPCC31H12.07", "O74873", "SPCC31H12.07", "Q9Y7L0", "SPBC2A9.08c", "Q9UUI5", "SPAC22F8.08" ] }, "reaction_10752739": { "compartment": "compartment_6791047", "id": "reaction_10752739", "reactome": "R-SPO-6807866", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746137", "species_10752731" ], "products": [ "species_10752737" ], "modifiers": [], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10754348": { "compartment": "compartment_262783", "id": "reaction_10754348", "reactome": "R-SPO-8854759", "name": "TBC1D14 binds RAB11 and ULK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754344", "species_10754335", "species_10754339" ], "products": [ "species_10754346" ], "modifiers": [], "additional_components": [ "SPAC23D3.03c", "SPAC18G6.03", "SPCC63.08c", "P17610", "SPAC18G6.03", "Q9Y7T4", "SPCC63.08c", "Q09844", "SPAC23D3.03c" ] }, "reaction_10749777": { "compartment": "compartment_13959", "id": "reaction_10749777", "reactome": "R-SPO-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10749770" ], "products": [ "species_10749774", "species_29420" ], "modifiers": [ [ "species_10749770", "catalyst" ] ], "additional_components": [ "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "species_29420", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "Q09784", "SPAC13G6.05c", "P11620", "SPBC1703.10", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15", "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15", "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "species_29420", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "Q09784", "SPAC13G6.05c", "P11620", "SPBC1703.10", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15" ] }, "reaction_10754306": { "compartment": "compartment_262783", "id": "reaction_10754306", "reactome": "R-SPO-8854293", "name": "TBC1D10A (EPI64) binds ARF6:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754295", "species_10754302" ], "products": [ "species_10754304" ], "modifiers": [], "additional_components": [ "SPBC1778.09", "Q9Y7Z2", "SPBC1539.08", "species_29438", "Q9Y7J5", "SPBC1778.09", "Q9Y7Z2", "SPBC1539.08", "species_29438" ] }, "reaction_10755558": { "compartment": "compartment_263163", "id": "reaction_10755558", "reactome": "R-SPO-8876193", "name": "RIC1-RGP1 exchanges GTP for GDP on RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755545" ], "products": [ "species_10755437", "species_10755549", "species_29420" ], "modifiers": [ [ "species_10755555", "catalyst" ] ], "additional_components": [ "species_29420", "P17608", "SPAC4C5.02c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17608", "SPAC4C5.02c", "species_29438", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c" ] }, "reaction_10745653": { "compartment": "compartment_263163", "id": "reaction_10745653", "reactome": "R-SPO-5333658", "name": "CLAT:AP1:CLVS bind PI(3,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745649", "species_5334668" ], "products": [ "species_10745651" ], "modifiers": [], "additional_components": [ "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UU81", "SPCP1E11.06", "Q9HFE5", "SPBP16F5.07", "O43079", "SPBC947.02", "Q9P7N2", "SPAP27G11.06c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "species_6809774", "Q9UU81", "SPCP1E11.06", "Q9HFE5", "SPBP16F5.07", "O43079", "SPBC947.02", "Q9P7N2", "SPAP27G11.06c" ] }, "reaction_10753295": { "compartment": "compartment_12045", "id": "reaction_10753295", "reactome": "R-SPO-6811422", "name": "NSF ATPase activity dissociates cis-SNARE at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753292" ], "products": [ "species_10753288", "species_10753278", "species_10739129", "species_10753283", "species_10737302", "species_10749814", "species_29372" ], "modifiers": [ [ "species_10753292", "catalyst" ] ], "additional_components": [ "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "Q9P4X4", "SPAC959.02", "O13785", "SPAC17G6.07c", "Q9P7Q4", "SPAC1834.11c", "O42852", "SPAC23A1.15c", "SPAC17G6.07c", "SPAC23A1.15c", "SPAC959.02", "SPCC895.04c", "SPBC2A9.08c", "Q9P7Q4", "SPAC1834.11c", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "Q9P4X4", "SPAC959.02", "O13785", "SPAC17G6.07c", "Q9P7Q4", "SPAC1834.11c", "O42852", "SPAC23A1.15c" ] }, "reaction_10755022": { "compartment": "compartment_876", "id": "reaction_10755022", "reactome": "R-SPO-8868236", "name": "BAR domain proteins recruit dynamin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755018", "species_10755016" ], "products": [ "species_10755020" ], "modifiers": [], "additional_components": [ "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "species_29438", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q9P6L5", "SPAC688.11", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10738030": { "compartment": "compartment_876", "id": "reaction_10738030", "reactome": "R-SPO-376369", "name": "Vamp2 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738012", "species_10738023", "species_10738010" ], "products": [ "species_10738012", "species_10738025", "species_10738010" ], "modifiers": [ [ "species_10738027", "catalyst" ] ], "additional_components": [ "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "Q92356", "SPAC6G9.11", "O74786", "SPBC26H8.02c", "Q9USH7", "SPCC825.03c" ] }, "reaction_10754913": { "compartment": "compartment_876", "id": "reaction_10754913", "reactome": "R-SPO-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10742317", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10753273": { "compartment": "compartment_20699", "id": "reaction_10753273", "reactome": "R-SPO-6811418", "name": "ARFGAPs stimulate ARF GTPase activity at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753258" ], "products": [ "species_10752792", "species_10746137", "species_10752725", "species_10753270" ], "modifiers": [ [ "species_10753258", "catalyst" ] ], "additional_components": [ "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "SPAC22E12.17c", "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "O42937", "SPBC16C6.13c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06" ] }, "reaction_10755570": { "compartment": "compartment_70101", "id": "reaction_10755570", "reactome": "R-SPO-8876446", "name": "p-ULK1 phosphorylates DENND3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755563", "species_113592" ], "products": [ "species_29370", "species_10755567" ], "modifiers": [ [ "species_10746793", "catalyst" ] ], "additional_components": [ "SPCC297.05", "SPCC297.05", "SPCC63.08c" ] }, "reaction_10753243": { "compartment": "compartment_20699", "id": "reaction_10753243", "reactome": "R-SPO-6811412", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752783", "species_10753239" ], "products": [ "species_10753241" ], "modifiers": [], "additional_components": [ "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "O42937", "SPBC16C6.13c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P36579", "SPBC4F6.18c", "P87140", "SPAC57A7.10c", "P11620", "SPBC1703.10", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10755087": { "compartment": "compartment_24339", "id": "reaction_10755087", "reactome": "R-SPO-8868660", "name": "Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755083", "species_10755046" ], "products": [ "species_10755070" ], "modifiers": [], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_113592", "Q10265", "SPAC13G7.02c", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q10265", "SPAC13G7.02c", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10754726": { "compartment": "compartment_876", "id": "reaction_10754726", "reactome": "R-SPO-8866277", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754388", "species_10754720" ], "products": [ "species_10754722" ], "modifiers": [ [ "species_10754724", "inhibitor" ] ], "additional_components": [ "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q92337", "SPAC9E9.12c", "O74852", "SPCC18.02", "Q9P7V2", "SPAC30.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9P7V2", "SPAC30.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_9648300", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10749915": { "compartment": "compartment_12045", "id": "reaction_10749915", "reactome": "R-SPO-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737349", "species_10737439", "species_10737371" ], "products": [ "species_10737373" ], "modifiers": [], "additional_components": [ "Q01475", "SPBC31F10.06c", "species_29438", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438" ] }, "reaction_10755587": { "compartment": "compartment_262783", "id": "reaction_10755587", "reactome": "R-SPO-8876454", "name": "DENND3 exchanges GTP for GDP on RAB12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755574" ], "products": [ "species_10755437", "species_10755582", "species_29420" ], "modifiers": [ [ "species_10755584", "catalyst" ] ], "additional_components": [ "species_29420", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "species_29438", "Q9Y7Q7", "SPCC297.05" ] }, "reaction_10755519": { "compartment": "compartment_263163", "id": "reaction_10755519", "reactome": "R-SPO-8876190", "name": "RAB8 GEFs exchange GTP for GDP on RAB8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755502" ], "products": [ "species_10755437", "species_10755514", "species_29420" ], "modifiers": [ [ "species_10755516", "catalyst" ] ], "additional_components": [ "species_29420", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "species_29438", "O13930", "SPAC23C4.10", "C6Y4C9", "SPCC1183.12" ] }, "reaction_10752787": { "compartment": "compartment_6791047", "id": "reaction_10752787", "reactome": "R-SPO-6807872", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752741", "species_10752783" ], "products": [ "species_10752785" ], "modifiers": [], "additional_components": [ "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "O42937", "SPBC16C6.13c", "O13690", "SPBC211.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "Q09857", "SPAC29E6.03c" ] }, "reaction_10754708": { "compartment": "compartment_70101", "id": "reaction_10754708", "reactome": "R-SPO-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754684", "species_10754704" ], "products": [ "species_10754706" ], "modifiers": [], "additional_components": [ "Q10169", "SPBC3B8.05", "O42967", "SPBC1E8.02", "Q9USZ7", "SPBC11G11.02c", "O74423", "SPCC162.07", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "P78813", "SPCC794.11c", "O94685", "SPBC83.01", "Q9USZ7", "SPBC11G11.02c", "Q10169", "SPBC3B8.05", "O74423", "SPCC162.07", "Q9HGL2", "SPBC800.10c", "O42967", "SPBC1E8.02", "Q10172", "SPAC25G10.09c", "P78813", "SPCC794.11c", "O94685", "SPBC83.01" ] }, "reaction_10735482": { "compartment": "compartment_7660", "id": "reaction_10735482", "reactome": "R-SPO-174110", "name": "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10735478" ], "products": [ "species_113550", "species_10735480" ], "modifiers": [ [ "species_10729577", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "SPAC24H6.05" ] }, "reaction_10729374": { "compartment": "compartment_7660", "id": "reaction_10729374", "reactome": "R-SPO-68950", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_30187", "species_29604", "species_29892", "species_10728770" ], "products": [ "species_10729371" ], "modifiers": [ [ "species_10728742", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c" ] }, "reaction_10733290": { "compartment": "compartment_70101", "id": "reaction_10733290", "reactome": "R-SPO-75825", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733288" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P10815", "SPBC582.03", "P0C8R3", "SPAC589.10c", "P25009", "SPBC19F5.01c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10735822": { "compartment": "compartment_7660", "id": "reaction_10735822", "reactome": "R-SPO-187948", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10735523" ], "products": [ "species_113582", "species_10735525" ], "modifiers": [ [ "species_10728937", "catalyst" ] ], "additional_components": [ "SPAC144.13c", "SPAC144.13c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10735825": { "compartment": "compartment_7660", "id": "reaction_10735825", "reactome": "R-SPO-187949", "name": "CAK-mediated phosphorylation of Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10735480" ], "products": [ "species_113582", "species_10728937" ], "modifiers": [ [ "species_10732457", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07" ] }, "reaction_10728773": { "compartment": "compartment_7660", "id": "reaction_10728773", "reactome": "R-SPO-68913", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10728768" ], "products": [ "species_10728764", "species_10728770" ], "modifiers": [ [ "species_10728768", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10733284": { "compartment": "compartment_13231", "id": "reaction_10733284", "reactome": "R-SPO-75822", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733270" ], "products": [ "species_10733282" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10733286": { "compartment": "compartment_13231", "id": "reaction_10733286", "reactome": "R-SPO-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733266" ], "products": [ "species_10733278" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c" ] }, "reaction_10735527": { "compartment": "compartment_13231", "id": "reaction_10735527", "reactome": "R-SPO-174273", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735466" ], "products": [ "species_10735480" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10735468": { "compartment": "compartment_70101", "id": "reaction_10735468", "reactome": "R-SPO-174054", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735434", "species_10729541" ], "products": [ "species_10735466" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "SPBC11B10.09", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10740250": { "compartment": "compartment_70101", "id": "reaction_10740250", "reactome": "R-SPO-549192", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76103", "species_75967" ], "products": [ "species_76194", "species_549167" ], "modifiers": [ [ "species_10740247", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10733412": { "compartment": "compartment_70101", "id": "reaction_10733412", "reactome": "R-SPO-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76108" ], "products": [ "species_76103", "species_29372" ], "modifiers": [ [ "species_10733405", "catalyst" ] ], "additional_components": [ "SPAC1952.13" ] }, "reaction_10752220": { "compartment": "compartment_12045", "id": "reaction_10752220", "reactome": "R-SPO-6800334", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6800352", "species_1500578" ], "products": [ "species_76194", "species_76103" ], "modifiers": [ [ "species_10752213", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10735159": { "compartment": "compartment_70101", "id": "reaction_10735159", "reactome": "R-SPO-165162", "name": "Phosphorylation of TSC2 by PKB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735151" ], "products": [ "species_29370", "species_10735156" ], "modifiers": [ [ "species_10733746", "catalyst" ] ], "additional_components": [ "SPAC630.13c", "SPAC630.13c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c" ] }, "reaction_10735185": { "compartment": "compartment_17938", "id": "reaction_10735185", "reactome": "R-SPO-165195", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10735181" ], "products": [ "species_29420", "species_10735183" ], "modifiers": [], "additional_components": [ "species_29420", "O94363", "SPBC428.16c", "species_29438", "O94363", "SPBC428.16c" ] }, "reaction_10738133": { "compartment": "compartment_70101", "id": "reaction_10738133", "reactome": "R-SPO-380930", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736802", "species_76577" ], "products": [ "species_10738128" ], "modifiers": [], "additional_components": [ "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10735204": { "compartment": "compartment_70101", "id": "reaction_10735204", "reactome": "R-SPO-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731629", "species_113592" ], "products": [ "species_29370", "species_10735201" ], "modifiers": [ [ "species_10735194", "catalyst" ] ], "additional_components": [ "SPAPB1E7.12", "SPAPB1E7.12", "SPCC4G3.08" ] }, "reaction_10757820": { "compartment": "compartment_70101", "id": "reaction_10757820", "reactome": "R-SPO-9679044", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757816", "species_9678687" ], "products": [ "species_10757818" ], "modifiers": [], "additional_components": [ "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c", "species_9678687", "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c" ] }, "reaction_10738131": { "compartment": "compartment_70101", "id": "reaction_10738131", "reactome": "R-SPO-380927", "name": "p-AMPK phosphorylates TSC1:TSC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735168" ], "products": [ "species_29370", "species_10738126" ], "modifiers": [ [ "species_10738128", "catalyst" ] ], "additional_components": [ "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10735211": { "compartment": "compartment_70101", "id": "reaction_10735211", "reactome": "R-SPO-165766", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10731799" ], "products": [ "species_29370", "species_10735209" ], "modifiers": [ [ "species_10735194", "catalyst" ] ], "additional_components": [ "SPAC17C9.03", "SPAC17C9.03", "SPCC4G3.08" ] }, "reaction_10735174": { "compartment": "compartment_70101", "id": "reaction_10735174", "reactome": "R-SPO-165182", "name": "Phosphorylation of complexed TSC2 by PKB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735168" ], "products": [ "species_29370", "species_10735172" ], "modifiers": [ [ "species_10733746", "catalyst" ] ], "additional_components": [ "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c" ] }, "reaction_10746540": { "compartment": "compartment_70101", "id": "reaction_10746540", "reactome": "R-SPO-5653957", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746523", "species_10746536" ], "products": [ "species_10746538" ], "modifiers": [], "additional_components": [ "O74824", "SPBC337.13c", "species_29438", "species_29420", "O74544", "SPCC777.05", "species_29420", "O74544", "SPCC777.05", "O74824", "SPBC337.13c", "species_29438" ] }, "reaction_10741434": { "compartment": "compartment_70101", "id": "reaction_10741434", "reactome": "R-SPO-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741400" ], "products": [ "species_10741402" ], "modifiers": [], "additional_components": [ "SPAC25G10.07c", "P24339", "SPAC25G10.07c" ] }, "reaction_10753183": { "compartment": "compartment_17951", "id": "reaction_10753183", "reactome": "R-SPO-6810076", "name": "DDO oxidizes D-Asp to OA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810061", "species_141343", "species_113535" ], "products": [ "species_389843", "species_6810070", "species_113575" ], "modifiers": [ [ "species_10753180", "catalyst" ] ], "additional_components": [ "Q9Y7N4", "SPCC1450.07c", "species_113596" ] }, "reaction_10749687": { "compartment": "compartment_5460", "id": "reaction_10749687", "reactome": "R-SPO-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10749674" ], "products": [ "species_29362", "species_113529", "species_10749657" ], "modifiers": [ [ "species_10749684", "catalyst" ] ], "additional_components": [ "CHEBI:50746", "Q9HDV9", "SPBP19A11.01", "SPBP19A11.01", "O00087", "SPAC1002.09c", "species_113596" ] }, "reaction_10749682": { "compartment": "compartment_5460", "id": "reaction_10749682", "reactome": "R-SPO-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749661", "species_200671" ], "products": [ "species_5693984", "species_10749674", "species_5693978" ], "modifiers": [ [ "species_10749679", "catalyst" ] ], "additional_components": [ "CHEBI:14949", "Q9HDV9", "SPBP19A11.01", "CHEBI:50746", "Q9HDV9", "SPBP19A11.01", "SPAC31G5.14" ] }, "reaction_10750347": { "compartment": "compartment_5460", "id": "reaction_10750347", "reactome": "R-SPO-6784224", "name": "PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215" ], "products": [ "species_6784241" ], "modifiers": [ [ "species_10750344", "catalyst" ] ], "additional_components": [ "O74524", "SPCC70.03c", "species_113596" ] }, "reaction_10738379": { "compartment": "compartment_17951", "id": "reaction_10738379", "reactome": "R-SPO-389842", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389822", "species_113535" ], "products": [ "species_389678", "species_113575" ], "modifiers": [ [ "species_10738376", "catalyst" ] ], "additional_components": [ "species_73524", "Q9HDX2", "SPAPB1A11.03" ] }, "reaction_10738367": { "compartment": "compartment_17951", "id": "reaction_10738367", "reactome": "R-SPO-389821", "name": "glycine + O2 => glyoxylate + H2O2 + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193446", "species_141343", "species_113535" ], "products": [ "species_389678", "species_389843", "species_113575" ], "modifiers": [ [ "species_10738364", "catalyst" ] ], "additional_components": [ "Q9Y7N4", "SPCC1450.07c", "species_113596" ] }, "reaction_10751187": { "compartment": "compartment_5460", "id": "reaction_10751187", "reactome": "R-SPO-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6793610", "species_2162265", "species_10751177" ], "products": [ "species_6793613", "species_379705", "species_10749657" ], "modifiers": [ [ "species_10751184", "catalyst" ] ], "additional_components": [ "SPBP19A11.01", "SPBP19A11.01", "O13642", "SPBC8D2.15", "CHEBI:49883" ] }, "reaction_10749672": { "compartment": "compartment_5460", "id": "reaction_10749672", "reactome": "R-SPO-5693967", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_10749657" ], "products": [ "species_10749661", "species_29376" ], "modifiers": [ [ "species_10749669", "catalyst" ] ], "additional_components": [ "SPBP19A11.01", "CHEBI:14949", "Q9HDV9", "SPBP19A11.01", "Q09785", "SPAC13G6.06c" ] }, "reaction_10750350": { "compartment": "compartment_5460", "id": "reaction_10750350", "reactome": "R-SPO-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_6784236" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10729968", "catalyst" ] ], "additional_components": [ "O94320", "SPBC725.01" ] }, "reaction_10738382": { "compartment": "compartment_17951", "id": "reaction_10738382", "reactome": "R-SPO-389862", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389678", "species_141343", "species_113535" ], "products": [ "species_389819", "species_113575" ], "modifiers": [ [ "species_10738376", "catalyst" ] ], "additional_components": [ "species_73524", "Q9HDX2", "SPAPB1A11.03" ] }, "reaction_10751156": { "compartment": "compartment_5460", "id": "reaction_10751156", "reactome": "R-SPO-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751146", "species_10749657" ], "products": [ "species_10749659", "species_10751148" ], "modifiers": [ [ "species_10751153", "catalyst" ] ], "additional_components": [ "O94681", "SPBC776.15c", "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "CHEBI:17460", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "O74378", "SPBC3H7.03c", "species_113596", "SPBP19A11.01", "SPBP19A11.01", "O94681", "SPBC776.15c", "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "CHEBI:17460", "O74378", "SPBC3H7.03c", "species_113596", "SPBC17A3.09c" ] }, "reaction_10749950": { "compartment": "compartment_5460", "id": "reaction_10749950", "reactome": "R-SPO-5696408", "name": "PXLP-K278-PHYKPL tetramer hydrolyses 5PHL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_5696409" ], "products": [ "species_113556", "species_113548", "species_5693978" ], "modifiers": [ [ "species_10749947", "catalyst" ] ], "additional_components": [ "Q9US34", "SPAC1039.07c" ] }, "reaction_10737977": { "compartment": "compartment_70101", "id": "reaction_10737977", "reactome": "R-SPO-351948", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737973" ], "products": [ "species_10737975" ], "modifiers": [ [ "species_10737921", "catalyst" ] ], "additional_components": [ "SPAC767.01c", "SPAC767.01c", "SPAC9E9.04" ] }, "reaction_10754771": { "compartment": "compartment_70616", "id": "reaction_10754771", "reactome": "R-SPO-8867344", "name": "OMA1 hydrolyses OPA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754747", "species_113521" ], "products": [ "species_10754763", "species_10754755" ], "modifiers": [ [ "species_10754768", "catalyst" ] ], "additional_components": [ "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "SPAP14E8.04" ] }, "reaction_10747046": { "compartment": "compartment_70101", "id": "reaction_10747046", "reactome": "R-SPO-5675470", "name": "BIRC2/3 (cIAP1/2) is autoubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737150", "species_10747036" ], "products": [ "species_10747039" ], "modifiers": [ [ "species_10737150", "catalyst" ] ], "additional_components": [ "SPCC962.02c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPCC962.02c", "SPCC962.02c" ] }, "reaction_10752633": { "compartment": "compartment_70101", "id": "reaction_10752633", "reactome": "R-SPO-6805811", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752617" ], "products": [ "species_10752631" ], "modifiers": [], "additional_components": [ "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11", "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11" ] }, "reaction_10737755": { "compartment": "compartment_7660", "id": "reaction_10737755", "reactome": "R-SPO-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737751", "species_29428" ], "products": [ "species_10737753" ], "modifiers": [], "additional_components": [ "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c", "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c" ] }, "reaction_10737971": { "compartment": "compartment_13231", "id": "reaction_10737971", "reactome": "R-SPO-351947", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737945" ], "products": [ "species_10737969" ], "modifiers": [], "additional_components": [ "Q10447", "SPAC12B10.14c", "O75011", "SPBC17F3.02", "O14047", "SPAC2C4.14c", "O14305", "SPAC9G1.09", "Q10447", "SPAC12B10.14c", "O75011", "SPBC17F3.02", "O14047", "SPAC2C4.14c", "O14305", "SPAC9G1.09" ] }, "reaction_10757583": { "compartment": "compartment_70101", "id": "reaction_10757583", "reactome": "R-SPO-9641096", "name": "Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757575", "species_10757579" ], "products": [ "species_10757581" ], "modifiers": [], "additional_components": [ "SPAC22E12.03c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10757601": { "compartment": "compartment_70101", "id": "reaction_10757601", "reactome": "R-SPO-9641111", "name": "Parkin transfers Ub to misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757581" ], "products": [ "species_10757599" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10757649": { "compartment": "compartment_18667", "id": "reaction_10757649", "reactome": "R-SPO-9646685", "name": "Aggresome dissociates from dynein and microtubule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757641" ], "products": [ "species_10757647", "species_10738115", "species_10757627" ], "modifiers": [], "additional_components": [ "P04689", "SPBC800.05c", "Q92337", "SPAC9E9.12c", "Q9P3W4", "SPAC458.04c", "Q10356", "SPAC22E12.03c", "P05219", "SPBC26H8.07c", "species_29438", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c", "species_29420", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9P7V2", "SPAC30.04c", "P04688", "SPBC16A3.15c", "O13290", "SPAC1093.06c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04", "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "Q9P3W4", "SPAC458.04c", "O13290", "SPAC1093.06c", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c" ] }, "reaction_10757603": { "compartment": "compartment_70101", "id": "reaction_10757603", "reactome": "R-SPO-9641127", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757599" ], "products": [ "species_10757592" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10757631": { "compartment": "compartment_70101", "id": "reaction_10757631", "reactome": "R-SPO-9646348", "name": "PolyUb-Misfolded Proteins:HDAC6 bind dynein motor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757610", "species_10757627" ], "products": [ "species_10757629" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04", "Q9P3W4", "SPAC458.04c", "O13290", "SPAC1093.06c", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "Q9P3W4", "SPAC458.04c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O13290", "SPAC1093.06c", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04" ] }, "reaction_10730221": { "compartment": "compartment_70101", "id": "reaction_10730221", "reactome": "R-SPO-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10730218", "catalyst" ] ], "additional_components": [ "O42658", "SPAC27D7.04" ] }, "reaction_10740374": { "compartment": "compartment_70101", "id": "reaction_10740374", "reactome": "R-SPO-893593", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29502", "species_29398" ], "products": [ "species_893599", "species_29432" ], "modifiers": [ [ "species_10740371", "catalyst" ] ], "additional_components": [ "O14209", "SPAC6B12.04c" ] }, "reaction_10747288": { "compartment": "compartment_5683628", "id": "reaction_10747288", "reactome": "R-SPO-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747126" ], "products": [ "species_10747279" ], "modifiers": [ [ "species_10740430", "catalyst" ], [ "species_10747286", "catalyst" ] ], "additional_components": [ "O94272", "SPBP8B7.24c", "species_1500581", "O94272", "SPBP8B7.24c", "species_1500581", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O60149", "SPBC18H10.19", "P87117", "SPAC20G8.10c" ] }, "reaction_10747194": { "compartment": "compartment_70101", "id": "reaction_10747194", "reactome": "R-SPO-5681981", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747189" ], "products": [ "species_10747191" ], "modifiers": [ [ "species_10747189", "catalyst" ] ], "additional_components": [ "O43035", "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c", "O43069", "SPBC6B1.05c", "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "O43035", "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c" ] }, "reaction_10746800": { "compartment": "compartment_70101", "id": "reaction_10746800", "reactome": "R-SPO-5672008", "name": "Thr-180 of ULK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746707" ], "products": [ "species_29370", "species_10746797" ], "modifiers": [ [ "species_10746707", "catalyst" ] ], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10757752": { "compartment": "compartment_17947", "id": "reaction_10757752", "reactome": "R-SPO-9664888", "name": "ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757718" ], "products": [ "species_10757740" ], "modifiers": [], "additional_components": [ "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10747085": { "compartment": "compartment_70101", "id": "reaction_10747085", "reactome": "R-SPO-5676229", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747081", "species_5693050" ], "products": [ "species_10747083" ], "modifiers": [], "additional_components": [ "Q9P6N1", "SPAC823.16c", "Q9HDZ7", "SPAC589.07c", "Q9P3W2", "SPAC458.06", "Q9P6N1", "SPAC823.16c", "Q9HDZ7", "SPAC589.07c", "Q9P3W2", "SPAC458.06", "species_1629751" ] }, "reaction_10756472": { "compartment": "compartment_21994", "id": "reaction_10756472", "reactome": "R-SPO-8959571", "name": "LC3 binds the autophagosome membrane Atg5-Atg12 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745146", "species_10756468" ], "products": [ "species_10756470" ], "modifiers": [], "additional_components": [ "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c", "O94272", "SPBP8B7.24c", "O14020", "SPAC29A4.17c", "O94272", "SPBP8B7.24c", "Q9US24", "SPAC1783.06c", "O14020", "SPAC29A4.17c", "O74971", "SPBC4B4.10c" ] }, "reaction_10747385": { "compartment": "compartment_70101", "id": "reaction_10747385", "reactome": "R-SPO-5682690", "name": "ATG10 dissociates from ATG12:ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747383" ], "products": [ "species_10747381", "species_10747137" ], "modifiers": [], "additional_components": [ "Q9US24", "SPAC1783.06c", "Q9UTD5", "SPAC227.04", "O74971", "SPBC4B4.10c", "SPAC227.04", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c" ] }, "reaction_10756095": { "compartment": "compartment_70101", "id": "reaction_10756095", "reactome": "R-SPO-8948039", "name": "FUNDC1 is phosphorylated by CK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756090", "species_113592" ], "products": [ "species_29370", "species_10756093" ], "modifiers": [ [ "species_10743403", "catalyst" ] ], "additional_components": [ "SPAC29A4.17c", "SPAC29A4.17c", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11" ] }, "reaction_10746802": { "compartment": "compartment_70101", "id": "reaction_10746802", "reactome": "R-SPO-5672011", "name": "p-AMPK:AMP binds the ULK complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746699", "species_10738128" ], "products": [ "species_10746701" ], "modifiers": [], "additional_components": [ "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O36019", "SPAC4F10.07c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O74536", "SPCC74.03c", "O36019", "SPAC4F10.07c", "P78789", "SPCC1919.03c" ] }, "reaction_10747172": { "compartment": "compartment_70101", "id": "reaction_10747172", "reactome": "R-SPO-5679239", "name": "ULK complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747055" ], "products": [ "species_10742300" ], "modifiers": [], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "Q9Y7T4", "SPCC63.08c", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10747484": { "compartment": "compartment_70101", "id": "reaction_10747484", "reactome": "R-SPO-5683588", "name": "ATG10 transfers ATG12 from ATG10 to ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747214" ], "products": [ "species_10747383" ], "modifiers": [], "additional_components": [ "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c", "Q9US24", "SPAC1783.06c", "Q9UTD5", "SPAC227.04", "O74971", "SPBC4B4.10c" ] }, "reaction_10747216": { "compartment": "compartment_70101", "id": "reaction_10747216", "reactome": "R-SPO-5682010", "name": "ATG10:ATG12 binds ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747210", "species_10747212" ], "products": [ "species_10747214" ], "modifiers": [], "additional_components": [ "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c", "SPBC4B4.10c", "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c" ] }, "reaction_10757705": { "compartment": "compartment_70101", "id": "reaction_10757705", "reactome": "R-SPO-9664850", "name": "ATM binds PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757061", "species_10757701" ], "products": [ "species_10757703" ], "modifiers": [], "additional_components": [ "SPBC725.07", "SPCC23B6.03c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10747180": { "compartment": "compartment_70101", "id": "reaction_10747180", "reactome": "R-SPO-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747176", "species_10747132" ], "products": [ "species_10747178" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "SPAC1783.06c", "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c" ] }, "reaction_10756108": { "compartment": "compartment_17906", "id": "reaction_10756108", "reactome": "R-SPO-8948146", "name": "FUNDC1 is phosphorylated by ULK1 at Ser17", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756090", "species_113592" ], "products": [ "species_29370", "species_10756105" ], "modifiers": [ [ "species_10756097", "catalyst" ] ], "additional_components": [ "SPAC29A4.17c", "SPAC29A4.17c", "SPCC63.08c" ] }, "reaction_10746710": { "compartment": "compartment_70101", "id": "reaction_10746710", "reactome": "R-SPO-5665868", "name": "AMPK (complex) phosphorylates ULK1 (complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746701", "species_113592" ], "products": [ "species_29370", "species_10746707" ], "modifiers": [ [ "species_10746701", "catalyst" ] ], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O74536", "SPCC74.03c", "O36019", "SPAC4F10.07c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O74536", "SPCC74.03c", "O36019", "SPAC4F10.07c", "P78789", "SPCC1919.03c" ] }, "reaction_10757750": { "compartment": "compartment_70101", "id": "reaction_10757750", "reactome": "R-SPO-9664883", "name": "ATM:PEX5 translocates from cytosol to peroxisomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757703" ], "products": [ "species_10757709" ], "modifiers": [], "additional_components": [ "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10757720": { "compartment": "compartment_17947", "id": "reaction_10757720", "reactome": "R-SPO-9664862", "name": "ATM dimer:PEX5 phosphorylates PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757711" ], "products": [ "species_10757718" ], "modifiers": [], "additional_components": [ "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10747174": { "compartment": "compartment_70101", "id": "reaction_10747174", "reactome": "R-SPO-5679266", "name": "Beclin-1 complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742261" ], "products": [ "species_10747165" ], "modifiers": [], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O42862", "SPAC25A8.02", "P87117", "SPAC20G8.10c" ] }, "reaction_10747146": { "compartment": "compartment_70101", "id": "reaction_10747146", "reactome": "R-SPO-5678490", "name": "ATG16L1 complex transfers LC3 from ATG3 to PE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747124", "species_5681998" ], "products": [ "species_10747128", "species_10747126" ], "modifiers": [ [ "species_10747143", "catalyst" ] ], "additional_components": [ "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "species_1500581", "species_6809774", "Q9HDZ7", "SPAC589.07c", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c" ] }, "reaction_10756099": { "compartment": "compartment_17906", "id": "reaction_10756099", "reactome": "R-SPO-8948136", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746691" ], "products": [ "species_10756097" ], "modifiers": [], "additional_components": [ "SPCC63.08c", "SPCC63.08c" ] }, "reaction_10747268": { "compartment": "compartment_12045", "id": "reaction_10747268", "reactome": "R-SPO-5682385", "name": "The phagophore extends from the PIP3-enriched structure", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746809" ], "products": [ "species_10747259" ], "modifiers": [ [ "species_10747264", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O42862", "SPAC25A8.02", "P87117", "SPAC20G8.10c", "SPBC15D4.07c" ] }, "reaction_10747170": { "compartment": "compartment_70101", "id": "reaction_10747170", "reactome": "R-SPO-5679206", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030" ], "products": [ "species_426639" ], "modifiers": [ [ "species_10742434", "catalyst" ] ], "additional_components": [ "SPAC19A8.03" ] }, "reaction_10747218": { "compartment": "compartment_70101", "id": "reaction_10747218", "reactome": "R-SPO-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747110", "species_10747176" ], "products": [ "species_10747187" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "O43069", "SPBC6B1.05c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c" ] }, "reaction_10747486": { "compartment": "compartment_70101", "id": "reaction_10747486", "reactome": "R-SPO-5683593", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747191" ], "products": [ "species_10747176", "species_10747124" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "O43069", "SPBC6B1.05c", "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c" ] }, "reaction_10757748": { "compartment": "compartment_17947", "id": "reaction_10757748", "reactome": "R-SPO-9664880", "name": "MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747112", "species_10757744" ], "products": [ "species_10757746" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "Q9P792", "SPBP35G2.11c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "Q9P792", "SPBP35G2.11c", "O94272", "SPBP8B7.24c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10756474": { "compartment": "compartment_70101", "id": "reaction_10756474", "reactome": "R-SPO-8959573", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747110", "species_10756105" ], "products": [ "species_10756468" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "SPAC29A4.17c", "O94272", "SPBP8B7.24c", "O14020", "SPAC29A4.17c" ] }, "reaction_10747167": { "compartment": "compartment_70101", "id": "reaction_10747167", "reactome": "R-SPO-5679205", "name": "ULK1 phosphorylates Beclin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10747165" ], "products": [ "species_29370", "species_10746809" ], "modifiers": [ [ "species_10742300", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O42862", "SPAC25A8.02", "P87117", "SPAC20G8.10c", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10747524": { "compartment": "compartment_70101", "id": "reaction_10747524", "reactome": "R-SPO-5683925", "name": "ULK1 is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747522" ], "products": [ "species_10746699", "species_29372" ], "modifiers": [], "additional_components": [ "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O36019", "SPAC4F10.07c" ] }, "reaction_10747431": { "compartment": "compartment_70101", "id": "reaction_10747431", "reactome": "R-SPO-5682896", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747128", "species_10747187" ], "products": [ "species_10747189" ], "modifiers": [], "additional_components": [ "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c", "O43035", "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c" ] }, "reaction_10757731": { "compartment": "compartment_17947", "id": "reaction_10757731", "reactome": "R-SPO-9664879", "name": "ATM:PEX5 binds ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757707", "species_10757709" ], "products": [ "species_10757711" ], "modifiers": [ [ "species_1250243", "catalyst" ] ], "additional_components": [ "SPCC23B6.03c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10746812": { "compartment": "compartment_12045", "id": "reaction_10746812", "reactome": "R-SPO-5672012", "name": "Beclin-1 complex phosphorylates PtdIns", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_5676030", "species_29370" ], "modifiers": [ [ "species_10746809", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02" ] }, "reaction_10747429": { "compartment": "compartment_70101", "id": "reaction_10747429", "reactome": "R-SPO-5682893", "name": "ATG12:ATG7:CysO572-ATG7 binds ATG10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747425", "species_10747381" ], "products": [ "species_10747427" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c", "SPAC227.04", "O43069", "SPBC6B1.05c", "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c" ] }, "reaction_10742303": { "compartment": "compartment_70101", "id": "reaction_10742303", "reactome": "R-SPO-1632857", "name": "ULK1 phosphorylates AMBRA1:BECN1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742263", "species_113592" ], "products": [ "species_10742269", "species_29370" ], "modifiers": [ [ "species_10742300", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "Q9UR05", "SPAC926.07c", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "Q9UR05", "SPAC926.07c", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10747058": { "compartment": "compartment_70101", "id": "reaction_10747058", "reactome": "R-SPO-5675868", "name": "ULK1 phosphorylates ATG13 and RB1CC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746797", "species_113592" ], "products": [ "species_29370", "species_10747055" ], "modifiers": [ [ "species_10746797", "catalyst" ] ], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "Q9Y7T4", "SPCC63.08c", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10757729": { "compartment": "compartment_17947", "id": "reaction_10757729", "reactome": "R-SPO-9664867", "name": "NBR1 binds MAP1LC3B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747112", "species_10757725" ], "products": [ "species_10757727" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "SPBP35G2.11c", "Q9P792", "SPBP35G2.11c", "O94272", "SPBP8B7.24c" ] }, "reaction_10756986": { "compartment": "compartment_70101", "id": "reaction_10756986", "reactome": "R-SPO-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747178" ], "products": [ "species_10747425" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c", "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c" ] }, "reaction_10733817": { "compartment": "compartment_70101", "id": "reaction_10733817", "reactome": "R-SPO-109864", "name": "Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733810" ], "products": [ "species_10733776", "species_10733808" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "SPAC1D4.13", "SPAC31G5.09c" ] }, "reaction_10757664": { "compartment": "compartment_876", "id": "reaction_10757664", "reactome": "R-SPO-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10737221" ], "products": [ "species_10757662" ], "modifiers": [], "additional_components": [ "O42881", "SPAC8E11.04c", "species_9647934", "O42881", "SPAC8E11.04c" ] }, "reaction_10746851": { "compartment": "compartment_20699", "id": "reaction_10746851", "reactome": "R-SPO-5674373", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746846" ], "products": [ "species_29370", "species_10746848" ], "modifiers": [ [ "species_10746846", "catalyst" ] ], "additional_components": [ "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10733772": { "compartment": "compartment_70101", "id": "reaction_10733772", "reactome": "R-SPO-109857", "name": "MAP2K1 binds MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733756", "species_10733768" ], "products": [ "species_10733770" ], "modifiers": [], "additional_components": [ "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08" ] }, "reaction_10757671": { "compartment": "compartment_12045", "id": "reaction_10757671", "reactome": "R-SPO-9653514", "name": "USP17L2 deubiquitinates RCE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757666", "species_29356" ], "products": [ "species_10757668", "species_10749260" ], "modifiers": [ [ "species_10749999", "catalyst" ] ], "additional_components": [ "SPAC1687.02", "SPAC1687.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPCC1682.12c" ] }, "reaction_10746325": { "compartment": "compartment_70101", "id": "reaction_10746325", "reactome": "R-SPO-5627775", "name": "Autophosphorylation of PAK1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746306" ], "products": [ "species_29370", "species_10746322", "species_10738231" ], "modifiers": [ [ "species_10746306", "catalyst" ] ], "additional_components": [ "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c" ] }, "reaction_10757660": { "compartment": "compartment_70101", "id": "reaction_10757660", "reactome": "R-SPO-9647987", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9653479", "species_10757656" ], "products": [ "species_10757658" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "LigandDisplayForward?ligandId=8030", "O13782", "SPAC17G6.04c", "O60052", "SPAPB1A10.04c", "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "O13782", "SPAC17G6.04c", "O60052", "SPAPB1A10.04c", "LigandDisplayForward?ligandId=8030" ] }, "reaction_10746861": { "compartment": "compartment_7660", "id": "reaction_10746861", "reactome": "R-SPO-5674387", "name": "Phosphorylated MAPKs translocate into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746855" ], "products": [ "species_10746859" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10733782": { "compartment": "compartment_70101", "id": "reaction_10733782", "reactome": "R-SPO-109858", "name": "MAP2K2 binds MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733778", "species_10733776" ], "products": [ "species_10733780" ], "modifiers": [], "additional_components": [ "SPAC31G5.09c", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13" ] }, "reaction_10733815": { "compartment": "compartment_70101", "id": "reaction_10733815", "reactome": "R-SPO-109863", "name": "Dissociation of p-T,Y-MAPK3:MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733794" ], "products": [ "species_10733792", "species_10733756" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPAC1D4.13" ] }, "reaction_10754546": { "compartment": "compartment_7660", "id": "reaction_10754546", "reactome": "R-SPO-8856945", "name": "PP2A methylation by LCMT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754531", "species_77087" ], "products": [ "species_10754538", "species_77502" ], "modifiers": [ [ "species_10754543", "catalyst" ] ], "additional_components": [ "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "SPBP8B7.08c" ] }, "reaction_10735452": { "compartment": "compartment_13231", "id": "reaction_10735452", "reactome": "R-SPO-170159", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735448" ], "products": [ "species_10735450" ], "modifiers": [], "additional_components": [ "P06652", "SPAC24H6.05", "P06652", "SPAC24H6.05" ] }, "reaction_10754554": { "compartment": "compartment_7660", "id": "reaction_10754554", "reactome": "R-SPO-8856951", "name": "PP2A demethylation by PPME1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10754538" ], "products": [ "species_8857797", "species_10754531" ], "modifiers": [ [ "species_10754551", "catalyst" ] ], "additional_components": [ "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "SPBP4H10.17c" ] }, "reaction_10734633": { "compartment": "compartment_7660", "id": "reaction_10734633", "reactome": "R-SPO-156678", "name": "Activation of Cdc25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734625" ], "products": [ "species_29370", "species_10734628" ], "modifiers": [ [ "species_10734630", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC23C11.16" ] }, "reaction_10735444": { "compartment": "compartment_13231", "id": "reaction_10735444", "reactome": "R-SPO-170149", "name": "Translocation of active Cdc25C to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734628" ], "products": [ "species_10735442" ], "modifiers": [], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05" ] }, "reaction_10735440": { "compartment": "compartment_13231", "id": "reaction_10735440", "reactome": "R-SPO-170120", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735436" ], "products": [ "species_10735438" ], "modifiers": [], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05" ] }, "reaction_10743753": { "compartment": "compartment_70101", "id": "reaction_10743753", "reactome": "R-SPO-3002798", "name": "Cytosolic PLK1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734630" ], "products": [ "species_10734620" ], "modifiers": [], "additional_components": [ "SPAC23C11.16", "SPAC23C11.16" ] }, "reaction_10734775": { "compartment": "compartment_7660", "id": "reaction_10734775", "reactome": "R-SPO-162657", "name": "Inactivation of Myt1 kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10734770" ], "products": [ "species_113582", "species_10734773" ], "modifiers": [ [ "species_10734620", "catalyst" ] ], "additional_components": [ "SPAC23C11.16" ] }, "reaction_10743650": { "compartment": "compartment_7660", "id": "reaction_10743650", "reactome": "R-SPO-2993780", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743639", "species_10743587" ], "products": [ "species_10743647", "species_10743572" ], "modifiers": [ [ "species_10743572", "catalyst" ] ], "additional_components": [ "SPAC30D11.13", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04" ] }, "reaction_10743604": { "compartment": "compartment_7660", "id": "reaction_10743604", "reactome": "R-SPO-2990840", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743592" ], "products": [ "species_10743577" ], "modifiers": [ [ "species_10743597", "catalyst" ] ], "additional_components": [ "SPBC365.06", "SPBC365.06", "SPBC19G7.09" ] }, "reaction_10743590": { "compartment": "compartment_7660", "id": "reaction_10743590", "reactome": "R-SPO-2990833", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10743577", "species_10743572" ], "products": [ "species_10743587", "species_164121", "species_113541" ], "modifiers": [ [ "species_10743572", "catalyst" ] ], "additional_components": [ "SPBC365.06", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O13351", "SPBC365.06", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04" ] }, "reaction_10749697": { "compartment": "compartment_70101", "id": "reaction_10749697", "reactome": "R-SPO-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5694074" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10749694", "catalyst" ] ], "additional_components": [ "species_442320", "Q09751", "SPBC12C2.12c" ] }, "reaction_10739914": { "compartment": "compartment_5460", "id": "reaction_10739914", "reactome": "R-SPO-450975", "name": "isocitrate <=> citrate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938" ], "products": [ "species_29654" ], "modifiers": [ [ "species_10730103", "catalyst" ] ], "additional_components": [ "SPAC24C9.06c" ] }, "reaction_10737284": { "compartment": "compartment_5460", "id": "reaction_10737284", "reactome": "R-SPO-203946", "name": "PDK isoforms phosphorylate lipo-PDH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_10730323" ], "products": [ "species_10737268", "species_113581" ], "modifiers": [ [ "species_10737273", "catalyst" ], [ "species_113559", "catalyst" ], [ "species_29362", "catalyst" ], [ "species_113557", "inhibitor" ], [ "species_10737282", "inhibitor" ] ], "additional_components": [ "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "species_113596", "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "species_113596", "SPAC644.11c", "species_9010792", "Q9P6P9", "SPAC644.11c" ] }, "reaction_10730326": { "compartment": "compartment_5460", "id": "reaction_10730326", "reactome": "R-SPO-71397", "name": "lipo-PDH decarboxylates PYR to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113557", "species_113526" ], "products": [ "species_29376", "species_29362", "species_113559" ], "modifiers": [ [ "species_10730323", "catalyst" ] ], "additional_components": [ "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "species_113596" ] }, "reaction_10756610": { "compartment": "compartment_5460", "id": "reaction_10756610", "reactome": "R-SPO-9011543", "name": "DCA binds PDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9010792", "species_10737275" ], "products": [ "species_10737282" ], "modifiers": [], "additional_components": [ "SPAC644.11c", "species_9010792", "Q9P6P9", "SPAC644.11c" ] }, "reaction_10735422": { "compartment": "compartment_5460", "id": "reaction_10735422", "reactome": "R-SPO-169270", "name": "ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_10735411" ], "products": [ "species_76633", "species_10735409" ], "modifiers": [ [ "species_10735419", "catalyst" ] ], "additional_components": [ "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_31649", "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_113596", "SPAC20G8.04c" ] }, "reaction_10730165": { "compartment": "compartment_5460", "id": "reaction_10730165", "reactome": "R-SPO-70994", "name": "Succinate <=> Fumarate (with FAD redox reaction on enzyme)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113536" ], "products": [ "species_113588" ], "modifiers": [ [ "species_10730162", "catalyst" ] ], "additional_components": [ "Q9P7X0", "SPBP23A10.16", "Q9UTJ7", "SPAC1556.02c", "O74882", "SPCC330.12c", "P21911", "SPAC140.01", "species_113596" ] }, "reaction_10730116": { "compartment": "compartment_5460", "id": "reaction_10730116", "reactome": "R-SPO-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113587", "species_113559" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10730113", "catalyst" ] ], "additional_components": [ "Q10306", "SPAC6C3.04" ] }, "reaction_10757797": { "compartment": "compartment_984", "id": "reaction_10757797", "reactome": "R-SPO-9673054", "name": "PM20D1 hydrolyzes oleoyl-phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9673044", "species_109276" ], "products": [ "species_351993", "species_9673048" ], "modifiers": [ [ "species_10757792", "catalyst" ] ], "additional_components": [ "SPAC24C9.08" ] }, "reaction_10752715": { "compartment": "compartment_5460", "id": "reaction_10752715", "reactome": "R-SPO-6807826", "name": "LDHAL6B reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113557", "species_113529" ], "products": [ "species_113526", "species_6807616" ], "modifiers": [ [ "species_10752712", "catalyst" ] ], "additional_components": [ "SPAC186.08c" ] }, "reaction_10750305": { "compartment": "compartment_70101", "id": "reaction_10750305", "reactome": "R-SPO-6783221", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694130" ], "products": [ "species_29450", "species_29708" ], "modifiers": [ [ "species_10750302", "catalyst" ] ], "additional_components": [ "species_442320", "Q9UT36", "SPAC824.07" ] }, "reaction_10730098": { "compartment": "compartment_5460", "id": "reaction_10730098", "reactome": "R-SPO-70967", "name": "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938", "species_113526" ], "products": [ "species_113594", "species_29376", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730095", "catalyst" ], [ "species_113581", "catalyst" ] ], "additional_components": [ "O13696", "SPAC11G7.03", "species_113527", "Q9USP8", "SPBC902.05c" ] }, "reaction_10730607": { "compartment": "compartment_70101", "id": "reaction_10730607", "reactome": "R-SPO-71849", "name": "LDH tetramer reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_29398" ], "products": [ "species_29708", "species_29360" ], "modifiers": [ [ "species_10729885", "catalyst" ] ], "additional_components": [ "Q9P7P7", "SPAC186.08c" ] }, "reaction_10735414": { "compartment": "compartment_5460", "id": "reaction_10735414", "reactome": "R-SPO-169260", "name": "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735409", "species_31649" ], "products": [ "species_113596", "species_10735411" ], "modifiers": [ [ "species_10735409", "catalyst" ] ], "additional_components": [ "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_113596", "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_31649", "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_113596" ] }, "reaction_10739916": { "compartment": "compartment_5460", "id": "reaction_10739916", "reactome": "R-SPO-451033", "name": "(S)-Malate <=> Fumarate + H2O", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113544" ], "products": [ "species_113521", "species_113588" ], "modifiers": [ [ "species_10730133", "catalyst" ] ], "additional_components": [ "O94552", "SPCC18.18c" ] }, "reaction_10756661": { "compartment": "compartment_70101", "id": "reaction_10756661", "reactome": "R-SPO-9012374", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398" ], "products": [ "species_9012375" ], "modifiers": [ [ "species_10745156", "catalyst" ] ], "additional_components": [ "SPAC1635.01" ] }, "reaction_10730180": { "compartment": "compartment_5460", "id": "reaction_10730180", "reactome": "R-SPO-70997", "name": "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_70958" ], "products": [ "species_29374", "species_113536", "species_113593" ], "modifiers": [ [ "species_10730177", "catalyst" ] ], "additional_components": [ "O13750", "SPAC16E8.17c", "O94415", "SPCC1620.08" ] }, "reaction_10735047": { "compartment": "compartment_70616", "id": "reaction_10735047", "reactome": "R-SPO-164651", "name": "Electron transfer from ubiquinol to cytochrome c of complex III", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76633", "species_10734930", "species_113529", "species_73663" ], "products": [ "species_76633", "species_10734928", "species_163953", "species_73663" ], "modifiers": [ [ "species_10735044", "catalyst" ] ], "additional_components": [ "P00046", "SPCC191.07", "CHEBI:38574", "P00046", "SPCC191.07", "CHEBI:38573", "Q9P7X1", "SPBP23A10.15c", "Q09154", "SPBC16H5.06", "O42932", "SPBC16C6.08c", "P05501", "SPMIT.05", "P50523", "SPAC1782.07", "O74533", "SPCC737.02c", "O59680", "SPBC29A3.18", "O94745", "SPBC18E5.12c", "O74433", "SPCC1682.01" ] }, "reaction_10729888": { "compartment": "compartment_70101", "id": "reaction_10729888", "reactome": "R-SPO-70510", "name": "LDH tetramer oxidises LACT to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_29360" ], "products": [ "species_70106", "species_73473", "species_29398" ], "modifiers": [ [ "species_10729885", "catalyst" ] ], "additional_components": [ "Q9P7P7", "SPAC186.08c" ] }, "reaction_10756645": { "compartment": "compartment_5460", "id": "reaction_10756645", "reactome": "R-SPO-9012016", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587" ], "products": [ "species_29376", "species_113557" ], "modifiers": [ [ "species_10756642", "catalyst" ] ], "additional_components": [ "species_29926", "Q9P7L4", "SPBC21C3.09c" ] }, "reaction_10730328": { "compartment": "compartment_5460", "id": "reaction_10730328", "reactome": "R-SPO-71401", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113594", "species_113526" ], "products": [ "species_29376", "species_70958", "species_29362" ], "modifiers": [ [ "species_10730208", "catalyst" ] ], "additional_components": [ "O94681", "SPBC776.15c", "species_29480", "O00087", "SPAC1002.09c", "CHEBI:17460", "O74378", "SPBC3H7.03c", "species_113596" ] }, "reaction_10740353": { "compartment": "compartment_5460", "id": "reaction_10740353", "reactome": "R-SPO-880007", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_879997" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10740350", "catalyst" ], [ "species_880069", "catalyst" ], [ "species_113527", "catalyst" ], [ "species_880067", "catalyst" ] ], "additional_components": [ "SPBC713.03" ] }, "reaction_10757795": { "compartment": "compartment_984", "id": "reaction_10757795", "reactome": "R-SPO-9673053", "name": "PM20D1 transforms oleoyl-phe from oleate and phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351993", "species_9673048" ], "products": [ "species_9673044", "species_109276" ], "modifiers": [ [ "species_10757792", "catalyst" ] ], "additional_components": [ "SPAC24C9.08" ] }, "reaction_10736322": { "compartment": "compartment_70101", "id": "reaction_10736322", "reactome": "R-SPO-194678", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194634", "species_29368" ], "products": [ "species_29366", "species_194644", "species_29460", "species_29356" ], "modifiers": [ [ "species_10736319", "catalyst" ] ], "additional_components": [ "SPAC13A11.02c" ] }, "reaction_10742192": { "compartment": "compartment_161320", "id": "reaction_10742192", "reactome": "R-SPO-1605736", "name": "Alpha-galactosidase A removes a terminal galactose from alpha-D-galactoside oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605716", "species_1605715" ], "products": [ "species_1605601", "species_1605637" ], "modifiers": [ [ "species_10742189", "catalyst" ] ], "additional_components": [ "Q9URZ0", "SPAC869.07c" ] }, "reaction_10742202": { "compartment": "compartment_876", "id": "reaction_10742202", "reactome": "R-SPO-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10742199", "catalyst" ] ], "additional_components": [ "O74369", "SPBC32F12.01c", "species_29926" ] }, "reaction_10742308": { "compartment": "compartment_876", "id": "reaction_10742308", "reactome": "R-SPO-1640164", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10742305", "catalyst" ] ], "additional_components": [ "SPBC725.05c" ] }, "reaction_10745892": { "compartment": "compartment_70101", "id": "reaction_10745892", "reactome": "R-SPO-5362721", "name": "RDH5,RDH11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_30927" ], "products": [ "species_70106", "species_73473", "species_32737" ], "modifiers": [ [ "species_10745889", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10745878": { "compartment": "compartment_70101", "id": "reaction_10745878", "reactome": "R-SPO-5362522", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975622", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_5334816" ], "modifiers": [ [ "species_10745875", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10745907": { "compartment": "compartment_70101", "id": "reaction_10745907", "reactome": "R-SPO-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10745904", "catalyst" ] ], "additional_components": [ "O74959", "SPCC736.13", "O13822", "SPCC736.13" ] }, "reaction_10745865": { "compartment": "compartment_70101", "id": "reaction_10745865", "reactome": "R-SPO-5362518", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10745862", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10746047": { "compartment": "compartment_70101", "id": "reaction_10746047", "reactome": "R-SPO-5615668", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10745883": { "compartment": "compartment_70101", "id": "reaction_10745883", "reactome": "R-SPO-5362564", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10745880", "catalyst" ] ], "additional_components": [ "species_442320", "P78870", "SPCC13B11.04c", "O74540", "SPCC13B11.04c" ] }, "reaction_10737563": { "compartment": "compartment_7660", "id": "reaction_10737563", "reactome": "R-SPO-212263", "name": "PRC2 trimethylates histone H3 at lysine-27", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10737551" ], "products": [ "species_10737560", "species_77502" ], "modifiers": [ [ "species_10737551", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c" ] }, "reaction_10745441": { "compartment": "compartment_7660", "id": "reaction_10745441", "reactome": "R-SPO-5220959", "name": "TDG excises 5-formylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5221062", "species_10733857" ], "products": [ "species_10733889", "species_5221065" ], "modifiers": [ [ "species_10733857", "catalyst" ] ], "additional_components": [ "SPCC965.05c", "O59825", "SPCC965.05c", "SPCC965.05c" ] }, "reaction_10745443": { "compartment": "compartment_7660", "id": "reaction_10745443", "reactome": "R-SPO-5221061", "name": "TDG excises 5-carboxylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5220996", "species_10733857" ], "products": [ "species_5221064", "species_10733889" ], "modifiers": [ [ "species_10733857", "catalyst" ] ], "additional_components": [ "SPCC965.05c", "O59825", "SPCC965.05c", "SPCC965.05c" ] }, "reaction_10749501": { "compartment": "compartment_70101", "id": "reaction_10749501", "reactome": "R-SPO-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735397" ], "products": [ "species_10735395" ], "modifiers": [ [ "species_10729170", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPAC31G5.13" ] }, "reaction_10749588": { "compartment": "compartment_70101", "id": "reaction_10749588", "reactome": "R-SPO-5693061", "name": "STAMBP binds STAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749579", "species_10749584" ], "products": [ "species_10749586" ], "modifiers": [], "additional_components": [ "O74749", "SPBC1734.08", "O94478", "SPCC1919.11", "SPAC19B12.10", "O74749", "SPBC1734.08", "Q9P371", "SPAC19B12.10", "O94478", "SPCC1919.11" ] }, "reaction_10749982": { "compartment": "compartment_70101", "id": "reaction_10749982", "reactome": "R-SPO-5696547", "name": "STAMBPL1 is a deubiquitinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735397" ], "products": [ "species_10735395" ], "modifiers": [ [ "species_10749979", "catalyst" ], [ "species_10749586", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPAC19B12.10", "O74749", "SPBC1734.08", "Q9P371", "SPAC19B12.10", "O94478", "SPCC1919.11" ] }, "reaction_10736864": { "compartment": "compartment_876", "id": "reaction_10736864", "reactome": "R-SPO-200646", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965" ], "products": [ "species_200716" ], "modifiers": [ [ "species_10736861", "catalyst" ] ], "additional_components": [ "SPAC14C4.07" ] }, "reaction_10736856": { "compartment": "compartment_70101", "id": "reaction_10736856", "reactome": "R-SPO-200644", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_200739" ], "products": [ "species_70106", "species_29364", "species_200640" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10744081": { "compartment": "compartment_70101", "id": "reaction_10744081", "reactome": "R-SPO-3323111", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743659" ], "products": [ "species_10743759" ], "modifiers": [], "additional_components": [ "Q9UUE1", "SPBC17G9.11c", "species_113527", "Q9UUE1", "SPBC17G9.11c", "species_113527" ] }, "reaction_10749713": { "compartment": "compartment_70616", "id": "reaction_10749713", "reactome": "R-SPO-5694137", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693984", "species_113521", "species_159549" ], "products": [ "species_200671", "species_379732" ], "modifiers": [ [ "species_10749710", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c", "O13972", "SPAC24C9.12c" ] }, "reaction_10736843": { "compartment": "compartment_7660", "id": "reaction_10736843", "reactome": "R-SPO-200512", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_200492" ], "products": [ "species_200499", "species_113541" ], "modifiers": [ [ "species_10736840", "catalyst" ] ], "additional_components": [ "species_442320", "Q9UT53", "SPAC806.06c" ] }, "reaction_10740902": { "compartment": "compartment_70101", "id": "reaction_10740902", "reactome": "R-SPO-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965053", "species_113592" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10740897", "catalyst" ] ], "additional_components": [ "species_442320", "O14242", "SPAC6F6.11c" ] }, "reaction_10736380": { "compartment": "compartment_70101", "id": "reaction_10736380", "reactome": "R-SPO-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196767", "species_113592" ], "products": [ "species_196778", "species_111294" ], "modifiers": [ [ "species_10736377", "catalyst" ] ], "additional_components": [ "SPAC1F12.08" ] }, "reaction_10736449": { "compartment": "compartment_70101", "id": "reaction_10736449", "reactome": "R-SPO-197958", "name": "FPGS-2 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_111355" ], "products": [ "species_29370", "species_197969", "species_29372" ], "modifiers": [ [ "species_10736446", "catalyst" ] ], "additional_components": [ "SPBC1709.17" ] }, "reaction_10755126": { "compartment": "compartment_70101", "id": "reaction_10755126", "reactome": "R-SPO-8869633", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10755112", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10743762": { "compartment": "compartment_70101", "id": "reaction_10743762", "reactome": "R-SPO-3095901", "name": "ABCC1 transports cytosolic Cbl to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3000241", "species_29356" ], "products": [ "species_29370", "species_3000125", "species_29372" ], "modifiers": [ [ "species_10737726", "catalyst" ] ], "additional_components": [ "SPAC3F10.11c" ] }, "reaction_10736897": { "compartment": "compartment_70101", "id": "reaction_10736897", "reactome": "R-SPO-200711", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29460", "species_197969" ], "products": [ "species_29370", "species_111353", "species_29372" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10736901": { "compartment": "compartment_70616", "id": "reaction_10736901", "reactome": "R-SPO-200720", "name": "SLC25A32 transports THF from mitochondrial matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671" ], "products": [ "species_111355" ], "modifiers": [ [ "species_10736884", "catalyst" ] ], "additional_components": [ "SPBC27B12.09c" ] }, "reaction_10736383": { "compartment": "compartment_70101", "id": "reaction_10736383", "reactome": "R-SPO-196773", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196778" ], "products": [ "species_76194", "species_29370" ], "modifiers": [ [ "species_10736377", "catalyst" ] ], "additional_components": [ "SPAC1F12.08" ] }, "reaction_10740904": { "compartment": "compartment_70101", "id": "reaction_10740904", "reactome": "R-SPO-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965131", "species_113592" ], "products": [ "species_29370", "species_29390" ], "modifiers": [ [ "species_10740897", "catalyst" ] ], "additional_components": [ "species_442320", "O14242", "SPAC6F6.11c" ] }, "reaction_10744750": { "compartment": "compartment_70101", "id": "reaction_10744750", "reactome": "R-SPO-4167511", "name": "HLCS biotinylates ACACB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_10744748", "species_113592" ], "products": [ "species_111294", "species_76577", "species_10736807" ], "modifiers": [ [ "species_10743664", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527", "P78820", "SPAC56E4.04c", "species_113527", "SPBC30D10.07c" ] }, "reaction_10736866": { "compartment": "compartment_70101", "id": "reaction_10736866", "reactome": "R-SPO-200651", "name": "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_200739" ], "products": [ "species_200736", "species_197969" ], "modifiers": [ [ "species_10730229", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c" ] }, "reaction_10740888": { "compartment": "compartment_70101", "id": "reaction_10740888", "reactome": "R-SPO-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740872", "species_111707" ], "products": [ "species_10740877", "species_29432" ], "modifiers": [ [ "species_10740885", "catalyst" ] ], "additional_components": [ "species_442320", "Q09810", "SPAC2G11.10c", "species_442320", "Q09810", "SPAC2G11.10c", "O74351", "SPBC21D10.11c" ] }, "reaction_10740914": { "compartment": "compartment_70101", "id": "reaction_10740914", "reactome": "R-SPO-965019", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964952", "species_29368" ], "products": [ "species_29408", "species_29390" ], "modifiers": [ [ "species_10740911", "catalyst" ] ], "additional_components": [ "Q9UTQ1", "SPAC1093.02", "species_73524" ] }, "reaction_10736894": { "compartment": "compartment_5460", "id": "reaction_10736894", "reactome": "R-SPO-200682", "name": "Mitochondrial FPGS-1 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_200671", "species_113593" ], "products": [ "species_113548", "species_200679", "species_113581" ], "modifiers": [ [ "species_10736891", "catalyst" ] ], "additional_components": [ "SPBC1709.17" ] }, "reaction_10736836": { "compartment": "compartment_5460", "id": "reaction_10736836", "reactome": "R-SPO-200474", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938083", "species_113593" ], "products": [ "species_8938090", "species_159450" ], "modifiers": [ [ "species_10736833", "catalyst" ] ], "additional_components": [ "Q9UT53", "SPAC806.06c", "species_29926" ] }, "reaction_10740900": { "compartment": "compartment_70101", "id": "reaction_10740900", "reactome": "R-SPO-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10740897", "catalyst" ] ], "additional_components": [ "species_442320", "O14242", "SPAC6F6.11c" ] }, "reaction_10736905": { "compartment": "compartment_70101", "id": "reaction_10736905", "reactome": "R-SPO-200735", "name": "SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_197969" ], "products": [ "species_29424", "species_200739" ], "modifiers": [ [ "species_10730229", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c" ] }, "reaction_10736907": { "compartment": "compartment_70101", "id": "reaction_10736907", "reactome": "R-SPO-200740", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200640", "species_29356" ], "products": [ "species_111353" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10752500": { "compartment": "compartment_5460", "id": "reaction_10752500", "reactome": "R-SPO-6801456", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5389850", "species_113548", "species_113581" ], "products": [ "species_200671", "species_6801451", "species_113593" ], "modifiers": [ [ "species_10750054", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16", "O43007", "SPBC2G2.08" ] }, "reaction_10736658": { "compartment": "compartment_70101", "id": "reaction_10736658", "reactome": "R-SPO-198845", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736644", "species_1497805" ], "products": [ "species_198816", "species_10736642" ], "modifiers": [ [ "species_10736644", "catalyst" ] ], "additional_components": [ "species_189444", "Q9USM6", "SPCC16A11.10c", "CHEBI:36144", "Q9USM6", "SPCC16A11.10c", "species_189444", "Q9USM6", "SPCC16A11.10c" ] }, "reaction_10736899": { "compartment": "compartment_70101", "id": "reaction_10736899", "reactome": "R-SPO-200718", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200640" ], "products": [ "species_29366", "species_200739" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10743673": { "compartment": "compartment_70101", "id": "reaction_10743673", "reactome": "R-SPO-2993814", "name": "HLCS biotinylates ACACA:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_10743671", "species_113592" ], "products": [ "species_10733321", "species_111294", "species_76577" ], "modifiers": [ [ "species_10743664", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527", "P78820", "SPAC56E4.04c", "species_113527", "SPBC30D10.07c" ] }, "reaction_10736431": { "compartment": "compartment_70101", "id": "reaction_10736431", "reactome": "R-SPO-197235", "name": "NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_197220" ], "products": [ "species_197256", "species_111294" ], "modifiers": [ [ "species_10736428", "catalyst" ] ], "additional_components": [ "Q9UT53", "SPAC806.06c", "species_29926" ] }, "reaction_10736372": { "compartment": "compartment_70101", "id": "reaction_10736372", "reactome": "R-SPO-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111707", "species_196786" ], "products": [ "species_196834", "species_111294", "species_76577" ], "modifiers": [ [ "species_10736369", "catalyst" ] ], "additional_components": [ "Q9USK7", "SPCC4B3.18" ] }, "reaction_10740916": { "compartment": "compartment_70101", "id": "reaction_10740916", "reactome": "R-SPO-965079", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965146", "species_29368", "species_29356" ], "products": [ "species_29408", "species_31633", "species_29390" ], "modifiers": [ [ "species_10740911", "catalyst" ] ], "additional_components": [ "Q9UTQ1", "SPAC1093.02", "species_73524" ] }, "reaction_10736441": { "compartment": "compartment_70101", "id": "reaction_10736441", "reactome": "R-SPO-197271", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197256", "species_29472", "species_113592", "species_29356" ], "products": [ "species_29404", "species_111294", "species_29360", "species_76577" ], "modifiers": [ [ "species_10736438", "catalyst" ] ], "additional_components": [ "O74940", "SPCC553.02" ] }, "reaction_10743667": { "compartment": "compartment_70101", "id": "reaction_10743667", "reactome": "R-SPO-2993802", "name": "HLCS biotinylates PC:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_113592", "species_10743654" ], "products": [ "species_10743659", "species_111294", "species_76577" ], "modifiers": [ [ "species_10743664", "catalyst" ] ], "additional_components": [ "Q9UUE1", "SPBC17G9.11c", "species_113527", "Q9UUE1", "SPBC17G9.11c", "species_113527", "SPBC30D10.07c" ] }, "reaction_10736903": { "compartment": "compartment_876", "id": "reaction_10736903", "reactome": "R-SPO-200729", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716" ], "products": [ "species_197965" ], "modifiers": [ [ "species_10736861", "catalyst" ] ], "additional_components": [ "SPAC14C4.07" ] }, "reaction_10752956": { "compartment": "compartment_70101", "id": "reaction_10752956", "reactome": "R-SPO-6808496", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_111353", "species_29356" ], "products": [ "species_70106", "species_29364", "species_113528", "species_197969" ], "modifiers": [ [ "species_10752953", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10752498": { "compartment": "compartment_70101", "id": "reaction_10752498", "reactome": "R-SPO-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_70106", "species_29370", "species_200640", "species_29372" ], "modifiers": [ [ "species_10752495", "catalyst" ] ], "additional_components": [ "SPBC1703.08c" ] }, "reaction_10757959": { "compartment": "compartment_70101", "id": "reaction_10757959", "reactome": "R-SPO-9709098", "name": "DHFR dimer reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_197965" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10757956", "catalyst" ] ], "additional_components": [ "P36591", "SPCC1223.08c" ] }, "reaction_10755120": { "compartment": "compartment_70101", "id": "reaction_10755120", "reactome": "R-SPO-8869607", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10755117", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10750057": { "compartment": "compartment_5460", "id": "reaction_10750057", "reactome": "R-SPO-5696839", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_6801451", "species_113593" ], "products": [ "species_5389850", "species_113548", "species_113581" ], "modifiers": [ [ "species_10750054", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16", "O43007", "SPBC2G2.08" ] }, "reaction_10736457": { "compartment": "compartment_70101", "id": "reaction_10736457", "reactome": "R-SPO-197963", "name": "DHFR2 reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_197965" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10736454", "catalyst" ] ], "additional_components": [ "SPCC1223.08c" ] }, "reaction_10755856": { "compartment": "compartment_70101", "id": "reaction_10755856", "reactome": "R-SPO-8939959", "name": "NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869353" ], "products": [ "species_111294", "species_29360" ], "modifiers": [ [ "species_10736428", "catalyst" ] ], "additional_components": [ "Q9UT53", "SPAC806.06c", "species_29926" ] }, "reaction_10736889": { "compartment": "compartment_70101", "id": "reaction_10736889", "reactome": "R-SPO-200681", "name": "FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_200665" ], "products": [ "species_29370", "species_174404", "species_29372" ], "modifiers": [ [ "species_10736446", "catalyst" ] ], "additional_components": [ "SPBC1709.17" ] }, "reaction_10736421": { "compartment": "compartment_70101", "id": "reaction_10736421", "reactome": "R-SPO-197198", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29360" ], "products": [ "species_29370", "species_29366" ], "modifiers": [ [ "species_10736418", "catalyst" ] ], "additional_components": [ "species_442320", "O13863", "SPAC1B1.02c" ] }, "reaction_10755115": { "compartment": "compartment_70101", "id": "reaction_10755115", "reactome": "R-SPO-8869606", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10755112", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10736655": { "compartment": "compartment_70101", "id": "reaction_10736655", "reactome": "R-SPO-198824", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10736642" ], "products": [ "species_29360", "species_10736644" ], "modifiers": [ [ "species_10736652", "catalyst" ] ], "additional_components": [ "CHEBI:36144", "Q9USM6", "SPCC16A11.10c", "species_189444", "Q9USM6", "SPCC16A11.10c", "O74557", "SPCC970.03", "species_113596" ] }, "reaction_10736869": { "compartment": "compartment_70101", "id": "reaction_10736869", "reactome": "R-SPO-200661", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111353" ], "products": [ "species_200640", "species_29356" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10755480": { "compartment": "compartment_17927", "id": "reaction_10755480", "reactome": "R-SPO-8875838", "name": "SLC25A19 transports ThDP from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29480" ], "products": [ "species_8878387" ], "modifiers": [ [ "species_10755477", "catalyst" ] ], "additional_components": [ "SPBC1604.04" ] }, "reaction_10755123": { "compartment": "compartment_70101", "id": "reaction_10755123", "reactome": "R-SPO-8869627", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10755117", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10736459": { "compartment": "compartment_70101", "id": "reaction_10736459", "reactome": "R-SPO-197972", "name": "DHF is reduced to tetrahydrofolate (THF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_73604" ], "products": [ "species_29366", "species_111355" ], "modifiers": [ [ "species_10736454", "catalyst" ] ], "additional_components": [ "SPCC1223.08c" ] }, "reaction_10736879": { "compartment": "compartment_70101", "id": "reaction_10736879", "reactome": "R-SPO-200676", "name": "MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200739" ], "products": [ "species_29366", "species_174404" ], "modifiers": [ [ "species_10736876", "catalyst" ] ], "additional_components": [ "Q10258", "SPAC56F8.10" ] }, "reaction_10752948": { "compartment": "compartment_5460", "id": "reaction_10752948", "reactome": "R-SPO-6808487", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6808499", "species_113563", "species_113521" ], "products": [ "species_113600", "species_200679", "species_29376", "species_113529" ], "modifiers": [ [ "species_10752945", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10736666": { "compartment": "compartment_70616", "id": "reaction_10736666", "reactome": "R-SPO-199216", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194" ], "products": [ "species_29374" ], "modifiers": [ [ "species_10736663", "catalyst" ] ], "additional_components": [ "SPAC17H9.08" ] }, "reaction_10736327": { "compartment": "compartment_70101", "id": "reaction_10736327", "reactome": "R-SPO-194698", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644" ], "products": [ "species_29366", "species_194633" ], "modifiers": [ [ "species_10736324", "catalyst" ] ], "additional_components": [ "SPBC16G5.18" ] }, "reaction_10736094": { "compartment": "compartment_70101", "id": "reaction_10736094", "reactome": "R-SPO-191352", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191374" ], "products": [ "species_76194", "species_29366", "species_191424" ], "modifiers": [ [ "species_10736091", "catalyst" ] ], "additional_components": [ "Q10283", "SPCC162.09c" ] }, "reaction_10736314": { "compartment": "compartment_13231", "id": "reaction_10736314", "reactome": "R-SPO-194674", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194681", "species_194688", "species_194725" ], "products": [ "species_194704", "species_194668" ], "modifiers": [ [ "species_10736311", "catalyst" ] ], "additional_components": [ "SPBC16G5.18" ] }, "reaction_10736304": { "compartment": "compartment_70101", "id": "reaction_10736304", "reactome": "R-SPO-194642", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194735", "species_29360" ], "products": [ "species_70106", "species_73473", "species_113528", "species_194667" ], "modifiers": [ [ "species_10736301", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736084": { "compartment": "compartment_70101", "id": "reaction_10736084", "reactome": "R-SPO-191323", "name": "HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191293", "species_29356", "species_76183" ], "products": [ "species_70106", "species_76194", "species_191374" ], "modifiers": [ [ "species_10736081", "catalyst" ] ], "additional_components": [ "SPAC4F8.14c" ] }, "reaction_10736329": { "compartment": "compartment_70101", "id": "reaction_10736329", "reactome": "R-SPO-194718", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_194657" ], "products": [ "species_73473", "species_70106", "species_194661", "species_113528" ], "modifiers": [ [ "species_10736301", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736076": { "compartment": "compartment_70101", "id": "reaction_10736076", "reactome": "R-SPO-191303", "name": "FDPS dimer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191409" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10736073", "catalyst" ] ], "additional_components": [ "species_29926", "O14230", "SPAC6F12.13c" ] }, "reaction_10745569": { "compartment": "compartment_17957", "id": "reaction_10745569", "reactome": "R-SPO-5250531", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384" ], "products": [ "species_171095" ], "modifiers": [ [ "species_10745566", "catalyst" ] ], "additional_components": [ "SPAPB1A10.15" ] }, "reaction_10736079": { "compartment": "compartment_70101", "id": "reaction_10736079", "reactome": "R-SPO-191322", "name": "FDPS dimer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191324" ], "products": [ "species_191409", "species_111294" ], "modifiers": [ [ "species_10736073", "catalyst" ] ], "additional_components": [ "species_29926", "O14230", "SPAC6F12.13c" ] }, "reaction_10736306": { "compartment": "compartment_70101", "id": "reaction_10736306", "reactome": "R-SPO-194669", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194723", "species_29368" ], "products": [ "species_29366", "species_29356", "species_194657" ], "modifiers": [ [ "species_10736296", "catalyst" ] ], "additional_components": [ "SPAC630.08c" ] }, "reaction_10736102": { "compartment": "compartment_70101", "id": "reaction_10736102", "reactome": "R-SPO-191366", "name": "Squalene 2,3-epoxide cyclizes, forming lanosterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191309" ], "products": [ "species_194634" ], "modifiers": [ [ "species_10736099", "catalyst" ] ], "additional_components": [ "SPAC13G7.01c" ] }, "reaction_10736134": { "compartment": "compartment_70101", "id": "reaction_10736134", "reactome": "R-SPO-191405", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191385" ], "products": [ "species_191265", "species_111294" ], "modifiers": [ [ "species_10736129", "catalyst" ] ], "additional_components": [ "P36596", "SPBC646.05c", "species_29926" ] }, "reaction_10736112": { "compartment": "compartment_70101", "id": "reaction_10736112", "reactome": "R-SPO-191380", "name": "Mevalonate is phosphorylated to mevalonate-5-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191424" ], "products": [ "species_29370", "species_191296" ], "modifiers": [ [ "species_10736109", "catalyst" ] ], "additional_components": [ "Q09780", "SPAC13G6.11c" ] }, "reaction_10736122": { "compartment": "compartment_70101", "id": "reaction_10736122", "reactome": "R-SPO-191382", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362" ], "products": [ "species_191324" ], "modifiers": [ [ "species_10736119", "catalyst" ] ], "additional_components": [ "Q10132", "SPBC106.15", "species_29926" ] }, "reaction_10736299": { "compartment": "compartment_70101", "id": "reaction_10736299", "reactome": "R-SPO-194641", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644", "species_29368" ], "products": [ "species_29366", "species_194735", "species_29356" ], "modifiers": [ [ "species_10736296", "catalyst" ] ], "additional_components": [ "SPAC630.08c" ] }, "reaction_10736064": { "compartment": "compartment_70101", "id": "reaction_10736064", "reactome": "R-SPO-191299", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191269", "species_29368" ], "products": [ "species_29366", "species_191309", "species_29356" ], "modifiers": [ [ "species_10736061", "catalyst" ] ], "additional_components": [ "Q9C1W3", "SPBC713.12", "species_113596" ] }, "reaction_10736132": { "compartment": "compartment_70101", "id": "reaction_10736132", "reactome": "R-SPO-191402", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_191265", "species_29364" ], "products": [ "species_29366", "species_191269", "species_111294" ], "modifiers": [ [ "species_10736129", "catalyst" ] ], "additional_components": [ "P36596", "SPBC646.05c", "species_29926" ] }, "reaction_10735725": { "compartment": "compartment_7660", "id": "reaction_10735725", "reactome": "R-SPO-176318", "name": "Loading of claspin onto DNA during replication origin firing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735715", "species_10728877" ], "products": [ "species_10735717" ], "modifiers": [], "additional_components": [ "SPAC694.06c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9P7T4", "SPAC694.06c" ] }, "reaction_10735710": { "compartment": "compartment_7660", "id": "reaction_10735710", "reactome": "R-SPO-176264", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735705", "species_10735676" ], "products": [ "species_10735707" ], "modifiers": [ [ "species_10735676", "catalyst" ] ], "additional_components": [ "P26306", "SPAC664.07c", "P78955", "SPAC20G4.04c", "P22193", "SPAC1952.07", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13", "P26306", "SPAC664.07c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "P78955", "SPAC20G4.04c", "O14003", "SPAC27E2.10c", "P22193", "SPAC1952.07", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13" ] }, "reaction_10732950": { "compartment": "compartment_7660", "id": "reaction_10732950", "reactome": "R-SPO-75010", "name": "Phosphorylation of Cdc25C at Ser 216 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732945", "species_29358" ], "products": [ "species_113582", "species_10732948" ], "modifiers": [ [ "species_10729605", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "O13945", "SPAC23H4.02", "O74536", "SPCC74.03c" ] }, "reaction_10735678": { "compartment": "compartment_7660", "id": "reaction_10735678", "reactome": "R-SPO-176101", "name": "Recruitment of Rad17-RFC complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735674", "species_10735672" ], "products": [ "species_10735676" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "P50531", "SPAC14C4.13", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13" ] }, "reaction_10735686": { "compartment": "compartment_7660", "id": "reaction_10735686", "reactome": "R-SPO-176175", "name": "Stalling of DNA replication fork and RPA binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729504", "species_176104" ], "products": [ "species_10735674" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c" ] }, "reaction_10739846": { "compartment": "compartment_70101", "id": "reaction_10739846", "reactome": "R-SPO-450400", "name": "ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450597", "species_10739831", "species_10739842" ], "products": [ "species_10739844" ], "modifiers": [], "additional_components": [ "SPAC2F3.06c", "SPBC1718.07c", "P47979", "SPBC1718.07c", "O14089", "SPAC2F3.06c" ] }, "reaction_10744332": { "compartment": "compartment_70101", "id": "reaction_10744332", "reactome": "R-SPO-3371591", "name": "Trimerization of cytosolic HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744185" ], "products": [ "species_10744288" ], "modifiers": [ [ "species_10734704", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10" ] }, "reaction_10744290": { "compartment": "compartment_70101", "id": "reaction_10744290", "reactome": "R-SPO-3371527", "name": "HSF1 trimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744288" ], "products": [ "species_10744252" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10745134": { "compartment": "compartment_7660", "id": "reaction_10745134", "reactome": "R-SPO-5082409", "name": "Dissociation of HSF1:HSP90 complex in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745132" ], "products": [ "species_10745124", "species_10745130", "species_10745102" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "P41887", "SPAC926.04c", "Q02953", "SPAC2E12.02", "SPAC9E9.13", "P41887", "SPAC926.04c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10745615": { "compartment": "compartment_70101", "id": "reaction_10745615", "reactome": "R-SPO-5324632", "name": "Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745610", "species_5324631" ], "products": [ "species_10745612", "species_10744185", "species_10744270", "species_10737648" ], "modifiers": [ [ "species_10745610", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "Q9P3A7", "SPAC1565.08", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "P56523", "SPBC800.03", "Q9P3A7", "SPAC1565.08", "P56523", "SPBC800.03", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "SPAC9E9.13", "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "Q9P3A7", "SPAC1565.08", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "P56523", "SPBC800.03" ] }, "reaction_10745104": { "compartment": "compartment_7660", "id": "reaction_10745104", "reactome": "R-SPO-5082391", "name": "Trimerization of HSF1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745102" ], "products": [ "species_10744252" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10744324": { "compartment": "compartment_70101", "id": "reaction_10744324", "reactome": "R-SPO-3371586", "name": "Dissociation of cytosolic HSF1:HSP90 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744322" ], "products": [ "species_10744185", "species_10744270", "species_10737648" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "SPAC9E9.13" ] }, "reaction_10730060": { "compartment": "compartment_5460", "id": "reaction_10730060", "reactome": "R-SPO-70724", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_508190" ], "products": [ "species_113552", "species_508181" ], "modifiers": [ [ "species_10730057", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "O14370", "SPBC428.02c" ] }, "reaction_10730068": { "compartment": "compartment_5460", "id": "reaction_10730068", "reactome": "R-SPO-70881", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71847", "species_113521" ], "products": [ "species_29374", "species_573404" ], "modifiers": [ [ "species_10730065", "catalyst" ] ], "additional_components": [ "SPBC2D10.09" ] }, "reaction_10730052": { "compartment": "compartment_70101", "id": "reaction_10730052", "reactome": "R-SPO-70723", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_508182", "species_29406" ], "products": [ "species_29404", "species_508187" ], "modifiers": [ [ "species_10730049", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "O14370", "SPBC428.02c" ] }, "reaction_10756331": { "compartment": "compartment_5460", "id": "reaction_10756331", "reactome": "R-SPO-8952873", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_77343", "species_113529" ], "products": [ "species_113563", "species_77308" ], "modifiers": [ [ "species_10756328", "catalyst" ] ], "additional_components": [ "Q10488", "SPAC26F1.04c" ] }, "reaction_10744576": { "compartment": "compartment_7660", "id": "reaction_10744576", "reactome": "R-SPO-3782655", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10744514" ], "products": [ "species_5566518", "species_10744522" ], "modifiers": [ [ "species_10744573", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "SPBC800.03" ] }, "reaction_10744558": { "compartment": "compartment_7660", "id": "reaction_10744558", "reactome": "R-SPO-3769447", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10744514" ], "products": [ "species_5566518", "species_10744522" ], "modifiers": [ [ "species_10744553", "catalyst" ], [ "species_10744556", "inhibitor" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "O94405", "SPCC126.13c", "O74365", "SPBC30B4.04c", "LigandDisplayForward?ligandId=7489", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "LigandDisplayForward?ligandId=6852", "O94405", "SPCC126.13c", "LigandDisplayForward?ligandId=7496", "O74365", "SPBC30B4.04c" ] }, "reaction_10757824": { "compartment": "compartment_7660", "id": "reaction_10757824", "reactome": "R-SPO-9679787", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744553", "species_9679795" ], "products": [ "species_10744556" ], "modifiers": [], "additional_components": [ "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "O94405", "SPCC126.13c", "O74365", "SPBC30B4.04c", "LigandDisplayForward?ligandId=7489", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "LigandDisplayForward?ligandId=6852", "LigandDisplayForward?ligandId=7496", "LigandDisplayForward?ligandId=7489", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "LigandDisplayForward?ligandId=6852", "O94405", "SPCC126.13c", "LigandDisplayForward?ligandId=7496", "O74365", "SPBC30B4.04c" ] }, "reaction_10746196": { "compartment": "compartment_70101", "id": "reaction_10746196", "reactome": "R-SPO-5623667", "name": "PDPK1 phosphorylates PKN1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746165", "species_113592" ], "products": [ "species_29370", "species_10746193", "species_10738584", "species_10733718" ], "modifiers": [ [ "species_10746165", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "species_179838", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_179838", "Q12701", "SPCC576.15c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "species_179838", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c" ] }, "reaction_10746163": { "compartment": "compartment_876", "id": "reaction_10746163", "reactome": "R-SPO-5623622", "name": "RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746159", "species_10738584" ], "products": [ "species_10746161" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "P36582", "SPAC17G8.14c" ] }, "reaction_10746167": { "compartment": "compartment_876", "id": "reaction_10746167", "reactome": "R-SPO-5623632", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733718", "species_10746161" ], "products": [ "species_10746165" ], "modifiers": [], "additional_components": [ "species_179838", "Q12701", "SPCC576.15c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "species_179838", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c" ] }, "reaction_10746791": { "compartment": "compartment_70101", "id": "reaction_10746791", "reactome": "R-SPO-5671749", "name": "p-T774-PKN1 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746786" ], "products": [ "species_29370", "species_10746175", "species_10732952" ], "modifiers": [ [ "species_10746786", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P06652", "SPAC24H6.05", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "SPAC24H6.05", "P36583", "SPBC12D12.04c", "P06652", "SPAC24H6.05", "P36582", "SPAC17G8.14c" ] }, "reaction_10746788": { "compartment": "compartment_70101", "id": "reaction_10746788", "reactome": "R-SPO-5671737", "name": "p-T774-PKN1 binds CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746175", "species_10734625" ], "products": [ "species_10746786" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "SPAC24H6.05", "P36583", "SPBC12D12.04c", "P06652", "SPAC24H6.05", "P36582", "SPAC17G8.14c" ] }, "reaction_10756168": { "compartment": "compartment_70101", "id": "reaction_10756168", "reactome": "R-SPO-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749457" ], "products": [ "species_10749455", "species_10749446" ], "modifiers": [], "additional_components": [ "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c", "SPBC12D12.08c", "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c" ] }, "reaction_10756413": { "compartment": "compartment_70101", "id": "reaction_10756413", "reactome": "R-SPO-8955241", "name": "CAND1 binds cytosolic CRL E3 ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749492", "species_10756409" ], "products": [ "species_10756411" ], "modifiers": [], "additional_components": [ "SPAC1565.07c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9USX9", "SPBC1861.07", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "P10815", "SPBC582.03", "Q10311", "SPAC6C3.08", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "Q9UTL5", "SPAC144.09c", "Q9P3A8", "SPAC1565.07c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9USX9", "SPBC1861.07", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "P10815", "SPBC582.03", "Q10311", "SPAC6C3.08", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10749462": { "compartment": "compartment_70101", "id": "reaction_10749462", "reactome": "R-SPO-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749453", "species_29356" ], "products": [ "species_10749457", "species_10749459" ], "modifiers": [ [ "species_10749453", "catalyst" ] ], "additional_components": [ "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c", "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c", "SPBC12D12.08c", "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756192": { "compartment": "compartment_70101", "id": "reaction_10756192", "reactome": "R-SPO-8951656", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749455", "species_113592", "species_10756185" ], "products": [ "species_10756190", "species_111294", "species_76577" ], "modifiers": [], "additional_components": [ "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756321": { "compartment": "compartment_7660", "id": "reaction_10756321", "reactome": "R-SPO-8952638", "name": "AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756294" ], "products": [ "species_10756296", "species_10756318" ], "modifiers": [ [ "species_10756294", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "Q8WZK4", "SPBC839.03c", "SPCC777.10c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O14399", "SPBC12D12.08c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "Q8WZK4", "SPBC839.03c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "Q8WZK4", "SPBC839.03c" ] }, "reaction_10756214": { "compartment": "compartment_70101", "id": "reaction_10756214", "reactome": "R-SPO-8951751", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756195", "species_10756190" ], "products": [ "species_10756197" ], "modifiers": [], "additional_components": [ "SPCC777.10c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756208": { "compartment": "compartment_70101", "id": "reaction_10756208", "reactome": "R-SPO-8951661", "name": "Transfer of NEDD8 to AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756197" ], "products": [ "species_10756205", "species_10756185" ], "modifiers": [ [ "species_10756197", "catalyst" ] ], "additional_components": [ "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756250": { "compartment": "compartment_70101", "id": "reaction_10756250", "reactome": "R-SPO-8952618", "name": "AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756235" ], "products": [ "species_10756195", "species_10756247" ], "modifiers": [ [ "species_10756235", "catalyst" ] ], "additional_components": [ "O94289", "SPBC887.04c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O74531", "SPCC1827.08c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "O74549", "SPCC777.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O14399", "SPBC12D12.08c", "Q8WZK4", "SPBC839.03c", "SPCC777.10c", "O94289", "SPBC887.04c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O74531", "SPCC1827.08c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O14399", "SPBC12D12.08c", "Q8WZK4", "SPBC839.03c", "O94289", "SPBC887.04c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O74531", "SPCC1827.08c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "O74549", "SPCC777.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O14399", "SPBC12D12.08c", "Q8WZK4", "SPBC839.03c" ] }, "reaction_10756419": { "compartment": "compartment_7660", "id": "reaction_10756419", "reactome": "R-SPO-8955245", "name": "CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756415", "species_10756280" ], "products": [ "species_10756417" ], "modifiers": [], "additional_components": [ "SPAC1565.07c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "O13807", "SPAC17H9.10c", "Q9P3A8", "SPAC1565.07c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08" ] }, "reaction_10756188": { "compartment": "compartment_70101", "id": "reaction_10756188", "reactome": "R-SPO-8951648", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749455", "species_10756175", "species_113592" ], "products": [ "species_111294", "species_10756185", "species_76577" ], "modifiers": [ [ "species_10756175", "catalyst" ] ], "additional_components": [ "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c" ] }, "reaction_10754241": { "compartment": "compartment_70101", "id": "reaction_10754241", "reactome": "R-SPO-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754239" ], "products": [ "species_10729083", "species_10732101" ], "modifiers": [ [ "species_10754226", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09879", "SPCC188.08c", "Q10171", "SPAC27F1.03c" ] }, "reaction_10754194": { "compartment": "compartment_70101", "id": "reaction_10754194", "reactome": "R-SPO-8852134", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741355", "species_113592", "species_10729165" ], "products": [ "species_10754094", "species_111294" ], "modifiers": [ [ "species_10741355", "catalyst" ] ], "additional_components": [ "SPBC1604.21c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC1604.21c" ] }, "reaction_10754183": { "compartment": "compartment_7660", "id": "reaction_10754183", "reactome": "R-SPO-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754148", "species_10754162" ], "products": [ "species_10754181", "species_10753992" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P23566", "SPAC18B11.07c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH07", "SPAC1805.12c", "P23566", "SPAC18B11.07c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10753994": { "compartment": "compartment_7660", "id": "reaction_10753994", "reactome": "R-SPO-8852128", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10753862", "species_10729044" ], "products": [ "species_113541", "species_10753992" ], "modifiers": [], "additional_components": [ "SPBC1604.21c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754144": { "compartment": "compartment_70101", "id": "reaction_10754144", "reactome": "R-SPO-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753996", "species_10754092" ], "products": [ "species_10754094", "species_10754142" ], "modifiers": [], "additional_components": [ "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9Y818", "SPBC1105.09", "P0C8R3", "SPAC589.10c", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754254": { "compartment": "compartment_70101", "id": "reaction_10754254", "reactome": "R-SPO-8853515", "name": "OTULIN,USP5 cleaves UBC yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754251" ], "products": [ "species_10729083", "species_10729113", "species_10729093", "species_10729103", "species_10729163", "species_10729153", "species_10729143", "species_10729133", "species_10729123" ], "modifiers": [ [ "species_10748788", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC6B1.06c" ] }, "reaction_10754191": { "compartment": "compartment_70101", "id": "reaction_10754191", "reactome": "R-SPO-8852133", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754094" ], "products": [ "species_10753998", "species_76577" ], "modifiers": [ [ "species_10754094", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754188": { "compartment": "compartment_70101", "id": "reaction_10754188", "reactome": "R-SPO-8852132", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753998", "species_10729165" ], "products": [ "species_10754092", "species_111294" ], "modifiers": [ [ "species_10753998", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754196": { "compartment": "compartment_7660", "id": "reaction_10754196", "reactome": "R-SPO-8852136", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753992" ], "products": [ "species_10754146", "species_164121" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754185": { "compartment": "compartment_7660", "id": "reaction_10754185", "reactome": "R-SPO-8852131", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754146", "species_29358", "species_10729044" ], "products": [ "species_10754148", "species_113541" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754266": { "compartment": "compartment_70101", "id": "reaction_10754266", "reactome": "R-SPO-8853529", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754264" ], "products": [ "species_10729083", "species_10729093", "species_10729103" ], "modifiers": [ [ "species_10748788", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC6B1.06c" ] }, "reaction_10754229": { "compartment": "compartment_70101", "id": "reaction_10754229", "reactome": "R-SPO-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729083" ], "products": [ "species_10729083", "species_10731576" ], "modifiers": [ [ "species_10754226", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09879", "SPCC188.08c", "Q10171", "SPAC27F1.03c" ] }, "reaction_10732286": { "compartment": "compartment_70101", "id": "reaction_10732286", "reactome": "R-SPO-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_111627", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_29372", "species_111647" ], "modifiers": [ [ "species_10732277", "catalyst" ] ], "additional_components": [ "O94313", "SPBC215.08c", "Q09794", "SPAC22G7.06c" ] }, "reaction_10732266": { "compartment": "compartment_70101", "id": "reaction_10732266", "reactome": "R-SPO-73569", "name": "DHODH:FMN oxidises (S)-DHO to orotate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_76630" ], "products": [ "species_76633", "species_76632" ], "modifiers": [ [ "species_10732263", "catalyst" ] ], "additional_components": [ "species_73524", "P32747", "SPAC57A10.12c" ] }, "reaction_10732280": { "compartment": "compartment_70101", "id": "reaction_10732280", "reactome": "R-SPO-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111628" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10732277", "catalyst" ] ], "additional_components": [ "O94313", "SPBC215.08c", "Q09794", "SPAC22G7.06c" ] }, "reaction_10732283": { "compartment": "compartment_70101", "id": "reaction_10732283", "reactome": "R-SPO-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_111647" ], "products": [ "species_70106", "species_29372", "species_111628" ], "modifiers": [ [ "species_10732277", "catalyst" ] ], "additional_components": [ "O94313", "SPBC215.08c", "Q09794", "SPAC22G7.06c" ] }, "reaction_10746504": { "compartment": "compartment_7660", "id": "reaction_10746504", "reactome": "R-SPO-5653780", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746500", "species_10746496" ], "products": [ "species_10746502" ], "modifiers": [], "additional_components": [ "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "O60079", "SPCC1494.05c", "Q9USM5", "SPCC16A11.12c", "O60079", "SPCC1494.05c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "Q9USM5", "SPCC16A11.12c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c" ] }, "reaction_10746510": { "compartment": "compartment_7660", "id": "reaction_10746510", "reactome": "R-SPO-5653838", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746506", "species_10734037" ], "products": [ "species_10746508" ], "modifiers": [], "additional_components": [ "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "C6Y4D0", "SPCC16C4.22", "Q03392", "SPBC16D10.09" ] }, "reaction_10733936": { "compartment": "compartment_7660", "id": "reaction_10733936", "reactome": "R-SPO-110234", "name": "Cleavage of ethenocytosine by TDG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733933" ], "products": [ "species_10733889", "species_110233" ], "modifiers": [ [ "species_10733933", "catalyst" ] ], "additional_components": [ "O59825", "SPCC965.05c", "O59825", "SPCC965.05c", "O59825", "SPCC965.05c" ] }, "reaction_10734052": { "compartment": "compartment_7660", "id": "reaction_10734052", "reactome": "R-SPO-110368", "name": "POLD,POLE-mediated DNA strand displacement synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10734049" ], "products": [ "species_10734045", "species_113541" ], "modifiers": [ [ "species_10734049", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "P39750", "SPAC3G6.06c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "P39750", "SPAC3G6.06c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "P39750", "SPAC3G6.06c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10733885": { "compartment": "compartment_7660", "id": "reaction_10733885", "reactome": "R-SPO-110217", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733882" ], "products": [ "species_10733875", "species_110216" ], "modifiers": [ [ "species_10733882", "catalyst" ] ], "additional_components": [ "O74834", "SPCC1183.06", "O74834", "SPCC1183.06", "O74834", "SPCC1183.06" ] }, "reaction_10733892": { "compartment": "compartment_7660", "id": "reaction_10733892", "reactome": "R-SPO-110218", "name": "Cleavage of uracil by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733887" ], "products": [ "species_10733889", "species_29554" ], "modifiers": [ [ "species_10733887", "catalyst" ] ], "additional_components": [ "O59825", "SPCC965.05c", "O59825", "SPCC965.05c", "O59825", "SPCC965.05c" ] }, "reaction_10733899": { "compartment": "compartment_7660", "id": "reaction_10733899", "reactome": "R-SPO-110219", "name": "Cleavage of thymine by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733896" ], "products": [ "species_29692", "species_10733889" ], "modifiers": [ [ "species_10733896", "catalyst" ] ], "additional_components": [ "O59825", "SPCC965.05c", "O59825", "SPCC965.05c", "O59825", "SPCC965.05c" ] }, "reaction_10746388": { "compartment": "compartment_7660", "id": "reaction_10746388", "reactome": "R-SPO-5651805", "name": "LIG1 bound to APEX1 and PCNA ligates SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734058" ], "products": [ "species_10746385" ], "modifiers": [ [ "species_10734058", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01" ] }, "reaction_10733929": { "compartment": "compartment_7660", "id": "reaction_10733929", "reactome": "R-SPO-110229", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733926" ], "products": [ "species_5637659", "species_10733905" ], "modifiers": [ [ "species_10733926", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10733908": { "compartment": "compartment_7660", "id": "reaction_10733908", "reactome": "R-SPO-110224", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733903" ], "products": [ "species_110223", "species_10733905" ], "modifiers": [ [ "species_10733903", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10733915": { "compartment": "compartment_7660", "id": "reaction_10733915", "reactome": "R-SPO-110226", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733912" ], "products": [ "species_10733905", "species_110225" ], "modifiers": [ [ "species_10733912", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10733952": { "compartment": "compartment_7660", "id": "reaction_10733952", "reactome": "R-SPO-110246", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733947" ], "products": [ "species_10733949", "species_5635947" ], "modifiers": [ [ "species_10733947", "catalyst" ] ], "additional_components": [ "Q10159", "SPAC26A3.02", "Q10159", "SPAC26A3.02", "Q10159", "SPAC26A3.02" ] }, "reaction_10733878": { "compartment": "compartment_7660", "id": "reaction_10733878", "reactome": "R-SPO-110215", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733871" ], "products": [ "species_29554", "species_10733875" ], "modifiers": [ [ "species_10733871", "catalyst" ] ], "additional_components": [ "O74834", "SPCC1183.06", "O74834", "SPCC1183.06", "O74834", "SPCC1183.06" ] }, "reaction_10733922": { "compartment": "compartment_7660", "id": "reaction_10733922", "reactome": "R-SPO-110227", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733919" ], "products": [ "species_30140", "species_10733905" ], "modifiers": [ [ "species_10733919", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10734060": { "compartment": "compartment_7660", "id": "reaction_10734060", "reactome": "R-SPO-110371", "name": "LIG1 binds APEX1 and PCNA at SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729536", "species_10734056" ], "products": [ "species_10734058" ], "modifiers": [], "additional_components": [ "SPAC20G8.01", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01" ] }, "reaction_10735879": { "compartment": "compartment_984", "id": "reaction_10735879", "reactome": "R-SPO-189053", "name": "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189108", "species_109276" ], "products": [ "species_70115", "species_191103", "species_188986" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10736054": { "compartment": "compartment_984", "id": "reaction_10736054", "reactome": "R-SPO-191116", "name": "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191103", "species_109276" ], "products": [ "species_70115", "species_188986" ], "modifiers": [ [ "species_10735886", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c" ] }, "reaction_10736052": { "compartment": "compartment_984", "id": "reaction_10736052", "reactome": "R-SPO-191108", "name": "maltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188986", "species_109276" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10735882": { "compartment": "compartment_984", "id": "reaction_10735882", "reactome": "R-SPO-189069", "name": "sucrose + H2O => glucose + fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188980" ], "products": [ "species_70115", "species_189049" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10735889": { "compartment": "compartment_984", "id": "reaction_10735889", "reactome": "R-SPO-189102", "name": "maltose + H2O => 2 D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188986", "species_109276" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10735886", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c" ] }, "reaction_10746655": { "compartment": "compartment_984", "id": "reaction_10746655", "reactome": "R-SPO-5659861", "name": "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_5659875" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10736050": { "compartment": "compartment_984", "id": "reaction_10736050", "reactome": "R-SPO-191101", "name": "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191103", "species_109276" ], "products": [ "species_70115", "species_188986" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10728699": { "compartment": "compartment_7660", "id": "reaction_10728699", "reactome": "R-SPO-68611", "name": "Formation of ORC(1-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728693", "species_10728682" ], "products": [ "species_10728697" ], "modifiers": [], "additional_components": [ "P54789", "SPBC29A10.15", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15" ] }, "reaction_10758124": { "compartment": "compartment_7660", "id": "reaction_10758124", "reactome": "R-SPO-9757258", "name": "MCM2 binds MCM4:MCM6:MCM7 heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728828", "species_10728845" ], "products": [ "species_10728847" ], "modifiers": [], "additional_components": [ "SPBC4.04c", "P29458", "SPCC16A11.17", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "P29458", "SPCC16A11.17", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10758076": { "compartment": "compartment_7660", "id": "reaction_10758076", "reactome": "R-SPO-9749197", "name": "ORC1 binds to H4K20me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728689", "species_10758072" ], "products": [ "species_10758074" ], "modifiers": [], "additional_components": [ "SPBC29A10.15", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P54789", "SPBC29A10.15", "P04909", "SPCC622.08c" ] }, "reaction_10758120": { "compartment": "compartment_7660", "id": "reaction_10758120", "reactome": "R-SPO-9757256", "name": "MCM3 binds MCM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728857", "species_10728852" ], "products": [ "species_10728859" ], "modifiers": [], "additional_components": [ "SPAC1B2.05", "SPCC1682.02c", "P41389", "SPAC1B2.05", "P30666", "SPCC1682.02c" ] }, "reaction_10728666": { "compartment": "compartment_7660", "id": "reaction_10728666", "reactome": "R-SPO-68595", "name": "ORC2 binds ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728657", "species_10728662" ], "products": [ "species_10728664" ], "modifiers": [], "additional_components": [ "SPBC685.09", "SPAC3H1.01c", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09" ] }, "reaction_10758078": { "compartment": "compartment_7660", "id": "reaction_10758078", "reactome": "R-SPO-9749253", "name": "Formation of MCM2-7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728847", "species_10728859" ], "products": [ "species_10728861" ], "modifiers": [], "additional_components": [ "P29458", "SPCC16A11.17", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "P41389", "SPAC1B2.05", "P30666", "SPCC1682.02c", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10758051": { "compartment": "compartment_70101", "id": "reaction_10758051", "reactome": "R-SPO-9734713", "name": "ORC6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758033" ], "products": [ "species_10728705", "species_10758049" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12", "SPBC2A9.12", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c" ] }, "reaction_10758122": { "compartment": "compartment_7660", "id": "reaction_10758122", "reactome": "R-SPO-9757257", "name": "MCM4, MCM6 and MCM7 form a heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728843", "species_10728838", "species_10728833" ], "products": [ "species_10728845" ], "modifiers": [], "additional_components": [ "SPBC25D12.03c", "SPBC211.04c", "SPCC16A11.17", "P29458", "SPCC16A11.17", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10758029": { "compartment": "compartment_70101", "id": "reaction_10758029", "reactome": "R-SPO-9734670", "name": "ORC6 binds KPNA1 or KPNA6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758023", "species_10758025" ], "products": [ "species_10758027" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "SPBC2A9.12", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12" ] }, "reaction_10758055": { "compartment": "compartment_70101", "id": "reaction_10758055", "reactome": "R-SPO-9734730", "name": "ORC1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758053" ], "products": [ "species_10728689" ], "modifiers": [], "additional_components": [ "SPBC29A10.15", "SPBC29A10.15" ] }, "reaction_10728675": { "compartment": "compartment_7660", "id": "reaction_10728675", "reactome": "R-SPO-68603", "name": "ORC5 binds ORC2:ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728671", "species_10728664" ], "products": [ "species_10728673" ], "modifiers": [], "additional_components": [ "SPBC646.14c", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09" ] }, "reaction_10728684": { "compartment": "compartment_7660", "id": "reaction_10728684", "reactome": "R-SPO-68610", "name": "Formation of ORC(2-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728680", "species_10728673" ], "products": [ "species_10728682" ], "modifiers": [ [ "species_29358", "catalyst" ] ], "additional_components": [ "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09" ] }, "reaction_10728718": { "compartment": "compartment_7660", "id": "reaction_10728718", "reactome": "R-SPO-68688", "name": "CDC6 association with ORC(1-6) at replication origins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728714", "species_10728707" ], "products": [ "species_10728716" ], "modifiers": [], "additional_components": [ "SPBC14C8.07c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15", "O74796", "SPBC2A9.12", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P41411", "SPBC14C8.07c", "P54789", "SPBC29A10.15", "O74796", "SPBC2A9.12" ] }, "reaction_10758035": { "compartment": "compartment_70101", "id": "reaction_10758035", "reactome": "R-SPO-9734687", "name": "ORC6 is phosphorylated on T195", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758027", "species_113592" ], "products": [ "species_29370", "species_10758033" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12" ] }, "reaction_10728709": { "compartment": "compartment_7660", "id": "reaction_10728709", "reactome": "R-SPO-68615", "name": "Formation of ORC(1-6) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728705", "species_10728697" ], "products": [ "species_10728707" ], "modifiers": [], "additional_components": [ "SPBC2A9.12", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15", "O74796", "SPBC2A9.12" ] }, "reaction_10747495": { "compartment": "compartment_7660", "id": "reaction_10747495", "reactome": "R-SPO-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747490" ], "products": [ "species_113582", "species_10729617" ], "modifiers": [ [ "species_10747490", "catalyst" ] ], "additional_components": [ "Q10292", "SPAC14C4.03", "SPAC14C4.03", "Q10292", "SPAC14C4.03" ] }, "reaction_10747492": { "compartment": "compartment_7660", "id": "reaction_10747492", "reactome": "R-SPO-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747488" ], "products": [ "species_10747490" ], "modifiers": [], "additional_components": [ "SPAC14C4.03", "Q10292", "SPAC14C4.03" ] }, "reaction_10734987": { "compartment": "compartment_7660", "id": "reaction_10734987", "reactome": "R-SPO-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10733361" ], "modifiers": [], "additional_components": [ "SPAC1851.02" ] }, "reaction_10734985": { "compartment": "compartment_7660", "id": "reaction_10734985", "reactome": "R-SPO-163743", "name": "Transcriptional activation of Acetyl-CoA carboxylase by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10734983" ], "modifiers": [], "additional_components": [ "SPAC56E4.04c" ] }, "reaction_10734565": { "compartment": "compartment_70101", "id": "reaction_10734565", "reactome": "R-SPO-114684", "name": "Phosphorylation of Syntaxin-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734560" ], "products": [ "species_29370", "species_10734563" ], "modifiers": [ [ "species_10734542", "catalyst" ] ], "additional_components": [ "SPCC825.03c", "SPCC825.03c", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10734555": { "compartment": "compartment_70101", "id": "reaction_10734555", "reactome": "R-SPO-114683", "name": "Phosphorylation of Platelet Sec-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734549" ], "products": [ "species_29370", "species_10734552" ], "modifiers": [ [ "species_10734542", "catalyst" ] ], "additional_components": [ "SPCC584.05", "SPCC584.05", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10735552": { "compartment": "compartment_70101", "id": "reaction_10735552", "reactome": "R-SPO-174389", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174370", "species_113592" ], "products": [ "species_158471", "species_29370" ], "modifiers": [ [ "species_10735547", "catalyst" ] ], "additional_components": [ "SPAC1782.11" ] }, "reaction_10735571": { "compartment": "compartment_70101", "id": "reaction_10735571", "reactome": "R-SPO-174392", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174375", "species_113592" ], "products": [ "species_174370", "species_111294" ], "modifiers": [ [ "species_10735547", "catalyst" ] ], "additional_components": [ "SPAC1782.11" ] }, "reaction_10743381": { "compartment": "compartment_70101", "id": "reaction_10743381", "reactome": "R-SPO-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10743369" ], "products": [ "species_10743379", "species_29372" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13", "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13" ] }, "reaction_10743406": { "compartment": "compartment_70101", "id": "reaction_10743406", "reactome": "R-SPO-2529020", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743379", "species_113592" ], "products": [ "species_29370", "species_10743369" ], "modifiers": [ [ "species_10743403", "catalyst" ] ], "additional_components": [ "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13", "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11" ] }, "reaction_10733244": { "compartment": "compartment_7660", "id": "reaction_10733244", "reactome": "R-SPO-75172", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733240", "species_10733235" ], "products": [ "species_10733242" ], "modifiers": [], "additional_components": [ "SPAC13C5.07", "SPAC1556.01c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c" ] }, "reaction_10749600": { "compartment": "compartment_7660", "id": "reaction_10749600", "reactome": "R-SPO-5693540", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747252", "species_29358" ], "products": [ "species_10737781", "species_113582", "species_10749597" ], "modifiers": [ [ "species_10747252", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "SPCC23B6.03c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747255": { "compartment": "compartment_7660", "id": "reaction_10747255", "reactome": "R-SPO-5682044", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747250", "species_113560" ], "products": [ "species_2485002", "species_10747252" ], "modifiers": [ [ "species_10747250", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747567": { "compartment": "compartment_7660", "id": "reaction_10747567", "reactome": "R-SPO-5684006", "name": "KPNA2 translocates NBN to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747559" ], "products": [ "species_10747565", "species_10733249" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O43070", "SPBC6B1.09c", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "SPBC6B1.09c" ] }, "reaction_10733253": { "compartment": "compartment_7660", "id": "reaction_10733253", "reactome": "R-SPO-75174", "name": "Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733242", "species_10733249" ], "products": [ "species_10733251" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747569": { "compartment": "compartment_70101", "id": "reaction_10747569", "reactome": "R-SPO-5684008", "name": "NBN binds KPNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747555", "species_10747557" ], "products": [ "species_10747559" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "SPBC6B1.09c", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744580": { "compartment": "compartment_7660", "id": "reaction_10744580", "reactome": "R-SPO-3785768", "name": "MRN complex binds DNA double strand breaks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733251", "species_75165" ], "products": [ "species_10744578" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10749630": { "compartment": "compartment_7660", "id": "reaction_10749630", "reactome": "R-SPO-5693612", "name": "MRN complex bound to DNA ends recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747231", "species_10744578" ], "products": [ "species_10747250" ], "modifiers": [], "additional_components": [ "Q10325", "SPAC17G8.13c", "O74630", "SPCC23B6.03c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10730078": { "compartment": "compartment_5460", "id": "reaction_10730078", "reactome": "R-SPO-70938", "name": "lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113600", "species_29444", "species_113529" ], "products": [ "species_113563", "species_113521", "species_30176" ], "modifiers": [ [ "species_10730075", "catalyst" ] ], "additional_components": [ "O59711", "SPBC3B8.03" ] }, "reaction_10730211": { "compartment": "compartment_5460", "id": "reaction_10730211", "reactome": "R-SPO-71037", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_70951" ], "products": [ "species_70955", "species_29376", "species_29362" ], "modifiers": [ [ "species_10730208", "catalyst" ] ], "additional_components": [ "O94681", "SPBC776.15c", "species_29480", "O00087", "SPAC1002.09c", "CHEBI:17460", "O74378", "SPBC3H7.03c", "species_113596" ] }, "reaction_10730081": { "compartment": "compartment_5460", "id": "reaction_10730081", "reactome": "R-SPO-70940", "name": "saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_30176" ], "products": [ "species_113556", "species_113552", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730075", "catalyst" ] ], "additional_components": [ "O59711", "SPBC3B8.03" ] }, "reaction_10750324": { "compartment": "compartment_17951", "id": "reaction_10750324", "reactome": "R-SPO-6783880", "name": "PIPOX oxidises PPCA to P6C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693325", "species_113535" ], "products": [ "species_6783877", "species_113575" ], "modifiers": [ [ "species_10750321", "catalyst" ] ], "additional_components": [ "SPBC354.15" ] }, "reaction_10753848": { "compartment": "compartment_984", "id": "reaction_10753848", "reactome": "R-SPO-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851462", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851461" ], "modifiers": [ [ "species_10753845", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58280", "species_110094", "species_110096", "species_109395", "species_29602", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753831": { "compartment": "compartment_17963", "id": "reaction_10753831", "reactome": "R-SPO-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851227", "species_425969", "species_8851226" ], "modifiers": [ [ "species_10753828", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "species_110094", "species_110096", "species_109366", "species_109395", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c" ] }, "reaction_10753786": { "compartment": "compartment_876", "id": "reaction_10753786", "reactome": "R-SPO-8850854", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753780", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753824": { "compartment": "compartment_984", "id": "reaction_10753824", "reactome": "R-SPO-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753818", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753834": { "compartment": "compartment_17963", "id": "reaction_10753834", "reactome": "R-SPO-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851233", "species_2022884" ], "products": [ "species_425969", "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10753828", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "species_110094", "species_110096", "species_74016", "Q9USP2", "SPCC11E10.05c" ] }, "reaction_10753821": { "compartment": "compartment_984", "id": "reaction_10753821", "reactome": "R-SPO-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753818", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753855": { "compartment": "compartment_528865", "id": "reaction_10753855", "reactome": "R-SPO-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851509", "species_8851517" ], "products": [ "species_8851518", "species_8851513", "species_5228597" ], "modifiers": [ [ "species_10753852", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110614", "species_29420", "species_110096", "species_110094", "species_74016", "Q9USP2", "SPCC11E10.05c" ] }, "reaction_10753783": { "compartment": "compartment_984", "id": "reaction_10753783", "reactome": "R-SPO-8850846", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753780", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753857": { "compartment": "compartment_984", "id": "reaction_10753857", "reactome": "R-SPO-8851538", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726184", "species_109276" ], "products": [ "species_9726189", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753811", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753841": { "compartment": "compartment_984", "id": "reaction_10753841", "reactome": "R-SPO-8851356", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936165", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851369" ], "modifiers": [ [ "species_10753838", "catalyst" ] ], "additional_components": [ "species_29420", "species_29370", "species_110094", "species_110096", "species_109395", "species_76577", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753814": { "compartment": "compartment_984", "id": "reaction_10753814", "reactome": "R-SPO-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8936166" ], "products": [ "species_109277", "species_351626", "species_8851092" ], "modifiers": [ [ "species_10753811", "catalyst" ] ], "additional_components": [ "species_29494", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753860": { "compartment": "compartment_984", "id": "reaction_10753860", "reactome": "R-SPO-8851550", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726189", "species_109276" ], "products": [ "species_109277", "species_351626", "species_9726186" ], "modifiers": [ [ "species_10753811", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_109366", "species_109395", "species_29602", "species_76577", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10746363": { "compartment": "compartment_13949", "id": "reaction_10746363", "reactome": "R-SPO-5638014", "name": "RAB11A:GTP-containing Golgi vesicles recruit RAB3IP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746359", "species_10746347" ], "products": [ "species_10746361" ], "modifiers": [], "additional_components": [ "O13930", "SPAC23C4.10", "C6Y4C9", "SPCC1183.12", "P17610", "SPAC18G6.03", "species_29438", "P17610", "SPAC18G6.03", "O13930", "SPAC23C4.10", "C6Y4C9", "SPCC1183.12", "species_29438" ] }, "reaction_10756951": { "compartment": "compartment_70101", "id": "reaction_10756951", "reactome": "R-SPO-9018814", "name": "RHOT1 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756946", "species_29356" ], "products": [ "species_10756948", "species_29372" ], "modifiers": [ [ "species_10756946", "catalyst" ] ], "additional_components": [ "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "species_29420", "O59781", "SPCC320.04c", "species_29438" ] }, "reaction_10756961": { "compartment": "compartment_17906", "id": "reaction_10756961", "reactome": "R-SPO-9018815", "name": "RHOT1 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756957", "species_10756946" ], "products": [ "species_10756959" ], "modifiers": [], "additional_components": [ "O74805", "SPBC2D10.14c", "O94477", "SPCC1919.10c", "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "O74805", "SPBC2D10.14c", "species_29438", "O94477", "SPCC1919.10c" ] }, "reaction_10746671": { "compartment": "compartment_70101", "id": "reaction_10746671", "reactome": "R-SPO-5662471", "name": "SORD tetramer oxidizes xylitol to D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5660033", "species_29360" ], "products": [ "species_70106", "species_73473", "species_5661281" ], "modifiers": [ [ "species_10746446", "catalyst" ] ], "additional_components": [ "species_442320", "P36624", "SPBC1773.05c" ] }, "reaction_10746668": { "compartment": "compartment_70101", "id": "reaction_10746668", "reactome": "R-SPO-5662466", "name": "XYLB phosphorylates D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5661281", "species_113592" ], "products": [ "species_29370", "species_29790" ], "modifiers": [ [ "species_10746665", "catalyst" ] ], "additional_components": [ "SPCPJ732.02c" ] }, "reaction_10746139": { "compartment": "compartment_70101", "id": "reaction_10746139", "reactome": "R-SPO-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10746137" ], "products": [ "species_10746135", "species_29420" ], "modifiers": [ [ "species_10737885", "catalyst" ] ], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "P36579", "SPBC4F6.18c", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10745780": { "compartment": "compartment_7660", "id": "reaction_10745780", "reactome": "R-SPO-5358513", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358527", "species_10745776" ], "products": [ "species_10745778" ], "modifiers": [], "additional_components": [ "P26359", "SPAC8F11.03", "O74773", "SPBC19G7.01c", "species_29370", "P26359", "SPAC8F11.03", "O74773", "SPBC19G7.01c", "species_29370" ] }, "reaction_10750285": { "compartment": "compartment_7660", "id": "reaction_10750285", "reactome": "R-SPO-6782227", "name": "Ligation of newly synthesized repair patch to incised DNA in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750271" ], "products": [ "species_10749293", "species_10750283" ], "modifiers": [ [ "species_10729536", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "SPAC20G8.01" ] }, "reaction_10746607": { "compartment": "compartment_7660", "id": "reaction_10746607", "reactome": "R-SPO-5655835", "name": "POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746599", "species_10746603", "species_10733995", "species_10733957" ], "products": [ "species_10746605" ], "modifiers": [], "additional_components": [ "O74944", "SPCC553.07c", "species_113527", "species_29926", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "SPBC1347.01c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "Q0E7J8", "SPBC12D12.09", "P0C8R3", "SPAC589.10c", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746433": { "compartment": "compartment_7660", "id": "reaction_10746433", "reactome": "R-SPO-5652009", "name": "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746426", "species_10729044" ], "products": [ "species_10746430", "species_10734037", "species_10746424" ], "modifiers": [ [ "species_10746426", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "Q10990", "SPAC17H9.19c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "Q10990", "SPAC17H9.19c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "Q10990", "SPAC17H9.19c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10745785": { "compartment": "compartment_7660", "id": "reaction_10745785", "reactome": "R-SPO-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745767" ], "products": [ "species_10745782" ], "modifiers": [ [ "species_10745767", "catalyst" ] ], "additional_components": [ "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10749595": { "compartment": "compartment_7660", "id": "reaction_10749595", "reactome": "R-SPO-5693536", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10749592" ], "products": [ "species_113582", "species_10747437" ], "modifiers": [ [ "species_10749592", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10745797": { "compartment": "compartment_7660", "id": "reaction_10745797", "reactome": "R-SPO-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358610", "species_29358" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10729536", "catalyst" ] ], "additional_components": [ "SPAC20G8.01" ] }, "reaction_10747479": { "compartment": "compartment_7660", "id": "reaction_10747479", "reactome": "R-SPO-5683405", "name": "PPP5C dephosphorylates TP53BP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747469" ], "products": [ "species_113550", "species_10747471" ], "modifiers": [ [ "species_10747476", "catalyst" ] ], "additional_components": [ "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P87074", "SPBC342.05", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c", "SPBC3F6.01c" ] }, "reaction_10750503": { "compartment": "compartment_7660", "id": "reaction_10750503", "reactome": "R-SPO-6790454", "name": "SUMOylation of XPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749477", "species_10750487" ], "products": [ "species_10743639", "species_10750496" ], "modifiers": [ [ "species_10750500", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "Q9HDW3", "SPBC32F12.15", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O13351", "SPBC365.06", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O94451", "SPAC1687.05" ] }, "reaction_10733974": { "compartment": "compartment_7660", "id": "reaction_10733974", "reactome": "R-SPO-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733970", "species_10733957" ], "products": [ "species_10733972" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC1347.01c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746644": { "compartment": "compartment_7660", "id": "reaction_10746644", "reactome": "R-SPO-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10746635" ], "products": [ "species_10746641", "species_113541" ], "modifiers": [ [ "species_10746635", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749297": { "compartment": "compartment_7660", "id": "reaction_10749297", "reactome": "R-SPO-5690213", "name": "DNA polymerases delta, epsilon or kappa bind the GG-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749283", "species_10749285", "species_10749281", "species_10729448" ], "products": [ "species_10749295" ], "modifiers": [], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "O74944", "SPCC553.07c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P36617", "SPCC970.01", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P28706", "SPBC3E7.08c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "O74366", "SPBC30B4.07c" ] }, "reaction_10745941": { "compartment": "compartment_7660", "id": "reaction_10745941", "reactome": "R-SPO-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745744", "species_10745749" ], "products": [ "species_10745751" ], "modifiers": [], "additional_components": [ "SPBC1703.04", "SPAC19G12.02c", "P54280", "SPAC19G12.02c", "Q9P7W6", "SPBC1703.04" ] }, "reaction_10747451": { "compartment": "compartment_7660", "id": "reaction_10747451", "reactome": "R-SPO-5682983", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747446" ], "products": [ "species_113582", "species_10747439" ], "modifiers": [ [ "species_10747446", "catalyst" ] ], "additional_components": [ "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10747379": { "compartment": "compartment_7660", "id": "reaction_10747379", "reactome": "R-SPO-5682629", "name": "HERC2 facilitates UBE2N:UBE2V2 binding to RNF8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747364", "species_10747373" ], "products": [ "species_10747377" ], "modifiers": [], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c" ] }, "reaction_10745795": { "compartment": "compartment_7660", "id": "reaction_10745795", "reactome": "R-SPO-5358579", "name": "DNA polymerase delta polymerizes DNA across single stranded gap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_30187", "species_29604", "species_29892", "species_10745793" ], "products": [ "species_5358610", "species_10729504" ], "modifiers": [ [ "species_10729489", "catalyst" ] ], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04" ] }, "reaction_10749612": { "compartment": "compartment_7660", "id": "reaction_10749612", "reactome": "R-SPO-5693598", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749597", "species_29358" ], "products": [ "species_113582", "species_10747312" ], "modifiers": [ [ "species_10749597", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10745791": { "compartment": "compartment_7660", "id": "reaction_10745791", "reactome": "R-SPO-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358514", "species_10745787" ], "products": [ "species_10745789" ], "modifiers": [], "additional_components": [ "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c", "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c" ] }, "reaction_10746625": { "compartment": "compartment_7660", "id": "reaction_10746625", "reactome": "R-SPO-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746613", "species_30555" ], "products": [ "species_113541", "species_10733995", "species_10733957", "species_10746622" ], "modifiers": [ [ "species_10746613", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "SPBC1347.01c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746590": { "compartment": "compartment_7660", "id": "reaction_10746590", "reactome": "R-SPO-5655481", "name": "USP1:WDR48 binds monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746430", "species_10746581" ], "products": [ "species_10746583" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q09731", "SPAC31A2.14", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10749487": { "compartment": "compartment_7660", "id": "reaction_10749487", "reactome": "R-SPO-5691001", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10749464" ], "products": [ "species_10749484", "species_113541" ], "modifiers": [ [ "species_10749464", "catalyst" ] ], "additional_components": [ "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04" ] }, "reaction_10750274": { "compartment": "compartment_7660", "id": "reaction_10750274", "reactome": "R-SPO-6782208", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750269", "species_30555" ], "products": [ "species_113541", "species_10750271" ], "modifiers": [ [ "species_10750269", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c" ] }, "reaction_10745769": { "compartment": "compartment_7660", "id": "reaction_10745769", "reactome": "R-SPO-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729459", "species_10745751", "species_10745765" ], "products": [ "species_10745767" ], "modifiers": [], "additional_components": [ "Q03392", "SPBC16D10.09", "P54280", "SPAC19G12.02c", "Q9P7W6", "SPBC1703.04", "O74773", "SPBC19G7.01c", "species_113592", "O74502", "SPCC285.16c", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10745937": { "compartment": "compartment_7660", "id": "reaction_10745937", "reactome": "R-SPO-5444511", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10745756", "species_10745774" ], "products": [ "species_10745776" ], "modifiers": [], "additional_components": [ "SPBC19G7.01c", "SPAC8F11.03", "P26359", "SPAC8F11.03", "O74773", "SPBC19G7.01c", "species_29370" ] }, "reaction_10749480": { "compartment": "compartment_7660", "id": "reaction_10749480", "reactome": "R-SPO-5690996", "name": "ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10749473" ], "products": [ "species_113582", "species_113550", "species_10749477" ], "modifiers": [ [ "species_10749473", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O13807", "SPAC17H9.10c", "Q9HDW3", "SPBC32F12.15", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10747448": { "compartment": "compartment_7660", "id": "reaction_10747448", "reactome": "R-SPO-5682967", "name": "WHSC1 binds DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747437", "species_10747441" ], "products": [ "species_10747446" ], "modifiers": [], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "SPAC29B12.02c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10749607": { "compartment": "compartment_7660", "id": "reaction_10749607", "reactome": "R-SPO-5693566", "name": "TP53BP1 associates with H4K20Me2 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743694", "species_10747455" ], "products": [ "species_10747471" ], "modifiers": [], "additional_components": [ "SPBC342.05", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c" ] }, "reaction_10746597": { "compartment": "compartment_7660", "id": "reaction_10746597", "reactome": "R-SPO-5655483", "name": "USP1 autocleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746581" ], "products": [ "species_10746592", "species_10746579", "species_10746594" ], "modifiers": [ [ "species_10746581", "catalyst" ] ], "additional_components": [ "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "SPBC1703.12", "SPAC31A2.14", "SPBC1703.12", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10734004": { "compartment": "compartment_7660", "id": "reaction_10734004", "reactome": "R-SPO-110311", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10733997" ], "products": [ "species_10734001", "species_113541", "species_10733995" ], "modifiers": [ [ "species_10733997", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749469": { "compartment": "compartment_7660", "id": "reaction_10749469", "reactome": "R-SPO-5690990", "name": "5'- incision of DNA by ERCC1:ERCC4 in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749466" ], "products": [ "species_10749281" ], "modifiers": [ [ "species_10749466", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c" ] }, "reaction_10747367": { "compartment": "compartment_7660", "id": "reaction_10747367", "reactome": "R-SPO-5682607", "name": "PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747350", "species_10743647" ], "products": [ "species_10743639", "species_10747364" ], "modifiers": [ [ "species_10747350", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c" ] }, "reaction_10747463": { "compartment": "compartment_7660", "id": "reaction_10747463", "reactome": "R-SPO-5683077", "name": "RNF8 and RNF168 ubiquitinate KDM4A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747420", "species_10729044" ], "products": [ "species_10747458", "species_10747455" ], "modifiers": [ [ "species_10747420", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O94691", "SPBC83.07", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC83.07", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O94691", "SPBC83.07", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c" ] }, "reaction_10747353": { "compartment": "compartment_7660", "id": "reaction_10747353", "reactome": "R-SPO-5682598", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747346" ], "products": [ "species_113582", "species_10747350" ], "modifiers": [ [ "species_10747346", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c" ] }, "reaction_10747444": { "compartment": "compartment_7660", "id": "reaction_10747444", "reactome": "R-SPO-5682965", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747439", "species_77087" ], "products": [ "species_10747334", "species_77502" ], "modifiers": [ [ "species_10747439", "catalyst" ] ], "additional_components": [ "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10746428": { "compartment": "compartment_7660", "id": "reaction_10746428", "reactome": "R-SPO-5652005", "name": "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746424", "species_10746392" ], "products": [ "species_10746426" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "Q10990", "SPAC17H9.19c", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "Q10990", "SPAC17H9.19c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10747820": { "compartment": "compartment_7660", "id": "reaction_10747820", "reactome": "R-SPO-5689861", "name": "Recruitment of XPA and release of CAK ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747770", "species_10747816" ], "products": [ "species_10732457", "species_10747818" ], "modifiers": [], "additional_components": [ "SPBC649.03", "O13807", "SPAC17H9.10c", "P36613", "SPBP16F5.02", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74803", "SPBC2D10.12", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749628": { "compartment": "compartment_7660", "id": "reaction_10749628", "reactome": "R-SPO-5693602", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747312", "species_10747536" ], "products": [ "species_10749602" ], "modifiers": [], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10745811": { "compartment": "compartment_7660", "id": "reaction_10745811", "reactome": "R-SPO-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10745789" ], "products": [ "species_113582", "species_10745765" ], "modifiers": [], "additional_components": [ "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c", "O74773", "SPBC19G7.01c", "species_113592", "O74502", "SPCC285.16c" ] }, "reaction_10734026": { "compartment": "compartment_7660", "id": "reaction_10734026", "reactome": "R-SPO-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734015", "species_29604" ], "products": [ "species_113541", "species_10734023" ], "modifiers": [ [ "species_10734015", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10745939": { "compartment": "compartment_7660", "id": "reaction_10745939", "reactome": "R-SPO-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10745756", "species_10745761" ], "products": [ "species_10745787" ], "modifiers": [], "additional_components": [ "SPBC19G7.01c", "SPCC285.16c", "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c" ] }, "reaction_10747482": { "compartment": "compartment_7660", "id": "reaction_10747482", "reactome": "R-SPO-5683425", "name": "ATM phosphorylates TP53BP1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747471" ], "products": [ "species_113582", "species_10747469" ], "modifiers": [ [ "species_10747471", "catalyst" ] ], "additional_components": [ "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P87074", "SPBC342.05", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c" ] }, "reaction_10745806": { "compartment": "compartment_7660", "id": "reaction_10745806", "reactome": "R-SPO-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745782", "species_10745802" ], "products": [ "species_10745804" ], "modifiers": [], "additional_components": [ "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "SPBC29A10.05", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "P53695", "SPBC29A10.05" ] }, "reaction_10733831": { "compartment": "compartment_7660", "id": "reaction_10733831", "reactome": "R-SPO-109955", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733822", "species_10733827" ], "products": [ "species_10733829" ], "modifiers": [], "additional_components": [ "SPBC4F6.15c", "SPCC970.01", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c" ] }, "reaction_10734035": { "compartment": "compartment_7660", "id": "reaction_10734035", "reactome": "R-SPO-110322", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733993", "species_10733988" ], "products": [ "species_10733995" ], "modifiers": [], "additional_components": [ "SPBC12D12.09", "SPAC688.10", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10" ] }, "reaction_10745809": { "compartment": "compartment_7660", "id": "reaction_10745809", "reactome": "R-SPO-5358599", "name": "EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745804", "species_10729504" ], "products": [ "species_10745793" ], "modifiers": [ [ "species_10745804", "catalyst" ] ], "additional_components": [ "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "P53695", "SPBC29A10.05", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "P53695", "SPBC29A10.05" ] }, "reaction_10746435": { "compartment": "compartment_7660", "id": "reaction_10746435", "reactome": "R-SPO-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733995", "species_10733980" ], "products": [ "species_10733997" ], "modifiers": [], "additional_components": [ "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746653": { "compartment": "compartment_7660", "id": "reaction_10746653", "reactome": "R-SPO-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746641", "species_30555" ], "products": [ "species_10746650", "species_113541", "species_10733957", "species_10733995" ], "modifiers": [ [ "species_10746641", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC1347.01c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10734017": { "compartment": "compartment_7660", "id": "reaction_10734017", "reactome": "R-SPO-110316", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734013", "species_10734009" ], "products": [ "species_10734015" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC16A3.11", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746588": { "compartment": "compartment_7660", "id": "reaction_10746588", "reactome": "R-SPO-5655466", "name": "USP1:WDR48 deubiquitinates monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746583" ], "products": [ "species_10746581", "species_10729044", "species_10746585" ], "modifiers": [ [ "species_10746583", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q09731", "SPAC31A2.14", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9P7V9", "SPBC1703.12", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q09731", "SPAC31A2.14", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10746564": { "compartment": "compartment_7660", "id": "reaction_10746564", "reactome": "R-SPO-5654985", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746544", "species_10746560" ], "products": [ "species_10746562" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O42915", "SPBC16A3.09c", "Q9P3A7", "SPAC1565.08", "Q9P780", "SPBC1711.10c", "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10733983": { "compartment": "compartment_7660", "id": "reaction_10733983", "reactome": "R-SPO-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10733972" ], "products": [ "species_10733980" ], "modifiers": [ [ "species_10733972", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749609": { "compartment": "compartment_7660", "id": "reaction_10749609", "reactome": "R-SPO-5693583", "name": "MDC1 associates with gamma-H2AFX at nuclear foci", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747435", "species_10749590" ], "products": [ "species_10749592" ], "modifiers": [], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14079", "SPACUNK4.14", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10749471": { "compartment": "compartment_7660", "id": "reaction_10749471", "reactome": "R-SPO-5690991", "name": "Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747788", "species_10733829" ], "products": [ "species_10749466" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c" ] }, "reaction_10747423": { "compartment": "compartment_7660", "id": "reaction_10747423", "reactome": "R-SPO-5682858", "name": "RNF8 and RNF168 ubiquitinate H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747398", "species_10729044" ], "products": [ "species_10747420" ], "modifiers": [ [ "species_10747398", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O94691", "SPBC83.07", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c" ] }, "reaction_10746616": { "compartment": "compartment_7660", "id": "reaction_10746616", "reactome": "R-SPO-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746605", "species_30555" ], "products": [ "species_10746613", "species_113541" ], "modifiers": [ [ "species_10746605", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "Q0E7J8", "SPBC12D12.09", "P0C8R3", "SPAC589.10c", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "Q0E7J8", "SPBC12D12.09", "P0C8R3", "SPAC589.10c", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749977": { "compartment": "compartment_7660", "id": "reaction_10749977", "reactome": "R-SPO-5696465", "name": "USP45 deubiquitinates ERCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10749972" ], "products": [ "species_10733822", "species_10729044" ], "modifiers": [ [ "species_10749974", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q06182", "SPBC4F6.15c", "SPBC4F6.15c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPAC23G3.08c" ] }, "reaction_10734033": { "compartment": "compartment_7660", "id": "reaction_10734033", "reactome": "R-SPO-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10734023" ], "products": [ "species_10734030", "species_113541" ], "modifiers": [ [ "species_10734023", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746569": { "compartment": "compartment_7660", "id": "reaction_10746569", "reactome": "R-SPO-5654989", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746562", "species_29358" ], "products": [ "species_113582", "species_10746566", "species_10734009" ], "modifiers": [ [ "species_10746562", "catalyst" ] ], "additional_components": [ "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC16A3.11", "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10747453": { "compartment": "compartment_7660", "id": "reaction_10747453", "reactome": "R-SPO-5682992", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747336", "species_10747334" ], "products": [ "species_10747340" ], "modifiers": [], "additional_components": [ "SPBC83.07", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10747790": { "compartment": "compartment_7660", "id": "reaction_10747790", "reactome": "R-SPO-5689317", "name": "Formation of the pre-incision complex in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747786", "species_10747765", "species_10729504" ], "products": [ "species_10747788" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13768", "SPAC17A5.06", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P26659", "SPAC1D4.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "O74995", "SPCC1682.07", "SPBC3E7.08c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c" ] }, "reaction_10749605": { "compartment": "compartment_7660", "id": "reaction_10749605", "reactome": "R-SPO-5693549", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10749602" ], "products": [ "species_113582", "species_10747546" ], "modifiers": [ [ "species_10749602", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10743005": { "compartment": "compartment_5460", "id": "reaction_10743005", "reactome": "R-SPO-2162253", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162256", "species_2162257" ], "products": [ "species_2162214", "species_159450" ], "modifiers": [ [ "species_10743002", "catalyst" ] ], "additional_components": [ "O13851", "SPAC19G12.12", "species_29926", "O43091", "SPBPJ4664.01" ] }, "reaction_10742984": { "compartment": "compartment_5460", "id": "reaction_10742984", "reactome": "R-SPO-2162193", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162209", "species_2162265" ], "products": [ "species_2162252", "species_2162215", "species_113529" ], "modifiers": [ [ "species_10742970", "catalyst" ] ], "additional_components": [ "SPCC162.05" ] }, "reaction_10742973": { "compartment": "compartment_5460", "id": "reaction_10742973", "reactome": "R-SPO-2162186", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162212", "species_2162265" ], "products": [ "species_2162252", "species_2162198", "species_113529" ], "modifiers": [ [ "species_10742970", "catalyst" ] ], "additional_components": [ "SPCC162.05" ] }, "reaction_10742981": { "compartment": "compartment_70616", "id": "reaction_10742981", "reactome": "R-SPO-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10742978", "catalyst" ] ], "additional_components": [ "SPBC3F6.01c" ] }, "reaction_10734456": { "compartment": "compartment_7660", "id": "reaction_10734456", "reactome": "R-SPO-112430", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734280", "species_10734258" ], "products": [ "species_10734282" ], "modifiers": [], "additional_components": [ "O74627", "SPBC32F12.06", "O59748", "SPBC530.13", "SPAC2F3.15", "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15", "O59748", "SPBC530.13" ] }, "reaction_10734442": { "compartment": "compartment_7660", "id": "reaction_10734442", "reactome": "R-SPO-112392", "name": "Resumption of elongation after recovery from pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734440" ], "products": [ "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734458": { "compartment": "compartment_7660", "id": "reaction_10734458", "reactome": "R-SPO-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733600", "species_10734297" ], "products": [ "species_10734299" ], "modifiers": [], "additional_components": [ "SPAC23C4.19", "SPBC21C3.16c", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19" ] }, "reaction_10733342": { "compartment": "compartment_7660", "id": "reaction_10733342", "reactome": "R-SPO-75862", "name": "Fall Back to Closed Pre-initiation Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733332" ], "products": [ "species_10733340" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10734468": { "compartment": "compartment_7660", "id": "reaction_10734468", "reactome": "R-SPO-113413", "name": "TFIIS-mediated recovery of elongation from arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734454": { "compartment": "compartment_7660", "id": "reaction_10734454", "reactome": "R-SPO-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734357", "species_10734352" ], "products": [ "species_10734359" ], "modifiers": [], "additional_components": [ "SPBP8B7.19", "SPBC609.05", "O94529", "SPBC609.05", "O94267", "SPBP8B7.19" ] }, "reaction_10734462": { "compartment": "compartment_7660", "id": "reaction_10734462", "reactome": "R-SPO-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734367" ], "products": [ "species_10734367" ], "modifiers": [], "additional_components": [ "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13936", "SPAC23C4.19", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13936", "SPAC23C4.19", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10732715": { "compartment": "compartment_7660", "id": "reaction_10732715", "reactome": "R-SPO-73946", "name": "Abortive initiation after formation of the first phosphodiester bond", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732713" ], "products": [ "species_109877", "species_10732699", "species_10732619", "species_10732494", "species_10732624", "species_10732711", "species_10730708" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "SPAC16E8.16", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10733330": { "compartment": "compartment_7660", "id": "reaction_10733330", "reactome": "R-SPO-75856", "name": "Abortive Initiation Before Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733328" ], "products": [ "species_110068", "species_10732699", "species_10732619", "species_10732494", "species_10732624", "species_10732711", "species_10730708" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "SPAC16E8.16", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10734446": { "compartment": "compartment_7660", "id": "reaction_10734446", "reactome": "R-SPO-112395", "name": "Abortive termination of elongation after arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734444" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734464": { "compartment": "compartment_7660", "id": "reaction_10734464", "reactome": "R-SPO-113411", "name": "2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734440" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734470": { "compartment": "compartment_7660", "id": "reaction_10734470", "reactome": "R-SPO-113414", "name": "7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10733400": { "compartment": "compartment_7660", "id": "reaction_10733400", "reactome": "R-SPO-75891", "name": "Abortive Initiation After Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733398" ], "products": [ "species_75897", "species_10732494", "species_10732711", "species_10730708" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10737527": { "compartment": "compartment_70101", "id": "reaction_10737527", "reactome": "R-SPO-209792", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183", "species_209914" ], "products": [ "species_76194", "species_209793" ], "modifiers": [ [ "species_10737524", "catalyst" ] ], "additional_components": [ "SPAC9.02c" ] }, "reaction_10741986": { "compartment": "compartment_12045", "id": "reaction_10741986", "reactome": "R-SPO-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741994": { "compartment": "compartment_12045", "id": "reaction_10741994", "reactome": "R-SPO-1482827", "name": "PC is hydrolyzed to 2-acyl LPC by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742013": { "compartment": "compartment_12045", "id": "reaction_10742013", "reactome": "R-SPO-1482862", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741810": { "compartment": "compartment_12045", "id": "reaction_10741810", "reactome": "R-SPO-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741770": { "compartment": "compartment_12045", "id": "reaction_10741770", "reactome": "R-SPO-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10742007": { "compartment": "compartment_12045", "id": "reaction_10742007", "reactome": "R-SPO-1482856", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10742004", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10738121": { "compartment": "compartment_5460", "id": "reaction_10738121", "reactome": "R-SPO-380608", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380598", "species_113526" ], "products": [ "species_380593", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730539", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10742179": { "compartment": "compartment_70101", "id": "reaction_10742179", "reactome": "R-SPO-1497796", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737053", "species_1497857" ], "products": [ "species_29870", "species_10742177" ], "modifiers": [], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "P36587", "SPBC29A10.01", "species_29870", "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_1497857", "species_29870", "P36587", "SPBC29A10.01" ] }, "reaction_10741760": { "compartment": "compartment_70101", "id": "reaction_10741760", "reactome": "R-SPO-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10741757", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ] ], "additional_components": [ "O13774", "SPAC17A5.13" ] }, "reaction_10735967": { "compartment": "compartment_5460", "id": "reaction_10735967", "reactome": "R-SPO-189465", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189487", "species_113531" ], "products": [ "species_189444", "species_113529" ], "modifiers": [ [ "species_10735964", "catalyst" ], [ "species_391232", "inhibitor" ] ], "additional_components": [ "O59786", "SPCC320.09" ] }, "reaction_10735899": { "compartment": "compartment_70101", "id": "reaction_10735899", "reactome": "R-SPO-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189464", "species_29356" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10735896", "catalyst" ] ], "additional_components": [ "CHEBI:36319", "Q09899", "SPAC24B11.13" ] }, "reaction_10747163": { "compartment": "compartment_70101", "id": "reaction_10747163", "reactome": "R-SPO-5679041", "name": "ABCC2 transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5679042", "species_29356" ], "products": [ "species_29370", "species_5679034", "species_29372" ], "modifiers": [ [ "species_10741710", "catalyst" ] ], "additional_components": [ "CHEBI:16427", "CHEBI:18392", "CHEBI:16427", "CHEBI:18392", "Q10185", "SPAC3F10.11c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10735981": { "compartment": "compartment_70101", "id": "reaction_10735981", "reactome": "R-SPO-190182", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190157" ], "products": [ "species_113528", "species_190128" ], "modifiers": [ [ "species_10735926", "catalyst" ] ], "additional_components": [ "Q9USJ5", "SPCC4B3.05c" ] }, "reaction_10735909": { "compartment": "compartment_17927", "id": "reaction_10735909", "reactome": "R-SPO-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189411", "species_189461" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10735906", "catalyst" ] ], "additional_components": [ "Q9UTE2", "SPAC222.11" ] }, "reaction_10735939": { "compartment": "compartment_70101", "id": "reaction_10735939", "reactome": "R-SPO-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_70106", "species_189464", "species_29356" ], "modifiers": [ [ "species_10735936", "catalyst" ] ], "additional_components": [ "P78974", "SPAC1805.06c", "species_442320" ] }, "reaction_10735975": { "compartment": "compartment_70101", "id": "reaction_10735975", "reactome": "R-SPO-189488", "name": "UROS transforms HMB to URO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189449" ], "products": [ "species_189407", "species_29356" ], "modifiers": [ [ "species_10735972", "catalyst" ] ], "additional_components": [ "SPAC31G5.08" ] }, "reaction_10735929": { "compartment": "compartment_70101", "id": "reaction_10735929", "reactome": "R-SPO-189425", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189407" ], "products": [ "species_113528", "species_189455" ], "modifiers": [ [ "species_10735926", "catalyst" ] ], "additional_components": [ "Q9USJ5", "SPCC4B3.05c" ] }, "reaction_10743681": { "compartment": "compartment_5460", "id": "reaction_10743681", "reactome": "R-SPO-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_2162257", "species_189444" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10743678", "catalyst" ] ], "additional_components": [ "SPBC365.02c" ] }, "reaction_10735957": { "compartment": "compartment_5460", "id": "reaction_10735957", "reactome": "R-SPO-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_159549", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10735954", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "O14092", "SPAC2F3.09" ] }, "reaction_10735979": { "compartment": "compartment_70101", "id": "reaction_10735979", "reactome": "R-SPO-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735936", "species_190173" ], "products": [ "species_29426", "species_10735977" ], "modifiers": [], "additional_components": [ "P78974", "SPAC1805.06c", "species_442320", "P78974", "SPAC1805.06c", "species_442320", "species_190173" ] }, "reaction_10735919": { "compartment": "compartment_17927", "id": "reaction_10735919", "reactome": "R-SPO-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10735916", "catalyst" ] ], "additional_components": [ "Q10062", "SPAC1F5.07c", "species_113596" ] }, "reaction_10757699": { "compartment": "compartment_70101", "id": "reaction_10757699", "reactome": "R-SPO-9661405", "name": "ABCC1 transports BIL from cytosol to extracellular region (blood)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189386" ], "products": [ "species_9661418" ], "modifiers": [ [ "species_10737726", "catalyst" ] ], "additional_components": [ "SPAC3F10.11c" ] }, "reaction_10743689": { "compartment": "compartment_5460", "id": "reaction_10743689", "reactome": "R-SPO-2995334", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2995328" ], "products": [ "species_2995348" ], "modifiers": [ [ "species_10743686", "catalyst" ] ], "additional_components": [ "SPAC22E12.10c" ] }, "reaction_10757253": { "compartment": "compartment_17947", "id": "reaction_10757253", "reactome": "R-SPO-9603784", "name": "PEX19:class I PMP binds PEX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757231", "species_10738205" ], "products": [ "species_10757233" ], "modifiers": [], "additional_components": [ "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14136", "SPAC3C7.10", "SPAC29A4.14c", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14017", "SPAC29A4.14c", "O14136", "SPAC3C7.10" ] }, "reaction_10757255": { "compartment": "compartment_70101", "id": "reaction_10757255", "reactome": "R-SPO-9603804", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757189", "species_10757229" ], "products": [ "species_10757231" ], "modifiers": [], "additional_components": [ "SPAC17C9.14", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "O14136", "SPAC3C7.10", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14136", "SPAC3C7.10" ] }, "reaction_10757251": { "compartment": "compartment_17947", "id": "reaction_10757251", "reactome": "R-SPO-9603775", "name": "PEX3:PEX19:class I PMP dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757233" ], "products": [ "species_10757189", "species_10757249", "species_10738205" ], "modifiers": [], "additional_components": [ "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14017", "SPAC29A4.14c", "O14136", "SPAC3C7.10", "SPAC17C9.14", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "O14136", "SPAC3C7.10", "SPAC29A4.14c" ] }, "reaction_10738119": { "compartment": "compartment_374932", "id": "reaction_10738119", "reactome": "R-SPO-380586", "name": "loading of Serotonin in synaptic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209914" ], "products": [ "species_380585" ], "modifiers": [ [ "species_10737993", "catalyst" ] ], "additional_components": [ "SPCC18.02" ] }, "reaction_10757333": { "compartment": "compartment_70101", "id": "reaction_10757333", "reactome": "R-SPO-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737034", "species_10757329" ], "products": [ "species_10757331" ], "modifiers": [], "additional_components": [ "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "SPACUNK12.02c", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9P7I2", "SPACUNK12.02c" ] }, "reaction_10757822": { "compartment": "compartment_876", "id": "reaction_10757822", "reactome": "R-SPO-9679775", "name": "COMT binds COMT Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9679778", "species_10738036" ], "products": [ "species_10738039" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=6646", "LigandDisplayForward?ligandId=6647", "LigandDisplayForward?ligandId=8988", "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6646", "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6647", "LigandDisplayForward?ligandId=8988" ] }, "reaction_10738044": { "compartment": "compartment_70101", "id": "reaction_10738044", "reactome": "R-SPO-379464", "name": "COMT transfers Met to DOPAC to form HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9677997", "species_71284" ], "products": [ "species_174369", "species_9677992" ], "modifiers": [ [ "species_10738036", "catalyst" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c" ] }, "reaction_10738041": { "compartment": "compartment_70101", "id": "reaction_10738041", "reactome": "R-SPO-379387", "name": "COMT transfers Met to DA to form 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159362", "species_71284" ], "products": [ "species_71285", "species_8954997" ], "modifiers": [ [ "species_10738036", "catalyst" ], [ "species_10738039", "inhibitor" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6646", "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6647", "LigandDisplayForward?ligandId=8988" ] }, "reaction_10737996": { "compartment": "compartment_374932", "id": "reaction_10737996", "reactome": "R-SPO-372542", "name": "Loading of dopamine into synaptic veiscles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159362" ], "products": [ "species_351601" ], "modifiers": [ [ "species_10737993", "catalyst" ] ], "additional_components": [ "SPCC18.02" ] }, "reaction_10757324": { "compartment": "compartment_70101", "id": "reaction_10757324", "reactome": "R-SPO-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10757317" ], "products": [ "species_29370", "species_10757321" ], "modifiers": [ [ "species_10757317", "catalyst" ] ], "additional_components": [ "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05" ] }, "reaction_10756407": { "compartment": "compartment_70101", "id": "reaction_10756407", "reactome": "R-SPO-8955010", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159362", "species_71284" ], "products": [ "species_71285", "species_8954997" ], "modifiers": [ [ "species_10756404", "catalyst" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c" ] }, "reaction_10757358": { "compartment": "compartment_876", "id": "reaction_10757358", "reactome": "R-SPO-9625814", "name": "SPHK1 phosphorylates sphingosine in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1606609" ], "products": [ "species_5218688" ], "modifiers": [ [ "species_10738404", "catalyst" ] ], "additional_components": [ "SPAC4A8.07c" ] }, "reaction_10737078": { "compartment": "compartment_20699", "id": "reaction_10737078", "reactome": "R-SPO-202132", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737066" ], "products": [ "species_10737076" ], "modifiers": [], "additional_components": [ "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_29870", "species_113596", "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_29870", "species_113596" ] }, "reaction_10737226": { "compartment": "compartment_20699", "id": "reaction_10737226", "reactome": "R-SPO-203700", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737196" ], "products": [ "species_10736995" ], "modifiers": [], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_113596" ] }, "reaction_10737204": { "compartment": "compartment_20699", "id": "reaction_10737204", "reactome": "R-SPO-203567", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737064", "species_200993" ], "products": [ "species_10737196" ], "modifiers": [ [ "species_10737201", "catalyst" ] ], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "SPBC3H7.09" ] }, "reaction_10737214": { "compartment": "compartment_70101", "id": "reaction_10737214", "reactome": "R-SPO-203611", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737212", "species_184174" ], "products": [ "species_10737064" ], "modifiers": [], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01" ] }, "reaction_10737224": { "compartment": "compartment_876", "id": "reaction_10737224", "reactome": "R-SPO-203613", "name": "depalmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736995" ], "products": [ "species_76168", "species_10737066" ], "modifiers": [ [ "species_10737221", "catalyst" ] ], "additional_components": [ "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_113596", "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_29870", "species_113596", "O42881", "SPAC8E11.04c" ] }, "reaction_10742182": { "compartment": "compartment_70101", "id": "reaction_10742182", "reactome": "R-SPO-1497810", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29368" ], "products": [ "species_29366", "species_1222424" ], "modifiers": [ [ "species_10742177", "catalyst" ] ], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_1497857", "species_29870", "P36587", "SPBC29A10.01" ] }, "reaction_10740054": { "compartment": "compartment_876", "id": "reaction_10740054", "reactome": "R-SPO-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740042" ], "products": [ "species_10740052" ], "modifiers": [], "additional_components": [ "O74557", "SPCC970.03", "O13809", "SPAC17H9.12c", "P87178", "SPBC3D6.13c", "O74557", "SPCC970.03", "O13809", "SPAC17H9.12c", "P87178", "SPBC3D6.13c" ] }, "reaction_10734544": { "compartment": "compartment_70101", "id": "reaction_10734544", "reactome": "R-SPO-114553", "name": "Activation of conventional Protein Kinase C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734522", "species_74016", "species_33625", "species_114519" ], "products": [ "species_10734542" ], "modifiers": [ [ "species_114519", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10740115": { "compartment": "compartment_70101", "id": "reaction_10740115", "reactome": "R-SPO-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740085" ], "products": [ "species_10740113" ], "modifiers": [], "additional_components": [ "O94590", "SPCC584.05", "P28758", "SPAC821.10c", "P04689", "SPBC800.05c", "P05933", "SPAC3A12.14", "O60054", "SPBC56F2.03", "O14008", "SPAC29A4.05", "P04688", "SPBC16A3.15c", "P10989", "SPBC32H8.12c", "O42914", "SPBC16A3.08c", "O14301", "SPAC9G1.05", "O94590", "SPCC584.05", "P28758", "SPAC821.10c", "P04689", "SPBC800.05c", "P05933", "SPAC3A12.14", "O60054", "SPBC56F2.03", "O14008", "SPAC29A4.05", "P04688", "SPBC16A3.15c", "P10989", "SPBC32H8.12c", "O42914", "SPBC16A3.08c", "O14301", "SPAC9G1.05" ] }, "reaction_10740026": { "compartment": "compartment_876", "id": "reaction_10740026", "reactome": "R-SPO-481009", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740020" ], "products": [ "species_10740024" ], "modifiers": [], "additional_components": [ "O94740", "SPBC9B6.10", "species_29372", "species_74016", "species_113592", "species_29370", "species_111294", "CHEBI:15996", "species_111349", "species_29926", "species_209914", "species_29420", "O94740", "SPBC9B6.10", "species_29372", "species_74016", "species_113592", "species_29370", "species_29438", "species_111294", "species_29926", "species_209914" ] }, "reaction_10739124": { "compartment": "compartment_114584", "id": "reaction_10739124", "reactome": "R-SPO-429157", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29372", "species_114565" ], "modifiers": [ [ "species_10739121", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10740013": { "compartment": "compartment_876", "id": "reaction_10740013", "reactome": "R-SPO-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739997" ], "products": [ "species_10740011" ], "modifiers": [], "additional_components": [ "P78768", "SPBC3B9.10", "O13998", "SPAC27E2.03c", "O13728", "SPAC15A10.08", "Q9Y7U4", "SPCC645.04", "P78768", "SPBC3B9.10", "O13998", "SPAC27E2.03c", "O13728", "SPAC15A10.08", "Q9Y7U4", "SPCC645.04" ] }, "reaction_10736228": { "compartment": "compartment_984", "id": "reaction_10736228", "reactome": "R-SPO-192430", "name": "Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171126", "species_109276" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10736220", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "Q8TFG4", "SPAPB18E9.04c", "CHEBI:16755", "CHEBI:16359", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274" ] }, "reaction_10755696": { "compartment": "compartment_984", "id": "reaction_10755696", "reactome": "R-SPO-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878780", "species_109276" ], "products": [ "species_109277", "species_8878776" ], "modifiers": [ [ "species_10755693", "catalyst" ] ], "additional_components": [ "species_442320", "O60109", "SPBC14F5.13c", "species_74016" ] }, "reaction_10736223": { "compartment": "compartment_984", "id": "reaction_10736223", "reactome": "R-SPO-192417", "name": "Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171076" ], "products": [ "species_174602", "species_171149" ], "modifiers": [ [ "species_10736220", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "Q8TFG4", "SPAPB18E9.04c", "CHEBI:16755", "CHEBI:16359", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274" ] }, "reaction_10736226": { "compartment": "compartment_984", "id": "reaction_10736226", "reactome": "R-SPO-192425", "name": "Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_6814795" ], "products": [ "species_192438", "species_174602" ], "modifiers": [ [ "species_10736220", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "Q8TFG4", "SPAPB18E9.04c", "CHEBI:16755", "CHEBI:16359", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274" ] }, "reaction_10757949": { "compartment": "compartment_70101", "id": "reaction_10757949", "reactome": "R-SPO-9696275", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757914" ], "products": [ "species_10757916" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10740224": { "compartment": "compartment_70101", "id": "reaction_10740224", "reactome": "R-SPO-548831", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_548809" ], "products": [ "species_29366", "species_428139" ], "modifiers": [ [ "species_10740221", "catalyst" ] ], "additional_components": [ "O94511", "SPBC646.07c" ] }, "reaction_10740231": { "compartment": "compartment_70101", "id": "reaction_10740231", "reactome": "R-SPO-548843", "name": "ACSL3,4 ligate CoA to AA to form AA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_29768", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_548819" ], "modifiers": [ [ "species_10740228", "catalyst" ] ], "additional_components": [ "Q9P7D7", "SPBP4H10.11c", "O60135", "SPBC18H10.02" ] }, "reaction_10747097": { "compartment": "compartment_12045", "id": "reaction_10747097", "reactome": "R-SPO-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_5676634", "species_29356" ], "modifiers": [ [ "species_10747094", "catalyst" ] ], "additional_components": [ "O14346", "SPBC19C2.15c" ] }, "reaction_10736922": { "compartment": "compartment_70101", "id": "reaction_10736922", "reactome": "R-SPO-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_200993" ], "modifiers": [ [ "species_10736919", "catalyst" ] ], "additional_components": [ "Q9P7D7", "SPBP4H10.11c", "O60135", "SPBC18H10.02" ] }, "reaction_10738479": { "compartment": "compartment_876", "id": "reaction_10738479", "reactome": "R-SPO-399998", "name": "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10738476", "catalyst" ] ], "additional_components": [ "P40977", "SPAC22F8.11", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10734981": { "compartment": "compartment_7660", "id": "reaction_10734981", "reactome": "R-SPO-163664", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164121", "species_10734975" ], "products": [ "species_10734979" ], "modifiers": [], "additional_components": [ "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10733346": { "compartment": "compartment_7660", "id": "reaction_10733346", "reactome": "R-SPO-75864", "name": "Newly Formed Phosphodiester Bond Stabilized and PPi Released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733344" ], "products": [ "species_10732713", "species_113541" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10733338": { "compartment": "compartment_7660", "id": "reaction_10733338", "reactome": "R-SPO-75861", "name": "NTP Binds Active Site of RNA Polymerase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733332" ], "products": [ "species_10733336" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10733348": { "compartment": "compartment_7660", "id": "reaction_10733348", "reactome": "R-SPO-75866", "name": "Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733336" ], "products": [ "species_10733344" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10743710": { "compartment": "compartment_7660", "id": "reaction_10743710", "reactome": "R-SPO-2997723", "name": "PIAS4 SUMOylates TP53BP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743694", "species_10743647" ], "products": [ "species_10743639", "species_10743702" ], "modifiers": [ [ "species_10743707", "catalyst" ] ], "additional_components": [ "SPBC342.05", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P87074", "SPBC342.05", "SPAC1687.05" ] }, "reaction_10744668": { "compartment": "compartment_7660", "id": "reaction_10744668", "reactome": "R-SPO-3968414", "name": "UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744646" ], "products": [ "species_10743639", "species_10744663" ], "modifiers": [ [ "species_10744665", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O43058", "SPBC4C3.12", "O13606", "SPBC32H8.11", "SPAC30D11.13", "O43058", "SPBC4C3.12", "O13606", "SPBC32H8.11", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O94451", "SPAC1687.05" ] }, "reaction_10751307": { "compartment": "compartment_7660", "id": "reaction_10751307", "reactome": "R-SPO-6798372", "name": "ATM phosphorylates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10751295" ], "products": [ "species_113582", "species_10751305" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "SPCC23B6.03c" ] }, "reaction_10751322": { "compartment": "compartment_7660", "id": "reaction_10751322", "reactome": "R-SPO-6798373", "name": "MDM2 ubiquitinates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751295", "species_10729044" ], "products": [ "species_10751315" ], "modifiers": [ [ "species_10751319", "catalyst" ] ], "additional_components": [ "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "O74503", "SPCC285.17" ] }, "reaction_10752579": { "compartment": "compartment_7660", "id": "reaction_10752579", "reactome": "R-SPO-6805061", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734359", "species_10752575" ], "products": [ "species_10752577" ], "modifiers": [], "additional_components": [ "O94529", "SPBC609.05", "O94267", "SPBP8B7.19", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11", "O94529", "SPBC609.05", "O94267", "SPBP8B7.19" ] }, "reaction_10745446": { "compartment": "compartment_13231", "id": "reaction_10745446", "reactome": "R-SPO-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10744759", "catalyst" ] ], "additional_components": [ "SPAC1952.13" ] }, "reaction_10744778": { "compartment": "compartment_13231", "id": "reaction_10744778", "reactome": "R-SPO-4419948", "name": "CTDNEP1:CNEP1R1 dephosphorylates LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10744753" ], "products": [ "species_10744759", "species_113550" ], "modifiers": [ [ "species_10744775", "catalyst" ] ], "additional_components": [ "SPAC1952.13", "SPAC1952.13", "Q9USQ0", "SPBC902.03", "O59718", "SPBC3B8.10c" ] }, "reaction_10742056": { "compartment": "compartment_12045", "id": "reaction_10742056", "reactome": "R-SPO-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_109395", "species_1500581" ], "modifiers": [ [ "species_10742053", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "O13901", "SPAC22A12.10" ] }, "reaction_10742027": { "compartment": "compartment_12045", "id": "reaction_10742027", "reactome": "R-SPO-1482900", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498740", "species_1524021" ], "modifiers": [ [ "species_10741849", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742073": { "compartment": "compartment_12045", "id": "reaction_10742073", "reactome": "R-SPO-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_109395", "species_426639" ], "modifiers": [ [ "species_10742070", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "Q10153", "SPAC1D4.08" ] }, "reaction_10742110": { "compartment": "compartment_12045", "id": "reaction_10742110", "reactome": "R-SPO-1483081", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_1524071" ], "products": [ "species_111294", "species_1524060" ], "modifiers": [ [ "species_10742107", "catalyst" ] ], "additional_components": [ "O74975", "SPCC1827.02c" ] }, "reaction_10742173": { "compartment": "compartment_70101", "id": "reaction_10742173", "reactome": "R-SPO-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10742170", "catalyst" ] ], "additional_components": [ "Q10276", "SPAC13G7.12c" ] }, "reaction_10749967": { "compartment": "compartment_12045", "id": "reaction_10749967", "reactome": "R-SPO-5696448", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696449", "species_6782195" ], "products": [ "species_76194", "species_1500596" ], "modifiers": [ [ "species_10749964", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10742021": { "compartment": "compartment_12045", "id": "reaction_10742021", "reactome": "R-SPO-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10740247", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10741961": { "compartment": "compartment_70616", "id": "reaction_10741961", "reactome": "R-SPO-1482745", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524027" ], "modifiers": [ [ "species_10741958", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742032": { "compartment": "compartment_12045", "id": "reaction_10742032", "reactome": "R-SPO-1482920", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498730", "species_1524021" ], "modifiers": [ [ "species_10742029", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10753720": { "compartment": "compartment_12045", "id": "reaction_10753720", "reactome": "R-SPO-8848580", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10753715", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10741907": { "compartment": "compartment_12045", "id": "reaction_10741907", "reactome": "R-SPO-1482685", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10749937": { "compartment": "compartment_17906", "id": "reaction_10749937", "reactome": "R-SPO-5696074", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696069", "species_5696066" ], "products": [ "species_5696026", "species_5696037" ], "modifiers": [ [ "species_10749934", "catalyst" ] ], "additional_components": [ "species_1500596", "species_6814795", "species_1500590", "species_417891", "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04", "species_29926" ] }, "reaction_10741782": { "compartment": "compartment_12045", "id": "reaction_10741782", "reactome": "R-SPO-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_29356" ], "products": [ "species_76116", "species_1500593" ], "modifiers": [ [ "species_10741779", "catalyst" ] ], "additional_components": [ "O94305", "SPCC5E4.05c" ] }, "reaction_10742017": { "compartment": "compartment_12045", "id": "reaction_10742017", "reactome": "R-SPO-1482868", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742037": { "compartment": "compartment_12045", "id": "reaction_10742037", "reactome": "R-SPO-1482932", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498737", "species_1524021" ], "modifiers": [ [ "species_10742034", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741888": { "compartment": "compartment_12045", "id": "reaction_10741888", "reactome": "R-SPO-1482626", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498737", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10741814", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10742002": { "compartment": "compartment_70616", "id": "reaction_10742002", "reactome": "R-SPO-1482847", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524047" ], "modifiers": [ [ "species_10741958", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741852": { "compartment": "compartment_17906", "id": "reaction_10741852", "reactome": "R-SPO-1482604", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590", "species_29356" ], "products": [ "species_1524103", "species_1500580" ], "modifiers": [ [ "species_10741849", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742010": { "compartment": "compartment_12045", "id": "reaction_10742010", "reactome": "R-SPO-1482861", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524069", "species_1500578" ], "products": [ "species_76194", "species_1524081" ], "modifiers": [ [ "species_10733368", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10742120": { "compartment": "compartment_12045", "id": "reaction_10742120", "reactome": "R-SPO-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_426955", "species_111294" ], "modifiers": [ [ "species_10742117", "catalyst" ] ], "additional_components": [ "Q9P381", "SPBC13A2.03", "species_29926" ] }, "reaction_10741807": { "compartment": "compartment_70616", "id": "reaction_10741807", "reactome": "R-SPO-1482546", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524047", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10741804", "catalyst" ] ], "additional_components": [ "SPAC22A12.08c" ] }, "reaction_10741890": { "compartment": "compartment_12045", "id": "reaction_10741890", "reactome": "R-SPO-1482629", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10755107": { "compartment": "compartment_70101", "id": "reaction_10755107", "reactome": "R-SPO-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_426639" ], "products": [ "species_426658", "species_426755" ], "modifiers": [ [ "species_10755104", "catalyst" ] ], "additional_components": [ "Q7LKZ6", "SPCC1020.13c", "P87109", "SPAC20G8.02" ] }, "reaction_10742133": { "compartment": "compartment_12045", "id": "reaction_10742133", "reactome": "R-SPO-1483174", "name": "PE is methylated to PC by PEMT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_71284" ], "products": [ "species_426925", "species_71285" ], "modifiers": [ [ "species_10742130", "catalyst" ] ], "additional_components": [ "SPBC337.16" ] }, "reaction_10741817": { "compartment": "compartment_12045", "id": "reaction_10741817", "reactome": "R-SPO-1482598", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498733", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10741814", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741910": { "compartment": "compartment_70616", "id": "reaction_10741910", "reactome": "R-SPO-1482689", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524027", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10741804", "catalyst" ] ], "additional_components": [ "SPAC22A12.08c" ] }, "reaction_10742063": { "compartment": "compartment_20699", "id": "reaction_10742063", "reactome": "R-SPO-1482973", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524057", "species_1524060" ], "products": [ "species_109395", "species_429785" ], "modifiers": [ [ "species_10742060", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "O13901", "SPAC22A12.10" ] }, "reaction_10742015": { "compartment": "compartment_12045", "id": "reaction_10742015", "reactome": "R-SPO-1482867", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524080", "species_1500578" ], "products": [ "species_76194", "species_1524069" ], "modifiers": [ [ "species_10733368", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10741893": { "compartment": "compartment_12045", "id": "reaction_10741893", "reactome": "R-SPO-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10741772", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10741885": { "compartment": "compartment_12045", "id": "reaction_10741885", "reactome": "R-SPO-1482612", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742091": { "compartment": "compartment_70101", "id": "reaction_10742091", "reactome": "R-SPO-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_264618" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10742088", "catalyst" ] ], "additional_components": [ "Q10276", "SPAC13G7.12c" ] }, "reaction_10742153": { "compartment": "compartment_12045", "id": "reaction_10742153", "reactome": "R-SPO-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_428686" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10742150", "catalyst" ] ], "additional_components": [ "Q9UTI6", "SPAC15E1.05c" ] }, "reaction_10742094": { "compartment": "compartment_70616", "id": "reaction_10742094", "reactome": "R-SPO-1483063", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_1524064" ], "products": [ "species_1524067", "species_1524072" ], "modifiers": [ [ "species_10741804", "catalyst" ] ], "additional_components": [ "SPAC22A12.08c" ] }, "reaction_10741980": { "compartment": "compartment_70616", "id": "reaction_10741980", "reactome": "R-SPO-1482759", "name": "MLCL is hydrolyzed to DLCL by PLA2G4A (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498773", "species_113521" ], "products": [ "species_1524085", "species_1498753" ], "modifiers": [ [ "species_10741977", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741902": { "compartment": "compartment_70101", "id": "reaction_10741902", "reactome": "R-SPO-1482656", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10741849", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10733396": { "compartment": "compartment_70101", "id": "reaction_10733396", "reactome": "R-SPO-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_75970" ], "products": [ "species_29360", "species_76114" ], "modifiers": [ [ "species_10733393", "catalyst" ] ], "additional_components": [ "Q09845", "SPAC23D3.04c", "P21696", "SPBC215.05" ] }, "reaction_10749957": { "compartment": "compartment_5460", "id": "reaction_10749957", "reactome": "R-SPO-5696415", "name": "PXLP-K278-ETNPPL tetramer hydrolyses PETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_5696414" ], "products": [ "species_113548", "species_5693978", "species_113532" ], "modifiers": [ [ "species_10749954", "catalyst" ] ], "additional_components": [ "Q9US34", "SPAC1039.07c" ] }, "reaction_10741914": { "compartment": "compartment_12045", "id": "reaction_10741914", "reactome": "R-SPO-1482696", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10750442": { "compartment": "compartment_70101", "id": "reaction_10750442", "reactome": "R-SPO-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10750439", "catalyst" ] ], "additional_components": [ "Q7LKZ6", "SPCC1020.13c", "P87109", "SPAC20G8.02" ] }, "reaction_10741991": { "compartment": "compartment_12045", "id": "reaction_10741991", "reactome": "R-SPO-1482825", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10741988", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742143": { "compartment": "compartment_12045", "id": "reaction_10742143", "reactome": "R-SPO-1483182", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_264618", "species_426755" ], "modifiers": [ [ "species_10742138", "catalyst" ] ], "additional_components": [ "SPAC2F7.16c" ] }, "reaction_10741775": { "compartment": "compartment_12045", "id": "reaction_10741775", "reactome": "R-SPO-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498740", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10741772", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10733373": { "compartment": "compartment_12045", "id": "reaction_10733373", "reactome": "R-SPO-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_76194", "species_426755" ], "modifiers": [ [ "species_10733370", "catalyst" ] ], "additional_components": [ "O94361", "SPBC428.14", "Q9US20", "SPAC1851.02" ] }, "reaction_10755689": { "compartment": "compartment_5460", "id": "reaction_10755689", "reactome": "R-SPO-8878654", "name": "ACP6 hydrolyses MYS-LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878649", "species_113521" ], "products": [ "species_8934414", "species_113548" ], "modifiers": [ [ "species_10755686", "catalyst" ] ], "additional_components": [ "SPBC4.06" ] }, "reaction_10742164": { "compartment": "compartment_12045", "id": "reaction_10742164", "reactome": "R-SPO-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10742161", "catalyst" ] ], "additional_components": [ "Q9UUJ6", "SPAC1952.13", "species_29926" ] }, "reaction_10742047": { "compartment": "compartment_12045", "id": "reaction_10742047", "reactome": "R-SPO-1482961", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524060", "species_1500596" ], "products": [ "species_109395", "species_426925" ], "modifiers": [ [ "species_10742044", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "O13901", "SPAC22A12.10" ] }, "reaction_10756967": { "compartment": "compartment_70101", "id": "reaction_10756967", "reactome": "R-SPO-9018824", "name": "RHOT2 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756963", "species_10756946" ], "products": [ "species_10756965" ], "modifiers": [], "additional_components": [ "O74805", "SPBC2D10.14c", "Q9USY7", "SPBC1706.03", "O94477", "SPCC1919.10c", "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "O74805", "SPBC2D10.14c", "Q9USY7", "SPBC1706.03", "species_29438", "O94477", "SPCC1919.10c" ] }, "reaction_10756969": { "compartment": "compartment_70101", "id": "reaction_10756969", "reactome": "R-SPO-9018826", "name": "RHOT2 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756946", "species_29356" ], "products": [ "species_10756948", "species_29372" ], "modifiers": [ [ "species_10756946", "catalyst" ] ], "additional_components": [ "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "species_29420", "O59781", "SPCC320.04c", "species_29438" ] }, "reaction_10757850": { "compartment": "compartment_876", "id": "reaction_10757850", "reactome": "R-SPO-9693111", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757845" ], "products": [ "species_10757847", "species_29420" ], "modifiers": [ [ "species_10757845", "catalyst" ] ], "additional_components": [ "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01" ] }, "reaction_10757896": { "compartment": "compartment_876", "id": "reaction_10757896", "reactome": "R-SPO-9693282", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757847", "species_29356" ], "products": [ "species_29372", "species_10757845" ], "modifiers": [ [ "species_10756838", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10752557": { "compartment": "compartment_7660", "id": "reaction_10752557", "reactome": "R-SPO-6804955", "name": "ATM phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737757" ], "products": [ "species_113582", "species_10752555" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "SPCC23B6.03c" ] }, "reaction_10755684": { "compartment": "compartment_7660", "id": "reaction_10755684", "reactome": "R-SPO-8877692", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740775", "species_10755677" ], "products": [ "species_10755682" ], "modifiers": [], "additional_components": [ "SPCC16C4.03", "O13853", "SPAC19G12.14", "O74448", "SPCC16C4.03", "O13853", "SPAC19G12.14" ] }, "reaction_10737784": { "compartment": "compartment_7660", "id": "reaction_10737784", "reactome": "R-SPO-349455", "name": "Phosphorylation of MDM4 by ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737774" ], "products": [ "species_113582", "species_10737762" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "O74503", "SPCC285.17", "SPCC23B6.03c" ] }, "reaction_10751191": { "compartment": "compartment_70101", "id": "reaction_10751191", "reactome": "R-SPO-6793666", "name": "MDM2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736549" ], "products": [ "species_10737757" ], "modifiers": [], "additional_components": [ "SPCC285.17", "SPCC285.17" ] }, "reaction_10752603": { "compartment": "compartment_7660", "id": "reaction_10752603", "reactome": "R-SPO-6805640", "name": "AKT phosphorylates KAT6A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10752596" ], "products": [ "species_113582", "species_10752601" ], "modifiers": [ [ "species_10736722", "catalyst" ] ], "additional_components": [ "O14240", "SPAC6F6.09", "O74736", "SPBC1709.11c", "O94446", "SPAC637.12c", "O42871", "SPAC3G9.08", "O14240", "SPAC6F6.09", "O74736", "SPBC1709.11c", "O94446", "SPAC637.12c", "O42871", "SPAC3G9.08", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10752539": { "compartment": "compartment_7660", "id": "reaction_10752539", "reactome": "R-SPO-6804724", "name": "MDM2 ubiquitinates phosphorylated MDM4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737768", "species_10729044" ], "products": [ "species_10752536" ], "modifiers": [ [ "species_10737768", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74503", "SPCC285.17", "O74503", "SPCC285.17" ] }, "reaction_10751207": { "compartment": "compartment_70101", "id": "reaction_10751207", "reactome": "R-SPO-6795290", "name": "TORC2 complex phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10751197" ], "products": [ "species_29370", "species_10751205" ], "modifiers": [ [ "species_10736612", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "O14208", "SPAC6B12.03c", "Q09743", "SPBC12C2.02c", "Q9Y7K2", "SPBC216.07c", "O74547", "SPCC777.08c", "O74184", "SPBC21B10.05c", "Q9P7Y9", "SPAPYUG7.02c" ] }, "reaction_10751220": { "compartment": "compartment_70101", "id": "reaction_10751220", "reactome": "R-SPO-6795473", "name": "PDPK1 phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10751205" ], "products": [ "species_29370", "species_10751215" ], "modifiers": [ [ "species_10733718", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10752549": { "compartment": "compartment_7660", "id": "reaction_10752549", "reactome": "R-SPO-6804942", "name": "MDM2 homodimers auto-ubiquitinate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751317", "species_10729044" ], "products": [ "species_10752546" ], "modifiers": [ [ "species_10751317", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74503", "SPCC285.17", "O74503", "SPCC285.17" ] }, "reaction_10751189": { "compartment": "compartment_7660", "id": "reaction_10751189", "reactome": "R-SPO-6793661", "name": "(CDK1,CDK2):CCNA phosphorylates MDM2 at T218", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737757" ], "products": [ "species_113582", "species_10751172" ], "modifiers": [ [ "species_10728937", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10753231": { "compartment": "compartment_7660", "id": "reaction_10753231", "reactome": "R-SPO-6810376", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744714", "species_6810408" ], "products": [ "species_10753229" ], "modifiers": [], "additional_components": [ "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08", "species_422529", "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08" ] }, "reaction_10737770": { "compartment": "compartment_7660", "id": "reaction_10737770", "reactome": "R-SPO-349426", "name": "Phosphorylation of MDM4 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737762" ], "products": [ "species_113582", "species_10737768" ], "modifiers": [ [ "species_10729617", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "O74503", "SPCC285.17", "SPAC14C4.03" ] }, "reaction_10751222": { "compartment": "compartment_70101", "id": "reaction_10751222", "reactome": "R-SPO-6795667", "name": "MDM2 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743716" ], "products": [ "species_10736545" ], "modifiers": [], "additional_components": [ "SPCC285.17", "SPCC285.17" ] }, "reaction_10752543": { "compartment": "compartment_7660", "id": "reaction_10752543", "reactome": "R-SPO-6804741", "name": "MDM2 forms homo- or heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752541", "species_10737757" ], "products": [ "species_10751319" ], "modifiers": [ [ "species_10737781", "inhibitor" ] ], "additional_components": [ "O74503", "SPCC285.17", "SPCC285.17", "O74503", "SPCC285.17", "SPCC23B6.03c" ] }, "reaction_10755680": { "compartment": "compartment_7660", "id": "reaction_10755680", "reactome": "R-SPO-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10755666" ], "products": [ "species_113582", "species_10755677" ], "modifiers": [ [ "species_10739756", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14", "O13853", "SPAC19G12.14", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c" ] }, "reaction_10751218": { "compartment": "compartment_70101", "id": "reaction_10751218", "reactome": "R-SPO-6795460", "name": "SGK1 phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736545", "species_113592" ], "products": [ "species_29370", "species_10736549" ], "modifiers": [ [ "species_10751215", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10751262": { "compartment": "compartment_7660", "id": "reaction_10751262", "reactome": "R-SPO-6797616", "name": "CCNK:CDK12 binds RNA Pol II at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751226", "species_10751242" ], "products": [ "species_10751244" ], "modifiers": [], "additional_components": [ "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c" ] }, "reaction_10751260": { "compartment": "compartment_7660", "id": "reaction_10751260", "reactome": "R-SPO-6797606", "name": "CDK12 phosphorylates RNA Pol II CTD at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10751244" ], "products": [ "species_113582", "species_10751257" ], "modifiers": [ [ "species_10751244", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c" ] }, "reaction_10751234": { "compartment": "compartment_7660", "id": "reaction_10751234", "reactome": "R-SPO-6797100", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734263", "species_10751230" ], "products": [ "species_10751232" ], "modifiers": [], "additional_components": [ "SPBC32F12.06", "SPAC2F3.15", "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15" ] }, "reaction_10751228": { "compartment": "compartment_7660", "id": "reaction_10751228", "reactome": "R-SPO-6797090", "name": "CCNK binds CDK12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734263", "species_10751224" ], "products": [ "species_10751226" ], "modifiers": [], "additional_components": [ "SPBC32F12.06", "SPAC2F3.15", "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15" ] }, "reaction_10739697": { "compartment": "compartment_5460", "id": "reaction_10739697", "reactome": "R-SPO-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113539", "species_113593" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10739694", "catalyst" ] ], "additional_components": [ "SPCC191.02c" ] }, "reaction_10730535": { "compartment": "compartment_70101", "id": "reaction_10730535", "reactome": "R-SPO-71707", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30203", "species_29360" ], "products": [ "species_70106", "species_73473", "species_29510" ], "modifiers": [ [ "species_10730532", "catalyst" ] ], "additional_components": [ "species_442320", "P78870", "SPCC13B11.04c", "O74540", "SPCC13B11.04c" ] }, "reaction_10730567": { "compartment": "compartment_70101", "id": "reaction_10730567", "reactome": "R-SPO-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_113592", "species_29416" ], "products": [ "species_111294", "species_76577", "species_76183" ], "modifiers": [ [ "species_10730564", "catalyst" ] ], "additional_components": [ "SPCC191.02c" ] }, "reaction_10745912": { "compartment": "compartment_876", "id": "reaction_10745912", "reactome": "R-SPO-5433067", "name": "DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490235" ], "products": [ "species_266029", "species_5490250" ], "modifiers": [ [ "species_10737679", "catalyst" ] ], "additional_components": [ "CHEBI:78579", "CHEBI:78584", "CHEBI:78578", "CHEBI:78583", "O59832", "SPCC965.12", "species_442320", "O14124", "SPCC965.12" ] }, "reaction_10730490": { "compartment": "compartment_70101", "id": "reaction_10730490", "reactome": "R-SPO-71691", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29510", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_29416" ], "modifiers": [ [ "species_10730487", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10730542": { "compartment": "compartment_5460", "id": "reaction_10730542", "reactome": "R-SPO-71723", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730539", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10749939": { "compartment": "compartment_5460", "id": "reaction_10749939", "reactome": "R-SPO-5696091", "name": "ALDH1B1 tetramer oxidises CH3CHO to CH3COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730539", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10745935": { "compartment": "compartment_984", "id": "reaction_10745935", "reactome": "R-SPO-5433072", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490253", "species_109276" ], "products": [ "species_210382", "species_5490235" ], "modifiers": [ [ "species_10745932", "catalyst" ] ], "additional_components": [ "CHEBI:78587", "CHEBI:78581", "CHEBI:78579", "CHEBI:78584", "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10749510": { "compartment": "compartment_70101", "id": "reaction_10749510", "reactome": "R-SPO-5692237", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692221", "species_29360" ], "products": [ "species_73473", "species_70106", "species_5692249" ], "modifiers": [ [ "species_10749507", "catalyst" ] ], "additional_components": [ "species_442320", "O74540", "SPCC13B11.04c" ] }, "reaction_10747760": { "compartment": "compartment_12045", "id": "reaction_10747760", "reactome": "R-SPO-5689000", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5689006", "species_29356" ], "products": [ "species_5688995", "species_5689001" ], "modifiers": [ [ "species_10747757", "catalyst" ] ], "additional_components": [ "Q9US38", "SPAPB1A11.02", "Q9HDX3", "SPAPB1A11.02" ] }, "reaction_10734961": { "compartment": "compartment_5460", "id": "reaction_10734961", "reactome": "R-SPO-163310", "name": "TFAM binds to mitochondrial promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163305", "species_10734957" ], "products": [ "species_10734959" ], "modifiers": [], "additional_components": [ "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c", "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c" ] }, "reaction_10743032": { "compartment": "compartment_7660", "id": "reaction_10743032", "reactome": "R-SPO-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10743025", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10743029" ], "modifiers": [ [ "species_10743025", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "species_113531", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "O94603", "SPCC622.16c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "species_113531", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "O94603", "SPCC622.16c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "species_113531", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "O94603", "SPCC622.16c" ] }, "reaction_10758000": { "compartment": "compartment_12045", "id": "reaction_10758000", "reactome": "R-SPO-9714361", "name": "RHOC activates endoplasmic reticulum effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757996", "species_10757971" ], "products": [ "species_10757998" ], "modifiers": [], "additional_components": [ "O13644", "SPBC8D2.14c", "O42707", "SPCC126.08c", "Q09195", "SPBC16G5.18", "Q10484", "SPAC17C9.12", "O94401", "SPCC126.08c", "O60119", "SPBC16G5.05c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "O13644", "SPBC8D2.14c", "Q9HE04", "SPAC20H4.11c", "O42707", "SPCC126.08c", "Q09195", "SPBC16G5.18", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q10484", "SPAC17C9.12", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O94401", "SPCC126.08c", "species_29438", "O60119", "SPBC16G5.05c" ] }, "reaction_10758002": { "compartment": "compartment_876", "id": "reaction_10758002", "reactome": "R-SPO-9714363", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746673" ], "products": [ "species_10757971" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10756748": { "compartment": "compartment_876", "id": "reaction_10756748", "reactome": "R-SPO-9013111", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746673", "species_29356" ], "products": [ "species_10756724", "species_29372" ], "modifiers": [ [ "species_10756508", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10756740": { "compartment": "compartment_70101", "id": "reaction_10756740", "reactome": "R-SPO-9013108", "name": "GDIs block activation of RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756724", "species_10756674" ], "products": [ "species_10756738" ], "modifiers": [], "additional_components": [ "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "SPAC6F12.06", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O14224", "SPAC6F12.06" ] }, "reaction_10756746": { "compartment": "compartment_876", "id": "reaction_10756746", "reactome": "R-SPO-9013110", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746673", "species_10756742" ], "products": [ "species_10756744" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q10201", "SPBC17D1.07c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "P78953", "SPCC4B3.15", "Q92356", "SPAC6G9.11", "O14188", "SPAC4F8.13c", "O43027", "SPBC354.13", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "O43027", "SPBC354.13", "Q10133", "SPAC16.01", "species_29438", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c" ] }, "reaction_10736357": { "compartment": "compartment_70101", "id": "reaction_10736357", "reactome": "R-SPO-196060", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_196095" ], "products": [ "species_29366", "species_196066" ], "modifiers": [ [ "species_10736354", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10744363": { "compartment": "compartment_7660", "id": "reaction_10744363", "reactome": "R-SPO-3662318", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732874", "species_113560" ], "products": [ "species_2485002", "species_10744336" ], "modifiers": [ [ "species_10744360", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "Q9UTM7", "SPAC139.06", "O94244", "SPCC1672.10" ] }, "reaction_10744059": { "compartment": "compartment_7660", "id": "reaction_10744059", "reactome": "R-SPO-3318415", "name": "ATF2 acetylates histone H2B, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744046", "species_113560" ], "products": [ "species_2485002", "species_10744056" ], "modifiers": [ [ "species_10735245", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04913", "SPCC622.09", "P09322", "SPAC1834.03c", "P04913", "SPCC622.09", "P52890", "SPBC29B5.01", "P78962", "SPBC2F12.09c", "Q09771", "SPAC22F3.02" ] }, "reaction_10756972": { "compartment": "compartment_70101", "id": "reaction_10756972", "reactome": "R-SPO-9018862", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9022655" ], "products": [ "species_9022660" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10742548": { "compartment": "compartment_70101", "id": "reaction_10742548", "reactome": "R-SPO-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742542", "species_10742544" ], "products": [ "species_10742546" ], "modifiers": [], "additional_components": [ "P21565", "SPCC188.06c", "O74436", "SPCC1682.05c", "O59787", "SPCC320.10", "O13804", "SPAC17H9.07", "O94407", "SPCC126.15c", "Q9P372", "SPAC19B12.09", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", 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"Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740756" ], "products": [ "species_10733183", "species_10740705", "species_10734667", "species_10740725", "species_10740717", "species_10731799", "species_10740723", "species_10740674" ], "modifiers": [ [ "species_10740705", "catalyst" ], [ "species_10740752", "catalyst" ] ], "additional_components": [ "Q9P6M8", "SPAC1610.03c", "Q10475", "SPAC17C9.03", "P31209", "SPAC57A7.04c", "Q09820", "SPAC16C9.06c", "O14338", "SPBC2F12.03c", "Q9UT08", "SPAP8A3.09c", "Q9P383", "SPBC13A2.01c", "P23636", "SPBC16H5.07c", "O14253", "SPAC6G10.07", "O74804", "SPBC2D10.13", "Q12702", "SPAC57A7.04c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "Q9P6M8", "SPAC1610.03c", "P31209", "SPAC57A7.04c", "SPBC2D10.13", "O14338", "SPBC2F12.03c", "O74804", "SPBC2D10.13", "SPAC17C9.03", "O14338", "SPBC2F12.03c", "O74804", "SPBC2D10.13", "SPAC16C9.06c", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "SPAC16C9.06c" ] }, "reaction_10740770": { "compartment": "compartment_70101", "id": "reaction_10740770", "reactome": "R-SPO-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740767", "species_113592" ], "products": [ "species_29370", "species_10740754" ], "modifiers": [ [ "species_10740767", "catalyst" ] ], "additional_components": [ "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", 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"SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "O43037", "SPBC3B9.08c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "Q10267", "SPAC13G7.03", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "Q1MTR2", "SPBC13G1.14c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07" ] }, "reaction_10740765": { "compartment": "compartment_70101", "id": "reaction_10740765", "reactome": "R-SPO-927836", "name": "SMG6 hydrolyzes mRNA with premature termination codon", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740762" ], "products": [ "species_10740756" ], "modifiers": [ [ "species_10740762", "catalyst" ] ], "additional_components": [ "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "Q12702", "SPAC57A7.04c", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "Q9UT08", "SPAP8A3.09c", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", 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"Q09757", "SPAC24H6.07", "Q10055", "SPAC1F5.10", "P05764", "SPBC18E5.06", "O42699", "SPCC1682.14", "O13824", "SPAC19A8.08", "P0CT83", "SPCC16C4.13c", "Q9P4W9", "SPAC959.07", "P23636", "SPBC16H5.07c", "Q9US22", "SPAC1783.08c", "O74172", "SPBC3D6.15", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "Q9P546", "SPAPJ698.02c", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "O43037", "SPBC3B9.08c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "Q10267", "SPAC13G7.03", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "O74804", "SPBC2D10.13", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "O14338", "SPBC2F12.03c", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "Q1MTR2", "SPBC13G1.14c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07" ] }, "reaction_10755910": { "compartment": "compartment_876", "id": "reaction_10755910", "reactome": "R-SPO-8941234", "name": "SH3PXD2A binds ADAM12,ADAM15,ADAM19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755902", "species_10755900" ], "products": [ "species_10755908" ], "modifiers": [], "additional_components": [ "SPAC17A5.04c", "species_202247", "P40996", "SPAC22H10.07", "species_202247", "P40996", "SPAC22H10.07", "O13766", "SPAC17A5.04c" ] }, "reaction_10740377": { "compartment": "compartment_70101", "id": "reaction_10740377", "reactome": "R-SPO-893596", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29970" ], "products": [ "species_893615", "species_29432" ], "modifiers": [ [ "species_10740371", "catalyst" ], [ "species_8939576", "inhibitor" ], [ "species_29502", "inhibitor" ] ], "additional_components": [ "O14209", "SPAC6B12.04c", "CHEBI:55528", "CHEBI:43580" ] }, "reaction_10749439": { "compartment": "compartment_70101", "id": "reaction_10749439", "reactome": "R-SPO-5690319", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10749434" ], "products": [ "species_1131871", "species_10749436" ], "modifiers": [ [ "species_10749434", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10171", "SPAC27F1.03c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10171", "SPAC27F1.03c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10171", "SPAC27F1.03c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10744634": { "compartment": "compartment_7660", "id": "reaction_10744634", "reactome": "R-SPO-3968362", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10743707" ], "products": [ "species_10743639", "species_10744632" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC1687.05", "SPAC30D11.13", "O13351", "SPBC365.06", "O94451", "SPAC1687.05", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750477": { "compartment": "compartment_12045", "id": "reaction_10750477", "reactome": "R-SPO-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_6788758", "species_71285" ], "modifiers": [ [ "species_10750474", "catalyst" ] ], "additional_components": [ "species_442320", "P87014", "SPAC10F6.12c" ] }, "reaction_10734835": { "compartment": "compartment_70101", "id": "reaction_10734835", "reactome": "R-SPO-162730", "name": "phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_162756" ], "products": [ "species_110096", "species_8855657" ], "modifiers": [ [ "species_10734832", "catalyst" ] ], "additional_components": [ "O59802", "SPCC550.04c", "Q9USW6", "SPBC21B10.11", "P87172", "SPBC3D6.07", "Q9Y7L7", "SPBC685.05", "O13904", "SPAC22A12.13", "O14357", "SPBC30D10.11" ] }, "reaction_10744958": { "compartment": "compartment_7660", "id": "reaction_10744958", "reactome": "R-SPO-4615873", "name": "PIAS2-2 SUMOylates SUZ12 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744943" ], "products": [ "species_10743639", "species_10744956" ], "modifiers": [ [ "species_10743728", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O94522", "SPCC1281.05", "O74792", "SPBC26H8.09c", "SPAC30D11.13", "O13351", "SPBC365.06", "O94522", "SPCC1281.05", "O74792", "SPBC26H8.09c", "SPAC1687.05" ] }, "reaction_10745032": { "compartment": "compartment_7660", "id": "reaction_10745032", "reactome": "R-SPO-4641362", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10745022" ], "products": [ "species_10745030", "species_10743639" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC1703.14c", "P07799", "SPBC1703.14c", "O13351", "SPBC365.06", "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10739546": { "compartment": "compartment_17957", "id": "reaction_10739546", "reactome": "R-SPO-446202", "name": "Addition of the first glucose to the N-glycan precursor by ALG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449371", "species_532542" ], "products": [ "species_449311", "species_449649" ], "modifiers": [ [ "species_10739543", "catalyst" ] ], "additional_components": [ "SPBC342.01c" ] }, "reaction_10740200": { "compartment": "compartment_70101", "id": "reaction_10740200", "reactome": "R-SPO-532549", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_532562" ], "modifiers": [ [ "species_10740197", "catalyst" ] ], "additional_components": [ "SPBC2G2.16" ] }, "reaction_10734722": { "compartment": "compartment_70101", "id": "reaction_10734722", "reactome": "R-SPO-156910", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734718", "species_10734713", "species_10734711" ], "products": [ "species_10734720" ], "modifiers": [], "additional_components": [ "SPAC29A4.02c", "SPCC1450.04", "SPCC1450.04", "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04" ] }, "reaction_10755736": { "compartment": "compartment_70101", "id": "reaction_10755736", "reactome": "R-SPO-8879123", "name": "PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731529", "species_71284" ], "products": [ "species_71285", "species_10755728" ], "modifiers": [ [ "species_10755733", "catalyst" ] ], "additional_components": [ "SPCC576.08c", "SPCC576.08c", "SPBC8D2.10c" ] }, "reaction_10744624": { "compartment": "compartment_7660", "id": "reaction_10744624", "reactome": "R-SPO-3900177", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10730920" ], "products": [ "species_10743639", "species_10744622" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBP8B7.16c", "SPAC30D11.13", "O13351", "SPBC365.06", "P24782", "SPBP8B7.16c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750113": { "compartment": "compartment_70101", "id": "reaction_10750113", "reactome": "R-SPO-6781797", "name": "USP19 binds HIF1A,BIRC2,BIRC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737150", "species_10750109" ], "products": [ "species_10750111" ], "modifiers": [], "additional_components": [ "SPCC962.02c", "SPBC18H10.08c", "O60139", "SPBC18H10.08c", "O14064", "SPCC962.02c" ] }, "reaction_10744889": { "compartment": "compartment_7660", "id": "reaction_10744889", "reactome": "R-SPO-4570496", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732874", "species_10743647" ], "products": [ "species_10743639", "species_10744887" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "P09322", "SPAC1834.03c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750212": { "compartment": "compartment_70101", "id": "reaction_10750212", "reactome": "R-SPO-6781953", "name": "YOD1 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745608", "species_10750208" ], "products": [ "species_10750210" ], "modifiers": [], "additional_components": [ "SPAC1565.08", "SPAC24C9.14", "O13974", "SPAC24C9.14", "Q9P3A7", "SPAC1565.08" ] }, "reaction_10737483": { "compartment": "compartment_70101", "id": "reaction_10737483", "reactome": "R-SPO-204617", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_204628", "species_10737463" ], "products": [ "species_29360", "species_204635", "species_10737473" ], "modifiers": [ [ "species_10737480", "catalyst" ] ], "additional_components": [ "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "O94337", "SPBC1271.04c" ] }, "reaction_10746712": { "compartment": "compartment_70101", "id": "reaction_10746712", "reactome": "R-SPO-5665871", "name": "ADRM1 binds 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729366", "species_10746683" ], "products": [ "species_10746685" ], "modifiers": [], "additional_components": [ "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13", "SPBC342.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10755788": { "compartment": "compartment_70101", "id": "reaction_10755788", "reactome": "R-SPO-8932276", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745608", "species_71284" ], "products": [ "species_71285", "species_10755776" ], "modifiers": [ [ "species_10755785", "catalyst" ] ], "additional_components": [ "SPAC1565.08", "SPAC1565.08", "O13926", "SPAC23C4.06c", "P87241", "SPCC4G3.16" ] }, "reaction_10750092": { "compartment": "compartment_7660", "id": "reaction_10750092", "reactome": "R-SPO-5697009", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10750085" ], "products": [ "species_10750089", "species_10748683" ], "modifiers": [ [ "species_10750085", "catalyst" ] ], "additional_components": [ "P41836", "SPBC23G7.12c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "Q9C0X6", "SPAPB8E5.09", "P25009", "SPBC19F5.01c", "Q9P7V9", "SPBC1703.12", "P41836", "SPBC23G7.12c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "Q9C0X6", "SPAPB8E5.09", "P25009", "SPBC19F5.01c", "Q9P7V9", "SPBC1703.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P41836", "SPBC23G7.12c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "Q9C0X6", "SPAPB8E5.09", "P25009", "SPBC19F5.01c", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10746689": { "compartment": "compartment_70101", "id": "reaction_10746689", "reactome": "R-SPO-5665854", "name": "ADRM1:26S proteaseome binds UCHL5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746685", "species_10746678" ], "products": [ "species_10746687" ], "modifiers": [], "additional_components": [ "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13", "SPBC409.06", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "Q9UUB6", "SPBC409.06", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10734866": { "compartment": "compartment_12045", "id": "reaction_10734866", "reactome": "R-SPO-162798", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_8855659" ], "products": [ "species_8855663", "species_1500596" ], "modifiers": [ [ "species_10734863", "catalyst" ] ], "additional_components": [ "SPBC839.08c" ] }, "reaction_10744744": { "compartment": "compartment_7660", "id": "reaction_10744744", "reactome": "R-SPO-4090284", "name": "SUMOylation of HIPK2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744734", "species_10743647" ], "products": [ "species_10743639", "species_10744742" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC823.03", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "Q9P6P3", "SPAC823.03", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10745739": { "compartment": "compartment_70101", "id": "reaction_10745739", "reactome": "R-SPO-5358494", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745719", "species_71284" ], "products": [ "species_10745706", "species_353106" ], "modifiers": [ [ "species_10745736", "catalyst" ] ], "additional_components": [ "SPAC513.01c", "SPAC513.01c", "Q10206", "SPBC17D1.02", "Q9UT33", "SPAC8F11.02c", "O59713", "SPBC3B8.05" ] }, "reaction_10739520": { "compartment": "compartment_17957", "id": "reaction_10739520", "reactome": "R-SPO-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449312", "species_449229" ], "products": [ "species_449311", "species_449365" ], "modifiers": [ [ "species_10739517", "catalyst" ] ], "additional_components": [ "SPBC1734.12c" ] }, "reaction_10739488": { "compartment": "compartment_17957", "id": "reaction_10739488", "reactome": "R-SPO-446188", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449298", "species_449229" ], "products": [ "species_449311", "species_449315" ], "modifiers": [ [ "species_10739485", "catalyst" ] ], "additional_components": [ "SPAC7D4.06c" ] }, "reaction_10734874": { "compartment": "compartment_12045", "id": "reaction_10734874", "reactome": "R-SPO-162821", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855667", "species_449229" ], "products": [ "species_8855656", "species_162872" ], "modifiers": [ [ "species_10734871", "catalyst" ] ], "additional_components": [ "SPCC16A11.06c" ] }, "reaction_10750032": { "compartment": "compartment_7660", "id": "reaction_10750032", "reactome": "R-SPO-5696605", "name": "USP12, USP26 deubiquitinate AR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750027", "species_113518" ], "products": [ "species_10750029", "species_10748683" ], "modifiers": [ [ "species_10750027", "catalyst" ] ], "additional_components": [ "Q10437", "SPAC12B10.03", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "Q10437", "SPAC12B10.03", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q10437", "SPAC12B10.03", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10745006": { "compartment": "compartment_7660", "id": "reaction_10745006", "reactome": "R-SPO-4641342", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744996", "species_10743647" ], "products": [ "species_10743639", "species_10745004" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPBC1A4.03c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "P08096", "SPBC1A4.03c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10737507": { "compartment": "compartment_70101", "id": "reaction_10737507", "reactome": "R-SPO-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10737463", "species_29368" ], "products": [ "species_29360", "species_10737497", "species_29356" ], "modifiers": [ [ "species_10737504", "catalyst" ] ], "additional_components": [ "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "Q9P6K9", "SPAC30C2.02", "species_113531" ] }, "reaction_10744694": { "compartment": "compartment_7660", "id": "reaction_10744694", "reactome": "R-SPO-4085350", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743639", "species_10743647" ], "products": [ "species_10743639", "species_10744692" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750295": { "compartment": "compartment_7660", "id": "reaction_10750295", "reactome": "R-SPO-6782820", "name": "USP17 deubiquitinates SUDS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10750290" ], "products": [ "species_10750292", "species_10748291" ], "modifiers": [ [ "species_10750290", "catalyst" ] ], "additional_components": [ "O74442", "SPCC1682.12c", "Q9P7M1", "SPBC21C3.02c", "O74442", "SPCC1682.12c", "Q9P7M1", "SPBC21C3.02c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74442", "SPCC1682.12c", "Q9P7M1", "SPBC21C3.02c" ] }, "reaction_10734882": { "compartment": "compartment_70101", "id": "reaction_10734882", "reactome": "R-SPO-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_29416", "species_8855661" ], "modifiers": [ [ "species_10734879", "catalyst" ] ], "additional_components": [ "SPAPB2B4.01c" ] }, "reaction_10748686": { "compartment": "compartment_7660", "id": "reaction_10748686", "reactome": "R-SPO-5689950", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747837" ], "products": [ "species_10748683", "species_10747843" ], "modifiers": [ [ "species_10747837", "catalyst" ] ], "additional_components": [ "Q09879", "SPCC188.08c", "O74503", "SPCC285.17", "O94526", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09879", "SPCC188.08c", "O74503", "SPCC285.17", "O94526", "SPBC609.02", "Q09879", "SPCC188.08c", "O74503", "SPCC285.17", "O94526", "SPBC609.02" ] }, "reaction_10734803": { "compartment": "compartment_12045", "id": "reaction_10734803", "reactome": "R-SPO-162721", "name": "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449299" ], "products": [ "species_162681", "species_29420" ], "modifiers": [ [ "species_10734800", "catalyst" ] ], "additional_components": [ "O94633", "SPBC1677.02", "Q9USW6", "SPBC21B10.11", "O14466", "SPAC31G5.16c" ] }, "reaction_10752208": { "compartment": "compartment_70101", "id": "reaction_10752208", "reactome": "R-SPO-6800138", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10752186" ], "products": [ "species_10752193", "species_71285" ], "modifiers": [ [ "species_10752205", "catalyst" ] ], "additional_components": [ "O74718", "SPCC584.04", "P79063", "SPAC1834.01", "species_29438", "O74718", "SPCC584.04", "P79063", "SPAC1834.01", "species_29438", "Q9UT94", "SPAC323.05c", "Q09723", "SPAC31A2.02" ] }, "reaction_10744991": { "compartment": "compartment_7660", "id": "reaction_10744991", "reactome": "R-SPO-4616015", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744524" ], "products": [ "species_10743639", "species_10744989" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC36.05c", "SPAC30D11.13", "O59702", "SPBC36.05c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744684": { "compartment": "compartment_7660", "id": "reaction_10744684", "reactome": "R-SPO-4085331", "name": "PIAS2-1 SUMOylates PARK7 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744673" ], "products": [ "species_10743639", "species_10744681" ], "modifiers": [ [ "species_10743728", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC22E12.03c", "SPAC30D11.13", "O13351", "SPBC365.06", "Q10356", "SPAC22E12.03c", "SPAC1687.05" ] }, "reaction_10750010": { "compartment": "compartment_70101", "id": "reaction_10750010", "reactome": "R-SPO-5696600", "name": "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750001", "species_29356" ], "products": [ "species_10749260", "species_10750007" ], "modifiers": [ [ "species_10750001", "catalyst" ] ], "additional_components": [ "O94448", "SPAC1687.02", "O74442", "SPCC1682.12c", "P06652", "SPAC24H6.05", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94448", "SPAC1687.02", "O74442", "SPCC1682.12c", "P06652", "SPAC24H6.05", "O94448", "SPAC1687.02", "O74442", "SPCC1682.12c", "P06652", "SPAC24H6.05" ] }, "reaction_10734890": { "compartment": "compartment_12045", "id": "reaction_10734890", "reactome": "R-SPO-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855663", "species_449229" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10734887", "catalyst" ] ], "additional_components": [ "SPAC18B11.05" ] }, "reaction_10739496": { "compartment": "compartment_17957", "id": "reaction_10739496", "reactome": "R-SPO-446189", "name": "Addition of a second glucose to the N-glycan precursor by ALG8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449649", "species_532542" ], "products": [ "species_449311", "species_449638" ], "modifiers": [ [ "species_10739493", "catalyst" ] ], "additional_components": [ "SPAC17C9.07" ] }, "reaction_10739692": { "compartment": "compartment_70101", "id": "reaction_10739692", "reactome": "R-SPO-449734", "name": "Acetylation of glucosamine 6-phosphate to GlcNAc6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449701", "species_76183" ], "products": [ "species_76194", "species_449703" ], "modifiers": [ [ "species_10739689", "catalyst" ] ], "additional_components": [ "O13738", "SPAC16E8.03" ] }, "reaction_10734739": { "compartment": "compartment_70101", "id": "reaction_10734739", "reactome": "R-SPO-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10734735" ], "products": [ "species_10734737" ], "modifiers": [], "additional_components": [ "SPAC513.01c", "O14460", "SPAC513.01c", "species_29438" ] }, "reaction_10734850": { "compartment": "compartment_12045", "id": "reaction_10734850", "reactome": "R-SPO-162742", "name": "(ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855660" ], "products": [ "species_8855660" ], "modifiers": [ [ "species_10734847", "catalyst" ] ], "additional_components": [ "Q09782", "SPAC13G6.03", "Q9Y7P2", "SPCC1450.15" ] }, "reaction_10755240": { "compartment": "compartment_70101", "id": "reaction_10755240", "reactome": "R-SPO-8870466", "name": "RGGT:CHM binds RABs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755236", "species_10755140" ], "products": [ "species_10755238" ], "modifiers": [], "additional_components": [ "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "Q9HDY0", "SPAPB1A10.10c", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O94412", "SPCC1620.05", "species_1131164", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03", "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "O94412", "SPCC1620.05", "Q9HDY0", "SPAPB1A10.10c", "species_1131164", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P46960", "SPAC167.02", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03" ] }, "reaction_10755404": { "compartment": "compartment_70101", "id": "reaction_10755404", "reactome": "R-SPO-8870469", "name": "RGGT geranylgeranylates RAB proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755238", "species_1131164" ], "products": [ "species_111294", "species_10755401", "species_10755399" ], "modifiers": [ [ "species_10755238", "catalyst" ] ], "additional_components": [ "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "O94412", "SPCC1620.05", "Q9HDY0", "SPAPB1A10.10c", "species_1131164", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P46960", "SPAC167.02", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03", "O94412", "SPCC1620.05", "species_1131164", "P46960", "SPAC167.02", "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "Q9HDY0", "SPAPB1A10.10c", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03", "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "O94412", "SPCC1620.05", "Q9HDY0", "SPAPB1A10.10c", "species_1131164", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P46960", "SPAC167.02", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03" ] }, "reaction_10755807": { "compartment": "compartment_70101", "id": "reaction_10755807", "reactome": "R-SPO-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734704", "species_71284" ], "products": [ "species_71285", "species_10755799" ], "modifiers": [ [ "species_10755804", "catalyst" ] ], "additional_components": [ "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "SPBC839.14c" ] }, "reaction_10739597": { "compartment": "compartment_17957", "id": "reaction_10739597", "reactome": "R-SPO-446216", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449365" ], "products": [ "species_449311", "species_449371" ], "modifiers": [ [ "species_10739592", "catalyst" ] ], "additional_components": [ "SPAC1834.05" ] }, "reaction_10734683": { "compartment": "compartment_70101", "id": "reaction_10734683", "reactome": "R-SPO-156823", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734669", "species_10734679" ], "products": [ "species_10734681" ], "modifiers": [], "additional_components": [ "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "O42848", "SPAC23A1.11", "O42991", "SPBC839.13c", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O42848", "SPAC23A1.11", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O42991", "SPBC839.13c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10739605": { "compartment": "compartment_12045", "id": "reaction_10739605", "reactome": "R-SPO-446218", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449293" ], "products": [ "species_449283", "species_29420" ], "modifiers": [ [ "species_10739602", "catalyst" ] ], "additional_components": [ "SPAC23C4.14" ] }, "reaction_10739504": { "compartment": "compartment_12045", "id": "reaction_10739504", "reactome": "R-SPO-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449299", "species_162756" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10739501", "catalyst" ] ], "additional_components": [ "SPBC15D4.04" ] }, "reaction_10739556": { "compartment": "compartment_70101", "id": "reaction_10739556", "reactome": "R-SPO-446204", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532204", "species_29494" ], "products": [ "species_111294", "species_162756" ], "modifiers": [ [ "species_10739553", "catalyst" ] ], "additional_components": [ "O94617", "SPBC1289.08" ] }, "reaction_10739571": { "compartment": "compartment_12045", "id": "reaction_10739571", "reactome": "R-SPO-446207", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449222", "species_162756" ], "products": [ "species_449293", "species_110096" ], "modifiers": [ [ "species_10739568", "catalyst" ] ], "additional_components": [ "O14190", "SPAC56E4.02c", "O14199", "SPAC5D6.06c" ] }, "reaction_10755142": { "compartment": "compartment_70101", "id": "reaction_10755142", "reactome": "R-SPO-8870465", "name": "RGGT binds the RAB-binding subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755132", "species_10755138", "species_1131164" ], "products": [ "species_10755140" ], "modifiers": [], "additional_components": [ "O94412", "SPCC1620.05", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03", "O94412", "SPCC1620.05", "species_1131164", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03" ] }, "reaction_10734858": { "compartment": "compartment_12045", "id": "reaction_10734858", "reactome": "R-SPO-162797", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855656", "species_449229" ], "products": [ "species_8855664" ], "modifiers": [ [ "species_10734855", "catalyst" ] ], "additional_components": [ "SPAC4G8.12c" ] }, "reaction_10744931": { "compartment": "compartment_7660", "id": "reaction_10744931", "reactome": "R-SPO-4615872", "name": "RANBP2 SUMOylates HDAC4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744921" ], "products": [ "species_10743639", "species_10744929" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC800.03", "SPAC30D11.13", "O13351", "SPBC365.06", "P56523", "SPBC800.03", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10739538": { "compartment": "compartment_70101", "id": "reaction_10739538", "reactome": "R-SPO-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10739533", "catalyst" ] ], "additional_components": [ "SPAC1556.07" ] }, "reaction_10744981": { "compartment": "compartment_7660", "id": "reaction_10744981", "reactome": "R-SPO-4615910", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729457", "species_10743647" ], "products": [ "species_10743639", "species_10744979" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPBC16D10.09", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "Q03392", "SPBC16D10.09", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744729": { "compartment": "compartment_7660", "id": "reaction_10744729", "reactome": "R-SPO-4086083", "name": "SUMOylation of ING2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744714", "species_10743647" ], "products": [ "species_10743639", "species_10744727" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10748783": { "compartment": "compartment_7660", "id": "reaction_10748783", "reactome": "R-SPO-5690080", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10748776" ], "products": [ "species_10729044", "species_10748780" ], "modifiers": [ [ "species_10748776", "catalyst" ] ], "additional_components": [ "O74443", "SPCC1682.13", "Q9P7J7", "SPCC24B10.08c", "P04910", "SPAC19G12.06c", "O13719", "SPAC14C4.12c", "P04913", "SPCC622.09", "O60171", "SPBC21H7.02", "Q9UUK2", "SPAC1952.05", "Q09869", "SPAC12G12.05c", "Q9UUD6", "SPBC19C2.04c", "P04909", "SPCC622.08c", "Q9USU8", "SPBC28F2.10c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74443", "SPCC1682.13", "Q9P7J7", "SPCC24B10.08c", "P04910", "SPAC19G12.06c", "O13719", "SPAC14C4.12c", "P04913", "SPCC622.09", "O60171", "SPBC21H7.02", "Q9UUK2", "SPAC1952.05", "Q09869", "SPAC12G12.05c", "Q9UUD6", "SPBC19C2.04c", "P04909", "SPCC622.08c", "Q9USU8", "SPBC28F2.10c", "O74443", "SPCC1682.13", "Q9P7J7", "SPCC24B10.08c", "P04910", "SPAC19G12.06c", "O13719", "SPAC14C4.12c", "P04913", "SPCC622.09", "O60171", "SPBC21H7.02", "Q9UUK2", "SPAC1952.05", "Q09869", "SPAC12G12.05c", "Q9UUD6", "SPBC19C2.04c", "P04909", "SPCC622.08c", "Q9USU8", "SPBC28F2.10c" ] }, "reaction_10747105": { "compartment": "compartment_70101", "id": "reaction_10747105", "reactome": "R-SPO-5676966", "name": "PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5687536", "species_71284" ], "products": [ "species_71285", "species_5687529" ], "modifiers": [ [ "species_10747102", "catalyst" ] ], "additional_components": [ "SPAC869.08" ] }, "reaction_10745717": { "compartment": "compartment_70101", "id": "reaction_10745717", "reactome": "R-SPO-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745706", "species_71284" ], "products": [ "species_71285", "species_10745709" ], "modifiers": [ [ "species_10745714", "catalyst" ] ], "additional_components": [ "SPAC513.01c", "SPAC513.01c", "SPCC576.14" ] }, "reaction_10749267": { "compartment": "compartment_70101", "id": "reaction_10749267", "reactome": "R-SPO-5690152", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749262", "species_29356" ], "products": [ "species_10749264", "species_10729165" ], "modifiers": [ [ "species_10749262", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q11119", "SPBC6B1.06c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q11119", "SPBC6B1.06c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q11119", "SPBC6B1.06c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10734729": { "compartment": "compartment_70101", "id": "reaction_10734729", "reactome": "R-SPO-156913", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10734720", "species_10734724" ], "products": [ "species_10734706", "species_10734726" ], "modifiers": [ [ "species_10734720", "catalyst" ] ], "additional_components": [ "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04", "species_29420", "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "P0CT53", "SPCC794.09c", "species_29438", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "species_29420", "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04", "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04" ] }, "reaction_10745703": { "compartment": "compartment_70101", "id": "reaction_10745703", "reactome": "R-SPO-5358475", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745695", "species_113592", "species_31633" ], "products": [ "species_10734735", "species_111294", "species_76577" ], "modifiers": [ [ "species_10745700", "catalyst" ] ], "additional_components": [ "SPAC513.01c", "SPAC513.01c", "SPBC577.12" ] }, "reaction_10744614": { "compartment": "compartment_7660", "id": "reaction_10744614", "reactome": "R-SPO-3900047", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744604" ], "products": [ "species_10743639", "species_10744612" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBP8B7.16c", "SPAC30D11.13", "O13351", "SPBC365.06", "P24782", "SPBP8B7.16c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10734687": { "compartment": "compartment_70101", "id": "reaction_10734687", "reactome": "R-SPO-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732216" ], "products": [ "species_10734685", "species_10731937" ], "modifiers": [], "additional_components": [ "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "P0C016", "SPAC6G10.11c", "O42706", "SPAC959.08", "P0C8R3", "SPAC589.10c", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O14388", "SPBC685.07c", "Q09668", "SPAC11E3.15", "P52822", "SPAC3H5.12c", "P36584", "SPAPB8E5.06c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P05733", "SPCC1223.05c", "Q9P784", "SPBC1711.06", "O74864", "SPCC18.14c", "O60143", "SPBC18H10.12c", "P0CT77", "SPAC26A3.07c", "P0CT61", "SPCC1322.11", "P79015", "SPAC3H5.10", "P35679", "SPBP8B7.03c", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "O14069", "SPAC1687.06c", "Q09127", "SPBC18E5.04", "P0CT72", "SPBC839.04", "P08094", "SPBP8B7.06", "O94238", "SPAC1805.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "Q9P769", "SPAP7G5.05", "P0CT68", "SPAC3A12.10", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "Q9USR7", "SPBC577.02", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O74904", "SPCC613.05c", "O42699", "SPCC1682.14", "P40372", "SPAC17A5.03", "P0CT83", "SPCC16C4.13c", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07", "Q9US22", "SPAC1783.08c", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "P0C016", "SPAC6G10.11c", "O42706", "SPAC959.08", "P0C8R3", "SPAC589.10c", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "P79071", "SPCC622.18", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O14388", "SPBC685.07c", "Q09668", "SPAC11E3.15", "P52822", "SPAC3H5.12c", "P36584", "SPAPB8E5.06c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P05733", "SPCC1223.05c", "Q9P784", "SPBC1711.06", "O74864", "SPCC18.14c", "O60143", "SPBC18H10.12c", "P0CT77", "SPAC26A3.07c", "P0CT61", "SPCC1322.11", "P79015", "SPAC3H5.10", "P35679", "SPBP8B7.03c", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "O14069", "SPAC1687.06c", "Q09127", "SPBC18E5.04", "P0CT72", "SPBC839.04", "P08094", "SPBP8B7.06", "O94238", "SPAC1805.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "Q9P769", "SPAP7G5.05", "P0CT68", "SPAC3A12.10", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "Q9USR7", "SPBC577.02", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O74904", "SPCC613.05c", "O42699", "SPCC1682.14", "P40372", "SPAC17A5.03", "P0CT83", "SPCC16C4.13c", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07", "Q9US22", "SPAC1783.08c", "O42848", "SPAC23A1.11", "O42991", "SPBC839.13c" ] }, "reaction_10750104": { "compartment": "compartment_70101", "id": "reaction_10750104", "reactome": "R-SPO-6781779", "name": "USP13 deubiquitinates BECN1,USP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750099", "species_29356" ], "products": [ "species_10735397", "species_10750101" ], "modifiers": [ [ "species_10750099", "catalyst" ] ], "additional_components": [ "Q11119", "SPBC6B1.06c", "P87117", "SPAC20G8.10c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q11119", "SPBC6B1.06c", "P87117", "SPAC20G8.10c", "Q11119", "SPBC6B1.06c", "P87117", "SPAC20G8.10c" ] }, "reaction_10734783": { "compartment": "compartment_17957", "id": "reaction_10734783", "reactome": "R-SPO-162683", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_8855661" ], "products": [ "species_76194", "species_8855666" ], "modifiers": [ [ "species_10734780", "catalyst" ] ], "additional_components": [ "SPAC144.10c" ] }, "reaction_10744969": { "compartment": "compartment_7660", "id": "reaction_10744969", "reactome": "R-SPO-4615889", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10741535" ], "products": [ "species_10743639", "species_10744967" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC36.05c", "SPAC30D11.13", "O59702", "SPBC36.05c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10747799": { "compartment": "compartment_70101", "id": "reaction_10747799", "reactome": "R-SPO-5689539", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747795", "species_10746685" ], "products": [ "species_10747797" ], "modifiers": [], "additional_components": [ "SPAC6G9.08", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13", "Q92353", "SPAC6G9.08", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10745017": { "compartment": "compartment_7660", "id": "reaction_10745017", "reactome": "R-SPO-4641345", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10745008" ], "products": [ "species_10743639", "species_10745015" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC1A4.03c", "SPAC30D11.13", "P08096", "SPBC1A4.03c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10749279": { "compartment": "compartment_7660", "id": "reaction_10749279", "reactome": "R-SPO-5690157", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10749274" ], "products": [ "species_10729044", "species_10749276" ], "modifiers": [ [ "species_10749274", "catalyst" ] ], "additional_components": [ "P04910", "SPAC19G12.06c", "Q9P7S5", "SPAC23G3.08c", "P04909", "SPCC622.08c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P04910", "SPAC19G12.06c", "Q9P7S5", "SPAC23G3.08c", "P04909", "SPCC622.08c", "P04910", "SPAC19G12.06c", "Q9P7S5", "SPAC23G3.08c", "P04909", "SPCC622.08c" ] }, "reaction_10755134": { "compartment": "compartment_70101", "id": "reaction_10755134", "reactome": "R-SPO-8870461", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755130", "species_10755128" ], "products": [ "species_10755132" ], "modifiers": [], "additional_components": [ "SPAC167.02", "SPCC1620.05", "O94412", "SPCC1620.05", "P46960", "SPAC167.02" ] }, "reaction_10739595": { "compartment": "compartment_17957", "id": "reaction_10739595", "reactome": "R-SPO-446215", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449315", "species_449229" ], "products": [ "species_449311", "species_449312" ], "modifiers": [ [ "species_10739592", "catalyst" ] ], "additional_components": [ "SPAC1834.05" ] }, "reaction_10755762": { "compartment": "compartment_7660", "id": "reaction_10755762", "reactome": "R-SPO-8932221", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10731070" ], "products": [ "species_10755754", "species_77502" ], "modifiers": [ [ "species_10755759", "catalyst" ] ], "additional_components": [ "SPAC13G7.02c", "SPAC13G7.02c", "SPAC23C4.06c" ] }, "reaction_10739579": { "compartment": "compartment_12045", "id": "reaction_10739579", "reactome": "R-SPO-446208", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449283" ], "products": [ "species_449737", "species_29420" ], "modifiers": [ [ "species_10739576", "catalyst" ] ], "additional_components": [ "SPBC11B10.01" ] }, "reaction_10739682": { "compartment": "compartment_70101", "id": "reaction_10739682", "reactome": "R-SPO-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29512" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10739679", "catalyst" ] ], "additional_components": [ "Q09740", "SPBC12C2.11" ] }, "reaction_10744836": { "compartment": "compartment_13231", "id": "reaction_10744836", "reactome": "R-SPO-4551649", "name": "RANBP2 SUMOylates RANBP2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744823", "species_10743647" ], "products": [ "species_10744833", "species_10743639" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1773.07c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O13351", "SPBC365.06", "Q09717", "SPBC1773.07c", "SPAC30D11.13", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10739480": { "compartment": "compartment_70101", "id": "reaction_10739480", "reactome": "R-SPO-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10739477", "catalyst" ] ], "additional_components": [ "SPAC13C5.05c" ] }, "reaction_10738916": { "compartment": "compartment_70101", "id": "reaction_10738916", "reactome": "R-SPO-426520", "name": "Endonucleolytic RISC hydrolyzes target RNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426523" ], "products": [ "species_426511" ], "modifiers": [ [ "species_10738891", "catalyst" ] ], "additional_components": [ "O74957", "SPCC736.11" ] }, "reaction_10745975": { "compartment": "compartment_70101", "id": "reaction_10745975", "reactome": "R-SPO-5578744", "name": "Importin-8 imports AGO2:miRNA into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745968", "species_10745948" ], "products": [ "species_10745956", "species_10745972" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "P28748", "SPBC1289.03c", "species_29438", "O59809", "SPCC550.11", "O74957", "SPCC736.11", "O74957", "SPCC736.11", "O59809", "SPCC550.11", "P28748", "SPBC1289.03c", "species_29438", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10745966": { "compartment": "compartment_7660", "id": "reaction_10745966", "reactome": "R-SPO-5578742", "name": "AGO1,2:small RNA complexes interact with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745962", "species_10730706", "species_10737547" ], "products": [ "species_10745964" ], "modifiers": [], "additional_components": [ "O74957", "SPCC736.11", "Q02061", "SPAC23G3.01", "P36594", "SPBC28F2.12", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O13877", "SPAC1B3.12c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O14459", "SPACUNK4.06c", "O74825", "SPBC337.14", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "Q02061", "SPAC23G3.01", "P09322", "SPAC1834.03c", "P36595", "SPCC1020.04c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "O74957", "SPCC736.11", "P04909", "SPCC622.08c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P48003", "SPBC11B10.10c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10757019": { "compartment": "compartment_70101", "id": "reaction_10757019", "reactome": "R-SPO-9023909", "name": "C3PO hydrolyzes cleaved passenger strand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757004" ], "products": [ "species_10738889" ], "modifiers": [ [ "species_10757016", "catalyst" ] ], "additional_components": [ "O74957", "SPCC736.11", "O74957", "SPCC736.11", "O74955", "SPCC736.09c", "Q9P7V3", "SPAC30.03c" ] }, "reaction_10745950": { "compartment": "compartment_70101", "id": "reaction_10745950", "reactome": "R-SPO-5578712", "name": "Importin-8 binds AGO2:miRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738887", "species_10745946" ], "products": [ "species_10745948" ], "modifiers": [], "additional_components": [ "O74957", "SPCC736.11", "SPCC550.11", "O59809", "SPCC550.11", "O74957", "SPCC736.11" ] }, "reaction_10757024": { "compartment": "compartment_70101", "id": "reaction_10757024", "reactome": "R-SPO-9023912", "name": "AGO2 cleaves passenger strand of duplex siRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757021" ], "products": [ "species_10757004" ], "modifiers": [ [ "species_10757021", "catalyst" ] ], "additional_components": [ "O74957", "SPCC736.11", "O74957", "SPCC736.11", "O74957", "SPCC736.11" ] }, "reaction_10732342": { "compartment": "compartment_70101", "id": "reaction_10732342", "reactome": "R-SPO-73608", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500829", "species_29356" ], "products": [ "species_31633", "species_500430" ], "modifiers": [ [ "species_10732339", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:15698", "CHEBI:16704", "CHEBI:16450", "Q09190", "SPAC1556.04c", "species_442320" ] }, "reaction_10756398": { "compartment": "compartment_70101", "id": "reaction_10756398", "reactome": "R-SPO-8954327", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10756395", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_418075", "SPCC162.11c" ] }, "reaction_10750462": { "compartment": "compartment_70101", "id": "reaction_10750462", "reactome": "R-SPO-6788295", "name": "HDHD1:Mg2+ dephosphorylates PURIDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788291", "species_29356" ], "products": [ "species_29372", "species_6788290" ], "modifiers": [ [ "species_10750459", "catalyst" ] ], "additional_components": [ "O59760", "SPCC1020.07", "species_29926" ] }, "reaction_10736241": { "compartment": "compartment_70101", "id": "reaction_10736241", "reactome": "R-SPO-193052", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196344" ], "products": [ "species_193055" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10736360": { "compartment": "compartment_70101", "id": "reaction_10736360", "reactome": "R-SPO-196350", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196344" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10746449": { "compartment": "compartment_70101", "id": "reaction_10746449", "reactome": "R-SPO-5652195", "name": "SORD oxidizes D-sorbitol to Fru", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_5652213" ], "products": [ "species_70106", "species_73473", "species_29532" ], "modifiers": [ [ "species_10746446", "catalyst" ] ], "additional_components": [ "species_442320", "P36624", "SPBC1773.05c" ] }, "reaction_10746437": { "compartment": "compartment_70101", "id": "reaction_10746437", "reactome": "R-SPO-5652172", "name": "AKR1B1 reduces Glc to D-sorbitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_70113" ], "products": [ "species_29366", "species_5652213" ], "modifiers": [ [ "species_10736354", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10729667": { "compartment": "compartment_70101", "id": "reaction_10729667", "reactome": "R-SPO-70349", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_30393" ], "products": [ "species_29370", "species_29578" ], "modifiers": [ [ "species_10729664", "catalyst" ] ], "additional_components": [ "O74215", "SPAC977.16c", "species_29926" ] }, "reaction_10753479": { "compartment": "compartment_70101", "id": "reaction_10753479", "reactome": "R-SPO-6813749", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30393", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_6799497" ], "modifiers": [ [ "species_10730487", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10745910": { "compartment": "compartment_7660", "id": "reaction_10745910", "reactome": "R-SPO-5423117", "name": "PHF8 demethylates MeK21-histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10743010" ], "products": [ "species_10732874", "species_159942", "species_159939", "species_29478" ], "modifiers": [ [ "species_10743019", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPCC622.16c" ] }, "reaction_10755942": { "compartment": "compartment_70101", "id": "reaction_10755942", "reactome": "R-SPO-8941895", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733280", "species_10755938" ], "products": [ "species_10755940" ], "modifiers": [], "additional_components": [ "SPBC11B10.09", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10758108": { "compartment": "compartment_7660", "id": "reaction_10758108", "reactome": "R-SPO-9754129", "name": "CDK6 inhibitors bind CDK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9754132", "species_10756021" ], "products": [ "species_10758106" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10426", "P10815", "SPBC582.03", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "LigandDisplayForward?ligandId=7934" ] }, "reaction_10756036": { "compartment": "compartment_7660", "id": "reaction_10756036", "reactome": "R-SPO-8942836", "name": "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10756008" ], "products": [ "species_113582", "species_10756034" ], "modifiers": [ [ "species_10732457", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07" ] }, "reaction_10758118": { "compartment": "compartment_7660", "id": "reaction_10758118", "reactome": "R-SPO-9754130", "name": "CDK4 inhibitors bind CDK4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756032", "species_9754127" ], "products": [ "species_10758116" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "LigandDisplayForward?ligandId=7938", "LigandDisplayForward?ligandId=5950", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "pubchem.compound:9933545", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5680", "LigandDisplayForward?ligandId=7938", "LigandDisplayForward?ligandId=5950", "P36630", "SPAPB2B4.03", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "P10815", "SPBC582.03", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "P04551", "SPBC11B10.09", "pubchem.compound:9933545", "P25009", "SPBC19F5.01c", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5680" ] }, "reaction_10756010": { "compartment": "compartment_13231", "id": "reaction_10756010", "reactome": "R-SPO-8942803", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755982" ], "products": [ "species_10756008" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10733308": { "compartment": "compartment_70101", "id": "reaction_10733308", "reactome": "R-SPO-75849", "name": "Transport of Citrate from Mitochondrial Matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29654", "species_198498" ], "products": [ "species_76190", "species_113544" ], "modifiers": [ [ "species_10733305", "catalyst" ] ], "additional_components": [ "SPAC19G12.05" ] }, "reaction_10733300": { "compartment": "compartment_70101", "id": "reaction_10733300", "reactome": "R-SPO-75848", "name": "ACLY tetramer transforms CIT to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_76190", "species_113592" ], "products": [ "species_29370", "species_76213", "species_29372", "species_76183" ], "modifiers": [ [ "species_10733297", "catalyst" ] ], "additional_components": [ "O13907", "SPAC22A12.16" ] }, "reaction_10736846": { "compartment": "compartment_70101", "id": "reaction_10736846", "reactome": "R-SPO-200555", "name": "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10733319", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "SPAC56E4.04c" ] }, "reaction_10752466": { "compartment": "compartment_70101", "id": "reaction_10752466", "reactome": "R-SPO-6801109", "name": "CHM binds RGGT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752455", "species_10752462" ], "products": [ "species_10752464" ], "modifiers": [], "additional_components": [ "O94412", "SPCC1620.05", "P46960", "SPAC167.02", "SPBC15C4.03", "O94412", "SPCC1620.05", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03" ] }, "reaction_10752457": { "compartment": "compartment_876", "id": "reaction_10752457", "reactome": "R-SPO-6801101", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752448", "species_10752453" ], "products": [ "species_10752455" ], "modifiers": [], "additional_components": [ "SPCC1620.05", "SPAC167.02", "O94412", "SPCC1620.05", "P46960", "SPAC167.02" ] }, "reaction_10746376": { "compartment": "compartment_7660", "id": "reaction_10746376", "reactome": "R-SPO-5651654", "name": "SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10743010" ], "products": [ "species_10746366", "species_77502" ], "modifiers": [ [ "species_10746371", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPCC4B3.12" ] }, "reaction_10746381": { "compartment": "compartment_7660", "id": "reaction_10746381", "reactome": "R-SPO-5651657", "name": "SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746366", "species_77087" ], "products": [ "species_10746379", "species_77502" ], "modifiers": [ [ "species_10746371", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPCC4B3.12" ] }, "reaction_10745162": { "compartment": "compartment_7660", "id": "reaction_10745162", "reactome": "R-SPO-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732874", "species_77087" ], "products": [ "species_10745159", "species_77502" ], "modifiers": [ [ "species_10743825", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPAC890.07c" ] }, "reaction_10746660": { "compartment": "compartment_7660", "id": "reaction_10746660", "reactome": "R-SPO-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745159", "species_77087" ], "products": [ "species_10746658", "species_77502" ], "modifiers": [ [ "species_10743825", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPAC890.07c" ] }, "reaction_10743853": { "compartment": "compartment_7660", "id": "reaction_10743853", "reactome": "R-SPO-3215385", "name": "CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743844" ], "products": [ "species_10743850" ], "modifiers": [ [ "species_10743844", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P78963", "SPBC16H5.11c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P78963", "SPBC16H5.11c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P78963", "SPBC16H5.11c" ] }, "reaction_10745307": { "compartment": "compartment_7660", "id": "reaction_10745307", "reactome": "R-SPO-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10745271" ], "products": [ "species_77502", "species_10745305" ], "modifiers": [ [ "species_10743825", "catalyst" ] ], "additional_components": [ "P04910", "SPAC19G12.06c", "P04909", "SPCC622.08c", "P04910", "SPAC19G12.06c", "P04909", "SPCC622.08c", "SPAC890.07c" ] }, "reaction_10737810": { "compartment": "compartment_70101", "id": "reaction_10737810", "reactome": "R-SPO-350600", "name": "Antizyme inhibitor binds to OAZ and stablizes ODC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737804", "species_10737795" ], "products": [ "species_10737808" ], "modifiers": [], "additional_components": [ "SPAC144.04c", "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c", "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c" ] }, "reaction_10737980": { "compartment": "compartment_70101", "id": "reaction_10737980", "reactome": "R-SPO-353125", "name": "26S proteosome degrades ODC holoenzyme complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737795" ], "products": [ "species_10737789" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c", "SPBC577.14c", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10737797": { "compartment": "compartment_70101", "id": "reaction_10737797", "reactome": "R-SPO-350567", "name": "Antizyme OAZ binds to Ornithine decarboxylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10730038", "species_10737789" ], "products": [ "species_10737795" ], "modifiers": [], "additional_components": [ "SPAC144.04c", "SPBC577.14c", "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c" ] }, "reaction_10752439": { "compartment": "compartment_7660", "id": "reaction_10752439", "reactome": "R-SPO-6800490", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10752434" ], "products": [ "species_113582", "species_10752437" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "SPBC19C7.03", "SPBC19C7.03", "SPCC23B6.03c" ] }, "reaction_10752490": { "compartment": "compartment_17906", "id": "reaction_10752490", "reactome": "R-SPO-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10752485", "catalyst" ] ], "additional_components": [ "Q96VG1", "SPBC119.18", "O59707", "SPBC36.10", "Q9UT07", "SPAP8A3.10" ] }, "reaction_10752443": { "compartment": "compartment_70101", "id": "reaction_10752443", "reactome": "R-SPO-6800793", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752437" ], "products": [ "species_10752441" ], "modifiers": [], "additional_components": [ "SPBC19C7.03", "SPBC19C7.03" ] }, "reaction_10752487": { "compartment": "compartment_17927", "id": "reaction_10752487", "reactome": "R-SPO-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752471", "species_10752483" ], "products": [ "species_10752485" ], "modifiers": [], "additional_components": [ "SPBC119.18", "O59707", "SPBC36.10", "Q9UT07", "SPAP8A3.10", "Q96VG1", "SPBC119.18", "O59707", "SPBC36.10", "Q9UT07", "SPAP8A3.10" ] }, "reaction_10746130": { "compartment": "compartment_70101", "id": "reaction_10746130", "reactome": "R-SPO-5618331", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_10746127" ], "products": [ "species_10738115", "species_76183" ], "modifiers": [ [ "species_10745603", "catalyst" ] ], "additional_components": [ "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "SPBC800.03" ] }, "reaction_10743065": { "compartment": "compartment_20699", "id": "reaction_10743065", "reactome": "R-SPO-2214351", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10743057" ], "products": [ "species_29370", "species_10743062" ], "modifiers": [ [ "species_10743057", "catalyst" ] ], "additional_components": [ "Q10149", "SPAC1D4.02c", "P11620", "SPBC1703.10", "P50528", "SPAC23C11.16", "species_29438", "Q10149", "SPAC1D4.02c", "P11620", "SPBC1703.10", "P50528", "SPAC23C11.16", "species_29438", "Q10149", "SPAC1D4.02c", "P11620", "SPBC1703.10", "P50528", "SPAC23C11.16", "species_29438" ] }, "reaction_10757878": { "compartment": "compartment_17906", "id": "reaction_10757878", "reactome": "R-SPO-9693214", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756754", "species_10757872" ], "products": [ "species_10757876" ], "modifiers": [], "additional_components": [ "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q10056", "SPAC1F5.09c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "P50527", "SPBC1604.14c" ] }, "reaction_10746782": { "compartment": "compartment_70101", "id": "reaction_10746782", "reactome": "R-SPO-5668932", "name": "PAK2 phosphorylates myosin regulatory light chain (MRLC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746773" ], "products": [ "species_29370", "species_10746779" ], "modifiers": [ [ "species_10746316", "catalyst" ] ], "additional_components": [ "Q9USI6", "SPCC645.05c", "Q09196", "SPAP8A3.08", "Q9UUG5", "SPAC926.03", "O14157", "SPAC4A8.05c", "Q9USI6", "SPCC645.05c", "Q09196", "SPAP8A3.08", "Q9UUG5", "SPAC926.03", "O14157", "SPAC4A8.05c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c" ] }, "reaction_10756841": { "compartment": "compartment_876", "id": "reaction_10756841", "reactome": "R-SPO-9013437", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831", "species_29356" ], "products": [ "species_10756817", "species_29372" ], "modifiers": [ [ "species_10756838", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757894": { "compartment": "compartment_876", "id": "reaction_10757894", "reactome": "R-SPO-9693243", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831" ], "products": [ "species_10757892" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10756608": { "compartment": "compartment_7660", "id": "reaction_10756608", "reactome": "R-SPO-9009533", "name": "TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732619", "species_10732432", "species_10756604" ], "products": [ "species_10756606" ], "modifiers": [], "additional_components": [ "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "SPAC3A11.12c", "O43058", "SPBC4C3.12", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "P24782", "SPBP8B7.16c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "CHEBI:27974", "species_193066", "Q9USU9", "SPBC28F2.09", "O43058", "SPBC4C3.12", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "P17871", "SPAC3A11.12c", "species_193132", "P24782", "SPBP8B7.16c", "O74948", "SPCC553.11c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "CHEBI:27974", "species_193066" ] }, "reaction_10756525": { "compartment": "compartment_70101", "id": "reaction_10756525", "reactome": "R-SPO-8981931", "name": "RAC1 and CDC42 activate PAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738343", "species_10738231" ], "products": [ "species_10746302", "species_10738341" ], "modifiers": [], "additional_components": [ "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c" ] }, "reaction_10746286": { "compartment": "compartment_70101", "id": "reaction_10746286", "reactome": "R-SPO-5626469", "name": "GTP-bound RAC1 and CDC42 bind IQGAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746282", "species_10738231" ], "products": [ "species_10746284" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "O14188", "SPAC4F8.13c", "Q01112", "SPAC110.03", "species_29438", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "O14188", "SPAC4F8.13c", "species_29438" ] }, "reaction_10757002": { "compartment": "compartment_7660", "id": "reaction_10757002", "reactome": "R-SPO-9023861", "name": "PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756606", "species_10743825" ], "products": [ "species_10756994" ], "modifiers": [], "additional_components": [ "Q9USU9", "SPBC28F2.09", "O43058", "SPBC4C3.12", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "P17871", "SPAC3A11.12c", "species_193132", "P24782", "SPBP8B7.16c", "O74948", "SPCC553.11c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "CHEBI:27974", "species_193066", "SPAC890.07c", "O43058", "SPBC4C3.12", "P17871", "SPAC3A11.12c", "P24782", "SPBP8B7.16c", "Q9URX7", "SPAC890.07c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "Q9USU9", "SPBC28F2.09", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "O74948", "SPCC553.11c", "CHEBI:27974", "species_193066" ] }, "reaction_10746295": { "compartment": "compartment_876", "id": "reaction_10746295", "reactome": "R-SPO-5626549", "name": "IQGAPs bind CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746284", "species_10737009" ], "products": [ "species_10746290" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "O14188", "SPAC4F8.13c", "species_29438", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "P05933", "SPAC3A12.14", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "species_74016", "O14188", "SPAC4F8.13c", "O14008", "SPAC29A4.05", "species_29438" ] }, "reaction_10756782": { "compartment": "compartment_876", "id": "reaction_10756782", "reactome": "R-SPO-9013158", "name": "CDC42 GDIs block activation of CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756776", "species_10756778" ], "products": [ "species_10756780" ], "modifiers": [], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "O14224", "SPAC6F12.06", "species_29420", "Q01112", "SPAC110.03", "O14224", "SPAC6F12.06" ] }, "reaction_10758013": { "compartment": "compartment_876", "id": "reaction_10758013", "reactome": "R-SPO-9726862", "name": "Phosphorylated RHOU translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758007" ], "products": [ "species_10758011" ], "modifiers": [], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "species_29420", "Q01112", "SPAC110.03" ] }, "reaction_10756867": { "compartment": "compartment_876", "id": "reaction_10756867", "reactome": "R-SPO-9013438", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756855", "species_10756863" ], "products": [ "species_10756865" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "O13995", "SPAC25B8.01", "Q09195", "SPBC16G5.18", "Q10311", "SPAC6C3.08", "O13995", "SPAC25B8.01", "Q09195", "SPBC16G5.18", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "Q10311", "SPAC6C3.08", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10757000": { "compartment": "compartment_7660", "id": "reaction_10757000", "reactome": "R-SPO-9023860", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756996", "species_10756988" ], "products": [ "species_10756998" ], "modifiers": [], "additional_components": [ "O43058", "SPBC4C3.12", "P17871", "SPAC3A11.12c", "P24782", "SPBP8B7.16c", "Q9URX7", "SPAC890.07c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "Q9USU9", "SPBC28F2.09", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "O74948", "SPCC553.11c", "CHEBI:27974", "species_193066", "Q10325", "SPAC17G8.13c", "Q9UUK2", "SPAC1952.05", "O43058", "SPBC4C3.12", "Q10325", "SPAC17G8.13c", "P17871", "SPAC3A11.12c", "P24782", "SPBP8B7.16c", "Q9URX7", "SPAC890.07c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "Q9USU9", "SPBC28F2.09", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "O74948", "SPCC553.11c", "Q9UUK2", "SPAC1952.05", "CHEBI:27974", "species_193066" ] }, "reaction_10756484": { "compartment": "compartment_70101", "id": "reaction_10756484", "reactome": "R-SPO-8980691", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10734490" ], "products": [ "species_10734492", "species_29420" ], "modifiers": [ [ "species_10738645", "catalyst" ] ], "additional_components": [ "species_29420", "Q09914", "SPAC1F7.04", "Q09914", "SPAC1F7.04", "species_29438", "Q9USU1", "SPBC336.03", "P26674", "SPCC1442.01" ] }, "reaction_10746292": { "compartment": "compartment_70101", "id": "reaction_10746292", "reactome": "R-SPO-5626507", "name": "IQGAPs bind F-actin, which is inhibited by calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746284", "species_10742720" ], "products": [ "species_10746288" ], "modifiers": [ [ "species_10746290", "inhibitor" ] ], "additional_components": [ "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "O14188", "SPAC4F8.13c", "species_29438", "species_113592", "O60054", "SPBC56F2.03", "P10989", "SPBC32H8.12c", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "species_113592", "O60054", "SPBC56F2.03", "O14188", "SPAC4F8.13c", "P10989", "SPBC32H8.12c", "species_29438", "P05933", "SPAC3A12.14", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "species_74016", "O14188", "SPAC4F8.13c", "O14008", "SPAC29A4.05", "species_29438" ] }, "reaction_10756869": { "compartment": "compartment_876", "id": "reaction_10756869", "reactome": "R-SPO-9013452", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831" ], "products": [ "species_10756855" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10756701": { "compartment": "compartment_876", "id": "reaction_10756701", "reactome": "R-SPO-9013009", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734492", "species_10756697" ], "products": [ "species_10756699" ], "modifiers": [], "additional_components": [ "Q09914", "SPAC1F7.04", "species_29438", "O74534", "SPCC74.01", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O43027", "SPBC354.13", "O74498", "SPCC285.11", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "P36583", "SPBC12D12.04c", "O14188", "SPAC4F8.13c", "O74786", "SPBC26H8.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c", "O74534", "SPCC74.01", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O43027", "SPBC354.13", "species_29438", "O74498", "SPCC285.11", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "P36583", "SPBC12D12.04c", "O14188", "SPAC4F8.13c", "O74786", "SPBC26H8.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c" ] }, "reaction_10757843": { "compartment": "compartment_876", "id": "reaction_10757843", "reactome": "R-SPO-9692800", "name": "CDC42 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738231" ], "products": [ "species_10757841" ], "modifiers": [], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "Q01112", "SPAC110.03", "species_29438" ] }, "reaction_10756625": { "compartment": "compartment_7660", "id": "reaction_10756625", "reactome": "R-SPO-9011949", "name": "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756620" ], "products": [ "species_10747338", "species_10756622" ], "modifiers": [ [ "species_10756620", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "O94691", "SPBC83.07", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "CHEBI:50114", "SPBC83.07", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "CHEBI:50114", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "O94691", "SPBC83.07", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "CHEBI:50114" ] }, "reaction_10756686": { "compartment": "compartment_876", "id": "reaction_10756686", "reactome": "R-SPO-9013006", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734492" ], "products": [ "species_10756684" ], "modifiers": [], "additional_components": [ "Q09914", "SPAC1F7.04", "species_29438", "Q09914", "SPAC1F7.04", "species_29438" ] }, "reaction_10756523": { "compartment": "compartment_70101", "id": "reaction_10756523", "reactome": "R-SPO-8981926", "name": "RAC1 and CDC42 activate PAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738231", "species_10738347" ], "products": [ "species_10746304", "species_10738345" ], "modifiers": [], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "SPBC1604.14c" ] }, "reaction_10756658": { "compartment": "compartment_7660", "id": "reaction_10756658", "reactome": "R-SPO-9012319", "name": "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10756653" ], "products": [ "species_113582", "species_10756655" ], "modifiers": [ [ "species_10756653", "catalyst" ] ], "additional_components": [ "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O14098", "SPAC2F3.15", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "CHEBI:50114", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O59748", "SPBC530.13", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O14098", "SPAC2F3.15", "O13877", "SPAC1B3.12c", "CHEBI:50114", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O59748", "SPBC530.13", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O14098", "SPAC2F3.15", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "CHEBI:50114", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O59748", "SPBC530.13", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10756519": { "compartment": "compartment_70101", "id": "reaction_10756519", "reactome": "R-SPO-8981637", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734492", "species_29356" ], "products": [ "species_29372", "species_10734490" ], "modifiers": [ [ "species_10756516", "catalyst" ] ], "additional_components": [ "Q09914", "SPAC1F7.04", "species_29438", "species_29420", "Q09914", "SPAC1F7.04", "O74335", "SPBC17F3.01c", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757377": { "compartment": "compartment_70101", "id": "reaction_10757377", "reactome": "R-SPO-9626816", "name": "PIN1 binds p-S345-NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757370", "species_10757372" ], "products": [ "species_10757374" ], "modifiers": [ [ "species_10757372", "catalyst" ] ], "additional_components": [ "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "SPCC16C4.03", "O74448", "SPCC16C4.03", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "SPCC16C4.03" ] }, "reaction_10746044": { "compartment": "compartment_5263232", "id": "reaction_10746044", "reactome": "R-SPO-5610749", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10746040" ], "products": [ "species_10746034", "species_10746042" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "P40376", "SPBC106.10", "SPBC106.10", "P36600", "SPAC8C9.03", "species_30389" ] }, "reaction_10756834": { "compartment": "compartment_876", "id": "reaction_10756834", "reactome": "R-SPO-9013435", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756817" ], "products": [ "species_10756831", "species_29420" ], "modifiers": [ [ "species_10756817", "catalyst" ] ], "additional_components": [ "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01" ] }, "reaction_10756918": { "compartment": "compartment_876", "id": "reaction_10756918", "reactome": "R-SPO-9018768", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756915" ], "products": [ "species_10756895", "species_29420" ], "modifiers": [ [ "species_10756915", "catalyst" ] ], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "Q01112", "SPAC110.03", "species_29438", "species_29420", "Q01112", "SPAC110.03" ] }, "reaction_10756793": { "compartment": "compartment_876", "id": "reaction_10756793", "reactome": "R-SPO-9013159", "name": "CDC42 GEFs activate CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756776" ], "products": [ "species_29420", "species_10738231" ], "modifiers": [ [ "species_10756790", "catalyst" ] ], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "Q01112", "SPAC110.03", "species_29438", "Q09763", "SPAC24H6.09", "O59679", "SPBC29A3.17", "Q9USU1", "SPBC336.03", "Q9HGL2", "SPBC800.10c", "P26674", "SPCC1442.01", "Q04665", "SPAC23H3.13c" ] }, "reaction_10745852": { "compartment": "compartment_12045", "id": "reaction_10745852", "reactome": "R-SPO-5362412", "name": "SYVN1 ubiquitinates Hh C-terminal fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745845", "species_10729165" ], "products": [ "species_10745849" ], "modifiers": [ [ "species_10745845", "catalyst" ] ], "additional_components": [ "O13875", "SPAC1B3.10c", "Q9UTC8", "SPAC227.11c", "Q9P3A7", "SPAC1565.08", "O74757", "SPBC17D11.02c", "O94458", "SPAC1687.17c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9UTC8", "SPAC227.11c", "O13875", "SPAC1B3.10c", "Q9P3A7", "SPAC1565.08", "O74757", "SPBC17D11.02c", "O94458", "SPAC1687.17c", "O13875", "SPAC1B3.10c", "Q9UTC8", "SPAC227.11c", "Q9P3A7", "SPAC1565.08", "O74757", "SPBC17D11.02c", "O94458", "SPAC1687.17c" ] }, "reaction_10756682": { "compartment": "compartment_70101", "id": "reaction_10756682", "reactome": "R-SPO-9012835", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756678", "species_10734490" ], "products": [ "species_10756680" ], "modifiers": [], "additional_components": [ "O14224", "SPAC6F12.06", "species_29420", "Q09914", "SPAC1F7.04", "species_29420", "Q09914", "SPAC1F7.04", "O14224", "SPAC6F12.06" ] }, "reaction_10757858": { "compartment": "compartment_70101", "id": "reaction_10757858", "reactome": "R-SPO-9693198", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831", "species_10757854" ], "products": [ "species_10757856" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "O94655", "SPBC405.04c", "Q9HGP5", "SPAC631.01c", "Q10056", "SPAC1F5.09c", "O13728", "SPAC15A10.08", "Q92356", "SPAC6G9.11", "Q9P7E8", "SPAPJ760.02c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c", "Q7LKY2", "SPBC1289.14", "P50527", "SPBC1604.14c", "O13728", "SPAC15A10.08", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "O43027", "SPBC354.13", "Q10133", "SPAC16.01", "species_29438", "Q9P3B1", "SPAC1565.02c", "Q7LKY2", "SPBC1289.14", "P50527", "SPBC1604.14c", "O94655", "SPBC405.04c", "Q9HGP5", "SPAC631.01c", "Q10056", "SPAC1F5.09c", "Q9HE04", "SPAC20H4.11c", "O13928", "SPAC23C4.08", "Q9P7E8", "SPAPJ760.02c", "Q874R1", "SPAC16A10.04" ] }, "reaction_10751276": { "compartment": "compartment_1222693", "id": "reaction_10751276", "reactome": "R-SPO-6798174", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524165" ], "products": [ "species_29370", "species_1629751" ], "modifiers": [ [ "species_10751273", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05" ] }, "reaction_10756913": { "compartment": "compartment_876", "id": "reaction_10756913", "reactome": "R-SPO-9018766", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756895", "species_10756909" ], "products": [ "species_10756911" ], "modifiers": [], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "Q9USZ0", "SPBC1306.02", "O74749", "SPBC1734.08", "Q9USR1", "SPBC577.08c", "O13728", "SPAC15A10.08", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "Q92462", "SPAC11G7.02", "O94478", "SPCC1919.11", "P50527", "SPBC1604.14c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "Q9UTG2", "SPAC1805.15c", "O14188", "SPAC4F8.13c", "O94685", "SPBC83.01", "O14326", "SPBC16E9.11c", "Q9USZ0", "SPBC1306.02", "O74749", "SPBC1734.08", "Q9USR1", "SPBC577.08c", "O13728", "SPAC15A10.08", "Q9HGL2", "SPBC800.10c", "species_29438", "Q10172", "SPAC25G10.09c", "Q92462", "SPAC11G7.02", "O94478", "SPCC1919.11", "P50527", "SPBC1604.14c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "Q9UTG2", "SPAC1805.15c", "O14188", "SPAC4F8.13c", "O94685", "SPBC83.01", "O14326", "SPBC16E9.11c" ] }, "reaction_10757398": { "compartment": "compartment_70101", "id": "reaction_10757398", "reactome": "R-SPO-9626880", "name": "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757392", "species_113592" ], "products": [ "species_29370", "species_10757370" ], "modifiers": [ [ "species_10739926", "catalyst" ] ], "additional_components": [ "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "SPAC24B11.06c" ] }, "reaction_10756800": { "compartment": "compartment_876", "id": "reaction_10756800", "reactome": "R-SPO-9013161", "name": "CDC42 GAPs stimulate CDC42 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10738231" ], "products": [ "species_10756776", "species_29372" ], "modifiers": [ [ "species_10756797", "catalyst" ] ], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "species_29420", "Q01112", "SPAC110.03", "O74335", "SPBC17F3.01c", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757395": { "compartment": "compartment_70101", "id": "reaction_10757395", "reactome": "R-SPO-9626832", "name": "MAPK1 or MAPK3 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757392", "species_113592" ], "products": [ "species_29370", "species_10757370" ], "modifiers": [ [ "species_10744304", "catalyst" ] ], "additional_components": [ "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10757874": { "compartment": "compartment_876", "id": "reaction_10757874", "reactome": "R-SPO-9693207", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831" ], "products": [ "species_10757872" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10757388": { "compartment": "compartment_70101", "id": "reaction_10757388", "reactome": "R-SPO-9626817", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10757374" ], "products": [ "species_29370", "species_10757386" ], "modifiers": [ [ "species_10745378", "catalyst" ] ], "additional_components": [ "O74448", "SPCC16C4.03", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "O74448", "SPCC16C4.03", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10749638": { "compartment": "compartment_12045", "id": "reaction_10749638", "reactome": "R-SPO-5693761", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_428256" ], "products": [ "species_5693768", "species_29356" ], "modifiers": [ [ "species_10749635", "catalyst" ] ], "additional_components": [ "SPAC19G12.08" ] }, "reaction_10739067": { "compartment": "compartment_70101", "id": "reaction_10739067", "reactome": "R-SPO-428664", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275", "species_29356" ], "products": [ "species_428694", "species_29372" ], "modifiers": [ [ "species_10739064", "catalyst" ] ], "additional_components": [ "Q9P6N5", "SPAC823.11" ] }, "reaction_10739084": { "compartment": "compartment_70101", "id": "reaction_10739084", "reactome": "R-SPO-428701", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10739064", "catalyst" ] ], "additional_components": [ "Q9P6N5", "SPAC823.11" ] }, "reaction_10739049": { "compartment": "compartment_70101", "id": "reaction_10739049", "reactome": "R-SPO-428259", "name": "dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_428206", "species_29368", "species_428126" ], "products": [ "species_29356", "species_428218", "species_428256" ], "modifiers": [ [ "species_10739046", "catalyst" ] ], "additional_components": [ "species_29364", "species_29362", "species_29366", "species_113526", "SPBC3B8.07c" ] }, "reaction_10739027": { "compartment": "compartment_70101", "id": "reaction_10739027", "reactome": "R-SPO-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_428139" ], "products": [ "species_76194", "species_428126" ], "modifiers": [ [ "species_10739024", "catalyst" ] ], "additional_components": [ "O59735", "SPBC3E7.15c", "P78970", "SPAC1A6.09c" ] }, "reaction_10739055": { "compartment": "compartment_70101", "id": "reaction_10739055", "reactome": "R-SPO-428273", "name": "SPHK1 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10738404", "catalyst" ] ], "additional_components": [ "SPAC4A8.07c" ] }, "reaction_10739041": { "compartment": "compartment_70101", "id": "reaction_10739041", "reactome": "R-SPO-428214", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_113592" ], "products": [ "species_29370", "species_428275" ], "modifiers": [ [ "species_10739038", "catalyst" ] ], "additional_components": [ "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04" ] }, "reaction_10739052": { "compartment": "compartment_70101", "id": "reaction_10739052", "reactome": "R-SPO-428260", "name": "dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_428126" ], "products": [ "species_29366", "species_9025544", "species_29356" ], "modifiers": [ [ "species_10739046", "catalyst" ] ], "additional_components": [ "SPBC3B8.07c" ] }, "reaction_10757901": { "compartment": "compartment_70101", "id": "reaction_10757901", "reactome": "R-SPO-9695949", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10739036", "catalyst" ], [ "species_10757899", "inhibitor" ] ], "additional_components": [ "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04", "LigandDisplayForward?ligandId=6625", "LigandDisplayForward?ligandId=10641", "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04", "LigandDisplayForward?ligandId=10219", "LigandDisplayForward?ligandId=6624" ] }, "reaction_10739081": { "compartment": "compartment_70101", "id": "reaction_10739081", "reactome": "R-SPO-428696", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10739072", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10739075": { "compartment": "compartment_984", "id": "reaction_10739075", "reactome": "R-SPO-428690", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_109276" ], "products": [ "species_109277", "species_428662" ], "modifiers": [ [ "species_10739072", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10740345": { "compartment": "compartment_70101", "id": "reaction_10740345", "reactome": "R-SPO-879459", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740341", "species_10740336" ], "products": [ "species_10740343" ], "modifiers": [], "additional_components": [ "SPAC631.01c", "SPAC12B10.07", "Q9HGP5", "SPAC631.01c", "Q10434", "SPAC12B10.07" ] }, "reaction_10741463": { "compartment": "compartment_7660", "id": "reaction_10741463", "reactome": "R-SPO-994106", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741456", "species_10741459" ], "products": [ "species_10741461" ], "modifiers": [], "additional_components": [ "SPAC664.01c", "SPAC1834.04", "P09988", "SPAC1834.04", "P40381", "SPAC664.01c" ] }, "reaction_10741481": { "compartment": "compartment_74700", "id": "reaction_10741481", "reactome": "R-SPO-1011576", "name": "EHD proteins interact with Rabenosyn-5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741477", "species_10741468" ], "products": [ "species_10741479" ], "modifiers": [], "additional_components": [ "SPAC17G6.08", "SPAC16E8.01", "O13786", "SPAC17G6.08", "O13736", "SPAC16E8.01" ] }, "reaction_10741454": { "compartment": "compartment_70101", "id": "reaction_10741454", "reactome": "R-SPO-992708", "name": "Dual-specific AKAPs bind type I and II PKA regulatory subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734228", "species_10741450" ], "products": [ "species_10741452" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "P40376", "SPBC106.10", "SPAC23G3.05c", "Q9P7S8", "SPAC23G3.05c", "P36600", "SPAC8C9.03", "P40376", "SPBC106.10" ] }, "reaction_10741445": { "compartment": "compartment_17906", "id": "reaction_10741445", "reactome": "R-SPO-992703", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741439" ], "products": [ "species_10741443" ], "modifiers": [], "additional_components": [ "SPBC1706.03", "Q9USY7", "SPBC1706.03" ] }, "reaction_10750893": { "compartment": "compartment_7660", "id": "reaction_10750893", "reactome": "R-SPO-6791222", "name": "21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750858" ], "products": [ "species_10750866" ], "modifiers": [ [ "species_10750890", "catalyst" ], [ "species_10750562", "catalyst" ], [ "species_10750878", "catalyst" ], [ "species_10750574", "catalyst" ] ], "additional_components": [ "O59675", "SPBC29A3.12", "Q9HDY4", "SPAPB1A10.06c", "O60055", "SPBC56F2.04", "Q9USN3", "SPCC16A11.02", "O94365", "SPBC428.19c", "O60179", "SPBC23E6.04c", "Q09775", "SPAC22F3.08c", "O74340", "SPBC1A4.07c", "O60161", "SPBC19F5.02c", "Q9P6P2", "SPAC823.04", "P35551", "SPBC2D10.10c", "O60188", "SPBC244.02c", "Q10107", "SPAC18G6.07c", "O74835", "SPCC1183.07", "Q9C1X1", "SPBC713.04c", "Q10101", "SPAC18G6.14c", "Q10106", "SPAC18G6.06", "P0CT56", "SPAC3H5.05c", "P78750", "SPBC29A3.06", "O74690", "SPAC607.03c", "Q9P6N8", "SPAC823.08c", "O94683", "SPBC776.17", "O94676", "SPBC776.08c", "O94653", "SPBC31E1.06", "O13835", "SPAC19D5.05c", "Q9HE11", "SPAC20H4.01", "O13823", "SPAC19A8.07c", "P0CT57", "SPBC18H10.13", "Q9P4X3", "SPAC959.03c", "O14053", "SPCC1672.07", "P87137", "SPAC57A7.06", "O94372", "SPBC1604.06c", "O43051", "SPBC3F6.04c", "O94514", "SPBC646.10c", "Q9P7S7", "SPAC23G3.06", "O74974", "SPCC1827.01c", "Q09757", "SPAC24H6.07", "O13610", "SPBC32H8.04c", "O74777", "SPBC25B2.05", "Q1MTS0", "SPBC3B8.09", "O13878", "SPAC1B3.13", "O13910", "SPAC23C11.03", "Q9P7C0", "SPAC2E1P5.05", "Q09870", "SPAC12G12.06c", "O74892", "SPCC576.08c", "Q9HGM5", "SPBC543.06c", "P87177", "SPBC3D6.12", "Q9C0Z7", "SPAPB1E7.12", "O59675", "SPBC29A3.12", "Q9HDY4", "SPAPB1A10.06c", "O60055", "SPBC56F2.04", "Q9USN3", "SPCC16A11.02", "O94365", "SPBC428.19c", "O60179", "SPBC23E6.04c", "Q09775", "SPAC22F3.08c", "O74340", "SPBC1A4.07c", "O60161", "SPBC19F5.02c", "Q9P6P2", "SPAC823.04", "P35551", "SPBC2D10.10c", "O60188", "SPBC244.02c", "Q10107", "SPAC18G6.07c", "O74835", "SPCC1183.07", "Q9C1X1", "SPBC713.04c", "Q10101", "SPAC18G6.14c", "Q10106", "SPAC18G6.06", "P0CT56", "SPAC3H5.05c", "P78750", "SPBC29A3.06", "O74690", "SPAC607.03c", "Q9P6N8", "SPAC823.08c", "O94683", "SPBC776.17", "O94676", "SPBC776.08c", "O94653", "SPBC31E1.06", "O13835", "SPAC19D5.05c", "Q9HE11", "SPAC20H4.01", "O13823", "SPAC19A8.07c", "P0CT57", "SPBC18H10.13", "Q9P4X3", "SPAC959.03c", "O14053", "SPCC1672.07", "P87137", "SPAC57A7.06", "O94372", "SPBC1604.06c", "O43051", "SPBC3F6.04c", "O94514", "SPBC646.10c", "Q9P7S7", "SPAC23G3.06", "O74974", "SPCC1827.01c", "Q09757", "SPAC24H6.07", "O13610", "SPBC32H8.04c", "O74777", "SPBC25B2.05", "Q1MTS0", "SPBC3B8.09", "O13878", "SPAC1B3.13", "O13910", "SPAC23C11.03", "Q9P7C0", "SPAC2E1P5.05", "Q09870", "SPAC12G12.06c", "O74892", "SPCC576.08c", "Q9HGM5", "SPBC543.06c", "P87177", "SPBC3D6.12", "Q9C0Z7", "SPAPB1E7.12", "O14232", "SPAC6F12.16c", "O74918", "SPCC757.08", "O60124", "SPBC16G5.10", "O42872", "SPAC3G9.10c", "O74469", "SPCC1739.07", "Q10146", "SPAC1F3.01", "Q9P7R3", "SPBC211.08c", "O59821", "SPCC1840.11", "Q09704", "SPAC2F7.14c", "O14076", "SPACUNK4.11c", "O42894", "SPBC115.01c", "Q10205", "SPBC17D1.03c", "O13903", "SPAC22A12.12c", "SPAC6F12.16c", "SPBC115.01c", "SPAC1F3.01" ] }, "reaction_10751111": { "compartment": "compartment_70101", "id": "reaction_10751111", "reactome": "R-SPO-6791223", "name": "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751081", "species_10751079" ], "products": [ "species_10751095", "species_10751085", "species_10751089", "species_10751103", "species_10751083", "species_10751087", "species_10751081", "species_10751093", "species_10751097", "species_10751091", "species_10731692" ], "modifiers": [ [ "species_10751087", "catalyst" ], [ "species_10751097", "catalyst" ], [ "species_10751109", "catalyst" ], [ "species_10751103", "catalyst" ] ], "additional_components": [ "SPAC10F6.10", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "Q10312", "SPAC6C3.09", "P40236", "SPAC23C4.12", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "P87120", "SPAC3A12.04c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9P7W5", "SPBC1703.05", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P40235", "SPBC3H7.15", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O60071", "SPBC13G1.09", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "Q9UTK0", "SPAC1486.09", "O94715", "SPCC1393.03", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "Q9Y813", "SPBC1105.16c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "Q10191", "SPAC3F10.17", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "O14044", "SPAC2C4.11c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "O13956", "SPAC23H4.15", "Q9UTQ6", "SPAC1071.07c", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "O42650", "SPAC10F6.10", "SPAC10F6.10", "SPAC3F10.17", "SPAC2C4.11c", "P40235", "SPBC3H7.15", "P40236", "SPAC23C4.12", "SPBC13G1.09", "SPAC1486.09", "SPAC10F6.10", "SPAC23H4.15", "SPBC3H7.15", "SPBC1703.05", "O59675", "SPBC29A3.12", "Q9P7B2", "SPAC521.05", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P0CT74", "SPAC144.11", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P87158", "SPBC19F8.08", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0CT76", "SPBP4H10.13", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT80", "SPCC285.15c", "P0CT64", "SPBC18H10.14", "Q9UTG4", "SPAC1805.11c", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "P0CT58", "SPAC22A12.04c", "O13614", "SPBP22H7.08", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q9UTQ6", "SPAC1071.07c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "Q9P4W9", "SPAC959.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "O74172", "SPBC3D6.15", "P0CT66", "SPBC16D10.11c", "SPAC1486.09", "SPBC3H7.15", "SPAC26A3.06", "P40235", "SPBC3H7.15", "P40236", "SPAC23C4.12" ] }, "reaction_10750611": { "compartment": "compartment_7660", "id": "reaction_10750611", "reactome": "R-SPO-6791219", "name": "32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750595" ], "products": [ "species_10750552" ], "modifiers": [ [ "species_10750593", "catalyst" ], [ "species_10750543", "catalyst" ], [ "species_10750609", "catalyst" ], [ "species_10750548", "catalyst" ] ], "additional_components": [ "Q9UU96", "SPCC830.03", "O42936", "SPBC16C6.12c", "Q9URY0", "SPAC890.04c", "O74399", "SPBC4F6.13c", "O94718", "SPCC1393.06c", "P87243", "SPCC4G3.18", "O42957", "SPBC19G7.09", "Q10272", "SPAC13G7.08c", "O60164", "SPBC19F5.05c", "Q9UU96", "SPCC830.03", "O42936", "SPBC16C6.12c", "O94718", "SPCC1393.06c", "P87243", "SPCC4G3.18", "O42957", "SPBC19G7.09", "Q10272", "SPAC13G7.08c", "Q9URY0", "SPAC890.04c", "O74399", "SPBC4F6.13c", "O60164", "SPBC19F5.05c", "SPBC16C6.12c", "O13802", "SPAC17H9.05", "O74791", "SPBC26H8.08c", "O60164", "SPBC19F5.05c", "SPCC830.03" ] }, "reaction_10732544": { "compartment": "compartment_70101", "id": "reaction_10732544", "reactome": "R-SPO-73798", "name": "AICAR + 10-Formyl-THF => FAICAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111409", "species_419151" ], "products": [ "species_111427", "species_111355" ], "modifiers": [ [ "species_10732538", "catalyst" ] ], "additional_components": [ "O74928", "SPCPB16A4.03c" ] }, "reaction_10757804": { "compartment": "compartment_70101", "id": "reaction_10757804", "reactome": "R-SPO-9678749", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732525", "species_9678719" ], "products": [ "species_10732528" ], "modifiers": [], "additional_components": [ "O14344", "SPBC2F12.14c", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "O14344", "SPBC2F12.14c", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842" ] }, "reaction_10732518": { "compartment": "compartment_70101", "id": "reaction_10732518", "reactome": "R-SPO-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111584", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29404", "species_111294", "species_76577", "species_113578" ], "modifiers": [ [ "species_10732515", "catalyst" ] ], "additional_components": [ "SPBC2F12.14c" ] }, "reaction_10732530": { "compartment": "compartment_70101", "id": "reaction_10732530", "reactome": "R-SPO-73794", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_111584" ], "modifiers": [ [ "species_10732525", "catalyst" ], [ "species_10732528", "inhibitor" ], [ "species_111584", "inhibitor" ] ], "additional_components": [ "O14344", "SPBC2F12.14c", "O14344", "SPBC2F12.14c", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842" ] }, "reaction_10734091": { "compartment": "compartment_70101", "id": "reaction_10734091", "reactome": "R-SPO-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29438", "species_29448" ], "products": [ "species_70106", "species_35141", "species_29372", "species_29420" ], "modifiers": [ [ "species_10734088", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_113578", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_30014", "inhibitor" ] ], "additional_components": [ "Q02787", "SPAC144.03", "species_29926" ] }, "reaction_10732576": { "compartment": "compartment_70101", "id": "reaction_10732576", "reactome": "R-SPO-73814", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_113592", "species_111292" ], "products": [ "species_70106", "species_29370", "species_111338", "species_29372" ], "modifiers": [ [ "species_10732559", "catalyst" ] ], "additional_components": [ "SPBC405.01" ] }, "reaction_10732570": { "compartment": "compartment_70101", "id": "reaction_10732570", "reactome": "R-SPO-73812", "name": "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111354", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29370", "species_111369", "species_29404", "species_29372" ], "modifiers": [ [ "species_10732567", "catalyst" ] ], "additional_components": [ "SPAC6F12.10c" ] }, "reaction_10732573": { "compartment": "compartment_70101", "id": "reaction_10732573", "reactome": "R-SPO-73813", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111338", "species_419151" ], "products": [ "species_70106", "species_111354", "species_111355" ], "modifiers": [ [ "species_10732559", "catalyst" ] ], "additional_components": [ "SPBC405.01" ] }, "reaction_10732541": { "compartment": "compartment_70101", "id": "reaction_10732541", "reactome": "R-SPO-73797", "name": "FAICAR => IMP + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111427" ], "products": [ "species_29602", "species_29356" ], "modifiers": [ [ "species_10732538", "catalyst" ] ], "additional_components": [ "O74928", "SPCPB16A4.03c" ] }, "reaction_10732554": { "compartment": "compartment_70101", "id": "reaction_10732554", "reactome": "R-SPO-73800", "name": "SAICAR => AICAR + Fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111399" ], "products": [ "species_29586", "species_111409" ], "modifiers": [ [ "species_10732551", "catalyst" ] ], "additional_components": [ "O60105", "SPBC14F5.09c" ] }, "reaction_10732578": { "compartment": "compartment_70101", "id": "reaction_10732578", "reactome": "R-SPO-73828", "name": "adenylosuccinate => adenosine 5'-monophosphate + fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_35141" ], "products": [ "species_29586", "species_76577" ], "modifiers": [ [ "species_10732551", "catalyst" ] ], "additional_components": [ "O60105", "SPBC14F5.09c" ] }, "reaction_10732562": { "compartment": "compartment_70101", "id": "reaction_10732562", "reactome": "R-SPO-73810", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111369" ], "products": [ "species_70106", "species_29370", "species_111370", "species_29372" ], "modifiers": [ [ "species_10732559", "catalyst" ] ], "additional_components": [ "SPBC405.01" ] }, "reaction_10739670": { "compartment": "compartment_7660", "id": "reaction_10739670", "reactome": "R-SPO-448955", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10739644", "species_10739654" ], "products": [ "species_113582", "species_10739667" ], "modifiers": [ [ "species_10739654", "catalyst" ] ], "additional_components": [ "SPBC317.01", "Q09892", "SPAC24B11.06c", "Q09892", "SPAC24B11.06c", "Q9HGP0", "SPBC317.01", "Q09892", "SPAC24B11.06c" ] }, "reaction_10754565": { "compartment": "compartment_12045", "id": "reaction_10754565", "reactome": "R-SPO-8857686", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549167", "species_10754559" ], "products": [ "species_10754563" ], "modifiers": [], "additional_components": [ "SPBC543.08", "Q9HGM4", "SPBC543.08", "species_549167" ] }, "reaction_10732605": { "compartment": "compartment_5460", "id": "reaction_10732605", "reactome": "R-SPO-73920", "name": "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73911", "species_113526" ], "products": [ "species_73909", "species_29362", "species_113529" ], "modifiers": [ [ "species_10732592", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10744280": { "compartment": "compartment_7660", "id": "reaction_10744280", "reactome": "R-SPO-3371518", "name": "SIRT1 binds to HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738936", "species_10744242" ], "products": [ "species_10744244" ], "modifiers": [], "additional_components": [ "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O94640", "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06" ] }, "reaction_10747248": { "compartment": "compartment_7660", "id": "reaction_10747248", "reactome": "R-SPO-5682026", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747243", "species_29358" ], "products": [ "species_10737781", "species_113582", "species_10747245" ], "modifiers": [ [ "species_10747243", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "SPCC23B6.03c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744330": { "compartment": "compartment_70101", "id": "reaction_10744330", "reactome": "R-SPO-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744328", "species_10744326" ], "products": [ "species_10744167" ], "modifiers": [], "additional_components": [ "O59855", "SPCC1739.13", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q09912", "SPCC830.07c", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11" ] }, "reaction_10745619": { "compartment": "compartment_7660", "id": "reaction_10745619", "reactome": "R-SPO-5333051", "name": "RPA1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729504", "species_10744252" ], "products": [ "species_10745617" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q92373", "SPCC1753.01c", "Q02953", "SPAC2E12.02", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c" ] }, "reaction_10746067": { "compartment": "compartment_70101", "id": "reaction_10746067", "reactome": "R-SPO-5618107", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10744276" ], "products": [ "species_10746061" ], "modifiers": [], "additional_components": [ "O59855", "SPCC1739.13", "P41887", "SPAC926.04c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q9USI5", "SPCC645.14c", "O59855", "SPCC1739.13", "P41887", "SPAC926.04c", "species_29370", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q9USI5", "SPCC645.14c" ] }, "reaction_10747237": { "compartment": "compartment_7660", "id": "reaction_10747237", "reactome": "R-SPO-5682020", "name": "MRN complex binds shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3785706", "species_10733251" ], "products": [ "species_10747220" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744259": { "compartment": "compartment_7660", "id": "reaction_10744259", "reactome": "R-SPO-3371467", "name": "SIRT1 deacetylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_427523", "species_10744244" ], "products": [ "species_10738936", "species_427498", "species_427497", "species_10744256" ], "modifiers": [ [ "species_10744244", "catalyst" ] ], "additional_components": [ "O94640", "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "SPBC16D10.07c", "O59855", "SPCC1739.13", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O94640", "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06" ] }, "reaction_10744307": { "compartment": "compartment_70101", "id": "reaction_10744307", "reactome": "R-SPO-3371531", "name": "Constitutive phosphorylation by pERK1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10744185" ], "products": [ "species_29370", "species_10744298" ], "modifiers": [ [ "species_10744304", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10744172": { "compartment": "compartment_70101", "id": "reaction_10744172", "reactome": "R-SPO-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744167" ], "products": [ "species_10744169", "species_29372" ], "modifiers": [ [ "species_10744167", "catalyst" ], [ "species_10744165", "catalyst" ] ], "additional_components": [ "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "Q09912", "SPCC830.07c", "O74752", "SPBC1734.11" ] }, "reaction_10744208": { "compartment": "compartment_70101", "id": "reaction_10744208", "reactome": "R-SPO-3371435", "name": "Constitutive phosphorylation by GSK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10744185" ], "products": [ "species_29370", "species_10744193" ], "modifiers": [ [ "species_10744205", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q9URT9", "SPBC8D2.01", "Q10452", "SPAC1687.15" ] }, "reaction_10747235": { "compartment": "compartment_7660", "id": "reaction_10747235", "reactome": "R-SPO-5682018", "name": "MRN complex bound to shortened telomeres recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747220", "species_10747231" ], "products": [ "species_10747233" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "O74630", "SPCC23B6.03c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744278": { "compartment": "compartment_70101", "id": "reaction_10744278", "reactome": "R-SPO-3371503", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744264", "species_10744169", "species_10744270" ], "products": [ "species_10744165", "species_10744276" ], "modifiers": [], "additional_components": [ "SPCC645.14c", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "P41887", "SPAC926.04c", "Q09912", "SPCC830.07c", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "P41887", "SPAC926.04c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q9USI5", "SPCC645.14c" ] }, "reaction_10738160": { "compartment": "compartment_12045", "id": "reaction_10738160", "reactome": "R-SPO-381091", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738152", "species_113592" ], "products": [ "species_10738157", "species_29370" ], "modifiers": [ [ "species_10738152", "catalyst" ] ], "additional_components": [ "O94537", "SPAC167.01", "O94537", "SPAC167.01", "O94537", "SPAC167.01" ] }, "reaction_10738162": { "compartment": "compartment_12045", "id": "reaction_10738162", "reactome": "R-SPO-381109", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738150" ], "products": [ "species_10738152" ], "modifiers": [], "additional_components": [ "SPAC167.01", "O94537", "SPAC167.01" ] }, "reaction_10751159": { "compartment": "compartment_7660", "id": "reaction_10751159", "reactome": "R-SPO-6792712", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747233", "species_113560" ], "products": [ "species_10747243", "species_2485002" ], "modifiers": [ [ "species_10747233", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10752180": { "compartment": "compartment_70101", "id": "reaction_10752180", "reactome": "R-SPO-6799545", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6799540", "species_29356" ], "products": [ "species_429579", "species_6799543" ], "modifiers": [ [ "species_10752177", "catalyst" ] ], "additional_components": [ "Q9UT61", "SPAC513.05", "species_442320" ] }, "reaction_10757491": { "compartment": "compartment_70101", "id": "reaction_10757491", "reactome": "R-SPO-9638127", "name": "PGM1:Mg2+ isomerises G6P to G1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537" ], "products": [ "species_29548" ], "modifiers": [ [ "species_10757486", "catalyst" ] ], "additional_components": [ "O74374", "SPBC32F12.10", "species_29926" ] }, "reaction_10729677": { "compartment": "compartment_70101", "id": "reaction_10729677", "reactome": "R-SPO-70369", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29452" ], "products": [ "species_29410" ], "modifiers": [ [ "species_10729674", "catalyst" ] ], "additional_components": [ "Q9HDU3", "SPBPB2B2.12c", "species_113526" ] }, "reaction_10729722": { "compartment": "compartment_70101", "id": "reaction_10729722", "reactome": "R-SPO-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10729644", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10757179": { "compartment": "compartment_161320", "id": "reaction_10757179", "reactome": "R-SPO-9036727", "name": "GAA hydrolyzes lysosomal glycogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757148", "species_1605715" ], "products": [ "species_1605745", "species_10757158" ], "modifiers": [ [ "species_10757176", "catalyst" ] ], "additional_components": [ "O43062", "SPBC4C3.09", "Q09680", "SPBC4C3.09", "species_113527", "O43061", "SPBC4C3.08", "O43062", "SPBC4C3.09", "Q09680", "SPBC4C3.09", "species_113527", "O43061", "SPBC4C3.08", "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10740698": { "compartment": "compartment_70101", "id": "reaction_10740698", "reactome": "R-SPO-927789", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740694", "species_10740674" ], "products": [ "species_10740696" ], "modifiers": [], "additional_components": [ "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "P79015", "SPAC3H5.10", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "species_29420", "Q09127", "SPBC18E5.04", "P08094", "SPBP8B7.06", "P0CT76", "SPBP4H10.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "O74893", "SPCC576.09", "P0CT68", "SPAC3A12.10", "Q9P3T6", "SPAC328.10c", "Q9USR7", "SPBC577.02", "Q9UTG4", "SPAC1805.11c", "Q9P383", "SPBC13A2.01c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O42699", "SPCC1682.14", "P0CT83", "SPCC16C4.13c", "Q9P4W9", "SPAC959.07", "Q9US22", "SPAC1783.08c", "O74172", "SPBC3D6.15", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "Q9P546", "SPAPJ698.02c", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07", "SPAC16C9.06c", "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "P79015", "SPAC3H5.10", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "species_29420", "Q09127", "SPBC18E5.04", "P08094", "SPBP8B7.06", "P0CT76", "SPBP4H10.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "O74893", "SPCC576.09", "P0CT68", "SPAC3A12.10", "Q9P3T6", "SPAC328.10c", "Q9USR7", "SPBC577.02", "Q9UTG4", "SPAC1805.11c", "Q09820", "SPAC16C9.06c", "Q9P383", "SPBC13A2.01c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O42699", "SPCC1682.14", "P0CT83", "SPCC16C4.13c", "Q9P4W9", "SPAC959.07", "Q9US22", "SPAC1783.08c", "O74172", "SPBC3D6.15", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "Q9P546", "SPAPJ698.02c", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07" ] }, "reaction_10737896": { "compartment": "compartment_70101", "id": "reaction_10737896", "reactome": "R-SPO-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10737893", "catalyst" ] ], "additional_components": [ "SPAC1002.07c" ] }, "reaction_10730001": { "compartment": "compartment_70101", "id": "reaction_10730001", "reactome": "R-SPO-70634", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498", "species_113567" ], "products": [ "species_113585", "species_29968" ], "modifiers": [ [ "species_10729998", "catalyst" ] ], "additional_components": [ "SPAC4G9.20c" ] }, "reaction_10729981": { "compartment": "compartment_70101", "id": "reaction_10729981", "reactome": "R-SPO-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29448", "species_113592", "species_29356" ], "products": [ "species_29404", "species_29642", "species_111294", "species_76577" ], "modifiers": [ [ "species_10729978", "catalyst" ] ], "additional_components": [ "P78753", "SPBC119.10" ] }, "reaction_10756871": { "compartment": "compartment_5460", "id": "reaction_10756871", "reactome": "R-SPO-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013199", "species_9012592" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10737898": { "compartment": "compartment_70101", "id": "reaction_10737898", "reactome": "R-SPO-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_76194", "species_353555" ], "modifiers": [ [ "species_10737893", "catalyst" ] ], "additional_components": [ "SPAC1002.07c" ] }, "reaction_10757130": { "compartment": "compartment_70101", "id": "reaction_10757130", "reactome": "R-SPO-9034539", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10756881", "catalyst" ] ], "additional_components": [ "O59791", "SPCC320.14" ] }, "reaction_10756803": { "compartment": "compartment_5460", "id": "reaction_10756803", "reactome": "R-SPO-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10741569": { "compartment": "compartment_70101", "id": "reaction_10741569", "reactome": "R-SPO-1237129", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237176", "species_29356" ], "products": [ "species_70106", "species_1237155", "species_29372" ], "modifiers": [ [ "species_10741566", "catalyst" ] ], "additional_components": [ "species_29926", "Q9P6Q2", "SPAC644.08" ] }, "reaction_10729971": { "compartment": "compartment_5460", "id": "reaction_10729971", "reactome": "R-SPO-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113552", "species_113587" ], "modifiers": [ [ "species_10729968", "catalyst" ] ], "additional_components": [ "O94320", "SPBC725.01" ] }, "reaction_10740926": { "compartment": "compartment_70101", "id": "reaction_10740926", "reactome": "R-SPO-977324", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_936706" ], "products": [ "species_200736", "species_29372" ], "modifiers": [ [ "species_10740923", "catalyst" ] ], "additional_components": [ "O74382", "SPBC3H7.07c", "species_29926" ] }, "reaction_10742240": { "compartment": "compartment_70101", "id": "reaction_10742240", "reactome": "R-SPO-1614631", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369", "species_29356" ], "products": [ "species_1614532", "species_29382", "species_936714" ], "modifiers": [ [ "species_10742218", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10742221": { "compartment": "compartment_70101", "id": "reaction_10742221", "reactome": "R-SPO-1614567", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369" ], "products": [ "species_1614532", "species_1614594" ], "modifiers": [ [ "species_10742218", "catalyst" ], [ "species_174369", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10740937": { "compartment": "compartment_70101", "id": "reaction_10740937", "reactome": "R-SPO-977333", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_977329" ], "products": [ "species_936706", "species_29406" ], "modifiers": [ [ "species_10740934", "catalyst" ] ], "additional_components": [ "Q10349", "SPAC1F12.07" ] }, "reaction_10729901": { "compartment": "compartment_70101", "id": "reaction_10729901", "reactome": "R-SPO-70524", "name": "PXLP-K314-GPT transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_29398" ], "products": [ "species_29406", "species_29432" ], "modifiers": [ [ "species_10729896", "catalyst" ] ], "additional_components": [ "Q10334", "SPBC582.08" ] }, "reaction_10741559": { "compartment": "compartment_70101", "id": "reaction_10741559", "reactome": "R-SPO-1237119", "name": "Acireductone is oxidized to MOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237155", "species_29368" ], "products": [ "species_1237122", "species_29460" ], "modifiers": [ [ "species_10741556", "catalyst" ] ], "additional_components": [ "species_113531", "O94286", "SPBC887.01" ] }, "reaction_10741654": { "compartment": "compartment_70101", "id": "reaction_10741654", "reactome": "R-SPO-1299507", "name": "Methylthio-ribulose-P = Methylthio-ribose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237107" ], "products": [ "species_1237165" ], "modifiers": [ [ "species_10741546", "catalyst" ] ], "additional_components": [ "SPBC23E6.10c" ] }, "reaction_10729947": { "compartment": "compartment_70101", "id": "reaction_10729947", "reactome": "R-SPO-70573", "name": "argininosuccinate <=> fumarate + arginine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_34575" ], "products": [ "species_29586", "species_29468" ], "modifiers": [ [ "species_10729944", "catalyst" ] ], "additional_components": [ "P50514", "SPBC1539.03c" ] }, "reaction_10757135": { "compartment": "compartment_5460", "id": "reaction_10757135", "reactome": "R-SPO-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756666", "species_9012592" ], "products": [ "species_10757133", "species_113557" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01", "SPCC4B3.01", "SPCC4B3.01" ] }, "reaction_10740139": { "compartment": "compartment_5460", "id": "reaction_10740139", "reactome": "R-SPO-507749", "name": "PXLP-K341-GPT2 transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113557" ], "products": [ "species_113594", "species_379697" ], "modifiers": [ [ "species_10740136", "catalyst" ] ], "additional_components": [ "Q10334", "SPBC582.08" ] }, "reaction_10737914": { "compartment": "compartment_70101", "id": "reaction_10737914", "reactome": "R-SPO-351222", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284" ], "products": [ "species_353113", "species_113528" ], "modifiers": [ [ "species_10737911", "catalyst" ] ], "additional_components": [ "SPBP4H10.05c" ] }, "reaction_10742237": { "compartment": "compartment_70101", "id": "reaction_10742237", "reactome": "R-SPO-1614614", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_29356" ], "products": [ "species_1614532", "species_200736" ], "modifiers": [ [ "species_10742218", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10749651": { "compartment": "compartment_876", "id": "reaction_10749651", "reactome": "R-SPO-5693783", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693762" ], "products": [ "species_29404", "species_5693772" ], "modifiers": [ [ "species_10749648", "catalyst" ] ], "additional_components": [ "O43023", "SPBC354.09c" ] }, "reaction_10755607": { "compartment": "compartment_70101", "id": "reaction_10755607", "reactome": "R-SPO-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10755604", "catalyst" ] ], "additional_components": [ "SPBC1778.07" ] }, "reaction_10730041": { "compartment": "compartment_70101", "id": "reaction_10730041", "reactome": "R-SPO-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10730038", "catalyst" ] ], "additional_components": [ "SPAC144.04c" ] }, "reaction_10729917": { "compartment": "compartment_5460", "id": "reaction_10729917", "reactome": "R-SPO-70555", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113561", "species_29896", "species_113593" ], "products": [ "species_29676", "species_113548", "species_113581" ], "modifiers": [ [ "species_10729914", "catalyst" ], [ "species_30471", "catalyst" ] ], "additional_components": [ "SPAC22G7.06c" ] }, "reaction_10756873": { "compartment": "compartment_5460", "id": "reaction_10756873", "reactome": "R-SPO-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10756884": { "compartment": "compartment_70101", "id": "reaction_10756884", "reactome": "R-SPO-9014741", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_376186" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10756881", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "O59791", "SPCC320.14" ] }, "reaction_10729937": { "compartment": "compartment_70101", "id": "reaction_10729937", "reactome": "R-SPO-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29356" ], "products": [ "species_29498", "species_29514" ], "modifiers": [ [ "species_10729934", "catalyst" ] ], "additional_components": [ "species_113527", "Q10066", "SPAC3H1.07" ] }, "reaction_10729927": { "compartment": "compartment_5460", "id": "reaction_10729927", "reactome": "R-SPO-70560", "name": "carbamoyl phosphate + ornithine => citrulline + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29676", "species_113585" ], "products": [ "species_113548", "species_113567" ], "modifiers": [ [ "species_10729924", "catalyst" ] ], "additional_components": [ "P31317", "SPAC4G9.10" ] }, "reaction_10756887": { "compartment": "compartment_70101", "id": "reaction_10756887", "reactome": "R-SPO-9014766", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_376186" ], "modifiers": [ [ "species_10756881", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "O59791", "SPCC320.14" ] }, "reaction_10755833": { "compartment": "compartment_70101", "id": "reaction_10755833", "reactome": "R-SPO-8932980", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_8932979" ], "modifiers": [ [ "species_10755830", "catalyst" ] ], "additional_components": [ "Q9HDY3", "SPAPB1A10.07c" ] }, "reaction_10756669": { "compartment": "compartment_5460", "id": "reaction_10756669", "reactome": "R-SPO-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10741579": { "compartment": "compartment_70101", "id": "reaction_10741579", "reactome": "R-SPO-1237160", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353106", "species_29372" ], "products": [ "species_83951", "species_1237165" ], "modifiers": [ [ "species_10741576", "catalyst" ] ], "additional_components": [ "Q09816", "SPAC16C9.02c" ] }, "reaction_10737906": { "compartment": "compartment_70101", "id": "reaction_10737906", "reactome": "R-SPO-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_353106", "species_204635" ], "modifiers": [ [ "species_10737903", "catalyst" ] ], "additional_components": [ "SPBC12C2.07c" ] }, "reaction_10729958": { "compartment": "compartment_70101", "id": "reaction_10729958", "reactome": "R-SPO-70581", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76213", "species_29404" ], "products": [ "species_29448", "species_29406" ], "modifiers": [ [ "species_10729955", "catalyst" ] ], "additional_components": [ "O42652", "SPAC10F6.13c" ] }, "reaction_10742227": { "compartment": "compartment_70101", "id": "reaction_10742227", "reactome": "R-SPO-1614591", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707" ], "products": [ "species_1614532", "species_1614582" ], "modifiers": [ [ "species_10742218", "catalyst" ], [ "species_111707", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10729909": { "compartment": "compartment_5460", "id": "reaction_10729909", "reactome": "R-SPO-70542", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113559" ], "products": [ "species_29374", "species_30471" ], "modifiers": [ [ "species_10729906", "catalyst" ], [ "species_374064", "catalyst" ] ], "additional_components": [ "SPAC4G9.09c" ] }, "reaction_10739964": { "compartment": "compartment_5460", "id": "reaction_10739964", "reactome": "R-SPO-452036", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_374064" ], "products": [ "species_113585", "species_374061" ], "modifiers": [ [ "species_10739961", "catalyst" ] ], "additional_components": [ "species_113527", "Q10066", "SPAC3H1.07", "P37818", "SPBP26C9.02c" ] }, "reaction_10734644": { "compartment": "compartment_7660", "id": "reaction_10734644", "reactome": "R-SPO-156682", "name": "PLK1 phosphorylates NUDC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734638" ], "products": [ "species_29370", "species_10734642" ], "modifiers": [ [ "species_10734630", "catalyst" ] ], "additional_components": [ "SPBC19F8.02", "SPBC19F8.02", "SPAC23C11.16" ] }, "reaction_10734452": { "compartment": "compartment_7660", "id": "reaction_10734452", "reactome": "R-SPO-112396", "name": "Separation of elongating transcript from template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734448" ], "products": [ "species_10734450" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734466": { "compartment": "compartment_7660", "id": "reaction_10734466", "reactome": "R-SPO-113412", "name": "Pol II elongation complex moves on the template as transcript elongates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10734436" ], "products": [ "species_9757634", "species_10734448" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734438": { "compartment": "compartment_7660", "id": "reaction_10734438", "reactome": "R-SPO-112385", "name": "Addition of nucleotides leads to transcript elongation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10734434" ], "products": [ "species_10732494", "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O42668", "SPAC27D7.14c", "O74995", "SPCC1682.07", "A0ZWU1", "SPCC1223.10c", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "P36613", "SPBP16F5.02", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734460": { "compartment": "compartment_7660", "id": "reaction_10734460", "reactome": "R-SPO-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734363", "species_10734299" ], "products": [ "species_10734365" ], "modifiers": [], "additional_components": [ "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13936", "SPAC23C4.19", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10734370": { "compartment": "compartment_7660", "id": "reaction_10734370", "reactome": "R-SPO-112383", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732494", "species_10730702", "species_10734304" ], "products": [ "species_10734363", "species_10732494" ], "modifiers": [ [ "species_10734304", "catalyst" ] ], "additional_components": [ "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "SPAC19B12.05c", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "SPAC19B12.05c" ] }, "reaction_10742959": { "compartment": "compartment_70101", "id": "reaction_10742959", "reactome": "R-SPO-2161549", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_265283" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10737651": { "compartment": "compartment_70101", "id": "reaction_10737651", "reactome": "R-SPO-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10737648", "catalyst" ] ], "additional_components": [ "SPAC9E9.13" ] }, "reaction_10742962": { "compartment": "compartment_70101", "id": "reaction_10742962", "reactome": "R-SPO-2161614", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_879629" ], "products": [ "species_29366", "species_2142710" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10748696": { "compartment": "compartment_70101", "id": "reaction_10748696", "reactome": "R-SPO-5690043", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690044", "species_29356" ], "products": [ "species_76194", "species_5690064" ], "modifiers": [ [ "species_10748693", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "species_174602", "CHEBI:59554", "P87304", "SPBC31F10.02" ] }, "reaction_10755098": { "compartment": "compartment_12045", "id": "reaction_10755098", "reactome": "R-SPO-8869206", "name": "PAFAH2 hydrolyses PAF to lyso-PAF and acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8869214", "species_29356" ], "products": [ "species_8869207", "species_29416" ], "modifiers": [ [ "species_10755095", "catalyst" ] ], "additional_components": [ "SPBC106.11c" ] }, "reaction_10746338": { "compartment": "compartment_70101", "id": "reaction_10746338", "reactome": "R-SPO-5631885", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29408", "species_10744090" ], "products": [ "species_29356", "species_10746335" ], "modifiers": [ [ "species_10744090", "catalyst" ] ], "additional_components": [ "O74887", "SPCC576.03c", "O74887", "SPCC576.03c", "O74887", "SPCC576.03c" ] }, "reaction_10735170": { "compartment": "compartment_70101", "id": "reaction_10735170", "reactome": "R-SPO-165179", "name": "Formation of TSC1:TSC2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735151", "species_10735164" ], "products": [ "species_10735168" ], "modifiers": [], "additional_components": [ "SPAC630.13c", "SPAC22F3.13", "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c" ] }, "reaction_10757294": { "compartment": "compartment_7660", "id": "reaction_10757294", "reactome": "R-SPO-9613494", "name": "Unwinding of DNA for the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10733310" ], "products": [ "species_164121", "species_113541", "species_10733310" ], "modifiers": [ [ "species_10732494", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07" ] }, "reaction_10733352": { "compartment": "compartment_7660", "id": "reaction_10733352", "reactome": "R-SPO-75869", "name": "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733310" ], "products": [ "species_10733350", "species_10732624", "species_113541" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "SPAC16E8.16", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10734065": { "compartment": "compartment_7660", "id": "reaction_10734065", "reactome": "R-SPO-111264", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733549" ], "products": [ "species_113541", "species_10733586" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10753227": { "compartment": "compartment_7660", "id": "reaction_10753227", "reactome": "R-SPO-6810233", "name": "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10753215" ], "products": [ "species_113582", "species_10753224" ], "modifiers": [ [ "species_10753215", "catalyst" ] ], "additional_components": [ "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "O14098", "SPAC2F3.15", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "O59748", "SPBC530.13", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "O14098", "SPAC2F3.15", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O59748", "SPBC530.13", "O60076", "SPCC1494.02c", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "O14098", "SPAC2F3.15", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "O59748", "SPBC530.13" ] }, "reaction_10733584": { "compartment": "compartment_7660", "id": "reaction_10733584", "reactome": "R-SPO-77069", "name": "RNA Polymerase II CTD (phosphorylated) binds to CE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733582", "species_10733576" ], "products": [ "species_10733578" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "SPBC2F12.08c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733356": { "compartment": "compartment_7660", "id": "reaction_10733356", "reactome": "R-SPO-75873", "name": "Addition of Nucleotides 5 through 9 on the growing Transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733350" ], "products": [ "species_10733354", "species_10732699", "species_10732619", "species_10732711", "species_113541" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10757296": { "compartment": "compartment_7660", "id": "reaction_10757296", "reactome": "R-SPO-9613497", "name": "Unwinding DNA for the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10732713" ], "products": [ "species_10732713", "species_113541" ], "modifiers": [ [ "species_10732494", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07" ] }, "reaction_10734472": { "compartment": "compartment_7660", "id": "reaction_10734472", "reactome": "R-SPO-113430", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733586" ], "products": [ "species_10733586" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733580": { "compartment": "compartment_7660", "id": "reaction_10733580", "reactome": "R-SPO-77068", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733578" ], "products": [ "species_10733578" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733604": { "compartment": "compartment_7660", "id": "reaction_10733604", "reactome": "R-SPO-77073", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733578", "species_10733594", "species_10733600" ], "products": [ "species_10733602" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "SPCC330.10", "SPAC23C4.19", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733415": { "compartment": "compartment_7660", "id": "reaction_10733415", "reactome": "R-SPO-75949", "name": "RNA Polymerase II Promoter Opening: First Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10733340" ], "products": [ "species_113582", "species_113550", "species_10733332" ], "modifiers": [ [ "species_10732494", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07" ] }, "reaction_10733589": { "compartment": "compartment_7660", "id": "reaction_10733589", "reactome": "R-SPO-77071", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10733586" ], "products": [ "species_113582", "species_10733582" ], "modifiers": [ [ "species_10733586", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733551": { "compartment": "compartment_7660", "id": "reaction_10733551", "reactome": "R-SPO-76576", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733354", "species_9757634" ], "products": [ "species_113541", "species_10733549" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10752508": { "compartment": "compartment_7660", "id": "reaction_10752508", "reactome": "R-SPO-6802973", "name": "PLK3 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732945", "species_29358" ], "products": [ "species_113582", "species_10752503" ], "modifiers": [ [ "species_10752505", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC23C11.16" ] }, "reaction_10733313": { "compartment": "compartment_7660", "id": "reaction_10733313", "reactome": "R-SPO-75850", "name": "Addition of the third nucleotide on the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10732713" ], "products": [ "species_113541", "species_10733310" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10757952": { "compartment": "compartment_70101", "id": "reaction_10757952", "reactome": "R-SPO-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_29366", "species_469662" ], "modifiers": [ [ "species_10744798", "catalyst" ] ], "additional_components": [ "SPAC7D4.09c" ] }, "reaction_10736294": { "compartment": "compartment_17957", "id": "reaction_10736294", "reactome": "R-SPO-194023", "name": "HSD11B2,HSD11B1 dimer oxidise CORT to COR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_193977" ], "products": [ "species_70106", "species_29364", "species_194035" ], "modifiers": [ [ "species_10736291", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10740318": { "compartment": "compartment_70101", "id": "reaction_10740318", "reactome": "R-SPO-804969", "name": "HSD17B1 hydrogenates E1 to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193066" ], "products": [ "species_29366", "species_193132" ], "modifiers": [ [ "species_10740315", "catalyst" ] ], "additional_components": [ "O74628", "SPCC162.03" ] }, "reaction_10736285": { "compartment": "compartment_70101", "id": "reaction_10736285", "reactome": "R-SPO-193961", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196366" ], "products": [ "species_193092" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10750043": { "compartment": "compartment_5460", "id": "reaction_10750043", "reactome": "R-SPO-5696822", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696835", "species_113563" ], "products": [ "species_113600", "species_5696848", "species_113529" ], "modifiers": [ [ "species_10750040", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736362": { "compartment": "compartment_70101", "id": "reaction_10736362", "reactome": "R-SPO-196372", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193124", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196366" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10754586": { "compartment": "compartment_70101", "id": "reaction_10754586", "reactome": "R-SPO-8862137", "name": "HSD17B2 oxidises estradiol (E2) to estrone (E1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_176619" ], "products": [ "species_70106", "species_29364", "species_193066" ], "modifiers": [ [ "species_10754583", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10736243": { "compartment": "compartment_70101", "id": "reaction_10736243", "reactome": "R-SPO-193073", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_176626" ], "products": [ "species_70106", "species_73473", "species_193079" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10743335": { "compartment": "compartment_70101", "id": "reaction_10743335", "reactome": "R-SPO-2509831", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509848", "species_29356" ], "products": [ "species_70106", "species_111584", "species_111294" ], "modifiers": [ [ "species_10743329", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q9UU89", "SPCC830.10" ] }, "reaction_10743338": { "compartment": "compartment_70101", "id": "reaction_10743338", "reactome": "R-SPO-2509838", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509835", "species_29356" ], "products": [ "species_70106", "species_9731659", "species_111294" ], "modifiers": [ [ "species_10743329", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q9UU89", "SPCC830.10" ] }, "reaction_10732747": { "compartment": "compartment_70101", "id": "reaction_10732747", "reactome": "R-SPO-74255", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29356", "species_83956" ], "products": [ "species_30064", "species_31633" ], "modifiers": [ [ "species_10732744", "catalyst" ] ], "additional_components": [ "species_442320", "O14057", "SPCC1672.03c" ] }, "reaction_10743097": { "compartment": "compartment_70101", "id": "reaction_10743097", "reactome": "R-SPO-2393939", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1131972" ], "products": [ "species_73578", "species_76577" ], "modifiers": [ [ "species_10743094", "catalyst" ] ], "additional_components": [ "Q9P791", "SPBP35G2.12", "species_29926" ] }, "reaction_10743332": { "compartment": "compartment_70101", "id": "reaction_10743332", "reactome": "R-SPO-2509827", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2509836" ], "products": [ "species_70106", "species_29602", "species_111294" ], "modifiers": [ [ "species_10743329", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q9UU89", "SPCC830.10" ] }, "reaction_10756339": { "compartment": "compartment_70101", "id": "reaction_10756339", "reactome": "R-SPO-8953339", "name": "DNPH1 hydrolyses dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_109327" ], "products": [ "species_8953344", "species_83956" ], "modifiers": [ [ "species_10756336", "catalyst" ] ], "additional_components": [ "SPCC191.05c" ] }, "reaction_10733620": { "compartment": "compartment_7660", "id": "reaction_10733620", "reactome": "R-SPO-77081", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113571", "species_10733610" ], "products": [ "species_10733617", "species_111349" ], "modifiers": [ [ "species_10733610", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "species_29626", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733608": { "compartment": "compartment_7660", "id": "reaction_10733608", "reactome": "R-SPO-77077", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733602", "species_72084", "species_29428" ], "products": [ "species_10733606" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733634": { "compartment": "compartment_7660", "id": "reaction_10733634", "reactome": "R-SPO-77090", "name": "Methylation of GMP-cap by RNA Methyltransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733627", "species_77087" ], "products": [ "species_10732494", "species_10733631", "species_10730700", "species_10733600", "species_77502" ], "modifiers": [ [ "species_10733627", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "P40997", "SPBC2F12.08c", "O74880", "SPCC330.10", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "SPAC23C4.19", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733629": { "compartment": "compartment_7660", "id": "reaction_10733629", "reactome": "R-SPO-77085", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733622" ], "products": [ "species_10733627" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733636": { "compartment": "compartment_7660", "id": "reaction_10733636", "reactome": "R-SPO-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10730619", "species_10730614" ], "products": [ "species_10730621" ], "modifiers": [], "additional_components": [ "SPAC6G10.07", "SPBC13A2.01c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07" ] }, "reaction_10733625": { "compartment": "compartment_7660", "id": "reaction_10733625", "reactome": "R-SPO-77083", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733617" ], "products": [ "species_10733622" ], "modifiers": [ [ "species_10733617", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "species_29626", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "species_29626", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733613": { "compartment": "compartment_7660", "id": "reaction_10733613", "reactome": "R-SPO-77078", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733606" ], "products": [ "species_113550", "species_10733610" ], "modifiers": [ [ "species_10733606", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733638": { "compartment": "compartment_7660", "id": "reaction_10733638", "reactome": "R-SPO-77095", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10730621", "species_10730700" ], "products": [ "species_10730702" ], "modifiers": [], "additional_components": [ "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10742810": { "compartment": "compartment_70616", "id": "reaction_10742810", "reactome": "R-SPO-1955380", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742804", "species_10742802", "species_10742777" ], "products": [ "species_10742808" ], "modifiers": [], "additional_components": [ "SPCC24B10.05", "Q9P7K0", "SPCC24B10.05", "Q9USM7", "SPCC16A11.09c", "Q09188", "SPBC530.10c", "Q9UTE9", "SPAC222.03c", "P87130", "SPAC3A12.16c", "P87146", "SPBC25H2.04c", "SPBC25H2.04c", "Q9P7K0", "SPCC24B10.05", "Q9USM7", "SPCC16A11.09c", "Q09188", "SPBC530.10c", "Q9UTE9", "SPAC222.03c", "P87130", "SPAC3A12.16c", "P87146", "SPBC25H2.04c" ] }, "reaction_10756553": { "compartment": "compartment_5460", "id": "reaction_10756553", "reactome": "R-SPO-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756545" ], "products": [], "modifiers": [ [ "species_10756550", "catalyst" ] ], "additional_components": [ "O74831", "SPCC1183.03c", "P31317", "SPAC4G9.10", "Q9UTL6", "SPAC144.08", "Q09864", "SPAC12G12.04", "SPBC119.17" ] }, "reaction_10757288": { "compartment": "compartment_70101", "id": "reaction_10757288", "reactome": "R-SPO-9609921", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757284", "species_10757262" ], "products": [ "species_10757286" ], "modifiers": [], "additional_components": [ "O13644", "SPBC8D2.14c", "Q92356", "SPAC6G9.11", "O42646", "SPAC10F6.05c", "O43002", "SPBC2G2.03c", "O60119", "SPBC16G5.05c", "Q9USM6", "SPCC16A11.10c", "Q9USH7", "SPCC825.03c", "Q09827", "SPAC4G8.02c", "O13797", "SPAC1142.02c", "O13644", "SPBC8D2.14c", "Q92356", "SPAC6G9.11", "O42646", "SPAC10F6.05c", "O13797", "SPAC1142.02c", "O43002", "SPBC2G2.03c", "O60119", "SPBC16G5.05c", "Q9USM6", "SPCC16A11.10c", "Q9USH7", "SPCC825.03c", "Q09827", "SPAC4G8.02c" ] }, "reaction_10757305": { "compartment": "compartment_70101", "id": "reaction_10757305", "reactome": "R-SPO-9617595", "name": "SGTA binds mislocalized membrane protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757262", "species_10757280" ], "products": [ "species_10757303" ], "modifiers": [], "additional_components": [ "O13797", "SPAC1142.02c", "SPAC6G9.11", "Q92356", "SPAC6G9.11", "O13797", "SPAC1142.02c" ] } }, "motif_reaction_dictionary": { "reaction_10736615": { "compartment": "compartment_70101", "id": "reaction_10736615", "reactome": "R-SPO-198640", "name": "TORC2 (mTOR) phosphorylates AKT at S473", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10736578" ], "products": [ "species_29370", "species_10736485" ], "modifiers": [ [ "species_10736612", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "O14208", "SPAC6B12.03c", "Q09743", "SPBC12C2.02c", "Q9Y7K2", "SPBC216.07c", "O74547", "SPCC777.08c", "O74184", "SPBC21B10.05c", "Q9P7Y9", "SPAPYUG7.02c" ] }, "reaction_10736508": { "compartment": "compartment_70101", "id": "reaction_10736508", "reactome": "R-SPO-198270", "name": "PDPK1 phosphorylates AKT at T308", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10736487" ], "products": [ "species_10736505", "species_29370", "species_10733718" ], "modifiers": [ [ "species_10736487", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q12701", "SPCC576.15c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "species_179838", "Q12701", "SPCC576.15c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q12701", "SPCC576.15c" ] }, "reaction_10743083": { "compartment": "compartment_70101", "id": "reaction_10743083", "reactome": "R-SPO-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737088", "species_179838" ], "products": [ "species_10733718" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10738460": { "compartment": "compartment_70101", "id": "reaction_10738460", "reactome": "R-SPO-392530", "name": "p-S400-Cot phosphorylates NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10738454" ], "products": [ "species_29370", "species_10738457" ], "modifiers": [ [ "species_10738323", "catalyst" ] ], "additional_components": [ "SPAC1006.09", "SPAC1006.09", "O74304", "SPAC1006.09", "O14299", "SPAC9G1.02" ] }, "reaction_10743087": { "compartment": "compartment_70101", "id": "reaction_10743087", "reactome": "R-SPO-2317332", "name": "PIP3 recruits AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10738396" ], "products": [ "species_10736578" ], "modifiers": [], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c" ] }, "reaction_10738325": { "compartment": "compartment_70101", "id": "reaction_10738325", "reactome": "R-SPO-389756", "name": "AKT interacts and phosphorylates Cot", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10738315" ], "products": [ "species_29370", "species_10738323" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "O74304", "SPAC1006.09", "O14299", "SPAC9G1.02", "O74304", "SPAC1006.09", "O14299", "SPAC9G1.02", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10743085": { "compartment": "compartment_876", "id": "reaction_10743085", "reactome": "R-SPO-2317314", "name": "AKT binds PDPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733718", "species_10736485" ], "products": [ "species_10736487" ], "modifiers": [], "additional_components": [ "species_179838", "Q12701", "SPCC576.15c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q12701", "SPCC576.15c" ] }, "reaction_10730559": { "compartment": "compartment_70101", "id": "reaction_10730559", "reactome": "R-SPO-71732", "name": "PPA1 hydrolyzes pyrophosphate to orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111294", "species_29356" ], "products": [ "species_29372" ], "modifiers": [ [ "species_10730556", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "P87118", "SPAC3A12.02", "P19117", "SPAC23C11.05" ] }, "reaction_10739587": { "compartment": "compartment_12045", "id": "reaction_10739587", "reactome": "R-SPO-446214", "name": "Synthesis of dolichyl-phosphate-glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29410", "species_449299" ], "products": [ "species_110096", "species_532214" ], "modifiers": [ [ "species_10739584", "catalyst" ] ], "additional_components": [ "SPBC56F2.10c" ] }, "reaction_10750117": { "compartment": "compartment_7660", "id": "reaction_10750117", "reactome": "R-SPO-6781818", "name": "RNA Pol II initiates transcription from damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5688114", "species_10732494", "species_10730706" ], "products": [ "species_10750115" ], "modifiers": [], "additional_components": [ "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q02061", "SPAC23G3.01", "P36594", "SPBC28F2.12", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O13877", "SPAC1B3.12c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O14459", "SPACUNK4.06c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10750180": { "compartment": "compartment_7660", "id": "reaction_10750180", "reactome": "R-SPO-6781833", "name": "ERCC8 (CSA) binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750176", "species_10750129" ], "products": [ "species_10750167", "species_10750178" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9UT51", "SPAC222.16c", "O14122", "SPAC3A11.08", "O94308", "SPBC215.03c", "Q9UUJ7", "SPAC1952.12c", "O13895", "SPAC22A12.03c", "O94454", "SPAC1687.13c", "Q9USR0", "SPBC577.09", "Q9HFR0", "SPAPB17E12.04c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "Q9UT51", "SPAC222.16c", "O94308", "SPBC215.03c", "Q9UUJ7", "SPAC1952.12c", "O13895", "SPAC22A12.03c", "O94454", "SPAC1687.13c", "Q9HFR0", "SPAPB17E12.04c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10750201": { "compartment": "compartment_7660", "id": "reaction_10750201", "reactome": "R-SPO-6781867", "name": "ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729044", "species_10750178" ], "products": [ "species_10750198" ], "modifiers": [ [ "species_10750178", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10750122": { "compartment": "compartment_7660", "id": "reaction_10750122", "reactome": "R-SPO-6781824", "name": "Active RNA Pol II complex transcribes lesion-containing DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6781829", "species_10750115" ], "products": [ "species_10750119", "species_113541" ], "modifiers": [ [ "species_10750115", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10750235": { "compartment": "compartment_7660", "id": "reaction_10750235", "reactome": "R-SPO-6782069", "name": "UVSSA:USP7 deubiquitinates ERCC6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10750226" ], "products": [ "species_10729044", "species_10750232" ], "modifiers": [ [ "species_10750226", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750182": { "compartment": "compartment_7660", "id": "reaction_10750182", "reactome": "R-SPO-6781840", "name": "ERCC6 binds stalled RNA Pol II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750119", "species_10750127" ], "products": [ "species_10750129" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "SPCP25A2.02c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10739167": { "compartment": "compartment_70101", "id": "reaction_10739167", "reactome": "R-SPO-429978", "name": "Lsm1-7 Complex binds deadenylated mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739153", "species_429974" ], "products": [ "species_10739155" ], "modifiers": [], "additional_components": [ "O74499", "SPCC285.12", "O94408", "SPCC1620.01c", "Q9Y7M4", "SPBC9B6.05c", "O42978", "SPBC20F10.09", "Q9UUI1", "SPAC2F3.17c", "O42958", "SPBC19G7.10c", "P87173", "SPBC3D6.08c", "O14352", "SPBC30D10.06", "O74499", "SPCC285.12", "O94408", "SPCC1620.01c", "Q9Y7M4", "SPBC9B6.05c", "O42978", "SPBC20F10.09", "Q9UUI1", "SPAC2F3.17c", "O42958", "SPBC19G7.10c", "P87173", "SPBC3D6.08c", "O14352", "SPBC30D10.06" ] }, "reaction_10739245": { "compartment": "compartment_70101", "id": "reaction_10739245", "reactome": "R-SPO-430028", "name": "Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429974", "species_29356" ], "products": [ "species_109395", "species_109402", "species_429926", "species_76577", "species_113578" ], "modifiers": [ [ "species_10739242", "catalyst" ] ], "additional_components": [ "O42872", "SPAC3G9.10c", "O59821", "SPCC1840.11", "O94474", "SPCC1919.05", "O74774", "SPBC25B2.01", "O13903", "SPAC22A12.12c", "Q09150", "SPBC32F12.02", "O74918", "SPCC757.08", "O60124", "SPBC16G5.10", "Q9P7R3", "SPBC211.08c", "O59801", "SPCC550.03c", "Q09704", "SPAC2F7.14c", "O42894", "SPBC115.01c", "Q10205", "SPBC17D1.03c", "P37202", "SPBC26H8.10" ] }, "reaction_10739165": { "compartment": "compartment_70101", "id": "reaction_10739165", "reactome": "R-SPO-429961", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429926", "species_29356" ], "products": [ "species_429925", "species_430042" ], "modifiers": [ [ "species_10739162", "catalyst" ] ], "additional_components": [ "SPBP4H10.20" ] }, "reaction_10733646": { "compartment": "compartment_7660", "id": "reaction_10733646", "reactome": "R-SPO-77589", "name": "Recognition of AAUAAA sequence by CPSF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733642", "species_10731317" ], "products": [ "species_10733644" ], "modifiers": [], "additional_components": [ "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c" ] }, "reaction_10757633": { "compartment": "compartment_17938", "id": "reaction_10757633", "reactome": "R-SPO-9646468", "name": "mTORC1 binds RHEB:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757563", "species_10735183" ], "products": [ "species_10757565" ], "modifiers": [], "additional_components": [ "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "species_29438", "O94363", "SPBC428.16c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757544": { "compartment": "compartment_17938", "id": "reaction_10757544", "reactome": "R-SPO-9639286", "name": "RRAGC,D exchanges GTP for GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757537", "species_29420" ], "products": [ "species_29438", "species_10757541" ], "modifiers": [ [ "species_10757537", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757608": { "compartment": "compartment_17938", "id": "reaction_10757608", "reactome": "R-SPO-9645608", "name": "v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757552", "species_10757561" ], "products": [ "species_10757563" ], "modifiers": [], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "Q9Y7K2", "SPBC216.07c", "P87141", "SPAC57A7.11", "O74184", "SPBC21B10.05c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757570": { "compartment": "compartment_17938", "id": "reaction_10757570", "reactome": "R-SPO-9640195", "name": "RRAGA,B hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757565" ], "products": [ "species_10757567", "species_29372" ], "modifiers": [ [ "species_10757565", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "Q9Y7K2", "SPBC216.07c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P87141", "SPAC57A7.11", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "O74184", "SPBC21B10.05c", "Q9HDW6", "SPAPB2B4.05", "O94363", "SPBC428.16c", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757557": { "compartment": "compartment_17938", "id": "reaction_10757557", "reactome": "R-SPO-9640167", "name": "RRAGA,B exchanges GDP for GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757550" ], "products": [ "species_10757554", "species_29420" ], "modifiers": [ [ "species_10757550", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "species_29468", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "species_29468", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "species_29468", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10757606": { "compartment": "compartment_17938", "id": "reaction_10757606", "reactome": "R-SPO-9645598", "name": "RRAGC,D hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757537" ], "products": [ "species_29372", "species_10757541" ], "modifiers": [ [ "species_10757537", "catalyst" ] ], "additional_components": [ "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O14265", "SPAC7D4.10", "O74544", "SPCC777.05", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c", "O43046", "SPBC3B9.18c", "O14046", "SPAC2C4.13", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "species_29438", "Q9HDW6", "SPAPB2B4.05", "species_29420", "P50515", "SPAC1B3.14", "O74544", "SPCC777.05", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O74824", "SPBC337.13c", "O59823", "SPCC965.03", "O13742", "SPAC16E8.07c", "Q69Z14", "SPBC1685.16", "Q9Y7J2", "SPBC1778.05c" ] }, "reaction_10733230": { "compartment": "compartment_70101", "id": "reaction_10733230", "reactome": "R-SPO-75125", "name": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500006", "species_29370" ], "products": [ "species_113592", "species_500009" ], "modifiers": [ [ "species_10732253", "catalyst" ] ], "additional_components": [ "species_110096", "species_110094", "CHEBI:58593", "species_109395", "species_109378", "species_418075", "SPCC1795.05c" ] }, "reaction_10740122": { "compartment": "compartment_5460", "id": "reaction_10740122", "reactome": "R-SPO-482804", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME4)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_482803", "species_113593" ], "products": [ "species_482807", "species_113581" ], "modifiers": [ [ "species_10740119", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "P49740", "SPAC806.07" ] }, "reaction_10732360": { "compartment": "compartment_70101", "id": "reaction_10732360", "reactome": "R-SPO-73647", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10732357", "catalyst" ] ], "additional_components": [ "O42644", "SPAC10F6.03c" ] }, "reaction_10750485": { "compartment": "compartment_7660", "id": "reaction_10750485", "reactome": "R-SPO-6788810", "name": "AK6 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788813", "species_29358" ], "products": [ "species_113582", "species_6788807" ], "modifiers": [ [ "species_10750482", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "SPCC830.11c" ] }, "reaction_10734110": { "compartment": "compartment_70101", "id": "reaction_10734110", "reactome": "R-SPO-111751", "name": "RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10732350" ], "products": [ "species_10732348", "species_8866399", "species_29356" ], "modifiers": [ [ "species_10734107", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "P36603", "SPBC25D12.04", "P36602", "SPAC1F7.05", "CHEBI:29034" ] }, "reaction_10734119": { "compartment": "compartment_70101", "id": "reaction_10734119", "reactome": "R-SPO-111804", "name": "RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8866401", "species_10732350" ], "products": [ "species_10732348", "species_8866399", "species_29356" ], "modifiers": [ [ "species_10734116", "catalyst" ], [ "species_113592", "catalyst" ], [ "species_110644", "inhibitor" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "P36602", "SPAC1F7.05", "P36603", "SPBC25D12.04", "CHEBI:29034" ] }, "reaction_10740066": { "compartment": "compartment_70101", "id": "reaction_10740066", "reactome": "R-SPO-482621", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_482625" ], "products": [ "species_482627", "species_113592" ], "modifiers": [ [ "species_10740061", "catalyst" ] ], "additional_components": [ "species_29494", "species_500739", "species_29892", "species_110644", "species_30185", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:60471", "CHEBI:58369", "CHEBI:58595", "CHEBI:57667", "species_110096", "species_110094", "CHEBI:58593", "P49740", "SPAC806.07" ] }, "reaction_10733852": { "compartment": "compartment_70101", "id": "reaction_10733852", "reactome": "R-SPO-110145", "name": "AMP + ATP <=> ADP + ADP [AK2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_76577" ], "products": [ "species_29370" ], "modifiers": [ [ "species_10733847", "catalyst" ] ], "additional_components": [ "SPAC4G9.03" ] }, "reaction_10732370": { "compartment": "compartment_7660", "id": "reaction_10732370", "reactome": "R-SPO-73666", "name": "dUTP + H2O => dUMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_500739" ], "products": [ "species_113541", "species_500742", "species_9668967" ], "modifiers": [ [ "species_10732367", "catalyst" ] ], "additional_components": [ "Q9P6Q5", "SPAC644.05c" ] }, "reaction_10732510": { "compartment": "compartment_70101", "id": "reaction_10732510", "reactome": "R-SPO-73788", "name": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500071", "species_113592" ], "products": [ "species_500077", "species_29370" ], "modifiers": [ [ "species_10732507", "catalyst" ] ], "additional_components": [ "species_109327", "species_29626", "species_29420", "CHEBI:58595", "SPBC1198.05" ] }, "reaction_10752646": { "compartment": "compartment_70101", "id": "reaction_10752646", "reactome": "R-SPO-6806877", "name": "NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8866401" ], "products": [ "species_29370", "species_6806881" ], "modifiers": [ [ "species_10752643", "catalyst" ] ], "additional_components": [ "P49740", "SPAC806.07" ] }, "reaction_10732322": { "compartment": "compartment_70101", "id": "reaction_10732322", "reactome": "R-SPO-73596", "name": "dCMP + H2O => dUMP + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_109378", "species_29356" ], "products": [ "species_109382", "species_31633" ], "modifiers": [ [ "species_10732319", "catalyst" ] ], "additional_components": [ "O43012", "SPBC2G2.13c" ] }, "reaction_10732332": { "compartment": "compartment_70101", "id": "reaction_10732332", "reactome": "R-SPO-73605", "name": "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109382", "species_111355" ], "products": [ "species_109366", "species_73604" ], "modifiers": [ [ "species_10732329", "catalyst" ] ], "additional_components": [ "Q9UTI7", "SPAC15E1.04", "species_29926" ] }, "reaction_10740131": { "compartment": "compartment_70101", "id": "reaction_10740131", "reactome": "R-SPO-504054", "name": "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29494", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_110614", "species_29372" ], "modifiers": [ [ "species_10740128", "catalyst" ] ], "additional_components": [ "O42644", "SPAC10F6.03c" ] }, "reaction_10733843": { "compartment": "compartment_70101", "id": "reaction_10733843", "reactome": "R-SPO-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_6788782" ], "products": [ "species_113592", "species_6788778" ], "modifiers": [ [ "species_10733838", "catalyst" ] ], "additional_components": [ "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "species_109395", "species_76577", "species_109378", "species_109386", "SPAC4G9.03" ] }, "reaction_10733845": { "compartment": "compartment_70101", "id": "reaction_10733845", "reactome": "R-SPO-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_6788778" ], "products": [ "species_29370", "species_6788782" ], "modifiers": [ [ "species_10733838", "catalyst" ] ], "additional_components": [ "species_109395", "species_76577", "species_109378", "species_109386", "species_29370", "species_110094", "CHEBI:57667", "CHEBI:58593", "SPAC4G9.03" ] }, "reaction_10730480": { "compartment": "compartment_70101", "id": "reaction_10730480", "reactome": "R-SPO-71682", "name": "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_111745" ], "products": [ "species_29366", "species_29450" ], "modifiers": [ [ "species_10730477", "catalyst" ] ], "additional_components": [ "P78965", "SPBC17A3.07", "species_113596" ] }, "reaction_10739090": { "compartment": "compartment_70101", "id": "reaction_10739090", "reactome": "R-SPO-428941", "name": "P2Y purinoceptor 1 activates MAP kinase p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739086", "species_113592" ], "products": [ "species_29370", "species_10739088" ], "modifiers": [ [ "species_10734141", "catalyst" ] ], "additional_components": [ "SPAC24B11.06c", "SPAC24B11.06c", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10739107": { "compartment": "compartment_70101", "id": "reaction_10739107", "reactome": "R-SPO-428961", "name": "Phosphorylation of cPLA2 by MAPK p38 alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10739104" ], "products": [ "species_29370", "species_10734190" ], "modifiers": [ [ "species_10739088", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "SPAC24B11.06c" ] }, "reaction_10732235": { "compartment": "compartment_70101", "id": "reaction_10732235", "reactome": "R-SPO-72672", "name": "The 60S subunit joins the translation initiation complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732216", "species_10731817", "species_10732225" ], "products": [ "species_10732227" ], "modifiers": [], "additional_components": [ "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "P0C016", "SPAC6G10.11c", "O42706", "SPAC959.08", "P0C8R3", "SPAC589.10c", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O14388", "SPBC685.07c", "Q09668", "SPAC11E3.15", "P52822", "SPAC3H5.12c", "P36584", "SPAPB8E5.06c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P05733", "SPCC1223.05c", "Q9P784", "SPBC1711.06", "O74864", "SPCC18.14c", "O60143", "SPBC18H10.12c", "P0CT77", "SPAC26A3.07c", "P0CT61", 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computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_10731778", "species_10734741" ], "products": [ "species_10731755", "species_10731810" ], "modifiers": [], "additional_components": [ "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "O74743", "SPBC1709.18", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10734671": { "compartment": "compartment_70101", "id": "reaction_10734671", "reactome": "R-SPO-156808", "name": "Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_10734667", "species_10734655", "species_10731778" ], "products": [ "species_10731755", "species_10734669" ], "modifiers": [], "additional_components": [ "SPBC25H2.07", "Q9P6M8", "SPAC1610.03c", "P31209", "SPAC57A7.04c", "O74743", "SPBC1709.18", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "SPBC25H2.07", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10732241": { "compartment": "compartment_70101", "id": "reaction_10732241", "reactome": "R-SPO-72676", "name": "eIF3 and eIF1A bind to the 40S subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_10731750", "species_10731692" ], "products": [ "species_10732239" ], "modifiers": [], "additional_components": [ "SPBC25H2.07", "Q09722", "SPAC1751.03", "O94513", "SPBC646.09c", "Q10425", "SPAC25G10.08", "P79083", "SPAC4D7.05", "P87128", "SPAC3A12.13c", "O43060", "SPBC4C3.07", "Q9UT48", "SPAC821.05", "P78795", "SPBC18H10.03", "O94236", "SPAC637.07", "O74760", "SPBC17D11.05", "O14164", "SPAC4A8.16c", "O59675", "SPBC29A3.12", "Q9P7B2", "SPAC521.05", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P0CT74", "SPAC144.11", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P87158", "SPBC19F8.08", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0CT76", "SPBP4H10.13", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT80", "SPCC285.15c", "P0CT64", "SPBC18H10.14", "Q9UTG4", "SPAC1805.11c", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "P0CT58", "SPAC22A12.04c", "O13614", "SPBP22H7.08", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q9UTQ6", "SPAC1071.07c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "Q9P4W9", "SPAC959.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "O74172", "SPBC3D6.15", "P0CT66", "SPBC16D10.11c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10731821": { "compartment": "compartment_70101", "id": "reaction_10731821", "reactome": "R-SPO-72621", "name": "Ribosomal scanning ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10731810" ], "products": [ "species_29370", "species_10731810", "species_29372" ], "modifiers": [ [ "species_72617", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10732237": { "compartment": "compartment_70101", "id": "reaction_10732237", "reactome": "R-SPO-72673", "name": "Release of 40S and 60S subunits from the 80S ribosome ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. 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computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731774", "species_72393" ], "products": [ "species_10731776" ], "modifiers": [ [ "species_29438", "catalyst" ] ], "additional_components": [ "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c" ] }, "reaction_10731823": { "compartment": "compartment_70101", "id": "reaction_10731823", "reactome": "R-SPO-72631", "name": "Formation of the cap-binding eIF4F complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731789", "species_10731794", "species_10731799" ], "products": [ "species_10731801" ], "modifiers": [], "additional_components": [ "P47943", "SPAC1006.07", "SPBC1709.18", "SPAC17C9.03", "O74743", "SPBC1709.18", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07" ] }, "reaction_10731829": { "compartment": "compartment_70101", "id": "reaction_10731829", "reactome": "R-SPO-72663", "name": "De novo formation of eIF2:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10731772" ], "products": [ "species_10731774" ], "modifiers": [], "additional_components": [ "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c" ] }, "reaction_10732248": { "compartment": "compartment_70101", "id": "reaction_10732248", "reactome": "R-SPO-72722", "name": "eIF2 activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10731860" ], "products": [ "species_10731858", "species_10731774", "species_29420" ], "modifiers": [ [ "species_10731858", "catalyst" ] ], "additional_components": [ "species_29420", "P56286", "SPAC3G9.09c", "P56288", "SPAC4D7.09", "Q09130", "SPBC17G9.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "P56329", "SPAC32A11.04c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06", "P56288", "SPAC4D7.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c", "P56288", "SPAC4D7.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06" ] }, "reaction_10731862": { "compartment": "compartment_70101", "id": "reaction_10731862", "reactome": "R-SPO-72670", "name": "Formation of eIF2:GDP:eIF2B intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731819", "species_10731858" ], "products": [ "species_10731860" ], "modifiers": [], "additional_components": [ "species_29420", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c", "P56288", "SPAC4D7.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06", "species_29420", "P56286", "SPAC3G9.09c", "P56288", "SPAC4D7.09", "Q09130", "SPBC17G9.09", "Q9UT76", "SPAC343.14c", "P56287", "SPAC8C9.15c", "P56329", "SPAC32A11.04c", "Q9USP0", "SPCC11E10.07c", "Q09924", "SPAC21E11.06" ] }, "reaction_10732245": { "compartment": "compartment_70101", "id": "reaction_10732245", "reactome": "R-SPO-72697", "name": "Start codon recognition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731755", "species_72617", "species_10731810", "species_10731815", "species_10731772" ], "products": [ "species_10731755", "species_72617", "species_10731810", "species_10731815", "species_10731772" ], "modifiers": [ [ "species_72617", "catalyst" ] ], "additional_components": [ "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "SPAC2F7.05c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c", "SPBC25H2.07", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "SPAC2F7.05c", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "P56329", "SPAC32A11.04c" ] }, "reaction_10732243": { "compartment": "compartment_70101", "id": "reaction_10732243", "reactome": "R-SPO-72691", "name": "Formation of the 43S pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732239", "species_10731776" ], "products": [ "species_10731778" ], "modifiers": [], "additional_components": [ "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "P56286", "SPAC3G9.09c", "Q09130", "SPBC17G9.09", "species_29438", "P56329", "SPAC32A11.04c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10738284": { "compartment": "compartment_70101", "id": "reaction_10738284", "reactome": "R-SPO-389540", "name": "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_389545" ], "products": [ "species_70106", "species_29364", "species_113528", "species_29406" ], "modifiers": [ [ "species_10738281", "catalyst" ] ], "additional_components": [ "O14254", "SPAC6G10.08" ] }, "reaction_10734757": { "compartment": "compartment_13231", "id": "reaction_10734757", "reactome": "R-SPO-158481", "name": "Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734069" ], "products": [ "species_10734755" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10734749": { "compartment": "compartment_13231", "id": "reaction_10734749", "reactome": "R-SPO-158441", "name": "Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733677" ], "products": [ "species_10734747" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10733679": { "compartment": "compartment_7660", "id": "reaction_10733679", "reactome": "R-SPO-77594", "name": "Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733165", "species_10733675", "species_10730903" ], "products": [ "species_10730621", "species_10733677", "species_10731317" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1921.03c", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "SPCC126.11c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10733226": { "compartment": "compartment_13231", "id": "reaction_10733226", "reactome": "R-SPO-75097", "name": "Transport of the export-competent mRNP complex through the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733177" ], "products": [ "species_10733219" ], "modifiers": [ [ "species_10733155", "catalyst" ], [ "species_10733224", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "O94403", "SPCC126.11c", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "Q10267", "SPAC13G7.03", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9P383", "SPBC13A2.01c", "Q9URX8", "SPAC890.06", "Q10055", "SPAC1F5.10", "Q10168", "SPAC26A3.15c", "Q1MTR2", "SPBC13G1.14c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "O14253", "SPAC6G10.07", "Q09793", "SPAC22G7.09c", "P0CAN8", "SPAPB1A10.03", "O43044", "SPBC3B9.16c", "Q9Y8G3", "SPBC1921.03c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "O94403", "SPCC126.11c", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "Q10267", "SPAC13G7.03", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9P383", "SPBC13A2.01c", "Q9URX8", "SPAC890.06", "Q10055", "SPAC1F5.10", "Q10168", "SPAC26A3.15c", "Q1MTR2", "SPBC13G1.14c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "O14253", "SPAC6G10.07", "P0CAN8", "SPAPB1A10.03", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c", "SPBC31E1.05" ] }, "reaction_10734071": { "compartment": "compartment_7660", "id": "reaction_10734071", "reactome": "R-SPO-111439", "name": "Docking of Mature Histone mRNA complex:TAP at the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733165", "species_10730903", "species_10734067" ], "products": [ "species_10730621", "species_10734069" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1921.03c", "SPCC126.11c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10734761": { "compartment": "compartment_70101", "id": "reaction_10734761", "reactome": "R-SPO-158484", "name": "Release of the SLBP independent Histone mRNA from the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731794", "species_10734755" ], "products": [ "species_10734759", "species_10733187", "species_10733203" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1709.18", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "O74743", "SPBC1709.18", "SPBC1921.03c", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10734766": { "compartment": "compartment_7660", "id": "reaction_10734766", "reactome": "R-SPO-159101", "name": "NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733169", "species_10731417" ], "products": [ "species_113550", "species_10733175", "species_10734763" ], "modifiers": [ [ "species_10731417", "catalyst" ] ], "additional_components": [ "Q9Y8G3", "SPBC1921.03c", "P0CAN8", "SPAPB1A10.03", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "Q9P383", "SPBC13A2.01c", "C6Y4C0", "SPAC222.18", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "Q10267", "SPAC13G7.03", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q9Y8G3", "SPBC1921.03c", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "Q9USY2", "SPBC1861.04c", "Q10055", "SPAC1F5.10", "Q9Y7Y2", "SPBC365.05c", "Q1MTR2", "SPBC13G1.14c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "P0CAN8", "SPAPB1A10.03", "Q10267", "SPAC13G7.03", "species_29370", "O13792", "SPAC17G6.14c", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "Q9P383", "SPBC13A2.01c", "C6Y4C0", "SPAC222.18", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "Q10267", "SPAC13G7.03" ] }, "reaction_10734753": { "compartment": "compartment_70101", "id": "reaction_10734753", "reactome": "R-SPO-158447", "name": "Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731794", "species_10734747" ], "products": [ "species_10734751", "species_10733187", "species_10733203" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1709.18", "Q9Y8G3", "SPBC1921.03c", "Q9URV0", "SPCC126.11c", "O74743", "SPBC1709.18", "SPBC1921.03c", "SPCC126.11c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10746231": { "compartment": "compartment_7660", "id": "reaction_10746231", "reactome": "R-SPO-5625784", "name": "PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10746219" ], "products": [ "species_113582", "species_10746228" ], "modifiers": [ [ "species_10746219", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c" ] }, "reaction_10746240": { "compartment": "compartment_7660", "id": "reaction_10746240", "reactome": "R-SPO-5625796", "name": "Demethylase KDM4C binds KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746236", "species_10746228" ], "products": [ "species_10746238" ], "modifiers": [], "additional_components": [ "SPBC83.07", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "O94691", "SPBC83.07", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c" ] }, "reaction_10746249": { "compartment": "compartment_7660", "id": "reaction_10746249", "reactome": "R-SPO-5625797", "name": "KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10746238", "species_113685" ], "products": [ "species_10746236", "species_159942", "species_159939", "species_29478", "species_10746246" ], "modifiers": [ [ "species_10746238", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "O94691", "SPBC83.07", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "SPBC83.07", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P36583", "SPBC12D12.04c", "P04913", "SPCC622.09", "species_469662", "O94691", "SPBC83.07", "species_193079", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_193057", "CHEBI:29117", "P36582", "SPAC17G8.14c" ] }, "reaction_10740388": { "compartment": "compartment_17957", "id": "reaction_10740388", "reactome": "R-SPO-901047", "name": "Binding of ERp57", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740236", "species_10740384" ], "products": [ "species_10740386" ], "modifiers": [], "additional_components": [ "SPAC1F5.02", "Q9P7D0", "SPBP4H10.19c", "P36581", "SPAC3C7.11c", "CHEBI:59080", "Q9P7D0", "SPBP4H10.19c", "P36581", "SPAC3C7.11c", "Q10057", "SPAC1F5.02", "CHEBI:59080" ] }, "reaction_10741489": { "compartment": "compartment_70101", "id": "reaction_10741489", "reactome": "R-SPO-1022127", "name": "Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741485" ], "products": [ "species_10741487" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "CHEBI:59092", "CHEBI:60627", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "CHEBI:59087", "CHEBI:60629", "CHEBI:60628", "P0CH06", "SPAC11G7.04" ] }, "reaction_10750397": { "compartment": "compartment_1660541", "id": "reaction_10750397", "reactome": "R-SPO-6784738", "name": "Degradation of PCSK9:LDLR:Clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750393" ], "products": [ "species_10750391" ], "modifiers": [], "additional_components": [ "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P40903", "SPAC4A8.04", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10750395": { "compartment": "compartment_1660541", "id": "reaction_10750395", "reactome": "R-SPO-6784729", "name": "PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750361" ], "products": [ "species_10750393" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "P40903", "SPAC4A8.04", "Q9C0W7", "SPBC691.03c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P40903", "SPAC4A8.04" ] }, "reaction_10754372": { "compartment": "compartment_876", "id": "reaction_10754372", "reactome": "R-SPO-8855130", "name": "VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754362" ], "products": [ "species_10754370" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P40903", "SPAC4A8.04", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "P40903", "SPAC4A8.04", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10753477": { "compartment": "compartment_70101", "id": "reaction_10753477", "reactome": "R-SPO-6813720", "name": "NCEH1 hydrolyzes cholesterol esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163579", "species_29356" ], "products": [ "species_216762", "species_8876730" ], "modifiers": [ [ "species_10753474", "catalyst" ] ], "additional_components": [ "Q9US38", "SPAPB1A11.02", "Q9HDX3", "SPAPB1A11.02" ] }, "reaction_10735593": { "compartment": "compartment_70101", "id": "reaction_10735593", "reactome": "R-SPO-174401", "name": "AHCY:NAD+ tetramer hydrolyses AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71285", "species_29356" ], "products": [ "species_174369", "species_83909" ], "modifiers": [ [ "species_10735590", "catalyst" ] ], "additional_components": [ "O13639", "SPBC8D2.18c", "species_113526" ] }, "reaction_10735568": { "compartment": "compartment_70101", "id": "reaction_10735568", "reactome": "R-SPO-174391", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_174390", "species_29356" ], "products": [ "species_111294", "species_71284", "species_29372" ], "modifiers": [ [ "species_10735565", "catalyst" ] ], "additional_components": [ "O60198", "SPBC14F5.05c", "species_74126", "species_29926" ] }, "reaction_10752211": { "compartment": "compartment_70101", "id": "reaction_10752211", "reactome": "R-SPO-6800149", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6806829", "species_71284" ], "products": [ "species_6800127", "species_71285" ], "modifiers": [ [ "species_10752205", "catalyst" ] ], "additional_components": [ "Q9UT94", "SPAC323.05c", "Q09723", "SPAC31A2.02" ] }, "reaction_10735665": { "compartment": "compartment_70101", "id": "reaction_10735665", "reactome": "R-SPO-175983", "name": "COMT transfer CH3 from AdoMet to 3,4DHBNZ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_175977", "species_71284" ], "products": [ "species_71285", "species_175978" ], "modifiers": [ [ "species_10735662", "catalyst" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c" ] }, "reaction_10756481": { "compartment": "compartment_7660", "id": "reaction_10756481", "reactome": "R-SPO-8979071", "name": "KDM6B binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111793", "species_10743943" ], "products": [ "species_10743945" ], "modifiers": [], "additional_components": [ "SPBC23E6.09", "species_113531", "O60184", "SPBC23E6.09" ] }, "reaction_10743957": { "compartment": "compartment_70101", "id": "reaction_10743957", "reactome": "R-SPO-3225851", "name": "ROS oxidize thioredoxin and activate MAP3K5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1250243", "species_10743955" ], "products": [ "species_10732348", "species_10743953" ], "modifiers": [], "additional_components": [ "P28829", "SPBC1D7.05", "O94504", "SPBC12D12.07c", "SPBC12D12.07c", "SPBC1D7.05" ] }, "reaction_10739760": { "compartment": "compartment_70101", "id": "reaction_10739760", "reactome": "R-SPO-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739740" ], "products": [ "species_10739758" ], "modifiers": [], "additional_components": [ "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c" ] }, "reaction_10743960": { "compartment": "compartment_70101", "id": "reaction_10743960", "reactome": "R-SPO-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739826", "species_113592" ], "products": [ "species_29370", "species_10739740" ], "modifiers": [ [ "species_10743953", "catalyst" ] ], "additional_components": [ "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c", "SPBC1D7.05" ] }, "reaction_10743948": { "compartment": "compartment_7660", "id": "reaction_10743948", "reactome": "R-SPO-3222593", "name": "KDM6B demethylates H3K27me3 on p16INK4A promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743936", "species_113671" ], "products": [ "species_10743938", "species_159939" ], "modifiers": [ [ "species_10743945", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "species_113531", "O60184", "SPBC23E6.09" ] }, "reaction_10735519": { "compartment": "compartment_70101", "id": "reaction_10735519", "reactome": "R-SPO-174203", "name": "SCF-mediated degradation of Emi1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735512" ], "products": [ "species_10729165", "species_10735517", "species_10735506" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "Q9Y709", "SPBC409.05", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O13286", "SPAC144.13c", "P78972", "SPAC821.08c", "Q9Y709", "SPBC409.05", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10735515": { "compartment": "compartment_70101", "id": "reaction_10735515", "reactome": "R-SPO-174159", "name": "Ubiquitination of Emi1 by SCF-beta-TrCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729165", "species_10735510" ], "products": [ "species_10735512" ], "modifiers": [ [ "species_10735506", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9Y709", "SPBC409.05", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "Q9Y709", "SPBC409.05", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "P0CH06", "SPAC11G7.04", "Q9Y709", "SPBC409.05", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10734603": { "compartment": "compartment_70101", "id": "reaction_10734603", "reactome": "R-SPO-141429", "name": "Inactivation of APC/C via CDC20 sequestration", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734592", "species_10734597" ], "products": [ "species_10734601" ], "modifiers": [], "additional_components": [ "SPAC821.08c", "SPBC20F10.06", "P78972", "SPAC821.08c", "O14417", "SPBC20F10.06" ] }, "reaction_10735495": { "compartment": "compartment_70101", "id": "reaction_10735495", "reactome": "R-SPO-174124", "name": "Dephosphorylation of phospho-Cdh1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735485", "species_29356" ], "products": [ "species_111294", "species_10735473" ], "modifiers": [ [ "species_10735492", "catalyst" ] ], "additional_components": [ "SPAC144.13c", "SPAC144.13c", "Q9P7H1", "SPAC1782.09c" ] }, "reaction_10734605": { "compartment": "compartment_70101", "id": "reaction_10734605", "reactome": "R-SPO-141437", "name": "Formation of the MCC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734592", "species_10734582", "species_10734597", "species_10734587" ], "products": [ "species_10734599" ], "modifiers": [], "additional_components": [ "SPAC821.08c", "SPCC1322.12c", "SPBC20F10.06", "SPAC23H3.08c", "O94751", "SPCC1322.12c", "P78972", "SPAC821.08c", "O42860", "SPAC23H3.08c", "O14417", "SPBC20F10.06" ] }, "reaction_10737618": { "compartment": "compartment_70101", "id": "reaction_10737618", "reactome": "R-SPO-264615", "name": "Loading of acetylcholine in synaptic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_372511", "species_264643", "species_10737613" ], "products": [ "species_70106", "species_10737615" ], "modifiers": [ [ "species_10737597", "catalyst" ] ], "additional_components": [ "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "species_264643", "SPCC18.02" ] }, "reaction_10754876": { "compartment": "compartment_70101", "id": "reaction_10754876", "reactome": "R-SPO-8867667", "name": "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399" ], "products": [ "species_8868400" ], "modifiers": [ [ "species_10754873", "catalyst" ] ], "additional_components": [ "O13944", "SPAC23H4.01c", "O74178", "SPBC1271.12", "O14340", "SPBC2F12.05c" ] }, "reaction_10736277": { "compartment": "compartment_70101", "id": "reaction_10736277", "reactome": "R-SPO-193816", "name": "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192194", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193835" ], "modifiers": [ [ "species_10736206", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736267": { "compartment": "compartment_70101", "id": "reaction_10736267", "reactome": "R-SPO-193755", "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193745" ], "products": [ "species_29366", "species_193707" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736273": { "compartment": "compartment_70101", "id": "reaction_10736273", "reactome": "R-SPO-193789", "name": "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192189", "species_29360" ], "products": [ "species_70106", "species_73473", "species_193724" ], "modifiers": [ [ "species_10736206", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10755031": { "compartment": "compartment_70101", "id": "reaction_10755031", "reactome": "R-SPO-8868402", "name": "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8868399", "species_1806217" ], "products": [ "species_1806234", "species_8868393" ], "modifiers": [ [ "species_10755028", "catalyst" ] ], "additional_components": [ "O13944", "SPAC23H4.01c", "O14340", "SPBC2F12.05c" ] }, "reaction_10736211": { "compartment": "compartment_70101", "id": "reaction_10736211", "reactome": "R-SPO-192160", "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191980" ], "products": [ "species_29366", "species_192030" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736201": { "compartment": "compartment_70101", "id": "reaction_10736201", "reactome": "R-SPO-192067", "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192195" ], "products": [ "species_29366", "species_192064" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736269": { "compartment": "compartment_70101", "id": "reaction_10736269", "reactome": "R-SPO-193758", "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193760" ], "products": [ "species_29366", "species_213285" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736199": { "compartment": "compartment_70101", "id": "reaction_10736199", "reactome": "R-SPO-192036", "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192064" ], "products": [ "species_29366", "species_192087" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736275": { "compartment": "compartment_70101", "id": "reaction_10736275", "reactome": "R-SPO-193800", "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193829" ], "products": [ "species_29366", "species_193843" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736209": { "compartment": "compartment_70101", "id": "reaction_10736209", "reactome": "R-SPO-192097", "name": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192114", "species_29360" ], "products": [ "species_70106", "species_73473", "species_192136" ], "modifiers": [ [ "species_10736206", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736283": { "compartment": "compartment_70101", "id": "reaction_10736283", "reactome": "R-SPO-193841", "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193830" ], "products": [ "species_29366", "species_193842" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736279": { "compartment": "compartment_70101", "id": "reaction_10736279", "reactome": "R-SPO-193821", "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_9617026", "species_29364" ], "products": [ "species_29366", "species_193829" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736271": { "compartment": "compartment_70101", "id": "reaction_10736271", "reactome": "R-SPO-193781", "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193707" ], "products": [ "species_29366", "species_193728" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736188": { "compartment": "compartment_70101", "id": "reaction_10736188", "reactome": "R-SPO-192033", "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_192136" ], "products": [ "species_29366", "species_191980" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736168": { "compartment": "compartment_70101", "id": "reaction_10736168", "reactome": "R-SPO-191983", "name": "Cholesterol is hydroxylated to 25-hydroxycholesterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_176478", "species_29368" ], "products": [ "species_29366", "species_192148", "species_29356" ], "modifiers": [ [ "species_10736165", "catalyst" ] ], "additional_components": [ "species_113531", "Q9UUH4", "SPAC630.08c" ] }, "reaction_10736265": { "compartment": "compartment_70101", "id": "reaction_10736265", "reactome": "R-SPO-193746", "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193724" ], "products": [ "species_29366", "species_193760" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736281": { "compartment": "compartment_70101", "id": "reaction_10736281", "reactome": "R-SPO-193824", "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_193835", "species_29364" ], "products": [ "species_29366", "species_193830" ], "modifiers": [ [ "species_10736185", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736263": { "compartment": "compartment_876", "id": "reaction_10736263", "reactome": "R-SPO-193362", "name": "ABCB11 transports bile salts from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193416", "species_113592", "species_29356" ], "products": [ "species_29370", "species_193479", "species_29372" ], "modifiers": [ [ "species_10736260", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "CHEBI:16525", "CHEBI:28865", "CHEBI:36274", "CHEBI:17687", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274", "Q02592", "SPCC737.09c", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10756980": { "compartment": "compartment_70101", "id": "reaction_10756980", "reactome": "R-SPO-9020257", "name": "LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024893", "species_29356" ], "products": [ "species_9024879" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10757026": { "compartment": "compartment_70101", "id": "reaction_10757026", "reactome": "R-SPO-9024890", "name": "LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024873" ], "products": [ "species_9024886" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10734197": { "compartment": "compartment_12045", "id": "reaction_10734197", "reactome": "R-SPO-111883", "name": "Hydrolysis of phosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_140356", "species_428981" ], "modifiers": [ [ "species_10734192", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "species_429785", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10756212": { "compartment": "compartment_70101", "id": "reaction_10756212", "reactome": "R-SPO-8951727", "name": "cAMP binds PKA tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734228", "species_30389" ], "products": [ "species_10734230" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "P40376", "SPBC106.10", "P36600", "SPAC8C9.03", "species_30389", "P40376", "SPBC106.10" ] }, "reaction_10735214": { "compartment": "compartment_947587", "id": "reaction_10735214", "reactome": "R-SPO-167415", "name": "G-protein alpha subunit is inactivated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734141", "species_29420" ], "products": [ "species_29438", "species_10734240" ], "modifiers": [ [ "species_10734135", "catalyst" ] ], "additional_components": [ "species_29438", "Q04665", "SPAC23H3.13c", "species_29420", "Q04665", "SPAC23H3.13c", "SPAC23H3.13c" ] }, "reaction_10734214": { "compartment": "compartment_70101", "id": "reaction_10734214", "reactome": "R-SPO-111898", "name": "Phosphorylation of cPLA2 by ERK-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734211" ], "products": [ "species_29370", "species_10734190" ], "modifiers": [ [ "species_10733808", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "SPAC31G5.09c" ] }, "reaction_10734146": { "compartment": "compartment_70101", "id": "reaction_10734146", "reactome": "R-SPO-111879", "name": "PIP2 hydrolysis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_112275" ], "modifiers": [ [ "species_10734143", "catalyst" ] ], "additional_components": [ "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c" ] }, "reaction_10734242": { "compartment": "compartment_70101", "id": "reaction_10734242", "reactome": "R-SPO-112037", "name": "Inactivation of PLC beta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734143", "species_29356" ], "products": [ "species_10734124", "species_29372", "species_10734240" ], "modifiers": [], "additional_components": [ "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c", "SPAC22F8.11", "species_29420", "Q04665", "SPAC23H3.13c" ] }, "reaction_10739391": { "compartment": "compartment_70101", "id": "reaction_10739391", "reactome": "R-SPO-442749", "name": "CaMKK autophosphorylates in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10739383" ], "products": [ "species_113582", "species_10739388" ], "modifiers": [ [ "species_10739383", "catalyst" ] ], "additional_components": [ "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05" ] }, "reaction_10734194": { "compartment": "compartment_70101", "id": "reaction_10734194", "reactome": "R-SPO-111881", "name": "Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_10734190", "species_74016" ], "products": [ "species_10734192" ], "modifiers": [], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c", "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "species_429785", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10734234": { "compartment": "compartment_70101", "id": "reaction_10734234", "reactome": "R-SPO-111925", "name": "cAMP induces dissociation of inactive PKA tetramers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734230" ], "products": [ "species_10734226", "species_10734232" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "species_30389", "P40376", "SPBC106.10", "SPBC106.10", "P36600", "SPAC8C9.03", "species_30389" ] }, "reaction_10738861": { "compartment": "compartment_70101", "id": "reaction_10738861", "reactome": "R-SPO-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426030", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10738858", "catalyst" ] ], "additional_components": [ "SPCC5E4.05c" ] }, "reaction_10749913": { "compartment": "compartment_876", "id": "reaction_10749913", "reactome": "R-SPO-5694462", "name": "ABHD6,12 hydrolyse 3AG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694509", "species_29356" ], "products": [ "species_70106", "species_76116", "species_422506" ], "modifiers": [ [ "species_10749910", "catalyst" ] ], "additional_components": [ "SPAC22H12.03" ] }, "reaction_10743111": { "compartment": "compartment_70101", "id": "reaction_10743111", "reactome": "R-SPO-2408551", "name": "SeMet is converted to AdoSeMet by MAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5357707", "species_29356" ], "products": [ "species_5357652", "species_111294", "species_29372" ], "modifiers": [ [ "species_10735565", "catalyst" ] ], "additional_components": [ "O60198", "SPBC14F5.05c", "species_74126", "species_29926" ] }, "reaction_10756166": { "compartment": "compartment_70616", "id": "reaction_10756166", "reactome": "R-SPO-8949688", "name": "SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8949220", "species_2889072" ], "products": [ "species_8949232", "species_2889083" ], "modifiers": [ [ "species_10756163", "catalyst" ] ], "additional_components": [ "SPAC3A12.06c" ] }, "reaction_10729369": { "compartment": "compartment_70101", "id": "reaction_10729369", "reactome": "R-SPO-68948", "name": "Ubiquitinated Orc1 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729071" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "SPBC29A10.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10729069": { "compartment": "compartment_7660", "id": "reaction_10729069", "reactome": "R-SPO-68946", "name": "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728907", "species_10729044" ], "products": [ "species_10729047" ], "modifiers": [ [ "species_10729066", "catalyst" ] ], "additional_components": [ "SPBC29A10.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC29A10.15", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12" ] }, "reaction_10728940": { "compartment": "compartment_7660", "id": "reaction_10728940", "reactome": "R-SPO-68944", "name": "Orc1 is phosphorylated by cyclin A/CDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10728897" ], "products": [ "species_113582", "species_10728907", "species_10728911" ], "modifiers": [ [ "species_10728937", "catalyst" ] ], "additional_components": [ "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "SPBC29A10.15", "Q9Y794", "SPBP23A10.13", "O43114", "SPBC646.14c", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P41411", "SPBC14C8.07c", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "O74796", "SPBC2A9.12", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10729409": { "compartment": "compartment_7660", "id": "reaction_10729409", "reactome": "R-SPO-69005", "name": "Cdc6 protein is phosphorylated by CDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728714", "species_29358" ], "products": [ "species_113582", "species_10729384" ], "modifiers": [ [ "species_10729406", "catalyst" ] ], "additional_components": [ "SPBC14C8.07c", "SPBC14C8.07c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10729419": { "compartment": "compartment_70101", "id": "reaction_10729419", "reactome": "R-SPO-69016", "name": "Ubiquitinated Cdc6 is degraded by the proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729417" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P41411", "SPBC14C8.07c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10729421": { "compartment": "compartment_7660", "id": "reaction_10729421", "reactome": "R-SPO-69019", "name": "Mcm4,6,7 trimer forms and associates with the replication fork", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728861" ], "products": [ "species_10728857", "species_10728852", "species_10728828", "species_10728845" ], "modifiers": [], "additional_components": [ "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "SPAC1B2.05", "SPCC1682.02c", "SPBC4.04c", "P29458", "SPCC16A11.17", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10729073": { "compartment": "compartment_7660", "id": "reaction_10729073", "reactome": "R-SPO-68947", "name": "Ubiquitinated Orc1 enters the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729047" ], "products": [ "species_10729071" ], "modifiers": [], "additional_components": [ "SPBC29A10.15", "SPBC29A10.15" ] }, "reaction_10729413": { "compartment": "compartment_7660", "id": "reaction_10729413", "reactome": "R-SPO-69006", "name": "Phosphorylated Cdc6 is exported from the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729384" ], "products": [ "species_10729411" ], "modifiers": [], "additional_components": [ "SPBC14C8.07c", "SPBC14C8.07c" ] }, "reaction_10736391": { "compartment": "compartment_70101", "id": "reaction_10736391", "reactome": "R-SPO-196929", "name": "FLAD1 phosphorylates FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73524", "species_113592" ], "products": [ "species_29386", "species_111294" ], "modifiers": [ [ "species_10736388", "catalyst" ] ], "additional_components": [ "SPCC1235.04c" ] }, "reaction_10736411": { "compartment": "compartment_70101", "id": "reaction_10736411", "reactome": "R-SPO-196964", "name": "RFK:Mg2+ phosphorylates RIB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196931" ], "products": [ "species_29370", "species_73524" ], "modifiers": [ [ "species_10736408", "catalyst" ] ], "additional_components": [ "O74866", "SPCC18.16c", "species_29926" ] }, "reaction_10736401": { "compartment": "compartment_70101", "id": "reaction_10736401", "reactome": "R-SPO-196955", "name": "2xENPP1 hydrolyzes FAD to FMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29386", "species_29356" ], "products": [ "species_73524", "species_76577" ], "modifiers": [ [ "species_10736398", "catalyst" ] ], "additional_components": [ "O94323", "SPBC725.05c" ] }, "reaction_10738598": { "compartment": "compartment_876", "id": "reaction_10738598", "reactome": "R-SPO-418309", "name": "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016" ], "products": [ "species_74112" ], "modifiers": [ [ "species_10738589", "catalyst" ] ], "additional_components": [ "SPAPB2B4.04c" ] }, "reaction_10746051": { "compartment": "compartment_876", "id": "reaction_10746051", "reactome": "R-SPO-5617178", "name": "ATP2B4 binds to NOS1, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738595", "species_10738606" ], "products": [ "species_10746049" ], "modifiers": [], "additional_components": [ "SPAPB2B4.04c", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "Q9HDW7", "SPAPB2B4.04c", "P36587", "SPBC29A10.01" ] }, "reaction_10745982": { "compartment": "compartment_70101", "id": "reaction_10745982", "reactome": "R-SPO-5607721", "name": "Activation of NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738454" ], "products": [ "species_10738454" ], "modifiers": [], "additional_components": [ "SPAC1006.09", "SPAC1006.09" ] }, "reaction_10746751": { "compartment": "compartment_70101", "id": "reaction_10746751", "reactome": "R-SPO-5668545", "name": "NIK autophosphorylates on T559", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10738454" ], "products": [ "species_29370", "species_10746748" ], "modifiers": [ [ "species_10738454", "catalyst" ] ], "additional_components": [ "SPAC1006.09", "SPAC1006.09", "SPAC1006.09" ] }, "reaction_10739639": { "compartment": "compartment_70101", "id": "reaction_10739639", "reactome": "R-SPO-446877", "name": "TRAF6 is K63 poly-ubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739630" ], "products": [ "species_10739636" ], "modifiers": [ [ "species_10739630", "catalyst" ] ], "additional_components": [ "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "O13924", "SPAC23C4.03", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746745": { "compartment": "compartment_70101", "id": "reaction_10746745", "reactome": "R-SPO-5668520", "name": "26Sproteasome degrades K48polyUb-NIK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746743" ], "products": [], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "SPAC1006.09", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10735267": { "compartment": "compartment_7660", "id": "reaction_10735267", "reactome": "R-SPO-168053", "name": "Phosphorylated MAPKs phosphorylate ATF-2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10735231" ], "products": [ "species_113582", "species_10735245" ], "modifiers": [ [ "species_10735264", "catalyst" ] ], "additional_components": [ "P52890", "SPBC29B5.01", "P78962", "SPBC2F12.09c", "Q09771", "SPAC22F3.02", "P52890", "SPBC29B5.01", "P78962", "SPBC2F12.09c", "Q09771", "SPAC22F3.02", "Q09892", "SPAC24B11.06c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10739950": { "compartment": "compartment_70101", "id": "reaction_10739950", "reactome": "R-SPO-451418", "name": "Pellino ubiquitinates IRAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739939" ], "products": [ "species_10739947" ], "modifiers": [ [ "species_10739939", "catalyst" ] ], "additional_components": [ "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "O13924", "SPAC23C4.03", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "O13924", "SPAC23C4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10736765": { "compartment": "compartment_7660", "id": "reaction_10736765", "reactome": "R-SPO-199959", "name": "ERKs are inactivated by protein phosphatase 2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10736632" ], "products": [ "species_113550", "species_10736739" ], "modifiers": [ [ "species_10736762", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "Q10428", "SPCC188.02", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c" ] }, "reaction_10736635": { "compartment": "compartment_7660", "id": "reaction_10736635", "reactome": "R-SPO-198756", "name": "ERK1/2 phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10736617" ], "products": [ "species_113582", "species_10736623" ], "modifiers": [ [ "species_10736632", "catalyst" ] ], "additional_components": [ "SPCC4G3.08", "SPCC4G3.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10737238": { "compartment": "compartment_7660", "id": "reaction_10737238", "reactome": "R-SPO-203797", "name": "ERKs are inactivated by dual-specific phosphatases (DUSPs)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10736632" ], "products": [ "species_113550", "species_10736739" ], "modifiers": [ [ "species_10737231", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPBC1685.01" ] }, "reaction_10736626": { "compartment": "compartment_7660", "id": "reaction_10736626", "reactome": "R-SPO-198669", "name": "p38MAPK phosphorylates MSK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10736617" ], "products": [ "species_113582", "species_10736623" ], "modifiers": [ [ "species_10735252", "catalyst" ] ], "additional_components": [ "SPCC4G3.08", "SPCC4G3.08", "SPAC24B11.06c" ] }, "reaction_10739512": { "compartment": "compartment_12045", "id": "reaction_10739512", "reactome": "R-SPO-446195", "name": "DOLK phosphorylates DCHOL to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449221", "species_110614" ], "products": [ "species_449299", "species_110094" ], "modifiers": [ [ "species_10739509", "catalyst" ] ], "additional_components": [ "SPCC63.10c" ] }, "reaction_10744801": { "compartment": "compartment_12045", "id": "reaction_10744801", "reactome": "R-SPO-4419979", "name": "SRD5A3 reduces pPNOL to DCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_4419981" ], "products": [ "species_29366", "species_449221" ], "modifiers": [ [ "species_10744798", "catalyst" ] ], "additional_components": [ "SPAC7D4.09c" ] }, "reaction_10739528": { "compartment": "compartment_12045", "id": "reaction_10739528", "reactome": "R-SPO-446200", "name": "DOLPP1 dephosphorylates DOLDP to DOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449744", "species_29356" ], "products": [ "species_449299", "species_29372" ], "modifiers": [ [ "species_10739525", "catalyst" ] ], "additional_components": [ "SPBC530.12c" ] }, "reaction_10736144": { "compartment": "compartment_70101", "id": "reaction_10736144", "reactome": "R-SPO-191414", "name": "MVD decarboxylates MVA5PP to IPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191403" ], "products": [ "species_29370", "species_191362", "species_113528", "species_29372" ], "modifiers": [ [ "species_10736141", "catalyst" ] ], "additional_components": [ "O13963", "SPAC24C9.03" ] }, "reaction_10744793": { "compartment": "compartment_12045", "id": "reaction_10744793", "reactome": "R-SPO-4419978", "name": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_4419987", "species_191362" ], "products": [ "species_4419982" ], "modifiers": [ [ "species_10744790", "catalyst" ] ], "additional_components": [ "O14171", "SPAC4D7.04c", "Q9Y7K8", "SPBC2A9.06c" ] }, "reaction_10739410": { "compartment": "compartment_70101", "id": "reaction_10739410", "reactome": "R-SPO-445079", "name": "Phosphorylation of L1 by ERK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738464", "species_113592", "species_10733808" ], "products": [ "species_29370", "species_10739408" ], "modifiers": [ [ "species_10733808", "catalyst" ] ], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "SPAC31G5.09c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "P27638", "SPAC31G5.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "SPAC31G5.09c" ] }, "reaction_10733813": { "compartment": "compartment_70101", "id": "reaction_10733813", "reactome": "R-SPO-109862", "name": "MAP2K2 phosphorylates MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10733780" ], "products": [ "species_29370", "species_10733810" ], "modifiers": [ [ "species_10733780", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13" ] }, "reaction_10738466": { "compartment": "compartment_17940", "id": "reaction_10738466", "reactome": "R-SPO-392749", "name": "Transport of L1 into endosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738464" ], "products": [ "species_10738464" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10733803": { "compartment": "compartment_70101", "id": "reaction_10733803", "reactome": "R-SPO-109860", "name": "MAP2K1 phosphorylates MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10733770" ], "products": [ "species_29370", "species_10733794" ], "modifiers": [ [ "species_10733770", "catalyst" ], [ "species_10733799", "inhibitor" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "SPAC1D4.13" ] }, "reaction_10740265": { "compartment": "compartment_876", "id": "reaction_10740265", "reactome": "R-SPO-555065", "name": "Formation of clathrin coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735803", "species_29438", "species_10740252" ], "products": [ "species_10738464", "species_29372", "species_29420" ], "modifiers": [ [ "species_10740262", "catalyst" ] ], "additional_components": [ "SPBC119.05c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "O43125", "SPBC119.05c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c" ] }, "reaction_10742224": { "compartment": "compartment_70101", "id": "reaction_10742224", "reactome": "R-SPO-1614583", "name": "PXLP-K212-CTH cleaves L-Cystathionine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614518", "species_29356" ], "products": [ "species_29382", "species_936714", "species_111707" ], "modifiers": [ [ "species_10742218", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10744044": { "compartment": "compartment_70101", "id": "reaction_10744044", "reactome": "R-SPO-3299753", "name": "CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744037" ], "products": [ "species_10744041", "species_10744022" ], "modifiers": [ [ "species_10744037", "catalyst" ] ], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "P28758", "SPAC821.10c", "species_442320", "species_437295", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552" ] }, "reaction_10744457": { "compartment": "compartment_70101", "id": "reaction_10744457", "reactome": "R-SPO-3697882", "name": "PRDX5 reduces peroxynitrite to nitrite using TXN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1222481", "species_10732350" ], "products": [ "species_10732348", "species_29356", "species_1222379" ], "modifiers": [ [ "species_10744099", "catalyst" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "SPCC330.06c" ] }, "reaction_10744104": { "compartment": "compartment_70101", "id": "reaction_10744104", "reactome": "R-SPO-3341343", "name": "PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29408", "species_10732350" ], "products": [ "species_10732348", "species_29356" ], "modifiers": [ [ "species_10744101", "catalyst" ] ], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c", "O14313", "SPCC330.06c", "O74887", "SPCC576.03c" ] }, "reaction_10744454": { "compartment": "compartment_70101", "id": "reaction_10744454", "reactome": "R-SPO-3697860", "name": "SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744035", "species_10744450" ], "products": [ "species_10744452" ], "modifiers": [], "additional_components": [ "species_442320", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552" ] }, "reaction_10756210": { "compartment": "compartment_70101", "id": "reaction_10756210", "reactome": "R-SPO-8951723", "name": "2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744452" ], "products": [ "species_10744037" ], "modifiers": [], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552", "P28758", "SPAC821.10c", "species_442320", "Q10357", "SPAC22E12.04", "CHEBI:49552" ] }, "reaction_10744025": { "compartment": "compartment_70101", "id": "reaction_10744025", "reactome": "R-SPO-3299691", "name": "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_1222424" ], "products": [ "species_29408", "species_29368" ], "modifiers": [ [ "species_10744022", "catalyst" ] ], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "species_437295" ] }, "reaction_10744083": { "compartment": "compartment_70616", "id": "reaction_10744083", "reactome": "R-SPO-3341294", "name": "Superoxide reduces cytochrome c", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_10734930" ], "products": [ "species_189461", "species_10734928" ], "modifiers": [], "additional_components": [ "P00046", "SPCC191.07", "CHEBI:38574", "P00046", "SPCC191.07", "CHEBI:38573" ] }, "reaction_10744079": { "compartment": "compartment_5460", "id": "reaction_10744079", "reactome": "R-SPO-3323079", "name": "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_1655882", "species_113529" ], "products": [ "species_113563", "species_1655887" ], "modifiers": [ [ "species_10744076", "catalyst" ] ], "additional_components": [ "P78965", "SPBC17A3.07", "species_113596" ] }, "reaction_10744015": { "compartment": "compartment_984", "id": "reaction_10744015", "reactome": "R-SPO-3299682", "name": "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299686", "species_351626" ], "products": [ "species_351629", "species_352327" ], "modifiers": [ [ "species_10744012", "catalyst" ] ], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "species_437295" ] }, "reaction_10744004": { "compartment": "compartment_5460", "id": "reaction_10744004", "reactome": "R-SPO-3299680", "name": "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3299683", "species_113529" ], "products": [ "species_113533", "species_1614617" ], "modifiers": [ [ "species_10744001", "catalyst" ] ], "additional_components": [ "Q9UQX0", "SPAC1486.01", "species_113527" ] }, "reaction_10733436": { "compartment": "compartment_17951", "id": "reaction_10733436", "reactome": "R-SPO-76031", "name": "2 H2O2 => O2 + 2 H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113575" ], "products": [ "species_141343", "species_113535" ], "modifiers": [ [ "species_10733433", "catalyst" ] ], "additional_components": [ "species_189444", "P55306", "SPCC757.07c", "species_113600" ] }, "reaction_10744568": { "compartment": "compartment_17927", "id": "reaction_10744568", "reactome": "R-SPO-3777112", "name": "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3341308", "species_163953" ], "products": [ "species_189481", "species_189461" ], "modifiers": [ [ "species_10744565", "catalyst" ] ], "additional_components": [ "species_442320", "P28758", "SPAC821.10c", "species_437295" ] }, "reaction_10745062": { "compartment": "compartment_17963", "id": "reaction_10745062", "reactome": "R-SPO-4837364", "name": "Secretion of SOD3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745060" ], "products": [ "species_10744012" ], "modifiers": [], "additional_components": [ "P28758", "SPAC821.10c", "species_442320", "species_437295", "P28758", "SPAC821.10c", "species_442320", "species_437295" ] }, "reaction_10746853": { "compartment": "compartment_70101", "id": "reaction_10746853", "reactome": "R-SPO-5674385", "name": "p-T,Y MAPKs dimerize", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741495" ], "products": [ "species_10744304" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10757290": { "compartment": "compartment_70101", "id": "reaction_10757290", "reactome": "R-SPO-9610166", "name": "p-T,Y MAPK dimers translocate to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744304" ], "products": [ "species_10736632" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10739876": { "compartment": "compartment_70101", "id": "reaction_10739876", "reactome": "R-SPO-450517", "name": "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739853", "species_450523" ], "products": [ "species_10739855" ], "modifiers": [], "additional_components": [ "SPBC1718.07c", "P47979", "SPBC1718.07c" ] }, "reaction_10739870": { "compartment": "compartment_70101", "id": "reaction_10739870", "reactome": "R-SPO-450490", "name": "Protein Kinase B/Akt phosphorylates BRF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739855", "species_113592" ], "products": [ "species_29370", "species_10739867" ], "modifiers": [ [ "species_10736495", "catalyst" ] ], "additional_components": [ "P47979", "SPBC1718.07c", "P47979", "SPBC1718.07c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10738965": { "compartment": "compartment_876", "id": "reaction_10738965", "reactome": "R-SPO-427570", "name": "Group 3 - Selective Cl- transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188972" ], "products": [ "species_352022" ], "modifiers": [ [ "species_10738962", "catalyst" ] ], "additional_components": [ "O59782", "SPCC320.05" ] }, "reaction_10738848": { "compartment": "compartment_171062", "id": "reaction_10738848", "reactome": "R-SPO-425983", "name": "SLC9A6,7 exchange Na+ for H+ across the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425978", "species_83910" ], "products": [ "species_70106", "species_425971" ], "modifiers": [ [ "species_10738845", "catalyst" ] ], "additional_components": [ "O13726", "SPAC15A10.06" ] }, "reaction_10738839": { "compartment": "compartment_172574", "id": "reaction_10738839", "reactome": "R-SPO-425965", "name": "SLC9A9 exchanges Na+ for H+ across the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_83910", "species_425999" ], "products": [ "species_70106", "species_425977" ], "modifiers": [ [ "species_10738836", "catalyst" ] ], "additional_components": [ "SPAC15A10.06" ] }, "reaction_10746330": { "compartment": "compartment_70101", "id": "reaction_10746330", "reactome": "R-SPO-5627802", "name": "SLC26A4 transports I- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209785" ], "products": [ "species_209818" ], "modifiers": [ [ "species_10746327", "catalyst" ] ], "additional_components": [ "SPCC320.05" ] }, "reaction_10738878": { "compartment": "compartment_876", "id": "reaction_10738878", "reactome": "R-SPO-426130", "name": "SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972" ], "products": [ "species_83910", "species_352022" ], "modifiers": [ [ "species_10738875", "catalyst" ] ], "additional_components": [ "SPBC18H10.16" ] }, "reaction_10754356": { "compartment": "compartment_70101", "id": "reaction_10754356", "reactome": "R-SPO-8855062", "name": "SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162252", "species_71284" ], "products": [ "species_71285", "species_2162265" ], "modifiers": [ [ "species_10754353", "catalyst" ] ], "additional_components": [ "SPAC12B10.09" ] }, "reaction_10738984": { "compartment": "compartment_17938", "id": "reaction_10738984", "reactome": "R-SPO-428007", "name": "Proton-coupled histidine and di-peptide cotransport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427984", "species_428040" ], "products": [ "species_70106", "species_428003" ], "modifiers": [ [ "species_10738979", "catalyst" ] ], "additional_components": [ "CHEBI:90799", "CHEBI:32513", "CHEBI:32513", "CHEBI:46761", "SPBC13A2.04c" ] }, "reaction_10738956": { "compartment": "compartment_876", "id": "reaction_10738956", "reactome": "R-SPO-427555", "name": "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648", "species_351626" ], "products": [ "species_70106", "species_174375" ], "modifiers": [ [ "species_10738953", "catalyst" ] ], "additional_components": [ "O59782", "SPCC320.05" ] }, "reaction_10755472": { "compartment": "compartment_70101", "id": "reaction_10755472", "reactome": "R-SPO-8875623", "name": "SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29404" ], "products": [ "species_113552", "species_113529" ], "modifiers": [ [ "species_10755469", "catalyst" ] ], "additional_components": [ "Q9P3T7", "SPAC328.09" ] }, "reaction_10755488": { "compartment": "compartment_70101", "id": "reaction_10755488", "reactome": "R-SPO-8875871", "name": "SLC26A11 transports SO4(2-) from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_427648" ], "products": [ "species_174375" ], "modifiers": [ [ "species_10755485", "catalyst" ] ], "additional_components": [ "SPAC869.05c" ] }, "reaction_10738819": { "compartment": "compartment_876", "id": "reaction_10738819", "reactome": "R-SPO-425822", "name": "K+-independent Li+/Ca2+ exchanger transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_425815" ], "products": [ "species_425810", "species_74112" ], "modifiers": [ [ "species_10738816", "catalyst" ] ], "additional_components": [ "SPAC3A12.06c" ] }, "reaction_10738974": { "compartment": "compartment_876", "id": "reaction_10738974", "reactome": "R-SPO-427666", "name": "SLC26A3,6 exchange Cl- for HCO3-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111627", "species_188972" ], "products": [ "species_352022", "species_425425" ], "modifiers": [ [ "species_10738971", "catalyst" ] ], "additional_components": [ "O59782", "SPCC320.05" ] }, "reaction_10738873": { "compartment": "compartment_876", "id": "reaction_10738873", "reactome": "R-SPO-426086", "name": "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74113", "species_188972", "species_74126" ], "products": [ "species_29804", "species_83910", "species_352022" ], "modifiers": [ [ "species_10738870", "catalyst" ] ], "additional_components": [ "O60146", "SPBC18H10.16" ] }, "reaction_10738853": { "compartment": "compartment_20699", "id": "reaction_10738853", "reactome": "R-SPO-426015", "name": "Na+/H+ exchanger transport (at trans-golgi membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_425969", "species_83910" ], "products": [ "species_70106", "species_425958" ], "modifiers": [ [ "species_10738850", "catalyst" ] ], "additional_components": [ "SPAC15A10.06" ] }, "reaction_10753176": { "compartment": "compartment_70101", "id": "reaction_10753176", "reactome": "R-SPO-6809778", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6809774", "species_29356" ], "products": [ "species_422529", "species_29372" ], "modifiers": [ [ "species_10753168", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10753572": { "compartment": "compartment_876", "id": "reaction_10753572", "reactome": "R-SPO-6814797", "name": "ENPP6 hydrolyzes lysophosphatidylcholine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_2239407" ], "products": [ "species_6814794", "species_6814795" ], "modifiers": [ [ "species_10753569", "catalyst" ] ], "additional_components": [ "SPBC725.05c" ] }, "reaction_10753131": { "compartment": "compartment_70101", "id": "reaction_10753131", "reactome": "R-SPO-6809254", "name": "MTMR8 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753127", "species_10753125" ], "products": [ "species_10753129" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742441": { "compartment": "compartment_876", "id": "reaction_10742441", "reactome": "R-SPO-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10742438", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "O13819", "SPAC19A8.03" ] }, "reaction_10753468": { "compartment": "compartment_7660", "id": "reaction_10753468", "reactome": "R-SPO-6811522", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_6810408" ], "products": [ "species_113582", "species_6810412" ], "modifiers": [ [ "species_10753465", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14" ] }, "reaction_10742467": { "compartment": "compartment_12045", "id": "reaction_10742467", "reactome": "R-SPO-1676124", "name": "PI4P is dephosphorylated to PI by SACM1L at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806234", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10742464", "catalyst" ] ], "additional_components": [ "SPBC19F5.03" ] }, "reaction_10753148": { "compartment": "compartment_876", "id": "reaction_10753148", "reactome": "R-SPO-6809320", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10753145", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742498": { "compartment": "compartment_20699", "id": "reaction_10742498", "reactome": "R-SPO-1676185", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10742495", "catalyst" ] ], "additional_components": [ "Q9UT42", "SPAC343.19", "Q9USR3", "SPBC577.06c" ] }, "reaction_10742443": { "compartment": "compartment_172574", "id": "reaction_10742443", "reactome": "R-SPO-1676024", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806195" ], "products": [ "species_29370", "species_1806198" ], "modifiers": [ [ "species_10742410", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "species_113527" ] }, "reaction_10742425": { "compartment": "compartment_20699", "id": "reaction_10742425", "reactome": "R-SPO-1675961", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806159" ], "modifiers": [ [ "species_10742410", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "species_113527" ] }, "reaction_10753515": { "compartment": "compartment_12045", "id": "reaction_10753515", "reactome": "R-SPO-6814254", "name": "PNPLA6 hydrolyzes LysoPtdCho", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6814253", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10753512", "catalyst" ] ], "additional_components": [ "SPCC4B3.04c" ] }, "reaction_10753151": { "compartment": "compartment_876", "id": "reaction_10753151", "reactome": "R-SPO-6809325", "name": "PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_29356" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10753145", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742449": { "compartment": "compartment_876", "id": "reaction_10742449", "reactome": "R-SPO-1676082", "name": "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742382": { "compartment": "compartment_12045", "id": "reaction_10742382", "reactome": "R-SPO-1675813", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_29370", "species_1806234" ], "modifiers": [ [ "species_10742379", "catalyst" ] ], "additional_components": [ "Q9UT42", "SPAC343.19", "Q9USR3", "SPBC577.06c" ] }, "reaction_10742353": { "compartment": "compartment_876", "id": "reaction_10742353", "reactome": "R-SPO-1675780", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_392417" ], "modifiers": [ [ "species_10742348", "catalyst" ] ], "additional_components": [ "SPAC343.19" ] }, "reaction_10742476": { "compartment": "compartment_171062", "id": "reaction_10742476", "reactome": "R-SPO-1676141", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10742451", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10753164": { "compartment": "compartment_171062", "id": "reaction_10753164", "reactome": "R-SPO-6809720", "name": "PI3P is dephosphorylated to PI by MTM1:MTMR12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806200" ], "products": [ "species_1806199", "species_29372" ], "modifiers": [ [ "species_10753155", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742473": { "compartment": "compartment_876", "id": "reaction_10742473", "reactome": "R-SPO-1676134", "name": "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_1806224" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742423": { "compartment": "compartment_876", "id": "reaction_10742423", "reactome": "R-SPO-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_29356" ], "products": [ "species_202247", "species_29372" ], "modifiers": [ [ "species_10742418", "catalyst" ] ], "additional_components": [ "SPBC577.13" ] }, "reaction_10753157": { "compartment": "compartment_70101", "id": "reaction_10753157", "reactome": "R-SPO-6809680", "name": "MTMR12 binds MTM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753153", "species_10742358" ], "products": [ "species_10753155" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742462": { "compartment": "compartment_20699", "id": "reaction_10742462", "reactome": "R-SPO-1676114", "name": "PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806159", "species_29356" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10742459", "catalyst" ] ], "additional_components": [ "SPBC19F5.03" ] }, "reaction_10742488": { "compartment": "compartment_20699", "id": "reaction_10742488", "reactome": "R-SPO-1676152", "name": "PI4KB binds to ARF1/3:GTP at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742486", "species_10742399" ], "products": [ "species_10742401" ], "modifiers": [], "additional_components": [ "SPAC22E12.16c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "P36579", "SPBC4F6.18c", "Q10366", "SPAC22E12.16c", "CHEBI:15996" ] }, "reaction_10742508": { "compartment": "compartment_20699", "id": "reaction_10742508", "reactome": "R-SPO-1676204", "name": "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806230", "species_29356" ], "products": [ "species_1806217", "species_29372" ], "modifiers": [ [ "species_10742503", "catalyst" ] ], "additional_components": [ "SPBC609.02" ] }, "reaction_10742454": { "compartment": "compartment_171062", "id": "reaction_10742454", "reactome": "R-SPO-1676105", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806205", "species_29356" ], "products": [ "species_1806259", "species_29372" ], "modifiers": [ [ "species_10742451", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742501": { "compartment": "compartment_876", "id": "reaction_10742501", "reactome": "R-SPO-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806240", "species_29372" ], "modifiers": [ [ "species_10742438", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "O13819", "SPAC19A8.03" ] }, "reaction_10753170": { "compartment": "compartment_70101", "id": "reaction_10753170", "reactome": "R-SPO-6809764", "name": "SBF1 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742360", "species_10753166" ], "products": [ "species_10753168" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742484": { "compartment": "compartment_876", "id": "reaction_10742484", "reactome": "R-SPO-1676149", "name": "PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_202247", "species_29356" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10736691", "catalyst" ] ], "additional_components": [ "SPBC609.02" ] }, "reaction_10742481": { "compartment": "compartment_876", "id": "reaction_10742481", "reactome": "R-SPO-1676145", "name": "PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806276", "species_113592" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10742478", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14" ] }, "reaction_10742430": { "compartment": "compartment_876", "id": "reaction_10742430", "reactome": "R-SPO-1675988", "name": "PI4P is dephosphorylated to PI by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_392417" ], "products": [ "species_426658", "species_29372" ], "modifiers": [ [ "species_10742387", "catalyst" ] ], "additional_components": [ "SPBC2G2.02" ] }, "reaction_10742320": { "compartment": "compartment_876", "id": "reaction_10742320", "reactome": "R-SPO-1675773", "name": "PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_202247" ], "products": [ "species_29370", "species_179838" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742404": { "compartment": "compartment_20699", "id": "reaction_10742404", "reactome": "R-SPO-1675883", "name": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524146", "species_113592" ], "products": [ "species_29370", "species_1806217" ], "modifiers": [ [ "species_10742401", "catalyst" ] ], "additional_components": [ "P36579", "SPBC4F6.18c", "Q10366", "SPAC22E12.16c", "CHEBI:15996" ] }, "reaction_10736694": { "compartment": "compartment_70101", "id": "reaction_10736694", "reactome": "R-SPO-199456", "name": "PTEN dephosphorylates PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_29356" ], "products": [ "species_29372", "species_179856" ], "modifiers": [ [ "species_10736691", "catalyst" ] ], "additional_components": [ "SPBC609.02" ] }, "reaction_10742446": { "compartment": "compartment_172574", "id": "reaction_10742446", "reactome": "R-SPO-1676065", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1806289" ], "products": [ "species_1806212", "species_29372" ], "modifiers": [ [ "species_10742366", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742392": { "compartment": "compartment_876", "id": "reaction_10742392", "reactome": "R-SPO-1675836", "name": "PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806224", "species_29356" ], "products": [ "species_1806276", "species_29372" ], "modifiers": [ [ "species_10742387", "catalyst" ] ], "additional_components": [ "SPBC2G2.02" ] }, "reaction_10742372": { "compartment": "compartment_876", "id": "reaction_10742372", "reactome": "R-SPO-1675810", "name": "PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426658" ], "products": [ "species_29370", "species_1806240" ], "modifiers": [ [ "species_10742313", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10742413": { "compartment": "compartment_171062", "id": "reaction_10742413", "reactome": "R-SPO-1675939", "name": "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806200" ], "modifiers": [ [ "species_10742410", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "species_113527" ] }, "reaction_10742369": { "compartment": "compartment_172574", "id": "reaction_10742369", "reactome": "R-SPO-1675795", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806198", "species_29356" ], "products": [ "species_1806195", "species_29372" ], "modifiers": [ [ "species_10742366", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10753143": { "compartment": "compartment_70101", "id": "reaction_10753143", "reactome": "R-SPO-6809309", "name": "MTMR6 binds MTMR9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753127", "species_10742436" ], "products": [ "species_10753141" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10753161": { "compartment": "compartment_70101", "id": "reaction_10753161", "reactome": "R-SPO-6809707", "name": "MTMR12 binds MTMR2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753153", "species_10742360" ], "products": [ "species_10753159" ], "modifiers": [], "additional_components": [ "SPAC19A8.03", "SPAC19A8.03", "O13819", "SPAC19A8.03" ] }, "reaction_10742493": { "compartment": "compartment_876", "id": "reaction_10742493", "reactome": "R-SPO-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_29372", "species_392417" ], "modifiers": [ [ "species_10742490", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "Q9USQ6", "SPBC577.13" ] }, "reaction_10742343": { "compartment": "compartment_876", "id": "reaction_10742343", "reactome": "R-SPO-1675776", "name": "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1806240" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10742340", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14" ] }, "reaction_10753173": { "compartment": "compartment_70101", "id": "reaction_10753173", "reactome": "R-SPO-6809777", "name": "PI3P is dephosphorylated to PI by MTMR2:SBF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030", "species_29356" ], "products": [ "species_426639", "species_29372" ], "modifiers": [ [ "species_10753168", "catalyst" ] ], "additional_components": [ "O13819", "SPAC19A8.03" ] }, "reaction_10742470": { "compartment": "compartment_20699", "id": "reaction_10742470", "reactome": "R-SPO-1676133", "name": "PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806217" ], "products": [ "species_1524146", "species_29372" ], "modifiers": [ [ "species_10742459", "catalyst" ] ], "additional_components": [ "SPBC19F5.03" ] }, "reaction_10742427": { "compartment": "compartment_171062", "id": "reaction_10742427", "reactome": "R-SPO-1675974", "name": "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1806199", "species_113592" ], "products": [ "species_29370", "species_1806180" ], "modifiers": [ [ "species_10742348", "catalyst" ] ], "additional_components": [ "SPAC343.19" ] }, "reaction_10732994": { "compartment": "compartment_7660", "id": "reaction_10732994", "reactome": "R-SPO-75079", "name": "Formation of AT-AC C complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732990" ], "products": [ "species_10732982", "species_10732992" ], "modifiers": [], "additional_components": [ "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "Q9UUI3", "SPAC22F8.10c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q10178", "SPAC27F1.09c", "O74825", "SPBC337.14", "O94620", "SPBC1289.11", "Q9UUC6", "SPBC19C2.14", "Q02061", "SPAC23G3.01", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "Q9P7R6", "SPBC211.05", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05", "Q9UUC6", "SPBC19C2.14", "Q10163", "SPAC26A3.08", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "Q9USZ3", "SPBC11G11.06c", "O14036", "SPAC2C4.03c", "O74966", "SPBC4B4.05", "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "P36594", "SPBC28F2.12", "Q9UUI3", "SPAC22F8.10c", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q10178", "SPAC27F1.09c", "O94620", "SPBC1289.11", "Q02061", "SPAC23G3.01", "Q9UUC6", "SPBC19C2.14", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "P48011", "SPBC19C2.03", "Q9P7R6", "SPBC211.05", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05" ] }, "reaction_10732996": { "compartment": "compartment_7660", "id": "reaction_10732996", "reactome": "R-SPO-75082", "name": "ATAC spliceosome mediated Lariat formation,5' splice site cleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732992" ], "products": [ "species_10732992" ], "modifiers": [], "additional_components": [ "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "P36594", "SPBC28F2.12", "Q9UUI3", "SPAC22F8.10c", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q10178", "SPAC27F1.09c", "O94620", "SPBC1289.11", "Q02061", "SPAC23G3.01", "Q9UUC6", "SPBC19C2.14", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "P48011", "SPBC19C2.03", "Q9P7R6", "SPBC211.05", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05", "O59670", "SPBC29A3.07c", "Q10163", "SPAC26A3.08", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9USZ3", "SPBC11G11.06c", "Q9USY2", "SPBC1861.04c", "O14459", "SPACUNK4.06c", "Q9UTT2", "SPAPJ698.03c", "P36594", "SPBC28F2.12", "Q9UUI3", "SPAC22F8.10c", "Q09191", "SPAC23C4.15", "O94408", "SPCC1620.01c", "Q9Y7T7", "SPCC63.11", "O42661", "SPAC27D7.07c", "O59734", "SPBC3E7.14", "O74690", "SPAC607.03c", "O14187", "SPAC4F8.12c", "P87123", "SPAC3A12.07", "Q9HEQ9", "SPBC660.11", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q10178", "SPAC27F1.09c", "O94620", "SPBC1289.11", "Q02061", "SPAC23G3.01", "Q9UUC6", "SPBC19C2.14", "P87215", "SPCC16A11.05c", "O94416", "SPCC1620.09c", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "O14036", "SPAC2C4.03c", "O13877", "SPAC1B3.12c", "Q9UT24", "SPAC9.03c", "O94316", "SPBC215.12", "P48011", "SPBC19C2.03", "Q9P7R6", "SPBC211.05", "Q92399", "SPBC14C8.12", "O14253", "SPAC6G10.07", "Q12381", "SPBC6B1.07", "O74966", "SPBC4B4.05" ] }, "reaction_10729563": { "compartment": "compartment_70101", "id": "reaction_10729563", "reactome": "R-SPO-69191", "name": "Formation of Cyclin E:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729559", "species_10729541" ], "products": [ "species_10729561" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "SPBC11B10.09", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10735839": { "compartment": "compartment_7660", "id": "reaction_10735839", "reactome": "R-SPO-188350", "name": "CAK-mediated phosphorylation of Cyclin E:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10729567" ], "products": [ "species_113582", "species_10729404" ], "modifiers": [ [ "species_10732457", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07" ] }, "reaction_10729580": { "compartment": "compartment_7660", "id": "reaction_10729580", "reactome": "R-SPO-69199", "name": "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729572", "species_113518" ], "products": [ "species_113550", "species_10729567" ], "modifiers": [ [ "species_10729577", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "SPAC24H6.05" ] }, "reaction_10734745": { "compartment": "compartment_13231", "id": "reaction_10734745", "reactome": "R-SPO-157906", "name": "Translocation of Cyclin E:Cdk2 complex to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729561" ], "products": [ "species_10729567" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10747656": { "compartment": "compartment_7660", "id": "reaction_10747656", "reactome": "R-SPO-5685230", "name": "CHEK1 phosphorylates RAD51", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747651" ], "products": [ "species_113582", "species_10747654" ], "modifiers": [ [ "species_10729605", "catalyst" ] ], "additional_components": [ "SPAC644.14c", "SPAC644.14c", "O13945", "SPAC23H4.02", "O74536", "SPCC74.03c" ] }, "reaction_10747710": { "compartment": "compartment_7660", "id": "reaction_10747710", "reactome": "R-SPO-5687464", "name": "MRN and RBBP8 resect DNA DSBs in MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747703" ], "products": [ "species_10747707", "species_30555" ], "modifiers": [ [ "species_10747703", "catalyst" ] ], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10733424": { "compartment": "compartment_7660", "id": "reaction_10733424", "reactome": "R-SPO-75998", "name": "Formation of RAD52 heptameric ring structure complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733420" ], "products": [ "species_10733422" ], "modifiers": [], "additional_components": [ "SPAC30D11.10", "P36592", "SPAC30D11.10" ] }, "reaction_10747593": { "compartment": "compartment_7660", "id": "reaction_10747593", "reactome": "R-SPO-5684140", "name": "ATM phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747581" ], "products": [ "species_113582", "species_10747590" ], "modifiers": [ [ "species_10747581", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747723": { "compartment": "compartment_7660", "id": "reaction_10747723", "reactome": "R-SPO-5687664", "name": "FEN1 cleaves displaced ssDNA flaps during MMEJ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747716" ], "products": [ "species_10747720", "species_10729528", "species_68454" ], "modifiers": [ [ "species_10747716", "catalyst" ] ], "additional_components": [ "P39750", "SPAC3G6.06c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "SPAC3G6.06c", "P39750", "SPAC3G6.06c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747676": { "compartment": "compartment_7660", "id": "reaction_10747676", "reactome": "R-SPO-5686430", "name": "MUS81 binds EME1, EME2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747661", "species_10747668" ], "products": [ "species_10747674" ], "modifiers": [], "additional_components": [ "SPAPB1E7.06c", "SPCC4G3.05c", "Q9C103", "SPAPB1E7.06c", "P87231", "SPCC4G3.05c" ] }, "reaction_10747584": { "compartment": "compartment_7660", "id": "reaction_10747584", "reactome": "R-SPO-5684096", "name": "CDK2 phosphorylates RBBP8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747575" ], "products": [ "species_113582", "species_10728937", "species_10747581" ], "modifiers": [ [ "species_10747575", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "P36630", "SPAPB2B4.03", "Q09683", "SPAC13C5.07", "P10815", "SPBC582.03", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "P36630", "SPAPB2B4.03", "Q09683", "SPAC13C5.07", "P10815", "SPBC582.03", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10756974": { "compartment": "compartment_70101", "id": "reaction_10756974", "reactome": "R-SPO-9018877", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9023708", "species_29356" ], "products": [ "species_9023712" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756059": { "compartment": "compartment_7660", "id": "reaction_10756059", "reactome": "R-SPO-8943007", "name": "SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756041", "species_10746403", "species_10733964", "species_10756047" ], "products": [ "species_10756049" ], "modifiers": [], "additional_components": [ "SPAC144.05", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9UTL9", "SPAC144.05", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10756057": { "compartment": "compartment_7660", "id": "reaction_10756057", "reactome": "R-SPO-8943003", "name": "SHPRH polyubiquitinates monoubiquitinated PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756049", "species_10756047" ], "products": [ "species_10756041", "species_10756054", "species_10746403", "species_10747373" ], "modifiers": [ [ "species_10756049", "catalyst" ] ], "additional_components": [ "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9UTL9", "SPAC144.05", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "SPAC144.05", "Q03392", "SPBC16D10.09", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9UTL9", "SPAC144.05", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10756390": { "compartment": "compartment_17947", "id": "reaction_10756390", "reactome": "R-SPO-8953946", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756378" ], "products": [ "species_10756387", "species_10741537" ], "modifiers": [ [ "species_10756378", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "O60065", "SPBC13G1.03c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O14136", "SPAC3C7.10", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH07", "SPAC1805.12c", "O60065", "SPBC13G1.03c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O14136", "SPAC3C7.10", "P0CH06", "SPAC11G7.04" ] }, "reaction_10756380": { "compartment": "compartment_17947", "id": "reaction_10756380", "reactome": "R-SPO-8953917", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756372", "species_10756376" ], "products": [ "species_10756378" ], "modifiers": [], "additional_components": [ "O60065", "SPBC13G1.03c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "O60065", "SPBC13G1.03c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O14136", "SPAC3C7.10", "P0CH06", "SPAC11G7.04" ] }, "reaction_10733705": { "compartment": "compartment_7660", "id": "reaction_10733705", "reactome": "R-SPO-109636", "name": "Recognition and Binding of Core Promoter Elements by TFIID", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109627", "species_10732699" ], "products": [ "species_10732998" ], "modifiers": [], "additional_components": [ "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c" ] }, "reaction_10733707": { "compartment": "compartment_7660", "id": "reaction_10733707", "reactome": "R-SPO-109637", "name": "Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732619", "species_10732998", "species_10732624" ], "products": [ "species_10733000" ], "modifiers": [], "additional_components": [ "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "SPAC16E8.16", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c" ] }, "reaction_10733709": { "compartment": "compartment_7660", "id": "reaction_10733709", "reactome": "R-SPO-109638", "name": "Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733000", "species_10730708" ], "products": [ "species_10733002" ], "modifiers": [], "additional_components": [ "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c" ] }, "reaction_10733006": { "compartment": "compartment_7660", "id": "reaction_10733006", "reactome": "R-SPO-75095", "name": "Binding of TFIIE to the growing preinitiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732711", "species_10733002" ], "products": [ "species_10733004" ], "modifiers": [], "additional_components": [ "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c" ] }, "reaction_10733711": { "compartment": "compartment_7660", "id": "reaction_10733711", "reactome": "R-SPO-109639", "name": "Formation of the closed pre-initiation complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733004", "species_10732494" ], "products": [ "species_10733340" ], "modifiers": [], "additional_components": [ "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750331": { "compartment": "compartment_5460", "id": "reaction_10750331", "reactome": "R-SPO-6783939", "name": "PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10750328", "catalyst" ] ], "additional_components": [ "Q9P7Y7", "SPAPYUG7.05" ] }, "reaction_10729991": { "compartment": "compartment_70101", "id": "reaction_10729991", "reactome": "R-SPO-70606", "name": "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_31633" ], "products": [ "species_29370", "species_29472", "species_29372" ], "modifiers": [ [ "species_10729988", "catalyst" ] ], "additional_components": [ "Q09179", "SPAC23H4.06" ] }, "reaction_10730012": { "compartment": "compartment_5460", "id": "reaction_10730012", "reactome": "R-SPO-70654", "name": "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113585" ], "products": [ "species_31339", "species_113552" ], "modifiers": [ [ "species_10730009", "catalyst" ] ], "additional_components": [ "Q9P7L5", "SPBC21C3.08c" ] }, "reaction_10729993": { "compartment": "compartment_5460", "id": "reaction_10729993", "reactome": "R-SPO-70613", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113587" ], "products": [ "species_113594", "species_113553" ], "modifiers": [ [ "species_10729968", "catalyst" ] ], "additional_components": [ "O94320", "SPBC725.01" ] }, "reaction_10730022": { "compartment": "compartment_5460", "id": "reaction_10730022", "reactome": "R-SPO-70664", "name": "PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113529", "species_113590" ], "products": [ "species_379717", "species_113526" ], "modifiers": [ [ "species_10730019", "catalyst" ] ], "additional_components": [ "Q9P7Y7", "SPAPYUG7.05" ] }, "reaction_10740180": { "compartment": "compartment_5460", "id": "reaction_10740180", "reactome": "R-SPO-508040", "name": "glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_113552", "species_113529", "species_113593" ], "products": [ "species_31339", "species_113548", "species_113563", "species_113581" ], "modifiers": [ [ "species_10740177", "catalyst" ] ], "additional_components": [ "Q9UT44", "SPAC821.11" ] }, "reaction_10740380": { "compartment": "compartment_70101", "id": "reaction_10740380", "reactome": "R-SPO-893616", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29398" ], "products": [ "species_893598", "species_29432" ], "modifiers": [ [ "species_10740371", "catalyst" ] ], "additional_components": [ "O14209", "SPAC6B12.04c" ] }, "reaction_10750338": { "compartment": "compartment_70101", "id": "reaction_10750338", "reactome": "R-SPO-6783955", "name": "PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_35305" ], "products": [ "species_29366", "species_113538" ], "modifiers": [ [ "species_10750335", "catalyst" ] ], "additional_components": [ "Q9P7Y7", "SPAPYUG7.05" ] }, "reaction_10734483": { "compartment": "compartment_17906", "id": "reaction_10734483", "reactome": "R-SPO-114284", "name": "Release of Cytochrome c from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734481" ], "products": [ "species_10734479" ], "modifiers": [], "additional_components": [ "SPCC191.07", "SPCC191.07" ] }, "reaction_10752635": { "compartment": "compartment_984", "id": "reaction_10752635", "reactome": "R-SPO-6805981", "name": "HMGB1 release from cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737741" ], "products": [ "species_10752522" ], "modifiers": [], "additional_components": [ "SPAC57A10.09c", "SPAC57A10.09c" ] }, "reaction_10745096": { "compartment": "compartment_7660", "id": "reaction_10745096", "reactome": "R-SPO-5082384", "name": "HSP70:DNAJB1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744254", "species_10744224" ], "products": [ "species_10744256" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O59855", "SPCC1739.13", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06" ] }, "reaction_10744320": { "compartment": "compartment_7660", "id": "reaction_10744320", "reactome": "R-SPO-3371582", "name": "HSBP1 binds HSF1 trimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744252", "species_10744316" ], "products": [ "species_10744318" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14330", "SPBC16E9.15", "O14330", "SPBC16E9.15", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10757482": { "compartment": "compartment_70101", "id": "reaction_10757482", "reactome": "R-SPO-9635743", "name": "PTPN7 binds p-T,Y-MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757459", "species_10744304" ], "products": [ "species_10757461" ], "modifiers": [], "additional_components": [ "P27574", "SPAC26F1.10c", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01" ] }, "reaction_10746868": { "compartment": "compartment_70101", "id": "reaction_10746868", "reactome": "R-SPO-5674496", "name": "Activated MAPKs phosphorylate MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746838", "species_113592" ], "products": [ "species_29370", "species_10746865" ], "modifiers": [ [ "species_10746855", "catalyst" ] ], "additional_components": [ "P10506", "SPAC1D4.13", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10746885": { "compartment": "compartment_7660", "id": "reaction_10746885", "reactome": "R-SPO-5675373", "name": "Nuclear DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746859", "species_29356" ], "products": [ "species_10746870", "species_113550" ], "modifiers": [ [ "species_10746872", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPBC1685.01" ] }, "reaction_10757480": { "compartment": "compartment_70101", "id": "reaction_10757480", "reactome": "R-SPO-9635739", "name": "PTPN7 dephosphorylates p-T,Y-MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757461", "species_29356" ], "products": [ "species_10757477", "species_29372" ], "modifiers": [ [ "species_10757461", "catalyst" ] ], "additional_components": [ "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01", "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01", "P27574", "SPAC26F1.10c", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P32587", "SPAC11E3.09", "P32586", "SPAC19D5.01" ] }, "reaction_10746906": { "compartment": "compartment_70101", "id": "reaction_10746906", "reactome": "R-SPO-5675376", "name": "Cytosolic DUSPs dephosphorylate MAPKs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10746855" ], "products": [ "species_10746891", "species_29372" ], "modifiers": [ [ "species_10746893", "catalyst" ] ], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPBC1685.01" ] }, "reaction_10745486": { "compartment": "compartment_7660", "id": "reaction_10745486", "reactome": "R-SPO-5228523", "name": "RANBP2 SUMOylates MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743716", "species_10743647" ], "products": [ "species_10743639", "species_10743724" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPCC285.17", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "O74503", "SPCC285.17", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10743731": { "compartment": "compartment_7660", "id": "reaction_10743731", "reactome": "R-SPO-3000434", "name": "PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743716", "species_10743647" ], "products": [ "species_10743639", "species_10743724" ], "modifiers": [ [ "species_10743726", "catalyst" ] ], "additional_components": [ "SPCC285.17", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "O74503", "SPCC285.17", "SPAC1687.05" ] }, "reaction_10751267": { "compartment": "compartment_876", "id": "reaction_10751267", "reactome": "R-SPO-6797630", "name": "LRPP4(LRPP1-3,5) hydrolyse LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_417891", "species_109276" ], "products": [ "species_6797635", "species_109277" ], "modifiers": [ [ "species_10751264", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10757778": { "compartment": "compartment_70101", "id": "reaction_10757778", "reactome": "R-SPO-9668419", "name": "SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738115", "species_113592", "species_29356" ], "products": [ "species_10738111", "species_29370", "species_29372" ], "modifiers": [ [ "species_10757769", "catalyst" ] ], "additional_components": [ "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c" ] }, "reaction_10743751": { "compartment": "compartment_13231", "id": "reaction_10743751", "reactome": "R-SPO-3000449", "name": "UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743738", "species_10743647" ], "products": [ "species_10743639", "species_10743748" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "P41391", "SPAC22E12.07", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P41391", "SPAC22E12.07", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10757349": { "compartment": "compartment_1598585", "id": "reaction_10757349", "reactome": "R-SPO-9624845", "name": "RCC1 stimulates GDP to GTP exchange on RAN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737260", "species_29438" ], "products": [ "species_10745968", "species_29420" ], "modifiers": [ [ "species_10757346", "catalyst" ] ], "additional_components": [ "species_29420", "P28748", "SPBC1289.03c", "P28748", "SPBC1289.03c", "species_29438", "SPBC557.03c" ] }, "reaction_10757341": { "compartment": "compartment_13231", "id": "reaction_10757341", "reactome": "R-SPO-9624798", "name": "LBR binds KPNB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737539", "species_10757337" ], "products": [ "species_10757339" ], "modifiers": [], "additional_components": [ "SPAC1B1.03c", "SPBC16G5.18", "Q09195", "SPBC16G5.18", "O13864", "SPAC1B1.03c" ] }, "reaction_10757773": { "compartment": "compartment_70101", "id": "reaction_10757773", "reactome": "R-SPO-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757769", "species_10740625" ], "products": [ "species_10757771" ], "modifiers": [], "additional_components": [ "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "SPAC2G11.06", "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "Q09803", "SPAC2G11.06", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c" ] }, "reaction_10743193": { "compartment": "compartment_70101", "id": "reaction_10743193", "reactome": "R-SPO-2467775", "name": "Autocleavage of ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743182" ], "products": [ "species_10743190" ], "modifiers": [ [ "species_10743182", "catalyst" ] ], "additional_components": [ "SPCC5E4.04", "P18296", "SPCC5E4.04", "SPCC5E4.04" ] }, "reaction_10757442": { "compartment": "compartment_70101", "id": "reaction_10757442", "reactome": "R-SPO-9634169", "name": "POM121 and NDC1 bind the Nup93 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757438", "species_10757311", "species_10733090", "species_10757436" ], "products": [ "species_10757440" ], "modifiers": [], "additional_components": [ "SPAP27G11.10c", "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "Q09904", "SPAC30D11.04c", "O36030", "SPAC4F10.18", "Q10331", "SPBC428.01c", "Q9UTK4", "SPAC1486.05", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "Q9UUE5", "SPBC17G9.04c", "O43044", "SPBC3B9.16c", "SPAC1786.03", "O94418", "SPCC1620.11", "O13838", "SPAC19E9.01c", "P78847", "SPCC290.03c", "Q9URX8", "SPAC890.06", "O94418", "SPCC1620.11", "Q09904", "SPAC30D11.04c", "Q10331", "SPBC428.01c", "P78847", "SPCC290.03c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q9UUE5", "SPBC17G9.04c", "Q9P7M8", "SPAP27G11.10c", "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "O13961", "SPAC1786.03", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "O43044", "SPBC3B9.16c" ] }, "reaction_10757353": { "compartment": "compartment_70101", "id": "reaction_10757353", "reactome": "R-SPO-9624876", "name": "RAN:GTP recruits nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9624879", "species_10745968" ], "products": [ "species_10757351" ], "modifiers": [], "additional_components": [ "P28748", "SPBC1289.03c", "species_29438", "P28748", "SPBC1289.03c", "species_29438" ] }, "reaction_10743226": { "compartment": "compartment_70101", "id": "reaction_10743226", "reactome": "R-SPO-2467798", "name": "PTTG1 (Securin) sequesters ESPL1 (Separase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743182", "species_10743222" ], "products": [ "species_10743224" ], "modifiers": [], "additional_components": [ "SPCC5E4.04", "SPBC14C8.01c", "P18296", "SPCC5E4.04", "P21135", "SPBC14C8.01c" ] }, "reaction_10757356": { "compartment": "compartment_70101", "id": "reaction_10757356", "reactome": "R-SPO-9624893", "name": "RAN stimulates fusion of nuclear envelope (NE) membranes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757351", "species_29356" ], "products": [ "species_10737260", "species_29372", "species_9624890" ], "modifiers": [ [ "species_10743748", "catalyst" ] ], "additional_components": [ "P28748", "SPBC1289.03c", "species_29438", "species_29420", "P28748", "SPBC1289.03c", "O13351", "SPBC365.06", "P41391", "SPAC22E12.07" ] }, "reaction_10757775": { "compartment": "compartment_70101", "id": "reaction_10757775", "reactome": "R-SPO-9668405", "name": "SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757757", "species_10757767" ], "products": [ "species_10757769" ], "modifiers": [], "additional_components": [ "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "Q9P3U2", "SPAC328.04", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O74490", "SPCC1442.17c", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c" ] }, "reaction_10757313": { "compartment": "compartment_70101", "id": "reaction_10757313", "reactome": "R-SPO-9618378", "name": "POM121 binds the Nup107-Nup160 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757309", "species_10733083" ], "products": [ "species_10757311" ], "modifiers": [], "additional_components": [ "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "O36030", "SPAC4F10.18", "Q10331", "SPBC428.01c", "Q9UTK4", "SPAC1486.05", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "Q9UUE5", "SPBC17G9.04c", "O43044", "SPBC3B9.16c", "SPAC30D11.04c", "Q10099", "SPAC15F9.02", "O13856", "SPAC1A6.02", "Q09904", "SPAC30D11.04c", "O36030", "SPAC4F10.18", "Q10331", "SPBC428.01c", "Q9UTK4", "SPAC1486.05", "Q9UTH0", "SPAC1805.04", "O94319", "SPBC215.15", "Q9UUE5", "SPBC17G9.04c", "O43044", "SPBC3B9.16c" ] }, "reaction_10758064": { "compartment": "compartment_70101", "id": "reaction_10758064", "reactome": "R-SPO-9748957", "name": "GMPS dimer transforms 6TXMP to 6TGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_29356", "species_9748959" ], "products": [ "species_70106", "species_9748970", "species_29404", "species_111294", "species_76577" ], "modifiers": [ [ "species_10758061", "catalyst" ] ], "additional_components": [ "Q9P772", "SPBC2F12.14c" ] }, "reaction_10758081": { "compartment": "compartment_70101", "id": "reaction_10758081", "reactome": "R-SPO-9750546", "name": "ABCC4 transports TPMP substrates from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750587", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750548", "species_29372" ], "modifiers": [ [ "species_10741716", "catalyst" ] ], "additional_components": [ "species_9748992", "species_9748970", "pubchem.compound:3037883", "CHEBI:80613", "pubchem.compound:3037883", "CHEBI:2332", "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10758059": { "compartment": "compartment_70101", "id": "reaction_10758059", "reactome": "R-SPO-9748949", "name": "GUK1 phosphorylates 6TGMP to 6TGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748970", "species_113592" ], "products": [ "species_29370", "species_9748960" ], "modifiers": [ [ "species_10732507", "catalyst" ] ], "additional_components": [ "SPBC1198.05" ] }, "reaction_10758057": { "compartment": "compartment_70101", "id": "reaction_10758057", "reactome": "R-SPO-9748945", "name": "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9748992", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_9748959" ], "modifiers": [ [ "species_10732525", "catalyst" ] ], "additional_components": [ "O14344", "SPBC2F12.14c" ] }, "reaction_10758087": { "compartment": "compartment_70101", "id": "reaction_10758087", "reactome": "R-SPO-9753278", "name": "ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10741710", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "CHEBI:132962", "CHEBI:32636", "CHEBI:32635", "Q10185", "SPAC3F10.11c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10758096": { "compartment": "compartment_70101", "id": "reaction_10758096", "reactome": "R-SPO-9753632", "name": "CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753680", "species_29356" ], "products": [ "species_9753653", "species_29424" ], "modifiers": [ [ "species_10741586", "catalyst" ] ], "additional_components": [ "Q9P6I2", "SPBC1198.08", "species_113527" ] }, "reaction_10758070": { "compartment": "compartment_70101", "id": "reaction_10758070", "reactome": "R-SPO-9748999", "name": "NME1:2 hexamer phosphorylates 6TGDP to 6TGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9748960" ], "products": [ "species_29370", "species_9748947" ], "modifiers": [ [ "species_10740061", "catalyst" ] ], "additional_components": [ "P49740", "SPAC806.07" ] }, "reaction_10758089": { "compartment": "compartment_70101", "id": "reaction_10758089", "reactome": "R-SPO-9753283", "name": "ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_9753559" ], "products": [ "species_29370", "species_9753562", "species_29372" ], "modifiers": [ [ "species_10741716", "catalyst" ] ], "additional_components": [ "CHEBI:32635", "CHEBI:132962", "CHEBI:32636", "CHEBI:32635", "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10758068": { "compartment": "compartment_70101", "id": "reaction_10758068", "reactome": "R-SPO-9748969", "name": "NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9749033" ], "products": [ "species_29370", "species_9749032" ], "modifiers": [ [ "species_10740061", "catalyst" ] ], "additional_components": [ "P49740", "SPAC806.07" ] }, "reaction_10758084": { "compartment": "compartment_70101", "id": "reaction_10758084", "reactome": "R-SPO-9750656", "name": "ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9750692", "species_113592", "species_29356" ], "products": [ "species_29370", "species_9750678", "species_29372" ], "modifiers": [ [ "species_10741710", "catalyst" ] ], "additional_components": [ "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "CHEBI:176960", "CHEBI:9008", "CHEBI:58044", "CHEBI:88742", "CHEBI:176976", "CHEBI:36654", "CHEBI:176960", "Q10185", "SPAC3F10.11c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10742965": { "compartment": "compartment_70101", "id": "reaction_10742965", "reactome": "R-SPO-2162078", "name": "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2161185", "species_29360" ], "products": [ "species_70106", "species_73473", "species_2162081" ], "modifiers": [ [ "species_10730504", "catalyst" ] ], "additional_components": [ "species_442320", "P78870", "SPCC13B11.04c", "O74540", "SPCC13B11.04c" ] }, "reaction_10758066": { "compartment": "compartment_70101", "id": "reaction_10758066", "reactome": "R-SPO-9748963", "name": "GUK1 phosphorylates 6TdGMP to 6TdGDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9749031", "species_113592" ], "products": [ "species_29370", "species_9749033" ], "modifiers": [ [ "species_10732507", "catalyst" ] ], "additional_components": [ "SPBC1198.05" ] }, "reaction_10758098": { "compartment": "compartment_876", "id": "reaction_10758098", "reactome": "R-SPO-9753634", "name": "GGT dimers hydrolyse APAP-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9753685", "species_29356" ], "products": [ "species_9753680", "species_29404" ], "modifiers": [ [ "species_10745932", "catalyst" ] ], "additional_components": [ "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10758094": { "compartment": "compartment_70101", "id": "reaction_10758094", "reactome": "R-SPO-9753284", "name": "ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_9753629", "species_29356" ], "products": [ "species_29370", "species_9753624", "species_29372" ], "modifiers": [ [ "species_10758091", "catalyst" ] ], "additional_components": [ "CHEBI:133438", "species_9753653", "CHEBI:133066", "CHEBI:133435", "Q92337", "SPAC9E9.12c", "Q10185", "SPAC3F10.11c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10735847": { "compartment": "compartment_5460", "id": "reaction_10735847", "reactome": "R-SPO-188467", "name": "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_188458" ], "products": [ "species_188451", "species_31649" ], "modifiers": [ [ "species_10735844", "catalyst" ] ], "additional_components": [ "SPCC1223.03c" ] }, "reaction_10738355": { "compartment": "compartment_70101", "id": "reaction_10738355", "reactome": "R-SPO-389788", "name": "Activation of PAKs by RAC1 and CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738349", "species_10738231" ], "products": [ "species_10738353", "species_10738351" ], "modifiers": [], "additional_components": [ "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c" ] }, "reaction_10741676": { "compartment": "compartment_70101", "id": "reaction_10741676", "reactome": "R-SPO-1358791", "name": "Phosphorylation of USP8 by P-AKT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741666" ], "products": [ "species_29370", "species_10741674" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "O60079", "SPCC1494.05c", "Q9USM5", "SPCC16A11.12c", "O60079", "SPCC1494.05c", "Q9USM5", "SPCC16A11.12c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10757404": { "compartment": "compartment_70101", "id": "reaction_10757404", "reactome": "R-SPO-9627369", "name": "SEPT4 binds XIAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757400", "species_10745678" ], "products": [ "species_10757402" ], "modifiers": [], "additional_components": [ "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11", "SPCC962.02c", "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "O14064", "SPCC962.02c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11" ] }, "reaction_10732312": { "compartment": "compartment_70101", "id": "reaction_10732312", "reactome": "R-SPO-73580", "name": "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_73578" ], "products": [ "species_73566", "species_76577" ], "modifiers": [ [ "species_10732309", "catalyst" ] ], "additional_components": [ "O94413", "SPCC1620.06c", "P41831", "SPCC1620.06c", "P87171", "SPCC1620.06c" ] }, "reaction_10735815": { "compartment": "compartment_70101", "id": "reaction_10735815", "reactome": "R-SPO-177784", "name": "ribose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10730283", "catalyst" ] ], "additional_components": [ "SPAC144.12" ] }, "reaction_10730278": { "compartment": "compartment_70101", "id": "reaction_10730278", "reactome": "R-SPO-71303", "name": "RPE dimers isomerise RU5P to XY5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29732" ], "products": [ "species_29790" ], "modifiers": [ [ "species_10730275", "catalyst" ] ], "additional_components": [ "O14105", "SPAC31G5.05c", "species_113531" ] }, "reaction_10750445": { "compartment": "compartment_70101", "id": "reaction_10750445", "reactome": "R-SPO-6787329", "name": "PGM2:Mg2+ isomerises R1P to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_112016" ], "products": [ "species_73578" ], "modifiers": [ [ "species_10729638", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10734989": { "compartment": "compartment_70101", "id": "reaction_10734989", "reactome": "R-SPO-163764", "name": "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29878", "species_29512" ], "products": [ "species_29578", "species_29882" ], "modifiers": [ [ "species_10730293", "catalyst" ] ], "additional_components": [ "O42700", "SPCC1020.06c" ] }, "reaction_10736696": { "compartment": "compartment_70101", "id": "reaction_10736696", "reactome": "R-SPO-199803", "name": "xylulose 5-phosphate <=> D-ribulose 5-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29790" ], "products": [ "species_29732" ], "modifiers": [ [ "species_10730275", "catalyst" ] ], "additional_components": [ "O14105", "SPAC31G5.05c", "species_113531" ] }, "reaction_10730248": { "compartment": "compartment_70101", "id": "reaction_10730248", "reactome": "R-SPO-71296", "name": "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31467", "species_29356" ], "products": [ "species_29996" ], "modifiers": [ [ "species_10730245", "catalyst" ] ], "additional_components": [ "SPCC16C4.10" ] }, "reaction_10730258": { "compartment": "compartment_70101", "id": "reaction_10730258", "reactome": "R-SPO-71299", "name": "6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_29996" ], "products": [ "species_70106", "species_29732", "species_29364", "species_113528" ], "modifiers": [ [ "species_10730255", "catalyst" ] ], "additional_components": [ "P78812", "SPBC660.16" ] }, "reaction_10729691": { "compartment": "compartment_70101", "id": "reaction_10729691", "reactome": "R-SPO-70377", "name": "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_30537" ], "products": [ "species_70106", "species_29364", "species_31467" ], "modifiers": [ [ "species_10729688", "catalyst" ] ], "additional_components": [ "species_29366", "O00091", "SPAC3A12.18" ] }, "reaction_10756527": { "compartment": "compartment_70101", "id": "reaction_10756527", "reactome": "R-SPO-8982667", "name": "PGM2:Mg2+ isomerises dR1P to dR5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787326" ], "products": [ "species_6787328" ], "modifiers": [ [ "species_10729638", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10756433": { "compartment": "compartment_70101", "id": "reaction_10756433", "reactome": "R-SPO-8955844", "name": "RBKS phosphorylates ribose to R5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8955853" ], "products": [ "species_29370", "species_73578" ], "modifiers": [ [ "species_10756430", "catalyst" ] ], "additional_components": [ "SPBC16G5.02c" ] }, "reaction_10734063": { "compartment": "compartment_70101", "id": "reaction_10734063", "reactome": "R-SPO-111215", "name": "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73578", "species_110644" ], "products": [ "species_73566", "species_109386" ], "modifiers": [ [ "species_10732305", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_29372", "catalyst" ] ], "additional_components": [ "O94413", "SPCC1620.06c", "P41831", "SPCC1620.06c", "P87171", "SPCC1620.06c" ] }, "reaction_10743558": { "compartment": "compartment_70101", "id": "reaction_10743558", "reactome": "R-SPO-2730872", "name": "Activation of Calcineurin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742830", "species_74016", "species_10737034" ], "products": [ "species_10743532" ], "modifiers": [], "additional_components": [ "species_442320", "Q9UU93", "SPCC830.06", "Q12705", "SPBP4H10.04", "CHEBI:29034", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q12705", "SPBP4H10.04", "CHEBI:29034" ] }, "reaction_10744811": { "compartment": "compartment_70101", "id": "reaction_10744811", "reactome": "R-SPO-4551465", "name": "Translocation of NFATC1:CaN:CaM to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744805" ], "products": [ "species_10744809" ], "modifiers": [], "additional_components": [ "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q12705", "SPBP4H10.04", "CHEBI:29034", "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "Q12705", "SPBP4H10.04", "O14008", "SPAC29A4.05", "CHEBI:29034" ] }, "reaction_10743992": { "compartment": "compartment_20699", "id": "reaction_10743992", "reactome": "R-SPO-3247836", "name": "Retromer recycles WLS to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743986" ], "products": [ "species_10743990" ], "modifiers": [], "additional_components": [ "Q9UTI5", "SPAC15E1.06", "O74552", "SPCC777.13", "O94291", "SPBC887.06c", "Q10243", "SPAC4G9.13c", "Q9UTI5", "SPAC15E1.06", "O74552", "SPCC777.13", "O94291", "SPBC887.06c", "Q10243", "SPAC4G9.13c" ] }, "reaction_10750278": { "compartment": "compartment_7660", "id": "reaction_10750278", "reactome": "R-SPO-6782211", "name": "DNA polymerases delta, epsilon or kappa bind the TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749283", "species_10749285", "species_10750264", "species_10729448" ], "products": [ "species_10750276" ], "modifiers": [], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "O74944", "SPCC553.07c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P36617", "SPCC970.01", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "P87324", "SPAC27E2.05", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P36617", "SPCC970.01", "P87123", "SPAC3A12.07", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94508", "SPBC646.02", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750246": { "compartment": "compartment_7660", "id": "reaction_10750246", "reactome": "R-SPO-6782131", "name": "ERCC2-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10750232" ], "products": [ "species_113582", "species_10750243", "species_113550" ], "modifiers": [ [ "species_10750232", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750267": { "compartment": "compartment_7660", "id": "reaction_10750267", "reactome": "R-SPO-6782204", "name": "5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750260" ], "products": [ "species_10750264" ], "modifiers": [ [ "species_10750260", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P36617", "SPCC970.01", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P36617", "SPCC970.01", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P36617", "SPCC970.01", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750258": { "compartment": "compartment_7660", "id": "reaction_10750258", "reactome": "R-SPO-6782138", "name": "ERCC5 and RPA bind TC-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747765", "species_10750254", "species_10729504" ], "products": [ "species_10750256" ], "modifiers": [], "additional_components": [ "SPBC3E7.08c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750262": { "compartment": "compartment_7660", "id": "reaction_10750262", "reactome": "R-SPO-6782141", "name": "Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750256", "species_10733829" ], "products": [ "species_10750260" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P36617", "SPCC970.01", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "Q92374", "SPCC23B6.05c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "P28706", "SPBC3E7.08c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10757829": { "compartment": "compartment_7660", "id": "reaction_10757829", "reactome": "R-SPO-9684118", "name": "ERCC3-facilitated RNA Pol II backtracking in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10750243" ], "products": [ "species_113582", "species_10750254", "species_113550" ], "modifiers": [ [ "species_10750243", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "O59753", "SPBC649.03", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "Q9Y7V2", "SPCC645.13", "O14011", "SPAC29A4.08c", "O74366", "SPBC30B4.07c" ] }, "reaction_10750281": { "compartment": "compartment_7660", "id": "reaction_10750281", "reactome": "R-SPO-6782224", "name": "3' incision by ERCC5 (XPG) in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750276" ], "products": [ "species_10750269", "species_10747765", "species_10747770", "species_10733829" ], "modifiers": [ [ "species_10750276", "catalyst" ] ], "additional_components": [ "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "P87324", "SPAC27E2.05", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P36617", "SPCC970.01", "P87123", "SPAC3A12.07", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94508", "SPBC646.02", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "SPBC3E7.08c", "SPBC649.03", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "P49373", "SPAC20H4.03c", "Q92373", "SPCC1753.01c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "O74825", "SPBC337.14", "Q06182", "SPBC4F6.15c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "P87324", "SPAC27E2.05", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P36617", "SPCC970.01", "P87123", "SPAC3A12.07", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94508", "SPBC646.02", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "P28706", "SPBC3E7.08c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c" ] }, "reaction_10740162": { "compartment": "compartment_876", "id": "reaction_10740162", "reactome": "R-SPO-507873", "name": "Aquaporins passively transport urea out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29514" ], "products": [ "species_432019" ], "modifiers": [ [ "species_10740159", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10739398": { "compartment": "compartment_876", "id": "reaction_10739398", "reactome": "R-SPO-444160", "name": "VMAT1/2 can mediate the transport of biogenic amines", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_444154" ], "products": [ "species_444152" ], "modifiers": [ [ "species_10739395", "catalyst" ] ], "additional_components": [ "CHEBI:18295", "species_351601", "CHEBI:18357", "CHEBI:28918", "species_209914", "CHEBI:18295", "species_351601", "CHEBI:18357", "CHEBI:28918", "species_209914", "O74852", "SPCC18.02" ] }, "reaction_10739315": { "compartment": "compartment_876", "id": "reaction_10739315", "reactome": "R-SPO-434650", "name": "MATEs mediate extrusion of xenobiotics", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_446589", "species_351626" ], "products": [ "species_70106", "species_446597" ], "modifiers": [ [ "species_10739312", "catalyst" ] ], "additional_components": [ "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "CHEBI:8428", "CHEBI:46020", "CHEBI:42820", "CHEBI:16737", "LigandDisplayForward?ligandId=1231", "CHEBI:641", "CHEBI:6801", "Q9USK3", "SPCC4B3.13", "Q10085", "SPCC4B3.13", "Q9UT92", "SPCC4B3.13" ] }, "reaction_10740155": { "compartment": "compartment_876", "id": "reaction_10740155", "reactome": "R-SPO-507870", "name": "Aquaporins passively transport water out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10756479": { "compartment": "compartment_70101", "id": "reaction_10756479", "reactome": "R-SPO-8959798", "name": "SLC30A10 transports Mn2+ from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29418" ], "products": [ "species_266099" ], "modifiers": [ [ "species_10756476", "catalyst" ] ], "additional_components": [ "SPAC23C11.14" ] }, "reaction_10740289": { "compartment": "compartment_20699", "id": "reaction_10740289", "reactome": "R-SPO-742345", "name": "SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742368" ], "products": [ "species_205683" ], "modifiers": [ [ "species_10740286", "catalyst" ] ], "additional_components": [ "SPAC22F8.04" ] }, "reaction_10739323": { "compartment": "compartment_876", "id": "reaction_10739323", "reactome": "R-SPO-435366", "name": "ZnT1 mediates the efflux of zinc from the cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_158417" ], "modifiers": [ [ "species_10739320", "catalyst" ] ], "additional_components": [ "SPAC23C11.14" ] }, "reaction_10740865": { "compartment": "compartment_876", "id": "reaction_10740865", "reactome": "R-SPO-939763", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_947594", "species_113592", "species_29356" ], "products": [ "species_29370", "species_947588", "species_29372" ], "modifiers": [ [ "species_10740862", "catalyst" ] ], "additional_components": [ "species_1500646", "species_1500581", "species_1500646", "species_1500581", "Q10309", "SPAC6C3.06c", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O94296", "SPBC887.12", "Q09891", "SPAC24B11.12c" ] }, "reaction_10740157": { "compartment": "compartment_876", "id": "reaction_10740157", "reactome": "R-SPO-507871", "name": "Aquaporins passively transport glycerol out of cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10747160": { "compartment": "compartment_70101", "id": "reaction_10747160", "reactome": "R-SPO-5678863", "name": "CFTR transports Cl- from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_352022", "species_29356" ], "products": [ "species_29370", "species_188972", "species_29372" ], "modifiers": [ [ "species_10738217", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10745661": { "compartment": "compartment_70101", "id": "reaction_10745661", "reactome": "R-SPO-5336466", "name": "MRS2 transports Mg2+ from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29926" ], "products": [ "species_109496" ], "modifiers": [ [ "species_10745658", "catalyst" ] ], "additional_components": [ "SPBC25H2.08c" ] }, "reaction_10745601": { "compartment": "compartment_70101", "id": "reaction_10745601", "reactome": "R-SPO-5251989", "name": "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5252122" ], "products": [ "species_29370", "species_5252016", "species_29372" ], "modifiers": [ [ "species_10745598", "catalyst" ] ], "additional_components": [ "O74431", "SPCC1672.11c", "O14022", "SPAC29A4.19c" ] }, "reaction_10739257": { "compartment": "compartment_876", "id": "reaction_10739257", "reactome": "R-SPO-432049", "name": "Aquaporin-9 passively transports glycerol into cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10739254", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10740300": { "compartment": "compartment_20699", "id": "reaction_10740300", "reactome": "R-SPO-742373", "name": "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_742353" ], "products": [ "species_742361" ], "modifiers": [ [ "species_10740294", "catalyst" ] ], "additional_components": [ "SPBC1734.09" ] }, "reaction_10740787": { "compartment": "compartment_20699", "id": "reaction_10740787", "reactome": "R-SPO-936883", "name": "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_113592", "species_29356" ], "products": [ "species_29370", "species_167012", "species_29372" ], "modifiers": [ [ "species_10740784", "catalyst" ] ], "additional_components": [ "O59868", "SPBC31E1.02c", "species_29926" ] }, "reaction_10739115": { "compartment": "compartment_876", "id": "reaction_10739115", "reactome": "R-SPO-429101", "name": "HMIT co-transports myo-inositol with a proton", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429130", "species_351626" ], "products": [ "species_70106", "species_426910" ], "modifiers": [ [ "species_10739112", "catalyst" ] ], "additional_components": [ "SPAC4F8.15" ] }, "reaction_10739331": { "compartment": "compartment_1462052", "id": "reaction_10739331", "reactome": "R-SPO-437085", "name": "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29426" ], "products": [ "species_216785" ], "modifiers": [ [ "species_10739328", "catalyst" ] ], "additional_components": [ "SPAC17D4.03c" ] }, "reaction_10740662": { "compartment": "compartment_74700", "id": "reaction_10740662", "reactome": "R-SPO-917841", "name": "Acidification of Tf:TfR1 containing endosome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_113592", "species_29356" ], "products": [ "species_29370", "species_74722", "species_29372" ], "modifiers": [ [ "species_10732848", "catalyst" ] ], "additional_components": [ "P50515", "SPAC1B3.14", "O43046", "SPBC3B9.18c", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O59823", "SPCC965.03", "O14046", "SPAC2C4.13", "O13742", "SPAC16E8.07c", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q69Z14", "SPBC1685.16", "Q9HDW6", "SPAPB2B4.05" ] }, "reaction_10749527": { "compartment": "compartment_70101", "id": "reaction_10749527", "reactome": "R-SPO-5692480", "name": "ATP13A2 transports cations from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_5692450" ], "products": [ "species_29370", "species_29372", "species_5692484" ], "modifiers": [ [ "species_10749524", "catalyst" ] ], "additional_components": [ "O74431", "SPCC1672.11c", "O14022", "SPAC29A4.19c" ] }, "reaction_10754737": { "compartment": "compartment_70101", "id": "reaction_10754737", "reactome": "R-SPO-8866553", "name": "misfolded CFTR is degraded by the 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754735" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9P7V2", "SPAC30.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10740153": { "compartment": "compartment_876", "id": "reaction_10740153", "reactome": "R-SPO-507869", "name": "Aquaporins passively transport glycerol into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_192438" ], "products": [ "species_76116" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10755496": { "compartment": "compartment_70101", "id": "reaction_10755496", "reactome": "R-SPO-8875902", "name": "SLC45A3 transports Glc from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70115" ], "products": [ "species_70113" ], "modifiers": [ [ "species_10755493", "catalyst" ] ], "additional_components": [ "SPAC2F3.08" ] }, "reaction_10745471": { "compartment": "compartment_70101", "id": "reaction_10745471", "reactome": "R-SPO-5223317", "name": "ABCB9 transports peptides from cytosol to lysosomal lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5223341", "species_113592", "species_29356" ], "products": [ "species_29370", "species_29372", "species_5223344" ], "modifiers": [ [ "species_10745468", "catalyst" ] ], "additional_components": [ "P78966", "SPBC25B2.02c" ] }, "reaction_10745674": { "compartment": "compartment_70101", "id": "reaction_10745674", "reactome": "R-SPO-5339538", "name": "MAGT1 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10745671", "catalyst" ] ], "additional_components": [ "SPAPB17E12.11" ] }, "reaction_10738200": { "compartment": "compartment_70616", "id": "reaction_10738200", "reactome": "R-SPO-382560", "name": "ABC7, mABC1 and mABC2 mediate heme transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_189444", "species_113593" ], "products": [ "species_113548", "species_113581", "species_71185" ], "modifiers": [ [ "species_10738197", "catalyst" ] ], "additional_components": [ "Q02592", "SPCC737.09c", "O14286", "SPAC15A10.01", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10739371": { "compartment": "compartment_12045", "id": "reaction_10739371", "reactome": "R-SPO-442393", "name": "ZIP7 mediates zinc efflux from the endoplasmic reticulum", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_442320" ], "products": [ "species_29426" ], "modifiers": [ [ "species_10739368", "catalyst" ] ], "additional_components": [ "SPAP8A3.03" ] }, "reaction_10743495": { "compartment": "compartment_70101", "id": "reaction_10743495", "reactome": "R-SPO-2684901", "name": "ANOs transport cytosolic Cl- to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_352022" ], "products": [ "species_188972" ], "modifiers": [ [ "species_10743492", "catalyst" ], [ "species_74016", "catalyst" ] ], "additional_components": [ "O13621", "SPBC691.05c" ] }, "reaction_10739417": { "compartment": "compartment_876", "id": "reaction_10739417", "reactome": "R-SPO-445714", "name": "Aquaporin-3 passively transports water out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356" ], "products": [ "species_109276" ], "modifiers": [ [ "species_10739414", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10740665": { "compartment": "compartment_876", "id": "reaction_10740665", "reactome": "R-SPO-917870", "name": "SLC46A1 transports hemes from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9707310" ], "products": [ "species_9707308" ], "modifiers": [ [ "species_10736861", "catalyst" ] ], "additional_components": [ "species_189444", "CHEBI:36144", "species_189444", "CHEBI:36144", "SPAC14C4.07" ] }, "reaction_10741727": { "compartment": "compartment_70101", "id": "reaction_10741727", "reactome": "R-SPO-1454916", "name": "The ABCC family mediates organic anion transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_1454930" ], "products": [ "species_29370", "species_1454919", "species_29372" ], "modifiers": [ [ "species_10741724", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q10185", "SPAC3F10.11c", "Q9P7V2", "SPAC30.04c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10740150": { "compartment": "compartment_876", "id": "reaction_10740150", "reactome": "R-SPO-507868", "name": "Aquaporins passively transport water into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276" ], "products": [ "species_29356" ], "modifiers": [ [ "species_10740147", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10738220": { "compartment": "compartment_876", "id": "reaction_10738220", "reactome": "R-SPO-383190", "name": "HCO3- transport through ion channel", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_29356" ], "products": [ "species_29370", "species_425425", "species_29372" ], "modifiers": [ [ "species_10738217", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10745669": { "compartment": "compartment_70101", "id": "reaction_10745669", "reactome": "R-SPO-5339528", "name": "TUSC3 transports Mg2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114632" ], "products": [ "species_29926" ], "modifiers": [ [ "species_10745666", "catalyst" ] ], "additional_components": [ "SPAPB17E12.11" ] }, "reaction_10743514": { "compartment": "compartment_70101", "id": "reaction_10743514", "reactome": "R-SPO-2730692", "name": "CLCN4/5/6 exchange Cl- for H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_2731008" ], "products": [ "species_352022", "species_74722" ], "modifiers": [ [ "species_10743511", "catalyst" ] ], "additional_components": [ "O94287", "SPBC887.02", "O60159", "SPBC19C7.11" ] }, "reaction_10739264": { "compartment": "compartment_876", "id": "reaction_10739264", "reactome": "R-SPO-432074", "name": "Aquaporin-7 passively transports glycerol out of cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76116" ], "products": [ "species_192438" ], "modifiers": [ [ "species_10739261", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10749518": { "compartment": "compartment_70101", "id": "reaction_10749518", "reactome": "R-SPO-5692462", "name": "ATP13A1 transports Mn2+ from cytosol to ER lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29418", "species_29356" ], "products": [ "species_29370", "species_29372", "species_1981162" ], "modifiers": [ [ "species_10749515", "catalyst" ] ], "additional_components": [ "SPACUNK4.07c" ] }, "reaction_10754739": { "compartment": "compartment_876", "id": "reaction_10754739", "reactome": "R-SPO-8866851", "name": "CFTR transits to the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754733" ], "products": [ "species_10738217" ], "modifiers": [], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c", "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10739339": { "compartment": "compartment_876", "id": "reaction_10739339", "reactome": "R-SPO-437300", "name": "SLC31A1 transports Cu2+ from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_437295" ], "products": [ "species_209799" ], "modifiers": [ [ "species_10739336", "catalyst" ] ], "additional_components": [ "SPBC23G7.16" ] }, "reaction_10749496": { "compartment": "compartment_70101", "id": "reaction_10749496", "reactome": "R-SPO-5691131", "name": "CANDI binds CUL1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749492", "species_10735499" ], "products": [ "species_10749494" ], "modifiers": [], "additional_components": [ "SPAC1565.07c", "SPAC17G6.12", "Q9P3A8", "SPAC1565.07c", "O13790", "SPAC17G6.12" ] }, "reaction_10740297": { "compartment": "compartment_20699", "id": "reaction_10740297", "reactome": "R-SPO-742354", "name": "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162756" ], "products": [ "species_914003" ], "modifiers": [ [ "species_10740294", "catalyst" ] ], "additional_components": [ "SPBC1734.09" ] }, "reaction_10740281": { "compartment": "compartment_20699", "id": "reaction_10740281", "reactome": "R-SPO-741450", "name": "SLC35A3 exchanges UDP-GlcNAc for UMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_735698", "species_162756" ], "products": [ "species_109402", "species_914003" ], "modifiers": [ [ "species_10740278", "catalyst" ] ], "additional_components": [ "SPCC1795.03" ] }, "reaction_10734940": { "compartment": "compartment_70616", "id": "reaction_10734940", "reactome": "R-SPO-163215", "name": "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113593" ], "products": [ "species_113592", "species_113581" ], "modifiers": [ [ "species_10734937", "catalyst" ] ], "additional_components": [ "Q09188", "SPBC530.10c" ] }, "reaction_10741748": { "compartment": "compartment_876", "id": "reaction_10741748", "reactome": "R-SPO-1467457", "name": "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1131652", "species_113592", "species_29356" ], "products": [ "species_29370", "species_29372", "species_1467459" ], "modifiers": [ [ "species_10741745", "catalyst" ] ], "additional_components": [ "Q02592", "SPCC737.09c", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10740795": { "compartment": "compartment_20699", "id": "reaction_10740795", "reactome": "R-SPO-936895", "name": "ATP7B transports cytosolic Cu2+ to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29356", "species_209799" ], "products": [ "species_29370", "species_936901", "species_29372" ], "modifiers": [ [ "species_10740792", "catalyst" ] ], "additional_components": [ "SPBC29A3.01" ] }, "reaction_10740273": { "compartment": "compartment_20699", "id": "reaction_10740273", "reactome": "R-SPO-727759", "name": "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183" ], "products": [ "species_727753" ], "modifiers": [ [ "species_10740270", "catalyst" ] ], "additional_components": [ "SPBC21B10.09" ] }, "reaction_10740164": { "compartment": "compartment_876", "id": "reaction_10740164", "reactome": "R-SPO-507875", "name": "Aquaporins passively transport urea into cells", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_432019" ], "products": [ "species_29514" ], "modifiers": [ [ "species_10740159", "catalyst" ] ], "additional_components": [ "Q9P7T9", "SPAC977.17" ] }, "reaction_10747157": { "compartment": "compartment_984", "id": "reaction_10747157", "reactome": "R-SPO-5678706", "name": "ABCB4 transports PC from plasma membrane to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_429802", "species_29356" ], "products": [ "species_29370", "species_382539", "species_29372" ], "modifiers": [ [ "species_10747154", "catalyst" ] ], "additional_components": [ "Q02592", "SPCC737.09c", "Q9Y7M7", "SPBC9B6.09c", "P36619", "SPCC663.03" ] }, "reaction_10755815": { "compartment": "compartment_70101", "id": "reaction_10755815", "reactome": "R-SPO-8932851", "name": "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8932838" ], "products": [ "species_8932842" ], "modifiers": [ [ "species_10755812", "catalyst" ] ], "additional_components": [ "CHEBI:32513", "species_1131871", "species_29468", "CHEBI:32513", "species_1131871", "species_29468", "SPAC17C9.10" ] }, "reaction_10757945": { "compartment": "compartment_70101", "id": "reaction_10757945", "reactome": "R-SPO-9696271", "name": "RND1 binds effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738543", "species_10757941" ], "products": [ "species_10757943" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9UTL2", "SPAC144.14", "Q9USZ0", "SPBC1306.02", "Q9USR1", "SPBC577.08c", "Q9USI5", "SPCC645.14c", "P08647", "SPAC17H9.09c", "O43023", "SPBC354.09c", "Q9UTL2", "SPAC144.14", "Q9HE04", "SPAC20H4.11c", "Q9USZ0", "SPBC1306.02", "Q9USR1", "SPBC577.08c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9USI5", "SPCC645.14c", "P08647", "SPAC17H9.09c", "O43023", "SPBC354.09c" ] }, "reaction_10757947": { "compartment": "compartment_70101", "id": "reaction_10757947", "reactome": "R-SPO-9696274", "name": "RND1 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10738541" ], "products": [ "species_10738543" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10733685": { "compartment": "compartment_7660", "id": "reaction_10733685", "reactome": "R-SPO-83788", "name": "Binding of TFIIIC to Type 2 promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733480", "species_83747" ], "products": [ "species_10733683" ], "modifiers": [], "additional_components": [ "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733689": { "compartment": "compartment_7660", "id": "reaction_10733689", "reactome": "R-SPO-83790", "name": "Binding of TFIIIB to TFIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733683", "species_10733448" ], "products": [ "species_10733687" ], "modifiers": [], "additional_components": [ "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9UST7", "SPBC336.07", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733681": { "compartment": "compartment_7660", "id": "reaction_10733681", "reactome": "R-SPO-83723", "name": "Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733484", "species_10733448" ], "products": [ "species_10733486" ], "modifiers": [], "additional_components": [ "O13650", "SPBC8D2.07c", "Q9UST7", "SPBC336.07", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "Q9UST7", "SPBC336.07", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733547": { "compartment": "compartment_7660", "id": "reaction_10733547", "reactome": "R-SPO-76056", "name": "Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733543", "species_10733486" ], "products": [ "species_10733545" ], "modifiers": [], "additional_components": [ "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "O13877", "SPAC1B3.12c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74857", "SPCC18.07", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "Q9UST7", "SPBC336.07", "P17871", "SPAC3A11.12c", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O13650", "SPBC8D2.07c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "Q9P6R0", "SPBC13E7.10c", "O13877", "SPAC1B3.12c", "O74458", "SPCC16C4.14c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "O94481", "SPCC1919.14c", "Q92399", "SPBC14C8.12", "Q9UST7", "SPBC336.07", "O74857", "SPCC18.07", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10733693": { "compartment": "compartment_7660", "id": "reaction_10733693", "reactome": "R-SPO-83805", "name": "Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733543", "species_10733687" ], "products": [ "species_10733691" ], "modifiers": [], "additional_components": [ "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "O13877", "SPAC1B3.12c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74857", "SPCC18.07", "O13650", "SPBC8D2.07c", "O94481", "SPCC1919.14c", "P17871", "SPAC3A11.12c", "Q9UST7", "SPBC336.07", "Q9P6R0", "SPBC13E7.10c", "O74458", "SPCC16C4.14c", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c", "O13896", "SPAC22A12.05", "P36595", "SPCC1020.04c", "O13650", "SPBC8D2.07c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O94553", "SPCC290.02", "Q9C106", "SPAPB1E7.03", "Q8WZJ8", "SPBC839.12", "Q9P6R0", "SPBC13E7.10c", "O13877", "SPAC1B3.12c", "O74458", "SPCC16C4.14c", "Q9C0Z9", "SPAPB1E7.10", "O94666", "SPBC651.08c", "O94285", "SPBC2G5.07c", "Q10233", "SPAC4G9.08c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "O94481", "SPCC1919.14c", "Q92399", "SPBC14C8.12", "Q9UST7", "SPBC336.07", "O74857", "SPCC18.07", "A6X980", "SPAC1250.07", "O60174", "SPBC21H7.05", "O14229", "SPAC6F12.11c" ] }, "reaction_10736346": { "compartment": "compartment_876", "id": "reaction_10736346", "reactome": "R-SPO-196017", "name": "Dynamin is recruited to the gap junction plaque", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736046", "species_10736019" ], "products": [ "species_10736048" ], "modifiers": [], "additional_components": [ "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "O60054", "SPBC56F2.03", "P10989", "SPBC32H8.12c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q09718", "SPAC31A2.09c", "O60054", "SPBC56F2.03", "Q9URZ5", "SPAC767.01c", "P10989", "SPBC32H8.12c" ] }, "reaction_10739285": { "compartment": "compartment_17906", "id": "reaction_10739285", "reactome": "R-SPO-434382", "name": "ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_200993" ], "modifiers": [ [ "species_10739282", "catalyst" ] ], "additional_components": [ "Q9P7D7", "SPBP4H10.11c", "O60135", "SPBC18H10.02" ] }, "reaction_10737145": { "compartment": "compartment_876", "id": "reaction_10737145", "reactome": "R-SPO-202692", "name": "PIP3 binds to RhoA and activates it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10734488" ], "products": [ "species_10737143" ], "modifiers": [], "additional_components": [ "SPAC1F7.04", "Q09914", "SPAC1F7.04", "species_179838" ] }, "reaction_10742675": { "compartment": "compartment_12045", "id": "reaction_10742675", "reactome": "R-SPO-1855214", "name": "PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023856", "species_29356" ], "products": [ "species_114520", "species_1500596" ], "modifiers": [ [ "species_10742672", "catalyst" ] ], "additional_components": [ "species_74016", "P40977", "SPAC22F8.11" ] }, "reaction_10742665": { "compartment": "compartment_70101", "id": "reaction_10742665", "reactome": "R-SPO-1855205", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_114520", "species_29372" ], "modifiers": [ [ "species_10742662", "catalyst" ] ], "additional_components": [ "O94526", "SPBC609.02", "species_29926" ] }, "reaction_10742633": { "compartment": "compartment_70101", "id": "reaction_10742633", "reactome": "R-SPO-1855177", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10742630", "catalyst" ] ], "additional_components": [ "species_74016", "P40977", "SPAC22F8.11" ] }, "reaction_10742706": { "compartment": "compartment_876", "id": "reaction_10742706", "reactome": "R-SPO-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10742703", "catalyst" ] ], "additional_components": [ "species_74016", "P40977", "SPAC22F8.11" ] }, "reaction_10742681": { "compartment": "compartment_70101", "id": "reaction_10742681", "reactome": "R-SPO-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_994170", "species_29356" ], "products": [ "species_994123", "species_29372" ], "modifiers": [ [ "species_10742605", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "Q9USQ6", "SPBC577.13" ] }, "reaction_10756065": { "compartment": "compartment_876", "id": "reaction_10756065", "reactome": "R-SPO-8943279", "name": "GGT dimers hydrolyse GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247892", "species_109276" ], "products": [ "species_210382", "species_1247934" ], "modifiers": [ [ "species_10745932", "catalyst" ] ], "additional_components": [ "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10741599": { "compartment": "compartment_70101", "id": "reaction_10741599", "reactome": "R-SPO-1247935", "name": "OPLAH hydrolyses OPRO to L-Glu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1247942", "species_29356" ], "products": [ "species_29370", "species_29404", "species_29372" ], "modifiers": [ [ "species_10741596", "catalyst" ] ], "additional_components": [ "Q10094", "SPAC11D3.15" ] }, "reaction_10741589": { "compartment": "compartment_70101", "id": "reaction_10741589", "reactome": "R-SPO-1247910", "name": "CNDP2:2Mn2+ dimer hydrolyses CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1247904", "species_29356" ], "products": [ "species_29424", "species_111707" ], "modifiers": [ [ "species_10741586", "catalyst" ] ], "additional_components": [ "Q9P6I2", "SPBC1198.08", "species_113527" ] }, "reaction_10735542": { "compartment": "compartment_70101", "id": "reaction_10735542", "reactome": "R-SPO-174367", "name": "GCL ligates L-Glu to L-Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111707", "species_29404" ], "products": [ "species_29370", "species_174393", "species_29372" ], "modifiers": [ [ "species_10735539", "catalyst" ] ], "additional_components": [ "O94246", "SPCC737.06c", "Q09768", "SPAC22F3.10c" ] }, "reaction_10735581": { "compartment": "compartment_70101", "id": "reaction_10735581", "reactome": "R-SPO-174394", "name": "GSS:Mg2+ dimer synthesizes GSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_174393", "species_113592" ], "products": [ "species_29370", "species_29450", "species_29372" ], "modifiers": [ [ "species_10735578", "catalyst" ], [ "species_29450", "inhibitor" ] ], "additional_components": [ "P35669", "SPAC3F10.04", "species_29926" ] }, "reaction_10750414": { "compartment": "compartment_70101", "id": "reaction_10750414", "reactome": "R-SPO-6785928", "name": "CHAC1,2 cleaves GSH to OPRO and CysGly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450" ], "products": [ "species_1247904", "species_1247942" ], "modifiers": [ [ "species_10750411", "catalyst" ] ], "additional_components": [ "P87305", "SPBC31F10.03" ] }, "reaction_10757128": { "compartment": "compartment_17947", "id": "reaction_10757128", "reactome": "R-SPO-9033527", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757089", "species_10756376" ], "products": [ "species_10757091" ], "modifiers": [], "additional_components": [ "O60065", "SPBC13G1.03c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10" ] }, "reaction_10757083": { "compartment": "compartment_17947", "id": "reaction_10757083", "reactome": "R-SPO-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757067" ], "products": [ "species_10757081", "species_10756372" ], "modifiers": [], "additional_components": [ "O60065", "SPBC13G1.03c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "O94325", "SPBC725.07", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14077", "SPACUNK4.12c", "Q9Y7N4", "SPCC1450.07c", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O14136", "SPAC3C7.10", "O13717", "SPAC14C4.10c", "O14077", "SPACUNK4.12c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "Q9Y7N4", "SPCC1450.07c", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O13717", "SPAC14C4.10c", "O60065", "SPBC13G1.03c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10" ] }, "reaction_10757096": { "compartment": "compartment_17947", "id": "reaction_10757096", "reactome": "R-SPO-9033485", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757091" ], "products": [ "species_10741537", "species_10757093" ], "modifiers": [ [ "species_10757091", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P78798", "SPAC17D4.01", "P0C8R3", "SPAC589.10c", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O60065", "SPBC13G1.03c", "P0C8R3", "SPAC589.10c", "P78798", "SPAC17D4.01", "O94325", "SPBC725.07", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O14136", "SPAC3C7.10" ] }, "reaction_10757085": { "compartment": "compartment_17947", "id": "reaction_10757085", "reactome": "R-SPO-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757063", "species_10757065" ], "products": [ "species_10757067" ], "modifiers": [], "additional_components": [ "O14077", "SPACUNK4.12c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "Q9Y7N4", "SPCC1450.07c", "O94325", "SPBC725.07", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O13717", "SPAC14C4.10c", "O60065", "SPBC13G1.03c", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14136", "SPAC3C7.10", "O60065", "SPBC13G1.03c", "Q9US28", "SPBC12C2.03c", "O14254", "SPAC6G10.08", "O94325", "SPBC725.07", "O43029", "SPBC354.15", "Q09744", "SPBC12C2.03c", "Q9HDX2", "SPAPB1A11.03", "Q8TFH8", "SPAPB17E12.03", "Q9UUF0", "SPBC17A3.10", "O14077", "SPACUNK4.12c", "Q9Y7N4", "SPCC1450.07c", "Q9Y7M1", "SPBC725.04", "P55306", "SPCC757.07c", "P36587", "SPBC29A10.01", "O14136", "SPAC3C7.10", "O13717", "SPAC14C4.10c" ] }, "reaction_10736821": { "compartment": "compartment_70101", "id": "reaction_10736821", "reactome": "R-SPO-200423", "name": "pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736809", "species_113592" ], "products": [ "species_29370", "species_10736816" ], "modifiers": [ [ "species_10736818", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527", "P78820", "SPAC56E4.04c", "species_113527", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10755610": { "compartment": "compartment_70101", "id": "reaction_10755610", "reactome": "R-SPO-8876889", "name": "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10736809", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527" ] }, "reaction_10733326": { "compartment": "compartment_70101", "id": "reaction_10733326", "reactome": "R-SPO-75851", "name": "Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10733323", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527" ] }, "reaction_10736829": { "compartment": "compartment_17927", "id": "reaction_10736829", "reactome": "R-SPO-200424", "name": "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_201023", "species_201034" ], "products": [ "species_549207", "species_201050" ], "modifiers": [ [ "species_10736826", "catalyst" ] ], "additional_components": [ "SPBC29A3.11c" ] }, "reaction_10757932": { "compartment": "compartment_70101", "id": "reaction_10757932", "reactome": "R-SPO-9696267", "name": "RND3 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757928" ], "products": [ "species_10757930" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10729657": { "compartment": "compartment_70101", "id": "reaction_10729657", "reactome": "R-SPO-70286", "name": "UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29494", "species_29548" ], "products": [ "species_29410", "species_111294" ], "modifiers": [ [ "species_10729654", "catalyst" ] ], "additional_components": [ "P78811", "SPCC1322.04" ] }, "reaction_10729379": { "compartment": "compartment_7660", "id": "reaction_10729379", "reactome": "R-SPO-68954", "name": "Mcm2-7 is phosphorylated by DDK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728861", "species_29358" ], "products": [ "species_113582", "species_10729376" ], "modifiers": [ [ "species_10728818", "catalyst" ] ], "additional_components": [ "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "species_29372", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "P50582", "SPBC776.12c", "O59836", "SPCC550.13" ] }, "reaction_10728884": { "compartment": "compartment_7660", "id": "reaction_10728884", "reactome": "R-SPO-68916", "name": "DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728877", "species_10728792" ], "products": [ "species_10728879" ], "modifiers": [], "additional_components": [ "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "Q92373", "SPCC1753.01c", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "Q92374", "SPCC23B6.05c", "O74796", "SPBC2A9.12", "Q92372", "SPBC660.13c", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728903": { "compartment": "compartment_7660", "id": "reaction_10728903", "reactome": "R-SPO-68940", "name": "Cdt1 is displaced from the pre-replicative complex.", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728899" ], "products": [ "species_10728893", "species_10728873" ], "modifiers": [], "additional_components": [ "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "SPBC428.18", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728886": { "compartment": "compartment_7660", "id": "reaction_10728886", "reactome": "R-SPO-68917", "name": "Cdc45 associates with the pre-replicative complex at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728797", "species_10728875" ], "products": [ "species_10728877" ], "modifiers": [], "additional_components": [ "SPAC17D4.02", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10729381": { "compartment": "compartment_7660", "id": "reaction_10729381", "reactome": "R-SPO-68960", "name": "DNA polymerase epsilon binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68419", "species_10728764" ], "products": [ "species_10728766" ], "modifiers": [ [ "species_10728879", "catalyst" ] ], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "Q92373", "SPCC1753.01c", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "Q92374", "SPCC23B6.05c", "O74796", "SPBC2A9.12", "Q92372", "SPBC660.13c", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728888": { "compartment": "compartment_7660", "id": "reaction_10728888", "reactome": "R-SPO-68918", "name": "CDK and DDK associate with the Mcm10:pre-replicative complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728806", "species_10728818", "species_10728873" ], "products": [ "species_10728875" ], "modifiers": [], "additional_components": [ "P04551", "SPBC11B10.09", "P50582", "SPBC776.12c", "O59836", "SPCC550.13", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728901": { "compartment": "compartment_7660", "id": "reaction_10728901", "reactome": "R-SPO-68919", "name": "Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728823", "species_10728897" ], "products": [ "species_10728899" ], "modifiers": [], "additional_components": [ "SPBC1347.10", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "P41389", "SPAC1B2.05", "Q09142", "SPBC685.09", "P29458", "SPCC16A11.17", "P40382", "SPBC428.18", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P41411", "SPBC14C8.07c", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10728881": { "compartment": "compartment_7660", "id": "reaction_10728881", "reactome": "R-SPO-68914", "name": "DNA polymerase alpha:primase binds at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728766", "species_10728742" ], "products": [ "species_10728768" ], "modifiers": [ [ "species_10728879", "catalyst" ] ], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "Q92373", "SPCC1753.01c", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "Q92374", "SPCC23B6.05c", "O74796", "SPBC2A9.12", "Q92372", "SPBC660.13c", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c" ] }, "reaction_10745090": { "compartment": "compartment_7660", "id": "reaction_10745090", "reactome": "R-SPO-5082356", "name": "HSF1-mediated gene expression", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744254" ], "products": [ "species_10745068" ], "modifiers": [ [ "species_10745088", "catalyst" ], [ "species_10745078", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14330", "SPBC16E9.15", "P41887", "SPAC926.04c", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10745122": { "compartment": "compartment_7660", "id": "reaction_10745122", "reactome": "R-SPO-5082405", "name": "Phosphorylation of HSF1 at Ser326 induces transactivation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10744252" ], "products": [ "species_113582", "species_10745088" ], "modifiers": [ [ "species_10745119", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q9Y7K2", "SPBC216.07c", "P87141", "SPAC57A7.11", "O74184", "SPBC21B10.05c" ] }, "reaction_10742668": { "compartment": "compartment_7660", "id": "reaction_10742668", "reactome": "R-SPO-1855207", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023929" ], "products": [ "species_113582", "species_2023940" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742651": { "compartment": "compartment_70101", "id": "reaction_10742651", "reactome": "R-SPO-1855182", "name": "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10742646", "catalyst" ] ], "additional_components": [ "SPCC1672.06c" ] }, "reaction_10742712": { "compartment": "compartment_7660", "id": "reaction_10742712", "reactome": "R-SPO-1855224", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023940", "species_29358" ], "products": [ "species_113582", "species_2023941" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742814": { "compartment": "compartment_70101", "id": "reaction_10742814", "reactome": "R-SPO-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_2023974", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "CHEBI:62922", "species_1629740", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742641": { "compartment": "compartment_7660", "id": "reaction_10742641", "reactome": "R-SPO-1855181", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023922" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742603": { "compartment": "compartment_70101", "id": "reaction_10742603", "reactome": "R-SPO-1855166", "name": "PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023943", "species_29356" ], "products": [ "species_29372", "species_994141" ], "modifiers": [ [ "species_10742591", "catalyst" ] ], "additional_components": [ "species_1629736", "species_1629755", "CHEBI:62927", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742657": { "compartment": "compartment_70101", "id": "reaction_10742657", "reactome": "R-SPO-1855194", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629740" ], "products": [ "species_29370", "species_1629732" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742715": { "compartment": "compartment_70101", "id": "reaction_10742715", "reactome": "R-SPO-1855227", "name": "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629765" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742580": { "compartment": "compartment_70101", "id": "reaction_10742580", "reactome": "R-SPO-1855158", "name": "5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_113592" ], "products": [ "species_29370", "species_1629759" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742654": { "compartment": "compartment_70101", "id": "reaction_10742654", "reactome": "R-SPO-1855193", "name": "1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1629736" ], "products": [ "species_29370", "species_1629738" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742616": { "compartment": "compartment_7660", "id": "reaction_10742616", "reactome": "R-SPO-1855176", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023901" ], "products": [ "species_113582", "species_2023929" ], "modifiers": [ [ "species_10742613", "catalyst" ] ], "additional_components": [ "SPCC4B3.10c" ] }, "reaction_10742812": { "compartment": "compartment_70101", "id": "reaction_10742812", "reactome": "R-SPO-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023974", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "CHEBI:62922", "species_1629740", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742709": { "compartment": "compartment_70101", "id": "reaction_10742709", "reactome": "R-SPO-1855223", "name": "I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629755" ], "modifiers": [ [ "species_10742577", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742718": { "compartment": "compartment_7660", "id": "reaction_10742718", "reactome": "R-SPO-1855230", "name": "5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023922", "species_29358" ], "products": [ "species_113582", "species_2023948" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742678": { "compartment": "compartment_70101", "id": "reaction_10742678", "reactome": "R-SPO-1855216", "name": "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629770", "species_113592" ], "products": [ "species_29370", "species_1629740" ], "modifiers": [ [ "species_10742646", "catalyst" ] ], "additional_components": [ "SPCC1672.06c" ] }, "reaction_10742567": { "compartment": "compartment_7660", "id": "reaction_10742567", "reactome": "R-SPO-1855157", "name": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_2023932" ], "products": [ "species_113582", "species_2023931" ], "modifiers": [ [ "species_10742564", "catalyst" ] ], "additional_components": [ "O74561", "SPCC970.08", "Q9US14", "SPAC607.04" ] }, "reaction_10742600": { "compartment": "compartment_70101", "id": "reaction_10742600", "reactome": "R-SPO-1855165", "name": "(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2023968", "species_29356" ], "products": [ "species_1629765", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "CHEBI:62924", "species_2023931", "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742660": { "compartment": "compartment_70101", "id": "reaction_10742660", "reactome": "R-SPO-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1629765", "species_29356" ], "products": [ "species_1629770", "species_29372" ], "modifiers": [ [ "species_10742597", "catalyst" ] ], "additional_components": [ "Q09790", "SPAC13G6.14", "species_113527", "species_29926" ] }, "reaction_10742638": { "compartment": "compartment_70101", "id": "reaction_10742638", "reactome": "R-SPO-1855179", "name": "I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_994141" ], "products": [ "species_29370", "species_1629770" ], "modifiers": [ [ "species_10742635", "catalyst" ] ], "additional_components": [ "SPCC4B3.10c" ] }, "reaction_10742608": { "compartment": "compartment_70101", "id": "reaction_10742608", "reactome": "R-SPO-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_114520", "species_29356" ], "products": [ "species_1629739", "species_29372" ], "modifiers": [ [ "species_10742605", "catalyst" ] ], "additional_components": [ "O43001", "SPBC2G2.02", "Q9USQ6", "SPBC577.13" ] }, "reaction_10741541": { "compartment": "compartment_70101", "id": "reaction_10741541", "reactome": "R-SPO-1236970", "name": "Proteasomal clevage of exogenous antigen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1236719" ], "products": [ "species_983036", "species_8942986" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10733749": { "compartment": "compartment_70101", "id": "reaction_10733749", "reactome": "R-SPO-109702", "name": "PDPK1 phosphorylates AKT2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733734", "species_113592" ], "products": [ "species_29370", "species_10733746" ], "modifiers": [ [ "species_10733718", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10732851": { "compartment": "compartment_17940", "id": "reaction_10732851", "reactome": "R-SPO-74723", "name": "Endosome acidification", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_74722" ], "modifiers": [ [ "species_10732848", "catalyst" ] ], "additional_components": [ "P50515", "SPAC1B3.14", "O43046", "SPBC3B9.18c", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O59823", "SPCC965.03", "O14046", "SPAC2C4.13", "O13742", "SPAC16E8.07c", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q69Z14", "SPBC1685.16", "Q9HDW6", "SPAPB2B4.05" ] }, "reaction_10733720": { "compartment": "compartment_876", "id": "reaction_10733720", "reactome": "R-SPO-109701", "name": "PDPK1 binds PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733716", "species_179838" ], "products": [ "species_10733718" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10738628": { "compartment": "compartment_876", "id": "reaction_10738628", "reactome": "R-SPO-418574", "name": "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738468" ], "products": [ "species_10738625" ], "modifiers": [ [ "species_10738468", "catalyst" ] ], "additional_components": [ "species_29438", "Q04665", "SPAC23H3.13c", "species_111349", "Q04665", "SPAC23H3.13c", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10738681": { "compartment": "compartment_70101", "id": "reaction_10738681", "reactome": "R-SPO-419166", "name": "GEFs activate RhoA,B,C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738582", "species_29438" ], "products": [ "species_10738584", "species_29420" ], "modifiers": [ [ "species_10738678", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_111349", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q09763", "SPAC24H6.09", "O59679", "SPBC29A3.17", "Q9HGL2", "SPBC800.10c", "Q9USU1", "SPBC336.03", "P26674", "SPCC1442.01" ] }, "reaction_10738831": { "compartment": "compartment_70101", "id": "reaction_10738831", "reactome": "R-SPO-425861", "name": "Activation of Protein Kinase C novel isoforms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738827", "species_114519" ], "products": [ "species_10738829" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10734572": { "compartment": "compartment_876", "id": "reaction_10734572", "reactome": "R-SPO-114688", "name": "PLC-beta hydrolyses PIP2 to DAG and IP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734567" ], "products": [ "species_10734569" ], "modifiers": [ [ "species_10734143", "catalyst" ] ], "additional_components": [ "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c", "species_179856", "species_114520", "species_1500596", "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c", "species_29438", "P40977", "SPAC22F8.11", "Q04665", "SPAC23H3.13c" ] }, "reaction_10738483": { "compartment": "compartment_876", "id": "reaction_10738483", "reactome": "R-SPO-400015", "name": "Diacylgycerol activates Protein kinase C, alpha type", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734508", "species_114519" ], "products": [ "species_10738481" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10757183": { "compartment": "compartment_70101", "id": "reaction_10757183", "reactome": "R-SPO-9603279", "name": "PIP3 recruits PDK1 and AKT to the membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_179838", "species_10737088", "species_10738396" ], "products": [ "species_10757181" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c", "Q12701", "SPCC576.15c" ] }, "reaction_10738633": { "compartment": "compartment_876", "id": "reaction_10738633", "reactome": "R-SPO-418582", "name": "G alpha (q) auto-inactivates by hydrolysing GTP to GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734141" ], "products": [ "species_10738630" ], "modifiers": [ [ "species_10734141", "catalyst" ] ], "additional_components": [ "species_29438", "Q04665", "SPAC23H3.13c", "species_111349", "Q04665", "SPAC23H3.13c", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10756978": { "compartment": "compartment_70101", "id": "reaction_10756978", "reactome": "R-SPO-9020253", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024781", "species_29356" ], "products": [ "species_9024809" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:138649", "CHEBI:138648", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756976": { "compartment": "compartment_70101", "id": "reaction_10756976", "reactome": "R-SPO-9020252", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9024602", "species_29356" ], "products": [ "species_9024574" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:138179", "CHEBI:138614", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756982": { "compartment": "compartment_70101", "id": "reaction_10756982", "reactome": "R-SPO-9020258", "name": "LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024768" ], "products": [ "species_9024759" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:81565", "CHEBI:81564", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10756984": { "compartment": "compartment_70101", "id": "reaction_10756984", "reactome": "R-SPO-9020270", "name": "LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9024577" ], "products": [ "species_9024570" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "CHEBI:138616", "CHEBI:138615", "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10736344": { "compartment": "compartment_70101", "id": "reaction_10736344", "reactome": "R-SPO-195664", "name": "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_195691" ], "products": [ "species_29366", "species_195655", "species_29356" ], "modifiers": [ [ "species_10736341", "catalyst" ] ], "additional_components": [ "O13666", "SPBC27B12.03c", "O94457", "SPAC1687.16c" ] }, "reaction_10737982": { "compartment": "compartment_70101", "id": "reaction_10737982", "reactome": "R-SPO-372449", "name": "phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] => phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_372364", "species_76190" ], "products": [ "species_29654", "species_29492" ], "modifiers": [ [ "species_10733305", "catalyst" ] ], "additional_components": [ "SPAC19G12.05" ] }, "reaction_10729759": { "compartment": "compartment_70101", "id": "reaction_10729759", "reactome": "R-SPO-70454", "name": "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75970" ], "products": [ "species_29578" ], "modifiers": [ [ "species_10729756", "catalyst" ] ], "additional_components": [ "P07669", "SPCC24B10.21" ] }, "reaction_10730569": { "compartment": "compartment_5460", "id": "reaction_10730569", "reactome": "R-SPO-71783", "name": "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113587", "species_113529" ], "products": [ "species_113526", "species_113544" ], "modifiers": [ [ "species_10730123", "catalyst" ] ], "additional_components": [ "Q9Y7R8", "SPCC306.08c" ] }, "reaction_10729720": { "compartment": "compartment_70101", "id": "reaction_10729720", "reactome": "R-SPO-70420", "name": "HK1,2,3,GCK phosphorylate Glc to form G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_70113" ], "products": [ "species_70106", "species_29370", "species_30537" ], "modifiers": [ [ "species_10729717", "catalyst" ] ], "additional_components": [ "P50521", "SPAC4F8.07c", "Q09756", "SPAC24H6.04" ] }, "reaction_10751283": { "compartment": "compartment_70101", "id": "reaction_10751283", "reactome": "R-SPO-6798335", "name": "BPGM dimer isomerises 1,3BPG to 2,3BPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800" ], "products": [ "species_6798337" ], "modifiers": [ [ "species_10751280", "catalyst" ] ], "additional_components": [ "P36623", "SPAC26F1.06" ] }, "reaction_10729809": { "compartment": "compartment_70101", "id": "reaction_10729809", "reactome": "R-SPO-70479", "name": "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30014", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10729806", "catalyst" ], [ "species_76577", "inhibitor" ] ], "additional_components": [ "species_29926", "P09202", "SPBC1198.14c" ] }, "reaction_10729793": { "compartment": "compartment_70101", "id": "reaction_10729793", "reactome": "R-SPO-70475", "name": "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10729788", "catalyst" ] ], "additional_components": [ "P78917", "SPBC1604.05" ] }, "reaction_10730470": { "compartment": "compartment_70101", "id": "reaction_10730470", "reactome": "R-SPO-71670", "name": "phosphoenolpyruvate + ADP => pyruvate + ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29370", "species_29492" ], "products": [ "species_113592", "species_29398" ], "modifiers": [ [ "species_10730467", "catalyst" ], [ "species_30014", "catalyst" ], [ "species_76183", "inhibitor" ], [ "species_30389", "inhibitor" ], [ "species_29358", "inhibitor" ] ], "additional_components": [ "Q10208", "SPAC4H3.10c", "species_74126", "species_29926" ] }, "reaction_10735464": { "compartment": "compartment_13231", "id": "reaction_10735464", "reactome": "R-SPO-170825", "name": "glucokinase [nucleoplasm] => glucokinase [cytosol]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735462" ], "products": [ "species_10729703" ], "modifiers": [], "additional_components": [ "P50521", "SPAC4F8.07c", "Q09756", "SPAC24H6.04", "P50521", "SPAC4F8.07c", "Q09756", "SPAC24H6.04" ] }, "reaction_10756422": { "compartment": "compartment_70101", "id": "reaction_10756422", "reactome": "R-SPO-8955760", "name": "PGM2L1:Mg2+ phosphorylates G6P to G1,6BP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29800", "species_30537" ], "products": [ "species_70106", "species_29728", "species_8955759" ], "modifiers": [ [ "species_10729642", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10730609": { "compartment": "compartment_70101", "id": "reaction_10730609", "reactome": "R-SPO-71850", "name": "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_29800" ], "products": [ "species_113592", "species_29728" ], "modifiers": [ [ "species_10729826", "catalyst" ] ], "additional_components": [ "O60101", "SPBC14F5.04c", "species_29926" ] }, "reaction_10729856": { "compartment": "compartment_70101", "id": "reaction_10729856", "reactome": "R-SPO-70494", "name": "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29492", "species_29356" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10729853", "catalyst" ] ], "additional_components": [ "P40370", "SPBC1815.01", "Q8NKC2", "SPBPB21E7.01c", "species_29926" ] }, "reaction_10730452": { "compartment": "compartment_70101", "id": "reaction_10730452", "reactome": "R-SPO-71654", "name": "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29728" ], "products": [ "species_30485" ], "modifiers": [ [ "species_10730341", "catalyst" ] ], "additional_components": [ "P36623", "SPAC26F1.06" ] }, "reaction_10729813": { "compartment": "compartment_70101", "id": "reaction_10729813", "reactome": "R-SPO-70482", "name": "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_29800" ], "products": [ "species_29578", "species_29360", "species_29372" ], "modifiers": [ [ "species_10729746", "catalyst" ] ], "additional_components": [ "O43026", "SPBC354.12", "P78958", "SPBC32F12.11" ] }, "reaction_10729781": { "compartment": "compartment_70101", "id": "reaction_10729781", "reactome": "R-SPO-70467", "name": "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30014" ], "modifiers": [ [ "species_10729778", "catalyst" ], [ "species_29370", "catalyst" ], [ "species_76577", "catalyst" ], [ "species_30533", "catalyst" ], [ "species_113592", "inhibitor" ], [ "species_76190", "inhibitor" ] ], "additional_components": [ "O42938", "SPBC16H5.02" ] }, "reaction_10729631": { "compartment": "compartment_70101", "id": "reaction_10729631", "reactome": "R-SPO-70262", "name": "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30533", "species_29356" ], "products": [ "species_29372", "species_29512" ], "modifiers": [ [ "species_10729628", "catalyst" ] ], "additional_components": [ "Q9URZ7", "SPAC732.02c" ] }, "reaction_10729866": { "compartment": "compartment_5460", "id": "reaction_10729866", "reactome": "R-SPO-70501", "name": "Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29376", "species_113557", "species_113593" ], "products": [ "species_113548", "species_113581", "species_113587" ], "modifiers": [ [ "species_10729863", "catalyst" ], [ "species_113559", "catalyst" ] ], "additional_components": [ "Q9UUE1", "SPBC17G9.11c", "species_199207", "species_113527" ] }, "reaction_10729960": { "compartment": "compartment_70101", "id": "reaction_10729960", "reactome": "R-SPO-70592", "name": "PXLP-K259-GOT1 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_29406" ], "products": [ "species_29404", "species_76213" ], "modifiers": [ [ "species_10729955", "catalyst" ] ], "additional_components": [ "O42652", "SPAC10F6.13c" ] }, "reaction_10730605": { "compartment": "compartment_70101", "id": "reaction_10730605", "reactome": "R-SPO-71802", "name": "D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29512" ], "products": [ "species_29370", "species_30533" ], "modifiers": [ [ "species_10730602", "catalyst" ], [ "species_30533", "catalyst" ] ], "additional_components": [ "Q9UTK9", "SPAC144.17c", "Q9URZ7", "SPAC732.02c" ] }, "reaction_10741799": { "compartment": "compartment_12045", "id": "reaction_10741799", "reactome": "R-SPO-1482545", "name": "2-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741812": { "compartment": "compartment_12045", "id": "reaction_10741812", "reactome": "R-SPO-1482571", "name": "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_29356" ], "products": [ "species_1524023", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10733703": { "compartment": "compartment_70101", "id": "reaction_10733703", "reactome": "R-SPO-109624", "name": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500173", "species_113592" ], "products": [ "species_29370", "species_500088" ], "modifiers": [ [ "species_10733700", "catalyst" ] ], "additional_components": [ "species_83909", "CHEBI:17256", "species_76577", "species_109386", "P78825", "SPCC338.14", "species_29926" ] }, "reaction_10732725": { "compartment": "compartment_70101", "id": "reaction_10732725", "reactome": "R-SPO-74213", "name": "APRT catalyzes the conversion of adenine to AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73566", "species_83951" ], "products": [ "species_111294", "species_76577" ], "modifiers": [ [ "species_10732722", "catalyst" ] ], "additional_components": [ "O42842", "SPAC23A1.03" ] }, "reaction_10733571": { "compartment": "compartment_70101", "id": "reaction_10733571", "reactome": "R-SPO-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76577", "species_29356" ], "products": [ "species_29602", "species_31633" ], "modifiers": [ [ "species_10733568", "catalyst" ] ], "additional_components": [ "P50998", "SPBC106.04" ] }, "reaction_10734236": { "compartment": "compartment_70101", "id": "reaction_10734236", "reactome": "R-SPO-112033", "name": "PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113599", "species_500244" ], "products": [ "species_500172", "species_29372" ], "modifiers": [ [ "species_10732732", "catalyst" ] ], "additional_components": [ "species_112016", "CHEBI:58576", "CHEBI:28997", "CHEBI:17596", "Q9UTG1", "SPAC1805.16c" ] }, "reaction_10734238": { "compartment": "compartment_70101", "id": "reaction_10734238", "reactome": "R-SPO-112034", "name": "PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500244", "species_83956" ], "products": [ "species_500245", "species_29372" ], "modifiers": [ [ "species_10732732", "catalyst" ] ], "additional_components": [ "species_112016", "CHEBI:58576", "CHEBI:17172", "CHEBI:16750", "Q9UTG1", "SPAC1805.16c" ] }, "reaction_10742023": { "compartment": "compartment_12045", "id": "reaction_10742023", "reactome": "R-SPO-1482892", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741900": { "compartment": "compartment_12045", "id": "reaction_10741900", "reactome": "R-SPO-1482646", "name": "2-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498729", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10741895", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741999": { "compartment": "compartment_12045", "id": "reaction_10741999", "reactome": "R-SPO-1482828", "name": "PE is hydrolyzed to 2-acyl LPE by PLA2[4]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498729", "species_1524021" ], "modifiers": [ [ "species_10741996", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742019": { "compartment": "compartment_12045", "id": "reaction_10742019", "reactome": "R-SPO-1482884", "name": "PE is hydrolyzed to 1-acyl LPE by PLA2[2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_29356" ], "products": [ "species_1498738", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741905": { "compartment": "compartment_12045", "id": "reaction_10741905", "reactome": "R-SPO-1482667", "name": "1-acyl LPE is acylated to PE by LPEAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498738", "species_1500578" ], "products": [ "species_76194", "species_1500581" ], "modifiers": [ [ "species_10741895", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10749926": { "compartment": "compartment_70101", "id": "reaction_10749926", "reactome": "R-SPO-5694583", "name": "ABHD4 hydrolyses NAPE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_5694568" ], "products": [ "species_5694580", "species_5694567" ], "modifiers": [ [ "species_10749923", "catalyst" ] ], "additional_components": [ "SPAC6G10.03c" ] }, "reaction_10743442": { "compartment": "compartment_70101", "id": "reaction_10743442", "reactome": "R-SPO-2534096", "name": "METAP1/2 demethylates GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743423" ], "products": [ "species_174390", "species_10743408" ], "modifiers": [ [ "species_10743439", "catalyst" ] ], "additional_components": [ "SPAC23H3.13c", "SPAC23H3.13c", "O60085", "SPBC14C8.03", "O59730", "SPBC3E7.10", "species_880069" ] }, "reaction_10743483": { "compartment": "compartment_70101", "id": "reaction_10743483", "reactome": "R-SPO-2586748", "name": "GUCA binds Ca2+ to form GUCA:Ca2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_74016", "species_10743469" ], "products": [ "species_10743481" ], "modifiers": [], "additional_components": [ "SPAC18B11.04", "species_74016", "Q09711", "SPAC18B11.04" ] }, "reaction_10743421": { "compartment": "compartment_70101", "id": "reaction_10743421", "reactome": "R-SPO-2534087", "name": "NMT1/2 transfer MYS to GNAT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2534019", "species_10743408" ], "products": [ "species_76194", "species_10743411" ], "modifiers": [ [ "species_10743416", "catalyst" ] ], "additional_components": [ "SPAC23H3.13c", "SPAC23H3.13c", "SPBC2G2.11" ] }, "reaction_10737739": { "compartment": "compartment_70101", "id": "reaction_10737739", "reactome": "R-SPO-266072", "name": "LTA4 is hydolysed to LTB4 by LTA4H", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265281", "species_29356" ], "products": [ "species_266056" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10737682": { "compartment": "compartment_876", "id": "reaction_10737682", "reactome": "R-SPO-266012", "name": "LTD4 is converted to LTE4 by DPEP1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_266074" ], "products": [ "species_266029", "species_266033" ], "modifiers": [ [ "species_10737679", "catalyst" ] ], "additional_components": [ "O59832", "SPCC965.12", "species_442320", "O14124", "SPCC965.12" ] }, "reaction_10737721": { "compartment": "compartment_876", "id": "reaction_10737721", "reactome": "R-SPO-266046", "name": "GGT1, 5 dimers hydrolyse LTC4 to LTD4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266013", "species_109276" ], "products": [ "species_210382", "species_266074" ], "modifiers": [ [ "species_10737718", "catalyst" ] ], "additional_components": [ "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10737729": { "compartment": "compartment_876", "id": "reaction_10737729", "reactome": "R-SPO-266070", "name": "LTC4 is exported from the cytosol by ABCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_266066" ], "products": [ "species_266013" ], "modifiers": [ [ "species_10737726", "catalyst" ] ], "additional_components": [ "SPAC3F10.11c" ] }, "reaction_10731420": { "compartment": "compartment_7660", "id": "reaction_10731420", "reactome": "R-SPO-72185", "name": "mRNA polyadenylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731415", "species_29358" ], "products": [ "species_10731327", "species_10731322", "species_10731417", "species_10731317" ], "modifiers": [ [ "species_10731327", "catalyst" ] ], "additional_components": [ "Q9P7J4", "SPCC24B10.11c", "Q09176", "SPAP8A3.06", "O74733", "SPBC1709.08", "Q09801", "SPAC22G7.10", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q9HEQ9", "SPBC660.11", "O74740", "SPBC1709.15c", "Q10267", "SPAC13G7.03", "Q10295", "SPBC646.04", "P36629", "SPBC146.07", "O14327", "SPBC16E9.12c", "Q09779", "SPAC1D4.14", "C6Y4C0", "SPAC222.18", "Q9P383", "SPBC13A2.01c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9UTD1", "SPAC227.08c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "SPBC646.04", "SPBC16E9.12c", "Q9P7J4", "SPCC24B10.11c", "P36629", "SPBC146.07", "Q09176", "SPAP8A3.06", "Q09779", "SPAC1D4.14", "Q9P383", "SPBC13A2.01c", "C6Y4C0", "SPAC222.18", "Q9USY2", "SPBC1861.04c", "O13792", "SPAC17G6.14c", "Q10055", "SPAC1F5.10", "Q1MTR2", "SPBC13G1.14c", "Q9Y7Y2", "SPBC365.05c", "Q9P774", "SPBC1711.17", "Q9USL1", "SPCC18B5.10c", "Q9URV0", "SPCC126.11c", "O43037", "SPBC3B9.08c", "O94403", "SPCC126.11c", "species_113592", "O74871", "SPCC31H12.03c", "O43071", "SPBC6B1.10", "Q9URT2", "SPCP25A2.03", "O14253", "SPAC6G10.07", "Q9HEQ9", "SPBC660.11", "Q10267", "SPAC13G7.03", "Q9UTD1", "SPAC227.08c", "O74733", "SPBC1709.08", "Q9UTN4", "SPAC12G12.14c", "O13794", "SPAC17G6.16c", "Q09801", "SPAC22G7.10", "O74740", "SPBC1709.15c", "SPBC646.04" ] }, "reaction_10730232": { "compartment": "compartment_70101", "id": "reaction_10730232", "reactome": "R-SPO-71249", "name": "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_31503" ], "products": [ "species_29424", "species_31311" ], "modifiers": [ [ "species_10730229", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c" ] }, "reaction_10750452": { "compartment": "compartment_17951", "id": "reaction_10750452", "reactome": "R-SPO-6787811", "name": "HAO2 tetramer oxidises 2OH-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6787810", "species_113535" ], "products": [ "species_6787814", "species_113575" ], "modifiers": [ [ "species_10750449", "catalyst" ] ], "additional_components": [ "Q9HDX2", "SPAPB1A11.03" ] }, "reaction_10738303": { "compartment": "compartment_17951", "id": "reaction_10738303", "reactome": "R-SPO-389611", "name": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389594" ], "products": [ "species_389578", "species_389636" ], "modifiers": [ [ "species_10738300", "catalyst" ] ], "additional_components": [ "species_29480", "Q9Y7M1", "SPBC725.04", "species_29926" ] }, "reaction_10756425": { "compartment": "compartment_5460", "id": "reaction_10756425", "reactome": "R-SPO-8955817", "name": "PRODH2 oxidises HPRO to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215", "species_113597" ], "products": [ "species_164934", "species_113521", "species_113590" ], "modifiers": [ [ "species_10750340", "catalyst" ] ], "additional_components": [ "SPCC70.03c" ] }, "reaction_10730032": { "compartment": "compartment_5460", "id": "reaction_10730032", "reactome": "R-SPO-70670", "name": "PRODH oxidises L-Pro to 1PYR-5COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_379717", "species_113597" ], "products": [ "species_164934", "species_113529", "species_113590" ], "modifiers": [ [ "species_10730029", "catalyst" ] ], "additional_components": [ "SPCC70.03c" ] }, "reaction_10740192": { "compartment": "compartment_7660", "id": "reaction_10740192", "reactome": "R-SPO-517705", "name": "p-S318,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739886", "species_517622" ], "products": [ "species_10740190" ], "modifiers": [], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03" ] }, "reaction_10739891": { "compartment": "compartment_7660", "id": "reaction_10739891", "reactome": "R-SPO-450533", "name": "PKCdelta phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10730941" ], "products": [ "species_113582", "species_10739886" ], "modifiers": [ [ "species_10739888", "catalyst" ] ], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "SPBC12D12.04c" ] }, "reaction_10739874": { "compartment": "compartment_7660", "id": "reaction_10739874", "reactome": "R-SPO-450494", "name": "HuR binds mRNAs in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450613", "species_10730941" ], "products": [ "species_10739872" ], "modifiers": [], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03" ] }, "reaction_10739908": { "compartment": "compartment_7660", "id": "reaction_10739908", "reactome": "R-SPO-450550", "name": "PKCalpha phosphorylates HuR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10730941" ], "products": [ "species_113582", "species_10739899" ], "modifiers": [ [ "species_10739905", "catalyst" ] ], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10740188": { "compartment": "compartment_7660", "id": "reaction_10740188", "reactome": "R-SPO-517674", "name": "p-S158,221-HuR binds mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739899", "species_450605" ], "products": [ "species_10740186" ], "modifiers": [], "additional_components": [ "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03", "Q9UT83", "SPAC343.07", "P78795", "SPBC18H10.03" ] }, "reaction_10729539": { "compartment": "compartment_7660", "id": "reaction_10729539", "reactome": "R-SPO-69173", "name": "Joining of adjacent Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_68452" ], "products": [ "species_69172" ], "modifiers": [ [ "species_10729536", "catalyst" ] ], "additional_components": [ "SPAC20G8.01" ] }, "reaction_10729463": { "compartment": "compartment_7660", "id": "reaction_10729463", "reactome": "R-SPO-69063", "name": "Loading of PCNA - Sliding Clamp Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729459", "species_29358", "species_10729450" ], "products": [ "species_113582", "species_10729461" ], "modifiers": [], "additional_components": [ "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09" ] }, "reaction_10729493": { "compartment": "compartment_7660", "id": "reaction_10729493", "reactome": "R-SPO-69074", "name": "Formation of Processive Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729465", "species_10729489" ], "products": [ "species_10729491" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "Q03392", "SPBC16D10.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10729502": { "compartment": "compartment_7660", "id": "reaction_10729502", "reactome": "R-SPO-69127", "name": "Formation of the Flap Intermediate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729495" ], "products": [ "species_10729500" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10729467": { "compartment": "compartment_7660", "id": "reaction_10729467", "reactome": "R-SPO-69068", "name": "RFC dissociates after sliding clamp formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729461" ], "products": [ "species_10729465", "species_10729448" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "Q03392", "SPBC16D10.09", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c" ] }, "reaction_10729517": { "compartment": "compartment_7660", "id": "reaction_10729517", "reactome": "R-SPO-69142", "name": "Recruitment of Dna2 endonuclease", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729506", "species_10729513" ], "products": [ "species_10729515" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "SPBC16D10.04c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "Q9URU2", "SPBC16D10.04c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c" ] }, "reaction_10729498": { "compartment": "compartment_7660", "id": "reaction_10729498", "reactome": "R-SPO-69116", "name": "Formation of Okazaki fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729491" ], "products": [ "species_10729495" ], "modifiers": [ [ "species_10729489", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04" ] }, "reaction_10729508": { "compartment": "compartment_7660", "id": "reaction_10729508", "reactome": "R-SPO-69140", "name": "RPA binds to the Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729504", "species_10729500" ], "products": [ "species_10729506" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c" ] }, "reaction_10729531": { "compartment": "compartment_7660", "id": "reaction_10729531", "reactome": "R-SPO-69152", "name": "Removal of remaining Flap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729519" ], "products": [ "species_10729523" ], "modifiers": [ [ "species_10729528", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "SPAC3G6.06c" ] }, "reaction_10729521": { "compartment": "compartment_7660", "id": "reaction_10729521", "reactome": "R-SPO-69144", "name": "Removal of RNA primer and dissociation of RPA and Dna2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729515" ], "products": [ "species_418075", "species_29626", "species_418076", "species_10729504", "species_10729519", "species_164121", "species_10729513" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "Q92373", "SPCC1753.01c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "Q9URU2", "SPBC16D10.04c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O59835", "SPBC12D12.02c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q03392", "SPBC16D10.09", "SPBC16D10.04c" ] }, "reaction_10729452": { "compartment": "compartment_7660", "id": "reaction_10729452", "reactome": "R-SPO-69053", "name": "RFC binding displaces Pol Alpha", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729371", "species_10729448" ], "products": [ "species_10729450" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c" ] }, "reaction_10754222": { "compartment": "compartment_70101", "id": "reaction_10754222", "reactome": "R-SPO-8853496", "name": "SCF:FBXL7 binds AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754218", "species_10754213" ], "products": [ "species_10754220" ], "modifiers": [], "additional_components": [ "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c" ] }, "reaction_10754274": { "compartment": "compartment_70101", "id": "reaction_10754274", "reactome": "R-SPO-8854041", "name": "SCF-FBXL7 ubiquitinates AURKA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729165", "species_10754220" ], "products": [ "species_10754271" ], "modifiers": [ [ "species_10754220", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c" ] }, "reaction_10754276": { "compartment": "compartment_70101", "id": "reaction_10754276", "reactome": "R-SPO-8854044", "name": "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754271" ], "products": [ "species_10754213", "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "O59790", "SPCC320.13c", "O13959", "SPAC23H4.18c", "Q9Y709", "SPBC409.05", "O13790", "SPAC17G6.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10732603": { "compartment": "compartment_5460", "id": "reaction_10732603", "reactome": "R-SPO-73918", "name": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73871", "species_113559" ], "products": [ "species_29374", "species_73917" ], "modifiers": [ [ "species_10732600", "catalyst" ] ], "additional_components": [ "SPAC4F8.14c" ] }, "reaction_10732595": { "compartment": "compartment_5460", "id": "reaction_10732595", "reactome": "R-SPO-73912", "name": "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73909", "species_29362", "species_113529" ], "products": [ "species_73911", "species_113526" ], "modifiers": [ [ "species_10732592", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10736725": { "compartment": "compartment_7660", "id": "reaction_10736725", "reactome": "R-SPO-199839", "name": "AKT can phosphorylate RSK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10736698" ], "products": [ "species_113582", "species_10736702" ], "modifiers": [ [ "species_10736722", "catalyst" ] ], "additional_components": [ "SPCC4G3.08", "SPCC4G3.08", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10756118": { "compartment": "compartment_70101", "id": "reaction_10756118", "reactome": "R-SPO-8948757", "name": "AKT phosphorylates MKRN1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741188" ], "products": [ "species_29370", "species_10756116" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "O74463", "SPCC1739.01", "P41000", "SPAC3A11.02", "O74463", "SPCC1739.01", "P41000", "SPAC3A11.02", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10743069": { "compartment": "compartment_70101", "id": "reaction_10743069", "reactome": "R-SPO-2219524", "name": "PDPK1 binds PIP2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737088", "species_179856" ], "products": [ "species_10743067" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_179856", "Q12701", "SPCC576.15c" ] }, "reaction_10752710": { "compartment": "compartment_70101", "id": "reaction_10752710", "reactome": "R-SPO-6807206", "name": "USP13 and OTUD3 deubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752707", "species_29356" ], "products": [ "species_10736691", "species_10729165" ], "modifiers": [ [ "species_10750094", "catalyst" ] ], "additional_components": [ "SPBC609.02", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC6B1.06c" ] }, "reaction_10752676": { "compartment": "compartment_70101", "id": "reaction_10752676", "reactome": "R-SPO-6807105", "name": "Monoubiquitinated PTEN translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752670" ], "products": [ "species_10752674" ], "modifiers": [], "additional_components": [ "SPBC609.02", "SPBC609.02" ] }, "reaction_10753807": { "compartment": "compartment_70101", "id": "reaction_10753807", "reactome": "R-SPO-8850992", "name": "Proteasome degrades polyubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753805" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "O94526", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10753445": { "compartment": "compartment_70101", "id": "reaction_10753445", "reactome": "R-SPO-6811504", "name": "AKT1 dephosphorylation by PP2A-B56-beta,gamma", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736495", "species_29356" ], "products": [ "species_10738388", "species_29372" ], "modifiers": [ [ "species_10753440", "catalyst" ], [ "species_1806240", "inhibitor" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10428", "SPCC188.02", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "P78759", "SPAC6F12.12" ] }, "reaction_10752688": { "compartment": "compartment_7660", "id": "reaction_10752688", "reactome": "R-SPO-6807126", "name": "Deubiquitinated PTEN translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752683" ], "products": [ "species_10736691" ], "modifiers": [], "additional_components": [ "SPBC609.02", "SPBC609.02" ] }, "reaction_10736540": { "compartment": "compartment_876", "id": "reaction_10736540", "reactome": "R-SPO-198314", "name": "DAG stimulates protein kinase C-delta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10736518" ], "products": [ "species_29370", "species_10736537" ], "modifiers": [ [ "species_10736518", "catalyst" ], [ "species_112275", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10736556": { "compartment": "compartment_70101", "id": "reaction_10736556", "reactome": "R-SPO-198609", "name": "AKT phosphorylates TSC2, inhibiting it", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735151" ], "products": [ "species_29370", "species_10736554" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "SPAC630.13c", "SPAC630.13c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10753795": { "compartment": "compartment_70101", "id": "reaction_10753795", "reactome": "R-SPO-8850945", "name": "Casein kinase II phosphorylates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_113592" ], "products": [ "species_10753793", "species_29370" ], "modifiers": [ [ "species_10743403", "catalyst" ] ], "additional_components": [ "SPBC609.02", "SPBC609.02", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11" ] }, "reaction_10756085": { "compartment": "compartment_13231", "id": "reaction_10756085", "reactome": "R-SPO-8944457", "name": "MAF1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756078" ], "products": [ "species_10756076" ], "modifiers": [], "additional_components": [ "SPAC31G5.12c", "SPAC31G5.12c" ] }, "reaction_10752681": { "compartment": "compartment_70101", "id": "reaction_10752681", "reactome": "R-SPO-6807106", "name": "PTEN undergoes monoubiquitination", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_10729165" ], "products": [ "species_10752670" ], "modifiers": [ [ "species_10752678", "catalyst" ] ], "additional_components": [ "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC609.02", "Q9UTG2", "SPAC1805.15c", "O14064", "SPCC962.02c", "Q92462", "SPAC11G7.02", "O14326", "SPBC16E9.11c" ] }, "reaction_10736552": { "compartment": "compartment_70101", "id": "reaction_10736552", "reactome": "R-SPO-198599", "name": "AKT phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736545", "species_113592" ], "products": [ "species_29370", "species_10736549" ], "modifiers": [ [ "species_10736505", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10756121": { "compartment": "compartment_70101", "id": "reaction_10756121", "reactome": "R-SPO-8948775", "name": "MKRN1 polyubiquitinates PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_10729165" ], "products": [ "species_10752707" ], "modifiers": [ [ "species_10756116", "catalyst" ] ], "additional_components": [ "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC609.02", "O74463", "SPCC1739.01", "P41000", "SPAC3A11.02" ] }, "reaction_10752686": { "compartment": "compartment_7660", "id": "reaction_10752686", "reactome": "R-SPO-6807118", "name": "USP7 deubiquitinates monoubiquitinated PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752674", "species_113518" ], "products": [ "species_10752683", "species_10729044" ], "modifiers": [ [ "species_10747825", "catalyst" ] ], "additional_components": [ "SPBC609.02", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPCC188.08c" ] }, "reaction_10752704": { "compartment": "compartment_70101", "id": "reaction_10752704", "reactome": "R-SPO-6807134", "name": "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736691", "species_10729165" ], "products": [ "species_10752691" ], "modifiers": [ [ "species_10752701", "catalyst" ] ], "additional_components": [ "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC609.02", "Q9UTG2", "SPAC1805.15c", "O14064", "SPCC962.02c", "Q92462", "SPAC11G7.02", "O14326", "SPBC16E9.11c" ] }, "reaction_10757421": { "compartment": "compartment_7660", "id": "reaction_10757421", "reactome": "R-SPO-9632910", "name": "ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744302" ], "products": [ "species_10736630" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "P27638", "SPAC31G5.09c" ] }, "reaction_10757419": { "compartment": "compartment_876", "id": "reaction_10757419", "reactome": "R-SPO-9632858", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10757406" ], "products": [ "species_29370", "species_10757416" ], "modifiers": [ [ "species_10757406", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "species_179838", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_179838", "P36582", "SPAC17G8.14c", "Q12701", "SPCC576.15c", "P36583", "SPBC12D12.04c", "species_179838", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c" ] }, "reaction_10744869": { "compartment": "compartment_7660", "id": "reaction_10744869", "reactome": "R-SPO-4570467", "name": "SUMOylation of NOP58 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744858" ], "products": [ "species_10743639", "species_10744867" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC23G3.06", "SPAC30D11.13", "O13351", "SPBC365.06", "Q9P7S7", "SPAC23G3.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744879": { "compartment": "compartment_7660", "id": "reaction_10744879", "reactome": "R-SPO-4570493", "name": "RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10730960" ], "products": [ "species_10743639", "species_10744877" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC3H8.09c", "SPAC30D11.13", "O13351", "SPBC365.06", "Q10145", "SPAC3H8.09c", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10738944": { "compartment": "compartment_7660", "id": "reaction_10738944", "reactome": "R-SPO-427527", "name": "eNoSC dimethylates histone H3 at lysine-9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10737547" ], "products": [ "species_77502", "species_10732938" ], "modifiers": [ [ "species_10738938", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "O94640", "SPBC16D10.07c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10257", "SPAC56F8.09", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c" ] }, "reaction_10738941": { "compartment": "compartment_7660", "id": "reaction_10738941", "reactome": "R-SPO-427514", "name": "eNoSC deacetylates histone H3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738924", "species_427523" ], "products": [ "species_427498", "species_427497", "species_10737547" ], "modifiers": [ [ "species_10738938", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "O94640", "SPBC16D10.07c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10257", "SPAC56F8.09", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c" ] }, "reaction_10735753": { "compartment": "compartment_7660", "id": "reaction_10735753", "reactome": "R-SPO-176956", "name": "Formation of GINS complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735739", "species_10735734", "species_10735749", "species_10735744" ], "products": [ "species_10735751" ], "modifiers": [], "additional_components": [ "SPBC725.13c", "SPBP23A10.09", "SPBP4H10.21c", "SPAC227.16c", "Q9UTC3", "SPAC227.16c", "O94329", "SPBC725.13c", "Q9P7X6", "SPBP23A10.09", "Q9P7C8", "SPBP4H10.21c" ] }, "reaction_10733255": { "compartment": "compartment_7660", "id": "reaction_10733255", "reactome": "R-SPO-75809", "name": "Phosphorylation of Cdc25C at Ser216 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732945", "species_29358" ], "products": [ "species_113582", "species_10732948" ], "modifiers": [ [ "species_10729617", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC14C4.03" ] }, "reaction_10757028": { "compartment": "compartment_70101", "id": "reaction_10757028", "reactome": "R-SPO-9029987", "name": "p-S216-CDC25C translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732948" ], "products": [ "species_10732952" ], "modifiers": [], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05" ] }, "reaction_10752429": { "compartment": "compartment_984", "id": "reaction_10752429", "reactome": "R-SPO-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752417" ], "products": [ "species_10752427" ], "modifiers": [], "additional_components": [ "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14098", "SPAC2F3.15", "O13864", "SPAC1B1.03c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "P05933", "SPAC3A12.14", "O94395", "SPCC126.02c", "Q9UUJ1", "SPAC11H11.06", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "O14008", "SPAC29A4.05", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "P27638", "SPAC31G5.09c", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "P32834", "SPAC26A3.01", "O74374", "SPBC32F12.10", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O43062", "SPBC4C3.09", "O13907", "SPAC22A12.16", "O94544", "SPCC1322.05c", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13", "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14098", "SPAC2F3.15", "O13864", "SPAC1B1.03c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "P05933", "SPAC3A12.14", "O94395", "SPCC126.02c", "Q9UUJ1", "SPAC11H11.06", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "O14008", "SPAC29A4.05", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "P27638", "SPAC31G5.09c", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "P32834", "SPAC26A3.01", "O74374", "SPBC32F12.10", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O43062", "SPBC4C3.09", "O13907", "SPAC22A12.16", "O94544", "SPCC1322.05c", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13" ] }, "reaction_10752526": { "compartment": "compartment_984", "id": "reaction_10752526", "reactome": "R-SPO-6804099", "name": "HMGB1 binds LTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752522", "species_181015" ], "products": [ "species_10752524" ], "modifiers": [], "additional_components": [ "SPAC57A10.09c", "P87057", "SPAC57A10.09c", "species_181015" ] }, "reaction_10752168": { "compartment": "compartment_6799351", "id": "reaction_10752168", "reactome": "R-SPO-6799350", "name": "Exocytosis of specific granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752152" ], "products": [ "species_10752166" ], "modifiers": [], "additional_components": [ "O13995", "SPAC25B8.01", "Q9P380", "SPBC13A2.04c", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O94296", "SPBC887.12", "Q9HFE5", "SPBP16F5.07", "Q9US20", "SPAC1851.02", "O59826", "SPCC965.06", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O59823", "SPCC965.03", "Q1MTQ5", "SPBC1773.11c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "O59715", "SPBC3B8.07c", "O42901", "SPBC119.09c", "Q09891", "SPAC24B11.12c", "O13995", "SPAC25B8.01", "Q9P380", "SPBC13A2.04c", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O94296", "SPBC887.12", "Q9HFE5", "SPBP16F5.07", "Q9US20", "SPAC1851.02", "O59826", "SPCC965.06", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O59823", "SPCC965.03", "Q1MTQ5", "SPBC1773.11c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "O59715", "SPBC3B8.07c", "O42901", "SPBC119.09c", "Q09891", "SPAC24B11.12c" ] }, "reaction_10741378": { "compartment": "compartment_70101", "id": "reaction_10741378", "reactome": "R-SPO-983156", "name": "Polyubiquitination of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741318", "species_113592", "species_10741312" ], "products": [ "species_10741349", "species_111294", "species_76577", "species_10741310" ], "modifiers": [ [ "species_10741318", "catalyst" ] ], "additional_components": [ "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q09760", "SPAC24H6.03", "P10505", "SPAC17C9.01c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O00102", "SPBP16F5.04", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q09760", "SPAC24H6.03", "P10505", "SPAC17C9.01c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01" ] }, "reaction_10752530": { "compartment": "compartment_984", "id": "reaction_10752530", "reactome": "R-SPO-6804100", "name": "HMGB1 binds LPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752522", "species_166005" ], "products": [ "species_10752528" ], "modifiers": [], "additional_components": [ "SPAC57A10.09c", "P87057", "SPAC57A10.09c", "species_166005" ] }, "reaction_10742867": { "compartment": "compartment_70101", "id": "reaction_10742867", "reactome": "R-SPO-2029456", "name": "RAC1 and CDC42 activate PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738332", "species_10738231" ], "products": [ "species_10742858", "species_10738330" ], "modifiers": [], "additional_components": [ "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "SPBC1604.14c" ] }, "reaction_10752267": { "compartment": "compartment_6800424", "id": "reaction_10752267", "reactome": "R-SPO-6800426", "name": "Exocytosis of ficolin-rich granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752257" ], "products": [ "species_10752265" ], "modifiers": [], "additional_components": [ "P50515", "SPAC1B3.14", "Q9UUF7", "SPBC146.14c", "Q9P3W4", "SPAC458.04c", "Q9Y7J5", "SPBC1778.09", "Q9C0Y4", "SPAPB24D3.10c", "Q09914", "SPAC1F7.04", "O13742", "SPAC16E8.07c", "O13766", "SPAC17A5.04c", "O94323", "SPBC725.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q9C0W7", "SPBC691.03c", "Q9UR05", "SPAC926.07c", "P50515", "SPAC1B3.14", "Q9UUF7", "SPBC146.14c", "Q9P3W4", "SPAC458.04c", "Q9Y7J5", "SPBC1778.09", "Q9C0Y4", "SPAPB24D3.10c", "Q09914", "SPAC1F7.04", "O13742", "SPAC16E8.07c", "O13766", "SPAC17A5.04c", "O94323", "SPBC725.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q9C0W7", "SPBC691.03c", "Q9UR05", "SPAC926.07c" ] }, "reaction_10743526": { "compartment": "compartment_70101", "id": "reaction_10743526", "reactome": "R-SPO-2730835", "name": "Autophosphorylation of PKC-theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10737102" ], "products": [ "species_10743524", "species_29370" ], "modifiers": [], "additional_components": [ "species_112275", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "P36582", "SPAC17G8.14c" ] }, "reaction_10741650": { "compartment": "compartment_70101", "id": "reaction_10741650", "reactome": "R-SPO-1250280", "name": "ROS oxidize thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1250243", "species_10732350" ], "products": [ "species_10732348" ], "modifiers": [], "additional_components": [ "SPBC12D12.07c", "SPBC12D12.07c" ] }, "reaction_10751591": { "compartment": "compartment_6800173", "id": "reaction_10751591", "reactome": "R-SPO-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751567" ], "products": [ "species_10751589" ], "modifiers": [], "additional_components": [ "Q10182", "SPAC3F10.07c", "Q09190", "SPAC1556.04c", "P32834", "SPAC26A3.01", "O74374", "SPBC32F12.10", "O13728", "SPAC15A10.08", "O14254", "SPAC6G10.08", "O94544", "SPCC1322.05c", "Q9P7E8", "SPAPJ760.02c", "O13986", "SPAC26H5.04", "Q10166", "SPAC26A3.11", "Q10182", "SPAC3F10.07c", "P32834", "SPAC26A3.01", "Q09190", "SPAC1556.04c", "O74374", "SPBC32F12.10", "O13728", "SPAC15A10.08", "O14254", "SPAC6G10.08", "O94544", "SPCC1322.05c", "Q9P7E8", "SPAPJ760.02c", "O13986", "SPAC26H5.04", "Q10166", "SPAC26A3.11" ] }, "reaction_10741390": { "compartment": "compartment_17957", "id": "reaction_10741390", "reactome": "R-SPO-983158", "name": "Trimming of peptides in ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983034" ], "products": [ "species_983033", "species_8943716" ], "modifiers": [ [ "species_10741385", "catalyst" ] ], "additional_components": [ "SPBC1921.05" ] }, "reaction_10737119": { "compartment": "compartment_876", "id": "reaction_10737119", "reactome": "R-SPO-202222", "name": "Phosphorylation of PKC theta", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10737102" ], "products": [ "species_29370", "species_10737116" ], "modifiers": [ [ "species_10737090", "catalyst" ] ], "additional_components": [ "species_112275", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "P36582", "SPAC17G8.14c", "species_202247", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10751415": { "compartment": "compartment_6798757", "id": "reaction_10751415", "reactome": "R-SPO-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751383" ], "products": [ "species_10751413" ], "modifiers": [], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q92356", "SPAC6G9.11", "O59866", "SPCC338.15", "O94296", "SPBC887.12", "O60119", "SPBC16G5.05c", "P50515", "SPAC1B3.14", "Q9USS6", "SPBC4.06", "Q9UT43", "SPBC887.12", "Q1MTQ5", "SPBC1773.11c", "Q8TFH3", "SPAPB17E12.11", "P17609", "SPAC9E9.07c", "O74786", "SPBC26H8.02c", "Q9URX4", "SPAC30D11.01c", "O13876", "SPAC1B3.11c", "Q09901", "SPAC30D11.01c", "O74559", "SPCC970.06", "Q9C0Y4", "SPAPB24D3.10c", "Q92356", "SPAC6G9.11", "O59866", "SPCC338.15", "O94296", "SPBC887.12", "O60119", "SPBC16G5.05c", "P50515", "SPAC1B3.14", "Q9USS6", "SPBC4.06", "Q9UT43", "SPBC887.12", "Q1MTQ5", "SPBC1773.11c", "Q8TFH3", "SPAPB17E12.11", "P17609", "SPAC9E9.07c", "O74786", "SPBC26H8.02c", "Q9URX4", "SPAC30D11.01c", "O13876", "SPAC1B3.11c", "Q09901", "SPAC30D11.01c", "O74559", "SPCC970.06" ] }, "reaction_10741351": { "compartment": "compartment_70101", "id": "reaction_10741351", "reactome": "R-SPO-983147", "name": "Release of E3 from polyubiquitinated substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741349" ], "products": [ "species_983123", "species_10741221" ], "modifiers": [], "additional_components": [ "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10743820": { "compartment": "compartment_70101", "id": "reaction_10743820", "reactome": "R-SPO-3204303", "name": "MRE11 binds cytosolic DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_874088", "species_10743816" ], "products": [ "species_10743818" ], "modifiers": [], "additional_components": [ "SPAC13C5.07", "Q09683", "SPAC13C5.07", "species_874088" ] }, "reaction_10745986": { "compartment": "compartment_876", "id": "reaction_10745986", "reactome": "R-SPO-5607734", "name": "PKC-delta translocates to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745398", "species_112275" ], "products": [ "species_10745984" ], "modifiers": [], "additional_components": [ "SPBC12D12.04c", "P36583", "SPBC12D12.04c", "species_112275" ] }, "reaction_10757837": { "compartment": "compartment_70101", "id": "reaction_10757837", "reactome": "R-SPO-9690461", "name": "FKBP1A binds tacrolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757816", "species_9678991" ], "products": [ "species_10757835" ], "modifiers": [], "additional_components": [ "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c", "species_9678991", "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c" ] }, "reaction_10741380": { "compartment": "compartment_70101", "id": "reaction_10741380", "reactome": "R-SPO-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741221", "species_10741312", "species_983035" ], "products": [ "species_10741314" ], "modifiers": [], "additional_components": [ "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O00102", "SPBP16F5.04", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9Y818", "SPBC1105.09", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q9P7R4", "SPBC211.07c", "Q09760", "SPAC24H6.03", "P23566", "SPAC18B11.07c", "P10505", "SPAC17C9.01c", "O00103", "SPCC1259.15c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O00102", "SPBP16F5.04", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "O74983", "SPCC338.05c", "Q09855", "SPAC29E6.01", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O94609", "SPBC1604.21c", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q9UTN8", "SPAC1250.03", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "O42646", "SPAC10F6.05c", "Q9P4W7", "SPAC959.09c", "O74549", "SPCC777.10c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01" ] }, "reaction_10751953": { "compartment": "compartment_1462052", "id": "reaction_10751953", "reactome": "R-SPO-6798748", "name": "Exocytosis of secretory granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751817" ], "products": [ "species_10751951" ], "modifiers": [], "additional_components": [ "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "O42842", "SPAC23A1.03", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "Q9HGM8", "SPBC543.03c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "O14242", "SPAC6F6.11c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "O94395", "SPCC126.02c", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O74335", "SPBC17F3.01c", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O94466", "SPBC23G7.08c", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "Q10305", "SPAC22H10.12c", "O43062", "SPBC4C3.09", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13", "O13808", "SPAC17H9.11", "O13370", "SPCC1795.11", "O42938", "SPBC16H5.02", "Q9UTG1", "SPAC1805.16c", "O74478", "SPCC1840.05c", "O42842", "SPAC23A1.03", "Q10316", "SPAC17G8.04c", "P87057", "SPAC57A10.09c", "P0CT53", "SPCC794.09c", "O13834", "SPAC19D5.04", "P50998", "SPBC106.04", "Q9P7Q8", "SPAC1834.06c", "O14126", "SPAC3A11.12c", "O14256", "SPAC6G10.10c", "Q9HGM8", "SPBC543.03c", "P0CU18", "SPAPB8E5.02c", "P41887", "SPAC926.04c", "O14242", "SPAC6F6.11c", "P50521", "SPAC4F8.07c", "Q09841", "SPAC23D3.07", "P78917", "SPBC1604.05", "P55306", "SPCC757.07c", "P0CU17", "SPAC1420.03", "P78974", "SPAC1805.06c", "P40232", "SPAC1851.03", "Q09190", "SPAC1556.04c", "O94395", "SPCC126.02c", "O14254", "SPAC6G10.08", "Q09892", "SPAC24B11.06c", "P0CT55", "SPBC839.15c", "P78921", "SPBC337.05c", "O43061", "SPBC4C3.08", "Q9UT97", "SPAC323.02c", "Q10335", "SPBC582.07c", "P87048", "SPBP19A11.03c", "Q9UTS6", "SPAC1805.08", "P0CT54", "SPAC23A1.10", "Q9US13", "SPAC607.05", "O43069", "SPBC6B1.05c", "Q9P7S2", "SPAC23G3.11", "Q09756", "SPAC24H6.04", "Q09680", "SPBC4C3.09", "Q10208", "SPAC4H3.10c", "O42897", "SPBC119.01", "O74335", "SPBC17F3.01c", "O14344", "SPBC2F12.14c", "P49740", "SPAC806.07", "O94466", "SPBC23G7.08c", "O42931", "SPBC16C6.07c", "Q10265", "SPAC13G7.02c", "Q9P7E8", "SPAPJ760.02c", "P36623", "SPAC26F1.06", "Q9P372", "SPAC19B12.09", "O94579", "SPCC1442.06", "Q9P3A8", "SPAC1565.07c", "Q9P3A7", "SPAC1565.08", "O14460", "SPAC513.01c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "Q10305", "SPAC22H10.12c", "O43062", "SPBC4C3.09", "O74887", "SPCC576.03c", "O94630", "SPBC1347.12", "P41878", "SPAC31G5.13" ] }, "reaction_10738399": { "compartment": "compartment_70101", "id": "reaction_10738399", "reactome": "R-SPO-390329", "name": "Dephosphorylation of AKT by PP2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736505", "species_29356" ], "products": [ "species_10738396", "species_29372" ], "modifiers": [ [ "species_10738274", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10428", "SPCC188.02", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "P78759", "SPAC6F12.12" ] }, "reaction_10741612": { "compartment": "compartment_70101", "id": "reaction_10741612", "reactome": "R-SPO-1247960", "name": "Activation of p38 MAPK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741601" ], "products": [ "species_29370", "species_10741609" ], "modifiers": [ [ "species_10739738", "catalyst" ] ], "additional_components": [ "Q09892", "SPAC24B11.06c", "Q09892", "SPAC24B11.06c", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c" ] }, "reaction_10741353": { "compartment": "compartment_70101", "id": "reaction_10741353", "reactome": "R-SPO-983150", "name": "Proteasomal cleavage of substrate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983123" ], "products": [ "species_983032", "species_983036", "species_10729165", "species_8942986" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10742956": { "compartment": "compartment_161320", "id": "reaction_10742956", "reactome": "R-SPO-2130706", "name": "MHC class II antigen processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2213225" ], "products": [ "species_2213226" ], "modifiers": [ [ "species_10742951", "catalyst" ] ], "additional_components": [ "SPAC26A3.01" ] }, "reaction_10751977": { "compartment": "compartment_6799371", "id": "reaction_10751977", "reactome": "R-SPO-6798749", "name": "Exocytosis of specific granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751969" ], "products": [ "species_10751975" ], "modifiers": [], "additional_components": [ "P32834", "SPAC26A3.01", "O14242", "SPAC6F6.11c", "O13728", "SPAC15A10.08", "Q10166", "SPAC26A3.11", "O13864", "SPAC1B1.03c", "O13986", "SPAC26H5.04", "Q10066", "SPAC3H1.07", "P32834", "SPAC26A3.01", "O13728", "SPAC15A10.08", "O14242", "SPAC6F6.11c", "O13986", "SPAC26H5.04", "Q10166", "SPAC26A3.11", "O13864", "SPAC1B1.03c", "Q10066", "SPAC3H1.07" ] }, "reaction_10751653": { "compartment": "compartment_6799713", "id": "reaction_10751653", "reactome": "R-SPO-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751641" ], "products": [ "species_10751651" ], "modifiers": [], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q09706", "SPAC2F7.16c", "Q92356", "SPAC6G9.11", "O94296", "SPBC887.12", "Q9UR05", "SPAC926.07c", "P50515", "SPAC1B3.14", "O59826", "SPCC965.06", "Q9UUF7", "SPBC146.14c", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q09891", "SPAC24B11.12c", "Q9C0Y4", "SPAPB24D3.10c", "Q09706", "SPAC2F7.16c", "Q92356", "SPAC6G9.11", "O94296", "SPBC887.12", "Q9UR05", "SPAC926.07c", "P50515", "SPAC1B3.14", "O59826", "SPCC965.06", "Q9UUF7", "SPBC146.14c", "Q9UT43", "SPBC887.12", "O36028", "SPAC4F10.16c", "O13766", "SPAC17A5.04c", "O74786", "SPBC26H8.02c", "Q9Y7J2", "SPBC1778.05c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c", "Q09891", "SPAC24B11.12c" ] }, "reaction_10745990": { "compartment": "compartment_876", "id": "reaction_10745990", "reactome": "R-SPO-5607746", "name": "PKC-delta is activated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745984" ], "products": [ "species_10745988" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "species_112275", "P36583", "SPBC12D12.04c", "species_112275" ] }, "reaction_10741530": { "compartment": "compartment_1222693", "id": "reaction_10741530", "reactome": "R-SPO-1222516", "name": "Intraphagosomal pH is lowered to 5 by V-ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106" ], "products": [ "species_1470067" ], "modifiers": [ [ "species_10741527", "catalyst" ] ], "additional_components": [ "P50515", "SPAC1B3.14", "O43046", "SPBC3B9.18c", "O14265", "SPAC7D4.10", "O74174", "SPBC1289.05c", "O59823", "SPCC965.03", "O14046", "SPAC2C4.13", "O13742", "SPAC16E8.07c", "P31406", "SPAC343.05", "P31411", "SPAC637.05c", "O13753", "SPAC17A2.03c", "O13687", "SPAC11E3.07", "Q69Z14", "SPBC1685.16", "Q9HDW6", "SPAPB2B4.05" ] }, "reaction_10741321": { "compartment": "compartment_70101", "id": "reaction_10741321", "reactome": "R-SPO-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10741314" ], "products": [ "species_10741318", "species_111294", "species_76577", "species_10741310" ], "modifiers": [ [ "species_10741221", "catalyst" ] ], "additional_components": [ "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9Y818", "SPBC1105.09", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q9P7R4", "SPBC211.07c", "Q09760", "SPAC24H6.03", "P23566", "SPAC18B11.07c", "P10505", "SPAC17C9.01c", "O00103", "SPCC1259.15c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O00102", "SPBP16F5.04", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "O74983", "SPCC338.05c", "Q09855", "SPAC29E6.01", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O94609", "SPBC1604.21c", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q9UTN8", "SPAC1250.03", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "O42646", "SPAC10F6.05c", "Q9P4W7", "SPAC959.09c", "O74549", "SPCC777.10c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "Q09838", "SPAC4G8.13c", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "P78972", "SPAC821.08c", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O60106", "SPBC14F5.10c", "P0CH07", "SPAC1805.12c", "O13286", "SPAC144.13c", "P0C016", "SPAC6G10.11c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O14326", "SPBC16E9.11c", "Q09760", "SPAC24H6.03", "P10505", "SPAC17C9.01c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "P36630", "SPAPB2B4.03", "O14212", "SPBC14F5.10c", "Q9UT72", "SPAC343.18", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "Q9UTL5", "SPAC144.09c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "O42971", "SPBC1A4.01", "O13731", "SPAC15A10.11", "O43125", "SPBC119.05c", "P41889", "SPAC6F12.15c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9US46", "SPAC1002.14", "O13834", "SPAC19D5.04", "Q9USX9", "SPBC1861.07", "O14212", "SPBC14F5.10c", "P78972", "SPAC821.08c", "Q9UT72", "SPAC343.18", "Q9UT86", "SPAC343.03", "Q92462", "SPAC11G7.02", "O94294", "SPBC887.09c", "O74349", "SPBC21D10.09c", "O60106", "SPBC14F5.10c", "O94289", "SPBC887.04c", "O13286", "SPAC144.13c", "O74531", "SPCC1827.08c", "O94556", "SPAC6F12.14", "Q9HE05", "SPAC20H4.10", "Q10435", "SPAC12B10.01c", "P41000", "SPAC3A11.02", "O14326", "SPBC16E9.11c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "P10505", "SPAC17C9.01c", "O94264", "SPBP8B7.15c", "Q9P4W7", "SPAC959.09c", "O42839", "SPAC19G12.01c", "Q9URV2", "SPBC106.09", "O74855", "SPCC18.05c", "Q874R3", "SPBP23A10.04", "Q1K9C4", "SPAC167.07c", "Q9P3U4", "SPAC328.02", "O74751", "SPBC1734.10c", "P10815", "SPBC582.03", "O60152", "SPBC19C7.02", "Q10311", "SPAC6C3.08", "Q9UTG2", "SPAC1805.15c", "O74463", "SPCC1739.01", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10740329": { "compartment": "compartment_70101", "id": "reaction_10740329", "reactome": "R-SPO-874087", "name": "SGT1 binds HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740325", "species_10740323" ], "products": [ "species_10740327" ], "modifiers": [], "additional_components": [ "SPAC926.04c", "SPBC36.12c", "P41887", "SPAC926.04c", "O59709", "SPBC36.12c" ] }, "reaction_10741337": { "compartment": "compartment_17957", "id": "reaction_10741337", "reactome": "R-SPO-983144", "name": "Transport of Antigen peptide in to ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983032", "species_113592", "species_29356" ], "products": [ "species_983034", "species_29370", "species_29372" ], "modifiers": [ [ "species_10741334", "catalyst" ] ], "additional_components": [ "P78966", "SPBC25B2.02c" ] }, "reaction_10742881": { "compartment": "compartment_876", "id": "reaction_10742881", "reactome": "R-SPO-2029471", "name": "Hydrolysis of PC to PA by PLD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429802", "species_29356" ], "products": [ "species_264618", "species_1602448" ], "modifiers": [ [ "species_10742876", "catalyst" ] ], "additional_components": [ "SPAC2F7.16c" ] }, "reaction_10737092": { "compartment": "compartment_70101", "id": "reaction_10737092", "reactome": "R-SPO-202164", "name": "Translocation of PDK1 to Plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737088", "species_202277" ], "products": [ "species_10737090" ], "modifiers": [], "additional_components": [ "SPCC576.15c", "species_202247", "species_179838", "species_202247", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10752099": { "compartment": "compartment_1470028", "id": "reaction_10752099", "reactome": "R-SPO-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752055" ], "products": [ "species_10752097" ], "modifiers": [], "additional_components": [ "Q9UT70", "SPAC3G9.16c", "O74762", "SPBC17D11.07c", "O74557", "SPCC970.03", "Q9UUJ1", "SPAC11H11.06", "Q9P3A7", "SPAC1565.08", "P27638", "SPAC31G5.09c", "P05219", "SPBC26H8.07c", "O74490", "SPCC1442.17c", "O74492", "SPCC285.04", "Q9URZ0", "SPAC869.07c", "P78921", "SPBC337.05c", "Q10305", "SPAC22H10.12c", "O74498", "SPCC285.11", "P36621", "SPCC306.09c", "O74335", "SPBC17F3.01c", "O13907", "SPAC22A12.16", "P36583", "SPBC12D12.04c", "O14344", "SPBC2F12.14c", "P15258", "SPBC21.05c", "Q10147", "SPAC1D4.04", "O13290", "SPAC1093.06c", "Q09184", "SPAC23H4.09", "Q10066", "SPAC3H1.07", "Q9UUB5", "SPBC409.09c", "Q9UT70", "SPAC3G9.16c", "O74762", "SPBC17D11.07c", "O74557", "SPCC970.03", "Q9UUJ1", "SPAC11H11.06", "Q9P3A7", "SPAC1565.08", "P27638", "SPAC31G5.09c", "P05219", "SPBC26H8.07c", "O74490", "SPCC1442.17c", "O74492", "SPCC285.04", "Q9URZ0", "SPAC869.07c", "P78921", "SPBC337.05c", "Q10305", "SPAC22H10.12c", "O74498", "SPCC285.11", "P36621", "SPCC306.09c", "O74335", "SPBC17F3.01c", "O13907", "SPAC22A12.16", "P36583", "SPBC12D12.04c", "O14344", "SPBC2F12.14c", "P15258", "SPBC21.05c", "Q10147", "SPAC1D4.04", "O13290", "SPAC1093.06c", "Q09184", "SPAC23H4.09", "Q10066", "SPAC3H1.07", "Q9UUB5", "SPBC409.09c" ] }, "reaction_10741648": { "compartment": "compartment_70101", "id": "reaction_10741648", "reactome": "R-SPO-1250264", "name": "TXNIP binds reduced thioredoxin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741644", "species_10732350" ], "products": [ "species_10741646" ], "modifiers": [], "additional_components": [ "Q09889", "SPCC584.15c", "O60150", "SPCC584.15c", "Q8WZK5", "SPCC584.15c", "Q10347", "SPCC584.15c", "Q09729", "SPCC584.15c", "O74798", "SPCC584.15c", "SPBC12D12.07c", "Q09889", "SPCC584.15c", "O60150", "SPCC584.15c", "Q8WZK5", "SPCC584.15c", "Q10347", "SPCC584.15c", "Q09729", "SPCC584.15c", "O94504", "SPBC12D12.07c", "O74798", "SPCC584.15c" ] }, "reaction_10742887": { "compartment": "compartment_70101", "id": "reaction_10742887", "reactome": "R-SPO-2029473", "name": "Branching and elongation of mother and daughter filaments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737182", "species_10742885" ], "products": [ "species_10742765" ], "modifiers": [], "additional_components": [ "species_113592", "O60054", "SPBC56F2.03", "P10989", "SPBC32H8.12c", "P78774", "SPBC14C8.06", "Q10316", "SPAC17G8.04c", "Q9UUJ1", "SPAC11H11.06", "Q92352", "SPAC6G9.07c", "O60054", "SPBC56F2.03", "species_29370", "species_113592", "O14241", "SPAC6F6.10c", "P32390", "SPAC630.03", "Q9Y7J4", "SPBC1778.08c", "P10989", "SPBC32H8.12c", "P78774", "SPBC14C8.06", "Q10316", "SPAC17G8.04c", "Q9UUJ1", "SPAC11H11.06", "Q92352", "SPAC6G9.07c", "O14241", "SPAC6F6.10c", "species_113592", "O60054", "SPBC56F2.03", "P32390", "SPAC630.03", "Q9Y7J4", "SPBC1778.08c", "P10989", "SPBC32H8.12c" ] }, "reaction_10742865": { "compartment": "compartment_70101", "id": "reaction_10742865", "reactome": "R-SPO-2029454", "name": "Autophosphorylation of PAK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742858", "species_113592" ], "products": [ "species_29370", "species_10742862", "species_10738231" ], "modifiers": [ [ "species_10738330", "catalyst" ] ], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "SPBC1604.14c" ] }, "reaction_10741375": { "compartment": "compartment_70101", "id": "reaction_10741375", "reactome": "R-SPO-983153", "name": "E1 mediated ubiquitin activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10729165", "species_29926", "species_10741367" ], "products": [ "species_10741369", "species_111294", "species_76577", "species_29926" ], "modifiers": [ [ "species_10741367", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O43069", "SPBC6B1.05c", "Q09765", "SPAC24H6.12c", "O94609", "SPBC1604.21c", "O43069", "SPBC6B1.05c", "P0CH07", "SPAC1805.12c", "Q09765", "SPAC24H6.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O43069", "SPBC6B1.05c", "Q09765", "SPAC24H6.12c", "O94609", "SPBC1604.21c" ] }, "reaction_10738619": { "compartment": "compartment_70101", "id": "reaction_10738619", "reactome": "R-SPO-418436", "name": "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10738616", "catalyst" ] ], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01" ] }, "reaction_10743556": { "compartment": "compartment_70101", "id": "reaction_10743556", "reactome": "R-SPO-2730867", "name": "Translocation of CaN:CaM:NFAT to nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743536" ], "products": [ "species_10743554" ], "modifiers": [], "additional_components": [ "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q12705", "SPBP4H10.04", "CHEBI:29034", "species_442320", "Q9UU93", "SPCC830.06", "P05933", "SPAC3A12.14", "species_74016", "Q12705", "SPBP4H10.04", "O14008", "SPAC29A4.05", "CHEBI:29034" ] }, "reaction_10737443": { "compartment": "compartment_12045", "id": "reaction_10737443", "reactome": "R-SPO-203979", "name": "Coat Assembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737349", "species_10737439" ], "products": [ "species_10737441" ], "modifiers": [], "additional_components": [ "Q01475", "SPBC31F10.06c", "species_29438", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q01475", "SPBC31F10.06c", "Q9USS7", "SPBC4.03c", "species_29438" ] }, "reaction_10741491": { "compartment": "compartment_70101", "id": "reaction_10741491", "reactome": "R-SPO-1168373", "name": "PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734514", "species_74016", "species_33625", "species_114519" ], "products": [ "species_10734538" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10751533": { "compartment": "compartment_876", "id": "reaction_10751533", "reactome": "R-SPO-6798743", "name": "Exocytosis of secretory granule membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751485" ], "products": [ "species_10751531" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "Q9HDY0", "SPAPB1A10.10c", "Q9P3W4", "SPAC458.04c", "Q09914", "SPAC1F7.04", "Q10133", "SPAC16.01", "P17608", "SPAC4C5.02c", "Q9C0W7", "SPBC691.03c", "Q9HE04", "SPAC20H4.11c", "O94655", "SPBC405.04c", "Q9UUF7", "SPBC146.14c", "Q9USX1", "SPBC1921.05", "O13742", "SPAC16E8.07c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "O42901", "SPBC119.09c", "Q10201", "SPBC17D1.07c", "Q9HDY0", "SPAPB1A10.10c", "Q9P3W4", "SPAC458.04c", "Q09914", "SPAC1F7.04", "Q10133", "SPAC16.01", "P17608", "SPAC4C5.02c", "Q9C0W7", "SPBC691.03c", "Q9HE04", "SPAC20H4.11c", "O94655", "SPBC405.04c", "Q9UUF7", "SPBC146.14c", "Q9USX1", "SPBC1921.05", "O13742", "SPAC16E8.07c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "O42901", "SPBC119.09c" ] }, "reaction_10742874": { "compartment": "compartment_876", "id": "reaction_10742874", "reactome": "R-SPO-2029468", "name": "Conversion of PA into DAG by PAP-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_29372", "species_112275" ], "modifiers": [ [ "species_10742869", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10737129": { "compartment": "compartment_70101", "id": "reaction_10737129", "reactome": "R-SPO-202328", "name": "Translocation of PKC theta to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736928", "species_112275" ], "products": [ "species_10737127" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "P36582", "SPAC17G8.14c" ] }, "reaction_10741395": { "compartment": "compartment_70101", "id": "reaction_10741395", "reactome": "R-SPO-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_983036" ], "products": [ "species_983032", "species_8942986" ], "modifiers": [ [ "species_10741392", "catalyst" ] ], "additional_components": [ "SPBC1921.05" ] }, "reaction_10741372": { "compartment": "compartment_70101", "id": "reaction_10741372", "reactome": "R-SPO-983152", "name": "Transfer of ubiquitin from E1 to E2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741369", "species_10741310" ], "products": [ "species_10741312", "species_10741367" ], "modifiers": [ [ "species_10741310", "catalyst" ] ], "additional_components": [ "O43069", "SPBC6B1.05c", "P0CH07", "SPAC1805.12c", "Q09765", "SPAC24H6.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O00102", "SPBP16F5.04", "O74810", "SPBC2D10.20", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "O43069", "SPBC6B1.05c", "Q09765", "SPAC24H6.12c", "O94609", "SPBC1604.21c", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P23566", "SPAC18B11.07c", "O94609", "SPBC1604.21c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "O42646", "SPAC10F6.05c", "O74549", "SPCC777.10c", "O74983", "SPCC338.05c", "Q9UTN8", "SPAC1250.03", "O13685", "SPAC11E3.04c", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04" ] }, "reaction_10745417": { "compartment": "compartment_70101", "id": "reaction_10745417", "reactome": "R-SPO-5218813", "name": "DAG and Ca+2 bind to PKC and tether it to membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745410", "species_74016", "species_112275" ], "products": [ "species_10745415" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "species_112275", "species_74016", "P36582", "SPAC17G8.14c" ] }, "reaction_10737056": { "compartment": "compartment_70101", "id": "reaction_10737056", "reactome": "R-SPO-202127", "name": "eNOS synthesizes NO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29468", "species_29368" ], "products": [ "species_29366", "species_202124", "species_29968" ], "modifiers": [ [ "species_10737053", "catalyst" ], [ "species_5693375", "inhibitor" ] ], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "P36587", "SPBC29A10.01", "species_29870" ] }, "reaction_10737080": { "compartment": "compartment_70101", "id": "reaction_10737080", "reactome": "R-SPO-202137", "name": "AKT1 binds eNOS complex via HSP90", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737016", "species_10736495" ], "products": [ "species_10737024" ], "modifiers": [], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "P41887", "SPAC926.04c", "species_74016", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "O14008", "SPAC29A4.05", "P36587", "SPBC29A10.01", "species_113596", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "species_442320", "Q10364", "SPAC22E12.14c", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "P41887", "SPAC926.04c", "species_74016", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "O14008", "SPAC29A4.05", "P36587", "SPBC29A10.01", "P50530", "SPAC1B9.02c", "species_113596" ] }, "reaction_10745428": { "compartment": "compartment_876", "id": "reaction_10745428", "reactome": "R-SPO-5218821", "name": "PDK1 phosphorylates PKC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10745425" ], "products": [ "species_29370", "species_10745378" ], "modifiers": [ [ "species_10733716", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "SPCC576.15c" ] }, "reaction_10737051": { "compartment": "compartment_70101", "id": "reaction_10737051", "reactome": "R-SPO-202111", "name": "AKT1 phosphorylates eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10737024" ], "products": [ "species_29370", "species_10737049" ], "modifiers": [], "additional_components": [ "species_442320", "Q10364", "SPAC22E12.14c", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "P41887", "SPAC926.04c", "species_74016", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "O14008", "SPAC29A4.05", "P36587", "SPBC29A10.01", "P50530", "SPAC1B9.02c", "species_113596", "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_29870", "P36587", "SPBC29A10.01" ] }, "reaction_10742175": { "compartment": "compartment_70101", "id": "reaction_10742175", "reactome": "R-SPO-1497784", "name": "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29870", "species_10737049" ], "products": [ "species_10737053" ], "modifiers": [], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_29870", "P36587", "SPBC29A10.01", "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "P36587", "SPBC29A10.01", "species_29870" ] }, "reaction_10745434": { "compartment": "compartment_876", "id": "reaction_10745434", "reactome": "R-SPO-5218823", "name": "PKC phosphorylates sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738404", "species_113592" ], "products": [ "species_29370", "species_10745431" ], "modifiers": [ [ "species_10745415", "catalyst" ] ], "additional_components": [ "SPAC4A8.07c", "SPAC4A8.07c", "P36583", "SPBC12D12.04c", "species_112275", "species_74016", "P36582", "SPAC17G8.14c" ] }, "reaction_10745413": { "compartment": "compartment_70101", "id": "reaction_10745413", "reactome": "R-SPO-5218805", "name": "PKC autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745378", "species_113592" ], "products": [ "species_29370", "species_10745410" ], "modifiers": [ [ "species_10745378", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10756127": { "compartment": "compartment_70616", "id": "reaction_10756127", "reactome": "R-SPO-8949580", "name": "F1Fo ATP synthase dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735134" ], "products": [ "species_10756125" ], "modifiers": [], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10743814": { "compartment": "compartment_7660", "id": "reaction_10743814", "reactome": "R-SPO-3108212", "name": "SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743242", "species_10743647" ], "products": [ "species_10743639", "species_10743780" ], "modifiers": [ [ "species_10743811", "catalyst" ] ], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "Q92380", "SPCC4E9.01c", "O13351", "SPBC365.06", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "P53692", "SPCC5E4.06", "O13710", "SPAC14C4.02c", "Q6BDR8", "SPBC20F10.04c", "Q4PIR3", "SPAC16A10.06c", "Q9Y7U4", "SPCC645.04", "Q53EK2", "SPCC550.05" ] }, "reaction_10744821": { "compartment": "compartment_7660", "id": "reaction_10744821", "reactome": "R-SPO-4551648", "name": "SUMOylation of TDG with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10733857" ], "products": [ "species_10743639", "species_10744819" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPCC965.05c", "SPAC30D11.13", "O13351", "SPBC365.06", "O59825", "SPCC965.05c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744848": { "compartment": "compartment_7660", "id": "reaction_10744848", "reactome": "R-SPO-4568863", "name": "SUMOylation of RAD52 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733420", "species_10743647" ], "products": [ "species_10743639", "species_10744846" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC30D11.10", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P36592", "SPAC30D11.10", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744919": { "compartment": "compartment_7660", "id": "reaction_10744919", "reactome": "R-SPO-4570554", "name": "SUMOylation of MDC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744909", "species_10743647" ], "products": [ "species_10743639", "species_10744917" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPACUNK4.14", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O14079", "SPACUNK4.14", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744904": { "compartment": "compartment_7660", "id": "reaction_10744904", "reactome": "R-SPO-4570528", "name": "SUMOylation of XPC with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744894", "species_10743647" ], "products": [ "species_10743639", "species_10744902" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPCC4G3.10c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P87235", "SPCC4G3.10c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10730240": { "compartment": "compartment_70101", "id": "reaction_10730240", "reactome": "R-SPO-71286", "name": "guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_30401" ], "products": [ "species_70106", "species_71285", "species_29916" ], "modifiers": [ [ "species_10730237", "catalyst" ] ], "additional_components": [ "SPAC26A3.17c" ] }, "reaction_10753723": { "compartment": "compartment_12045", "id": "reaction_10753723", "reactome": "R-SPO-8848582", "name": "AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8848577", "species_200993" ], "products": [ "species_76194", "species_8848499" ], "modifiers": [ [ "species_10749964", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10753726": { "compartment": "compartment_12045", "id": "reaction_10753726", "reactome": "R-SPO-8848585", "name": "AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30209", "species_200993" ], "products": [ "species_76194", "species_2534407" ], "modifiers": [ [ "species_10749964", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10749962": { "compartment": "compartment_12045", "id": "reaction_10749962", "reactome": "R-SPO-5696424", "name": "AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696426", "species_192172" ], "products": [ "species_162743", "species_5696412" ], "modifiers": [ [ "species_10749959", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10734474": { "compartment": "compartment_7660", "id": "reaction_10734474", "reactome": "R-SPO-113504", "name": "Detection of damage during initiation of DNA synthesis in S-phase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729371" ], "products": [ "species_113656", "species_10728742" ], "modifiers": [], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c" ] }, "reaction_10756722": { "compartment": "compartment_70101", "id": "reaction_10756722", "reactome": "R-SPO-9013024", "name": "RHOB binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756718", "species_10756713" ], "products": [ "species_10756720" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "P36583", "SPBC12D12.04c", "P78953", "SPCC4B3.15", "Q92356", "SPAC6G9.11", "O14188", "SPAC4F8.13c", "O74786", "SPBC26H8.02c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "O43027", "SPBC354.13", "Q10133", "SPAC16.01", "species_29438", "Q9P3B1", "SPAC1565.02c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "O74786", "SPBC26H8.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c" ] }, "reaction_10756711": { "compartment": "compartment_70101", "id": "reaction_10756711", "reactome": "R-SPO-9013021", "name": "GDIs block activation of RHOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756705", "species_10756703" ], "products": [ "species_10756709" ], "modifiers": [], "additional_components": [ "SPAC6F12.06", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O14224", "SPAC6F12.06" ] }, "reaction_10756716": { "compartment": "compartment_70101", "id": "reaction_10756716", "reactome": "R-SPO-9013022", "name": "RHOB GAPs stimulate RHOB GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756713", "species_29356" ], "products": [ "species_29372", "species_10756703" ], "modifiers": [ [ "species_10756508", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757839": { "compartment": "compartment_876", "id": "reaction_10757839", "reactome": "R-SPO-9690494", "name": "RHOB translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756713" ], "products": [ "species_10746731" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10737802": { "compartment": "compartment_70101", "id": "reaction_10737802", "reactome": "R-SPO-350598", "name": "Arginine<=>Agmatine+CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468" ], "products": [ "species_113528", "species_351164" ], "modifiers": [ [ "species_10737799", "catalyst" ] ], "additional_components": [ "SPAC144.04c" ] }, "reaction_10740399": { "compartment": "compartment_5460", "id": "reaction_10740399", "reactome": "R-SPO-916855", "name": "PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_916850" ], "products": [ "species_113552", "species_880046" ], "modifiers": [ [ "species_10740396", "catalyst" ] ], "additional_components": [ "CHEBI:33739", "O13837", "SPAC19D5.07" ] }, "reaction_10740363": { "compartment": "compartment_5460", "id": "reaction_10740363", "reactome": "R-SPO-888548", "name": "ALDH5A1 dehydrogenates SUCCSA to SUCCA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_880046", "species_113526" ], "products": [ "species_113536", "species_29362", "species_113529" ], "modifiers": [ [ "species_10740360", "catalyst" ] ], "additional_components": [ "Q9US47", "SPAC1002.12c" ] }, "reaction_10735650": { "compartment": "compartment_7660", "id": "reaction_10735650", "reactome": "R-SPO-174451", "name": "Recruitment of DNA2 endonuclease to the C strand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735624", "species_10729513" ], "products": [ "species_10735626" ], "modifiers": [], "additional_components": [ "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "O14246", "SPAC6F6.16c", "Q96TL7", "SPBC1778.02", "P87324", "SPAC27E2.05", "CHEBI:15986", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "O13988", "SPAC26H5.06", "Q92372", "SPBC660.13c", "SPBC16D10.04c", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "O14246", "SPAC6F6.16c", "Q96TL7", "SPBC1778.02", "P87324", "SPAC27E2.05", "Q9URU2", "SPBC16D10.04c", "CHEBI:15986", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "O13988", "SPAC26H5.06", "Q92372", "SPBC660.13c" ] }, "reaction_10732942": { "compartment": "compartment_350", "id": "reaction_10732942", "reactome": "R-SPO-74986", "name": "Elongation of pre-rRNA transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_74985" ], "products": [ "species_74985" ], "modifiers": [ [ "species_10732500", "catalyst" ], [ "species_10732940", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "O94703", "SPCC1259.03", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O14086", "SPAC2F3.03c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "Q9UST5", "SPBC336.09c", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "Q9P7X8", "SPBP23A10.07", "O74366", "SPBC30B4.07c", "O43036", "SPBC3B9.07c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P40381", "SPAC664.01c", "P04909", "SPCC622.08c", "Q10103", "SPAC18G6.02c", "O42934", "SPBC16C6.10" ] }, "reaction_10732415": { "compartment": "compartment_7660", "id": "reaction_10732415", "reactome": "R-SPO-73757", "name": "Binding of RRN3 to RNA Polymerase I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732406", "species_10732411" ], "products": [ "species_10732413" ], "modifiers": [], "additional_components": [ "O94703", "SPCC1259.03", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "O94616", "SPBC1289.07c", "O14086", "SPAC2F3.03c", "Q92399", "SPBC14C8.12", "Q9P7X8", "SPBP23A10.07", "O13877", "SPAC1B3.12c", "O43036", "SPBC3B9.07c", "SPAC18G6.11c", "O94703", "SPCC1259.03", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P15398", "SPBC4C3.05c", "Q10110", "SPAC18G6.11c", "P48011", "SPBC19C2.03", "O94616", "SPBC1289.07c", "O14086", "SPAC2F3.03c", "Q92399", "SPBC14C8.12", "Q9P7X8", "SPBP23A10.07", "O13877", "SPAC1B3.12c", "O43036", "SPBC3B9.07c" ] }, "reaction_10732502": { "compartment": "compartment_7660", "id": "reaction_10732502", "reactome": "R-SPO-73769", "name": "Loss of Rrn3 from RNA Polymerase I promoter escape complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732496" ], "products": [ "species_10732411", "species_10732500" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "O94703", "SPCC1259.03", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "Q10110", "SPAC18G6.11c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O14086", "SPAC2F3.03c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "Q9UST5", "SPBC336.09c", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "Q9P7X8", "SPBP23A10.07", "O74366", "SPBC30B4.07c", "O43036", "SPBC3B9.07c", "SPAC18G6.11c", "P36613", "SPBP16F5.02", "O94703", "SPCC1259.03", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94616", "SPBC1289.07c", "P17871", "SPAC3A11.12c", "O14086", "SPAC2F3.03c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "Q9UST5", "SPBC336.09c", "P15398", "SPBC4C3.05c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "Q9P7X8", "SPBP23A10.07", "O74366", "SPBC30B4.07c", "O43036", "SPBC3B9.07c" ] }, "reaction_10739704": { "compartment": "compartment_5460", "id": "reaction_10739704", "reactome": "R-SPO-449937", "name": "pyrophosphate + H2O => 2 orthophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_159450" ], "products": [ "species_113548" ], "modifiers": [ [ "species_10739701", "catalyst" ], [ "species_109496", "catalyst" ] ], "additional_components": [ "P19117", "SPAC23C11.05" ] }, "reaction_10735146": { "compartment": "compartment_5460", "id": "reaction_10735146", "reactome": "R-SPO-164840", "name": "ADP and Pi bind to ATPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_10735134", "species_113581" ], "products": [ "species_10735136" ], "modifiers": [], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "species_29370", "Q09774", "SPAC22F3.07c", "species_29372", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10735144": { "compartment": "compartment_5460", "id": "reaction_10735144", "reactome": "R-SPO-164834", "name": "Enzyme-bound ATP is released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735138", "species_163953" ], "products": [ "species_10735134", "species_113529", "species_113593" ], "modifiers": [ [ "species_10735138", "catalyst" ] ], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "species_113592", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "species_113592", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10735141": { "compartment": "compartment_5460", "id": "reaction_10735141", "reactome": "R-SPO-164832", "name": "ATPase synthesizes ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735136" ], "products": [ "species_10735138", "species_113521" ], "modifiers": [ [ "species_10735136", "catalyst" ] ], "additional_components": [ "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "species_29370", "Q09774", "SPAC22F3.07c", "species_29372", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "Q09774", "SPAC22F3.07c", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "species_113592", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11", "P21535", "SPMIT.07", "O74999", "SPCC330.02", "P22068", "SPAC222.12c", "P87316", "SPBC31F10.15c", "species_29370", "Q09774", "SPAC22F3.07c", "species_29372", "O94390", "SPBC29A10.13", "Q9P6R6", "SPBC13E7.04", "O74479", "SPCC1840.06", "P21537", "SPMIT.10", "O74754", "SPBC1734.13", "P24487", "SPAC14C4.14", "O94373", "SPBC1604.07", "O74783", "SPBC25B2.11" ] }, "reaction_10756939": { "compartment": "compartment_876", "id": "reaction_10756939", "reactome": "R-SPO-9018798", "name": "RHOV binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756937" ], "products": [ "species_10756922", "species_29420" ], "modifiers": [], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "Q01112", "SPAC110.03", "species_29438" ] }, "reaction_10756935": { "compartment": "compartment_876", "id": "reaction_10756935", "reactome": "R-SPO-9018794", "name": "RHOV binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756931", "species_10756922" ], "products": [ "species_10756933" ], "modifiers": [], "additional_components": [ "Q10161", "SPAC26A3.05", "Q9USZ0", "SPBC1306.02", "O43125", "SPBC119.05c", "Q10056", "SPAC1F5.09c", "Q9USR1", "SPBC577.08c", "Q01112", "SPAC110.03", "O13728", "SPAC15A10.08", "O14188", "SPAC4F8.13c", "O94466", "SPBC23G7.08c", "Q02088", "SPAC27F1.02c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10161", "SPAC26A3.05", "Q9USZ0", "SPBC1306.02", "O43125", "SPBC119.05c", "Q10056", "SPAC1F5.09c", "Q9USR1", "SPBC577.08c", "Q01112", "SPAC110.03", "O13728", "SPAC15A10.08", "O14188", "SPAC4F8.13c", "O94466", "SPBC23G7.08c", "Q02088", "SPAC27F1.02c", "species_29438", "P50527", "SPBC1604.14c" ] }, "reaction_10752666": { "compartment": "compartment_12045", "id": "reaction_10752666", "reactome": "R-SPO-6807053", "name": "SC5D desaturates LTHSOL to 7-dehydroCHOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_6807054", "species_29368" ], "products": [ "species_29366", "species_6807057", "species_29356" ], "modifiers": [ [ "species_10736341", "catalyst" ] ], "additional_components": [ "O13666", "SPBC27B12.03c", "O94457", "SPAC1687.16c" ] }, "reaction_10743177": { "compartment": "compartment_1598585", "id": "reaction_10743177", "reactome": "R-SPO-2466068", "name": "Phosphorylation of cohesin by PLK1 at chromosomal arms", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10743162" ], "products": [ "species_29370", "species_10743174" ], "modifiers": [ [ "species_10738046", "catalyst" ] ], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "O94383", "SPBC29A10.04", "P30776", "SPCC338.17c", "O94364", "SPBC428.17c", "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "Q9HFF5", "SPAC110.02", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c", "SPAC23C11.16" ] }, "reaction_10755724": { "compartment": "compartment_5460", "id": "reaction_10755724", "reactome": "R-SPO-8878815", "name": "Formation of 4Fe-4S cluster on ISCA1:ISCA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755715", "species_10755703" ], "products": [ "species_10755701", "species_10755717" ], "modifiers": [ [ "species_10755722", "catalyst" ] ], "additional_components": [ "P78859", "SPCC645.03c", "O43045", "SPBC3B9.17", "Q9HDW8", "SPAPB2B4.02", "CHEBI:33739", "SPAPB2B4.02", "CHEBI:49883", "P78859", "SPCC645.03c", "O43045", "SPBC3B9.17", "SPAC144.08" ] }, "reaction_10743108": { "compartment": "compartment_5460", "id": "reaction_10743108", "reactome": "R-SPO-2395517", "name": "NADPH transfers electrons to FDXR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_113529", "species_10743106" ], "products": [ "species_113563", "species_10743104" ], "modifiers": [], "additional_components": [ "O59710", "SPBC3B8.01c", "species_113596", "O59710", "SPBC3B8.01c", "species_31649" ] }, "reaction_10741701": { "compartment": "compartment_5460", "id": "reaction_10741701", "reactome": "R-SPO-1362416", "name": "Frataxin binds iron", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741699", "species_113531" ], "products": [ "species_10741697" ], "modifiers": [], "additional_components": [ "Q9UTC6", "SPAC227.13c", "O74831", "SPCC1183.03c", "O60068", "SPBC13G1.06c", "O74351", "SPBC21D10.11c", "Q9UTC6", "SPAC227.13c", "O74831", "SPCC1183.03c", "O60068", "SPBC13G1.06c", "O74351", "SPBC21D10.11c", "species_113531" ] }, "reaction_10754910": { "compartment": "compartment_12045", "id": "reaction_10754910", "reactome": "R-SPO-8867876", "name": "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_392417" ], "products": [ "species_1806234", "species_33625" ], "modifiers": [ [ "species_10754907", "catalyst" ] ], "additional_components": [ "O74178", "SPBC1271.12", "O94512", "SPBC646.08c", "O43021", "SPBC354.07c", "Q9UUA1", "SPCC23B6.01c" ] }, "reaction_10742025": { "compartment": "compartment_12045", "id": "reaction_10742025", "reactome": "R-SPO-1482897", "name": "PS is hydrolyzed to 2-acyl LPS by PLA2[10]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498722", "species_1524021" ], "modifiers": [ [ "species_10741988", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741912": { "compartment": "compartment_12045", "id": "reaction_10741912", "reactome": "R-SPO-1482691", "name": "2-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498722", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741897": { "compartment": "compartment_12045", "id": "reaction_10741897", "reactome": "R-SPO-1482636", "name": "1-acyl LPS is acylated to PS by LPSAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498724", "species_1500578" ], "products": [ "species_76194", "species_1500646" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741983": { "compartment": "compartment_12045", "id": "reaction_10741983", "reactome": "R-SPO-1482771", "name": "PS is hydrolyzed to 1-acyl LPS by PLA2[9]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500646", "species_29356" ], "products": [ "species_1498724", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10729620": { "compartment": "compartment_7660", "id": "reaction_10729620", "reactome": "R-SPO-69608", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10729577" ], "products": [ "species_113582", "species_10729589" ], "modifiers": [ [ "species_10729617", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC14C4.03" ] }, "reaction_10729587": { "compartment": "compartment_70101", "id": "reaction_10729587", "reactome": "R-SPO-69600", "name": "Proteolytic degradation of ubiquitinated-Cdc25A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729585" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P06652", "SPAC24H6.05", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10729608": { "compartment": "compartment_7660", "id": "reaction_10729608", "reactome": "R-SPO-69604", "name": "Phosphorylation of Cdc25A at Ser-123 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10729577" ], "products": [ "species_113582", "species_10729589" ], "modifiers": [ [ "species_10729605", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "O13945", "SPAC23H4.02", "O74536", "SPCC74.03c" ] }, "reaction_10742125": { "compartment": "compartment_70616", "id": "reaction_10742125", "reactome": "R-SPO-1483165", "name": "PA is converted to CDP-DAG by CDS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110577", "species_1524101" ], "products": [ "species_1524064", "species_159450" ], "modifiers": [ [ "species_10742122", "catalyst" ] ], "additional_components": [ "SPBC13A2.03" ] }, "reaction_10743262": { "compartment": "compartment_7660", "id": "reaction_10743262", "reactome": "R-SPO-2468040", "name": "Cohesin binds PDS5 and WAPAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743242", "species_10743244", "species_10743248" ], "products": [ "species_10743250" ], "modifiers": [], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "SPAC110.02", "SPBC428.17c", "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c" ] }, "reaction_10734651": { "compartment": "compartment_7660", "id": "reaction_10734651", "reactome": "R-SPO-156723", "name": "Regulation of KIF20A (MKL2) by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10734646" ], "products": [ "species_113582", "species_10734649" ], "modifiers": [ [ "species_10734620", "catalyst" ] ], "additional_components": [ "SPBC15D4.01c", "SPBC15D4.01c", "SPAC23C11.16" ] }, "reaction_10743288": { "compartment": "compartment_1598585", "id": "reaction_10743288", "reactome": "R-SPO-2470935", "name": "Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2537690", "species_10743250", "species_10743280" ], "products": [ "species_10743286" ], "modifiers": [], "additional_components": [ "Q92380", "SPCC4E9.01c", "O42649", "SPAC10F6.09c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c", "O94459", "SPAC1687.18c", "Q09725", "SPAC31A2.05c", "Q92380", "SPCC4E9.01c", "O94459", "SPAC1687.18c", "O42649", "SPAC10F6.09c", "Q09725", "SPAC31A2.05c", "Q9HFF5", "SPAC110.02", "O13816", "SPAC17H9.20", "P30776", "SPCC338.17c", "O94383", "SPBC29A10.04", "O94364", "SPBC428.17c" ] }, "reaction_10734623": { "compartment": "compartment_7660", "id": "reaction_10734623", "reactome": "R-SPO-156673", "name": "Regulation of KIF23 (MKLP1) by phosphorylation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10734610" ], "products": [ "species_113582", "species_10734614" ], "modifiers": [ [ "species_10734620", "catalyst" ] ], "additional_components": [ "SPBC15D4.01c", "SPBC15D4.01c", "SPAC23C11.16" ] }, "reaction_10752664": { "compartment": "compartment_5460", "id": "reaction_10752664", "reactome": "R-SPO-6806967", "name": "CARKD dehydrates S-NAD(P)HX to NADPH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807477", "species_113593" ], "products": [ "species_113548", "species_113600", "species_113581", "species_113529" ], "modifiers": [ [ "species_10752661", "catalyst" ] ], "additional_components": [ "SPCC61.03" ] }, "reaction_10752656": { "compartment": "compartment_5460", "id": "reaction_10752656", "reactome": "R-SPO-6806966", "name": "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6807473" ], "products": [ "species_6807477" ], "modifiers": [ [ "species_10752653", "catalyst" ] ], "additional_components": [ "O13725", "SPAC15A10.05c" ] }, "reaction_10753139": { "compartment": "compartment_17951", "id": "reaction_10753139", "reactome": "R-SPO-6809287", "name": "NUDT12 hydrolyses NADH to NMNH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389620", "species_141343", "species_192305" ], "products": [ "species_6809289", "species_193465" ], "modifiers": [ [ "species_10753136", "catalyst" ] ], "additional_components": [ "SPBC1778.03c" ] }, "reaction_10757787": { "compartment": "compartment_7660", "id": "reaction_10757787", "reactome": "R-SPO-9671145", "name": "DKC1 binds SHQ1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757783", "species_10734902" ], "products": [ "species_10757785" ], "modifiers": [], "additional_components": [ "SPBC8D2.13", "SPAC29A4.04c", "O43076", "SPBC8D2.13", "O14007", "SPAC29A4.04c" ] }, "reaction_10753499": { "compartment": "compartment_70101", "id": "reaction_10753499", "reactome": "R-SPO-6814119", "name": "TRiC/CCT binds unfolded G-protein beta subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738448", "species_10753491" ], "products": [ "species_10753497" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "SPBC32H8.07", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10753507": { "compartment": "compartment_70101", "id": "reaction_10753507", "reactome": "R-SPO-6814124", "name": "ATP binds G-protein beta associated TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753497" ], "products": [ "species_29370", "species_10753503" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_113592", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10738452": { "compartment": "compartment_70101", "id": "reaction_10738452", "reactome": "R-SPO-391266", "name": "Association of CCT/TriC with sphingosine kinase 1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738448", "species_10738404" ], "products": [ "species_10738450" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "SPAC4A8.07c", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "O14159", "SPAC4A8.07c", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10753505": { "compartment": "compartment_70101", "id": "reaction_10753505", "reactome": "R-SPO-6814120", "name": "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753503" ], "products": [ "species_29372", "species_10753497" ], "modifiers": [], "additional_components": [ "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_113592", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06", "P87153", "SPBC25H2.12c", "O94501", "SPBC12D12.03", "Q10282", "SPBC32H8.07", "species_29370", "Q10147", "SPAC1D4.04", "Q9UTM4", "SPAC1420.02c", "O94515", "SPBC646.11", "P78921", "SPBC337.05c", "O74341", "SPBC1A4.08c", "P50999", "SPBC106.06" ] }, "reaction_10752940": { "compartment": "compartment_6791047", "id": "reaction_10752940", "reactome": "R-SPO-6807877", "name": "ARFGAPs stimulate ARF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752857" ], "products": [ "species_10752937", "species_10752792", "species_10746137", "species_10752725" ], "modifiers": [ [ "species_10752857", "catalyst" ] ], "additional_components": [ "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "O13728", "SPAC15A10.08", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O60073", "SPBC13G1.11", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "O13932", "SPAC23C4.13", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "Q09857", "SPAC29E6.03c", "O13946", "SPAC23H4.03c", "O13728", "SPAC15A10.08", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "O42937", "SPBC16C6.13c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "O60073", "SPBC13G1.11", "Q9P7I9", "SPCC24B10.17", "O13932", "SPAC23C4.13", "P11620", "SPBC1703.10", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "Q09857", "SPAC29E6.03c", "SPAC22E12.17c", "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "O13728", "SPAC15A10.08", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O60073", "SPBC13G1.11", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "O13932", "SPAC23C4.13", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "Q09857", "SPAC29E6.03c" ] }, "reaction_10753303": { "compartment": "compartment_12045", "id": "reaction_10753303", "reactome": "R-SPO-6811425", "name": "NSF and SNAPs bind cis-SNARE at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753301", "species_10739129", "species_10749814" ], "products": [ "species_10753292" ], "modifiers": [], "additional_components": [ "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "O13785", "SPAC17G6.07c", "O42852", "SPAC23A1.15c", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "Q9P4X4", "SPAC959.02", "O13785", "SPAC17G6.07c", "Q9P7Q4", "SPAC1834.11c", "O42852", "SPAC23A1.15c" ] }, "reaction_10749851": { "compartment": "compartment_6791047", "id": "reaction_10749851", "reactome": "R-SPO-5694423", "name": "NSF and SNAPs bind cis-SNARE complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10749847", "species_10749814" ], "products": [ "species_10749849" ], "modifiers": [], "additional_components": [ "SPAC959.02", "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P7Q4", "SPAC1834.11c", "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10754292": { "compartment": "compartment_17938", "id": "reaction_10754292", "reactome": "R-SPO-8854255", "name": "TBC1D2A accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754282", "species_29356" ], "products": [ "species_29372", "species_10754284" ], "modifiers": [ [ "species_10754282", "catalyst" ], [ "species_10754290", "catalyst" ] ], "additional_components": [ "O94655", "SPBC405.04c", "CHEBI:15996", "species_29420", "O94655", "SPBC405.04c", "O94655", "SPBC405.04c", "CHEBI:15996", "SPAC4G8.04" ] }, "reaction_10740660": { "compartment": "compartment_70101", "id": "reaction_10740660", "reactome": "R-SPO-917700", "name": "MVB Vesicle Formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740430", "species_10740658" ], "products": [ "species_10740526", "species_10740656" ], "modifiers": [], "additional_components": [ "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "P0CH07", "SPAC1805.12c", "O74967", "SPBC4B4.06", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O43038", "SPBC3B9.09", "species_179838", "O94663", "SPBC651.05c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "P0C8R3", "SPAC589.10c", "O14296", "SPAC9E9.14", "species_179838", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "P0CH06", "SPAC11G7.04", "O74967", "SPBC4B4.06", "O43038", "SPBC3B9.09", "O94663", "SPBC651.05c" ] }, "reaction_10753584": { "compartment": "compartment_6791047", "id": "reaction_10753584", "reactome": "R-SPO-6814833", "name": "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753579" ], "products": [ "species_10749719", "species_10753577" ], "modifiers": [ [ "species_10753579", "catalyst" ] ], "additional_components": [ "P11620", "SPBC1703.10", "species_29438", "O94661", "SPBC651.03c", "species_29420", "P11620", "SPBC1703.10", "SPBC651.03c", "P11620", "SPBC1703.10", "species_29438", "O94661", "SPBC651.03c" ] }, "reaction_10754588": { "compartment": "compartment_876", "id": "reaction_10754588", "reactome": "R-SPO-8862280", "name": "FCHo proteins bind nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754497", "species_10754509", "species_10754481", "species_10754426", "species_10754471", "species_10754491" ], "products": [ "species_10754511" ], "modifiers": [], "additional_components": [ "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "species_179856", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "Q9USZ7", "SPBC11G11.02c", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "O94685", "SPBC83.01", "Q9USZ7", "SPBC11G11.02c", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "O94685", "SPBC83.01", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "Q9USZ7", "SPBC11G11.02c", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "O94685", "SPBC83.01", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q9Y7L6", "SPBC685.04c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_179856", "O94685", "SPBC83.01" ] }, "reaction_10755426": { "compartment": "compartment_876", "id": "reaction_10755426", "reactome": "R-SPO-8871196", "name": "Initial binding of AP-2 and clathrin to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754388", "species_10738801", "species_179856" ], "products": [ "species_10754497" ], "modifiers": [], "additional_components": [ "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "species_179856" ] }, "reaction_10753408": { "compartment": "compartment_263163", "id": "reaction_10753408", "reactome": "R-SPO-6811428", "name": "RIC1:RGP1 recruits RAB6:GDP to the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753400", "species_10753388" ], "products": [ "species_10753406" ], "modifiers": [], "additional_components": [ "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "species_29420", "P17608", "SPAC4C5.02c", "species_29420", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c" ] }, "reaction_10753602": { "compartment": "compartment_263163", "id": "reaction_10753602", "reactome": "R-SPO-8847534", "name": "RAB43 hydrolyses GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753595" ], "products": [ "species_10753599" ], "modifiers": [ [ "species_10753595", "catalyst" ] ], "additional_components": [ "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "species_29438", "species_29420", "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "species_29438" ] }, "reaction_10755664": { "compartment": "compartment_13946", "id": "reaction_10755664", "reactome": "R-SPO-8877475", "name": "TRAPPC complexes exchange GTP for GDP on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755636" ], "products": [ "species_10755437", "species_10755646", "species_29420" ], "modifiers": [ [ "species_10755661", "catalyst" ] ], "additional_components": [ "species_29420", "P11620", "SPBC1703.10", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P11620", "SPBC1703.10", "species_29438", "O74748", "SPBC1734.07c", "O14251", "SPAC6G10.05c", "Q9UT70", "SPAC3G9.16c", "Q9USZ5", "SPBC11G11.04", "Q9P6P5", "SPAC644.18c", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O13732", "SPAC15A10.12c", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12" ] }, "reaction_10753415": { "compartment": "compartment_263163", "id": "reaction_10753415", "reactome": "R-SPO-6811429", "name": "RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10753406" ], "products": [ "species_29420", "species_10753412" ], "modifiers": [ [ "species_10753406", "catalyst" ] ], "additional_components": [ "species_29420", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c", "species_29438", "species_29420", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c", "P17608", "SPAC4C5.02c" ] }, "reaction_10755452": { "compartment": "compartment_216813", "id": "reaction_10755452", "reactome": "R-SPO-8875318", "name": "RAB3 GEFs exchange GTP for GDP on RAB3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755439" ], "products": [ "species_10755437", "species_10755447", "species_29420" ], "modifiers": [ [ "species_10755449", "catalyst" ] ], "additional_components": [ "species_29420", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17609", "SPAC9E9.07c", "species_29438", "O13876", "SPAC1B3.11c", "SPAC23C4.10" ] }, "reaction_10755040": { "compartment": "compartment_876", "id": "reaction_10755040", "reactome": "R-SPO-8868651", "name": "Endophilins recruit synaptojanins to the clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755020", "species_10742387" ], "products": [ "species_10755033" ], "modifiers": [], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856", "SPBC2G2.02", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10753710": { "compartment": "compartment_20699", "id": "reaction_10753710", "reactome": "R-SPO-8847883", "name": "CYTH proteins stimulate ARF1 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753701" ], "products": [ "species_10753707" ], "modifiers": [ [ "species_10753701", "catalyst" ] ], "additional_components": [ "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753246": { "compartment": "compartment_20699", "id": "reaction_10753246", "reactome": "R-SPO-6811414", "name": "GBF1 stimulates nucleotide exchange on ARF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10753235" ], "products": [ "species_10753239", "species_29420" ], "modifiers": [ [ "species_10753235", "catalyst" ] ], "additional_components": [ "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10754846": { "compartment": "compartment_876", "id": "reaction_10754846", "reactome": "R-SPO-8867613", "name": "PICALM binds R-SNAREs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738025", "species_10754842" ], "products": [ "species_10754844" ], "modifiers": [], "additional_components": [ "SPAC6G9.11", "O60167", "SPBC19F8.03c", "Q92356", "SPAC6G9.11", "O60167", "SPBC19F8.03c" ] }, "reaction_10753617": { "compartment": "compartment_20699", "id": "reaction_10753617", "reactome": "R-SPO-8847638", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753612" ], "products": [ "species_29370", "species_10753102", "species_10739129", "species_10753091", "species_10749814", "species_10753100", "species_10753002" ], "modifiers": [ [ "species_10753612", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "SPBC8D2.14c", "SPAC959.02", "SPAC4G8.10", "Q9P7Q4", "SPAC1834.11c", "Q09730", "SPAC31A2.13c", "O13932", "SPAC23C4.13", "SPBC13G1.11", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10737431": { "compartment": "compartment_70101", "id": "reaction_10737431", "reactome": "R-SPO-203977", "name": "SAR1 Activation And Membrane Binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10737423" ], "products": [ "species_10737349", "species_29420" ], "modifiers": [ [ "species_10737428", "catalyst" ] ], "additional_components": [ "species_29420", "Q01475", "SPBC31F10.06c", "Q01475", "SPBC31F10.06c", "species_29438", "SPBC3H7.01" ] }, "reaction_10749854": { "compartment": "compartment_6791047", "id": "reaction_10749854", "reactome": "R-SPO-5694425", "name": "NSF ATPase activity dissociates cis-SNARE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10749849" ], "products": [ "species_10749821", "species_10749837", "species_10739129", "species_10749828", "species_10749814", "species_10749845", "species_29372", "species_10749823" ], "modifiers": [ [ "species_10749849", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "SPAC23C4.13", "O13644", "SPBC8D2.14c", "O94651", "SPBC31E1.04", "SPAC959.02", "SPCC74.01", "Q9P7Q4", "SPAC1834.11c", "O60073", "SPBC13G1.11", "Q9Y7L0", "SPBC2A9.08c", "SPAP14E8.03", "O13644", "SPBC8D2.14c", "O74534", "SPCC74.01", "O60073", "SPBC13G1.11", "O94651", "SPBC31E1.04", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O13932", "SPAC23C4.13", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10753581": { "compartment": "compartment_6791047", "id": "reaction_10753581", "reactome": "R-SPO-6814831", "name": "TBC1D20 binds RAB1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753577", "species_10749883" ], "products": [ "species_10753579" ], "modifiers": [], "additional_components": [ "SPBC651.03c", "P11620", "SPBC1703.10", "species_29438", "P11620", "SPBC1703.10", "species_29438", "O94661", "SPBC651.03c" ] }, "reaction_10754326": { "compartment": "compartment_17938", "id": "reaction_10754326", "reactome": "R-SPO-8854329", "name": "TBC1D15 accelerates GTP hydrolysis by RAB7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10754316" ], "products": [ "species_10754318", "species_29372" ], "modifiers": [ [ "species_10754316", "catalyst" ], [ "species_10754324", "catalyst" ] ], "additional_components": [ "O94655", "SPBC405.04c", "Q9HDY0", "SPAPB1A10.10c", "CHEBI:15996", "O94655", "SPBC405.04c", "Q9HDY0", "SPAPB1A10.10c", "species_111349", "O94655", "SPBC405.04c", "Q9HDY0", "SPAPB1A10.10c", "CHEBI:15996", "SPAC630.05" ] }, "reaction_10753567": { "compartment": "compartment_263163", "id": "reaction_10753567", "reactome": "R-SPO-6814684", "name": "cis-SNARE binds SNAPs and NSF hexamer at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10753563", "species_10749814" ], "products": [ "species_10753565" ], "modifiers": [], "additional_components": [ "SPAC959.02", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q9P6P1", "SPAC823.05c", "Q9P7Q4", "SPAC1834.11c", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c" ] }, "reaction_10752744": { "compartment": "compartment_6791047", "id": "reaction_10752744", "reactome": "R-SPO-6807868", "name": "GBF1 stimulates ARF nucleotide exchange", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10752737" ], "products": [ "species_29370", "species_10752741" ], "modifiers": [ [ "species_10752737", "catalyst" ] ], "additional_components": [ "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10754916": { "compartment": "compartment_876", "id": "reaction_10754916", "reactome": "R-SPO-8868072", "name": "Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_202247" ], "modifiers": [ [ "species_10754884", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9USP6", "SPBC9B6.08", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10757826": { "compartment": "compartment_70101", "id": "reaction_10757826", "reactome": "R-SPO-9681616", "name": "AP2 binds chlorpromazine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754388", "species_9648300" ], "products": [ "species_10754724" ], "modifiers": [], "additional_components": [ "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_9648300", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10754525": { "compartment": "compartment_876", "id": "reaction_10754525", "reactome": "R-SPO-8856813", "name": "AAK1 phosphorylates AP-2 mu subunit at T156", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10754515" ], "products": [ "species_29370", "species_10754522" ], "modifiers": [ [ "species_10754515", "catalyst" ] ], "additional_components": [ "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_179856", "O94685", "SPBC83.01", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O94685", "SPBC83.01", "species_179856", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_179856", "O94685", "SPBC83.01", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02" ] }, "reaction_10755038": { "compartment": "compartment_876", "id": "reaction_10755038", "reactome": "R-SPO-8868648", "name": "SYNJ hydrolyze PI(4,5)P2 to PI(4)P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755033", "species_29356" ], "products": [ "species_29372", "species_10755035" ], "modifiers": [ [ "species_10755033", "catalyst" ] ], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "species_1806234", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "species_29438", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10749891": { "compartment": "compartment_6791047", "id": "reaction_10749891", "reactome": "R-SPO-5694441", "name": "CSNK1D phosphorylates SEC23", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10749871" ], "products": [ "species_29370", "species_10749807", "species_10737297", "species_10749877", "species_10749883", "species_10749768", "species_10749875" ], "modifiers": [ [ "species_10749888", "catalyst" ] ], "additional_components": [ "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q10149", "SPAC1D4.02c", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15", "Q09857", "SPAC29E6.03c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13637", "SPBC8D2.20c", "O94319", "SPBC215.15", "P87109", "SPAC20G8.02", "O13644", "SPBC8D2.14c", "O60073", "SPBC13G1.11", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q10149", "SPAC1D4.02c", "Q9Y7L0", "SPBC2A9.08c", "Q9USS7", "SPBC4.03c", "Q09857", "SPAC29E6.03c", "P11620", "SPBC1703.10", "species_29438", "O14251", "SPAC6G10.05c", "Q9UT70", "SPAC3G9.16c", "Q9USZ5", "SPBC11G11.04", "Q9P6P5", "SPAC644.18c", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O13732", "SPAC15A10.12c", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "SPCC31H12.07", "SPBC3H7.15" ] }, "reaction_10737888": { "compartment": "compartment_70101", "id": "reaction_10737888", "reactome": "R-SPO-350769", "name": "trans-Golgi Network Coat Activation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10737859" ], "products": [ "species_10737863", "species_29420" ], "modifiers": [ [ "species_10737885", "catalyst" ] ], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "P36579", "SPBC4F6.18c", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753554": { "compartment": "compartment_263163", "id": "reaction_10753554", "reactome": "R-SPO-6814676", "name": "SNAPs and NSF hexamer bind cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10753550", "species_10749814" ], "products": [ "species_10753552" ], "modifiers": [], "additional_components": [ "SPAC959.02", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P6P1", "SPAC823.05c", "Q9P7Q4", "SPAC1834.11c", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c" ] }, "reaction_10753606": { "compartment": "compartment_263163", "id": "reaction_10753606", "reactome": "R-SPO-8847537", "name": "RAB43:GTP binds USP8NL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753593", "species_10753604" ], "products": [ "species_10753595" ], "modifiers": [], "additional_components": [ "P11620", "SPBC1703.10", "species_29438", "SPAC26F1.09", "Q10496", "SPAC26F1.09", "P11620", "SPBC1703.10", "species_29438" ] }, "reaction_10755079": { "compartment": "compartment_24339", "id": "reaction_10755079", "reactome": "R-SPO-8868658", "name": "HSPA8-mediated ATP hydrolysis promotes vesicle uncoating", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755070", "species_29356" ], "products": [ "species_10755072", "species_10755076", "species_29372" ], "modifiers": [ [ "species_10755070", "catalyst" ] ], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q10265", "SPAC13G7.02c", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "species_29370", "Q10265", "SPAC13G7.02c", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q10265", "SPAC13G7.02c", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10749918": { "compartment": "compartment_70101", "id": "reaction_10749918", "reactome": "R-SPO-5694527", "name": "Loss of SAR1B GTPase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737373" ], "products": [ "species_10737439", "species_29372", "species_10737371", "species_10737423" ], "modifiers": [ [ "species_10737373", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9USS7", "SPBC4.03c", "species_29420", "Q01475", "SPBC31F10.06c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438" ] }, "reaction_10753635": { "compartment": "compartment_20699", "id": "reaction_10753635", "reactome": "R-SPO-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742399", "species_10753631" ], "products": [ "species_10753633" ], "modifiers": [], "additional_components": [ "P36579", "SPBC4F6.18c", "CHEBI:15996", "O42903", "SPBC119.12", "O60109", "SPBC14F5.13c", "O42903", "SPBC119.12", "P36579", "SPBC4F6.18c", "O60109", "SPBC14F5.13c", "CHEBI:15996" ] }, "reaction_10752733": { "compartment": "compartment_6791047", "id": "reaction_10752733", "reactome": "R-SPO-6807864", "name": "RAB1:GTP recruits GBF1 to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752729", "species_10749883", "species_10752725" ], "products": [ "species_10752731" ], "modifiers": [], "additional_components": [ "Q09857", "SPAC29E6.03c", "P11620", "SPBC1703.10", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753120": { "compartment": "compartment_20699", "id": "reaction_10753120", "reactome": "R-SPO-6809014", "name": "cis-Golgi cis-SNARE binds NSF and SNAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10749814", "species_10753116" ], "products": [ "species_10753118" ], "modifiers": [], "additional_components": [ "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10753237": { "compartment": "compartment_20699", "id": "reaction_10753237", "reactome": "R-SPO-6811411", "name": "GBF1 recruits ARF:GDP to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746137", "species_10753233" ], "products": [ "species_10753235" ], "modifiers": [], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10753123": { "compartment": "compartment_20699", "id": "reaction_10753123", "reactome": "R-SPO-6809015", "name": "NSF ATPase activity dissociates cis-SNARE at cis-Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753118", "species_113592" ], "products": [ "species_10753102", "species_10753106", "species_10753091", "species_29372", "species_10753100", "species_10753074", "species_10753002" ], "modifiers": [ [ "species_10753118", "catalyst" ] ], "additional_components": [ "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "SPBC8D2.14c", "SPAP14E8.03", "SPAC4G8.10", "Q09730", "SPAC31A2.13c", "O13932", "SPAC23C4.13", "SPAC23C4.13", "SPBC13G1.11", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "Q9P7G5", "SPAP14E8.03", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10753260": { "compartment": "compartment_20699", "id": "reaction_10753260", "reactome": "R-SPO-6811417", "name": "ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752792", "species_10753256", "species_10753241", "species_10753250", "species_10753070" ], "products": [ "species_10753258" ], "modifiers": [], "additional_components": [ "SPAC22E12.17c", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P36579", "SPBC4F6.18c", "P87140", "SPAC57A7.10c", "P11620", "SPBC1703.10", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "SPBC2A9.08c", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06" ] }, "reaction_10737445": { "compartment": "compartment_12045", "id": "reaction_10737445", "reactome": "R-SPO-204008", "name": "SEC31:SEC13 and v-SNARE recruitment", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737297", "species_10737379", "species_10737310" ], "products": [ "species_10737381" ], "modifiers": [], "additional_components": [ "O13637", "SPBC8D2.20c", "O94319", "SPBC215.15", "P87109", "SPAC20G8.02", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "O14029", "SPAC29B12.07", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O60073", "SPBC13G1.11", "Q9Y7L0", "SPBC2A9.08c", "O13637", "SPBC8D2.20c", "O14029", "SPAC29B12.07", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "P87109", "SPAC20G8.02", "O13644", "SPBC8D2.14c", "O60073", "SPBC13G1.11", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "O94319", "SPBC215.15" ] }, "reaction_10754333": { "compartment": "compartment_5683628", "id": "reaction_10754333", "reactome": "R-SPO-8854588", "name": "TBC1D25 (OATL1) binds ATG8 homologues", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747277", "species_10754329" ], "products": [ "species_10754331" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "SPAC630.05", "O94272", "SPBP8B7.24c", "Q9UUH7", "SPAC630.05" ] }, "reaction_10754886": { "compartment": "compartment_876", "id": "reaction_10754886", "reactome": "R-SPO-8867756", "name": "CLASP proteins and cargo are recruited to the nascent clathrin-coated pit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754878", "species_10754522" ], "products": [ "species_10754880" ], "modifiers": [], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9P7V2", "SPAC30.04c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q09718", "SPAC31A2.09c", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q9Y7L6", "SPBC685.04c", "Q09697", "SPAC13A11.01c", "Q9HGL2", "SPBC800.10c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "O94685", "SPBC83.01", "species_179856", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "O43059", "SPBC4C3.06", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q10172", "SPAC25G10.09c", "Q9USS2", "SPBC557.04", "Q9USP6", "SPBC9B6.08", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10755085": { "compartment": "compartment_24339", "id": "reaction_10755085", "reactome": "R-SPO-8868659", "name": "Clathrin recruits auxilins to the clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755081", "species_10739268" ], "products": [ "species_10755083" ], "modifiers": [], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "SPAC17A5.12", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10749791": { "compartment": "compartment_12045", "id": "reaction_10749791", "reactome": "R-SPO-5694413", "name": "SEC4C,D bind GOSR2 and STX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737367", "species_10737361", "species_10737369" ], "products": [ "species_10737371" ], "modifiers": [], "additional_components": [ "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "Q9P7G5", "SPAP14E8.03", "SPCC31H12.07", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9USS7", "SPBC4.03c" ] }, "reaction_10754599": { "compartment": "compartment_70101", "id": "reaction_10754599", "reactome": "R-SPO-8863727", "name": "STON2 is neddylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754595", "species_10749451" ], "products": [ "species_10754591" ], "modifiers": [], "additional_components": [ "SPAC31A2.09c", "SPBC12D12.08c", "SPAC31A2.09c" ] }, "reaction_10753248": { "compartment": "compartment_20699", "id": "reaction_10753248", "reactome": "R-SPO-6811415", "name": "RAB:GTP recruits GBF1 to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753032", "species_10752725" ], "products": [ "species_10753233" ], "modifiers": [], "additional_components": [ "P11620", "SPBC1703.10", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10738021": { "compartment": "compartment_70101", "id": "reaction_10738021", "reactome": "R-SPO-376364", "name": "Vamp8 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738012", "species_10738014", "species_10738010" ], "products": [ "species_10738012", "species_10738016", "species_10738010" ], "modifiers": [ [ "species_10738018", "catalyst" ] ], "additional_components": [ "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "Q92356", "SPAC6G9.11", "O74786", "SPBC26H8.02c", "Q9USH7", "SPCC825.03c" ] }, "reaction_10753384": { "compartment": "compartment_12045", "id": "reaction_10753384", "reactome": "R-SPO-6811427", "name": "COPI vesicle uncoating at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753382" ], "products": [ "species_10753301", "species_10749719", "species_10753380", "species_10752783", "species_10753346" ], "modifiers": [], "additional_components": [ "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "O42852", "SPAC23A1.15c", "O42937", "SPBC16C6.13c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "P11620", "SPBC1703.10", "Q9C0W8", "SPBC691.02c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O13785", "SPAC17G6.07c", "O74559", "SPCC970.06", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "O13785", "SPAC17G6.07c", "O42852", "SPAC23A1.15c", "species_29420", "P11620", "SPBC1703.10", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "O42937", "SPBC16C6.13c", "Q9P7I9", "SPCC24B10.17", "O13946", "SPAC23H4.03c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c" ] }, "reaction_10755090": { "compartment": "compartment_876", "id": "reaction_10755090", "reactome": "R-SPO-8868661", "name": "Dynamin-mediated GTP hydrolysis promotes vesicle scission", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10755035" ], "products": [ "species_10755081", "species_29372" ], "modifiers": [ [ "species_10755035", "catalyst" ] ], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "species_1806234", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "species_29438", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "species_1806234", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "species_29438", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10753713": { "compartment": "compartment_20699", "id": "reaction_10753713", "reactome": "R-SPO-8848484", "name": "PLA2s hydrolyze phospholipids at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429785", "species_29356" ], "products": [ "species_6814303", "species_8848483" ], "modifiers": [ [ "species_10739104", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10740639": { "compartment": "compartment_74700", "id": "reaction_10740639", "reactome": "R-SPO-917693", "name": "ESCRT Disassembly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740526", "species_113592" ], "products": [ "species_10740409", "species_29370", "species_10740404", "species_10740428", "species_10740414", "species_10740423", "species_29372", "species_10740620" ], "modifiers": [ [ "species_10740636", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "P0C8R3", "SPAC589.10c", "O14296", "SPAC9E9.14", "species_179838", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "P0CH06", "SPAC11G7.04", "SPAC9E9.14", "SPAC4F8.01", "SPCC162.06c", "SPAC1142.07c", "SPBC215.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "species_179838", "P0CH06", "SPAC11G7.04", "O74422", "SPCC162.06c", "Q09803", "SPAC2G11.06", "O13703", "SPAC13F5.04c" ] }, "reaction_10753614": { "compartment": "compartment_20699", "id": "reaction_10753614", "reactome": "R-SPO-8847637", "name": "NSF and SNAPs bind the cis-SNARE at the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739129", "species_10749814", "species_10753610" ], "products": [ "species_10753612" ], "modifiers": [], "additional_components": [ "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "O13644", "SPBC8D2.14c", "Q09730", "SPAC31A2.13c", "O60073", "SPBC13G1.11", "O13932", "SPAC23C4.13", "Q09835", "SPAC4G8.10", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c" ] }, "reaction_10749856": { "compartment": "compartment_13959", "id": "reaction_10749856", "reactome": "R-SPO-5694439", "name": "COPII coat binds TRAPPCII and RAB1:GDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749719", "species_10749768", "species_10737419" ], "products": [ "species_10749770" ], "modifiers": [], "additional_components": [ "species_29420", "P11620", "SPBC1703.10", "O14251", "SPAC6G10.05c", "Q9UT70", "SPAC3G9.16c", "Q9USZ5", "SPBC11G11.04", "Q9P6P5", "SPAC644.18c", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O13732", "SPAC15A10.12c", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "O60073", "SPBC13G1.11", "O13637", "SPBC8D2.20c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9Y7L0", "SPBC2A9.08c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O94319", "SPBC215.15", "P87109", "SPAC20G8.02", "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "species_29420", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "Q09784", "SPAC13G6.05c", "P11620", "SPBC1703.10", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15" ] }, "reaction_10753557": { "compartment": "compartment_263163", "id": "reaction_10753557", "reactome": "R-SPO-6814678", "name": "ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753552", "species_113592" ], "products": [ "species_10753539", "species_29370", "species_10739129", "species_10753544", "species_10753548", "species_10753546", "species_10749814" ], "modifiers": [ [ "species_10753552", "catalyst" ] ], "additional_components": [ "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c", "SPBC36B7.07", "SPAC959.02", "SPAC823.05c", "SPAC6G9.11", "SPBC3B9.10", "Q9P7Q4", "SPAC1834.11c", "P78768", "SPBC3B9.10", "Q9HGN3", "SPBC36B7.07", "Q92356", "SPAC6G9.11", "Q9P4X4", "SPAC959.02", "Q9P7Q4", "SPAC1834.11c", "Q9P6P1", "SPAC823.05c" ] }, "reaction_10753703": { "compartment": "compartment_20699", "id": "reaction_10753703", "reactome": "R-SPO-8847880", "name": "CYTH proteins bind ARF1:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742399", "species_10753667" ], "products": [ "species_10753701" ], "modifiers": [], "additional_components": [ "P36579", "SPBC4F6.18c", "CHEBI:15996", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "CHEBI:15996", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10749795": { "compartment": "compartment_12045", "id": "reaction_10749795", "reactome": "R-SPO-5694415", "name": "SEC24A,B:SEC23A bind SEC22B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737433", "species_10737302", "species_10737369" ], "products": [ "species_10749793" ], "modifiers": [], "additional_components": [ "SPAC22F8.08", "SPBC2A9.08c", "SPCC31H12.07", "O74873", "SPCC31H12.07", "Q9Y7L0", "SPBC2A9.08c", "Q9UUI5", "SPAC22F8.08" ] }, "reaction_10752739": { "compartment": "compartment_6791047", "id": "reaction_10752739", "reactome": "R-SPO-6807866", "name": "GBF1 recruits ARF:GDP to the ERGIC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746137", "species_10752731" ], "products": [ "species_10752737" ], "modifiers": [], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "species_29420", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10754348": { "compartment": "compartment_262783", "id": "reaction_10754348", "reactome": "R-SPO-8854759", "name": "TBC1D14 binds RAB11 and ULK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754344", "species_10754335", "species_10754339" ], "products": [ "species_10754346" ], "modifiers": [], "additional_components": [ "SPAC23D3.03c", "SPAC18G6.03", "SPCC63.08c", "P17610", "SPAC18G6.03", "Q9Y7T4", "SPCC63.08c", "Q09844", "SPAC23D3.03c" ] }, "reaction_10749777": { "compartment": "compartment_13959", "id": "reaction_10749777", "reactome": "R-SPO-5694409", "name": "Nucleotide exchange on RAB1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10749770" ], "products": [ "species_10749774", "species_29420" ], "modifiers": [ [ "species_10749770", "catalyst" ] ], "additional_components": [ "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "species_29420", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "Q09784", "SPAC13G6.05c", "P11620", "SPBC1703.10", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15", "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q09784", "SPAC13G6.05c", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15", "Q9UT70", "SPAC3G9.16c", "O13637", "SPBC8D2.20c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13732", "SPAC15A10.12c", "P87109", "SPAC20G8.02", "O74501", "SPCC285.14", "O43041", "SPBC3B9.12", "O13644", "SPBC8D2.14c", "species_29420", "O14251", "SPAC6G10.05c", "O60073", "SPBC13G1.11", "Q9USZ5", "SPBC11G11.04", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9P6P5", "SPAC644.18c", "Q9Y7L0", "SPBC2A9.08c", "Q09784", "SPAC13G6.05c", "P11620", "SPBC1703.10", "Q9P7N9", "SPBC1718.05", "O94319", "SPBC215.15" ] }, "reaction_10754306": { "compartment": "compartment_262783", "id": "reaction_10754306", "reactome": "R-SPO-8854293", "name": "TBC1D10A (EPI64) binds ARF6:GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754295", "species_10754302" ], "products": [ "species_10754304" ], "modifiers": [], "additional_components": [ "SPBC1778.09", "Q9Y7Z2", "SPBC1539.08", "species_29438", "Q9Y7J5", "SPBC1778.09", "Q9Y7Z2", "SPBC1539.08", "species_29438" ] }, "reaction_10755558": { "compartment": "compartment_263163", "id": "reaction_10755558", "reactome": "R-SPO-8876193", "name": "RIC1-RGP1 exchanges GTP for GDP on RAB6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755545" ], "products": [ "species_10755437", "species_10755549", "species_29420" ], "modifiers": [ [ "species_10755555", "catalyst" ] ], "additional_components": [ "species_29420", "P17608", "SPAC4C5.02c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17608", "SPAC4C5.02c", "species_29438", "O60183", "SPBC23E6.08", "O42656", "SPAC1851.04c" ] }, "reaction_10745653": { "compartment": "compartment_263163", "id": "reaction_10745653", "reactome": "R-SPO-5333658", "name": "CLAT:AP1:CLVS bind PI(3,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745649", "species_5334668" ], "products": [ "species_10745651" ], "modifiers": [], "additional_components": [ "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "Q9UU81", "SPCP1E11.06", "Q9HFE5", "SPBP16F5.07", "O43079", "SPBC947.02", "Q9P7N2", "SPAP27G11.06c", "Q9USP6", "SPBC9B6.08", "Q10161", "SPAC26A3.05", "species_6809774", "Q9UU81", "SPCP1E11.06", "Q9HFE5", "SPBP16F5.07", "O43079", "SPBC947.02", "Q9P7N2", "SPAP27G11.06c" ] }, "reaction_10753295": { "compartment": "compartment_12045", "id": "reaction_10753295", "reactome": "R-SPO-6811422", "name": "NSF ATPase activity dissociates cis-SNARE at the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753292" ], "products": [ "species_10753288", "species_10753278", "species_10739129", "species_10753283", "species_10737302", "species_10749814", "species_29372" ], "modifiers": [ [ "species_10753292", "catalyst" ] ], "additional_components": [ "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "Q9P4X4", "SPAC959.02", "O13785", "SPAC17G6.07c", "Q9P7Q4", "SPAC1834.11c", "O42852", "SPAC23A1.15c", "SPAC17G6.07c", "SPAC23A1.15c", "SPAC959.02", "SPCC895.04c", "SPBC2A9.08c", "Q9P7Q4", "SPAC1834.11c", "Q9Y7L0", "SPBC2A9.08c", "O94531", "SPCC895.04c", "Q9P4X4", "SPAC959.02", "O13785", "SPAC17G6.07c", "Q9P7Q4", "SPAC1834.11c", "O42852", "SPAC23A1.15c" ] }, "reaction_10755022": { "compartment": "compartment_876", "id": "reaction_10755022", "reactome": "R-SPO-8868236", "name": "BAR domain proteins recruit dynamin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755018", "species_10755016" ], "products": [ "species_10755020" ], "modifiers": [], "additional_components": [ "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "species_29438", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q9P6L5", "SPAC688.11", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O60054", "SPBC56F2.03", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_29438", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_179856" ] }, "reaction_10738030": { "compartment": "compartment_876", "id": "reaction_10738030", "reactome": "R-SPO-376369", "name": "Vamp2 associated secretory vesicle to plasma membrane transport", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738012", "species_10738023", "species_10738010" ], "products": [ "species_10738012", "species_10738025", "species_10738010" ], "modifiers": [ [ "species_10738027", "catalyst" ] ], "additional_components": [ "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "SPCC825.03c", "SPAC6G9.11", "SPBC26H8.02c", "Q92356", "SPAC6G9.11", "O74786", "SPBC26H8.02c", "Q9USH7", "SPCC825.03c" ] }, "reaction_10754913": { "compartment": "compartment_876", "id": "reaction_10754913", "reactome": "R-SPO-8868066", "name": "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_392417" ], "products": [ "species_29370", "species_179856" ], "modifiers": [ [ "species_10742317", "catalyst" ] ], "additional_components": [ "SPAC19G12.14" ] }, "reaction_10753273": { "compartment": "compartment_20699", "id": "reaction_10753273", "reactome": "R-SPO-6811418", "name": "ARFGAPs stimulate ARF GTPase activity at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753258" ], "products": [ "species_10752792", "species_10746137", "species_10752725", "species_10753270" ], "modifiers": [ [ "species_10753258", "catalyst" ] ], "additional_components": [ "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "SPAC22E12.17c", "species_29420", "P36579", "SPBC4F6.18c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "O42937", "SPBC16C6.13c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06", "O13690", "SPBC211.03c", "O13946", "SPAC23H4.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "Q9P7I9", "SPCC24B10.17", "P36579", "SPBC4F6.18c", "Q9Y7L0", "SPBC2A9.08c", "P11620", "SPBC1703.10", "Q10367", "SPAC22E12.17c", "O13770", "SPAC17A5.08", "O14324", "SPBC16E9.09c", "O94270", "SPBP8B7.22", "O74559", "SPCC970.06" ] }, "reaction_10755570": { "compartment": "compartment_70101", "id": "reaction_10755570", "reactome": "R-SPO-8876446", "name": "p-ULK1 phosphorylates DENND3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755563", "species_113592" ], "products": [ "species_29370", "species_10755567" ], "modifiers": [ [ "species_10746793", "catalyst" ] ], "additional_components": [ "SPCC297.05", "SPCC297.05", "SPCC63.08c" ] }, "reaction_10753243": { "compartment": "compartment_20699", "id": "reaction_10753243", "reactome": "R-SPO-6811412", "name": "Active ARF recruits coatomer to the Golgi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752783", "species_10753239" ], "products": [ "species_10753241" ], "modifiers": [], "additional_components": [ "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "O42937", "SPBC16C6.13c", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P36579", "SPBC4F6.18c", "P87140", "SPAC57A7.10c", "P11620", "SPBC1703.10", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10755087": { "compartment": "compartment_24339", "id": "reaction_10755087", "reactome": "R-SPO-8868660", "name": "Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755083", "species_10755046" ], "products": [ "species_10755070" ], "modifiers": [], "additional_components": [ "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01", "species_113592", "Q10265", "SPAC13G7.02c", "P78774", "SPBC14C8.06", "O43125", "SPBC119.05c", "Q10316", "SPAC17G8.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "Q92356", "SPAC6G9.11", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "O60054", "SPBC56F2.03", "Q9HGL2", "SPBC800.10c", "P32390", "SPAC630.03", "P10989", "SPBC32H8.12c", "Q9C0W7", "SPBC691.03c", "species_29420", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "species_1806234", "Q09748", "SPBC12C2.08", "Q9P6L5", "SPAC688.11", "Q10265", "SPAC13G7.02c", "Q9URZ5", "SPAC767.01c", "Q9P7E8", "SPAPJ760.02c", "Q9Y7J4", "SPBC1778.08c", "Q9UU85", "SPCP1E11.02", "O43066", "SPBC6B1.02", "Q9UUJ1", "SPAC11H11.06", "O13773", "SPAC17A5.12", "O43059", "SPBC4C3.06", "O14241", "SPAC6F6.10c", "Q09822", "SPAC20G8.05c", "Q09697", "SPAC13A11.01c", "O60167", "SPBC19F8.03c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9USS2", "SPBC557.04", "Q10172", "SPAC25G10.09c", "Q9USP6", "SPBC9B6.08", "O43001", "SPBC2G2.02", "P87320", "SPBC1718.06", "Q92352", "SPAC6G9.07c", "Q9UUJ3", "SPAC1952.16", "Q10199", "SPBC11C11.02", "species_113592", "Q9P7V2", "SPAC30.04c", "O94685", "SPBC83.01" ] }, "reaction_10754726": { "compartment": "compartment_876", "id": "reaction_10754726", "reactome": "R-SPO-8866277", "name": "AP-2 directly binds some endocytic cargo", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754388", "species_10754720" ], "products": [ "species_10754722" ], "modifiers": [ [ "species_10754724", "inhibitor" ] ], "additional_components": [ "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q92337", "SPAC9E9.12c", "O74852", "SPCC18.02", "Q9P7V2", "SPAC30.04c", "Q92337", "SPAC9E9.12c", "Q09718", "SPAC31A2.09c", "O74852", "SPCC18.02", "Q9Y7L6", "SPBC685.04c", "Q9P7V2", "SPAC30.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "Q9C0W7", "SPBC691.03c", "Q09718", "SPAC31A2.09c", "Q9Y7L6", "SPBC685.04c", "O43079", "SPBC947.02", "O43005", "SPBC2G2.06c", "species_9648300", "Q9C0W7", "SPBC691.03c" ] }, "reaction_10749915": { "compartment": "compartment_12045", "id": "reaction_10749915", "reactome": "R-SPO-5694522", "name": "Inner coat assembly and cargo binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737349", "species_10737439", "species_10737371" ], "products": [ "species_10737373" ], "modifiers": [], "additional_components": [ "Q01475", "SPBC31F10.06c", "species_29438", "O74873", "SPCC31H12.07", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q9USS7", "SPBC4.03c", "O13644", "SPBC8D2.14c", "O74873", "SPCC31H12.07", "Q9P7G5", "SPAP14E8.03", "Q01475", "SPBC31F10.06c", "Q9UUI5", "SPAC22F8.08", "Q9USS7", "SPBC4.03c", "species_29438" ] }, "reaction_10755587": { "compartment": "compartment_262783", "id": "reaction_10755587", "reactome": "R-SPO-8876454", "name": "DENND3 exchanges GTP for GDP on RAB12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755574" ], "products": [ "species_10755437", "species_10755582", "species_29420" ], "modifiers": [ [ "species_10755584", "catalyst" ] ], "additional_components": [ "species_29420", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "species_29438", "Q9Y7Q7", "SPCC297.05" ] }, "reaction_10755519": { "compartment": "compartment_263163", "id": "reaction_10755519", "reactome": "R-SPO-8876190", "name": "RAB8 GEFs exchange GTP for GDP on RAB8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10755502" ], "products": [ "species_10755437", "species_10755514", "species_29420" ], "modifiers": [ [ "species_10755516", "catalyst" ] ], "additional_components": [ "species_29420", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "Q10305", "SPAC22H10.12c", "O60112", "SPBC15C4.03", "P17609", "SPAC9E9.07c", "O13876", "SPAC1B3.11c", "species_29438", "O13930", "SPAC23C4.10", "C6Y4C9", "SPCC1183.12" ] }, "reaction_10752787": { "compartment": "compartment_6791047", "id": "reaction_10752787", "reactome": "R-SPO-6807872", "name": "Active ARF recruits coatomer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752741", "species_10752783" ], "products": [ "species_10752785" ], "modifiers": [], "additional_components": [ "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "species_29438", "Q10491", "SPAC26F1.01", "Q09857", "SPAC29E6.03c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "O42937", "SPBC16C6.13c", "O13690", "SPBC211.03c", "P87140", "SPAC57A7.10c", "O74767", "SPBC24C6.05", "species_29438", "Q10491", "SPAC26F1.01", "O42937", "SPBC16C6.13c", "Q9P7R8", "SPBC211.03c", "Q96WV5", "SPBPJ4664.04", "O13817", "SPAC19A8.01c", "Q9UUF7", "SPBC146.14c", "O74891", "SPCC576.07", "P36579", "SPBC4F6.18c", "P11620", "SPBC1703.10", "Q09857", "SPAC29E6.03c" ] }, "reaction_10754708": { "compartment": "compartment_70101", "id": "reaction_10754708", "reactome": "R-SPO-8866275", "name": "UBQLNs bind UIM-containing adaptor proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754684", "species_10754704" ], "products": [ "species_10754706" ], "modifiers": [], "additional_components": [ "Q10169", "SPBC3B8.05", "O42967", "SPBC1E8.02", "Q9USZ7", "SPBC11G11.02c", "O74423", "SPCC162.07", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "P78813", "SPCC794.11c", "O94685", "SPBC83.01", "Q9USZ7", "SPBC11G11.02c", "Q10169", "SPBC3B8.05", "O74423", "SPCC162.07", "Q9HGL2", "SPBC800.10c", "O42967", "SPBC1E8.02", "Q10172", "SPAC25G10.09c", "P78813", "SPCC794.11c", "O94685", "SPBC83.01" ] }, "reaction_10735482": { "compartment": "compartment_7660", "id": "reaction_10735482", "reactome": "R-SPO-174110", "name": "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10735478" ], "products": [ "species_113550", "species_10735480" ], "modifiers": [ [ "species_10729577", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "SPAC24H6.05" ] }, "reaction_10729374": { "compartment": "compartment_7660", "id": "reaction_10729374", "reactome": "R-SPO-68950", "name": "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_30187", "species_29604", "species_29892", "species_10728770" ], "products": [ "species_10729371" ], "modifiers": [ [ "species_10728742", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c" ] }, "reaction_10733290": { "compartment": "compartment_70101", "id": "reaction_10733290", "reactome": "R-SPO-75825", "name": "Proteasome mediated degradation of Cyclin D1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733288" ], "products": [ "species_10729165" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P10815", "SPBC582.03", "P0C8R3", "SPAC589.10c", "P25009", "SPBC19F5.01c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10735822": { "compartment": "compartment_7660", "id": "reaction_10735822", "reactome": "R-SPO-187948", "name": "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10735523" ], "products": [ "species_113582", "species_10735525" ], "modifiers": [ [ "species_10728937", "catalyst" ] ], "additional_components": [ "SPAC144.13c", "SPAC144.13c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10735825": { "compartment": "compartment_7660", "id": "reaction_10735825", "reactome": "R-SPO-187949", "name": "CAK-mediated phosphorylation of Cyclin A:Cdk2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10735480" ], "products": [ "species_113582", "species_10728937" ], "modifiers": [ [ "species_10732457", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07" ] }, "reaction_10728773": { "compartment": "compartment_7660", "id": "reaction_10728773", "reactome": "R-SPO-68913", "name": "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10728768" ], "products": [ "species_10728764", "species_10728770" ], "modifiers": [ [ "species_10728768", "catalyst" ] ], "additional_components": [ "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "P28040", "SPAC3H5.06c", "O14215", "SPAC6B12.10c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O74761", "SPBC17D11.06", "O74946", "SPCC553.09c", "O94263", "SPBP8B7.14c", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10733284": { "compartment": "compartment_13231", "id": "reaction_10733284", "reactome": "R-SPO-75822", "name": "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733270" ], "products": [ "species_10733282" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10733286": { "compartment": "compartment_13231", "id": "reaction_10733286", "reactome": "R-SPO-75823", "name": "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733266" ], "products": [ "species_10733278" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c" ] }, "reaction_10735527": { "compartment": "compartment_13231", "id": "reaction_10735527", "reactome": "R-SPO-174273", "name": "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735466" ], "products": [ "species_10735480" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10735468": { "compartment": "compartment_70101", "id": "reaction_10735468", "reactome": "R-SPO-174054", "name": "Formation of Cyclin A:Cdk2 complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735434", "species_10729541" ], "products": [ "species_10735466" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "SPBC11B10.09", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10740250": { "compartment": "compartment_70101", "id": "reaction_10740250", "reactome": "R-SPO-549192", "name": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76103", "species_75967" ], "products": [ "species_76194", "species_549167" ], "modifiers": [ [ "species_10740247", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10733412": { "compartment": "compartment_70101", "id": "reaction_10733412", "reactome": "R-SPO-75899", "name": "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_76108" ], "products": [ "species_76103", "species_29372" ], "modifiers": [ [ "species_10733405", "catalyst" ] ], "additional_components": [ "SPAC1952.13" ] }, "reaction_10752220": { "compartment": "compartment_12045", "id": "reaction_10752220", "reactome": "R-SPO-6800334", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6800352", "species_1500578" ], "products": [ "species_76194", "species_76103" ], "modifiers": [ [ "species_10752213", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10735159": { "compartment": "compartment_70101", "id": "reaction_10735159", "reactome": "R-SPO-165162", "name": "Phosphorylation of TSC2 by PKB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735151" ], "products": [ "species_29370", "species_10735156" ], "modifiers": [ [ "species_10733746", "catalyst" ] ], "additional_components": [ "SPAC630.13c", "SPAC630.13c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c" ] }, "reaction_10735185": { "compartment": "compartment_17938", "id": "reaction_10735185", "reactome": "R-SPO-165195", "name": "GTP loading by Rheb", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10735181" ], "products": [ "species_29420", "species_10735183" ], "modifiers": [], "additional_components": [ "species_29420", "O94363", "SPBC428.16c", "species_29438", "O94363", "SPBC428.16c" ] }, "reaction_10738133": { "compartment": "compartment_70101", "id": "reaction_10738133", "reactome": "R-SPO-380930", "name": "Phosphorylated AMPK binds AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736802", "species_76577" ], "products": [ "species_10738128" ], "modifiers": [], "additional_components": [ "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10735204": { "compartment": "compartment_70101", "id": "reaction_10735204", "reactome": "R-SPO-165726", "name": "Phosphorylation of Ribosomal protein S6 by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731629", "species_113592" ], "products": [ "species_29370", "species_10735201" ], "modifiers": [ [ "species_10735194", "catalyst" ] ], "additional_components": [ "SPAPB1E7.12", "SPAPB1E7.12", "SPCC4G3.08" ] }, "reaction_10757820": { "compartment": "compartment_70101", "id": "reaction_10757820", "reactome": "R-SPO-9679044", "name": "FKBP1A binds sirolimus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757816", "species_9678687" ], "products": [ "species_10757818" ], "modifiers": [], "additional_components": [ "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c", "species_9678687", "Q10175", "SPAC27F1.06c", "O42993", "SPBC839.17c" ] }, "reaction_10738131": { "compartment": "compartment_70101", "id": "reaction_10738131", "reactome": "R-SPO-380927", "name": "p-AMPK phosphorylates TSC1:TSC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735168" ], "products": [ "species_29370", "species_10738126" ], "modifiers": [ [ "species_10738128", "catalyst" ] ], "additional_components": [ "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10735211": { "compartment": "compartment_70101", "id": "reaction_10735211", "reactome": "R-SPO-165766", "name": "Phosphorylation and activation of eIF4G by activated S6K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10731799" ], "products": [ "species_29370", "species_10735209" ], "modifiers": [ [ "species_10735194", "catalyst" ] ], "additional_components": [ "SPAC17C9.03", "SPAC17C9.03", "SPCC4G3.08" ] }, "reaction_10735174": { "compartment": "compartment_70101", "id": "reaction_10735174", "reactome": "R-SPO-165182", "name": "Phosphorylation of complexed TSC2 by PKB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10735168" ], "products": [ "species_29370", "species_10735172" ], "modifiers": [ [ "species_10733746", "catalyst" ] ], "additional_components": [ "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c", "Q10364", "SPAC22E12.14c", "species_179838", "P50530", "SPAC1B9.02c" ] }, "reaction_10746540": { "compartment": "compartment_70101", "id": "reaction_10746540", "reactome": "R-SPO-5653957", "name": "Rag dimer formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746523", "species_10746536" ], "products": [ "species_10746538" ], "modifiers": [], "additional_components": [ "O74824", "SPBC337.13c", "species_29438", "species_29420", "O74544", "SPCC777.05", "species_29420", "O74544", "SPCC777.05", "O74824", "SPBC337.13c", "species_29438" ] }, "reaction_10741434": { "compartment": "compartment_70101", "id": "reaction_10741434", "reactome": "R-SPO-984606", "name": "Kinesin-5 is a homotetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741400" ], "products": [ "species_10741402" ], "modifiers": [], "additional_components": [ "SPAC25G10.07c", "P24339", "SPAC25G10.07c" ] }, "reaction_10753183": { "compartment": "compartment_17951", "id": "reaction_10753183", "reactome": "R-SPO-6810076", "name": "DDO oxidizes D-Asp to OA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6810061", "species_141343", "species_113535" ], "products": [ "species_389843", "species_6810070", "species_113575" ], "modifiers": [ [ "species_10753180", "catalyst" ] ], "additional_components": [ "Q9Y7N4", "SPCC1450.07c", "species_113596" ] }, "reaction_10749687": { "compartment": "compartment_5460", "id": "reaction_10749687", "reactome": "R-SPO-5694018", "name": "DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113526", "species_10749674" ], "products": [ "species_29362", "species_113529", "species_10749657" ], "modifiers": [ [ "species_10749684", "catalyst" ] ], "additional_components": [ "CHEBI:50746", "Q9HDV9", "SPBP19A11.01", "SPBP19A11.01", "O00087", "SPAC1002.09c", "species_113596" ] }, "reaction_10749682": { "compartment": "compartment_5460", "id": "reaction_10749682", "reactome": "R-SPO-5693977", "name": "AMT transfers NH2CH2 from GCSH:SAMDLL to THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749661", "species_200671" ], "products": [ "species_5693984", "species_10749674", "species_5693978" ], "modifiers": [ [ "species_10749679", "catalyst" ] ], "additional_components": [ "CHEBI:14949", "Q9HDV9", "SPBP19A11.01", "CHEBI:50746", "Q9HDV9", "SPBP19A11.01", "SPAC31G5.14" ] }, "reaction_10750347": { "compartment": "compartment_5460", "id": "reaction_10750347", "reactome": "R-SPO-6784224", "name": "PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6784215" ], "products": [ "species_6784241" ], "modifiers": [ [ "species_10750344", "catalyst" ] ], "additional_components": [ "O74524", "SPCC70.03c", "species_113596" ] }, "reaction_10738379": { "compartment": "compartment_17951", "id": "reaction_10738379", "reactome": "R-SPO-389842", "name": "HAO1 tetramer oxidizes glycolate to glyoxylate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389822", "species_113535" ], "products": [ "species_389678", "species_113575" ], "modifiers": [ [ "species_10738376", "catalyst" ] ], "additional_components": [ "species_73524", "Q9HDX2", "SPAPB1A11.03" ] }, "reaction_10738367": { "compartment": "compartment_17951", "id": "reaction_10738367", "reactome": "R-SPO-389821", "name": "glycine + O2 => glyoxylate + H2O2 + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193446", "species_141343", "species_113535" ], "products": [ "species_389678", "species_389843", "species_113575" ], "modifiers": [ [ "species_10738364", "catalyst" ] ], "additional_components": [ "Q9Y7N4", "SPCC1450.07c", "species_113596" ] }, "reaction_10751187": { "compartment": "compartment_5460", "id": "reaction_10751187", "reactome": "R-SPO-6793591", "name": "LIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6793610", "species_2162265", "species_10751177" ], "products": [ "species_6793613", "species_379705", "species_10749657" ], "modifiers": [ [ "species_10751184", "catalyst" ] ], "additional_components": [ "SPBP19A11.01", "SPBP19A11.01", "O13642", "SPBC8D2.15", "CHEBI:49883" ] }, "reaction_10749672": { "compartment": "compartment_5460", "id": "reaction_10749672", "reactome": "R-SPO-5693967", "name": "PXLP-K754-GLDC dimer decarboxylates Gly", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159549", "species_10749657" ], "products": [ "species_10749661", "species_29376" ], "modifiers": [ [ "species_10749669", "catalyst" ] ], "additional_components": [ "SPBP19A11.01", "CHEBI:14949", "Q9HDV9", "SPBP19A11.01", "Q09785", "SPAC13G6.06c" ] }, "reaction_10750350": { "compartment": "compartment_5460", "id": "reaction_10750350", "reactome": "R-SPO-6784393", "name": "PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587", "species_6784236" ], "products": [ "species_6784229", "species_113553" ], "modifiers": [ [ "species_10729968", "catalyst" ] ], "additional_components": [ "O94320", "SPBC725.01" ] }, "reaction_10738382": { "compartment": "compartment_17951", "id": "reaction_10738382", "reactome": "R-SPO-389862", "name": "Conversion of glyoxylate to oxalate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_389678", "species_141343", "species_113535" ], "products": [ "species_389819", "species_113575" ], "modifiers": [ [ "species_10738376", "catalyst" ] ], "additional_components": [ "species_73524", "Q9HDX2", "SPAPB1A11.03" ] }, "reaction_10751156": { "compartment": "compartment_5460", "id": "reaction_10751156", "reactome": "R-SPO-6792572", "name": "LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751146", "species_10749657" ], "products": [ "species_10749659", "species_10751148" ], "modifiers": [ [ "species_10751153", "catalyst" ] ], "additional_components": [ "O94681", "SPBC776.15c", "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "CHEBI:17460", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "O74378", "SPBC3H7.03c", "species_113596", "SPBP19A11.01", "SPBP19A11.01", "O94681", "SPBC776.15c", "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "CHEBI:17460", "O74378", "SPBC3H7.03c", "species_113596", "SPBC17A3.09c" ] }, "reaction_10749950": { "compartment": "compartment_5460", "id": "reaction_10749950", "reactome": "R-SPO-5696408", "name": "PXLP-K278-PHYKPL tetramer hydrolyses 5PHL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_5696409" ], "products": [ "species_113556", "species_113548", "species_5693978" ], "modifiers": [ [ "species_10749947", "catalyst" ] ], "additional_components": [ "Q9US34", "SPAC1039.07c" ] }, "reaction_10737977": { "compartment": "compartment_70101", "id": "reaction_10737977", "reactome": "R-SPO-351948", "name": "Mitochondrial recruitment of Drp1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737973" ], "products": [ "species_10737975" ], "modifiers": [ [ "species_10737921", "catalyst" ] ], "additional_components": [ "SPAC767.01c", "SPAC767.01c", "SPAC9E9.04" ] }, "reaction_10754771": { "compartment": "compartment_70616", "id": "reaction_10754771", "reactome": "R-SPO-8867344", "name": "OMA1 hydrolyses OPA1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754747", "species_113521" ], "products": [ "species_10754763", "species_10754755" ], "modifiers": [ [ "species_10754768", "catalyst" ] ], "additional_components": [ "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "P87320", "SPBC1718.06", "Q09748", "SPBC12C2.08", "Q9URZ5", "SPAC767.01c", "SPAP14E8.04" ] }, "reaction_10747046": { "compartment": "compartment_70101", "id": "reaction_10747046", "reactome": "R-SPO-5675470", "name": "BIRC2/3 (cIAP1/2) is autoubiquitinated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737150", "species_10747036" ], "products": [ "species_10747039" ], "modifiers": [ [ "species_10737150", "catalyst" ] ], "additional_components": [ "SPCC962.02c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPCC962.02c", "SPCC962.02c" ] }, "reaction_10752633": { "compartment": "compartment_70101", "id": "reaction_10752633", "reactome": "R-SPO-6805811", "name": "Release of SEPT4 from mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752617" ], "products": [ "species_10752631" ], "modifiers": [], "additional_components": [ "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11", "Q09883", "SPCC188.12", "P48010", "SPAC24C9.15c", "P48008", "SPBC16A3.01", "O60165", "SPBC19F8.01c", "P48009", "SPAC9G1.11c", "O36023", "SPAC4F10.11" ] }, "reaction_10737755": { "compartment": "compartment_7660", "id": "reaction_10737755", "reactome": "R-SPO-266204", "name": "Association of HMGB1/HMGB2 with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737751", "species_29428" ], "products": [ "species_10737753" ], "modifiers": [], "additional_components": [ "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c", "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c" ] }, "reaction_10737971": { "compartment": "compartment_13231", "id": "reaction_10737971", "reactome": "R-SPO-351947", "name": "Nuclear translocation of catalytic domain of Mst3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737945" ], "products": [ "species_10737969" ], "modifiers": [], "additional_components": [ "Q10447", "SPAC12B10.14c", "O75011", "SPBC17F3.02", "O14047", "SPAC2C4.14c", "O14305", "SPAC9G1.09", "Q10447", "SPAC12B10.14c", "O75011", "SPBC17F3.02", "O14047", "SPAC2C4.14c", "O14305", "SPAC9G1.09" ] }, "reaction_10757583": { "compartment": "compartment_70101", "id": "reaction_10757583", "reactome": "R-SPO-9641096", "name": "Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757575", "species_10757579" ], "products": [ "species_10757581" ], "modifiers": [], "additional_components": [ "SPAC22E12.03c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10757601": { "compartment": "compartment_70101", "id": "reaction_10757601", "reactome": "R-SPO-9641111", "name": "Parkin transfers Ub to misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757581" ], "products": [ "species_10757599" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10757649": { "compartment": "compartment_18667", "id": "reaction_10757649", "reactome": "R-SPO-9646685", "name": "Aggresome dissociates from dynein and microtubule", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757641" ], "products": [ "species_10757647", "species_10738115", "species_10757627" ], "modifiers": [], "additional_components": [ "P04689", "SPBC800.05c", "Q92337", "SPAC9E9.12c", "Q9P3W4", "SPAC458.04c", "Q10356", "SPAC22E12.03c", "P05219", "SPBC26H8.07c", "species_29438", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c", "species_29420", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9P7V2", "SPAC30.04c", "P04688", "SPBC16A3.15c", "O13290", "SPAC1093.06c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04", "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "Q9P3W4", "SPAC458.04c", "O13290", "SPAC1093.06c", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c" ] }, "reaction_10757603": { "compartment": "compartment_70101", "id": "reaction_10757603", "reactome": "R-SPO-9641127", "name": "Ub:misfolded proteins polymerize to PolyUb:misfolded proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757599" ], "products": [ "species_10757592" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10757631": { "compartment": "compartment_70101", "id": "reaction_10757631", "reactome": "R-SPO-9646348", "name": "PolyUb-Misfolded Proteins:HDAC6 bind dynein motor", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757610", "species_10757627" ], "products": [ "species_10757629" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04", "Q9P3W4", "SPAC458.04c", "O13290", "SPAC1093.06c", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c", "P0CH07", "SPAC1805.12c", "Q92337", "SPAC9E9.12c", "P0C016", "SPAC6G10.11c", "Q9P3W4", "SPAC458.04c", "P0C8R3", "SPAC589.10c", "Q10356", "SPAC22E12.03c", "Q9P7V2", "SPAC30.04c", "O13290", "SPAC1093.06c", "Q9UR05", "SPAC926.07c", "O94518", "SPBC646.17c", "P56523", "SPBC800.03", "P0CH06", "SPAC11G7.04" ] }, "reaction_10730221": { "compartment": "compartment_70101", "id": "reaction_10730221", "reactome": "R-SPO-71146", "name": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71112" ], "products": [ "species_29356", "species_71129" ], "modifiers": [ [ "species_10730218", "catalyst" ] ], "additional_components": [ "O42658", "SPAC27D7.04" ] }, "reaction_10740374": { "compartment": "compartment_70101", "id": "reaction_10740374", "reactome": "R-SPO-893593", "name": "phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29502", "species_29398" ], "products": [ "species_893599", "species_29432" ], "modifiers": [ [ "species_10740371", "catalyst" ] ], "additional_components": [ "O14209", "SPAC6B12.04c" ] }, "reaction_10747288": { "compartment": "compartment_5683628", "id": "reaction_10747288", "reactome": "R-SPO-5682388", "name": "Autophagosome maturation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747126" ], "products": [ "species_10747279" ], "modifiers": [ [ "species_10740430", "catalyst" ], [ "species_10747286", "catalyst" ] ], "additional_components": [ "O94272", "SPBP8B7.24c", "species_1500581", "O94272", "SPBP8B7.24c", "species_1500581", "O74422", "SPCC162.06c", "O14177", "SPAC4F8.01", "O14296", "SPAC9E9.14", "O94318", "SPBC215.14c", "Q9P7F7", "SPAC1142.07c", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O60149", "SPBC18H10.19", "P87117", "SPAC20G8.10c" ] }, "reaction_10747194": { "compartment": "compartment_70101", "id": "reaction_10747194", "reactome": "R-SPO-5681981", "name": "ATG3 transfers LC3 from ATG7 to ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747189" ], "products": [ "species_10747191" ], "modifiers": [ [ "species_10747189", "catalyst" ] ], "additional_components": [ "O43035", "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c", "O43069", "SPBC6B1.05c", "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "O43035", "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c" ] }, "reaction_10746800": { "compartment": "compartment_70101", "id": "reaction_10746800", "reactome": "R-SPO-5672008", "name": "Thr-180 of ULK1 is phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746707" ], "products": [ "species_29370", "species_10746797" ], "modifiers": [ [ "species_10746707", "catalyst" ] ], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10757752": { "compartment": "compartment_17947", "id": "reaction_10757752", "reactome": "R-SPO-9664888", "name": "ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757718" ], "products": [ "species_10757740" ], "modifiers": [], "additional_components": [ "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10747085": { "compartment": "compartment_70101", "id": "reaction_10747085", "reactome": "R-SPO-5676229", "name": "WIPIs bind PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747081", "species_5693050" ], "products": [ "species_10747083" ], "modifiers": [], "additional_components": [ "Q9P6N1", "SPAC823.16c", "Q9HDZ7", "SPAC589.07c", "Q9P3W2", "SPAC458.06", "Q9P6N1", "SPAC823.16c", "Q9HDZ7", "SPAC589.07c", "Q9P3W2", "SPAC458.06", "species_1629751" ] }, "reaction_10756472": { "compartment": "compartment_21994", "id": "reaction_10756472", "reactome": "R-SPO-8959571", "name": "LC3 binds the autophagosome membrane Atg5-Atg12 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745146", "species_10756468" ], "products": [ "species_10756470" ], "modifiers": [], "additional_components": [ "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c", "O94272", "SPBP8B7.24c", "O14020", "SPAC29A4.17c", "O94272", "SPBP8B7.24c", "Q9US24", "SPAC1783.06c", "O14020", "SPAC29A4.17c", "O74971", "SPBC4B4.10c" ] }, "reaction_10747385": { "compartment": "compartment_70101", "id": "reaction_10747385", "reactome": "R-SPO-5682690", "name": "ATG10 dissociates from ATG12:ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747383" ], "products": [ "species_10747381", "species_10747137" ], "modifiers": [], "additional_components": [ "Q9US24", "SPAC1783.06c", "Q9UTD5", "SPAC227.04", "O74971", "SPBC4B4.10c", "SPAC227.04", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c" ] }, "reaction_10756095": { "compartment": "compartment_70101", "id": "reaction_10756095", "reactome": "R-SPO-8948039", "name": "FUNDC1 is phosphorylated by CK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756090", "species_113592" ], "products": [ "species_29370", "species_10756093" ], "modifiers": [ [ "species_10743403", "catalyst" ] ], "additional_components": [ "SPAC29A4.17c", "SPAC29A4.17c", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11" ] }, "reaction_10746802": { "compartment": "compartment_70101", "id": "reaction_10746802", "reactome": "R-SPO-5672011", "name": "p-AMPK:AMP binds the ULK complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746699", "species_10738128" ], "products": [ "species_10746701" ], "modifiers": [], "additional_components": [ "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O36019", "SPAC4F10.07c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O74536", "SPCC74.03c", "O36019", "SPAC4F10.07c", "P78789", "SPCC1919.03c" ] }, "reaction_10747172": { "compartment": "compartment_70101", "id": "reaction_10747172", "reactome": "R-SPO-5679239", "name": "ULK complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747055" ], "products": [ "species_10742300" ], "modifiers": [], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "Q9Y7T4", "SPCC63.08c", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10747484": { "compartment": "compartment_70101", "id": "reaction_10747484", "reactome": "R-SPO-5683588", "name": "ATG10 transfers ATG12 from ATG10 to ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747214" ], "products": [ "species_10747383" ], "modifiers": [], "additional_components": [ "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c", "Q9US24", "SPAC1783.06c", "Q9UTD5", "SPAC227.04", "O74971", "SPBC4B4.10c" ] }, "reaction_10747216": { "compartment": "compartment_70101", "id": "reaction_10747216", "reactome": "R-SPO-5682010", "name": "ATG10:ATG12 binds ATG5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747210", "species_10747212" ], "products": [ "species_10747214" ], "modifiers": [], "additional_components": [ "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c", "SPBC4B4.10c", "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c" ] }, "reaction_10757705": { "compartment": "compartment_70101", "id": "reaction_10757705", "reactome": "R-SPO-9664850", "name": "ATM binds PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757061", "species_10757701" ], "products": [ "species_10757703" ], "modifiers": [], "additional_components": [ "SPBC725.07", "SPCC23B6.03c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10747180": { "compartment": "compartment_70101", "id": "reaction_10747180", "reactome": "R-SPO-5681980", "name": "ATG12 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747176", "species_10747132" ], "products": [ "species_10747178" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "SPAC1783.06c", "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c" ] }, "reaction_10756108": { "compartment": "compartment_17906", "id": "reaction_10756108", "reactome": "R-SPO-8948146", "name": "FUNDC1 is phosphorylated by ULK1 at Ser17", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756090", "species_113592" ], "products": [ "species_29370", "species_10756105" ], "modifiers": [ [ "species_10756097", "catalyst" ] ], "additional_components": [ "SPAC29A4.17c", "SPAC29A4.17c", "SPCC63.08c" ] }, "reaction_10746710": { "compartment": "compartment_70101", "id": "reaction_10746710", "reactome": "R-SPO-5665868", "name": "AMPK (complex) phosphorylates ULK1 (complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746701", "species_113592" ], "products": [ "species_29370", "species_10746707" ], "modifiers": [ [ "species_10746701", "catalyst" ] ], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O74536", "SPCC74.03c", "O36019", "SPAC4F10.07c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O74536", "SPCC74.03c", "O36019", "SPAC4F10.07c", "P78789", "SPCC1919.03c" ] }, "reaction_10757750": { "compartment": "compartment_70101", "id": "reaction_10757750", "reactome": "R-SPO-9664883", "name": "ATM:PEX5 translocates from cytosol to peroxisomal membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757703" ], "products": [ "species_10757709" ], "modifiers": [], "additional_components": [ "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10757720": { "compartment": "compartment_17947", "id": "reaction_10757720", "reactome": "R-SPO-9664862", "name": "ATM dimer:PEX5 phosphorylates PEX5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757711" ], "products": [ "species_10757718" ], "modifiers": [], "additional_components": [ "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10747174": { "compartment": "compartment_70101", "id": "reaction_10747174", "reactome": "R-SPO-5679266", "name": "Beclin-1 complex translocates to the ER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742261" ], "products": [ "species_10747165" ], "modifiers": [], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O42862", "SPAC25A8.02", "P87117", "SPAC20G8.10c" ] }, "reaction_10747146": { "compartment": "compartment_70101", "id": "reaction_10747146", "reactome": "R-SPO-5678490", "name": "ATG16L1 complex transfers LC3 from ATG3 to PE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747124", "species_5681998" ], "products": [ "species_10747128", "species_10747126" ], "modifiers": [ [ "species_10747143", "catalyst" ] ], "additional_components": [ "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "species_1500581", "species_6809774", "Q9HDZ7", "SPAC589.07c", "Q9US24", "SPAC1783.06c", "O74971", "SPBC4B4.10c" ] }, "reaction_10756099": { "compartment": "compartment_17906", "id": "reaction_10756099", "reactome": "R-SPO-8948136", "name": "ULK1 Translocates to the mitochondria", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746691" ], "products": [ "species_10756097" ], "modifiers": [], "additional_components": [ "SPCC63.08c", "SPCC63.08c" ] }, "reaction_10747268": { "compartment": "compartment_12045", "id": "reaction_10747268", "reactome": "R-SPO-5682385", "name": "The phagophore extends from the PIP3-enriched structure", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746809" ], "products": [ "species_10747259" ], "modifiers": [ [ "species_10747264", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O42862", "SPAC25A8.02", "P87117", "SPAC20G8.10c", "SPBC15D4.07c" ] }, "reaction_10747170": { "compartment": "compartment_70101", "id": "reaction_10747170", "reactome": "R-SPO-5679206", "name": "MTMR14, MTMR3 dephosphorylate PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676030" ], "products": [ "species_426639" ], "modifiers": [ [ "species_10742434", "catalyst" ] ], "additional_components": [ "SPAC19A8.03" ] }, "reaction_10747218": { "compartment": "compartment_70101", "id": "reaction_10747218", "reactome": "R-SPO-5682011", "name": "LC3 binds ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747110", "species_10747176" ], "products": [ "species_10747187" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "O43069", "SPBC6B1.05c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c" ] }, "reaction_10747486": { "compartment": "compartment_70101", "id": "reaction_10747486", "reactome": "R-SPO-5683593", "name": "ATG7:ATG3:LC3 dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747191" ], "products": [ "species_10747176", "species_10747124" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c", "O43069", "SPBC6B1.05c", "O43035", "SPBC3B9.06c", "O94272", "SPBP8B7.24c" ] }, "reaction_10757748": { "compartment": "compartment_17947", "id": "reaction_10757748", "reactome": "R-SPO-9664880", "name": "MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747112", "species_10757744" ], "products": [ "species_10757746" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "Q9P792", "SPBP35G2.11c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "Q9P792", "SPBP35G2.11c", "O94272", "SPBP8B7.24c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10756474": { "compartment": "compartment_70101", "id": "reaction_10756474", "reactome": "R-SPO-8959573", "name": "Phosphorylated FUNDC1 links damaged mitochondria to LC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747110", "species_10756105" ], "products": [ "species_10756468" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "SPAC29A4.17c", "O94272", "SPBP8B7.24c", "O14020", "SPAC29A4.17c" ] }, "reaction_10747167": { "compartment": "compartment_70101", "id": "reaction_10747167", "reactome": "R-SPO-5679205", "name": "ULK1 phosphorylates Beclin-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10747165" ], "products": [ "species_29370", "species_10746809" ], "modifiers": [ [ "species_10742300", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "O42862", "SPAC25A8.02", "P87117", "SPAC20G8.10c", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10747524": { "compartment": "compartment_70101", "id": "reaction_10747524", "reactome": "R-SPO-5683925", "name": "ULK1 is dephosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747522" ], "products": [ "species_10746699", "species_29372" ], "modifiers": [], "additional_components": [ "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "Q9Y7T4", "SPCC63.08c", "O36019", "SPAC4F10.07c" ] }, "reaction_10747431": { "compartment": "compartment_70101", "id": "reaction_10747431", "reactome": "R-SPO-5682896", "name": "LC3:ATG7 dimer binds ATG3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747128", "species_10747187" ], "products": [ "species_10747189" ], "modifiers": [], "additional_components": [ "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c", "O43035", "SPBC3B9.06c", "O43069", "SPBC6B1.05c", "O94272", "SPBP8B7.24c" ] }, "reaction_10757731": { "compartment": "compartment_17947", "id": "reaction_10757731", "reactome": "R-SPO-9664879", "name": "ATM:PEX5 binds ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757707", "species_10757709" ], "products": [ "species_10757711" ], "modifiers": [ [ "species_1250243", "catalyst" ] ], "additional_components": [ "SPCC23B6.03c", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07", "O74630", "SPCC23B6.03c", "O94325", "SPBC725.07" ] }, "reaction_10746812": { "compartment": "compartment_12045", "id": "reaction_10746812", "reactome": "R-SPO-5672012", "name": "Beclin-1 complex phosphorylates PtdIns", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_426639" ], "products": [ "species_5676030", "species_29370" ], "modifiers": [ [ "species_10746809", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02" ] }, "reaction_10747429": { "compartment": "compartment_70101", "id": "reaction_10747429", "reactome": "R-SPO-5682893", "name": "ATG12:ATG7:CysO572-ATG7 binds ATG10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747425", "species_10747381" ], "products": [ "species_10747427" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c", "SPAC227.04", "O43069", "SPBC6B1.05c", "Q9UTD5", "SPAC227.04", "Q9US24", "SPAC1783.06c" ] }, "reaction_10742303": { "compartment": "compartment_70101", "id": "reaction_10742303", "reactome": "R-SPO-1632857", "name": "ULK1 phosphorylates AMBRA1:BECN1 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742263", "species_113592" ], "products": [ "species_10742269", "species_29370" ], "modifiers": [ [ "species_10742300", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "Q9UR05", "SPAC926.07c", "O42900", "SPBC119.07", "P50520", "SPAC458.05", "Q9UR05", "SPAC926.07c", "P87117", "SPAC20G8.10c", "O42862", "SPAC25A8.02", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10747058": { "compartment": "compartment_70101", "id": "reaction_10747058", "reactome": "R-SPO-5675868", "name": "ULK1 phosphorylates ATG13 and RB1CC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746797", "species_113592" ], "products": [ "species_29370", "species_10747055" ], "modifiers": [ [ "species_10746797", "catalyst" ] ], "additional_components": [ "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "O14261", "SPAC7D4.04", "Q9Y7T4", "SPCC63.08c", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "O13945", "SPAC23H4.02", "Q10343", "SPAC1556.08c", "Q9Y7T4", "SPCC63.08c", "O14261", "SPAC7D4.04", "O13978", "SPAC25H1.03", "O36019", "SPAC4F10.07c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10757729": { "compartment": "compartment_17947", "id": "reaction_10757729", "reactome": "R-SPO-9664867", "name": "NBR1 binds MAP1LC3B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747112", "species_10757725" ], "products": [ "species_10757727" ], "modifiers": [], "additional_components": [ "SPBP8B7.24c", "SPBP35G2.11c", "Q9P792", "SPBP35G2.11c", "O94272", "SPBP8B7.24c" ] }, "reaction_10756986": { "compartment": "compartment_70101", "id": "reaction_10756986", "reactome": "R-SPO-9020616", "name": "ATG12 forms a thioester bond with ATG7 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747178" ], "products": [ "species_10747425" ], "modifiers": [], "additional_components": [ "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c", "O43069", "SPBC6B1.05c", "Q9US24", "SPAC1783.06c" ] }, "reaction_10733817": { "compartment": "compartment_70101", "id": "reaction_10733817", "reactome": "R-SPO-109864", "name": "Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733810" ], "products": [ "species_10733776", "species_10733808" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "SPAC1D4.13", "SPAC31G5.09c" ] }, "reaction_10757664": { "compartment": "compartment_876", "id": "reaction_10757664", "reactome": "R-SPO-9647991", "name": "Palmostatin B binds RAS depalmitoylases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9647934", "species_10737221" ], "products": [ "species_10757662" ], "modifiers": [], "additional_components": [ "O42881", "SPAC8E11.04c", "species_9647934", "O42881", "SPAC8E11.04c" ] }, "reaction_10746851": { "compartment": "compartment_20699", "id": "reaction_10746851", "reactome": "R-SPO-5674373", "name": "MAP2Ks phosphorylate MAPK at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746846" ], "products": [ "species_29370", "species_10746848" ], "modifiers": [ [ "species_10746846", "catalyst" ] ], "additional_components": [ "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P10506", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10733772": { "compartment": "compartment_70101", "id": "reaction_10733772", "reactome": "R-SPO-109857", "name": "MAP2K1 binds MAPK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733756", "species_10733768" ], "products": [ "species_10733770" ], "modifiers": [], "additional_components": [ "SPAC1D4.13", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08" ] }, "reaction_10757671": { "compartment": "compartment_12045", "id": "reaction_10757671", "reactome": "R-SPO-9653514", "name": "USP17L2 deubiquitinates RCE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757666", "species_29356" ], "products": [ "species_10757668", "species_10749260" ], "modifiers": [ [ "species_10749999", "catalyst" ] ], "additional_components": [ "SPAC1687.02", "SPAC1687.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPCC1682.12c" ] }, "reaction_10746325": { "compartment": "compartment_70101", "id": "reaction_10746325", "reactome": "R-SPO-5627775", "name": "Autophosphorylation of PAK1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746306" ], "products": [ "species_29370", "species_10746322", "species_10738231" ], "modifiers": [ [ "species_10746306", "catalyst" ] ], "additional_components": [ "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c" ] }, "reaction_10757660": { "compartment": "compartment_70101", "id": "reaction_10757660", "reactome": "R-SPO-9647987", "name": "FNTB inhibitors bind FNTA:FNTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9653479", "species_10757656" ], "products": [ "species_10757658" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "LigandDisplayForward?ligandId=8030", "O13782", "SPAC17G6.04c", "O60052", "SPAPB1A10.04c", "LigandDisplayForward?ligandId=6531", "LigandDisplayForward?ligandId=8025", "LigandDisplayForward?ligandId=8024", "pubchem.compound:216453", "LigandDisplayForward?ligandId=8028", "LigandDisplayForward?ligandId=8026", "O13782", "SPAC17G6.04c", "O60052", "SPAPB1A10.04c", "LigandDisplayForward?ligandId=8030" ] }, "reaction_10746861": { "compartment": "compartment_7660", "id": "reaction_10746861", "reactome": "R-SPO-5674387", "name": "Phosphorylated MAPKs translocate into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746855" ], "products": [ "species_10746859" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10733782": { "compartment": "compartment_70101", "id": "reaction_10733782", "reactome": "R-SPO-109858", "name": "MAP2K2 binds MAPK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733778", "species_10733776" ], "products": [ "species_10733780" ], "modifiers": [], "additional_components": [ "SPAC31G5.09c", "SPAC1D4.13", "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13" ] }, "reaction_10733815": { "compartment": "compartment_70101", "id": "reaction_10733815", "reactome": "R-SPO-109863", "name": "Dissociation of p-T,Y-MAPK3:MAP2K1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733794" ], "products": [ "species_10733792", "species_10733756" ], "modifiers": [], "additional_components": [ "P27638", "SPAC31G5.09c", "P10506", "SPAC1D4.13", "Q92398", "SPBC119.08", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08", "SPAC1D4.13" ] }, "reaction_10754546": { "compartment": "compartment_7660", "id": "reaction_10754546", "reactome": "R-SPO-8856945", "name": "PP2A methylation by LCMT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754531", "species_77087" ], "products": [ "species_10754538", "species_77502" ], "modifiers": [ [ "species_10754543", "catalyst" ] ], "additional_components": [ "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "SPBP8B7.08c" ] }, "reaction_10735452": { "compartment": "compartment_13231", "id": "reaction_10735452", "reactome": "R-SPO-170159", "name": "Translocation of Cdc25 to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735448" ], "products": [ "species_10735450" ], "modifiers": [], "additional_components": [ "P06652", "SPAC24H6.05", "P06652", "SPAC24H6.05" ] }, "reaction_10754554": { "compartment": "compartment_7660", "id": "reaction_10754554", "reactome": "R-SPO-8856951", "name": "PP2A demethylation by PPME1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10754538" ], "products": [ "species_8857797", "species_10754531" ], "modifiers": [ [ "species_10754551", "catalyst" ] ], "additional_components": [ "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "SPBP4H10.17c" ] }, "reaction_10734633": { "compartment": "compartment_7660", "id": "reaction_10734633", "reactome": "R-SPO-156678", "name": "Activation of Cdc25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734625" ], "products": [ "species_29370", "species_10734628" ], "modifiers": [ [ "species_10734630", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC23C11.16" ] }, "reaction_10735444": { "compartment": "compartment_13231", "id": "reaction_10735444", "reactome": "R-SPO-170149", "name": "Translocation of active Cdc25C to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734628" ], "products": [ "species_10735442" ], "modifiers": [], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05" ] }, "reaction_10735440": { "compartment": "compartment_13231", "id": "reaction_10735440", "reactome": "R-SPO-170120", "name": "Translocation of Cdc25B to the cytoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735436" ], "products": [ "species_10735438" ], "modifiers": [], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05" ] }, "reaction_10743753": { "compartment": "compartment_70101", "id": "reaction_10743753", "reactome": "R-SPO-3002798", "name": "Cytosolic PLK1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734630" ], "products": [ "species_10734620" ], "modifiers": [], "additional_components": [ "SPAC23C11.16", "SPAC23C11.16" ] }, "reaction_10734775": { "compartment": "compartment_7660", "id": "reaction_10734775", "reactome": "R-SPO-162657", "name": "Inactivation of Myt1 kinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10734770" ], "products": [ "species_113582", "species_10734773" ], "modifiers": [ [ "species_10734620", "catalyst" ] ], "additional_components": [ "SPAC23C11.16" ] }, "reaction_10743650": { "compartment": "compartment_7660", "id": "reaction_10743650", "reactome": "R-SPO-2993780", "name": "Transfer of SUMO1 from E1 to UBE2I (UBC9)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743639", "species_10743587" ], "products": [ "species_10743647", "species_10743572" ], "modifiers": [ [ "species_10743572", "catalyst" ] ], "additional_components": [ "SPAC30D11.13", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04" ] }, "reaction_10743604": { "compartment": "compartment_7660", "id": "reaction_10743604", "reactome": "R-SPO-2990840", "name": "SENP1,2,5 proteolytically process SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743592" ], "products": [ "species_10743577" ], "modifiers": [ [ "species_10743597", "catalyst" ] ], "additional_components": [ "SPBC365.06", "SPBC365.06", "SPBC19G7.09" ] }, "reaction_10743590": { "compartment": "compartment_7660", "id": "reaction_10743590", "reactome": "R-SPO-2990833", "name": "Conjugation of SUMO1 to UBA2:SAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10743577", "species_10743572" ], "products": [ "species_10743587", "species_164121", "species_113541" ], "modifiers": [ [ "species_10743572", "catalyst" ] ], "additional_components": [ "SPBC365.06", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04", "O13351", "SPBC365.06", "O42939", "SPBC16H5.03c", "P79064", "SPAC4C5.04" ] }, "reaction_10749697": { "compartment": "compartment_70101", "id": "reaction_10749697", "reactome": "R-SPO-5694071", "name": "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29450", "species_5694074" ], "products": [ "species_5694130" ], "modifiers": [ [ "species_10749694", "catalyst" ] ], "additional_components": [ "species_442320", "Q09751", "SPBC12C2.12c" ] }, "reaction_10739914": { "compartment": "compartment_5460", "id": "reaction_10739914", "reactome": "R-SPO-450975", "name": "isocitrate <=> citrate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938" ], "products": [ "species_29654" ], "modifiers": [ [ "species_10730103", "catalyst" ] ], "additional_components": [ "SPAC24C9.06c" ] }, "reaction_10737284": { "compartment": "compartment_5460", "id": "reaction_10737284", "reactome": "R-SPO-203946", "name": "PDK isoforms phosphorylate lipo-PDH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113593", "species_10730323" ], "products": [ "species_10737268", "species_113581" ], "modifiers": [ [ "species_10737273", "catalyst" ], [ "species_113559", "catalyst" ], [ "species_29362", "catalyst" ], [ "species_113557", "inhibitor" ], [ "species_10737282", "inhibitor" ] ], "additional_components": [ "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "species_113596", "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "species_113596", "SPAC644.11c", "species_9010792", "Q9P6P9", "SPAC644.11c" ] }, "reaction_10730326": { "compartment": "compartment_5460", "id": "reaction_10730326", "reactome": "R-SPO-71397", "name": "lipo-PDH decarboxylates PYR to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113557", "species_113526" ], "products": [ "species_29376", "species_29362", "species_113559" ], "modifiers": [ [ "species_10730323", "catalyst" ] ], "additional_components": [ "species_29480", "Q09171", "SPBC30D10.13c", "O00087", "SPAC1002.09c", "O59816", "SPCC794.07", "Q10489", "SPAC26F1.03", "species_113596" ] }, "reaction_10756610": { "compartment": "compartment_5460", "id": "reaction_10756610", "reactome": "R-SPO-9011543", "name": "DCA binds PDK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9010792", "species_10737275" ], "products": [ "species_10737282" ], "modifiers": [], "additional_components": [ "SPAC644.11c", "species_9010792", "Q9P6P9", "SPAC644.11c" ] }, "reaction_10735422": { "compartment": "compartment_5460", "id": "reaction_10735422", "reactome": "R-SPO-169270", "name": "ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_10735411" ], "products": [ "species_76633", "species_10735409" ], "modifiers": [ [ "species_10735419", "catalyst" ] ], "additional_components": [ "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_31649", "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_113596", "SPAC20G8.04c" ] }, "reaction_10730165": { "compartment": "compartment_5460", "id": "reaction_10730165", "reactome": "R-SPO-70994", "name": "Succinate <=> Fumarate (with FAD redox reaction on enzyme)", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113536" ], "products": [ "species_113588" ], "modifiers": [ [ "species_10730162", "catalyst" ] ], "additional_components": [ "Q9P7X0", "SPBP23A10.16", "Q9UTJ7", "SPAC1556.02c", "O74882", "SPCC330.12c", "P21911", "SPAC140.01", "species_113596" ] }, "reaction_10730116": { "compartment": "compartment_5460", "id": "reaction_10730116", "reactome": "R-SPO-70975", "name": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113587", "species_113559" ], "products": [ "species_29374", "species_29654" ], "modifiers": [ [ "species_10730113", "catalyst" ] ], "additional_components": [ "Q10306", "SPAC6C3.04" ] }, "reaction_10757797": { "compartment": "compartment_984", "id": "reaction_10757797", "reactome": "R-SPO-9673054", "name": "PM20D1 hydrolyzes oleoyl-phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9673044", "species_109276" ], "products": [ "species_351993", "species_9673048" ], "modifiers": [ [ "species_10757792", "catalyst" ] ], "additional_components": [ "SPAC24C9.08" ] }, "reaction_10752715": { "compartment": "compartment_5460", "id": "reaction_10752715", "reactome": "R-SPO-6807826", "name": "LDHAL6B reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29362", "species_113557", "species_113529" ], "products": [ "species_113526", "species_6807616" ], "modifiers": [ [ "species_10752712", "catalyst" ] ], "additional_components": [ "SPAC186.08c" ] }, "reaction_10750305": { "compartment": "compartment_70101", "id": "reaction_10750305", "reactome": "R-SPO-6783221", "name": "HAGH hydrolyses (R)-S-LGSH to GSH and LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5694130" ], "products": [ "species_29450", "species_29708" ], "modifiers": [ [ "species_10750302", "catalyst" ] ], "additional_components": [ "species_442320", "Q9UT36", "SPAC824.07" ] }, "reaction_10730098": { "compartment": "compartment_5460", "id": "reaction_10730098", "reactome": "R-SPO-70967", "name": "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29938", "species_113526" ], "products": [ "species_113594", "species_29376", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730095", "catalyst" ], [ "species_113581", "catalyst" ] ], "additional_components": [ "O13696", "SPAC11G7.03", "species_113527", "Q9USP8", "SPBC902.05c" ] }, "reaction_10730607": { "compartment": "compartment_70101", "id": "reaction_10730607", "reactome": "R-SPO-71849", "name": "LDH tetramer reduces PYR to LACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_29398" ], "products": [ "species_29708", "species_29360" ], "modifiers": [ [ "species_10729885", "catalyst" ] ], "additional_components": [ "Q9P7P7", "SPAC186.08c" ] }, "reaction_10735414": { "compartment": "compartment_5460", "id": "reaction_10735414", "reactome": "R-SPO-169260", "name": "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735409", "species_31649" ], "products": [ "species_113596", "species_10735411" ], "modifiers": [ [ "species_10735409", "catalyst" ] ], "additional_components": [ "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_113596", "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_31649", "P78790", "SPAC27D7.06", "species_76577", "Q9UTH2", "SPAC1805.02c", "species_113596" ] }, "reaction_10739916": { "compartment": "compartment_5460", "id": "reaction_10739916", "reactome": "R-SPO-451033", "name": "(S)-Malate <=> Fumarate + H2O", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113544" ], "products": [ "species_113521", "species_113588" ], "modifiers": [ [ "species_10730133", "catalyst" ] ], "additional_components": [ "O94552", "SPCC18.18c" ] }, "reaction_10756661": { "compartment": "compartment_70101", "id": "reaction_10756661", "reactome": "R-SPO-9012374", "name": "VDAC1 transports PYR from cytosol to mitochondrial intermembrane space", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398" ], "products": [ "species_9012375" ], "modifiers": [ [ "species_10745156", "catalyst" ] ], "additional_components": [ "SPAC1635.01" ] }, "reaction_10730180": { "compartment": "compartment_5460", "id": "reaction_10730180", "reactome": "R-SPO-70997", "name": "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113548", "species_113581", "species_70958" ], "products": [ "species_29374", "species_113536", "species_113593" ], "modifiers": [ [ "species_10730177", "catalyst" ] ], "additional_components": [ "O13750", "SPAC16E8.17c", "O94415", "SPCC1620.08" ] }, "reaction_10735047": { "compartment": "compartment_70616", "id": "reaction_10735047", "reactome": "R-SPO-164651", "name": "Electron transfer from ubiquinol to cytochrome c of complex III", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76633", "species_10734930", "species_113529", "species_73663" ], "products": [ "species_76633", "species_10734928", "species_163953", "species_73663" ], "modifiers": [ [ "species_10735044", "catalyst" ] ], "additional_components": [ "P00046", "SPCC191.07", "CHEBI:38574", "P00046", "SPCC191.07", "CHEBI:38573", "Q9P7X1", "SPBP23A10.15c", "Q09154", "SPBC16H5.06", "O42932", "SPBC16C6.08c", "P05501", "SPMIT.05", "P50523", "SPAC1782.07", "O74533", "SPCC737.02c", "O59680", "SPBC29A3.18", "O94745", "SPBC18E5.12c", "O74433", "SPCC1682.01" ] }, "reaction_10729888": { "compartment": "compartment_70101", "id": "reaction_10729888", "reactome": "R-SPO-70510", "name": "LDH tetramer oxidises LACT to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29708", "species_29360" ], "products": [ "species_70106", "species_73473", "species_29398" ], "modifiers": [ [ "species_10729885", "catalyst" ] ], "additional_components": [ "Q9P7P7", "SPAC186.08c" ] }, "reaction_10756645": { "compartment": "compartment_5460", "id": "reaction_10756645", "reactome": "R-SPO-9012016", "name": "FAHD1:Zn2+ dimer hydrolyses OA to PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113587" ], "products": [ "species_29376", "species_113557" ], "modifiers": [ [ "species_10756642", "catalyst" ] ], "additional_components": [ "species_29926", "Q9P7L4", "SPBC21C3.09c" ] }, "reaction_10730328": { "compartment": "compartment_5460", "id": "reaction_10730328", "reactome": "R-SPO-71401", "name": "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113594", "species_113526" ], "products": [ "species_29376", "species_70958", "species_29362" ], "modifiers": [ [ "species_10730208", "catalyst" ] ], "additional_components": [ "O94681", "SPBC776.15c", "species_29480", "O00087", "SPAC1002.09c", "CHEBI:17460", "O74378", "SPBC3H7.03c", "species_113596" ] }, "reaction_10740353": { "compartment": "compartment_5460", "id": "reaction_10740353", "reactome": "R-SPO-880007", "name": "(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113596", "species_879997" ], "products": [ "species_113594", "species_31649" ], "modifiers": [ [ "species_10740350", "catalyst" ], [ "species_880069", "catalyst" ], [ "species_113527", "catalyst" ], [ "species_880067", "catalyst" ] ], "additional_components": [ "SPBC713.03" ] }, "reaction_10757795": { "compartment": "compartment_984", "id": "reaction_10757795", "reactome": "R-SPO-9673053", "name": "PM20D1 transforms oleoyl-phe from oleate and phe", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_351993", "species_9673048" ], "products": [ "species_9673044", "species_109276" ], "modifiers": [ [ "species_10757792", "catalyst" ] ], "additional_components": [ "SPAC24C9.08" ] }, "reaction_10736322": { "compartment": "compartment_70101", "id": "reaction_10736322", "reactome": "R-SPO-194678", "name": "CYP51A1 demethylates LNSOL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194634", "species_29368" ], "products": [ "species_29366", "species_194644", "species_29460", "species_29356" ], "modifiers": [ [ "species_10736319", "catalyst" ] ], "additional_components": [ "SPAC13A11.02c" ] }, "reaction_10742192": { "compartment": "compartment_161320", "id": "reaction_10742192", "reactome": "R-SPO-1605736", "name": "Alpha-galactosidase A removes a terminal galactose from alpha-D-galactoside oligomers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1605716", "species_1605715" ], "products": [ "species_1605601", "species_1605637" ], "modifiers": [ [ "species_10742189", "catalyst" ] ], "additional_components": [ "Q9URZ0", "SPAC869.07c" ] }, "reaction_10742202": { "compartment": "compartment_876", "id": "reaction_10742202", "reactome": "R-SPO-1606273", "name": "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10742199", "catalyst" ] ], "additional_components": [ "O74369", "SPBC32F12.01c", "species_29926" ] }, "reaction_10742308": { "compartment": "compartment_876", "id": "reaction_10742308", "reactome": "R-SPO-1640164", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_429776", "species_29356" ], "products": [ "species_429807", "species_1610735" ], "modifiers": [ [ "species_10742305", "catalyst" ] ], "additional_components": [ "SPBC725.05c" ] }, "reaction_10745892": { "compartment": "compartment_70101", "id": "reaction_10745892", "reactome": "R-SPO-5362721", "name": "RDH5,RDH11 oxidise 11cROL to 11cRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_30927" ], "products": [ "species_70106", "species_73473", "species_32737" ], "modifiers": [ [ "species_10745889", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10745878": { "compartment": "compartment_70101", "id": "reaction_10745878", "reactome": "R-SPO-5362522", "name": "ALDHs oxidise atRAL to atRA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975622", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_5334816" ], "modifiers": [ [ "species_10745875", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10745907": { "compartment": "compartment_70101", "id": "reaction_10745907", "reactome": "R-SPO-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10745904", "catalyst" ] ], "additional_components": [ "O74959", "SPCC736.13", "O13822", "SPCC736.13" ] }, "reaction_10745865": { "compartment": "compartment_70101", "id": "reaction_10745865", "reactome": "R-SPO-5362518", "name": "RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10745862", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10746047": { "compartment": "compartment_70101", "id": "reaction_10746047", "reactome": "R-SPO-5615668", "name": "AKR1C3 reduces atRAL to atROL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_975622" ], "products": [ "species_29366", "species_975599" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10745883": { "compartment": "compartment_70101", "id": "reaction_10745883", "reactome": "R-SPO-5362564", "name": "ADH1A,1C,4 oxidise atROL to atRAL in vitro", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975599", "species_29360" ], "products": [ "species_70106", "species_73473", "species_975622" ], "modifiers": [ [ "species_10745880", "catalyst" ] ], "additional_components": [ "species_442320", "P78870", "SPCC13B11.04c", "O74540", "SPCC13B11.04c" ] }, "reaction_10737563": { "compartment": "compartment_7660", "id": "reaction_10737563", "reactome": "R-SPO-212263", "name": "PRC2 trimethylates histone H3 at lysine-27", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10737551" ], "products": [ "species_10737560", "species_77502" ], "modifiers": [ [ "species_10737551", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c" ] }, "reaction_10745441": { "compartment": "compartment_7660", "id": "reaction_10745441", "reactome": "R-SPO-5220959", "name": "TDG excises 5-formylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5221062", "species_10733857" ], "products": [ "species_10733889", "species_5221065" ], "modifiers": [ [ "species_10733857", "catalyst" ] ], "additional_components": [ "SPCC965.05c", "O59825", "SPCC965.05c", "SPCC965.05c" ] }, "reaction_10745443": { "compartment": "compartment_7660", "id": "reaction_10745443", "reactome": "R-SPO-5221061", "name": "TDG excises 5-carboxylcytosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5220996", "species_10733857" ], "products": [ "species_5221064", "species_10733889" ], "modifiers": [ [ "species_10733857", "catalyst" ] ], "additional_components": [ "SPCC965.05c", "O59825", "SPCC965.05c", "SPCC965.05c" ] }, "reaction_10749501": { "compartment": "compartment_70101", "id": "reaction_10749501", "reactome": "R-SPO-5691431", "name": "PSMD14 cleaves K63-linked ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735397" ], "products": [ "species_10735395" ], "modifiers": [ [ "species_10729170", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPAC31G5.13" ] }, "reaction_10749588": { "compartment": "compartment_70101", "id": "reaction_10749588", "reactome": "R-SPO-5693061", "name": "STAMBP binds STAM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749579", "species_10749584" ], "products": [ "species_10749586" ], "modifiers": [], "additional_components": [ "O74749", "SPBC1734.08", "O94478", "SPCC1919.11", "SPAC19B12.10", "O74749", "SPBC1734.08", "Q9P371", "SPAC19B12.10", "O94478", "SPCC1919.11" ] }, "reaction_10749982": { "compartment": "compartment_70101", "id": "reaction_10749982", "reactome": "R-SPO-5696547", "name": "STAMBPL1 is a deubiquitinase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735397" ], "products": [ "species_10735395" ], "modifiers": [ [ "species_10749979", "catalyst" ], [ "species_10749586", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPAC19B12.10", "O74749", "SPBC1734.08", "Q9P371", "SPAC19B12.10", "O94478", "SPCC1919.11" ] }, "reaction_10736864": { "compartment": "compartment_876", "id": "reaction_10736864", "reactome": "R-SPO-200646", "name": "Cytosolic folate export across the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197965" ], "products": [ "species_200716" ], "modifiers": [ [ "species_10736861", "catalyst" ] ], "additional_components": [ "SPAC14C4.07" ] }, "reaction_10736856": { "compartment": "compartment_70101", "id": "reaction_10736856", "reactome": "R-SPO-200644", "name": "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_200739" ], "products": [ "species_70106", "species_29364", "species_200640" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10744081": { "compartment": "compartment_70101", "id": "reaction_10744081", "reactome": "R-SPO-3323111", "name": "Cytoslic carboxylases translocate to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743659" ], "products": [ "species_10743759" ], "modifiers": [], "additional_components": [ "Q9UUE1", "SPBC17G9.11c", "species_113527", "Q9UUE1", "SPBC17G9.11c", "species_113527" ] }, "reaction_10749713": { "compartment": "compartment_70616", "id": "reaction_10749713", "reactome": "R-SPO-5694137", "name": "PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693984", "species_113521", "species_159549" ], "products": [ "species_200671", "species_379732" ], "modifiers": [ [ "species_10749710", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c", "O13972", "SPAC24C9.12c" ] }, "reaction_10736843": { "compartment": "compartment_7660", "id": "reaction_10736843", "reactome": "R-SPO-200512", "name": "NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_200492" ], "products": [ "species_200499", "species_113541" ], "modifiers": [ [ "species_10736840", "catalyst" ] ], "additional_components": [ "species_442320", "Q9UT53", "SPAC806.06c" ] }, "reaction_10740902": { "compartment": "compartment_70101", "id": "reaction_10740902", "reactome": "R-SPO-964962", "name": "2xPDKX:2xZn2+ phosphorylates PDX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965053", "species_113592" ], "products": [ "species_29370", "species_964952" ], "modifiers": [ [ "species_10740897", "catalyst" ] ], "additional_components": [ "species_442320", "O14242", "SPAC6F6.11c" ] }, "reaction_10736380": { "compartment": "compartment_70101", "id": "reaction_10736380", "reactome": "R-SPO-196754", "name": "COASY transfers an adenylyl group from ATP to PPANT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196767", "species_113592" ], "products": [ "species_196778", "species_111294" ], "modifiers": [ [ "species_10736377", "catalyst" ] ], "additional_components": [ "SPAC1F12.08" ] }, "reaction_10736449": { "compartment": "compartment_70101", "id": "reaction_10736449", "reactome": "R-SPO-197958", "name": "FPGS-2 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_111355" ], "products": [ "species_29370", "species_197969", "species_29372" ], "modifiers": [ [ "species_10736446", "catalyst" ] ], "additional_components": [ "SPBC1709.17" ] }, "reaction_10755126": { "compartment": "compartment_70101", "id": "reaction_10755126", "reactome": "R-SPO-8869633", "name": "NMRK1 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10755112", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10743762": { "compartment": "compartment_70101", "id": "reaction_10743762", "reactome": "R-SPO-3095901", "name": "ABCC1 transports cytosolic Cbl to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_3000241", "species_29356" ], "products": [ "species_29370", "species_3000125", "species_29372" ], "modifiers": [ [ "species_10737726", "catalyst" ] ], "additional_components": [ "SPAC3F10.11c" ] }, "reaction_10736897": { "compartment": "compartment_70101", "id": "reaction_10736897", "reactome": "R-SPO-200711", "name": "MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29460", "species_197969" ], "products": [ "species_29370", "species_111353", "species_29372" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10736901": { "compartment": "compartment_70616", "id": "reaction_10736901", "reactome": "R-SPO-200720", "name": "SLC25A32 transports THF from mitochondrial matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671" ], "products": [ "species_111355" ], "modifiers": [ [ "species_10736884", "catalyst" ] ], "additional_components": [ "SPBC27B12.09c" ] }, "reaction_10736383": { "compartment": "compartment_70101", "id": "reaction_10736383", "reactome": "R-SPO-196773", "name": "COASY phosphorylates DP-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_196778" ], "products": [ "species_76194", "species_29370" ], "modifiers": [ [ "species_10736377", "catalyst" ] ], "additional_components": [ "SPAC1F12.08" ] }, "reaction_10740904": { "compartment": "compartment_70101", "id": "reaction_10740904", "reactome": "R-SPO-964970", "name": "2xPDXK:2xZn2+ phosphorylates PXL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965131", "species_113592" ], "products": [ "species_29370", "species_29390" ], "modifiers": [ [ "species_10740897", "catalyst" ] ], "additional_components": [ "species_442320", "O14242", "SPAC6F6.11c" ] }, "reaction_10744750": { "compartment": "compartment_70101", "id": "reaction_10744750", "reactome": "R-SPO-4167511", "name": "HLCS biotinylates ACACB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_10744748", "species_113592" ], "products": [ "species_111294", "species_76577", "species_10736807" ], "modifiers": [ [ "species_10743664", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527", "P78820", "SPAC56E4.04c", "species_113527", "SPBC30D10.07c" ] }, "reaction_10736866": { "compartment": "compartment_70101", "id": "reaction_10736866", "reactome": "R-SPO-200651", "name": "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_200739" ], "products": [ "species_200736", "species_197969" ], "modifiers": [ [ "species_10730229", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c" ] }, "reaction_10740888": { "compartment": "compartment_70101", "id": "reaction_10740888", "reactome": "R-SPO-947514", "name": "PXLP-K258-NFS1 transfers sulfur from cysteine onto MOCS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740872", "species_111707" ], "products": [ "species_10740877", "species_29432" ], "modifiers": [ [ "species_10740885", "catalyst" ] ], "additional_components": [ "species_442320", "Q09810", "SPAC2G11.10c", "species_442320", "Q09810", "SPAC2G11.10c", "O74351", "SPBC21D10.11c" ] }, "reaction_10740914": { "compartment": "compartment_70101", "id": "reaction_10740914", "reactome": "R-SPO-965019", "name": "2xPNPO:2xFMN oxidizes PDXP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964952", "species_29368" ], "products": [ "species_29408", "species_29390" ], "modifiers": [ [ "species_10740911", "catalyst" ] ], "additional_components": [ "Q9UTQ1", "SPAC1093.02", "species_73524" ] }, "reaction_10736894": { "compartment": "compartment_5460", "id": "reaction_10736894", "reactome": "R-SPO-200682", "name": "Mitochondrial FPGS-1 transforms THF to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_200671", "species_113593" ], "products": [ "species_113548", "species_200679", "species_113581" ], "modifiers": [ [ "species_10736891", "catalyst" ] ], "additional_components": [ "SPBC1709.17" ] }, "reaction_10736836": { "compartment": "compartment_5460", "id": "reaction_10736836", "reactome": "R-SPO-200474", "name": "NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8938083", "species_113593" ], "products": [ "species_8938090", "species_159450" ], "modifiers": [ [ "species_10736833", "catalyst" ] ], "additional_components": [ "Q9UT53", "SPAC806.06c", "species_29926" ] }, "reaction_10740900": { "compartment": "compartment_70101", "id": "reaction_10740900", "reactome": "R-SPO-964958", "name": "2xPDXK:2xZn2+ phosphorylates PXA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_964945", "species_113592" ], "products": [ "species_29370", "species_965146" ], "modifiers": [ [ "species_10740897", "catalyst" ] ], "additional_components": [ "species_442320", "O14242", "SPAC6F6.11c" ] }, "reaction_10736905": { "compartment": "compartment_70101", "id": "reaction_10736905", "reactome": "R-SPO-200735", "name": "SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736", "species_197969" ], "products": [ "species_29424", "species_200739" ], "modifiers": [ [ "species_10730229", "catalyst" ] ], "additional_components": [ "Q10104", "SPAC18G6.04c" ] }, "reaction_10736907": { "compartment": "compartment_70101", "id": "reaction_10736907", "reactome": "R-SPO-200740", "name": "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200640", "species_29356" ], "products": [ "species_111353" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10752500": { "compartment": "compartment_5460", "id": "reaction_10752500", "reactome": "R-SPO-6801456", "name": "MTHFD1L transforms 10-formyl-THF to HCOOH and THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5389850", "species_113548", "species_113581" ], "products": [ "species_200671", "species_6801451", "species_113593" ], "modifiers": [ [ "species_10750054", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16", "O43007", "SPBC2G2.08" ] }, "reaction_10736658": { "compartment": "compartment_70101", "id": "reaction_10736658", "reactome": "R-SPO-198845", "name": "CYB5A:heme reduces Asc.- to AscH-", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736644", "species_1497805" ], "products": [ "species_198816", "species_10736642" ], "modifiers": [ [ "species_10736644", "catalyst" ] ], "additional_components": [ "species_189444", "Q9USM6", "SPCC16A11.10c", "CHEBI:36144", "Q9USM6", "SPCC16A11.10c", "species_189444", "Q9USM6", "SPCC16A11.10c" ] }, "reaction_10736899": { "compartment": "compartment_70101", "id": "reaction_10736899", "reactome": "R-SPO-200718", "name": "MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200640" ], "products": [ "species_29366", "species_200739" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10743673": { "compartment": "compartment_70101", "id": "reaction_10743673", "reactome": "R-SPO-2993814", "name": "HLCS biotinylates ACACA:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_10743671", "species_113592" ], "products": [ "species_10733321", "species_111294", "species_76577" ], "modifiers": [ [ "species_10743664", "catalyst" ] ], "additional_components": [ "P78820", "SPAC56E4.04c", "species_113527", "P78820", "SPAC56E4.04c", "species_113527", "SPBC30D10.07c" ] }, "reaction_10736431": { "compartment": "compartment_70101", "id": "reaction_10736431", "reactome": "R-SPO-197235", "name": "NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_197220" ], "products": [ "species_197256", "species_111294" ], "modifiers": [ [ "species_10736428", "catalyst" ] ], "additional_components": [ "Q9UT53", "SPAC806.06c", "species_29926" ] }, "reaction_10736372": { "compartment": "compartment_70101", "id": "reaction_10736372", "reactome": "R-SPO-196753", "name": "2xPPCS ligates PPanK with Cys", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111707", "species_196786" ], "products": [ "species_196834", "species_111294", "species_76577" ], "modifiers": [ [ "species_10736369", "catalyst" ] ], "additional_components": [ "Q9USK7", "SPCC4B3.18" ] }, "reaction_10740916": { "compartment": "compartment_70101", "id": "reaction_10740916", "reactome": "R-SPO-965079", "name": "2xPNPO:2xFMN oxidizes PXAP to PXLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_965146", "species_29368", "species_29356" ], "products": [ "species_29408", "species_31633", "species_29390" ], "modifiers": [ [ "species_10740911", "catalyst" ] ], "additional_components": [ "Q9UTQ1", "SPAC1093.02", "species_73524" ] }, "reaction_10736441": { "compartment": "compartment_70101", "id": "reaction_10736441", "reactome": "R-SPO-197271", "name": "NADSYN1 hexamer amidates NAAD to NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_197256", "species_29472", "species_113592", "species_29356" ], "products": [ "species_29404", "species_111294", "species_29360", "species_76577" ], "modifiers": [ [ "species_10736438", "catalyst" ] ], "additional_components": [ "O74940", "SPCC553.02" ] }, "reaction_10743667": { "compartment": "compartment_70101", "id": "reaction_10743667", "reactome": "R-SPO-2993802", "name": "HLCS biotinylates PC:Mn2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_199207", "species_113592", "species_10743654" ], "products": [ "species_10743659", "species_111294", "species_76577" ], "modifiers": [ [ "species_10743664", "catalyst" ] ], "additional_components": [ "Q9UUE1", "SPBC17G9.11c", "species_113527", "Q9UUE1", "SPBC17G9.11c", "species_113527", "SPBC30D10.07c" ] }, "reaction_10736903": { "compartment": "compartment_876", "id": "reaction_10736903", "reactome": "R-SPO-200729", "name": "SLC46A1 transports FOLA from extracellular region to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200716" ], "products": [ "species_197965" ], "modifiers": [ [ "species_10736861", "catalyst" ] ], "additional_components": [ "SPAC14C4.07" ] }, "reaction_10752956": { "compartment": "compartment_70101", "id": "reaction_10752956", "reactome": "R-SPO-6808496", "name": "ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_111353", "species_29356" ], "products": [ "species_70106", "species_29364", "species_113528", "species_197969" ], "modifiers": [ [ "species_10752953", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10752498": { "compartment": "compartment_70101", "id": "reaction_10752498", "reactome": "R-SPO-6801342", "name": "MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6803257", "species_113592" ], "products": [ "species_70106", "species_29370", "species_200640", "species_29372" ], "modifiers": [ [ "species_10752495", "catalyst" ] ], "additional_components": [ "SPBC1703.08c" ] }, "reaction_10757959": { "compartment": "compartment_70101", "id": "reaction_10757959", "reactome": "R-SPO-9709098", "name": "DHFR dimer reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_197965" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10757956", "catalyst" ] ], "additional_components": [ "P36591", "SPCC1223.08c" ] }, "reaction_10755120": { "compartment": "compartment_70101", "id": "reaction_10755120", "reactome": "R-SPO-8869607", "name": "NMRK2 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10755117", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10750057": { "compartment": "compartment_5460", "id": "reaction_10750057", "reactome": "R-SPO-5696839", "name": "MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200671", "species_6801451", "species_113593" ], "products": [ "species_5389850", "species_113548", "species_113581" ], "modifiers": [ [ "species_10750054", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16", "O43007", "SPBC2G2.08" ] }, "reaction_10736457": { "compartment": "compartment_70101", "id": "reaction_10736457", "reactome": "R-SPO-197963", "name": "DHFR2 reduces FOLA to DHF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_197965" ], "products": [ "species_29366", "species_73604" ], "modifiers": [ [ "species_10736454", "catalyst" ] ], "additional_components": [ "SPCC1223.08c" ] }, "reaction_10755856": { "compartment": "compartment_70101", "id": "reaction_10755856", "reactome": "R-SPO-8939959", "name": "NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869353" ], "products": [ "species_111294", "species_29360" ], "modifiers": [ [ "species_10736428", "catalyst" ] ], "additional_components": [ "Q9UT53", "SPAC806.06c", "species_29926" ] }, "reaction_10736889": { "compartment": "compartment_70101", "id": "reaction_10736889", "reactome": "R-SPO-200681", "name": "FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29404", "species_200665" ], "products": [ "species_29370", "species_174404", "species_29372" ], "modifiers": [ [ "species_10736446", "catalyst" ] ], "additional_components": [ "SPBC1709.17" ] }, "reaction_10736421": { "compartment": "compartment_70101", "id": "reaction_10736421", "reactome": "R-SPO-197198", "name": "NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_29360" ], "products": [ "species_29370", "species_29366" ], "modifiers": [ [ "species_10736418", "catalyst" ] ], "additional_components": [ "species_442320", "O13863", "SPAC1B1.02c" ] }, "reaction_10755115": { "compartment": "compartment_70101", "id": "reaction_10755115", "reactome": "R-SPO-8869606", "name": "NMRK1 phosphorylates NAR to yield NAMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869365" ], "products": [ "species_70106", "species_29370", "species_197220" ], "modifiers": [ [ "species_10755112", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10736655": { "compartment": "compartment_70101", "id": "reaction_10736655", "reactome": "R-SPO-198824", "name": "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10736642" ], "products": [ "species_29360", "species_10736644" ], "modifiers": [ [ "species_10736652", "catalyst" ] ], "additional_components": [ "CHEBI:36144", "Q9USM6", "SPCC16A11.10c", "species_189444", "Q9USM6", "SPCC16A11.10c", "O74557", "SPCC970.03", "species_113596" ] }, "reaction_10736869": { "compartment": "compartment_70101", "id": "reaction_10736869", "reactome": "R-SPO-200661", "name": "MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111353" ], "products": [ "species_200640", "species_29356" ], "modifiers": [ [ "species_10736853", "catalyst" ] ], "additional_components": [ "Q8WZJ7", "SPBC839.16" ] }, "reaction_10755480": { "compartment": "compartment_17927", "id": "reaction_10755480", "reactome": "R-SPO-8875838", "name": "SLC25A19 transports ThDP from cytosol to mitochondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29480" ], "products": [ "species_8878387" ], "modifiers": [ [ "species_10755477", "catalyst" ] ], "additional_components": [ "SPBC1604.04" ] }, "reaction_10755123": { "compartment": "compartment_70101", "id": "reaction_10755123", "reactome": "R-SPO-8869627", "name": "NMRK2 phosphorylates NR to yield NMN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_8869377" ], "products": [ "species_70106", "species_29370", "species_8869353" ], "modifiers": [ [ "species_10755117", "catalyst" ] ], "additional_components": [ "SPBP22H7.06" ] }, "reaction_10736459": { "compartment": "compartment_70101", "id": "reaction_10736459", "reactome": "R-SPO-197972", "name": "DHF is reduced to tetrahydrofolate (THF)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_73604" ], "products": [ "species_29366", "species_111355" ], "modifiers": [ [ "species_10736454", "catalyst" ] ], "additional_components": [ "SPCC1223.08c" ] }, "reaction_10736879": { "compartment": "compartment_70101", "id": "reaction_10736879", "reactome": "R-SPO-200676", "name": "MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_200739" ], "products": [ "species_29366", "species_174404" ], "modifiers": [ [ "species_10736876", "catalyst" ] ], "additional_components": [ "Q10258", "SPAC56F8.10" ] }, "reaction_10752948": { "compartment": "compartment_5460", "id": "reaction_10752948", "reactome": "R-SPO-6808487", "name": "ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6808499", "species_113563", "species_113521" ], "products": [ "species_113600", "species_200679", "species_29376", "species_113529" ], "modifiers": [ [ "species_10752945", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10736666": { "compartment": "compartment_70616", "id": "reaction_10736666", "reactome": "R-SPO-199216", "name": "SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194" ], "products": [ "species_29374" ], "modifiers": [ [ "species_10736663", "catalyst" ] ], "additional_components": [ "SPAC17H9.08" ] }, "reaction_10736327": { "compartment": "compartment_70101", "id": "reaction_10736327", "reactome": "R-SPO-194698", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644" ], "products": [ "species_29366", "species_194633" ], "modifiers": [ [ "species_10736324", "catalyst" ] ], "additional_components": [ "SPBC16G5.18" ] }, "reaction_10736094": { "compartment": "compartment_70101", "id": "reaction_10736094", "reactome": "R-SPO-191352", "name": "HMGCR dimer reduces bHMG-CoA to MVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191374" ], "products": [ "species_76194", "species_29366", "species_191424" ], "modifiers": [ [ "species_10736091", "catalyst" ] ], "additional_components": [ "Q10283", "SPCC162.09c" ] }, "reaction_10736314": { "compartment": "compartment_13231", "id": "reaction_10736314", "reactome": "R-SPO-194674", "name": "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194681", "species_194688", "species_194725" ], "products": [ "species_194704", "species_194668" ], "modifiers": [ [ "species_10736311", "catalyst" ] ], "additional_components": [ "SPBC16G5.18" ] }, "reaction_10736304": { "compartment": "compartment_70101", "id": "reaction_10736304", "reactome": "R-SPO-194642", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_194735", "species_29360" ], "products": [ "species_70106", "species_73473", "species_113528", "species_194667" ], "modifiers": [ [ "species_10736301", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736084": { "compartment": "compartment_70101", "id": "reaction_10736084", "reactome": "R-SPO-191323", "name": "HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191293", "species_29356", "species_76183" ], "products": [ "species_70106", "species_76194", "species_191374" ], "modifiers": [ [ "species_10736081", "catalyst" ] ], "additional_components": [ "SPAC4F8.14c" ] }, "reaction_10736329": { "compartment": "compartment_70101", "id": "reaction_10736329", "reactome": "R-SPO-194718", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_194657" ], "products": [ "species_73473", "species_70106", "species_194661", "species_113528" ], "modifiers": [ [ "species_10736301", "catalyst" ] ], "additional_components": [ "SPBC3F6.02c" ] }, "reaction_10736076": { "compartment": "compartment_70101", "id": "reaction_10736076", "reactome": "R-SPO-191303", "name": "FDPS dimer transfers IPPP to GPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191409" ], "products": [ "species_111294", "species_191385" ], "modifiers": [ [ "species_10736073", "catalyst" ] ], "additional_components": [ "species_29926", "O14230", "SPAC6F12.13c" ] }, "reaction_10745569": { "compartment": "compartment_17957", "id": "reaction_10745569", "reactome": "R-SPO-5250531", "name": "ARV1 transports CHOL from ER membrane to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193384" ], "products": [ "species_171095" ], "modifiers": [ [ "species_10745566", "catalyst" ] ], "additional_components": [ "SPAPB1A10.15" ] }, "reaction_10736079": { "compartment": "compartment_70101", "id": "reaction_10736079", "reactome": "R-SPO-191322", "name": "FDPS dimer transfers IPPP to DMAPP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362", "species_191324" ], "products": [ "species_191409", "species_111294" ], "modifiers": [ [ "species_10736073", "catalyst" ] ], "additional_components": [ "species_29926", "O14230", "SPAC6F12.13c" ] }, "reaction_10736306": { "compartment": "compartment_70101", "id": "reaction_10736306", "reactome": "R-SPO-194669", "name": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194723", "species_29368" ], "products": [ "species_29366", "species_29356", "species_194657" ], "modifiers": [ [ "species_10736296", "catalyst" ] ], "additional_components": [ "SPAC630.08c" ] }, "reaction_10736102": { "compartment": "compartment_70101", "id": "reaction_10736102", "reactome": "R-SPO-191366", "name": "Squalene 2,3-epoxide cyclizes, forming lanosterol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191309" ], "products": [ "species_194634" ], "modifiers": [ [ "species_10736099", "catalyst" ] ], "additional_components": [ "SPAC13G7.01c" ] }, "reaction_10736134": { "compartment": "compartment_70101", "id": "reaction_10736134", "reactome": "R-SPO-191405", "name": "Two FPP molecules dimerize to form presqualene diphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191385" ], "products": [ "species_191265", "species_111294" ], "modifiers": [ [ "species_10736129", "catalyst" ] ], "additional_components": [ "P36596", "SPBC646.05c", "species_29926" ] }, "reaction_10736112": { "compartment": "compartment_70101", "id": "reaction_10736112", "reactome": "R-SPO-191380", "name": "Mevalonate is phosphorylated to mevalonate-5-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_191424" ], "products": [ "species_29370", "species_191296" ], "modifiers": [ [ "species_10736109", "catalyst" ] ], "additional_components": [ "Q09780", "SPAC13G6.11c" ] }, "reaction_10736122": { "compartment": "compartment_70101", "id": "reaction_10736122", "reactome": "R-SPO-191382", "name": "Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191362" ], "products": [ "species_191324" ], "modifiers": [ [ "species_10736119", "catalyst" ] ], "additional_components": [ "Q10132", "SPBC106.15", "species_29926" ] }, "reaction_10736299": { "compartment": "compartment_70101", "id": "reaction_10736299", "reactome": "R-SPO-194641", "name": "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_194644", "species_29368" ], "products": [ "species_29366", "species_194735", "species_29356" ], "modifiers": [ [ "species_10736296", "catalyst" ] ], "additional_components": [ "SPAC630.08c" ] }, "reaction_10736064": { "compartment": "compartment_70101", "id": "reaction_10736064", "reactome": "R-SPO-191299", "name": "Squalene is oxidized to its epoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_191269", "species_29368" ], "products": [ "species_29366", "species_191309", "species_29356" ], "modifiers": [ [ "species_10736061", "catalyst" ] ], "additional_components": [ "Q9C1W3", "SPBC713.12", "species_113596" ] }, "reaction_10736132": { "compartment": "compartment_70101", "id": "reaction_10736132", "reactome": "R-SPO-191402", "name": "Reduction of presqualene diphosphate to form squalene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_191265", "species_29364" ], "products": [ "species_29366", "species_191269", "species_111294" ], "modifiers": [ [ "species_10736129", "catalyst" ] ], "additional_components": [ "P36596", "SPBC646.05c", "species_29926" ] }, "reaction_10735725": { "compartment": "compartment_7660", "id": "reaction_10735725", "reactome": "R-SPO-176318", "name": "Loading of claspin onto DNA during replication origin firing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735715", "species_10728877" ], "products": [ "species_10735717" ], "modifiers": [], "additional_components": [ "SPAC694.06c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "O59836", "SPCC550.13", "P30666", "SPCC1682.02c", "P49731", "SPBC211.04c", "O74796", "SPBC2A9.12", "O42709", "SPBC1347.10", "O43114", "SPBC646.14c", "P50582", "SPBC776.12c", "O74113", "SPAC17D4.02", "P41411", "SPBC14C8.07c", "P04551", "SPBC11B10.09", "P40377", "SPBC4.04c", "P54789", "SPBC29A10.15", "O75001", "SPBC25D12.03c", "Q9P7T4", "SPAC694.06c" ] }, "reaction_10735710": { "compartment": "compartment_7660", "id": "reaction_10735710", "reactome": "R-SPO-176264", "name": "Recruitment of the Rad9-Hus1-Rad1 complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735705", "species_10735676" ], "products": [ "species_10735707" ], "modifiers": [ [ "species_10735676", "catalyst" ] ], "additional_components": [ "P26306", "SPAC664.07c", "P78955", "SPAC20G4.04c", "P22193", "SPAC1952.07", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13", "P26306", "SPAC664.07c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "P78955", "SPAC20G4.04c", "O14003", "SPAC27E2.10c", "P22193", "SPAC1952.07", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13" ] }, "reaction_10732950": { "compartment": "compartment_7660", "id": "reaction_10732950", "reactome": "R-SPO-75010", "name": "Phosphorylation of Cdc25C at Ser 216 by Chk1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732945", "species_29358" ], "products": [ "species_113582", "species_10732948" ], "modifiers": [ [ "species_10729605", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "O13945", "SPAC23H4.02", "O74536", "SPCC74.03c" ] }, "reaction_10735678": { "compartment": "compartment_7660", "id": "reaction_10735678", "reactome": "R-SPO-176101", "name": "Recruitment of Rad17-RFC complex to DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735674", "species_10735672" ], "products": [ "species_10735676" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "P50531", "SPAC14C4.13", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "P50531", "SPAC14C4.13" ] }, "reaction_10735686": { "compartment": "compartment_7660", "id": "reaction_10735686", "reactome": "R-SPO-176175", "name": "Stalling of DNA replication fork and RPA binding", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729504", "species_176104" ], "products": [ "species_10735674" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c" ] }, "reaction_10739846": { "compartment": "compartment_70101", "id": "reaction_10739846", "reactome": "R-SPO-450400", "name": "ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_450597", "species_10739831", "species_10739842" ], "products": [ "species_10739844" ], "modifiers": [], "additional_components": [ "SPAC2F3.06c", "SPBC1718.07c", "P47979", "SPBC1718.07c", "O14089", "SPAC2F3.06c" ] }, "reaction_10744332": { "compartment": "compartment_70101", "id": "reaction_10744332", "reactome": "R-SPO-3371591", "name": "Trimerization of cytosolic HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744185" ], "products": [ "species_10744288" ], "modifiers": [ [ "species_10734704", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10" ] }, "reaction_10744290": { "compartment": "compartment_70101", "id": "reaction_10744290", "reactome": "R-SPO-3371527", "name": "HSF1 trimer translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744288" ], "products": [ "species_10744252" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10745134": { "compartment": "compartment_7660", "id": "reaction_10745134", "reactome": "R-SPO-5082409", "name": "Dissociation of HSF1:HSP90 complex in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745132" ], "products": [ "species_10745124", "species_10745130", "species_10745102" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "P41887", "SPAC926.04c", "Q02953", "SPAC2E12.02", "SPAC9E9.13", "P41887", "SPAC926.04c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10745615": { "compartment": "compartment_70101", "id": "reaction_10745615", "reactome": "R-SPO-5324632", "name": "Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745610", "species_5324631" ], "products": [ "species_10745612", "species_10744185", "species_10744270", "species_10737648" ], "modifiers": [ [ "species_10745610", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "Q9P3A7", "SPAC1565.08", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "P56523", "SPBC800.03", "Q9P3A7", "SPAC1565.08", "P56523", "SPBC800.03", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "SPAC9E9.13", "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "Q9P3A7", "SPAC1565.08", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "P56523", "SPBC800.03" ] }, "reaction_10745104": { "compartment": "compartment_7660", "id": "reaction_10745104", "reactome": "R-SPO-5082391", "name": "Trimerization of HSF1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745102" ], "products": [ "species_10744252" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02" ] }, "reaction_10744324": { "compartment": "compartment_70101", "id": "reaction_10744324", "reactome": "R-SPO-3371586", "name": "Dissociation of cytosolic HSF1:HSP90 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744322" ], "products": [ "species_10744185", "species_10744270", "species_10737648" ], "modifiers": [], "additional_components": [ "O14283", "SPAC8C9.14", "Q11118", "SPAC9E9.13", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P41887", "SPAC926.04c", "SPAC9E9.13" ] }, "reaction_10730060": { "compartment": "compartment_5460", "id": "reaction_10730060", "reactome": "R-SPO-70724", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_508190" ], "products": [ "species_113552", "species_508181" ], "modifiers": [ [ "species_10730057", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "O14370", "SPBC428.02c" ] }, "reaction_10730068": { "compartment": "compartment_5460", "id": "reaction_10730068", "reactome": "R-SPO-70881", "name": "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71847", "species_113521" ], "products": [ "species_29374", "species_573404" ], "modifiers": [ [ "species_10730065", "catalyst" ] ], "additional_components": [ "SPBC2D10.09" ] }, "reaction_10730052": { "compartment": "compartment_70101", "id": "reaction_10730052", "reactome": "R-SPO-70723", "name": "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_508182", "species_29406" ], "products": [ "species_29404", "species_508187" ], "modifiers": [ [ "species_10730049", "catalyst" ] ], "additional_components": [ "CHEBI:58045", "CHEBI:57427", "CHEBI:57762", "CHEBI:28654", "CHEBI:16530", "CHEBI:17865", "O14370", "SPBC428.02c" ] }, "reaction_10756331": { "compartment": "compartment_5460", "id": "reaction_10756331", "reactome": "R-SPO-8952873", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113600", "species_77343", "species_113529" ], "products": [ "species_113563", "species_77308" ], "modifiers": [ [ "species_10756328", "catalyst" ] ], "additional_components": [ "Q10488", "SPAC26F1.04c" ] }, "reaction_10744576": { "compartment": "compartment_7660", "id": "reaction_10744576", "reactome": "R-SPO-3782655", "name": "HDAC10 deacetylates histone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10744514" ], "products": [ "species_5566518", "species_10744522" ], "modifiers": [ [ "species_10744573", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "SPBC800.03" ] }, "reaction_10744558": { "compartment": "compartment_7660", "id": "reaction_10744558", "reactome": "R-SPO-3769447", "name": "HDAC1:2-containing complex deacetylate histones", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10744514" ], "products": [ "species_5566518", "species_10744522" ], "modifiers": [ [ "species_10744553", "catalyst" ], [ "species_10744556", "inhibitor" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "O94405", "SPCC126.13c", "O74365", "SPBC30B4.04c", "LigandDisplayForward?ligandId=7489", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "LigandDisplayForward?ligandId=6852", "O94405", "SPCC126.13c", "LigandDisplayForward?ligandId=7496", "O74365", "SPBC30B4.04c" ] }, "reaction_10757824": { "compartment": "compartment_7660", "id": "reaction_10757824", "reactome": "R-SPO-9679787", "name": "HDAC1:2-containing complex binds HDAC2 Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744553", "species_9679795" ], "products": [ "species_10744556" ], "modifiers": [], "additional_components": [ "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "O94405", "SPCC126.13c", "O74365", "SPBC30B4.04c", "LigandDisplayForward?ligandId=7489", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "LigandDisplayForward?ligandId=6852", "LigandDisplayForward?ligandId=7496", "LigandDisplayForward?ligandId=7489", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "O59702", "SPBC36.05c", "LigandDisplayForward?ligandId=7009", "LigandDisplayForward?ligandId=7006", "O94244", "SPCC1672.10", "Q9P7M1", "SPBC21C3.02c", "LigandDisplayForward?ligandId=6852", "O94405", "SPCC126.13c", "LigandDisplayForward?ligandId=7496", "O74365", "SPBC30B4.04c" ] }, "reaction_10746196": { "compartment": "compartment_70101", "id": "reaction_10746196", "reactome": "R-SPO-5623667", "name": "PDPK1 phosphorylates PKN1,2,3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746165", "species_113592" ], "products": [ "species_29370", "species_10746193", "species_10738584", "species_10733718" ], "modifiers": [ [ "species_10746165", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "species_179838", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_179838", "Q12701", "SPCC576.15c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "species_179838", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c" ] }, "reaction_10746163": { "compartment": "compartment_876", "id": "reaction_10746163", "reactome": "R-SPO-5623622", "name": "RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746159", "species_10738584" ], "products": [ "species_10746161" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "P36582", "SPAC17G8.14c" ] }, "reaction_10746167": { "compartment": "compartment_876", "id": "reaction_10746167", "reactome": "R-SPO-5623632", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733718", "species_10746161" ], "products": [ "species_10746165" ], "modifiers": [], "additional_components": [ "species_179838", "Q12701", "SPCC576.15c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "P36582", "SPAC17G8.14c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "species_179838", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q12701", "SPCC576.15c", "P36582", "SPAC17G8.14c" ] }, "reaction_10746791": { "compartment": "compartment_70101", "id": "reaction_10746791", "reactome": "R-SPO-5671749", "name": "p-T774-PKN1 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746786" ], "products": [ "species_29370", "species_10746175", "species_10732952" ], "modifiers": [ [ "species_10746786", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P06652", "SPAC24H6.05", "P36582", "SPAC17G8.14c", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "SPAC24H6.05", "P36583", "SPBC12D12.04c", "P06652", "SPAC24H6.05", "P36582", "SPAC17G8.14c" ] }, "reaction_10746788": { "compartment": "compartment_70101", "id": "reaction_10746788", "reactome": "R-SPO-5671737", "name": "p-T774-PKN1 binds CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746175", "species_10734625" ], "products": [ "species_10746786" ], "modifiers": [], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "SPAC24H6.05", "P36583", "SPBC12D12.04c", "P06652", "SPAC24H6.05", "P36582", "SPAC17G8.14c" ] }, "reaction_10756168": { "compartment": "compartment_70101", "id": "reaction_10756168", "reactome": "R-SPO-8951644", "name": "Release of mature NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749457" ], "products": [ "species_10749455", "species_10749446" ], "modifiers": [], "additional_components": [ "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c", "SPBC12D12.08c", "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c" ] }, "reaction_10756413": { "compartment": "compartment_70101", "id": "reaction_10756413", "reactome": "R-SPO-8955241", "name": "CAND1 binds cytosolic CRL E3 ubiquitin ligases", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749492", "species_10756409" ], "products": [ "species_10756411" ], "modifiers": [], "additional_components": [ "SPAC1565.07c", "Q9UTL5", "SPAC144.09c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9USX9", "SPBC1861.07", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "P10815", "SPBC582.03", "Q10311", "SPAC6C3.08", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "Q9UTL5", "SPAC144.09c", "Q9P3A8", "SPAC1565.07c", "Q09760", "SPAC24H6.03", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "Q09838", "SPAC4G8.13c", "P36630", "SPAPB2B4.03", "Q9USX9", "SPBC1861.07", "O94289", "SPBC887.04c", "O74531", "SPCC1827.08c", "P10815", "SPBC582.03", "Q10311", "SPAC6C3.08", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12" ] }, "reaction_10749462": { "compartment": "compartment_70101", "id": "reaction_10749462", "reactome": "R-SPO-5690808", "name": "UCHL3, SENP8 cleave NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749453", "species_29356" ], "products": [ "species_10749457", "species_10749459" ], "modifiers": [ [ "species_10749453", "catalyst" ] ], "additional_components": [ "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c", "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c", "SPBC12D12.08c", "O13612", "SPBC32H8.02c", "Q10171", "SPAC27F1.03c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756192": { "compartment": "compartment_70101", "id": "reaction_10756192", "reactome": "R-SPO-8951656", "name": "NEDD8-UBA3:NAE1 binds a second NEDD8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749455", "species_113592", "species_10756185" ], "products": [ "species_10756190", "species_111294", "species_76577" ], "modifiers": [], "additional_components": [ "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756321": { "compartment": "compartment_7660", "id": "reaction_10756321", "reactome": "R-SPO-8952638", "name": "AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756294" ], "products": [ "species_10756296", "species_10756318" ], "modifiers": [ [ "species_10756294", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "Q8WZK4", "SPBC839.03c", "SPCC777.10c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O14399", "SPBC12D12.08c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "Q8WZK4", "SPBC839.03c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "Q8WZK4", "SPBC839.03c" ] }, "reaction_10756214": { "compartment": "compartment_70101", "id": "reaction_10756214", "reactome": "R-SPO-8951751", "name": "Doubly neddylated UBA3:NAE1 binds AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756195", "species_10756190" ], "products": [ "species_10756197" ], "modifiers": [], "additional_components": [ "SPCC777.10c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756208": { "compartment": "compartment_70101", "id": "reaction_10756208", "reactome": "R-SPO-8951661", "name": "Transfer of NEDD8 to AcM-UBE2M", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756197" ], "products": [ "species_10756205", "species_10756185" ], "modifiers": [ [ "species_10756197", "catalyst" ] ], "additional_components": [ "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O74549", "SPCC777.10c", "O14399", "SPBC12D12.08c" ] }, "reaction_10756250": { "compartment": "compartment_70101", "id": "reaction_10756250", "reactome": "R-SPO-8952618", "name": "AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756235" ], "products": [ "species_10756195", "species_10756247" ], "modifiers": [ [ "species_10756235", "catalyst" ] ], "additional_components": [ "O94289", "SPBC887.04c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O74531", "SPCC1827.08c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "O74549", "SPCC777.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O14399", "SPBC12D12.08c", "Q8WZK4", "SPBC839.03c", "SPCC777.10c", "O94289", "SPBC887.04c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O74531", "SPCC1827.08c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O14399", "SPBC12D12.08c", "Q8WZK4", "SPBC839.03c", "O94289", "SPBC887.04c", "Q9Y709", "SPBC409.05", "O13959", "SPAC23H4.18c", "O74531", "SPCC1827.08c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "O74549", "SPCC777.10c", "Q09855", "SPAC29E6.01", "O13790", "SPAC17G6.12", "O14399", "SPBC12D12.08c", "Q8WZK4", "SPBC839.03c" ] }, "reaction_10756419": { "compartment": "compartment_7660", "id": "reaction_10756419", "reactome": "R-SPO-8955245", "name": "CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756415", "species_10756280" ], "products": [ "species_10756417" ], "modifiers": [], "additional_components": [ "SPAC1565.07c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08", "O13807", "SPAC17H9.10c", "Q9P3A8", "SPAC1565.07c", "O13959", "SPAC23H4.18c", "O43017", "SPBC354.03", "O14021", "SPAC29A4.18", "O14122", "SPAC3A11.08", "O74340", "SPBC1A4.07c", "O42858", "SPAC23H3.05c", "Q9Y825", "SPAC25H1.06", "O94527", "SPBC609.03", "Q09873", "SPAC12G12.10", "O94244", "SPCC1672.10", "Q10990", "SPAC17H9.19c", "Q9USR0", "SPBC577.09", "O74763", "SPBC17D11.08" ] }, "reaction_10756188": { "compartment": "compartment_70101", "id": "reaction_10756188", "reactome": "R-SPO-8951648", "name": "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749455", "species_10756175", "species_113592" ], "products": [ "species_111294", "species_10756185", "species_76577" ], "modifiers": [ [ "species_10756175", "catalyst" ] ], "additional_components": [ "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c", "O14399", "SPBC12D12.08c", "Q9UT93", "SPAC323.06c", "Q09765", "SPAC24H6.12c" ] }, "reaction_10754241": { "compartment": "compartment_70101", "id": "reaction_10754241", "reactome": "R-SPO-8853514", "name": "UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754239" ], "products": [ "species_10729083", "species_10732101" ], "modifiers": [ [ "species_10754226", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09879", "SPCC188.08c", "Q10171", "SPAC27F1.03c" ] }, "reaction_10754194": { "compartment": "compartment_70101", "id": "reaction_10754194", "reactome": "R-SPO-8852134", "name": "UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741355", "species_113592", "species_10729165" ], "products": [ "species_10754094", "species_111294" ], "modifiers": [ [ "species_10741355", "catalyst" ] ], "additional_components": [ "SPBC1604.21c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC1604.21c" ] }, "reaction_10754183": { "compartment": "compartment_7660", "id": "reaction_10754183", "reactome": "R-SPO-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754148", "species_10754162" ], "products": [ "species_10754181", "species_10753992" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P23566", "SPAC18B11.07c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH07", "SPAC1805.12c", "P23566", "SPAC18B11.07c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10753994": { "compartment": "compartment_7660", "id": "reaction_10753994", "reactome": "R-SPO-8852128", "name": "UBA1 adenylates ubiquitin in the nucleoplasm", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10753862", "species_10729044" ], "products": [ "species_113541", "species_10753992" ], "modifiers": [], "additional_components": [ "SPBC1604.21c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754144": { "compartment": "compartment_70101", "id": "reaction_10754144", "reactome": "R-SPO-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753996", "species_10754092" ], "products": [ "species_10754094", "species_10754142" ], "modifiers": [], "additional_components": [ "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "Q9Y818", "SPBC1105.09", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74810", "SPBC2D10.20", "Q9P7R4", "SPBC211.07c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9Y818", "SPBC1105.09", "P0C8R3", "SPAC589.10c", "O00103", "SPCC1259.15c", "Q9UTN8", "SPAC1250.03", "P46595", "SPBC119.02", "O00102", "SPBP16F5.04", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754254": { "compartment": "compartment_70101", "id": "reaction_10754254", "reactome": "R-SPO-8853515", "name": "OTULIN,USP5 cleaves UBC yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754251" ], "products": [ "species_10729083", "species_10729113", "species_10729093", "species_10729103", "species_10729163", "species_10729153", "species_10729143", "species_10729133", "species_10729123" ], "modifiers": [ [ "species_10748788", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC6B1.06c" ] }, "reaction_10754191": { "compartment": "compartment_70101", "id": "reaction_10754191", "reactome": "R-SPO-8852133", "name": "UBA1 conjugates ubiquitin to UBA1 in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754094" ], "products": [ "species_10753998", "species_76577" ], "modifiers": [ [ "species_10754094", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754188": { "compartment": "compartment_70101", "id": "reaction_10754188", "reactome": "R-SPO-8852132", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10753998", "species_10729165" ], "products": [ "species_10754092", "species_111294" ], "modifiers": [ [ "species_10753998", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754196": { "compartment": "compartment_7660", "id": "reaction_10754196", "reactome": "R-SPO-8852136", "name": "UBA1 conjugates ubiquitin to UBA1 in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10753992" ], "products": [ "species_10754146", "species_164121" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754185": { "compartment": "compartment_7660", "id": "reaction_10754185", "reactome": "R-SPO-8852131", "name": "Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754146", "species_29358", "species_10729044" ], "products": [ "species_10754148", "species_113541" ], "modifiers": [], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O94609", "SPBC1604.21c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10754266": { "compartment": "compartment_70101", "id": "reaction_10754266", "reactome": "R-SPO-8853529", "name": "OTULIN,USP5 cleaves UBB yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10754264" ], "products": [ "species_10729083", "species_10729093", "species_10729103" ], "modifiers": [ [ "species_10748788", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC6B1.06c" ] }, "reaction_10754229": { "compartment": "compartment_70101", "id": "reaction_10754229", "reactome": "R-SPO-8853503", "name": "UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729083" ], "products": [ "species_10729083", "species_10731576" ], "modifiers": [ [ "species_10754226", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09879", "SPCC188.08c", "Q10171", "SPAC27F1.03c" ] }, "reaction_10732286": { "compartment": "compartment_70101", "id": "reaction_10732286", "reactome": "R-SPO-73577", "name": "CAD hexamer transforms L-Gln to CAP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_113592", "species_111627", "species_29356" ], "products": [ "species_70106", "species_29370", "species_29404", "species_29372", "species_111647" ], "modifiers": [ [ "species_10732277", "catalyst" ] ], "additional_components": [ "O94313", "SPBC215.08c", "Q09794", "SPAC22G7.06c" ] }, "reaction_10732266": { "compartment": "compartment_70101", "id": "reaction_10732266", "reactome": "R-SPO-73569", "name": "DHODH:FMN oxidises (S)-DHO to orotate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73663", "species_76630" ], "products": [ "species_76633", "species_76632" ], "modifiers": [ [ "species_10732263", "catalyst" ] ], "additional_components": [ "species_73524", "P32747", "SPAC57A10.12c" ] }, "reaction_10732280": { "compartment": "compartment_70101", "id": "reaction_10732280", "reactome": "R-SPO-73571", "name": "CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_111628" ], "products": [ "species_29356", "species_76630" ], "modifiers": [ [ "species_10732277", "catalyst" ] ], "additional_components": [ "O94313", "SPBC215.08c", "Q09794", "SPAC22G7.06c" ] }, "reaction_10732283": { "compartment": "compartment_70101", "id": "reaction_10732283", "reactome": "R-SPO-73573", "name": "CAD hexamer transforms CAP to N-carb-L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29448", "species_111647" ], "products": [ "species_70106", "species_29372", "species_111628" ], "modifiers": [ [ "species_10732277", "catalyst" ] ], "additional_components": [ "O94313", "SPBC215.08c", "Q09794", "SPAC22G7.06c" ] }, "reaction_10746504": { "compartment": "compartment_7660", "id": "reaction_10746504", "reactome": "R-SPO-5653780", "name": "USP43 binds ISG:K164,ISG:K168-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746500", "species_10746496" ], "products": [ "species_10746502" ], "modifiers": [], "additional_components": [ "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "O60079", "SPCC1494.05c", "Q9USM5", "SPCC16A11.12c", "O60079", "SPCC1494.05c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "Q9USM5", "SPCC16A11.12c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c" ] }, "reaction_10746510": { "compartment": "compartment_7660", "id": "reaction_10746510", "reactome": "R-SPO-5653838", "name": "POLD,POLE binds deISGylated PCNA after TLS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746506", "species_10734037" ], "products": [ "species_10746508" ], "modifiers": [], "additional_components": [ "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "C6Y4D0", "SPCC16C4.22", "Q03392", "SPBC16D10.09" ] }, "reaction_10733936": { "compartment": "compartment_7660", "id": "reaction_10733936", "reactome": "R-SPO-110234", "name": "Cleavage of ethenocytosine by TDG glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733933" ], "products": [ "species_10733889", "species_110233" ], "modifiers": [ [ "species_10733933", "catalyst" ] ], "additional_components": [ "O59825", "SPCC965.05c", "O59825", "SPCC965.05c", "O59825", "SPCC965.05c" ] }, "reaction_10734052": { "compartment": "compartment_7660", "id": "reaction_10734052", "reactome": "R-SPO-110368", "name": "POLD,POLE-mediated DNA strand displacement synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10734049" ], "products": [ "species_10734045", "species_113541" ], "modifiers": [ [ "species_10734049", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "P39750", "SPAC3G6.06c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "P39750", "SPAC3G6.06c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "P39750", "SPAC3G6.06c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10733885": { "compartment": "compartment_7660", "id": "reaction_10733885", "reactome": "R-SPO-110217", "name": "Cleavage of 5-hydroxyluracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733882" ], "products": [ "species_10733875", "species_110216" ], "modifiers": [ [ "species_10733882", "catalyst" ] ], "additional_components": [ "O74834", "SPCC1183.06", "O74834", "SPCC1183.06", "O74834", "SPCC1183.06" ] }, "reaction_10733892": { "compartment": "compartment_7660", "id": "reaction_10733892", "reactome": "R-SPO-110218", "name": "Cleavage of uracil by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733887" ], "products": [ "species_10733889", "species_29554" ], "modifiers": [ [ "species_10733887", "catalyst" ] ], "additional_components": [ "O59825", "SPCC965.05c", "O59825", "SPCC965.05c", "O59825", "SPCC965.05c" ] }, "reaction_10733899": { "compartment": "compartment_7660", "id": "reaction_10733899", "reactome": "R-SPO-110219", "name": "Cleavage of thymine by TDG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733896" ], "products": [ "species_29692", "species_10733889" ], "modifiers": [ [ "species_10733896", "catalyst" ] ], "additional_components": [ "O59825", "SPCC965.05c", "O59825", "SPCC965.05c", "O59825", "SPCC965.05c" ] }, "reaction_10746388": { "compartment": "compartment_7660", "id": "reaction_10746388", "reactome": "R-SPO-5651805", "name": "LIG1 bound to APEX1 and PCNA ligates SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734058" ], "products": [ "species_10746385" ], "modifiers": [ [ "species_10734058", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01" ] }, "reaction_10733929": { "compartment": "compartment_7660", "id": "reaction_10733929", "reactome": "R-SPO-110229", "name": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733926" ], "products": [ "species_5637659", "species_10733905" ], "modifiers": [ [ "species_10733926", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10733908": { "compartment": "compartment_7660", "id": "reaction_10733908", "reactome": "R-SPO-110224", "name": "Cleavage of thymine glycol by NTHL1 glycosylase ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733903" ], "products": [ "species_110223", "species_10733905" ], "modifiers": [ [ "species_10733903", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10733915": { "compartment": "compartment_7660", "id": "reaction_10733915", "reactome": "R-SPO-110226", "name": "Cleavage of cytosine glycol by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733912" ], "products": [ "species_10733905", "species_110225" ], "modifiers": [ [ "species_10733912", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10733952": { "compartment": "compartment_7660", "id": "reaction_10733952", "reactome": "R-SPO-110246", "name": "Cleavage of adenine mispaired with 8-oxoguanine by MUTYH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733947" ], "products": [ "species_10733949", "species_5635947" ], "modifiers": [ [ "species_10733947", "catalyst" ] ], "additional_components": [ "Q10159", "SPAC26A3.02", "Q10159", "SPAC26A3.02", "Q10159", "SPAC26A3.02" ] }, "reaction_10733878": { "compartment": "compartment_7660", "id": "reaction_10733878", "reactome": "R-SPO-110215", "name": "Cleavage of uracil by UNG glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733871" ], "products": [ "species_29554", "species_10733875" ], "modifiers": [ [ "species_10733871", "catalyst" ] ], "additional_components": [ "O74834", "SPCC1183.06", "O74834", "SPCC1183.06", "O74834", "SPCC1183.06" ] }, "reaction_10733922": { "compartment": "compartment_7660", "id": "reaction_10733922", "reactome": "R-SPO-110227", "name": "Cleavage of dihydrouracil by NTHL1 glycosylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733919" ], "products": [ "species_30140", "species_10733905" ], "modifiers": [ [ "species_10733919", "catalyst" ] ], "additional_components": [ "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07", "Q09907", "SPAC30D11.07" ] }, "reaction_10734060": { "compartment": "compartment_7660", "id": "reaction_10734060", "reactome": "R-SPO-110371", "name": "LIG1 binds APEX1 and PCNA at SSB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729536", "species_10734056" ], "products": [ "species_10734058" ], "modifiers": [], "additional_components": [ "SPAC20G8.01", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P12000", "SPAC20G8.01" ] }, "reaction_10735879": { "compartment": "compartment_984", "id": "reaction_10735879", "reactome": "R-SPO-189053", "name": "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189108", "species_109276" ], "products": [ "species_70115", "species_191103", "species_188986" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10736054": { "compartment": "compartment_984", "id": "reaction_10736054", "reactome": "R-SPO-191116", "name": "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191103", "species_109276" ], "products": [ "species_70115", "species_188986" ], "modifiers": [ [ "species_10735886", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c" ] }, "reaction_10736052": { "compartment": "compartment_984", "id": "reaction_10736052", "reactome": "R-SPO-191108", "name": "maltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188986", "species_109276" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10735882": { "compartment": "compartment_984", "id": "reaction_10735882", "reactome": "R-SPO-189069", "name": "sucrose + H2O => glucose + fructose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_188980" ], "products": [ "species_70115", "species_189049" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10735889": { "compartment": "compartment_984", "id": "reaction_10735889", "reactome": "R-SPO-189102", "name": "maltose + H2O => 2 D-glucose (maltase-glucoamylase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_188986", "species_109276" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10735886", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c" ] }, "reaction_10746655": { "compartment": "compartment_984", "id": "reaction_10746655", "reactome": "R-SPO-5659861", "name": "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_5659875" ], "products": [ "species_70115" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10736050": { "compartment": "compartment_984", "id": "reaction_10736050", "reactome": "R-SPO-191101", "name": "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_191103", "species_109276" ], "products": [ "species_70115", "species_188986" ], "modifiers": [ [ "species_10735876", "catalyst" ] ], "additional_components": [ "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10728699": { "compartment": "compartment_7660", "id": "reaction_10728699", "reactome": "R-SPO-68611", "name": "Formation of ORC(1-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728693", "species_10728682" ], "products": [ "species_10728697" ], "modifiers": [], "additional_components": [ "P54789", "SPBC29A10.15", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15" ] }, "reaction_10758124": { "compartment": "compartment_7660", "id": "reaction_10758124", "reactome": "R-SPO-9757258", "name": "MCM2 binds MCM4:MCM6:MCM7 heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728828", "species_10728845" ], "products": [ "species_10728847" ], "modifiers": [], "additional_components": [ "SPBC4.04c", "P29458", "SPCC16A11.17", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "P29458", "SPCC16A11.17", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10758076": { "compartment": "compartment_7660", "id": "reaction_10758076", "reactome": "R-SPO-9749197", "name": "ORC1 binds to H4K20me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728689", "species_10758072" ], "products": [ "species_10758074" ], "modifiers": [], "additional_components": [ "SPBC29A10.15", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P54789", "SPBC29A10.15", "P04909", "SPCC622.08c" ] }, "reaction_10758120": { "compartment": "compartment_7660", "id": "reaction_10758120", "reactome": "R-SPO-9757256", "name": "MCM3 binds MCM5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728857", "species_10728852" ], "products": [ "species_10728859" ], "modifiers": [], "additional_components": [ "SPAC1B2.05", "SPCC1682.02c", "P41389", "SPAC1B2.05", "P30666", "SPCC1682.02c" ] }, "reaction_10728666": { "compartment": "compartment_7660", "id": "reaction_10728666", "reactome": "R-SPO-68595", "name": "ORC2 binds ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728657", "species_10728662" ], "products": [ "species_10728664" ], "modifiers": [], "additional_components": [ "SPBC685.09", "SPAC3H1.01c", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09" ] }, "reaction_10758078": { "compartment": "compartment_7660", "id": "reaction_10758078", "reactome": "R-SPO-9749253", "name": "Formation of MCM2-7 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728847", "species_10728859" ], "products": [ "species_10728861" ], "modifiers": [], "additional_components": [ "P29458", "SPCC16A11.17", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c", "P41389", "SPAC1B2.05", "P30666", "SPCC1682.02c", "P41389", "SPAC1B2.05", "P29458", "SPCC16A11.17", "P30666", "SPCC1682.02c", "P40377", "SPBC4.04c", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10758051": { "compartment": "compartment_70101", "id": "reaction_10758051", "reactome": "R-SPO-9734713", "name": "ORC6 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758033" ], "products": [ "species_10728705", "species_10758049" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12", "SPBC2A9.12", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c" ] }, "reaction_10758122": { "compartment": "compartment_7660", "id": "reaction_10758122", "reactome": "R-SPO-9757257", "name": "MCM4, MCM6 and MCM7 form a heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728843", "species_10728838", "species_10728833" ], "products": [ "species_10728845" ], "modifiers": [], "additional_components": [ "SPBC25D12.03c", "SPBC211.04c", "SPCC16A11.17", "P29458", "SPCC16A11.17", "P49731", "SPBC211.04c", "O75001", "SPBC25D12.03c" ] }, "reaction_10758029": { "compartment": "compartment_70101", "id": "reaction_10758029", "reactome": "R-SPO-9734670", "name": "ORC6 binds KPNA1 or KPNA6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758023", "species_10758025" ], "products": [ "species_10758027" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "SPBC2A9.12", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12" ] }, "reaction_10758055": { "compartment": "compartment_70101", "id": "reaction_10758055", "reactome": "R-SPO-9734730", "name": "ORC1 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758053" ], "products": [ "species_10728689" ], "modifiers": [], "additional_components": [ "SPBC29A10.15", "SPBC29A10.15" ] }, "reaction_10728675": { "compartment": "compartment_7660", "id": "reaction_10728675", "reactome": "R-SPO-68603", "name": "ORC5 binds ORC2:ORC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728671", "species_10728664" ], "products": [ "species_10728673" ], "modifiers": [], "additional_components": [ "SPBC646.14c", "Q10067", "SPAC3H1.01c", "Q09142", "SPBC685.09", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09" ] }, "reaction_10728684": { "compartment": "compartment_7660", "id": "reaction_10728684", "reactome": "R-SPO-68610", "name": "Formation of ORC(2-5) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728680", "species_10728673" ], "products": [ "species_10728682" ], "modifiers": [ [ "species_29358", "catalyst" ] ], "additional_components": [ "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09" ] }, "reaction_10728718": { "compartment": "compartment_7660", "id": "reaction_10728718", "reactome": "R-SPO-68688", "name": "CDC6 association with ORC(1-6) at replication origins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728714", "species_10728707" ], "products": [ "species_10728716" ], "modifiers": [], "additional_components": [ "SPBC14C8.07c", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15", "O74796", "SPBC2A9.12", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P41411", "SPBC14C8.07c", "P54789", "SPBC29A10.15", "O74796", "SPBC2A9.12" ] }, "reaction_10758035": { "compartment": "compartment_70101", "id": "reaction_10758035", "reactome": "R-SPO-9734687", "name": "ORC6 is phosphorylated on T195", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758027", "species_113592" ], "products": [ "species_29370", "species_10758033" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O13864", "SPAC1B1.03c", "O74796", "SPBC2A9.12" ] }, "reaction_10728709": { "compartment": "compartment_7660", "id": "reaction_10728709", "reactome": "R-SPO-68615", "name": "Formation of ORC(1-6) complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10728705", "species_10728697" ], "products": [ "species_10728707" ], "modifiers": [], "additional_components": [ "SPBC2A9.12", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15", "Q9Y794", "SPBP23A10.13", "Q10067", "SPAC3H1.01c", "O43114", "SPBC646.14c", "Q09142", "SPBC685.09", "P54789", "SPBC29A10.15", "O74796", "SPBC2A9.12" ] }, "reaction_10747495": { "compartment": "compartment_7660", "id": "reaction_10747495", "reactome": "R-SPO-5683792", "name": "p-T68-CHEK2 autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747490" ], "products": [ "species_113582", "species_10729617" ], "modifiers": [ [ "species_10747490", "catalyst" ] ], "additional_components": [ "Q10292", "SPAC14C4.03", "SPAC14C4.03", "Q10292", "SPAC14C4.03" ] }, "reaction_10747492": { "compartment": "compartment_7660", "id": "reaction_10747492", "reactome": "R-SPO-5683774", "name": "p-T68-CHEK2 dimerizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747488" ], "products": [ "species_10747490" ], "modifiers": [], "additional_components": [ "SPAC14C4.03", "Q10292", "SPAC14C4.03" ] }, "reaction_10734987": { "compartment": "compartment_7660", "id": "reaction_10734987", "reactome": "R-SPO-163748", "name": "Transcriptional activation of GP-acyl transferase gene by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10733361" ], "modifiers": [], "additional_components": [ "SPAC1851.02" ] }, "reaction_10734985": { "compartment": "compartment_7660", "id": "reaction_10734985", "reactome": "R-SPO-163743", "name": "Transcriptional activation of Acetyl-CoA carboxylase by ChREBP:MLX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [], "products": [ "species_10734983" ], "modifiers": [], "additional_components": [ "SPAC56E4.04c" ] }, "reaction_10734565": { "compartment": "compartment_70101", "id": "reaction_10734565", "reactome": "R-SPO-114684", "name": "Phosphorylation of Syntaxin-4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734560" ], "products": [ "species_29370", "species_10734563" ], "modifiers": [ [ "species_10734542", "catalyst" ] ], "additional_components": [ "SPCC825.03c", "SPCC825.03c", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10734555": { "compartment": "compartment_70101", "id": "reaction_10734555", "reactome": "R-SPO-114683", "name": "Phosphorylation of Platelet Sec-1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734549" ], "products": [ "species_29370", "species_10734552" ], "modifiers": [ [ "species_10734542", "catalyst" ] ], "additional_components": [ "SPCC584.05", "SPCC584.05", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10735552": { "compartment": "compartment_70101", "id": "reaction_10735552", "reactome": "R-SPO-174389", "name": "PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174370", "species_113592" ], "products": [ "species_158471", "species_29370" ], "modifiers": [ [ "species_10735547", "catalyst" ] ], "additional_components": [ "SPAC1782.11" ] }, "reaction_10735571": { "compartment": "compartment_70101", "id": "reaction_10735571", "reactome": "R-SPO-174392", "name": "PAPSS1,2 transfer SO4(2-) group to ATP to form APS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174375", "species_113592" ], "products": [ "species_174370", "species_111294" ], "modifiers": [ [ "species_10735547", "catalyst" ] ], "additional_components": [ "SPAC1782.11" ] }, "reaction_10743381": { "compartment": "compartment_70101", "id": "reaction_10743381", "reactome": "R-SPO-2529015", "name": "Dephosphorylation of CK2-modified condensin I", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10743369" ], "products": [ "species_10743379", "species_29372" ], "modifiers": [ [ "species_2529006", "catalyst" ] ], "additional_components": [ "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13", "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13" ] }, "reaction_10743406": { "compartment": "compartment_70101", "id": "reaction_10743406", "reactome": "R-SPO-2529020", "name": "CK2 phosphorylates condensin I subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743379", "species_113592" ], "products": [ "species_29370", "species_10743369" ], "modifiers": [ [ "species_10743403", "catalyst" ] ], "additional_components": [ "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13", "P41003", "SPBP4H10.06c", "P41004", "SPBC146.03c", "Q9Y7R3", "SPCC306.03c", "Q10429", "SPCC188.03", "O94679", "SPBC776.13", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11" ] }, "reaction_10733244": { "compartment": "compartment_7660", "id": "reaction_10733244", "reactome": "R-SPO-75172", "name": "Formation of RAD50:MRE11 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733240", "species_10733235" ], "products": [ "species_10733242" ], "modifiers": [], "additional_components": [ "SPAC13C5.07", "SPAC1556.01c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c" ] }, "reaction_10749600": { "compartment": "compartment_7660", "id": "reaction_10749600", "reactome": "R-SPO-5693540", "name": "MRN activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747252", "species_29358" ], "products": [ "species_10737781", "species_113582", "species_10749597" ], "modifiers": [ [ "species_10747252", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "SPCC23B6.03c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747255": { "compartment": "compartment_7660", "id": "reaction_10747255", "reactome": "R-SPO-5682044", "name": "KAT5 acetylates ATM at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747250", "species_113560" ], "products": [ "species_2485002", "species_10747252" ], "modifiers": [ [ "species_10747250", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747567": { "compartment": "compartment_7660", "id": "reaction_10747567", "reactome": "R-SPO-5684006", "name": "KPNA2 translocates NBN to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747559" ], "products": [ "species_10747565", "species_10733249" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O43070", "SPBC6B1.09c", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "SPBC6B1.09c" ] }, "reaction_10733253": { "compartment": "compartment_7660", "id": "reaction_10733253", "reactome": "R-SPO-75174", "name": "Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733242", "species_10733249" ], "products": [ "species_10733251" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10747569": { "compartment": "compartment_70101", "id": "reaction_10747569", "reactome": "R-SPO-5684008", "name": "NBN binds KPNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747555", "species_10747557" ], "products": [ "species_10747559" ], "modifiers": [], "additional_components": [ "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "SPBC6B1.09c", "O14063", "SPCC962.03c", "O94374", "SPBC1604.08c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744580": { "compartment": "compartment_7660", "id": "reaction_10744580", "reactome": "R-SPO-3785768", "name": "MRN complex binds DNA double strand breaks", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733251", "species_75165" ], "products": [ "species_10744578" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10749630": { "compartment": "compartment_7660", "id": "reaction_10749630", "reactome": "R-SPO-5693612", "name": "MRN complex bound to DNA ends recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747231", "species_10744578" ], "products": [ "species_10747250" ], "modifiers": [], "additional_components": [ "Q10325", "SPAC17G8.13c", "O74630", "SPCC23B6.03c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10730078": { "compartment": "compartment_5460", "id": "reaction_10730078", "reactome": "R-SPO-70938", "name": "lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113600", "species_29444", "species_113529" ], "products": [ "species_113563", "species_113521", "species_30176" ], "modifiers": [ [ "species_10730075", "catalyst" ] ], "additional_components": [ "O59711", "SPBC3B8.03" ] }, "reaction_10730211": { "compartment": "compartment_5460", "id": "reaction_10730211", "reactome": "R-SPO-71037", "name": "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113526", "species_70951" ], "products": [ "species_70955", "species_29376", "species_29362" ], "modifiers": [ [ "species_10730208", "catalyst" ] ], "additional_components": [ "O94681", "SPBC776.15c", "species_29480", "O00087", "SPAC1002.09c", "CHEBI:17460", "O74378", "SPBC3H7.03c", "species_113596" ] }, "reaction_10730081": { "compartment": "compartment_5460", "id": "reaction_10730081", "reactome": "R-SPO-70940", "name": "saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_30176" ], "products": [ "species_113556", "species_113552", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730075", "catalyst" ] ], "additional_components": [ "O59711", "SPBC3B8.03" ] }, "reaction_10750324": { "compartment": "compartment_17951", "id": "reaction_10750324", "reactome": "R-SPO-6783880", "name": "PIPOX oxidises PPCA to P6C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693325", "species_113535" ], "products": [ "species_6783877", "species_113575" ], "modifiers": [ [ "species_10750321", "catalyst" ] ], "additional_components": [ "SPBC354.15" ] }, "reaction_10753848": { "compartment": "compartment_984", "id": "reaction_10753848", "reactome": "R-SPO-8851396", "name": "NTPDase6 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851462", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851461" ], "modifiers": [ [ "species_10753845", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58280", "species_110094", "species_110096", "species_109395", "species_29602", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753831": { "compartment": "compartment_17963", "id": "reaction_10753831", "reactome": "R-SPO-8851225", "name": "NTPDase4 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851224", "species_2022884" ], "products": [ "species_8851227", "species_425969", "species_8851226" ], "modifiers": [ [ "species_10753828", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "species_110094", "species_110096", "species_109366", "species_109395", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c" ] }, "reaction_10753786": { "compartment": "compartment_876", "id": "reaction_10753786", "reactome": "R-SPO-8850854", "name": "NTPDase1 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753780", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753824": { "compartment": "compartment_984", "id": "reaction_10753824", "reactome": "R-SPO-8851129", "name": "NTPDase3 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8870906", "species_109276" ], "products": [ "species_8870962", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753818", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753834": { "compartment": "compartment_17963", "id": "reaction_10753834", "reactome": "R-SPO-8851234", "name": "NTPDase4 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851233", "species_2022884" ], "products": [ "species_425969", "species_8851224", "species_8851226" ], "modifiers": [ [ "species_10753828", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "species_110094", "species_110096", "species_74016", "Q9USP2", "SPCC11E10.05c" ] }, "reaction_10753821": { "compartment": "compartment_984", "id": "reaction_10753821", "reactome": "R-SPO-8851110", "name": "NTPDase3 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753818", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753855": { "compartment": "compartment_528865", "id": "reaction_10753855", "reactome": "R-SPO-8851494", "name": "NTPDase7 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8851509", "species_8851517" ], "products": [ "species_8851518", "species_8851513", "species_5228597" ], "modifiers": [ [ "species_10753852", "catalyst" ] ], "additional_components": [ "species_29494", "species_29438", "species_110614", "species_29420", "species_110096", "species_110094", "species_74016", "Q9USP2", "SPCC11E10.05c" ] }, "reaction_10753783": { "compartment": "compartment_984", "id": "reaction_10753783", "reactome": "R-SPO-8850846", "name": "NTPDase1 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8870907" ], "products": [ "species_8870906", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753780", "catalyst" ] ], "additional_components": [ "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753857": { "compartment": "compartment_984", "id": "reaction_10753857", "reactome": "R-SPO-8851538", "name": "NTPDase8 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726184", "species_109276" ], "products": [ "species_9726189", "species_109277", "species_351626" ], "modifiers": [ [ "species_10753811", "catalyst" ] ], "additional_components": [ "species_29494", "species_30187", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753841": { "compartment": "compartment_984", "id": "reaction_10753841", "reactome": "R-SPO-8851356", "name": "NTPDase5 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8936165", "species_109276" ], "products": [ "species_109277", "species_351626", "species_8851369" ], "modifiers": [ [ "species_10753838", "catalyst" ] ], "additional_components": [ "species_29420", "species_29370", "species_110094", "species_110096", "species_109395", "species_76577", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753814": { "compartment": "compartment_984", "id": "reaction_10753814", "reactome": "R-SPO-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_8936166" ], "products": [ "species_109277", "species_351626", "species_8851092" ], "modifiers": [ [ "species_10753811", "catalyst" ] ], "additional_components": [ "species_29494", "species_113592", "species_2509836", "species_29438", "species_110614", "species_29420", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10753860": { "compartment": "compartment_984", "id": "reaction_10753860", "reactome": "R-SPO-8851550", "name": "NTPDase8 hydrolyzes nucleoside diphosphates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9726189", "species_109276" ], "products": [ "species_109277", "species_351626", "species_9726186" ], "modifiers": [ [ "species_10753811", "catalyst" ] ], "additional_components": [ "species_29420", "CHEBI:58369", "CHEBI:58280", "species_29370", "species_110096", "species_110094", "species_109366", "species_109395", "species_29602", "species_76577", "species_418075", "species_29626", "species_74016", "Q9USP2", "SPCC11E10.05c", "species_29926" ] }, "reaction_10746363": { "compartment": "compartment_13949", "id": "reaction_10746363", "reactome": "R-SPO-5638014", "name": "RAB11A:GTP-containing Golgi vesicles recruit RAB3IP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746359", "species_10746347" ], "products": [ "species_10746361" ], "modifiers": [], "additional_components": [ "O13930", "SPAC23C4.10", "C6Y4C9", "SPCC1183.12", "P17610", "SPAC18G6.03", "species_29438", "P17610", "SPAC18G6.03", "O13930", "SPAC23C4.10", "C6Y4C9", "SPCC1183.12", "species_29438" ] }, "reaction_10756951": { "compartment": "compartment_70101", "id": "reaction_10756951", "reactome": "R-SPO-9018814", "name": "RHOT1 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756946", "species_29356" ], "products": [ "species_10756948", "species_29372" ], "modifiers": [ [ "species_10756946", "catalyst" ] ], "additional_components": [ "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "species_29420", "O59781", "SPCC320.04c", "species_29438" ] }, "reaction_10756961": { "compartment": "compartment_17906", "id": "reaction_10756961", "reactome": "R-SPO-9018815", "name": "RHOT1 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756957", "species_10756946" ], "products": [ "species_10756959" ], "modifiers": [], "additional_components": [ "O74805", "SPBC2D10.14c", "O94477", "SPCC1919.10c", "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "O74805", "SPBC2D10.14c", "species_29438", "O94477", "SPCC1919.10c" ] }, "reaction_10746671": { "compartment": "compartment_70101", "id": "reaction_10746671", "reactome": "R-SPO-5662471", "name": "SORD tetramer oxidizes xylitol to D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5660033", "species_29360" ], "products": [ "species_70106", "species_73473", "species_5661281" ], "modifiers": [ [ "species_10746446", "catalyst" ] ], "additional_components": [ "species_442320", "P36624", "SPBC1773.05c" ] }, "reaction_10746668": { "compartment": "compartment_70101", "id": "reaction_10746668", "reactome": "R-SPO-5662466", "name": "XYLB phosphorylates D-xylulose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5661281", "species_113592" ], "products": [ "species_29370", "species_29790" ], "modifiers": [ [ "species_10746665", "catalyst" ] ], "additional_components": [ "SPCPJ732.02c" ] }, "reaction_10746139": { "compartment": "compartment_70101", "id": "reaction_10746139", "reactome": "R-SPO-5623508", "name": "GBF1 stimulates nucleotide exchange on ARF4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10746137" ], "products": [ "species_10746135", "species_29420" ], "modifiers": [ [ "species_10737885", "catalyst" ] ], "additional_components": [ "species_29420", "P36579", "SPBC4F6.18c", "P36579", "SPBC4F6.18c", "species_29438", "O13817", "SPAC19A8.01c", "O13690", "SPBC211.03c", "Q10491", "SPAC26F1.01", "Q9P7R8", "SPBC211.03c" ] }, "reaction_10745780": { "compartment": "compartment_7660", "id": "reaction_10745780", "reactome": "R-SPO-5358513", "name": "MSH2:MSH3 binds insertion/deletion loop of 2 bases or more", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358527", "species_10745776" ], "products": [ "species_10745778" ], "modifiers": [], "additional_components": [ "P26359", "SPAC8F11.03", "O74773", "SPBC19G7.01c", "species_29370", "P26359", "SPAC8F11.03", "O74773", "SPBC19G7.01c", "species_29370" ] }, "reaction_10750285": { "compartment": "compartment_7660", "id": "reaction_10750285", "reactome": "R-SPO-6782227", "name": "Ligation of newly synthesized repair patch to incised DNA in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750271" ], "products": [ "species_10749293", "species_10750283" ], "modifiers": [ [ "species_10729536", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "P49373", "SPAC20H4.03c", "Q09879", "SPCC188.08c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "SPAC20G8.01" ] }, "reaction_10746607": { "compartment": "compartment_7660", "id": "reaction_10746607", "reactome": "R-SPO-5655835", "name": "POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746599", "species_10746603", "species_10733995", "species_10733957" ], "products": [ "species_10746605" ], "modifiers": [], "additional_components": [ "O74944", "SPCC553.07c", "species_113527", "species_29926", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "SPBC1347.01c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "Q0E7J8", "SPBC12D12.09", "P0C8R3", "SPAC589.10c", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746433": { "compartment": "compartment_7660", "id": "reaction_10746433", "reactome": "R-SPO-5652009", "name": "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746426", "species_10729044" ], "products": [ "species_10746430", "species_10734037", "species_10746424" ], "modifiers": [ [ "species_10746426", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "Q10990", "SPAC17H9.19c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "Q10990", "SPAC17H9.19c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "Q10990", "SPAC17H9.19c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10745785": { "compartment": "compartment_7660", "id": "reaction_10745785", "reactome": "R-SPO-5358518", "name": "MLH1:PMS2 makes single strand incision near 1-2 base mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745767" ], "products": [ "species_10745782" ], "modifiers": [ [ "species_10745767", "catalyst" ] ], "additional_components": [ "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10749595": { "compartment": "compartment_7660", "id": "reaction_10749595", "reactome": "R-SPO-5693536", "name": "ATM phosphorylates MDC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10749592" ], "products": [ "species_113582", "species_10747437" ], "modifiers": [ [ "species_10749592", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10745797": { "compartment": "compartment_7660", "id": "reaction_10745797", "reactome": "R-SPO-5358592", "name": "DNA ligase I ligates single stranded nick in double stranded DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358610", "species_29358" ], "products": [ "species_109966", "species_164121", "species_113541" ], "modifiers": [ [ "species_10729536", "catalyst" ] ], "additional_components": [ "SPAC20G8.01" ] }, "reaction_10747479": { "compartment": "compartment_7660", "id": "reaction_10747479", "reactome": "R-SPO-5683405", "name": "PPP5C dephosphorylates TP53BP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747469" ], "products": [ "species_113550", "species_10747471" ], "modifiers": [ [ "species_10747476", "catalyst" ] ], "additional_components": [ "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P87074", "SPBC342.05", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c", "SPBC3F6.01c" ] }, "reaction_10750503": { "compartment": "compartment_7660", "id": "reaction_10750503", "reactome": "R-SPO-6790454", "name": "SUMOylation of XPC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749477", "species_10750487" ], "products": [ "species_10743639", "species_10750496" ], "modifiers": [ [ "species_10750500", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "Q9HDW3", "SPBC32F12.15", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "O13351", "SPBC365.06", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O94451", "SPAC1687.05" ] }, "reaction_10733974": { "compartment": "compartment_7660", "id": "reaction_10733974", "reactome": "R-SPO-110307", "name": "REV1 binds AP-dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733970", "species_10733957" ], "products": [ "species_10733972" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC1347.01c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746644": { "compartment": "compartment_7660", "id": "reaction_10746644", "reactome": "R-SPO-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10746635" ], "products": [ "species_10746641", "species_113541" ], "modifiers": [ [ "species_10746635", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749297": { "compartment": "compartment_7660", "id": "reaction_10749297", "reactome": "R-SPO-5690213", "name": "DNA polymerases delta, epsilon or kappa bind the GG-NER site", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749283", "species_10749285", "species_10749281", "species_10729448" ], "products": [ "species_10749295" ], "modifiers": [], "additional_components": [ "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "O94263", "SPBP8B7.14c", "P30261", "SPBC1734.02c", "O74944", "SPCC553.07c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "C6Y4D0", "SPCC16C4.22", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P36617", "SPCC970.01", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O59753", "SPBC649.03", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P28706", "SPBC3E7.08c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "O74366", "SPBC30B4.07c" ] }, "reaction_10745941": { "compartment": "compartment_7660", "id": "reaction_10745941", "reactome": "R-SPO-5444523", "name": "Formation of MSH1:PMS2 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745744", "species_10745749" ], "products": [ "species_10745751" ], "modifiers": [], "additional_components": [ "SPBC1703.04", "SPAC19G12.02c", "P54280", "SPAC19G12.02c", "Q9P7W6", "SPBC1703.04" ] }, "reaction_10747451": { "compartment": "compartment_7660", "id": "reaction_10747451", "reactome": "R-SPO-5682983", "name": "ATM phosphorylates WHSC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747446" ], "products": [ "species_113582", "species_10747439" ], "modifiers": [ [ "species_10747446", "catalyst" ] ], "additional_components": [ "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10747379": { "compartment": "compartment_7660", "id": "reaction_10747379", "reactome": "R-SPO-5682629", "name": "HERC2 facilitates UBE2N:UBE2V2 binding to RNF8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747364", "species_10747373" ], "products": [ "species_10747377" ], "modifiers": [], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c" ] }, "reaction_10745795": { "compartment": "compartment_7660", "id": "reaction_10745795", "reactome": "R-SPO-5358579", "name": "DNA polymerase delta polymerizes DNA across single stranded gap", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_30187", "species_29604", "species_29892", "species_10745793" ], "products": [ "species_5358610", "species_10729504" ], "modifiers": [ [ "species_10729489", "catalyst" ] ], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04" ] }, "reaction_10749612": { "compartment": "compartment_7660", "id": "reaction_10749612", "reactome": "R-SPO-5693598", "name": "ATM phosphorylates NBN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749597", "species_29358" ], "products": [ "species_113582", "species_10747312" ], "modifiers": [ [ "species_10749597", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10745791": { "compartment": "compartment_7660", "id": "reaction_10745791", "reactome": "R-SPO-5358525", "name": "MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5358514", "species_10745787" ], "products": [ "species_10745789" ], "modifiers": [], "additional_components": [ "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c", "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c" ] }, "reaction_10746625": { "compartment": "compartment_7660", "id": "reaction_10746625", "reactome": "R-SPO-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746613", "species_30555" ], "products": [ "species_113541", "species_10733995", "species_10733957", "species_10746622" ], "modifiers": [ [ "species_10746613", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "SPBC1347.01c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746590": { "compartment": "compartment_7660", "id": "reaction_10746590", "reactome": "R-SPO-5655481", "name": "USP1:WDR48 binds monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746430", "species_10746581" ], "products": [ "species_10746583" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q09731", "SPAC31A2.14", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10749487": { "compartment": "compartment_7660", "id": "reaction_10749487", "reactome": "R-SPO-5691001", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10749464" ], "products": [ "species_10749484", "species_113541" ], "modifiers": [ [ "species_10749464", "catalyst" ] ], "additional_components": [ "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "P87154", "SPBC25H2.13c", "O94449", "SPAC1687.03c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "Q92373", "SPCC1753.01c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04" ] }, "reaction_10750274": { "compartment": "compartment_7660", "id": "reaction_10750274", "reactome": "R-SPO-6782208", "name": "Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750269", "species_30555" ], "products": [ "species_113541", "species_10750271" ], "modifiers": [ [ "species_10750269", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c", "O94449", "SPAC1687.03c", "P36595", "SPCC1020.04c", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P49373", "SPAC20H4.03c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "P0CH07", "SPAC1805.12c", "Q09191", "SPAC23C4.15", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74635", "SPAPYUG7.04c", "C6Y4D0", "SPCC16C4.22", "P0CH06", "SPAC11G7.04", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "O13807", "SPAC17H9.10c", "Q9P7R9", "SPBC211.02c", "P26659", "SPAC1D4.12", "P87324", "SPAC27E2.05", "Q9UR24", "SPCP25A2.02c", "O13877", "SPAC1B3.12c", "Q92372", "SPBC660.13c", "Q92399", "SPBC14C8.12", "O74370", "SPBC32F12.05c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "Q9HDW3", "SPBC32F12.15", "Q09879", "SPCC188.08c", "P30261", "SPBC1734.02c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O94697", "SPBC83.14c", "O94263", "SPBP8B7.14c", "O14003", "SPAC27E2.10c", "P87123", "SPAC3A12.07", "Q9USR0", "SPBC577.09", "P37382", "SPCC1442.10c", "Q02061", "SPAC23G3.01", "O13959", "SPAC23H4.18c", "P87154", "SPBC25H2.13c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30316", "SPBC336.04", "Q92374", "SPCC23B6.05c", "O94508", "SPBC646.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "O14011", "SPAC29A4.08c", "Q9Y7V2", "SPCC645.13", "O74944", "SPCC553.07c", "O74366", "SPBC30B4.07c" ] }, "reaction_10745769": { "compartment": "compartment_7660", "id": "reaction_10745769", "reactome": "R-SPO-5358510", "name": "MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729459", "species_10745751", "species_10745765" ], "products": [ "species_10745767" ], "modifiers": [], "additional_components": [ "Q03392", "SPBC16D10.09", "P54280", "SPAC19G12.02c", "Q9P7W6", "SPBC1703.04", "O74773", "SPBC19G7.01c", "species_113592", "O74502", "SPCC285.16c", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09" ] }, "reaction_10745937": { "compartment": "compartment_7660", "id": "reaction_10745937", "reactome": "R-SPO-5444511", "name": "Formation of MSH2:MSH3 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10745756", "species_10745774" ], "products": [ "species_10745776" ], "modifiers": [], "additional_components": [ "SPBC19G7.01c", "SPAC8F11.03", "P26359", "SPAC8F11.03", "O74773", "SPBC19G7.01c", "species_29370" ] }, "reaction_10749480": { "compartment": "compartment_7660", "id": "reaction_10749480", "reactome": "R-SPO-5690996", "name": "ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10749473" ], "products": [ "species_113582", "species_113550", "species_10749477" ], "modifiers": [ [ "species_10749473", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O13807", "SPAC17H9.10c", "Q9HDW3", "SPBC32F12.15", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10747448": { "compartment": "compartment_7660", "id": "reaction_10747448", "reactome": "R-SPO-5682967", "name": "WHSC1 binds DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747437", "species_10747441" ], "products": [ "species_10747446" ], "modifiers": [], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "SPAC29B12.02c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10749607": { "compartment": "compartment_7660", "id": "reaction_10749607", "reactome": "R-SPO-5693566", "name": "TP53BP1 associates with H4K20Me2 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743694", "species_10747455" ], "products": [ "species_10747471" ], "modifiers": [], "additional_components": [ "SPBC342.05", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c" ] }, "reaction_10746597": { "compartment": "compartment_7660", "id": "reaction_10746597", "reactome": "R-SPO-5655483", "name": "USP1 autocleavage", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746581" ], "products": [ "species_10746592", "species_10746579", "species_10746594" ], "modifiers": [ [ "species_10746581", "catalyst" ] ], "additional_components": [ "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "SPBC1703.12", "SPAC31A2.14", "SPBC1703.12", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10734004": { "compartment": "compartment_7660", "id": "reaction_10734004", "reactome": "R-SPO-110311", "name": "POLZ extends translesion synthesis", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10733997" ], "products": [ "species_10734001", "species_113541", "species_10733995" ], "modifiers": [ [ "species_10733997", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749469": { "compartment": "compartment_7660", "id": "reaction_10749469", "reactome": "R-SPO-5690990", "name": "5'- incision of DNA by ERCC1:ERCC4 in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749466" ], "products": [ "species_10749281" ], "modifiers": [ [ "species_10749466", "catalyst" ] ], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c" ] }, "reaction_10747367": { "compartment": "compartment_7660", "id": "reaction_10747367", "reactome": "R-SPO-5682607", "name": "PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747350", "species_10743647" ], "products": [ "species_10743639", "species_10747364" ], "modifiers": [ [ "species_10747350", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c" ] }, "reaction_10747463": { "compartment": "compartment_7660", "id": "reaction_10747463", "reactome": "R-SPO-5683077", "name": "RNF8 and RNF168 ubiquitinate KDM4A,B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747420", "species_10729044" ], "products": [ "species_10747458", "species_10747455" ], "modifiers": [ [ "species_10747420", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O94691", "SPBC83.07", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPBC83.07", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O94691", "SPBC83.07", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c" ] }, "reaction_10747353": { "compartment": "compartment_7660", "id": "reaction_10747353", "reactome": "R-SPO-5682598", "name": "ATM phosphorylates HERC2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747346" ], "products": [ "species_113582", "species_10747350" ], "modifiers": [ [ "species_10747346", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c" ] }, "reaction_10747444": { "compartment": "compartment_7660", "id": "reaction_10747444", "reactome": "R-SPO-5682965", "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747439", "species_77087" ], "products": [ "species_10747334", "species_77502" ], "modifiers": [ [ "species_10747439", "catalyst" ] ], "additional_components": [ "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "O14079", "SPACUNK4.14", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10746428": { "compartment": "compartment_7660", "id": "reaction_10746428", "reactome": "R-SPO-5652005", "name": "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746424", "species_10746392" ], "products": [ "species_10746426" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "Q10990", "SPAC17H9.19c", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "O14122", "SPAC3A11.08", "P23566", "SPAC18B11.07c", "O74747", "SPBC1734.06", "O94449", "SPAC1687.03c", "P87154", "SPBC25H2.13c", "Q92373", "SPCC1753.01c", "P87174", "SPBC3D6.09", "O59835", "SPBC12D12.02c", "P30261", "SPBC1734.02c", "P87324", "SPAC27E2.05", "Q92374", "SPCC23B6.05c", "P30316", "SPBC336.04", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "Q09843", "SPAC23D3.02", "O14003", "SPAC27E2.10c", "O94263", "SPBP8B7.14c", "Q10990", "SPAC17H9.19c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "C6Y4D0", "SPCC16C4.22" ] }, "reaction_10747820": { "compartment": "compartment_7660", "id": "reaction_10747820", "reactome": "R-SPO-5689861", "name": "Recruitment of XPA and release of CAK ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747770", "species_10747816" ], "products": [ "species_10732457", "species_10747818" ], "modifiers": [], "additional_components": [ "SPBC649.03", "O13807", "SPAC17H9.10c", "P36613", "SPBP16F5.02", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O94684", "SPBC776.18c", "O74803", "SPBC2D10.12", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "P87235", "SPCC4G3.10c", "P26659", "SPAC1D4.12", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P0CH07", "SPAC1805.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O74803", "SPBC2D10.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749628": { "compartment": "compartment_7660", "id": "reaction_10749628", "reactome": "R-SPO-5693602", "name": "ATM recognizes H2AFX-Nucleosomes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747312", "species_10747536" ], "products": [ "species_10749602" ], "modifiers": [], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10745811": { "compartment": "compartment_7660", "id": "reaction_10745811", "reactome": "R-SPO-5358912", "name": "MSH2:MSH6 exchanges ADP for ATP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10745789" ], "products": [ "species_113582", "species_10745765" ], "modifiers": [], "additional_components": [ "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c", "O74773", "SPBC19G7.01c", "species_113592", "O74502", "SPCC285.16c" ] }, "reaction_10734026": { "compartment": "compartment_7660", "id": "reaction_10734026", "reactome": "R-SPO-110317", "name": "Insertion of correct bases opposite the lesion by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734015", "species_29604" ], "products": [ "species_113541", "species_10734023" ], "modifiers": [ [ "species_10734015", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10745939": { "compartment": "compartment_7660", "id": "reaction_10745939", "reactome": "R-SPO-5444516", "name": "Formation of MSH2:MSH6 Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113582", "species_10745756", "species_10745761" ], "products": [ "species_10745787" ], "modifiers": [], "additional_components": [ "SPBC19G7.01c", "SPCC285.16c", "O74773", "SPBC19G7.01c", "species_29370", "O74502", "SPCC285.16c" ] }, "reaction_10747482": { "compartment": "compartment_7660", "id": "reaction_10747482", "reactome": "R-SPO-5683425", "name": "ATM phosphorylates TP53BP1 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10747471" ], "products": [ "species_113582", "species_10747469" ], "modifiers": [ [ "species_10747471", "catalyst" ] ], "additional_components": [ "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P87074", "SPBC342.05", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "species_442320", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "P87074", "SPBC342.05", "O13685", "SPAC11E3.04c" ] }, "reaction_10745806": { "compartment": "compartment_7660", "id": "reaction_10745806", "reactome": "R-SPO-5358597", "name": "EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745782", "species_10745802" ], "products": [ "species_10745804" ], "modifiers": [], "additional_components": [ "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "SPBC29A10.05", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "P53695", "SPBC29A10.05" ] }, "reaction_10733831": { "compartment": "compartment_7660", "id": "reaction_10733831", "reactome": "R-SPO-109955", "name": "Formation of ERCC1:XPF heterodimeric complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733822", "species_10733827" ], "products": [ "species_10733829" ], "modifiers": [], "additional_components": [ "SPBC4F6.15c", "SPCC970.01", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c" ] }, "reaction_10734035": { "compartment": "compartment_7660", "id": "reaction_10734035", "reactome": "R-SPO-110322", "name": "Formation of Pol zeta complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733993", "species_10733988" ], "products": [ "species_10733995" ], "modifiers": [], "additional_components": [ "SPBC12D12.09", "SPAC688.10", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10" ] }, "reaction_10745809": { "compartment": "compartment_7660", "id": "reaction_10745809", "reactome": "R-SPO-5358599", "name": "EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745804", "species_10729504" ], "products": [ "species_10745793" ], "modifiers": [ [ "species_10745804", "catalyst" ] ], "additional_components": [ "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "P53695", "SPBC29A10.05", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O74773", "SPBC19G7.01c", "P54280", "SPAC19G12.02c", "species_113592", "O74502", "SPCC285.16c", "Q9P7W6", "SPBC1703.04", "Q03392", "SPBC16D10.09", "P53695", "SPBC29A10.05" ] }, "reaction_10746435": { "compartment": "compartment_7660", "id": "reaction_10746435", "reactome": "R-SPO-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733995", "species_10733980" ], "products": [ "species_10733997" ], "modifiers": [], "additional_components": [ "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746653": { "compartment": "compartment_7660", "id": "reaction_10746653", "reactome": "R-SPO-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746641", "species_30555" ], "products": [ "species_10746650", "species_113541", "species_10733957", "species_10733995" ], "modifiers": [ [ "species_10746641", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC1347.01c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10734017": { "compartment": "compartment_7660", "id": "reaction_10734017", "reactome": "R-SPO-110316", "name": "POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734013", "species_10734009" ], "products": [ "species_10734015" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC16A3.11", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746588": { "compartment": "compartment_7660", "id": "reaction_10746588", "reactome": "R-SPO-5655466", "name": "USP1:WDR48 deubiquitinates monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746583" ], "products": [ "species_10746581", "species_10729044", "species_10746585" ], "modifiers": [ [ "species_10746583", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q09731", "SPAC31A2.14", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9P7V9", "SPBC1703.12", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94697", "SPBC83.14c", "O94449", "SPAC1687.03c", "Q09843", "SPAC23D3.02", "Q92373", "SPCC1753.01c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q92374", "SPCC23B6.05c", "Q03392", "SPBC16D10.09", "Q92372", "SPBC660.13c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q09731", "SPAC31A2.14", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10746564": { "compartment": "compartment_7660", "id": "reaction_10746564", "reactome": "R-SPO-5654985", "name": "SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746544", "species_10746560" ], "products": [ "species_10746562" ], "modifiers": [], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O42915", "SPBC16A3.09c", "Q9P3A7", "SPAC1565.08", "Q9P780", "SPBC1711.10c", "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10733983": { "compartment": "compartment_7660", "id": "reaction_10733983", "reactome": "R-SPO-110308", "name": "REV1 inserts dCMP opposite to AP sites in DNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30185", "species_10733972" ], "products": [ "species_10733980" ], "modifiers": [ [ "species_10733972", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749609": { "compartment": "compartment_7660", "id": "reaction_10749609", "reactome": "R-SPO-5693583", "name": "MDC1 associates with gamma-H2AFX at nuclear foci", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747435", "species_10749590" ], "products": [ "species_10749592" ], "modifiers": [], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14079", "SPACUNK4.14", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10749471": { "compartment": "compartment_7660", "id": "reaction_10749471", "reactome": "R-SPO-5690991", "name": "Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747788", "species_10733829" ], "products": [ "species_10749466" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "P36617", "SPCC970.01", "Q06182", "SPBC4F6.15c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P36617", "SPCC970.01", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "Q06182", "SPBC4F6.15c" ] }, "reaction_10747423": { "compartment": "compartment_7660", "id": "reaction_10747423", "reactome": "R-SPO-5682858", "name": "RNF8 and RNF168 ubiquitinate H2AFX", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747398", "species_10729044" ], "products": [ "species_10747420" ], "modifiers": [ [ "species_10747398", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "O94691", "SPBC83.07", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c", "P09322", "SPAC1834.03c", "species_442320", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "P04909", "SPCC622.08c", "O94451", "SPAC1687.05", "O14026", "SPAC29B12.02c", "O13351", "SPBC365.06", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "O74983", "SPCC338.05c", "O13685", "SPAC11E3.04c" ] }, "reaction_10746616": { "compartment": "compartment_7660", "id": "reaction_10746616", "reactome": "R-SPO-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746605", "species_30555" ], "products": [ "species_10746613", "species_113541" ], "modifiers": [ [ "species_10746605", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "Q0E7J8", "SPBC12D12.09", "P0C8R3", "SPAC589.10c", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "Q0E7J8", "SPBC12D12.09", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "species_29926", "O94623", "SPBC1347.01c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "Q0E7J8", "SPBC12D12.09", "P0C8R3", "SPAC589.10c", "Q9P6L6", "SPAC688.10", "O14003", "SPAC27E2.10c", "O74944", "SPCC553.07c", "O60182", "SPBC23E6.07c", "species_113527", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10749977": { "compartment": "compartment_7660", "id": "reaction_10749977", "reactome": "R-SPO-5696465", "name": "USP45 deubiquitinates ERCC1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10749972" ], "products": [ "species_10733822", "species_10729044" ], "modifiers": [ [ "species_10749974", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q06182", "SPBC4F6.15c", "SPBC4F6.15c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "SPAC23G3.08c" ] }, "reaction_10734033": { "compartment": "compartment_7660", "id": "reaction_10734033", "reactome": "R-SPO-110319", "name": "Elongation by POLH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30555", "species_10734023" ], "products": [ "species_10734030", "species_113541" ], "modifiers": [ [ "species_10734023", "catalyst" ] ], "additional_components": [ "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "Q09843", "SPAC23D3.02", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10746569": { "compartment": "compartment_7660", "id": "reaction_10746569", "reactome": "R-SPO-5654989", "name": "SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746562", "species_29358" ], "products": [ "species_113582", "species_10746566", "species_10734009" ], "modifiers": [ [ "species_10746562", "catalyst" ] ], "additional_components": [ "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04", "SPBC16A3.11", "O42915", "SPBC16A3.09c", "O94449", "SPAC1687.03c", "Q92373", "SPCC1753.01c", "Q9P3A7", "SPAC1565.08", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O94697", "SPBC83.14c", "P0CH07", "SPAC1805.12c", "O42917", "SPBC16A3.11", "P0C016", "SPAC6G10.11c", "Q09843", "SPAC23D3.02", "P0C8R3", "SPAC589.10c", "O14003", "SPAC27E2.10c", "Q9P780", "SPBC1711.10c", "O60182", "SPBC23E6.07c", "Q03392", "SPBC16D10.09", "P0CH06", "SPAC11G7.04" ] }, "reaction_10747453": { "compartment": "compartment_7660", "id": "reaction_10747453", "reactome": "R-SPO-5682992", "name": "KDM4A,B bind H4K20Me2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747336", "species_10747334" ], "products": [ "species_10747340" ], "modifiers": [], "additional_components": [ "SPBC83.07", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "O14026", "SPAC29B12.02c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O14079", "SPACUNK4.14", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O94691", "SPBC83.07", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10747790": { "compartment": "compartment_7660", "id": "reaction_10747790", "reactome": "R-SPO-5689317", "name": "Formation of the pre-incision complex in GG-NER", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747786", "species_10747765", "species_10729504" ], "products": [ "species_10747788" ], "modifiers": [], "additional_components": [ "O13807", "SPAC17H9.10c", "O13768", "SPAC17A5.06", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P26659", "SPAC1D4.12", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c", "O74995", "SPCC1682.07", "SPBC3E7.08c", "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O13807", "SPAC17H9.10c", "O13959", "SPAC23H4.18c", "Q9HDW3", "SPBC32F12.15", "O14122", "SPAC3A11.08", "Q92373", "SPCC1753.01c", "P26659", "SPAC1D4.12", "Q92374", "SPCC23B6.05c", "O74995", "SPCC1682.07", "Q92372", "SPBC660.13c", "O13768", "SPAC17A5.06", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P28706", "SPBC3E7.08c", "O59753", "SPBC649.03", "O74366", "SPBC30B4.07c" ] }, "reaction_10749605": { "compartment": "compartment_7660", "id": "reaction_10749605", "reactome": "R-SPO-5693549", "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10749602" ], "products": [ "species_113582", "species_10747546" ], "modifiers": [ [ "species_10749602", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "P04913", "SPCC622.09", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "P04909", "SPCC622.08c" ] }, "reaction_10743005": { "compartment": "compartment_5460", "id": "reaction_10743005", "reactome": "R-SPO-2162253", "name": "FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162256", "species_2162257" ], "products": [ "species_2162214", "species_159450" ], "modifiers": [ [ "species_10743002", "catalyst" ] ], "additional_components": [ "O13851", "SPAC19G12.12", "species_29926", "O43091", "SPBPJ4664.01" ] }, "reaction_10742984": { "compartment": "compartment_5460", "id": "reaction_10742984", "reactome": "R-SPO-2162193", "name": "DHDB is methylated to MHDB by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162209", "species_2162265" ], "products": [ "species_2162252", "species_2162215", "species_113529" ], "modifiers": [ [ "species_10742970", "catalyst" ] ], "additional_components": [ "SPCC162.05" ] }, "reaction_10742973": { "compartment": "compartment_5460", "id": "reaction_10742973", "reactome": "R-SPO-2162186", "name": "DeMQ10H2 is methylated to Q10H2 by COQ3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162212", "species_2162265" ], "products": [ "species_2162252", "species_2162198", "species_113529" ], "modifiers": [ [ "species_10742970", "catalyst" ] ], "additional_components": [ "SPCC162.05" ] }, "reaction_10742981": { "compartment": "compartment_70616", "id": "reaction_10742981", "reactome": "R-SPO-2162192", "name": "PHB and all-E-10PrP2 are combined into DHB by COQ2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2162214", "species_2162213" ], "products": [ "species_2162207", "species_159450" ], "modifiers": [ [ "species_10742978", "catalyst" ] ], "additional_components": [ "SPBC3F6.01c" ] }, "reaction_10734456": { "compartment": "compartment_7660", "id": "reaction_10734456", "reactome": "R-SPO-112430", "name": "Formation of P-TEFb complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734280", "species_10734258" ], "products": [ "species_10734282" ], "modifiers": [], "additional_components": [ "O74627", "SPBC32F12.06", "O59748", "SPBC530.13", "SPAC2F3.15", "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15", "O59748", "SPBC530.13" ] }, "reaction_10734442": { "compartment": "compartment_7660", "id": "reaction_10734442", "reactome": "R-SPO-112392", "name": "Resumption of elongation after recovery from pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734440" ], "products": [ "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734458": { "compartment": "compartment_7660", "id": "reaction_10734458", "reactome": "R-SPO-112434", "name": "Formation of DSIF complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733600", "species_10734297" ], "products": [ "species_10734299" ], "modifiers": [], "additional_components": [ "SPAC23C4.19", "SPBC21C3.16c", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19" ] }, "reaction_10733342": { "compartment": "compartment_7660", "id": "reaction_10733342", "reactome": "R-SPO-75862", "name": "Fall Back to Closed Pre-initiation Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733332" ], "products": [ "species_10733340" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10734468": { "compartment": "compartment_7660", "id": "reaction_10734468", "reactome": "R-SPO-113413", "name": "TFIIS-mediated recovery of elongation from arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734454": { "compartment": "compartment_7660", "id": "reaction_10734454", "reactome": "R-SPO-112429", "name": "Formation of FACT complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734357", "species_10734352" ], "products": [ "species_10734359" ], "modifiers": [], "additional_components": [ "SPBP8B7.19", "SPBC609.05", "O94529", "SPBC609.05", "O94267", "SPBP8B7.19" ] }, "reaction_10734462": { "compartment": "compartment_7660", "id": "reaction_10734462", "reactome": "R-SPO-113409", "name": "Abortive termination of early transcription elongation by DSIF:NELF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734367" ], "products": [ "species_10734367" ], "modifiers": [], "additional_components": [ "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13936", "SPAC23C4.19", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13936", "SPAC23C4.19", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10732715": { "compartment": "compartment_7660", "id": "reaction_10732715", "reactome": "R-SPO-73946", "name": "Abortive initiation after formation of the first phosphodiester bond", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732713" ], "products": [ "species_109877", "species_10732699", "species_10732619", "species_10732494", "species_10732624", "species_10732711", "species_10730708" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "SPAC16E8.16", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10733330": { "compartment": "compartment_7660", "id": "reaction_10733330", "reactome": "R-SPO-75856", "name": "Abortive Initiation Before Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733328" ], "products": [ "species_110068", "species_10732699", "species_10732619", "species_10732494", "species_10732624", "species_10732711", "species_10730708" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "SPAC16E8.16", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10734446": { "compartment": "compartment_7660", "id": "reaction_10734446", "reactome": "R-SPO-112395", "name": "Abortive termination of elongation after arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734444" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734464": { "compartment": "compartment_7660", "id": "reaction_10734464", "reactome": "R-SPO-113411", "name": "2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734440" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734470": { "compartment": "compartment_7660", "id": "reaction_10734470", "reactome": "R-SPO-113414", "name": "7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734436" ], "products": [ "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10733400": { "compartment": "compartment_7660", "id": "reaction_10733400", "reactome": "R-SPO-75891", "name": "Abortive Initiation After Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733398" ], "products": [ "species_75897", "species_10732494", "species_10732711", "species_10730708" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10737527": { "compartment": "compartment_70101", "id": "reaction_10737527", "reactome": "R-SPO-209792", "name": "N-acetylation of serotonin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76183", "species_209914" ], "products": [ "species_76194", "species_209793" ], "modifiers": [ [ "species_10737524", "catalyst" ] ], "additional_components": [ "SPAC9.02c" ] }, "reaction_10741986": { "compartment": "compartment_12045", "id": "reaction_10741986", "reactome": "R-SPO-1482816", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[6]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741994": { "compartment": "compartment_12045", "id": "reaction_10741994", "reactome": "R-SPO-1482827", "name": "PC is hydrolyzed to 2-acyl LPC by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742013": { "compartment": "compartment_12045", "id": "reaction_10742013", "reactome": "R-SPO-1482862", "name": "PC is hydrolysed to 2-acyl LPC by PLA2[7]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_975614", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741810": { "compartment": "compartment_12045", "id": "reaction_10741810", "reactome": "R-SPO-1482547", "name": "1-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741770": { "compartment": "compartment_12045", "id": "reaction_10741770", "reactome": "R-SPO-1482533", "name": "2-acyl LPC is acylated to PC by LPCAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_1500578" ], "products": [ "species_76194", "species_426925" ], "modifiers": [ [ "species_10741765", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10742007": { "compartment": "compartment_12045", "id": "reaction_10742007", "reactome": "R-SPO-1482856", "name": "PC is hydrolyzed to 1-acyl LPC by PLA2[5]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_1524028", "species_1524021" ], "modifiers": [ [ "species_10742004", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10738121": { "compartment": "compartment_5460", "id": "reaction_10738121", "reactome": "R-SPO-380608", "name": "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_380598", "species_113526" ], "products": [ "species_380593", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730539", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10742179": { "compartment": "compartment_70101", "id": "reaction_10742179", "reactome": "R-SPO-1497796", "name": "BH2 binding can lead to eNOS uncoupling", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737053", "species_1497857" ], "products": [ "species_29870", "species_10742177" ], "modifiers": [], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "P36587", "SPBC29A10.01", "species_29870", "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_1497857", "species_29870", "P36587", "SPBC29A10.01" ] }, "reaction_10741760": { "compartment": "compartment_70101", "id": "reaction_10741760", "reactome": "R-SPO-1474146", "name": "GCH1 reduces GTP to dihydroneopterin triphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_29356" ], "products": [ "species_1474124", "species_29460" ], "modifiers": [ [ "species_10741757", "catalyst" ], [ "species_29502", "catalyst" ], [ "species_29870", "inhibitor" ] ], "additional_components": [ "O13774", "SPAC17A5.13" ] }, "reaction_10735967": { "compartment": "compartment_5460", "id": "reaction_10735967", "reactome": "R-SPO-189465", "name": "FECH binds Fe2+ to PRIN9 to form heme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189487", "species_113531" ], "products": [ "species_189444", "species_113529" ], "modifiers": [ [ "species_10735964", "catalyst" ], [ "species_391232", "inhibitor" ] ], "additional_components": [ "O59786", "SPCC320.09" ] }, "reaction_10735899": { "compartment": "compartment_70101", "id": "reaction_10735899", "reactome": "R-SPO-189406", "name": "4 PBGs bind to form HMB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189464", "species_29356" ], "products": [ "species_189449", "species_31633" ], "modifiers": [ [ "species_10735896", "catalyst" ] ], "additional_components": [ "CHEBI:36319", "Q09899", "SPAC24B11.13" ] }, "reaction_10747163": { "compartment": "compartment_70101", "id": "reaction_10747163", "reactome": "R-SPO-5679041", "name": "ABCC2 transports BMG,BDG from cytosol to extracellular region", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_5679042", "species_29356" ], "products": [ "species_29370", "species_5679034", "species_29372" ], "modifiers": [ [ "species_10741710", "catalyst" ] ], "additional_components": [ "CHEBI:16427", "CHEBI:18392", "CHEBI:16427", "CHEBI:18392", "Q10185", "SPAC3F10.11c", "Q9P5N0", "SPBC359.05" ] }, "reaction_10735981": { "compartment": "compartment_70101", "id": "reaction_10735981", "reactome": "R-SPO-190182", "name": "UROD decarboxylates URO1 to COPRO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_190157" ], "products": [ "species_113528", "species_190128" ], "modifiers": [ [ "species_10735926", "catalyst" ] ], "additional_components": [ "Q9USJ5", "SPCC4B3.05c" ] }, "reaction_10735909": { "compartment": "compartment_17927", "id": "reaction_10735909", "reactome": "R-SPO-189421", "name": "CPO transforms COPRO3 to PPGEN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189411", "species_189461" ], "products": [ "species_189481", "species_189480", "species_189478" ], "modifiers": [ [ "species_10735906", "catalyst" ] ], "additional_components": [ "Q9UTE2", "SPAC222.11" ] }, "reaction_10735939": { "compartment": "compartment_70101", "id": "reaction_10735939", "reactome": "R-SPO-189439", "name": "ALAD condenses 2 dALAs to form PBG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189489" ], "products": [ "species_70106", "species_189464", "species_29356" ], "modifiers": [ [ "species_10735936", "catalyst" ] ], "additional_components": [ "P78974", "SPAC1805.06c", "species_442320" ] }, "reaction_10735975": { "compartment": "compartment_70101", "id": "reaction_10735975", "reactome": "R-SPO-189488", "name": "UROS transforms HMB to URO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189449" ], "products": [ "species_189407", "species_29356" ], "modifiers": [ [ "species_10735972", "catalyst" ] ], "additional_components": [ "SPAC31G5.08" ] }, "reaction_10735929": { "compartment": "compartment_70101", "id": "reaction_10735929", "reactome": "R-SPO-189425", "name": "UROD decarboxylates URO3 to COPRO3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189407" ], "products": [ "species_113528", "species_189455" ], "modifiers": [ [ "species_10735926", "catalyst" ] ], "additional_components": [ "Q9USJ5", "SPCC4B3.05c" ] }, "reaction_10743681": { "compartment": "compartment_5460", "id": "reaction_10743681", "reactome": "R-SPO-2995330", "name": "COX10 transforms heme to heme O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_2162257", "species_189444" ], "products": [ "species_2995328", "species_159450" ], "modifiers": [ [ "species_10743678", "catalyst" ] ], "additional_components": [ "SPBC365.02c" ] }, "reaction_10735957": { "compartment": "compartment_5460", "id": "reaction_10735957", "reactome": "R-SPO-189442", "name": "ALAS condenses SUCC-CoA and Gly to form dALA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70958", "species_159549", "species_113529" ], "products": [ "species_29374", "species_189466", "species_29376" ], "modifiers": [ [ "species_10735954", "catalyst" ], [ "species_189444", "inhibitor" ] ], "additional_components": [ "O14092", "SPAC2F3.09" ] }, "reaction_10735979": { "compartment": "compartment_70101", "id": "reaction_10735979", "reactome": "R-SPO-190141", "name": "ALAD binds to Pb2+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735936", "species_190173" ], "products": [ "species_29426", "species_10735977" ], "modifiers": [], "additional_components": [ "P78974", "SPAC1805.06c", "species_442320", "P78974", "SPAC1805.06c", "species_442320", "species_190173" ] }, "reaction_10735919": { "compartment": "compartment_17927", "id": "reaction_10735919", "reactome": "R-SPO-189423", "name": "PPO oxidises PPGEN9 to PRIN9", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189461", "species_189478" ], "products": [ "species_189481", "species_189463" ], "modifiers": [ [ "species_10735916", "catalyst" ] ], "additional_components": [ "Q10062", "SPAC1F5.07c", "species_113596" ] }, "reaction_10757699": { "compartment": "compartment_70101", "id": "reaction_10757699", "reactome": "R-SPO-9661405", "name": "ABCC1 transports BIL from cytosol to extracellular region (blood)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_189386" ], "products": [ "species_9661418" ], "modifiers": [ [ "species_10737726", "catalyst" ] ], "additional_components": [ "SPAC3F10.11c" ] }, "reaction_10743689": { "compartment": "compartment_5460", "id": "reaction_10743689", "reactome": "R-SPO-2995334", "name": "COX15 transforms heme O to heme A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2995328" ], "products": [ "species_2995348" ], "modifiers": [ [ "species_10743686", "catalyst" ] ], "additional_components": [ "SPAC22E12.10c" ] }, "reaction_10757253": { "compartment": "compartment_17947", "id": "reaction_10757253", "reactome": "R-SPO-9603784", "name": "PEX19:class I PMP binds PEX3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757231", "species_10738205" ], "products": [ "species_10757233" ], "modifiers": [], "additional_components": [ "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14136", "SPAC3C7.10", "SPAC29A4.14c", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14017", "SPAC29A4.14c", "O14136", "SPAC3C7.10" ] }, "reaction_10757255": { "compartment": "compartment_70101", "id": "reaction_10757255", "reactome": "R-SPO-9603804", "name": "PEX19 binds class I peroxisomal membrane proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757189", "species_10757229" ], "products": [ "species_10757231" ], "modifiers": [], "additional_components": [ "SPAC17C9.14", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "O14136", "SPAC3C7.10", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14136", "SPAC3C7.10" ] }, "reaction_10757251": { "compartment": "compartment_17947", "id": "reaction_10757251", "reactome": "R-SPO-9603775", "name": "PEX3:PEX19:class I PMP dissociates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757233" ], "products": [ "species_10757189", "species_10757249", "species_10738205" ], "modifiers": [], "additional_components": [ "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "Q10485", "SPAC17C9.14", "O14017", "SPAC29A4.14c", "O14136", "SPAC3C7.10", "SPAC17C9.14", "O94516", "SPBC646.15c", "O60065", "SPBC13G1.03c", "Q10333", "SPBC582.09", "Q9P7J5", "SPCC24B10.10c", "O14142", "SPAC3G6.05", "Q9USZ8", "SPBC11G11.01", "Q8TFH8", "SPAPB17E12.03", "Q10244", "SPAC4G9.14", "O14136", "SPAC3C7.10", "SPAC29A4.14c" ] }, "reaction_10738119": { "compartment": "compartment_374932", "id": "reaction_10738119", "reactome": "R-SPO-380586", "name": "loading of Serotonin in synaptic vesicles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_209914" ], "products": [ "species_380585" ], "modifiers": [ [ "species_10737993", "catalyst" ] ], "additional_components": [ "SPCC18.02" ] }, "reaction_10757333": { "compartment": "compartment_70101", "id": "reaction_10757333", "reactome": "R-SPO-9619376", "name": "CAMK1 binds calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737034", "species_10757329" ], "products": [ "species_10757331" ], "modifiers": [], "additional_components": [ "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "SPACUNK12.02c", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9P7I2", "SPACUNK12.02c" ] }, "reaction_10757822": { "compartment": "compartment_876", "id": "reaction_10757822", "reactome": "R-SPO-9679775", "name": "COMT binds COMT Inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9679778", "species_10738036" ], "products": [ "species_10738039" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=6646", "LigandDisplayForward?ligandId=6647", "LigandDisplayForward?ligandId=8988", "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6646", "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6647", "LigandDisplayForward?ligandId=8988" ] }, "reaction_10738044": { "compartment": "compartment_70101", "id": "reaction_10738044", "reactome": "R-SPO-379464", "name": "COMT transfers Met to DOPAC to form HVA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9677997", "species_71284" ], "products": [ "species_174369", "species_9677992" ], "modifiers": [ [ "species_10738036", "catalyst" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c" ] }, "reaction_10738041": { "compartment": "compartment_70101", "id": "reaction_10738041", "reactome": "R-SPO-379387", "name": "COMT transfers Met to DA to form 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159362", "species_71284" ], "products": [ "species_71285", "species_8954997" ], "modifiers": [ [ "species_10738036", "catalyst" ], [ "species_10738039", "inhibitor" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6646", "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c", "LigandDisplayForward?ligandId=6647", "LigandDisplayForward?ligandId=8988" ] }, "reaction_10737996": { "compartment": "compartment_374932", "id": "reaction_10737996", "reactome": "R-SPO-372542", "name": "Loading of dopamine into synaptic veiscles", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159362" ], "products": [ "species_351601" ], "modifiers": [ [ "species_10737993", "catalyst" ] ], "additional_components": [ "SPCC18.02" ] }, "reaction_10757324": { "compartment": "compartment_70101", "id": "reaction_10757324", "reactome": "R-SPO-9619355", "name": "CaMKK autophosphorylates in the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10757317" ], "products": [ "species_29370", "species_10757321" ], "modifiers": [ [ "species_10757317", "catalyst" ] ], "additional_components": [ "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "Q9UU87", "SPCC1919.01", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05" ] }, "reaction_10756407": { "compartment": "compartment_70101", "id": "reaction_10756407", "reactome": "R-SPO-8955010", "name": "LRTOMT transfers Met to DA, forming 3MT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_159362", "species_71284" ], "products": [ "species_71285", "species_8954997" ], "modifiers": [ [ "species_10756404", "catalyst" ] ], "additional_components": [ "Q8NKC1", "SPBPB21E7.04c", "O42898", "SPBPB21E7.04c" ] }, "reaction_10757358": { "compartment": "compartment_876", "id": "reaction_10757358", "reactome": "R-SPO-9625814", "name": "SPHK1 phosphorylates sphingosine in response to E2 stimulation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1606609" ], "products": [ "species_5218688" ], "modifiers": [ [ "species_10738404", "catalyst" ] ], "additional_components": [ "SPAC4A8.07c" ] }, "reaction_10737078": { "compartment": "compartment_20699", "id": "reaction_10737078", "reactome": "R-SPO-202132", "name": "depalmitoylated eNOS translocates from plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737066" ], "products": [ "species_10737076" ], "modifiers": [], "additional_components": [ "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_29870", "species_113596", "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_29870", "species_113596" ] }, "reaction_10737226": { "compartment": "compartment_20699", "id": "reaction_10737226", "reactome": "R-SPO-203700", "name": "eNOS translocation from Golgi to Caveolae", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737196" ], "products": [ "species_10736995" ], "modifiers": [], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_113596" ] }, "reaction_10737204": { "compartment": "compartment_20699", "id": "reaction_10737204", "reactome": "R-SPO-203567", "name": "palmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737064", "species_200993" ], "products": [ "species_10737196" ], "modifiers": [ [ "species_10737201", "catalyst" ] ], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "SPBC3H7.09" ] }, "reaction_10737214": { "compartment": "compartment_70101", "id": "reaction_10737214", "reactome": "R-SPO-203611", "name": "N-myristoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737212", "species_184174" ], "products": [ "species_10737064" ], "modifiers": [], "additional_components": [ "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01", "Q9US28", "SPBC12C2.03c", "Q09744", "SPBC12C2.03c", "P36587", "SPBC29A10.01" ] }, "reaction_10737224": { "compartment": "compartment_876", "id": "reaction_10737224", "reactome": "R-SPO-203613", "name": "depalmitoylation of eNOS", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736995" ], "products": [ "species_76168", "species_10737066" ], "modifiers": [ [ "species_10737221", "catalyst" ] ], "additional_components": [ "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_113596", "species_442320", "Q9US28", "SPBC12C2.03c", "species_73524", "Q09744", "SPBC12C2.03c", "species_189444", "P36587", "SPBC29A10.01", "species_29870", "species_113596", "O42881", "SPAC8E11.04c" ] }, "reaction_10742182": { "compartment": "compartment_70101", "id": "reaction_10742182", "reactome": "R-SPO-1497810", "name": "Uncoupled eNOS favours the formation of superoxide", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29364", "species_29368" ], "products": [ "species_29366", "species_1222424" ], "modifiers": [ [ "species_10742177", "catalyst" ] ], "additional_components": [ "species_442320", "P05933", "SPAC3A12.14", "Q9US28", "SPBC12C2.03c", "species_74016", "species_189444", "Q09744", "SPBC12C2.03c", "O14008", "SPAC29A4.05", "species_113596", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P41887", "SPAC926.04c", "species_73524", "species_1497857", "species_29870", "P36587", "SPBC29A10.01" ] }, "reaction_10740054": { "compartment": "compartment_876", "id": "reaction_10740054", "reactome": "R-SPO-481044", "name": "Surface deployment of platelet alpha granule membrane components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740042" ], "products": [ "species_10740052" ], "modifiers": [], "additional_components": [ "O74557", "SPCC970.03", "O13809", "SPAC17H9.12c", "P87178", "SPBC3D6.13c", "O74557", "SPCC970.03", "O13809", "SPAC17H9.12c", "P87178", "SPBC3D6.13c" ] }, "reaction_10734544": { "compartment": "compartment_70101", "id": "reaction_10734544", "reactome": "R-SPO-114553", "name": "Activation of conventional Protein Kinase C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734522", "species_74016", "species_33625", "species_114519" ], "products": [ "species_10734542" ], "modifiers": [ [ "species_114519", "catalyst" ] ], "additional_components": [ "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c", "species_1500646", "P36583", "SPBC12D12.04c", "species_74016", "species_1500596", "P36582", "SPAC17G8.14c" ] }, "reaction_10740115": { "compartment": "compartment_70101", "id": "reaction_10740115", "reactome": "R-SPO-482772", "name": "Release of platelet cytosolic components", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740085" ], "products": [ "species_10740113" ], "modifiers": [], "additional_components": [ "O94590", "SPCC584.05", "P28758", "SPAC821.10c", "P04689", "SPBC800.05c", "P05933", "SPAC3A12.14", "O60054", "SPBC56F2.03", "O14008", "SPAC29A4.05", "P04688", "SPBC16A3.15c", "P10989", "SPBC32H8.12c", "O42914", "SPBC16A3.08c", "O14301", "SPAC9G1.05", "O94590", "SPCC584.05", "P28758", "SPAC821.10c", "P04689", "SPBC800.05c", "P05933", "SPAC3A12.14", "O60054", "SPBC56F2.03", "O14008", "SPAC29A4.05", "P04688", "SPBC16A3.15c", "P10989", "SPBC32H8.12c", "O42914", "SPBC16A3.08c", "O14301", "SPAC9G1.05" ] }, "reaction_10740026": { "compartment": "compartment_876", "id": "reaction_10740026", "reactome": "R-SPO-481009", "name": "Exocytosis of platelet dense granule content", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740020" ], "products": [ "species_10740024" ], "modifiers": [], "additional_components": [ "O94740", "SPBC9B6.10", "species_29372", "species_74016", "species_113592", "species_29370", "species_111294", "CHEBI:15996", "species_111349", "species_29926", "species_209914", "species_29420", "O94740", "SPBC9B6.10", "species_29372", "species_74016", "species_113592", "species_29370", "species_29438", "species_111294", "species_29926", "species_209914" ] }, "reaction_10739124": { "compartment": "compartment_114584", "id": "reaction_10739124", "reactome": "R-SPO-429157", "name": "ABCC4 accumulation of dense granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29370", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29372", "species_114565" ], "modifiers": [ [ "species_10739121", "catalyst" ] ], "additional_components": [ "Q92337", "SPAC9E9.12c", "Q9P7V2", "SPAC30.04c" ] }, "reaction_10740013": { "compartment": "compartment_876", "id": "reaction_10740013", "reactome": "R-SPO-481007", "name": "Exocytosis of platelet alpha granule contents", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10739997" ], "products": [ "species_10740011" ], "modifiers": [], "additional_components": [ "P78768", "SPBC3B9.10", "O13998", "SPAC27E2.03c", "O13728", "SPAC15A10.08", "Q9Y7U4", "SPCC645.04", "P78768", "SPBC3B9.10", "O13998", "SPAC27E2.03c", "O13728", "SPAC15A10.08", "Q9Y7U4", "SPCC645.04" ] }, "reaction_10736228": { "compartment": "compartment_984", "id": "reaction_10736228", "reactome": "R-SPO-192430", "name": "Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_171126", "species_109276" ], "products": [ "species_174602", "species_174675" ], "modifiers": [ [ "species_10736220", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "Q8TFG4", "SPAPB18E9.04c", "CHEBI:16755", "CHEBI:16359", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274" ] }, "reaction_10755696": { "compartment": "compartment_984", "id": "reaction_10755696", "reactome": "R-SPO-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878780", "species_109276" ], "products": [ "species_109277", "species_8878776" ], "modifiers": [ [ "species_10755693", "catalyst" ] ], "additional_components": [ "species_442320", "O60109", "SPBC14F5.13c", "species_74016" ] }, "reaction_10736223": { "compartment": "compartment_984", "id": "reaction_10736223", "reactome": "R-SPO-192417", "name": "Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_171076" ], "products": [ "species_174602", "species_171149" ], "modifiers": [ [ "species_10736220", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "Q8TFG4", "SPAPB18E9.04c", "CHEBI:16755", "CHEBI:16359", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274" ] }, "reaction_10736226": { "compartment": "compartment_984", "id": "reaction_10736226", "reactome": "R-SPO-192425", "name": "Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_109276", "species_6814795" ], "products": [ "species_192438", "species_174602" ], "modifiers": [ [ "species_10736220", "catalyst" ] ], "additional_components": [ "CHEBI:17687", "Q8TFG4", "SPAPB18E9.04c", "CHEBI:16755", "CHEBI:16359", "CHEBI:9407", "CHEBI:28865", "CHEBI:36274" ] }, "reaction_10757949": { "compartment": "compartment_70101", "id": "reaction_10757949", "reactome": "R-SPO-9696275", "name": "RND2 binds GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757914" ], "products": [ "species_10757916" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10740224": { "compartment": "compartment_70101", "id": "reaction_10740224", "reactome": "R-SPO-548831", "name": "TECR,TECRL dehydrogenate TOD-CoA to ST-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_548809" ], "products": [ "species_29366", "species_428139" ], "modifiers": [ [ "species_10740221", "catalyst" ] ], "additional_components": [ "O94511", "SPBC646.07c" ] }, "reaction_10740231": { "compartment": "compartment_70101", "id": "reaction_10740231", "reactome": "R-SPO-548843", "name": "ACSL3,4 ligate CoA to AA to form AA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_29768", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_548819" ], "modifiers": [ [ "species_10740228", "catalyst" ] ], "additional_components": [ "Q9P7D7", "SPBP4H10.11c", "O60135", "SPBC18H10.02" ] }, "reaction_10747097": { "compartment": "compartment_12045", "id": "reaction_10747097", "reactome": "R-SPO-5676637", "name": "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5676631" ], "products": [ "species_5676634", "species_29356" ], "modifiers": [ [ "species_10747094", "catalyst" ] ], "additional_components": [ "O14346", "SPBC19C2.15c" ] }, "reaction_10736922": { "compartment": "compartment_70101", "id": "reaction_10736922", "reactome": "R-SPO-201035", "name": "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_3632881", "species_113592" ], "products": [ "species_111294", "species_76577", "species_29356", "species_200993" ], "modifiers": [ [ "species_10736919", "catalyst" ] ], "additional_components": [ "Q9P7D7", "SPBP4H10.11c", "O60135", "SPBC18H10.02" ] }, "reaction_10738479": { "compartment": "compartment_876", "id": "reaction_10738479", "reactome": "R-SPO-399998", "name": "Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_179856" ], "products": [ "species_114520", "species_114519" ], "modifiers": [ [ "species_10738476", "catalyst" ] ], "additional_components": [ "P40977", "SPAC22F8.11", "species_29438", "Q04665", "SPAC23H3.13c" ] }, "reaction_10734981": { "compartment": "compartment_7660", "id": "reaction_10734981", "reactome": "R-SPO-163664", "name": "AMP binds to gamma subunit of AMP kinase heterotrimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_164121", "species_10734975" ], "products": [ "species_10734979" ], "modifiers": [], "additional_components": [ "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c", "species_76577", "Q10343", "SPAC1556.08c", "O74536", "SPCC74.03c", "P78789", "SPCC1919.03c" ] }, "reaction_10733346": { "compartment": "compartment_7660", "id": "reaction_10733346", "reactome": "R-SPO-75864", "name": "Newly Formed Phosphodiester Bond Stabilized and PPi Released", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733344" ], "products": [ "species_10732713", "species_113541" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10733338": { "compartment": "compartment_7660", "id": "reaction_10733338", "reactome": "R-SPO-75861", "name": "NTP Binds Active Site of RNA Polymerase II", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733332" ], "products": [ "species_10733336" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10733348": { "compartment": "compartment_7660", "id": "reaction_10733348", "reactome": "R-SPO-75866", "name": "Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733336" ], "products": [ "species_10733344" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c" ] }, "reaction_10743710": { "compartment": "compartment_7660", "id": "reaction_10743710", "reactome": "R-SPO-2997723", "name": "PIAS4 SUMOylates TP53BP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743694", "species_10743647" ], "products": [ "species_10743639", "species_10743702" ], "modifiers": [ [ "species_10743707", "catalyst" ] ], "additional_components": [ "SPBC342.05", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P87074", "SPBC342.05", "SPAC1687.05" ] }, "reaction_10744668": { "compartment": "compartment_7660", "id": "reaction_10744668", "reactome": "R-SPO-3968414", "name": "UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744646" ], "products": [ "species_10743639", "species_10744663" ], "modifiers": [ [ "species_10744665", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O43058", "SPBC4C3.12", "O13606", "SPBC32H8.11", "SPAC30D11.13", "O43058", "SPBC4C3.12", "O13606", "SPBC32H8.11", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O94451", "SPAC1687.05" ] }, "reaction_10751307": { "compartment": "compartment_7660", "id": "reaction_10751307", "reactome": "R-SPO-6798372", "name": "ATM phosphorylates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10751295" ], "products": [ "species_113582", "species_10751305" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "SPCC23B6.03c" ] }, "reaction_10751322": { "compartment": "compartment_7660", "id": "reaction_10751322", "reactome": "R-SPO-6798373", "name": "MDM2 ubiquitinates DYRK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751295", "species_10729044" ], "products": [ "species_10751315" ], "modifiers": [ [ "species_10751319", "catalyst" ] ], "additional_components": [ "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09815", "SPAC16C9.07", "Q09690", "SPAC2F7.03c", "O74503", "SPCC285.17" ] }, "reaction_10752579": { "compartment": "compartment_7660", "id": "reaction_10752579", "reactome": "R-SPO-6805061", "name": "CK2 binds FACT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734359", "species_10752575" ], "products": [ "species_10752577" ], "modifiers": [], "additional_components": [ "O94529", "SPBC609.05", "O94267", "SPBP8B7.19", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11", "P40232", "SPAC1851.03", "P40231", "SPAC23C11.11", "O94529", "SPBC609.05", "O94267", "SPBP8B7.19" ] }, "reaction_10745446": { "compartment": "compartment_13231", "id": "reaction_10745446", "reactome": "R-SPO-5221130", "name": "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_5221122" ], "products": [ "species_113550", "species_5221124" ], "modifiers": [ [ "species_10744759", "catalyst" ] ], "additional_components": [ "SPAC1952.13" ] }, "reaction_10744778": { "compartment": "compartment_13231", "id": "reaction_10744778", "reactome": "R-SPO-4419948", "name": "CTDNEP1:CNEP1R1 dephosphorylates LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10744753" ], "products": [ "species_10744759", "species_113550" ], "modifiers": [ [ "species_10744775", "catalyst" ] ], "additional_components": [ "SPAC1952.13", "SPAC1952.13", "Q9USQ0", "SPBC902.03", "O59718", "SPBC3B8.10c" ] }, "reaction_10742056": { "compartment": "compartment_12045", "id": "reaction_10742056", "reactome": "R-SPO-1482962", "name": "CDP-ETA and DAG are converted to PE by CEPT1/EPT1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500603", "species_1500596" ], "products": [ "species_109395", "species_1500581" ], "modifiers": [ [ "species_10742053", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "O13901", "SPAC22A12.10" ] }, "reaction_10742027": { "compartment": "compartment_12045", "id": "reaction_10742027", "reactome": "R-SPO-1482900", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498740", "species_1524021" ], "modifiers": [ [ "species_10741849", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742073": { "compartment": "compartment_12045", "id": "reaction_10742073", "reactome": "R-SPO-1482976", "name": "CDP-DAG is converted to PI by CDIPT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426955", "species_426910" ], "products": [ "species_109395", "species_426639" ], "modifiers": [ [ "species_10742070", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "Q10153", "SPAC1D4.08" ] }, "reaction_10742110": { "compartment": "compartment_12045", "id": "reaction_10742110", "reactome": "R-SPO-1483081", "name": "PCho and CTP are condensed to CDP-Cho by PCYT1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_1524071" ], "products": [ "species_111294", "species_1524060" ], "modifiers": [ [ "species_10742107", "catalyst" ] ], "additional_components": [ "O74975", "SPCC1827.02c" ] }, "reaction_10742173": { "compartment": "compartment_70101", "id": "reaction_10742173", "reactome": "R-SPO-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1498751" ], "products": [ "species_29370", "species_428686" ], "modifiers": [ [ "species_10742170", "catalyst" ] ], "additional_components": [ "Q10276", "SPAC13G7.12c" ] }, "reaction_10749967": { "compartment": "compartment_12045", "id": "reaction_10749967", "reactome": "R-SPO-5696448", "name": "AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696449", "species_6782195" ], "products": [ "species_76194", "species_1500596" ], "modifiers": [ [ "species_10749964", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10742021": { "compartment": "compartment_12045", "id": "reaction_10742021", "reactome": "R-SPO-1482889", "name": "DAG is acylated to TAG by DGAT1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10740247", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10741961": { "compartment": "compartment_70616", "id": "reaction_10741961", "reactome": "R-SPO-1482745", "name": "PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524027" ], "modifiers": [ [ "species_10741958", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742032": { "compartment": "compartment_12045", "id": "reaction_10742032", "reactome": "R-SPO-1482920", "name": "PG is hydrolyzed to 2-acyl LPG by PLA2[14]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1483256", "species_29356" ], "products": [ "species_1498730", "species_1524021" ], "modifiers": [ [ "species_10742029", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10753720": { "compartment": "compartment_12045", "id": "reaction_10753720", "reactome": "R-SPO-8848580", "name": "DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500578", "species_1500596" ], "products": [ "species_76194", "species_1500594" ], "modifiers": [ [ "species_10753715", "catalyst" ] ], "additional_components": [ "SPCC1235.15" ] }, "reaction_10741907": { "compartment": "compartment_12045", "id": "reaction_10741907", "reactome": "R-SPO-1482685", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10749937": { "compartment": "compartment_17906", "id": "reaction_10749937", "reactome": "R-SPO-5696074", "name": "AGK:Mg2+ phosphorylates MAG, DAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696069", "species_5696066" ], "products": [ "species_5696026", "species_5696037" ], "modifiers": [ [ "species_10749934", "catalyst" ] ], "additional_components": [ "species_1500596", "species_6814795", "species_1500590", "species_417891", "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04", "species_29926" ] }, "reaction_10741782": { "compartment": "compartment_12045", "id": "reaction_10741782", "reactome": "R-SPO-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498728", "species_29356" ], "products": [ "species_76116", "species_1500593" ], "modifiers": [ [ "species_10741779", "catalyst" ] ], "additional_components": [ "O94305", "SPCC5E4.05c" ] }, "reaction_10742017": { "compartment": "compartment_12045", "id": "reaction_10742017", "reactome": "R-SPO-1482868", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[12]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742037": { "compartment": "compartment_12045", "id": "reaction_10742037", "reactome": "R-SPO-1482932", "name": "PI is hydrolyzed to 2-acyl LPI by PLA2[13]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498737", "species_1524021" ], "modifiers": [ [ "species_10742034", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741888": { "compartment": "compartment_12045", "id": "reaction_10741888", "reactome": "R-SPO-1482626", "name": "2-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498737", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10741814", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10742002": { "compartment": "compartment_70616", "id": "reaction_10742002", "reactome": "R-SPO-1482847", "name": "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_113521" ], "products": [ "species_1524085", "species_1524047" ], "modifiers": [ [ "species_10741958", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741852": { "compartment": "compartment_17906", "id": "reaction_10741852", "reactome": "R-SPO-1482604", "name": "PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590", "species_29356" ], "products": [ "species_1524103", "species_1500580" ], "modifiers": [ [ "species_10741849", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742010": { "compartment": "compartment_12045", "id": "reaction_10742010", "reactome": "R-SPO-1482861", "name": "MLCL is acylated to CL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524069", "species_1500578" ], "products": [ "species_76194", "species_1524081" ], "modifiers": [ [ "species_10733368", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10742120": { "compartment": "compartment_12045", "id": "reaction_10742120", "reactome": "R-SPO-1483121", "name": "PA is converted to CDP-DAG by CDS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_426755" ], "products": [ "species_426955", "species_111294" ], "modifiers": [ [ "species_10742117", "catalyst" ] ], "additional_components": [ "Q9P381", "SPBC13A2.03", "species_29926" ] }, "reaction_10741807": { "compartment": "compartment_70616", "id": "reaction_10741807", "reactome": "R-SPO-1482546", "name": "2-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524047", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10741804", "catalyst" ] ], "additional_components": [ "SPAC22A12.08c" ] }, "reaction_10741890": { "compartment": "compartment_12045", "id": "reaction_10741890", "reactome": "R-SPO-1482629", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10755107": { "compartment": "compartment_70101", "id": "reaction_10755107", "reactome": "R-SPO-8869241", "name": "PITPNM1,2,3 exchange PI for PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_426639" ], "products": [ "species_426658", "species_426755" ], "modifiers": [ [ "species_10755104", "catalyst" ] ], "additional_components": [ "Q7LKZ6", "SPCC1020.13c", "P87109", "SPAC20G8.02" ] }, "reaction_10742133": { "compartment": "compartment_12045", "id": "reaction_10742133", "reactome": "R-SPO-1483174", "name": "PE is methylated to PC by PEMT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_71284" ], "products": [ "species_426925", "species_71285" ], "modifiers": [ [ "species_10742130", "catalyst" ] ], "additional_components": [ "SPBC337.16" ] }, "reaction_10741817": { "compartment": "compartment_12045", "id": "reaction_10741817", "reactome": "R-SPO-1482598", "name": "1-acyl LPI is acylated to PI by MBOAT7", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498733", "species_1500578" ], "products": [ "species_76194", "species_426639" ], "modifiers": [ [ "species_10741814", "catalyst" ] ], "additional_components": [ "SPBC16A3.10" ] }, "reaction_10741910": { "compartment": "compartment_70616", "id": "reaction_10741910", "reactome": "R-SPO-1482689", "name": "1-acyl LPG is acylated to PG by CRLS1 (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524027", "species_1524038" ], "products": [ "species_1524042", "species_29374" ], "modifiers": [ [ "species_10741804", "catalyst" ] ], "additional_components": [ "SPAC22A12.08c" ] }, "reaction_10742063": { "compartment": "compartment_20699", "id": "reaction_10742063", "reactome": "R-SPO-1482973", "name": "CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524057", "species_1524060" ], "products": [ "species_109395", "species_429785" ], "modifiers": [ [ "species_10742060", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "O13901", "SPAC22A12.10" ] }, "reaction_10742015": { "compartment": "compartment_12045", "id": "reaction_10742015", "reactome": "R-SPO-1482867", "name": "DLCL is acylated to MLCL by LCLAT1 (ER)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524080", "species_1500578" ], "products": [ "species_76194", "species_1524069" ], "modifiers": [ [ "species_10733368", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10741893": { "compartment": "compartment_12045", "id": "reaction_10741893", "reactome": "R-SPO-1482635", "name": "2-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498730", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10741772", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10741885": { "compartment": "compartment_12045", "id": "reaction_10741885", "reactome": "R-SPO-1482612", "name": "2-acyl LPC is hydrolyzed to GPCho by PLA2[8]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_975614", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741882", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742091": { "compartment": "compartment_70101", "id": "reaction_10742091", "reactome": "R-SPO-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_264618" ], "products": [ "species_29370", "species_1524071" ], "modifiers": [ [ "species_10742088", "catalyst" ] ], "additional_components": [ "Q10276", "SPAC13G7.12c" ] }, "reaction_10742153": { "compartment": "compartment_12045", "id": "reaction_10742153", "reactome": "R-SPO-1483190", "name": "PETA and CTP are condensed to CDP-ETA by PCY2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_110614", "species_428686" ], "products": [ "species_111294", "species_1500603" ], "modifiers": [ [ "species_10742150", "catalyst" ] ], "additional_components": [ "Q9UTI6", "SPAC15E1.05c" ] }, "reaction_10742094": { "compartment": "compartment_70616", "id": "reaction_10742094", "reactome": "R-SPO-1483063", "name": "PG and CDP-DAG are converted to CL by CRLS1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524042", "species_1524064" ], "products": [ "species_1524067", "species_1524072" ], "modifiers": [ [ "species_10741804", "catalyst" ] ], "additional_components": [ "SPAC22A12.08c" ] }, "reaction_10741980": { "compartment": "compartment_70616", "id": "reaction_10741980", "reactome": "R-SPO-1482759", "name": "MLCL is hydrolyzed to DLCL by PLA2G4A (IM)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498773", "species_113521" ], "products": [ "species_1524085", "species_1498753" ], "modifiers": [ [ "species_10741977", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10741902": { "compartment": "compartment_70101", "id": "reaction_10741902", "reactome": "R-SPO-1482656", "name": "PA is hydrolysed to 1-acyl LPA by PLA2[1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_1500604", "species_1524021" ], "modifiers": [ [ "species_10741849", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10733396": { "compartment": "compartment_70101", "id": "reaction_10733396", "reactome": "R-SPO-75889", "name": "DHAP is converted to G3P by GPD1/GPD1L", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_75970" ], "products": [ "species_29360", "species_76114" ], "modifiers": [ [ "species_10733393", "catalyst" ] ], "additional_components": [ "Q09845", "SPAC23D3.04c", "P21696", "SPBC215.05" ] }, "reaction_10749957": { "compartment": "compartment_5460", "id": "reaction_10749957", "reactome": "R-SPO-5696415", "name": "PXLP-K278-ETNPPL tetramer hydrolyses PETA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_5696414" ], "products": [ "species_113548", "species_5693978", "species_113532" ], "modifiers": [ [ "species_10749954", "catalyst" ] ], "additional_components": [ "Q9US34", "SPAC1039.07c" ] }, "reaction_10741914": { "compartment": "compartment_12045", "id": "reaction_10741914", "reactome": "R-SPO-1482696", "name": "1-acyl LPC is hydrolyzed to GPCho by PLA2G4C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524028", "species_29356" ], "products": [ "species_1498750", "species_1524021" ], "modifiers": [ [ "species_10741796", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10750442": { "compartment": "compartment_70101", "id": "reaction_10750442", "reactome": "R-SPO-6786650", "name": "DDHD1,2 hydrolyse PA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1602448", "species_29356" ], "products": [ "species_1602447", "species_1602366" ], "modifiers": [ [ "species_10750439", "catalyst" ] ], "additional_components": [ "Q7LKZ6", "SPCC1020.13c", "P87109", "SPAC20G8.02" ] }, "reaction_10741991": { "compartment": "compartment_12045", "id": "reaction_10741991", "reactome": "R-SPO-1482825", "name": "PI is hydrolyzed to 1-acyl LPI by PLA2[11]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_29356" ], "products": [ "species_1498733", "species_1524021" ], "modifiers": [ [ "species_10741988", "catalyst" ] ], "additional_components": [ "P78854", "SPAC1A6.04c", "species_74016", "O13857", "SPCC1450.09c", "Q9UTH5", "SPCC1450.09c", "P0CU03", "SPCC1450.09c", "P0CU02", "SPCC1450.09c", "Q9Y7N6", "SPCC1450.09c" ] }, "reaction_10742143": { "compartment": "compartment_12045", "id": "reaction_10742143", "reactome": "R-SPO-1483182", "name": "PC is hydrolyzed to PA and choline by PLD1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426925", "species_29356" ], "products": [ "species_264618", "species_426755" ], "modifiers": [ [ "species_10742138", "catalyst" ] ], "additional_components": [ "SPAC2F7.16c" ] }, "reaction_10741775": { "compartment": "compartment_12045", "id": "reaction_10741775", "reactome": "R-SPO-1482539", "name": "1-acyl LPG is acylated to PG by LPGAT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1498740", "species_1500578" ], "products": [ "species_76194", "species_1483256" ], "modifiers": [ [ "species_10741772", "catalyst" ] ], "additional_components": [ "SPBC428.14" ] }, "reaction_10733373": { "compartment": "compartment_12045", "id": "reaction_10733373", "reactome": "R-SPO-75885", "name": "1-acyl LPA is acylated to PA by AGPAT (LPAAT)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500604", "species_1500578" ], "products": [ "species_76194", "species_426755" ], "modifiers": [ [ "species_10733370", "catalyst" ] ], "additional_components": [ "O94361", "SPBC428.14", "Q9US20", "SPAC1851.02" ] }, "reaction_10755689": { "compartment": "compartment_5460", "id": "reaction_10755689", "reactome": "R-SPO-8878654", "name": "ACP6 hydrolyses MYS-LPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8878649", "species_113521" ], "products": [ "species_8934414", "species_113548" ], "modifiers": [ [ "species_10755686", "catalyst" ] ], "additional_components": [ "SPBC4.06" ] }, "reaction_10742164": { "compartment": "compartment_12045", "id": "reaction_10742164", "reactome": "R-SPO-1483203", "name": "PA is dephosphorylated to DAG by LPIN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_426755" ], "products": [ "species_29372", "species_1500596" ], "modifiers": [ [ "species_10742161", "catalyst" ] ], "additional_components": [ "Q9UUJ6", "SPAC1952.13", "species_29926" ] }, "reaction_10742047": { "compartment": "compartment_12045", "id": "reaction_10742047", "reactome": "R-SPO-1482961", "name": "CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1524060", "species_1500596" ], "products": [ "species_109395", "species_426925" ], "modifiers": [ [ "species_10742044", "catalyst" ] ], "additional_components": [ "species_113527", "species_29926", "O13901", "SPAC22A12.10" ] }, "reaction_10756967": { "compartment": "compartment_70101", "id": "reaction_10756967", "reactome": "R-SPO-9018824", "name": "RHOT2 binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756963", "species_10756946" ], "products": [ "species_10756965" ], "modifiers": [], "additional_components": [ "O74805", "SPBC2D10.14c", "Q9USY7", "SPBC1706.03", "O94477", "SPCC1919.10c", "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "O74805", "SPBC2D10.14c", "Q9USY7", "SPBC1706.03", "species_29438", "O94477", "SPCC1919.10c" ] }, "reaction_10756969": { "compartment": "compartment_70101", "id": "reaction_10756969", "reactome": "R-SPO-9018826", "name": "RHOT2 hydrolyzes GTP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756946", "species_29356" ], "products": [ "species_10756948", "species_29372" ], "modifiers": [ [ "species_10756946", "catalyst" ] ], "additional_components": [ "O59781", "SPCC320.04c", "species_29438", "O59781", "SPCC320.04c", "species_29420", "O59781", "SPCC320.04c", "species_29438" ] }, "reaction_10757850": { "compartment": "compartment_876", "id": "reaction_10757850", "reactome": "R-SPO-9693111", "name": "RHOF auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10757845" ], "products": [ "species_10757847", "species_29420" ], "modifiers": [ [ "species_10757845", "catalyst" ] ], "additional_components": [ "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01" ] }, "reaction_10757896": { "compartment": "compartment_876", "id": "reaction_10757896", "reactome": "R-SPO-9693282", "name": "RHOF GAPs stimulate RHOF GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757847", "species_29356" ], "products": [ "species_29372", "species_10757845" ], "modifiers": [ [ "species_10756838", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10752557": { "compartment": "compartment_7660", "id": "reaction_10752557", "reactome": "R-SPO-6804955", "name": "ATM phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737757" ], "products": [ "species_113582", "species_10752555" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "SPCC23B6.03c" ] }, "reaction_10755684": { "compartment": "compartment_7660", "id": "reaction_10755684", "reactome": "R-SPO-8877692", "name": "PIN1 binds phosphorylated PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740775", "species_10755677" ], "products": [ "species_10755682" ], "modifiers": [], "additional_components": [ "SPCC16C4.03", "O13853", "SPAC19G12.14", "O74448", "SPCC16C4.03", "O13853", "SPAC19G12.14" ] }, "reaction_10737784": { "compartment": "compartment_7660", "id": "reaction_10737784", "reactome": "R-SPO-349455", "name": "Phosphorylation of MDM4 by ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737774" ], "products": [ "species_113582", "species_10737762" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "O74503", "SPCC285.17", "SPCC23B6.03c" ] }, "reaction_10751191": { "compartment": "compartment_70101", "id": "reaction_10751191", "reactome": "R-SPO-6793666", "name": "MDM2 translocates to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736549" ], "products": [ "species_10737757" ], "modifiers": [], "additional_components": [ "SPCC285.17", "SPCC285.17" ] }, "reaction_10752603": { "compartment": "compartment_7660", "id": "reaction_10752603", "reactome": "R-SPO-6805640", "name": "AKT phosphorylates KAT6A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10752596" ], "products": [ "species_113582", "species_10752601" ], "modifiers": [ [ "species_10736722", "catalyst" ] ], "additional_components": [ "O14240", "SPAC6F6.09", "O74736", "SPBC1709.11c", "O94446", "SPAC637.12c", "O42871", "SPAC3G9.08", "O14240", "SPAC6F6.09", "O74736", "SPBC1709.11c", "O94446", "SPAC637.12c", "O42871", "SPAC3G9.08", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10752539": { "compartment": "compartment_7660", "id": "reaction_10752539", "reactome": "R-SPO-6804724", "name": "MDM2 ubiquitinates phosphorylated MDM4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737768", "species_10729044" ], "products": [ "species_10752536" ], "modifiers": [ [ "species_10737768", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74503", "SPCC285.17", "O74503", "SPCC285.17" ] }, "reaction_10751207": { "compartment": "compartment_70101", "id": "reaction_10751207", "reactome": "R-SPO-6795290", "name": "TORC2 complex phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10751197" ], "products": [ "species_29370", "species_10751205" ], "modifiers": [ [ "species_10736612", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "O14208", "SPAC6B12.03c", "Q09743", "SPBC12C2.02c", "Q9Y7K2", "SPBC216.07c", "O74547", "SPCC777.08c", "O74184", "SPBC21B10.05c", "Q9P7Y9", "SPAPYUG7.02c" ] }, "reaction_10751220": { "compartment": "compartment_70101", "id": "reaction_10751220", "reactome": "R-SPO-6795473", "name": "PDPK1 phosphorylates SGK1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10751205" ], "products": [ "species_29370", "species_10751215" ], "modifiers": [ [ "species_10733718", "catalyst" ] ], "additional_components": [ "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c", "species_179838", "Q12701", "SPCC576.15c" ] }, "reaction_10752549": { "compartment": "compartment_7660", "id": "reaction_10752549", "reactome": "R-SPO-6804942", "name": "MDM2 homodimers auto-ubiquitinate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751317", "species_10729044" ], "products": [ "species_10752546" ], "modifiers": [ [ "species_10751317", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74503", "SPCC285.17", "O74503", "SPCC285.17" ] }, "reaction_10751189": { "compartment": "compartment_7660", "id": "reaction_10751189", "reactome": "R-SPO-6793661", "name": "(CDK1,CDK2):CCNA phosphorylates MDM2 at T218", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737757" ], "products": [ "species_113582", "species_10751172" ], "modifiers": [ [ "species_10728937", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10753231": { "compartment": "compartment_7660", "id": "reaction_10753231", "reactome": "R-SPO-6810376", "name": "ING2 binds PI5P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744714", "species_6810408" ], "products": [ "species_10753229" ], "modifiers": [], "additional_components": [ "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08", "species_422529", "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08" ] }, "reaction_10737770": { "compartment": "compartment_7660", "id": "reaction_10737770", "reactome": "R-SPO-349426", "name": "Phosphorylation of MDM4 by CHEK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10737762" ], "products": [ "species_113582", "species_10737768" ], "modifiers": [ [ "species_10729617", "catalyst" ] ], "additional_components": [ "O74503", "SPCC285.17", "O74503", "SPCC285.17", "SPAC14C4.03" ] }, "reaction_10751222": { "compartment": "compartment_70101", "id": "reaction_10751222", "reactome": "R-SPO-6795667", "name": "MDM2 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743716" ], "products": [ "species_10736545" ], "modifiers": [], "additional_components": [ "SPCC285.17", "SPCC285.17" ] }, "reaction_10752543": { "compartment": "compartment_7660", "id": "reaction_10752543", "reactome": "R-SPO-6804741", "name": "MDM2 forms homo- or heterodimers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752541", "species_10737757" ], "products": [ "species_10751319" ], "modifiers": [ [ "species_10737781", "inhibitor" ] ], "additional_components": [ "O74503", "SPCC285.17", "SPCC285.17", "O74503", "SPCC285.17", "SPCC23B6.03c" ] }, "reaction_10755680": { "compartment": "compartment_7660", "id": "reaction_10755680", "reactome": "R-SPO-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10755666" ], "products": [ "species_113582", "species_10755677" ], "modifiers": [ [ "species_10739756", "catalyst" ] ], "additional_components": [ "O13853", "SPAC19G12.14", "O13853", "SPAC19G12.14", "P10506", "SPAC1D4.13", "Q9Y884", "SPBC543.07", "P33886", "SPBC409.07c" ] }, "reaction_10751218": { "compartment": "compartment_70101", "id": "reaction_10751218", "reactome": "R-SPO-6795460", "name": "SGK1 phosphorylates MDM2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10736545", "species_113592" ], "products": [ "species_29370", "species_10736549" ], "modifiers": [ [ "species_10751215", "catalyst" ] ], "additional_components": [ "SPCC285.17", "SPCC285.17", "Q10364", "SPAC22E12.14c", "P50530", "SPAC1B9.02c" ] }, "reaction_10751262": { "compartment": "compartment_7660", "id": "reaction_10751262", "reactome": "R-SPO-6797616", "name": "CCNK:CDK12 binds RNA Pol II at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751226", "species_10751242" ], "products": [ "species_10751244" ], "modifiers": [], "additional_components": [ "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c" ] }, "reaction_10751260": { "compartment": "compartment_7660", "id": "reaction_10751260", "reactome": "R-SPO-6797606", "name": "CDK12 phosphorylates RNA Pol II CTD at DNA repair genes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10751244" ], "products": [ "species_113582", "species_10751257" ], "modifiers": [ [ "species_10751244", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O59671", "SPBC29A3.08", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c" ] }, "reaction_10751234": { "compartment": "compartment_7660", "id": "reaction_10751234", "reactome": "R-SPO-6797100", "name": "CCNK binds CDK13", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734263", "species_10751230" ], "products": [ "species_10751232" ], "modifiers": [], "additional_components": [ "SPBC32F12.06", "SPAC2F3.15", "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15" ] }, "reaction_10751228": { "compartment": "compartment_7660", "id": "reaction_10751228", "reactome": "R-SPO-6797090", "name": "CCNK binds CDK12", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734263", "species_10751224" ], "products": [ "species_10751226" ], "modifiers": [], "additional_components": [ "SPBC32F12.06", "SPAC2F3.15", "O74627", "SPBC32F12.06", "O14098", "SPAC2F3.15" ] }, "reaction_10739697": { "compartment": "compartment_5460", "id": "reaction_10739697", "reactome": "R-SPO-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29374", "species_113539", "species_113593" ], "products": [ "species_159448", "species_159450", "species_113559" ], "modifiers": [ [ "species_10739694", "catalyst" ] ], "additional_components": [ "SPCC191.02c" ] }, "reaction_10730535": { "compartment": "compartment_70101", "id": "reaction_10730535", "reactome": "R-SPO-71707", "name": "ethanol + NAD+ => acetaldehyde + NADH + H+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30203", "species_29360" ], "products": [ "species_70106", "species_73473", "species_29510" ], "modifiers": [ [ "species_10730532", "catalyst" ] ], "additional_components": [ "species_442320", "P78870", "SPCC13B11.04c", "O74540", "SPCC13B11.04c" ] }, "reaction_10730567": { "compartment": "compartment_70101", "id": "reaction_10730567", "reactome": "R-SPO-71735", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_113592", "species_29416" ], "products": [ "species_111294", "species_76577", "species_76183" ], "modifiers": [ [ "species_10730564", "catalyst" ] ], "additional_components": [ "SPCC191.02c" ] }, "reaction_10745912": { "compartment": "compartment_876", "id": "reaction_10745912", "reactome": "R-SPO-5433067", "name": "DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490235" ], "products": [ "species_266029", "species_5490250" ], "modifiers": [ [ "species_10737679", "catalyst" ] ], "additional_components": [ "CHEBI:78579", "CHEBI:78584", "CHEBI:78578", "CHEBI:78583", "O59832", "SPCC965.12", "species_442320", "O14124", "SPCC965.12" ] }, "reaction_10730490": { "compartment": "compartment_70101", "id": "reaction_10730490", "reactome": "R-SPO-71691", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29510", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_29416" ], "modifiers": [ [ "species_10730487", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10730542": { "compartment": "compartment_5460", "id": "reaction_10730542", "reactome": "R-SPO-71723", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730539", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10749939": { "compartment": "compartment_5460", "id": "reaction_10749939", "reactome": "R-SPO-5696091", "name": "ALDH1B1 tetramer oxidises CH3CHO to CH3COOH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_113526", "species_113532" ], "products": [ "species_113539", "species_29362", "species_113529" ], "modifiers": [ [ "species_10730539", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10745935": { "compartment": "compartment_984", "id": "reaction_10745935", "reactome": "R-SPO-5433072", "name": "GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5490253", "species_109276" ], "products": [ "species_210382", "species_5490235" ], "modifiers": [ [ "species_10745932", "catalyst" ] ], "additional_components": [ "CHEBI:78587", "CHEBI:78581", "CHEBI:78579", "CHEBI:78584", "O14194", "SPAC56E4.06c", "Q9US04", "SPAC664.09" ] }, "reaction_10749510": { "compartment": "compartment_70101", "id": "reaction_10749510", "reactome": "R-SPO-5692237", "name": "ADH5 oxidises S-HMGSH to S-FGSH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5692221", "species_29360" ], "products": [ "species_73473", "species_70106", "species_5692249" ], "modifiers": [ [ "species_10749507", "catalyst" ] ], "additional_components": [ "species_442320", "O74540", "SPCC13B11.04c" ] }, "reaction_10747760": { "compartment": "compartment_12045", "id": "reaction_10747760", "reactome": "R-SPO-5689000", "name": "AADAC deacetylates PHEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5689006", "species_29356" ], "products": [ "species_5688995", "species_5689001" ], "modifiers": [ [ "species_10747757", "catalyst" ] ], "additional_components": [ "Q9US38", "SPAPB1A11.02", "Q9HDX3", "SPAPB1A11.02" ] }, "reaction_10734961": { "compartment": "compartment_5460", "id": "reaction_10734961", "reactome": "R-SPO-163310", "name": "TFAM binds to mitochondrial promoters", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_163305", "species_10734957" ], "products": [ "species_10734959" ], "modifiers": [], "additional_components": [ "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c", "Q9USU7", "SPBC28F2.11", "Q10241", "SPAC4G9.11c", "P87057", "SPAC57A10.09c" ] }, "reaction_10743032": { "compartment": "compartment_7660", "id": "reaction_10743032", "reactome": "R-SPO-2172678", "name": "PHF8 demethylates histone H4K20me1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_10743025", "species_113685" ], "products": [ "species_159942", "species_159939", "species_29478", "species_10743029" ], "modifiers": [ [ "species_10743025", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "species_113531", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "O94603", "SPCC622.16c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "species_113531", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "O94603", "SPCC622.16c", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "species_113531", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "O94603", "SPCC622.16c" ] }, "reaction_10758000": { "compartment": "compartment_12045", "id": "reaction_10758000", "reactome": "R-SPO-9714361", "name": "RHOC activates endoplasmic reticulum effectors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757996", "species_10757971" ], "products": [ "species_10757998" ], "modifiers": [], "additional_components": [ "O13644", "SPBC8D2.14c", "O42707", "SPCC126.08c", "Q09195", "SPBC16G5.18", "Q10484", "SPAC17C9.12", "O94401", "SPCC126.08c", "O60119", "SPBC16G5.05c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "O13644", "SPBC8D2.14c", "Q9HE04", "SPAC20H4.11c", "O42707", "SPCC126.08c", "Q09195", "SPBC16G5.18", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q10484", "SPAC17C9.12", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O94401", "SPCC126.08c", "species_29438", "O60119", "SPBC16G5.05c" ] }, "reaction_10758002": { "compartment": "compartment_876", "id": "reaction_10758002", "reactome": "R-SPO-9714363", "name": "RHOC translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746673" ], "products": [ "species_10757971" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10756748": { "compartment": "compartment_876", "id": "reaction_10756748", "reactome": "R-SPO-9013111", "name": "RHOC GAPs stimulate RHOC GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746673", "species_29356" ], "products": [ "species_10756724", "species_29372" ], "modifiers": [ [ "species_10756508", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10756740": { "compartment": "compartment_70101", "id": "reaction_10756740", "reactome": "R-SPO-9013108", "name": "GDIs block activation of RHOC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756724", "species_10756674" ], "products": [ "species_10756738" ], "modifiers": [], "additional_components": [ "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "SPAC6F12.06", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O14224", "SPAC6F12.06" ] }, "reaction_10756746": { "compartment": "compartment_876", "id": "reaction_10756746", "reactome": "R-SPO-9013110", "name": "RHOC binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746673", "species_10756742" ], "products": [ "species_10756744" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q10201", "SPBC17D1.07c", "P36583", "SPBC12D12.04c", "Q09914", "SPAC1F7.04", "P78953", "SPCC4B3.15", "Q92356", "SPAC6G9.11", "O14188", "SPAC4F8.13c", "O43027", "SPBC354.13", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "O43027", "SPBC354.13", "Q10133", "SPAC16.01", "species_29438", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "Q9HE04", "SPAC20H4.11c", "P36583", "SPBC12D12.04c", "O13928", "SPAC23C4.08", "O14188", "SPAC4F8.13c", "Q874R1", "SPAC16A10.04", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c" ] }, "reaction_10736357": { "compartment": "compartment_70101", "id": "reaction_10736357", "reactome": "R-SPO-196060", "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_196095" ], "products": [ "species_29366", "species_196066" ], "modifiers": [ [ "species_10736354", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10744363": { "compartment": "compartment_7660", "id": "reaction_10744363", "reactome": "R-SPO-3662318", "name": "Type B histone acetlytransferase complex acetylates histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732874", "species_113560" ], "products": [ "species_2485002", "species_10744336" ], "modifiers": [ [ "species_10744360", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "Q9Y825", "SPAC25H1.06", "O14021", "SPAC29A4.18", "Q9UTM7", "SPAC139.06", "O94244", "SPCC1672.10" ] }, "reaction_10744059": { "compartment": "compartment_7660", "id": "reaction_10744059", "reactome": "R-SPO-3318415", "name": "ATF2 acetylates histone H2B, H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744046", "species_113560" ], "products": [ "species_2485002", "species_10744056" ], "modifiers": [ [ "species_10735245", "catalyst" ] ], "additional_components": [ "P09322", "SPAC1834.03c", "P04913", "SPCC622.09", "P09322", "SPAC1834.03c", "P04913", "SPCC622.09", "P52890", "SPBC29B5.01", "P78962", "SPBC2F12.09c", "Q09771", "SPAC22F3.02" ] }, "reaction_10756972": { "compartment": "compartment_70101", "id": "reaction_10756972", "reactome": "R-SPO-9018862", "name": "LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_9022655" ], "products": [ "species_9022660" ], "modifiers": [ [ "species_10737736", "catalyst" ] ], "additional_components": [ "species_442320", "O94544", "SPCC1322.05c" ] }, "reaction_10742548": { "compartment": "compartment_70101", "id": "reaction_10742548", "reactome": "R-SPO-1799332", "name": "Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742542", "species_10742544" ], "products": [ "species_10742546" ], "modifiers": [], "additional_components": [ "P21565", "SPCC188.06c", "O74436", "SPCC1682.05c", "O59787", "SPCC320.10", "O13804", "SPAC17H9.07", "O94407", "SPCC126.15c", "Q9P372", "SPAC19B12.09", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", 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"Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740756" ], "products": [ "species_10733183", "species_10740705", "species_10734667", "species_10740725", "species_10740717", "species_10731799", "species_10740723", "species_10740674" ], "modifiers": [ [ "species_10740705", "catalyst" ], [ "species_10740752", "catalyst" ] ], "additional_components": [ "Q9P6M8", "SPAC1610.03c", "Q10475", "SPAC17C9.03", "P31209", "SPAC57A7.04c", "Q09820", "SPAC16C9.06c", "O14338", "SPBC2F12.03c", "Q9UT08", "SPAP8A3.09c", "Q9P383", "SPBC13A2.01c", "P23636", "SPBC16H5.07c", "O14253", "SPAC6G10.07", "O74804", "SPBC2D10.13", "Q12702", "SPAC57A7.04c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "Q9P6M8", "SPAC1610.03c", "P31209", "SPAC57A7.04c", "SPBC2D10.13", "O14338", "SPBC2F12.03c", "O74804", "SPBC2D10.13", "SPAC17C9.03", "O14338", "SPBC2F12.03c", "O74804", "SPBC2D10.13", "SPAC16C9.06c", "Q9UT08", "SPAP8A3.09c", "P23636", "SPBC16H5.07c", "Q12702", "SPAC57A7.04c", "SPAC16C9.06c" ] }, "reaction_10740770": { "compartment": "compartment_70101", "id": "reaction_10740770", "reactome": "R-SPO-927889", "name": "SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740767", "species_113592" ], "products": [ "species_29370", "species_10740754" ], "modifiers": [ [ "species_10740767", "catalyst" ] ], "additional_components": [ "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", 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"SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "O43037", "SPBC3B9.08c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "Q10267", "SPAC13G7.03", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "Q1MTR2", "SPBC13G1.14c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07" ] }, "reaction_10740765": { "compartment": "compartment_70101", "id": "reaction_10740765", "reactome": "R-SPO-927836", "name": "SMG6 hydrolyzes mRNA with premature termination codon", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740762" ], "products": [ "species_10740756" ], "modifiers": [ [ "species_10740762", "catalyst" ] ], "additional_components": [ "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "Q12702", "SPAC57A7.04c", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "Q9UT08", "SPAP8A3.09c", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", 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"Q09757", "SPAC24H6.07", "Q10055", "SPAC1F5.10", "P05764", "SPBC18E5.06", "O42699", "SPCC1682.14", "O13824", "SPAC19A8.08", "P0CT83", "SPCC16C4.13c", "Q9P4W9", "SPAC959.07", "P23636", "SPBC16H5.07c", "Q9US22", "SPAC1783.08c", "O74172", "SPBC3D6.15", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "Q9P546", "SPAPJ698.02c", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "O43037", "SPBC3B9.08c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "Q10267", "SPAC13G7.03", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "O74804", "SPBC2D10.13", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "O14338", "SPBC2F12.03c", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "Q1MTR2", "SPBC13G1.14c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07" ] }, "reaction_10755910": { "compartment": "compartment_876", "id": "reaction_10755910", "reactome": "R-SPO-8941234", "name": "SH3PXD2A binds ADAM12,ADAM15,ADAM19", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755902", "species_10755900" ], "products": [ "species_10755908" ], "modifiers": [], "additional_components": [ "SPAC17A5.04c", "species_202247", "P40996", "SPAC22H10.07", "species_202247", "P40996", "SPAC22H10.07", "O13766", "SPAC17A5.04c" ] }, "reaction_10740377": { "compartment": "compartment_70101", "id": "reaction_10740377", "reactome": "R-SPO-893596", "name": "PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29398", "species_29970" ], "products": [ "species_893615", "species_29432" ], "modifiers": [ [ "species_10740371", "catalyst" ], [ "species_8939576", "inhibitor" ], [ "species_29502", "inhibitor" ] ], "additional_components": [ "O14209", "SPAC6B12.04c", "CHEBI:55528", "CHEBI:43580" ] }, "reaction_10749439": { "compartment": "compartment_70101", "id": "reaction_10749439", "reactome": "R-SPO-5690319", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10749434" ], "products": [ "species_1131871", "species_10749436" ], "modifiers": [ [ "species_10749434", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10171", "SPAC27F1.03c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10171", "SPAC27F1.03c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q10171", "SPAC27F1.03c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10744634": { "compartment": "compartment_7660", "id": "reaction_10744634", "reactome": "R-SPO-3968362", "name": "SUMOylation of PIAS4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10743707" ], "products": [ "species_10743639", "species_10744632" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC1687.05", "SPAC30D11.13", "O13351", "SPBC365.06", "O94451", "SPAC1687.05", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750477": { "compartment": "compartment_12045", "id": "reaction_10750477", "reactome": "R-SPO-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788753", "species_71284" ], "products": [ "species_6788758", "species_71285" ], "modifiers": [ [ "species_10750474", "catalyst" ] ], "additional_components": [ "species_442320", "P87014", "SPAC10F6.12c" ] }, "reaction_10734835": { "compartment": "compartment_70101", "id": "reaction_10734835", "reactome": "R-SPO-162730", "name": "phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426639", "species_162756" ], "products": [ "species_110096", "species_8855657" ], "modifiers": [ [ "species_10734832", "catalyst" ] ], "additional_components": [ "O59802", "SPCC550.04c", "Q9USW6", "SPBC21B10.11", "P87172", "SPBC3D6.07", "Q9Y7L7", "SPBC685.05", "O13904", "SPAC22A12.13", "O14357", "SPBC30D10.11" ] }, "reaction_10744958": { "compartment": "compartment_7660", "id": "reaction_10744958", "reactome": "R-SPO-4615873", "name": "PIAS2-2 SUMOylates SUZ12 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744943" ], "products": [ "species_10743639", "species_10744956" ], "modifiers": [ [ "species_10743728", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O94522", "SPCC1281.05", "O74792", "SPBC26H8.09c", "SPAC30D11.13", "O13351", "SPBC365.06", "O94522", "SPCC1281.05", "O74792", "SPBC26H8.09c", "SPAC1687.05" ] }, "reaction_10745032": { "compartment": "compartment_7660", "id": "reaction_10745032", "reactome": "R-SPO-4641362", "name": "SUMOylation of TOP1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10745022" ], "products": [ "species_10745030", "species_10743639" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC1703.14c", "P07799", "SPBC1703.14c", "O13351", "SPBC365.06", "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10739546": { "compartment": "compartment_17957", "id": "reaction_10739546", "reactome": "R-SPO-446202", "name": "Addition of the first glucose to the N-glycan precursor by ALG6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449371", "species_532542" ], "products": [ "species_449311", "species_449649" ], "modifiers": [ [ "species_10739543", "catalyst" ] ], "additional_components": [ "SPBC342.01c" ] }, "reaction_10740200": { "compartment": "compartment_70101", "id": "reaction_10740200", "reactome": "R-SPO-532549", "name": "MPI isomerises Fru6P to Man6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29512" ], "products": [ "species_532562" ], "modifiers": [ [ "species_10740197", "catalyst" ] ], "additional_components": [ "SPBC2G2.16" ] }, "reaction_10734722": { "compartment": "compartment_70101", "id": "reaction_10734722", "reactome": "R-SPO-156910", "name": "Formation of eEF1B complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734718", "species_10734713", "species_10734711" ], "products": [ "species_10734720" ], "modifiers": [], "additional_components": [ "SPAC29A4.02c", "SPCC1450.04", "SPCC1450.04", "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04" ] }, "reaction_10755736": { "compartment": "compartment_70101", "id": "reaction_10755736", "reactome": "R-SPO-8879123", "name": "PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10731529", "species_71284" ], "products": [ "species_71285", "species_10755728" ], "modifiers": [ [ "species_10755733", "catalyst" ] ], "additional_components": [ "SPCC576.08c", "SPCC576.08c", "SPBC8D2.10c" ] }, "reaction_10744624": { "compartment": "compartment_7660", "id": "reaction_10744624", "reactome": "R-SPO-3900177", "name": "SUMOylation of DDX5 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10730920" ], "products": [ "species_10743639", "species_10744622" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBP8B7.16c", "SPAC30D11.13", "O13351", "SPBC365.06", "P24782", "SPBP8B7.16c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750113": { "compartment": "compartment_70101", "id": "reaction_10750113", "reactome": "R-SPO-6781797", "name": "USP19 binds HIF1A,BIRC2,BIRC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737150", "species_10750109" ], "products": [ "species_10750111" ], "modifiers": [], "additional_components": [ "SPCC962.02c", "SPBC18H10.08c", "O60139", "SPBC18H10.08c", "O14064", "SPCC962.02c" ] }, "reaction_10744889": { "compartment": "compartment_7660", "id": "reaction_10744889", "reactome": "R-SPO-4570496", "name": "SUMOylation of Histone H4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732874", "species_10743647" ], "products": [ "species_10743639", "species_10744887" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "P09322", "SPAC1834.03c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750212": { "compartment": "compartment_70101", "id": "reaction_10750212", "reactome": "R-SPO-6781953", "name": "YOD1 binds VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745608", "species_10750208" ], "products": [ "species_10750210" ], "modifiers": [], "additional_components": [ "SPAC1565.08", "SPAC24C9.14", "O13974", "SPAC24C9.14", "Q9P3A7", "SPAC1565.08" ] }, "reaction_10737483": { "compartment": "compartment_70101", "id": "reaction_10737483", "reactome": "R-SPO-204617", "name": "DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_204628", "species_10737463" ], "products": [ "species_29360", "species_204635", "species_10737473" ], "modifiers": [ [ "species_10737480", "catalyst" ] ], "additional_components": [ "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "O94337", "SPBC1271.04c" ] }, "reaction_10746712": { "compartment": "compartment_70101", "id": "reaction_10746712", "reactome": "R-SPO-5665871", "name": "ADRM1 binds 26S proteasome", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729366", "species_10746683" ], "products": [ "species_10746685" ], "modifiers": [], "additional_components": [ "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13", "SPBC342.04", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10755788": { "compartment": "compartment_70101", "id": "reaction_10755788", "reactome": "R-SPO-8932276", "name": "VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745608", "species_71284" ], "products": [ "species_71285", "species_10755776" ], "modifiers": [ [ "species_10755785", "catalyst" ] ], "additional_components": [ "SPAC1565.08", "SPAC1565.08", "O13926", "SPAC23C4.06c", "P87241", "SPCC4G3.16" ] }, "reaction_10750092": { "compartment": "compartment_7660", "id": "reaction_10750092", "reactome": "R-SPO-5697009", "name": "USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10750085" ], "products": [ "species_10750089", "species_10748683" ], "modifiers": [ [ "species_10750085", "catalyst" ] ], "additional_components": [ "P41836", "SPBC23G7.12c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "Q9C0X6", "SPAPB8E5.09", "P25009", "SPBC19F5.01c", "Q9P7V9", "SPBC1703.12", "P41836", "SPBC23G7.12c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "Q9C0X6", "SPAPB8E5.09", "P25009", "SPBC19F5.01c", "Q9P7V9", "SPBC1703.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P41836", "SPBC23G7.12c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "Q9C0X6", "SPAPB8E5.09", "P25009", "SPBC19F5.01c", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10746689": { "compartment": "compartment_70101", "id": "reaction_10746689", "reactome": "R-SPO-5665854", "name": "ADRM1:26S proteaseome binds UCHL5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746685", "species_10746678" ], "products": [ "species_10746687" ], "modifiers": [], "additional_components": [ "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13", "SPBC409.06", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "Q9UUB6", "SPBC409.06", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10734866": { "compartment": "compartment_12045", "id": "reaction_10734866", "reactome": "R-SPO-162798", "name": "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500581", "species_8855659" ], "products": [ "species_8855663", "species_1500596" ], "modifiers": [ [ "species_10734863", "catalyst" ] ], "additional_components": [ "SPBC839.08c" ] }, "reaction_10744744": { "compartment": "compartment_7660", "id": "reaction_10744744", "reactome": "R-SPO-4090284", "name": "SUMOylation of HIPK2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744734", "species_10743647" ], "products": [ "species_10743639", "species_10744742" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC823.03", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "Q9P6P3", "SPAC823.03", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10745739": { "compartment": "compartment_70101", "id": "reaction_10745739", "reactome": "R-SPO-5358494", "name": "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745719", "species_71284" ], "products": [ "species_10745706", "species_353106" ], "modifiers": [ [ "species_10745736", "catalyst" ] ], "additional_components": [ "SPAC513.01c", "SPAC513.01c", "Q10206", "SPBC17D1.02", "Q9UT33", "SPAC8F11.02c", "O59713", "SPBC3B8.05" ] }, "reaction_10739520": { "compartment": "compartment_17957", "id": "reaction_10739520", "reactome": "R-SPO-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449312", "species_449229" ], "products": [ "species_449311", "species_449365" ], "modifiers": [ [ "species_10739517", "catalyst" ] ], "additional_components": [ "SPBC1734.12c" ] }, "reaction_10739488": { "compartment": "compartment_17957", "id": "reaction_10739488", "reactome": "R-SPO-446188", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449298", "species_449229" ], "products": [ "species_449311", "species_449315" ], "modifiers": [ [ "species_10739485", "catalyst" ] ], "additional_components": [ "SPAC7D4.06c" ] }, "reaction_10734874": { "compartment": "compartment_12045", "id": "reaction_10734874", "reactome": "R-SPO-162821", "name": "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855667", "species_449229" ], "products": [ "species_8855656", "species_162872" ], "modifiers": [ [ "species_10734871", "catalyst" ] ], "additional_components": [ "SPCC16A11.06c" ] }, "reaction_10750032": { "compartment": "compartment_7660", "id": "reaction_10750032", "reactome": "R-SPO-5696605", "name": "USP12, USP26 deubiquitinate AR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750027", "species_113518" ], "products": [ "species_10750029", "species_10748683" ], "modifiers": [ [ "species_10750027", "catalyst" ] ], "additional_components": [ "Q10437", "SPAC12B10.03", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "Q10437", "SPAC12B10.03", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q10437", "SPAC12B10.03", "Q09731", "SPAC31A2.14", "Q9P7V9", "SPBC1703.12" ] }, "reaction_10745006": { "compartment": "compartment_7660", "id": "reaction_10745006", "reactome": "R-SPO-4641342", "name": "SUMOylation of TOP2A with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744996", "species_10743647" ], "products": [ "species_10743639", "species_10745004" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPBC1A4.03c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "P08096", "SPBC1A4.03c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10737507": { "compartment": "compartment_70101", "id": "reaction_10737507", "reactome": "R-SPO-204662", "name": "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_73473", "species_10737463", "species_29368" ], "products": [ "species_29360", "species_10737497", "species_29356" ], "modifiers": [ [ "species_10737504", "catalyst" ] ], "additional_components": [ "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "Q9UST4", "SPBC336.10c", "P56289", "SPAC26H5.10c", "Q9P6K9", "SPAC30C2.02", "species_113531" ] }, "reaction_10744694": { "compartment": "compartment_7660", "id": "reaction_10744694", "reactome": "R-SPO-4085350", "name": "SUMOylation of UBE2I with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743639", "species_10743647" ], "products": [ "species_10743639", "species_10744692" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10750295": { "compartment": "compartment_7660", "id": "reaction_10750295", "reactome": "R-SPO-6782820", "name": "USP17 deubiquitinates SUDS3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10750290" ], "products": [ "species_10750292", "species_10748291" ], "modifiers": [ [ "species_10750290", "catalyst" ] ], "additional_components": [ "O74442", "SPCC1682.12c", "Q9P7M1", "SPBC21C3.02c", "O74442", "SPCC1682.12c", "Q9P7M1", "SPBC21C3.02c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74442", "SPCC1682.12c", "Q9P7M1", "SPBC21C3.02c" ] }, "reaction_10734882": { "compartment": "compartment_70101", "id": "reaction_10734882", "reactome": "R-SPO-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855657", "species_29356" ], "products": [ "species_29416", "species_8855661" ], "modifiers": [ [ "species_10734879", "catalyst" ] ], "additional_components": [ "SPAPB2B4.01c" ] }, "reaction_10748686": { "compartment": "compartment_7660", "id": "reaction_10748686", "reactome": "R-SPO-5689950", "name": "USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10747837" ], "products": [ "species_10748683", "species_10747843" ], "modifiers": [ [ "species_10747837", "catalyst" ] ], "additional_components": [ "Q09879", "SPCC188.08c", "O74503", "SPCC285.17", "O94526", "SPBC609.02", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q09879", "SPCC188.08c", "O74503", "SPCC285.17", "O94526", "SPBC609.02", "Q09879", "SPCC188.08c", "O74503", "SPCC285.17", "O94526", "SPBC609.02" ] }, "reaction_10734803": { "compartment": "compartment_12045", "id": "reaction_10734803", "reactome": "R-SPO-162721", "name": "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449299" ], "products": [ "species_162681", "species_29420" ], "modifiers": [ [ "species_10734800", "catalyst" ] ], "additional_components": [ "O94633", "SPBC1677.02", "Q9USW6", "SPBC21B10.11", "O14466", "SPAC31G5.16c" ] }, "reaction_10752208": { "compartment": "compartment_70101", "id": "reaction_10752208", "reactome": "R-SPO-6800138", "name": "N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284", "species_10752186" ], "products": [ "species_10752193", "species_71285" ], "modifiers": [ [ "species_10752205", "catalyst" ] ], "additional_components": [ "O74718", "SPCC584.04", "P79063", "SPAC1834.01", "species_29438", "O74718", "SPCC584.04", "P79063", "SPAC1834.01", "species_29438", "Q9UT94", "SPAC323.05c", "Q09723", "SPAC31A2.02" ] }, "reaction_10744991": { "compartment": "compartment_7660", "id": "reaction_10744991", "reactome": "R-SPO-4616015", "name": "SUMOylation of HDAC2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744524" ], "products": [ "species_10743639", "species_10744989" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC36.05c", "SPAC30D11.13", "O59702", "SPBC36.05c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744684": { "compartment": "compartment_7660", "id": "reaction_10744684", "reactome": "R-SPO-4085331", "name": "PIAS2-1 SUMOylates PARK7 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744673" ], "products": [ "species_10743639", "species_10744681" ], "modifiers": [ [ "species_10743728", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC22E12.03c", "SPAC30D11.13", "O13351", "SPBC365.06", "Q10356", "SPAC22E12.03c", "SPAC1687.05" ] }, "reaction_10750010": { "compartment": "compartment_70101", "id": "reaction_10750010", "reactome": "R-SPO-5696600", "name": "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750001", "species_29356" ], "products": [ "species_10749260", "species_10750007" ], "modifiers": [ [ "species_10750001", "catalyst" ] ], "additional_components": [ "O94448", "SPAC1687.02", "O74442", "SPCC1682.12c", "P06652", "SPAC24H6.05", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O94448", "SPAC1687.02", "O74442", "SPCC1682.12c", "P06652", "SPAC24H6.05", "O94448", "SPAC1687.02", "O74442", "SPCC1682.12c", "P06652", "SPAC24H6.05" ] }, "reaction_10734890": { "compartment": "compartment_12045", "id": "reaction_10734890", "reactome": "R-SPO-162873", "name": "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855663", "species_449229" ], "products": [ "species_162872", "species_8855667" ], "modifiers": [ [ "species_10734887", "catalyst" ] ], "additional_components": [ "SPAC18B11.05" ] }, "reaction_10739496": { "compartment": "compartment_17957", "id": "reaction_10739496", "reactome": "R-SPO-446189", "name": "Addition of a second glucose to the N-glycan precursor by ALG8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449649", "species_532542" ], "products": [ "species_449311", "species_449638" ], "modifiers": [ [ "species_10739493", "catalyst" ] ], "additional_components": [ "SPAC17C9.07" ] }, "reaction_10739692": { "compartment": "compartment_70101", "id": "reaction_10739692", "reactome": "R-SPO-449734", "name": "Acetylation of glucosamine 6-phosphate to GlcNAc6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449701", "species_76183" ], "products": [ "species_76194", "species_449703" ], "modifiers": [ [ "species_10739689", "catalyst" ] ], "additional_components": [ "O13738", "SPAC16E8.03" ] }, "reaction_10734739": { "compartment": "compartment_70101", "id": "reaction_10734739", "reactome": "R-SPO-156930", "name": "GTP-binding activates eEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10734735" ], "products": [ "species_10734737" ], "modifiers": [], "additional_components": [ "SPAC513.01c", "O14460", "SPAC513.01c", "species_29438" ] }, "reaction_10734850": { "compartment": "compartment_12045", "id": "reaction_10734850", "reactome": "R-SPO-162742", "name": "(ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855660" ], "products": [ "species_8855660" ], "modifiers": [ [ "species_10734847", "catalyst" ] ], "additional_components": [ "Q09782", "SPAC13G6.03", "Q9Y7P2", "SPCC1450.15" ] }, "reaction_10755240": { "compartment": "compartment_70101", "id": "reaction_10755240", "reactome": "R-SPO-8870466", "name": "RGGT:CHM binds RABs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755236", "species_10755140" ], "products": [ "species_10755238" ], "modifiers": [], "additional_components": [ "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "Q9HDY0", "SPAPB1A10.10c", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O94412", "SPCC1620.05", "species_1131164", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03", "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "O94412", "SPCC1620.05", "Q9HDY0", "SPAPB1A10.10c", "species_1131164", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P46960", "SPAC167.02", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03" ] }, "reaction_10755404": { "compartment": "compartment_70101", "id": "reaction_10755404", "reactome": "R-SPO-8870469", "name": "RGGT geranylgeranylates RAB proteins", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755238", "species_1131164" ], "products": [ "species_111294", "species_10755401", "species_10755399" ], "modifiers": [ [ "species_10755238", "catalyst" ] ], "additional_components": [ "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "O94412", "SPCC1620.05", "Q9HDY0", "SPAPB1A10.10c", "species_1131164", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P46960", "SPAC167.02", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03", "O94412", "SPCC1620.05", "species_1131164", "P46960", "SPAC167.02", "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "Q9HDY0", "SPAPB1A10.10c", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03", "species_29420", "O94655", "SPBC405.04c", "P17610", "SPAC18G6.03", "O94412", "SPCC1620.05", "Q9HDY0", "SPAPB1A10.10c", "species_1131164", "P17609", "SPAC9E9.07c", "P11620", "SPBC1703.10", "P46960", "SPAC167.02", "P17608", "SPAC4C5.02c", "O13876", "SPAC1B3.11c", "O60112", "SPBC15C4.03" ] }, "reaction_10755807": { "compartment": "compartment_70101", "id": "reaction_10755807", "reactome": "R-SPO-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734704", "species_71284" ], "products": [ "species_71285", "species_10755799" ], "modifiers": [ [ "species_10755804", "catalyst" ] ], "additional_components": [ "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "SPBC839.14c" ] }, "reaction_10739597": { "compartment": "compartment_17957", "id": "reaction_10739597", "reactome": "R-SPO-446216", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449229", "species_449365" ], "products": [ "species_449311", "species_449371" ], "modifiers": [ [ "species_10739592", "catalyst" ] ], "additional_components": [ "SPAC1834.05" ] }, "reaction_10734683": { "compartment": "compartment_70101", "id": "reaction_10734683", "reactome": "R-SPO-156823", "name": "Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734669", "species_10734679" ], "products": [ "species_10734681" ], "modifiers": [], "additional_components": [ "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "O42848", "SPAC23A1.11", "O42991", "SPBC839.13c", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "O94513", "SPBC646.09c", "Q09130", "SPBC17G9.09", "P0CT74", "SPAC144.11", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "O43060", "SPBC4C3.07", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O42848", "SPAC23A1.11", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O14369", "SPBC18H10.04c", "Q10475", "SPAC17C9.03", "P47943", "SPAC1006.07", "P0CT59", "SPAC5D6.01", "Q9UT48", "SPAC821.05", "P56329", "SPAC32A11.04c", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q10425", "SPAC25G10.08", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O94236", "SPAC637.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "P56286", "SPAC3G9.09c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "O74743", "SPBC1709.18", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "O74760", "SPBC17D11.05", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "O42991", "SPBC839.13c", "O14164", "SPAC4A8.16c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "P87128", "SPAC3A12.13c", "species_29438", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "P55877", "SPBC25H2.07", "Q09722", "SPAC1751.03", "P79083", "SPAC4D7.05", "Q9UTQ6", "SPAC1071.07c", "P78795", "SPBC18H10.03", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15" ] }, "reaction_10739605": { "compartment": "compartment_12045", "id": "reaction_10739605", "reactome": "R-SPO-446218", "name": "Addition of the first mannose to the N-glycan precursor by ALG1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449293" ], "products": [ "species_449283", "species_29420" ], "modifiers": [ [ "species_10739602", "catalyst" ] ], "additional_components": [ "SPAC23C4.14" ] }, "reaction_10739504": { "compartment": "compartment_12045", "id": "reaction_10739504", "reactome": "R-SPO-446191", "name": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449299", "species_162756" ], "products": [ "species_109402", "species_449222" ], "modifiers": [ [ "species_10739501", "catalyst" ] ], "additional_components": [ "SPBC15D4.04" ] }, "reaction_10739556": { "compartment": "compartment_70101", "id": "reaction_10739556", "reactome": "R-SPO-446204", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532204", "species_29494" ], "products": [ "species_111294", "species_162756" ], "modifiers": [ [ "species_10739553", "catalyst" ] ], "additional_components": [ "O94617", "SPBC1289.08" ] }, "reaction_10739571": { "compartment": "compartment_12045", "id": "reaction_10739571", "reactome": "R-SPO-446207", "name": "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449222", "species_162756" ], "products": [ "species_449293", "species_110096" ], "modifiers": [ [ "species_10739568", "catalyst" ] ], "additional_components": [ "O14190", "SPAC56E4.02c", "O14199", "SPAC5D6.06c" ] }, "reaction_10755142": { "compartment": "compartment_70101", "id": "reaction_10755142", "reactome": "R-SPO-8870465", "name": "RGGT binds the RAB-binding subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755132", "species_10755138", "species_1131164" ], "products": [ "species_10755140" ], "modifiers": [], "additional_components": [ "O94412", "SPCC1620.05", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03", "O94412", "SPCC1620.05", "species_1131164", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03" ] }, "reaction_10734858": { "compartment": "compartment_12045", "id": "reaction_10734858", "reactome": "R-SPO-162797", "name": "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8855656", "species_449229" ], "products": [ "species_8855664" ], "modifiers": [ [ "species_10734855", "catalyst" ] ], "additional_components": [ "SPAC4G8.12c" ] }, "reaction_10744931": { "compartment": "compartment_7660", "id": "reaction_10744931", "reactome": "R-SPO-4615872", "name": "RANBP2 SUMOylates HDAC4 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744921" ], "products": [ "species_10743639", "species_10744929" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC800.03", "SPAC30D11.13", "O13351", "SPBC365.06", "P56523", "SPBC800.03", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10739538": { "compartment": "compartment_70101", "id": "reaction_10739538", "reactome": "R-SPO-446201", "name": "PMM1,2 isomerise Man6P to Man1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_532562" ], "products": [ "species_532531" ], "modifiers": [ [ "species_10739533", "catalyst" ] ], "additional_components": [ "SPAC1556.07" ] }, "reaction_10744981": { "compartment": "compartment_7660", "id": "reaction_10744981", "reactome": "R-SPO-4615910", "name": "SUMOylation of PCNA with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729457", "species_10743647" ], "products": [ "species_10743639", "species_10744979" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "SPBC16D10.09", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "Q03392", "SPBC16D10.09", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10744729": { "compartment": "compartment_7660", "id": "reaction_10744729", "reactome": "R-SPO-4086083", "name": "SUMOylation of ING2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744714", "species_10743647" ], "products": [ "species_10743639", "species_10744727" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPAC30D11.13", "O13351", "SPBC365.06", "O74736", "SPBC1709.11c", "O42871", "SPAC3G9.08", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10748783": { "compartment": "compartment_7660", "id": "reaction_10748783", "reactome": "R-SPO-5690080", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10748776" ], "products": [ "species_10729044", "species_10748780" ], "modifiers": [ [ "species_10748776", "catalyst" ] ], "additional_components": [ "O74443", "SPCC1682.13", "Q9P7J7", "SPCC24B10.08c", "P04910", "SPAC19G12.06c", "O13719", "SPAC14C4.12c", "P04913", "SPCC622.09", "O60171", "SPBC21H7.02", "Q9UUK2", "SPAC1952.05", "Q09869", "SPAC12G12.05c", "Q9UUD6", "SPBC19C2.04c", "P04909", "SPCC622.08c", "Q9USU8", "SPBC28F2.10c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "O74443", "SPCC1682.13", "Q9P7J7", "SPCC24B10.08c", "P04910", "SPAC19G12.06c", "O13719", "SPAC14C4.12c", "P04913", "SPCC622.09", "O60171", "SPBC21H7.02", "Q9UUK2", "SPAC1952.05", "Q09869", "SPAC12G12.05c", "Q9UUD6", "SPBC19C2.04c", "P04909", "SPCC622.08c", "Q9USU8", "SPBC28F2.10c", "O74443", "SPCC1682.13", "Q9P7J7", "SPCC24B10.08c", "P04910", "SPAC19G12.06c", "O13719", "SPAC14C4.12c", "P04913", "SPCC622.09", "O60171", "SPBC21H7.02", "Q9UUK2", "SPAC1952.05", "Q09869", "SPAC12G12.05c", "Q9UUD6", "SPBC19C2.04c", "P04909", "SPCC622.08c", "Q9USU8", "SPBC28F2.10c" ] }, "reaction_10747105": { "compartment": "compartment_70101", "id": "reaction_10747105", "reactome": "R-SPO-5676966", "name": "PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5687536", "species_71284" ], "products": [ "species_71285", "species_5687529" ], "modifiers": [ [ "species_10747102", "catalyst" ] ], "additional_components": [ "SPAC869.08" ] }, "reaction_10745717": { "compartment": "compartment_70101", "id": "reaction_10745717", "reactome": "R-SPO-5358484", "name": "DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745706", "species_71284" ], "products": [ "species_71285", "species_10745709" ], "modifiers": [ [ "species_10745714", "catalyst" ] ], "additional_components": [ "SPAC513.01c", "SPAC513.01c", "SPCC576.14" ] }, "reaction_10749267": { "compartment": "compartment_70101", "id": "reaction_10749267", "reactome": "R-SPO-5690152", "name": "USP5 cleaves polyubiquitin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10749262", "species_29356" ], "products": [ "species_10749264", "species_10729165" ], "modifiers": [ [ "species_10749262", "catalyst" ] ], "additional_components": [ "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q11119", "SPBC6B1.06c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q11119", "SPBC6B1.06c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "Q11119", "SPBC6B1.06c", "P0CH06", "SPAC11G7.04" ] }, "reaction_10734729": { "compartment": "compartment_70101", "id": "reaction_10734729", "reactome": "R-SPO-156913", "name": "Regeneration of eEF1A:GTP by eEF1B activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10734720", "species_10734724" ], "products": [ "species_10734706", "species_10734726" ], "modifiers": [ [ "species_10734720", "catalyst" ] ], "additional_components": [ "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04", "species_29420", "P0CT53", "SPCC794.09c", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "P0CT53", "SPCC794.09c", "species_29438", "P0CT55", "SPBC839.15c", "P0CT54", "SPAC23A1.10", "species_29420", "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04", "P40921", "SPAC29A4.02c", "O74173", "SPCC1450.04" ] }, "reaction_10745703": { "compartment": "compartment_70101", "id": "reaction_10745703", "reactome": "R-SPO-5358475", "name": "DPH6 ligates ammonium to diphthine-EEF2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745695", "species_113592", "species_31633" ], "products": [ "species_10734735", "species_111294", "species_76577" ], "modifiers": [ [ "species_10745700", "catalyst" ] ], "additional_components": [ "SPAC513.01c", "SPAC513.01c", "SPBC577.12" ] }, "reaction_10744614": { "compartment": "compartment_7660", "id": "reaction_10744614", "reactome": "R-SPO-3900047", "name": "SUMOylation of DDX17 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10744604" ], "products": [ "species_10743639", "species_10744612" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBP8B7.16c", "SPAC30D11.13", "O13351", "SPBC365.06", "P24782", "SPBP8B7.16c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10734687": { "compartment": "compartment_70101", "id": "reaction_10734687", "reactome": "R-SPO-156826", "name": "Dissociation of L13a from the 60s ribosomal subunit", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732216" ], "products": [ "species_10734685", "species_10731937" ], "modifiers": [], "additional_components": [ "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "P0C016", "SPAC6G10.11c", "O42706", "SPAC959.08", "P0C8R3", "SPAC589.10c", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O14388", "SPBC685.07c", "Q09668", "SPAC11E3.15", "P52822", "SPAC3H5.12c", "P36584", "SPAPB8E5.06c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P05733", "SPCC1223.05c", "Q9P784", "SPBC1711.06", "O74864", "SPCC18.14c", "O60143", "SPBC18H10.12c", "P0CT77", "SPAC26A3.07c", "P0CT61", "SPCC1322.11", "P79015", "SPAC3H5.10", "P35679", "SPBP8B7.03c", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "O14069", "SPAC1687.06c", "Q09127", "SPBC18E5.04", "P0CT72", "SPBC839.04", "P08094", "SPBP8B7.06", "O94238", "SPAC1805.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "Q9P769", "SPAP7G5.05", "P0CT68", "SPAC3A12.10", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "Q9USR7", "SPBC577.02", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O74904", "SPCC613.05c", "O42699", "SPCC1682.14", "P40372", "SPAC17A5.03", "P0CT83", "SPCC16C4.13c", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07", "Q9US22", "SPAC1783.08c", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "P0C016", "SPAC6G10.11c", "O42706", "SPAC959.08", "P0C8R3", "SPAC589.10c", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "P79071", "SPCC622.18", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O14388", "SPBC685.07c", "Q09668", "SPAC11E3.15", "P52822", "SPAC3H5.12c", "P36584", "SPAPB8E5.06c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P05733", "SPCC1223.05c", "Q9P784", "SPBC1711.06", "O74864", "SPCC18.14c", "O60143", "SPBC18H10.12c", "P0CT77", "SPAC26A3.07c", "P0CT61", "SPCC1322.11", "P79015", "SPAC3H5.10", "P35679", "SPBP8B7.03c", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "O14069", "SPAC1687.06c", "Q09127", "SPBC18E5.04", "P0CT72", "SPBC839.04", "P08094", "SPBP8B7.06", "O94238", "SPAC1805.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "Q9P769", "SPAP7G5.05", "P0CT68", "SPAC3A12.10", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "Q9USR7", "SPBC577.02", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O74904", "SPCC613.05c", "O42699", "SPCC1682.14", "P40372", "SPAC17A5.03", "P0CT83", "SPCC16C4.13c", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07", "Q9US22", "SPAC1783.08c", "O42848", "SPAC23A1.11", "O42991", "SPBC839.13c" ] }, "reaction_10750104": { "compartment": "compartment_70101", "id": "reaction_10750104", "reactome": "R-SPO-6781779", "name": "USP13 deubiquitinates BECN1,USP10", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750099", "species_29356" ], "products": [ "species_10735397", "species_10750101" ], "modifiers": [ [ "species_10750099", "catalyst" ] ], "additional_components": [ "Q11119", "SPBC6B1.06c", "P87117", "SPAC20G8.10c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q11119", "SPBC6B1.06c", "P87117", "SPAC20G8.10c", "Q11119", "SPBC6B1.06c", "P87117", "SPAC20G8.10c" ] }, "reaction_10734783": { "compartment": "compartment_17957", "id": "reaction_10734783", "reactome": "R-SPO-162683", "name": "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_75967", "species_8855661" ], "products": [ "species_76194", "species_8855666" ], "modifiers": [ [ "species_10734780", "catalyst" ] ], "additional_components": [ "SPAC144.10c" ] }, "reaction_10744969": { "compartment": "compartment_7660", "id": "reaction_10744969", "reactome": "R-SPO-4615889", "name": "SUMOylation of HDAC1 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10741535" ], "products": [ "species_10743639", "species_10744967" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC36.05c", "SPAC30D11.13", "O59702", "SPBC36.05c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10747799": { "compartment": "compartment_70101", "id": "reaction_10747799", "reactome": "R-SPO-5689539", "name": "ADRM1:26S proteaseome binds USP14", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747795", "species_10746685" ], "products": [ "species_10747797" ], "modifiers": [], "additional_components": [ "SPAC6G9.08", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13", "Q92353", "SPAC6G9.08", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "Q9Y7Y6", "SPBC342.04", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10745017": { "compartment": "compartment_7660", "id": "reaction_10745017", "reactome": "R-SPO-4641345", "name": "SUMOylation of TOP2B with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743647", "species_10745008" ], "products": [ "species_10743639", "species_10745015" ], "modifiers": [ [ "species_10743647", "catalyst" ] ], "additional_components": [ "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "SPBC1A4.03c", "SPAC30D11.13", "P08096", "SPBC1A4.03c", "O13351", "SPBC365.06", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13" ] }, "reaction_10749279": { "compartment": "compartment_7660", "id": "reaction_10749279", "reactome": "R-SPO-5690157", "name": "USP16,USP21 deubiquitinate Histone H2A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_10749274" ], "products": [ "species_10729044", "species_10749276" ], "modifiers": [ [ "species_10749274", "catalyst" ] ], "additional_components": [ "P04910", "SPAC19G12.06c", "Q9P7S5", "SPAC23G3.08c", "P04909", "SPCC622.08c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "P04910", "SPAC19G12.06c", "Q9P7S5", "SPAC23G3.08c", "P04909", "SPCC622.08c", "P04910", "SPAC19G12.06c", "Q9P7S5", "SPAC23G3.08c", "P04909", "SPCC622.08c" ] }, "reaction_10755134": { "compartment": "compartment_70101", "id": "reaction_10755134", "reactome": "R-SPO-8870461", "name": "RABGGTA and RABGGTB bind", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755130", "species_10755128" ], "products": [ "species_10755132" ], "modifiers": [], "additional_components": [ "SPAC167.02", "SPCC1620.05", "O94412", "SPCC1620.05", "P46960", "SPAC167.02" ] }, "reaction_10739595": { "compartment": "compartment_17957", "id": "reaction_10739595", "reactome": "R-SPO-446215", "name": "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449315", "species_449229" ], "products": [ "species_449311", "species_449312" ], "modifiers": [ [ "species_10739592", "catalyst" ] ], "additional_components": [ "SPAC1834.05" ] }, "reaction_10755762": { "compartment": "compartment_7660", "id": "reaction_10755762", "reactome": "R-SPO-8932221", "name": "METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10731070" ], "products": [ "species_10755754", "species_77502" ], "modifiers": [ [ "species_10755759", "catalyst" ] ], "additional_components": [ "SPAC13G7.02c", "SPAC13G7.02c", "SPAC23C4.06c" ] }, "reaction_10739579": { "compartment": "compartment_12045", "id": "reaction_10739579", "reactome": "R-SPO-446208", "name": "Addition of a second mannose to the N-glycan precursor by ALG2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_162860", "species_449283" ], "products": [ "species_449737", "species_29420" ], "modifiers": [ [ "species_10739576", "catalyst" ] ], "additional_components": [ "SPBC11B10.01" ] }, "reaction_10739682": { "compartment": "compartment_70101", "id": "reaction_10739682", "reactome": "R-SPO-449715", "name": "GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29512" ], "products": [ "species_29404", "species_449701" ], "modifiers": [ [ "species_10739679", "catalyst" ] ], "additional_components": [ "Q09740", "SPBC12C2.11" ] }, "reaction_10744836": { "compartment": "compartment_13231", "id": "reaction_10744836", "reactome": "R-SPO-4551649", "name": "RANBP2 SUMOylates RANBP2 with SUMO1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744823", "species_10743647" ], "products": [ "species_10744833", "species_10743639" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "SPBC1773.07c", "O13351", "SPBC365.06", "P40984", "SPAC30D11.13", "O13351", "SPBC365.06", "Q09717", "SPBC1773.07c", "SPAC30D11.13", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10739480": { "compartment": "compartment_70101", "id": "reaction_10739480", "reactome": "R-SPO-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_449703" ], "products": [ "species_532204" ], "modifiers": [ [ "species_10739477", "catalyst" ] ], "additional_components": [ "SPAC13C5.05c" ] }, "reaction_10738916": { "compartment": "compartment_70101", "id": "reaction_10738916", "reactome": "R-SPO-426520", "name": "Endonucleolytic RISC hydrolyzes target RNAs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_426523" ], "products": [ "species_426511" ], "modifiers": [ [ "species_10738891", "catalyst" ] ], "additional_components": [ "O74957", "SPCC736.11" ] }, "reaction_10745975": { "compartment": "compartment_70101", "id": "reaction_10745975", "reactome": "R-SPO-5578744", "name": "Importin-8 imports AGO2:miRNA into the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745968", "species_10745948" ], "products": [ "species_10745956", "species_10745972" ], "modifiers": [ [ "species_10733155", "catalyst" ] ], "additional_components": [ "P28748", "SPBC1289.03c", "species_29438", "O59809", "SPCC550.11", "O74957", "SPCC736.11", "O74957", "SPCC736.11", "O59809", "SPCC550.11", "P28748", "SPBC1289.03c", "species_29438", "P78847", "SPCC290.03c", "O74315", "SPBC15D4.10c", "P41838", "SPBC16A3.05c", "Q9UUE5", "SPBC17G9.04c", "Q09717", "SPBC1773.07c", "Q10099", "SPAC15F9.02", "O13838", "SPAC19E9.01c", "O36030", "SPAC4F10.18", "Q9USL4", "SPCC18B5.07c", "Q9UTH0", "SPAC1805.04", "O13961", "SPAC1786.03", "O42963", "SPBC19G7.15", "O94418", "SPCC1620.11", "Q10331", "SPBC428.01c", "Q09904", "SPAC30D11.04c", "Q9UTK4", "SPAC1486.05", "Q9URX8", "SPAC890.06", "Q10168", "SPAC26A3.15c", "Q9P7M8", "SPAP27G11.10c", "O13856", "SPAC1A6.02", "O74424", "SPCC162.08c", "Q9P382", "SPBC13A2.02", "O94319", "SPBC215.15", "Q09793", "SPAC22G7.09c", "O43044", "SPBC3B9.16c" ] }, "reaction_10745966": { "compartment": "compartment_7660", "id": "reaction_10745966", "reactome": "R-SPO-5578742", "name": "AGO1,2:small RNA complexes interact with chromatin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745962", "species_10730706", "species_10737547" ], "products": [ "species_10745964" ], "modifiers": [], "additional_components": [ "O74957", "SPCC736.11", "Q02061", "SPAC23G3.01", "P36594", "SPBC28F2.12", "P36595", "SPCC1020.04c", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O13877", "SPAC1B3.12c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O14459", "SPACUNK4.06c", "O74825", "SPBC337.14", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "P09988", "SPAC1834.04", "Q02061", "SPAC23G3.01", "P09322", "SPAC1834.03c", "P36595", "SPCC1020.04c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "O74957", "SPCC736.11", "P04909", "SPCC622.08c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P48003", "SPBC11B10.10c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10757019": { "compartment": "compartment_70101", "id": "reaction_10757019", "reactome": "R-SPO-9023909", "name": "C3PO hydrolyzes cleaved passenger strand", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757004" ], "products": [ "species_10738889" ], "modifiers": [ [ "species_10757016", "catalyst" ] ], "additional_components": [ "O74957", "SPCC736.11", "O74957", "SPCC736.11", "O74955", "SPCC736.09c", "Q9P7V3", "SPAC30.03c" ] }, "reaction_10745950": { "compartment": "compartment_70101", "id": "reaction_10745950", "reactome": "R-SPO-5578712", "name": "Importin-8 binds AGO2:miRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738887", "species_10745946" ], "products": [ "species_10745948" ], "modifiers": [], "additional_components": [ "O74957", "SPCC736.11", "SPCC550.11", "O59809", "SPCC550.11", "O74957", "SPCC736.11" ] }, "reaction_10757024": { "compartment": "compartment_70101", "id": "reaction_10757024", "reactome": "R-SPO-9023912", "name": "AGO2 cleaves passenger strand of duplex siRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757021" ], "products": [ "species_10757004" ], "modifiers": [ [ "species_10757021", "catalyst" ] ], "additional_components": [ "O74957", "SPCC736.11", "O74957", "SPCC736.11", "O74957", "SPCC736.11" ] }, "reaction_10732342": { "compartment": "compartment_70101", "id": "reaction_10732342", "reactome": "R-SPO-73608", "name": "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500829", "species_29356" ], "products": [ "species_31633", "species_500430" ], "modifiers": [ [ "species_10732339", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:15698", "CHEBI:16704", "CHEBI:16450", "Q09190", "SPAC1556.04c", "species_442320" ] }, "reaction_10756398": { "compartment": "compartment_70101", "id": "reaction_10756398", "reactome": "R-SPO-8954327", "name": "UCKL1 phosphorylates urindine, cytidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_500759", "species_113592" ], "products": [ "species_29370", "species_500761" ], "modifiers": [ [ "species_10756395", "catalyst" ] ], "additional_components": [ "CHEBI:17562", "CHEBI:16704", "species_109395", "species_418075", "SPCC162.11c" ] }, "reaction_10750462": { "compartment": "compartment_70101", "id": "reaction_10750462", "reactome": "R-SPO-6788295", "name": "HDHD1:Mg2+ dephosphorylates PURIDP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6788291", "species_29356" ], "products": [ "species_29372", "species_6788290" ], "modifiers": [ [ "species_10750459", "catalyst" ] ], "additional_components": [ "O59760", "SPCC1020.07", "species_29926" ] }, "reaction_10736241": { "compartment": "compartment_70101", "id": "reaction_10736241", "reactome": "R-SPO-193052", "name": "Pregn-5-ene-3,20-dione isomerizes to progesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196344" ], "products": [ "species_193055" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10736360": { "compartment": "compartment_70101", "id": "reaction_10736360", "reactome": "R-SPO-196350", "name": "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193103", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196344" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10746449": { "compartment": "compartment_70101", "id": "reaction_10746449", "reactome": "R-SPO-5652195", "name": "SORD oxidizes D-sorbitol to Fru", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_5652213" ], "products": [ "species_70106", "species_73473", "species_29532" ], "modifiers": [ [ "species_10746446", "catalyst" ] ], "additional_components": [ "species_442320", "P36624", "SPBC1773.05c" ] }, "reaction_10746437": { "compartment": "compartment_70101", "id": "reaction_10746437", "reactome": "R-SPO-5652172", "name": "AKR1B1 reduces Glc to D-sorbitol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_70113" ], "products": [ "species_29366", "species_5652213" ], "modifiers": [ [ "species_10736354", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10729667": { "compartment": "compartment_70101", "id": "reaction_10729667", "reactome": "R-SPO-70349", "name": "DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_30393" ], "products": [ "species_29370", "species_29578" ], "modifiers": [ [ "species_10729664", "catalyst" ] ], "additional_components": [ "O74215", "SPAC977.16c", "species_29926" ] }, "reaction_10753479": { "compartment": "compartment_70101", "id": "reaction_10753479", "reactome": "R-SPO-6813749", "name": "ALDH1A1 oxidises GA to DGA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30393", "species_29360", "species_29356" ], "products": [ "species_70106", "species_73473", "species_6799497" ], "modifiers": [ [ "species_10730487", "catalyst" ] ], "additional_components": [ "O14293", "SPAC9E9.09c" ] }, "reaction_10745910": { "compartment": "compartment_7660", "id": "reaction_10745910", "reactome": "R-SPO-5423117", "name": "PHF8 demethylates MeK21-histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113671", "species_113685", "species_10743010" ], "products": [ "species_10732874", "species_159942", "species_159939", "species_29478" ], "modifiers": [ [ "species_10743019", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPCC622.16c" ] }, "reaction_10755942": { "compartment": "compartment_70101", "id": "reaction_10755942", "reactome": "R-SPO-8941895", "name": "Formation of CDK4/6:CCND complexes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733280", "species_10755938" ], "products": [ "species_10755940" ], "modifiers": [], "additional_components": [ "SPBC11B10.09", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10758108": { "compartment": "compartment_7660", "id": "reaction_10758108", "reactome": "R-SPO-9754129", "name": "CDK6 inhibitors bind CDK6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9754132", "species_10756021" ], "products": [ "species_10758106" ], "modifiers": [], "additional_components": [ "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10426", "P10815", "SPBC582.03", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "LigandDisplayForward?ligandId=7934" ] }, "reaction_10756036": { "compartment": "compartment_7660", "id": "reaction_10756036", "reactome": "R-SPO-8942836", "name": "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10756008" ], "products": [ "species_113582", "species_10756034" ], "modifiers": [ [ "species_10732457", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36613", "SPBP16F5.02", "O94684", "SPBC776.18c", "Q12126", "SPBC19F8.07" ] }, "reaction_10758118": { "compartment": "compartment_7660", "id": "reaction_10758118", "reactome": "R-SPO-9754130", "name": "CDK4 inhibitors bind CDK4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756032", "species_9754127" ], "products": [ "species_10758116" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "LigandDisplayForward?ligandId=7938", "LigandDisplayForward?ligandId=5950", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "pubchem.compound:9933545", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5680", "LigandDisplayForward?ligandId=7938", "LigandDisplayForward?ligandId=5950", "P36630", "SPAPB2B4.03", "LigandDisplayForward?ligandId=9923", "LigandDisplayForward?ligandId=11189", "LigandDisplayForward?ligandId=7380", "LigandDisplayForward?ligandId=5969", "LigandDisplayForward?ligandId=7379", "LigandDisplayForward?ligandId=10313", "LigandDisplayForward?ligandId=10426", "P10815", "SPBC582.03", "LigandDisplayForward?ligandId=5707", "LigandDisplayForward?ligandId=7744", "LigandDisplayForward?ligandId=9626", "LigandDisplayForward?ligandId=7383", "LigandDisplayForward?ligandId=7382", "P04551", "SPBC11B10.09", "pubchem.compound:9933545", "P25009", "SPBC19F5.01c", "LigandDisplayForward?ligandId=8203", "LigandDisplayForward?ligandId=7934", "LigandDisplayForward?ligandId=5680" ] }, "reaction_10756010": { "compartment": "compartment_13231", "id": "reaction_10756010", "reactome": "R-SPO-8942803", "name": "Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10755982" ], "products": [ "species_10756008" ], "modifiers": [], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c" ] }, "reaction_10733308": { "compartment": "compartment_70101", "id": "reaction_10733308", "reactome": "R-SPO-75849", "name": "Transport of Citrate from Mitochondrial Matrix to cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29654", "species_198498" ], "products": [ "species_76190", "species_113544" ], "modifiers": [ [ "species_10733305", "catalyst" ] ], "additional_components": [ "SPAC19G12.05" ] }, "reaction_10733300": { "compartment": "compartment_70101", "id": "reaction_10733300", "reactome": "R-SPO-75848", "name": "ACLY tetramer transforms CIT to Ac-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_76190", "species_113592" ], "products": [ "species_29370", "species_76213", "species_29372", "species_76183" ], "modifiers": [ [ "species_10733297", "catalyst" ] ], "additional_components": [ "O13907", "SPAC22A12.16" ] }, "reaction_10736846": { "compartment": "compartment_70101", "id": "reaction_10736846", "reactome": "R-SPO-200555", "name": "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111627", "species_76183" ], "products": [ "species_29370", "species_29372", "species_29508" ], "modifiers": [ [ "species_10733319", "catalyst" ], [ "species_76190", "catalyst" ] ], "additional_components": [ "SPAC56E4.04c" ] }, "reaction_10752466": { "compartment": "compartment_70101", "id": "reaction_10752466", "reactome": "R-SPO-6801109", "name": "CHM binds RGGT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752455", "species_10752462" ], "products": [ "species_10752464" ], "modifiers": [], "additional_components": [ "O94412", "SPCC1620.05", "P46960", "SPAC167.02", "SPBC15C4.03", "O94412", "SPCC1620.05", "P46960", "SPAC167.02", "O60112", "SPBC15C4.03" ] }, "reaction_10752457": { "compartment": "compartment_876", "id": "reaction_10752457", "reactome": "R-SPO-6801101", "name": "RABGGTA binds RABGGTB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752448", "species_10752453" ], "products": [ "species_10752455" ], "modifiers": [], "additional_components": [ "SPCC1620.05", "SPAC167.02", "O94412", "SPCC1620.05", "P46960", "SPAC167.02" ] }, "reaction_10746376": { "compartment": "compartment_7660", "id": "reaction_10746376", "reactome": "R-SPO-5651654", "name": "SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10743010" ], "products": [ "species_10746366", "species_77502" ], "modifiers": [ [ "species_10746371", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPCC4B3.12" ] }, "reaction_10746381": { "compartment": "compartment_7660", "id": "reaction_10746381", "reactome": "R-SPO-5651657", "name": "SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746366", "species_77087" ], "products": [ "species_10746379", "species_77502" ], "modifiers": [ [ "species_10746371", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPCC4B3.12" ] }, "reaction_10745162": { "compartment": "compartment_7660", "id": "reaction_10745162", "reactome": "R-SPO-5205798", "name": "PRMT1,PRMT6 methylate arginine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732874", "species_77087" ], "products": [ "species_10745159", "species_77502" ], "modifiers": [ [ "species_10743825", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPAC890.07c" ] }, "reaction_10746660": { "compartment": "compartment_7660", "id": "reaction_10746660", "reactome": "R-SPO-5661126", "name": "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745159", "species_77087" ], "products": [ "species_10746658", "species_77502" ], "modifiers": [ [ "species_10743825", "catalyst" ] ], "additional_components": [ "SPAC1834.03c", "SPAC1834.03c", "SPAC890.07c" ] }, "reaction_10743853": { "compartment": "compartment_7660", "id": "reaction_10743853", "reactome": "R-SPO-3215385", "name": "CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10743844" ], "products": [ "species_10743850" ], "modifiers": [ [ "species_10743844", "catalyst" ] ], "additional_components": [ "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P78963", "SPBC16H5.11c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P78963", "SPBC16H5.11c", "P36630", "SPAPB2B4.03", "P10815", "SPBC582.03", "P04551", "SPBC11B10.09", "P25009", "SPBC19F5.01c", "P78963", "SPBC16H5.11c" ] }, "reaction_10745307": { "compartment": "compartment_7660", "id": "reaction_10745307", "reactome": "R-SPO-5205867", "name": "PRMT1 methylates arginine-12 of histone H2A (H2AR11)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_77087", "species_10745271" ], "products": [ "species_77502", "species_10745305" ], "modifiers": [ [ "species_10743825", "catalyst" ] ], "additional_components": [ "P04910", "SPAC19G12.06c", "P04909", "SPCC622.08c", "P04910", "SPAC19G12.06c", "P04909", "SPCC622.08c", "SPAC890.07c" ] }, "reaction_10737810": { "compartment": "compartment_70101", "id": "reaction_10737810", "reactome": "R-SPO-350600", "name": "Antizyme inhibitor binds to OAZ and stablizes ODC complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737804", "species_10737795" ], "products": [ "species_10737808" ], "modifiers": [], "additional_components": [ "SPAC144.04c", "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c", "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c" ] }, "reaction_10737980": { "compartment": "compartment_70101", "id": "reaction_10737980", "reactome": "R-SPO-353125", "name": "26S proteosome degrades ODC holoenzyme complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10737795" ], "products": [ "species_10737789" ], "modifiers": [ [ "species_10729366", "catalyst" ] ], "additional_components": [ "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c", "SPBC577.14c", "O94444", "SPAC637.10c", "Q9P7S2", "SPAC23G3.11", "O74445", "SPCC1682.16", "O14126", "SPAC3A11.12c", "O42897", "SPBC119.01", "O94393", "SPAC2H10.02c", "P50524", "SPBC16G5.01", "O74894", "SPCC576.10c", "P0CU18", "SPAPB8E5.02c", "O14250", "SPAC6G10.04c", "O42931", "SPBC16C6.07c", "Q09841", "SPAC23D3.07", "P0CU17", "SPAC1420.03", "O94517", "SPBC646.16", "O74762", "SPBC17D11.07c", "O94579", "SPCC1442.06", "P36612", "SPBC4.07c", "Q9Y7T8", "SPCC63.12c", "O43063", "SPBC4C3.10c", "P30655", "SPAC4A8.13c", "Q9UQY2", "SPAC22F8.06", "O74440", "SPCC1682.10", "O59770", "SPCC1795.04c", "Q10335", "SPBC582.07c", "P41836", "SPBC23G7.12c", "Q9UT97", "SPAC323.02c", "O74867", "SPCC18.17c", "P87048", "SPBP19A11.03c", "Q9USQ9", "SPBC577.10", "Q09720", "SPAC31A2.04c", "Q10329", "SPBC106.16", "Q9UTI1", "SPAC15E1.10", "Q09682", "SPAC13C5.01c", "Q9US13", "SPAC607.05", "P41878", "SPAC31G5.13" ] }, "reaction_10737797": { "compartment": "compartment_70101", "id": "reaction_10737797", "reactome": "R-SPO-350567", "name": "Antizyme OAZ binds to Ornithine decarboxylase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10730038", "species_10737789" ], "products": [ "species_10737795" ], "modifiers": [], "additional_components": [ "SPAC144.04c", "SPBC577.14c", "Q9UQW9", "SPAC144.04c", "Q9USQ5", "SPBC577.14c" ] }, "reaction_10752439": { "compartment": "compartment_7660", "id": "reaction_10752439", "reactome": "R-SPO-6800490", "name": "ATM phosphorylates PIDD1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10752434" ], "products": [ "species_113582", "species_10752437" ], "modifiers": [ [ "species_10737781", "catalyst" ] ], "additional_components": [ "SPBC19C7.03", "SPBC19C7.03", "SPCC23B6.03c" ] }, "reaction_10752490": { "compartment": "compartment_17906", "id": "reaction_10752490", "reactome": "R-SPO-6801250", "name": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1500590" ], "products": [ "species_1524101" ], "modifiers": [ [ "species_10752485", "catalyst" ] ], "additional_components": [ "Q96VG1", "SPBC119.18", "O59707", "SPBC36.10", "Q9UT07", "SPAP8A3.10" ] }, "reaction_10752443": { "compartment": "compartment_70101", "id": "reaction_10752443", "reactome": "R-SPO-6800793", "name": "PIDD1 translocates to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752437" ], "products": [ "species_10752441" ], "modifiers": [], "additional_components": [ "SPBC19C7.03", "SPBC19C7.03" ] }, "reaction_10752487": { "compartment": "compartment_17927", "id": "reaction_10752487", "reactome": "R-SPO-6801242", "name": "TRIAP1 binds PRELID1, PRELID3A", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10752471", "species_10752483" ], "products": [ "species_10752485" ], "modifiers": [], "additional_components": [ "SPBC119.18", "O59707", "SPBC36.10", "Q9UT07", "SPAP8A3.10", "Q96VG1", "SPBC119.18", "O59707", "SPBC36.10", "Q9UT07", "SPAP8A3.10" ] }, "reaction_10746130": { "compartment": "compartment_70101", "id": "reaction_10746130", "reactome": "R-SPO-5618331", "name": "HDAC6 deacetylates microtubules", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76194", "species_10746127" ], "products": [ "species_10738115", "species_76183" ], "modifiers": [ [ "species_10745603", "catalyst" ] ], "additional_components": [ "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "species_29420", "P04689", "SPBC800.05c", "P05219", "SPBC26H8.07c", "P04688", "SPBC16A3.15c", "species_29438", "SPBC800.03" ] }, "reaction_10743065": { "compartment": "compartment_20699", "id": "reaction_10743065", "reactome": "R-SPO-2214351", "name": "PLK1 phosphorylates GORASP1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10743057" ], "products": [ "species_29370", "species_10743062" ], "modifiers": [ [ "species_10743057", "catalyst" ] ], "additional_components": [ "Q10149", "SPAC1D4.02c", "P11620", "SPBC1703.10", "P50528", "SPAC23C11.16", "species_29438", "Q10149", "SPAC1D4.02c", "P11620", "SPBC1703.10", "P50528", "SPAC23C11.16", "species_29438", "Q10149", "SPAC1D4.02c", "P11620", "SPBC1703.10", "P50528", "SPAC23C11.16", "species_29438" ] }, "reaction_10757878": { "compartment": "compartment_17906", "id": "reaction_10757878", "reactome": "R-SPO-9693214", "name": "RHOD binds effectors at the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756754", "species_10757872" ], "products": [ "species_10757876" ], "modifiers": [], "additional_components": [ "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q10056", "SPAC1F5.09c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "P50527", "SPBC1604.14c" ] }, "reaction_10746782": { "compartment": "compartment_70101", "id": "reaction_10746782", "reactome": "R-SPO-5668932", "name": "PAK2 phosphorylates myosin regulatory light chain (MRLC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10746773" ], "products": [ "species_29370", "species_10746779" ], "modifiers": [ [ "species_10746316", "catalyst" ] ], "additional_components": [ "Q9USI6", "SPCC645.05c", "Q09196", "SPAP8A3.08", "Q9UUG5", "SPAC926.03", "O14157", "SPAC4A8.05c", "Q9USI6", "SPCC645.05c", "Q09196", "SPAP8A3.08", "Q9UUG5", "SPAC926.03", "O14157", "SPAC4A8.05c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c" ] }, "reaction_10756841": { "compartment": "compartment_876", "id": "reaction_10756841", "reactome": "R-SPO-9013437", "name": "RHOD GAPs stimulate RHOD GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831", "species_29356" ], "products": [ "species_10756817", "species_29372" ], "modifiers": [ [ "species_10756838", "catalyst" ] ], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757894": { "compartment": "compartment_876", "id": "reaction_10757894", "reactome": "R-SPO-9693243", "name": "RHOD translocates to the Golgi membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831" ], "products": [ "species_10757892" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10756608": { "compartment": "compartment_7660", "id": "reaction_10756608", "reactome": "R-SPO-9009533", "name": "TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732619", "species_10732432", "species_10756604" ], "products": [ "species_10756606" ], "modifiers": [], "additional_components": [ "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "SPAC3A11.12c", "O43058", "SPBC4C3.12", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "P24782", "SPBP8B7.16c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "CHEBI:27974", "species_193066", "Q9USU9", "SPBC28F2.09", "O43058", "SPBC4C3.12", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "P17871", "SPAC3A11.12c", "species_193132", "P24782", "SPBP8B7.16c", "O74948", "SPCC553.11c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "CHEBI:27974", "species_193066" ] }, "reaction_10756525": { "compartment": "compartment_70101", "id": "reaction_10756525", "reactome": "R-SPO-8981931", "name": "RAC1 and CDC42 activate PAK2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738343", "species_10738231" ], "products": [ "species_10746302", "species_10738341" ], "modifiers": [], "additional_components": [ "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q10056", "SPAC1F5.09c", "P50527", "SPBC1604.14c" ] }, "reaction_10746286": { "compartment": "compartment_70101", "id": "reaction_10746286", "reactome": "R-SPO-5626469", "name": "GTP-bound RAC1 and CDC42 bind IQGAPs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746282", "species_10738231" ], "products": [ "species_10746284" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "O14188", "SPAC4F8.13c", "Q01112", "SPAC110.03", "species_29438", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "O14188", "SPAC4F8.13c", "species_29438" ] }, "reaction_10757002": { "compartment": "compartment_7660", "id": "reaction_10757002", "reactome": "R-SPO-9023861", "name": "PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756606", "species_10743825" ], "products": [ "species_10756994" ], "modifiers": [], "additional_components": [ "Q9USU9", "SPBC28F2.09", "O43058", "SPBC4C3.12", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "P17871", "SPAC3A11.12c", "species_193132", "P24782", "SPBP8B7.16c", "O74948", "SPCC553.11c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "CHEBI:27974", "species_193066", "SPAC890.07c", "O43058", "SPBC4C3.12", "P17871", "SPAC3A11.12c", "P24782", "SPBP8B7.16c", "Q9URX7", "SPAC890.07c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "Q9USU9", "SPBC28F2.09", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "O74948", "SPCC553.11c", "CHEBI:27974", "species_193066" ] }, "reaction_10746295": { "compartment": "compartment_876", "id": "reaction_10746295", "reactome": "R-SPO-5626549", "name": "IQGAPs bind CALM1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746284", "species_10737009" ], "products": [ "species_10746290" ], "modifiers": [], "additional_components": [ "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "O14188", "SPAC4F8.13c", "species_29438", "P05933", "SPAC3A12.14", "species_74016", "O14008", "SPAC29A4.05", "P05933", "SPAC3A12.14", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "species_74016", "O14188", "SPAC4F8.13c", "O14008", "SPAC29A4.05", "species_29438" ] }, "reaction_10756782": { "compartment": "compartment_876", "id": "reaction_10756782", "reactome": "R-SPO-9013158", "name": "CDC42 GDIs block activation of CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756776", "species_10756778" ], "products": [ "species_10756780" ], "modifiers": [], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "O14224", "SPAC6F12.06", "species_29420", "Q01112", "SPAC110.03", "O14224", "SPAC6F12.06" ] }, "reaction_10758013": { "compartment": "compartment_876", "id": "reaction_10758013", "reactome": "R-SPO-9726862", "name": "Phosphorylated RHOU translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10758007" ], "products": [ "species_10758011" ], "modifiers": [], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "species_29420", "Q01112", "SPAC110.03" ] }, "reaction_10756867": { "compartment": "compartment_876", "id": "reaction_10756867", "reactome": "R-SPO-9013438", "name": "RHOD binds effectors at the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756855", "species_10756863" ], "products": [ "species_10756865" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "O13995", "SPAC25B8.01", "Q09195", "SPBC16G5.18", "Q10311", "SPAC6C3.08", "O13995", "SPAC25B8.01", "Q09195", "SPBC16G5.18", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "Q10311", "SPAC6C3.08", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10757000": { "compartment": "compartment_7660", "id": "reaction_10757000", "reactome": "R-SPO-9023860", "name": "Histone acetyltransferases are recruited to the TFF1 gene", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756996", "species_10756988" ], "products": [ "species_10756998" ], "modifiers": [], "additional_components": [ "O43058", "SPBC4C3.12", "P17871", "SPAC3A11.12c", "P24782", "SPBP8B7.16c", "Q9URX7", "SPAC890.07c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "Q9USU9", "SPBC28F2.09", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "O74948", "SPCC553.11c", "CHEBI:27974", "species_193066", "Q10325", "SPAC17G8.13c", "Q9UUK2", "SPAC1952.05", "O43058", "SPBC4C3.12", "Q10325", "SPAC17G8.13c", "P17871", "SPAC3A11.12c", "P24782", "SPBP8B7.16c", "Q9URX7", "SPAC890.07c", "Q10280", "SPCC1902.01", "Q10134", "SPAC23E2.01", "Q9USU9", "SPBC28F2.09", "CHEBI:142773", "O94720", "SPCC1393.08", "O13606", "SPBC32H8.11", "species_193132", "O74948", "SPCC553.11c", "Q9UUK2", "SPAC1952.05", "CHEBI:27974", "species_193066" ] }, "reaction_10756484": { "compartment": "compartment_70101", "id": "reaction_10756484", "reactome": "R-SPO-8980691", "name": "RHOA GEFs activate RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10734490" ], "products": [ "species_10734492", "species_29420" ], "modifiers": [ [ "species_10738645", "catalyst" ] ], "additional_components": [ "species_29420", "Q09914", "SPAC1F7.04", "Q09914", "SPAC1F7.04", "species_29438", "Q9USU1", "SPBC336.03", "P26674", "SPCC1442.01" ] }, "reaction_10746292": { "compartment": "compartment_70101", "id": "reaction_10746292", "reactome": "R-SPO-5626507", "name": "IQGAPs bind F-actin, which is inhibited by calmodulin", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10746284", "species_10742720" ], "products": [ "species_10746288" ], "modifiers": [ [ "species_10746290", "inhibitor" ] ], "additional_components": [ "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "O14188", "SPAC4F8.13c", "species_29438", "species_113592", "O60054", "SPBC56F2.03", "P10989", "SPBC32H8.12c", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "species_113592", "O60054", "SPBC56F2.03", "O14188", "SPAC4F8.13c", "P10989", "SPBC32H8.12c", "species_29438", "P05933", "SPAC3A12.14", "Q10201", "SPBC17D1.07c", "Q01112", "SPAC110.03", "species_74016", "O14188", "SPAC4F8.13c", "O14008", "SPAC29A4.05", "species_29438" ] }, "reaction_10756869": { "compartment": "compartment_876", "id": "reaction_10756869", "reactome": "R-SPO-9013452", "name": "RHOD:GTP translocates to the endosome membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831" ], "products": [ "species_10756855" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10756701": { "compartment": "compartment_876", "id": "reaction_10756701", "reactome": "R-SPO-9013009", "name": "RHOA binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734492", "species_10756697" ], "products": [ "species_10756699" ], "modifiers": [], "additional_components": [ "Q09914", "SPAC1F7.04", "species_29438", "O74534", "SPCC74.01", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O43027", "SPBC354.13", "O74498", "SPCC285.11", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "P36583", "SPBC12D12.04c", "O14188", "SPAC4F8.13c", "O74786", "SPBC26H8.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c", "O74534", "SPCC74.01", "Q10201", "SPBC17D1.07c", "P78953", "SPCC4B3.15", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "Q09706", "SPAC2F7.16c", "O43027", "SPBC354.13", "species_29438", "O74498", "SPCC285.11", "O94675", "SPBC776.07", "Q9P3B1", "SPAC1565.02c", "P36583", "SPBC12D12.04c", "O14188", "SPAC4F8.13c", "O74786", "SPBC26H8.02c", "O43023", "SPBC354.09c", "P36582", "SPAC17G8.14c" ] }, "reaction_10757843": { "compartment": "compartment_876", "id": "reaction_10757843", "reactome": "R-SPO-9692800", "name": "CDC42 translocates to the endoplasmic reticulum membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738231" ], "products": [ "species_10757841" ], "modifiers": [], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "Q01112", "SPAC110.03", "species_29438" ] }, "reaction_10756625": { "compartment": "compartment_7660", "id": "reaction_10756625", "reactome": "R-SPO-9011949", "name": "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756620" ], "products": [ "species_10747338", "species_10756622" ], "modifiers": [ [ "species_10756620", "catalyst" ] ], "additional_components": [ "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "O94691", "SPBC83.07", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "CHEBI:50114", "SPBC83.07", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "CHEBI:50114", "P09988", "SPAC1834.04", "P09322", "SPAC1834.03c", "P04910", "SPAC19G12.06c", "P04913", "SPCC622.09", "O94691", "SPBC83.07", "P48003", "SPBC11B10.10c", "P04909", "SPCC622.08c", "CHEBI:50114" ] }, "reaction_10756686": { "compartment": "compartment_876", "id": "reaction_10756686", "reactome": "R-SPO-9013006", "name": "RHOA:GTP translocates to the ER membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734492" ], "products": [ "species_10756684" ], "modifiers": [], "additional_components": [ "Q09914", "SPAC1F7.04", "species_29438", "Q09914", "SPAC1F7.04", "species_29438" ] }, "reaction_10756523": { "compartment": "compartment_70101", "id": "reaction_10756523", "reactome": "R-SPO-8981926", "name": "RAC1 and CDC42 activate PAK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738231", "species_10738347" ], "products": [ "species_10746304", "species_10738345" ], "modifiers": [], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "Q01112", "SPAC110.03", "species_29438", "P50527", "SPBC1604.14c", "SPBC1604.14c" ] }, "reaction_10756658": { "compartment": "compartment_7660", "id": "reaction_10756658", "reactome": "R-SPO-9012319", "name": "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10756653" ], "products": [ "species_113582", "species_10756655" ], "modifiers": [ [ "species_10756653", "catalyst" ] ], "additional_components": [ "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O14098", "SPAC2F3.15", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "CHEBI:50114", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O59748", "SPBC530.13", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O14098", "SPAC2F3.15", "O13877", "SPAC1B3.12c", "CHEBI:50114", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O59748", "SPBC530.13", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O14098", "SPAC2F3.15", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "CHEBI:50114", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O59748", "SPBC530.13", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10756519": { "compartment": "compartment_70101", "id": "reaction_10756519", "reactome": "R-SPO-8981637", "name": "RHOA GAPs stimulate RHOA GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734492", "species_29356" ], "products": [ "species_29372", "species_10734490" ], "modifiers": [ [ "species_10756516", "catalyst" ] ], "additional_components": [ "Q09914", "SPAC1F7.04", "species_29438", "species_29420", "Q09914", "SPAC1F7.04", "O74335", "SPBC17F3.01c", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757377": { "compartment": "compartment_70101", "id": "reaction_10757377", "reactome": "R-SPO-9626816", "name": "PIN1 binds p-S345-NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757370", "species_10757372" ], "products": [ "species_10757374" ], "modifiers": [ [ "species_10757372", "catalyst" ] ], "additional_components": [ "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "SPCC16C4.03", "O74448", "SPCC16C4.03", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "SPCC16C4.03" ] }, "reaction_10746044": { "compartment": "compartment_5263232", "id": "reaction_10746044", "reactome": "R-SPO-5610749", "name": "cAMP dissociates PKA, promoting GLI processing", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30389", "species_10746040" ], "products": [ "species_10746034", "species_10746042" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "P40376", "SPBC106.10", "SPBC106.10", "P36600", "SPAC8C9.03", "species_30389" ] }, "reaction_10756834": { "compartment": "compartment_876", "id": "reaction_10756834", "reactome": "R-SPO-9013435", "name": "RHOD auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756817" ], "products": [ "species_10756831", "species_29420" ], "modifiers": [ [ "species_10756817", "catalyst" ] ], "additional_components": [ "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "species_29420", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01" ] }, "reaction_10756918": { "compartment": "compartment_876", "id": "reaction_10756918", "reactome": "R-SPO-9018768", "name": "RHOU auto-activates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756915" ], "products": [ "species_10756895", "species_29420" ], "modifiers": [ [ "species_10756915", "catalyst" ] ], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "Q01112", "SPAC110.03", "species_29438", "species_29420", "Q01112", "SPAC110.03" ] }, "reaction_10756793": { "compartment": "compartment_876", "id": "reaction_10756793", "reactome": "R-SPO-9013159", "name": "CDC42 GEFs activate CDC42", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29438", "species_10756776" ], "products": [ "species_29420", "species_10738231" ], "modifiers": [ [ "species_10756790", "catalyst" ] ], "additional_components": [ "species_29420", "Q01112", "SPAC110.03", "Q01112", "SPAC110.03", "species_29438", "Q09763", "SPAC24H6.09", "O59679", "SPBC29A3.17", "Q9USU1", "SPBC336.03", "Q9HGL2", "SPBC800.10c", "P26674", "SPCC1442.01", "Q04665", "SPAC23H3.13c" ] }, "reaction_10745852": { "compartment": "compartment_12045", "id": "reaction_10745852", "reactome": "R-SPO-5362412", "name": "SYVN1 ubiquitinates Hh C-terminal fragments", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10745845", "species_10729165" ], "products": [ "species_10745849" ], "modifiers": [ [ "species_10745845", "catalyst" ] ], "additional_components": [ "O13875", "SPAC1B3.10c", "Q9UTC8", "SPAC227.11c", "Q9P3A7", "SPAC1565.08", "O74757", "SPBC17D11.02c", "O94458", "SPAC1687.17c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0C8R3", "SPAC589.10c", "P0CH06", "SPAC11G7.04", "Q9UTC8", "SPAC227.11c", "O13875", "SPAC1B3.10c", "Q9P3A7", "SPAC1565.08", "O74757", "SPBC17D11.02c", "O94458", "SPAC1687.17c", "O13875", "SPAC1B3.10c", "Q9UTC8", "SPAC227.11c", "Q9P3A7", "SPAC1565.08", "O74757", "SPBC17D11.02c", "O94458", "SPAC1687.17c" ] }, "reaction_10756682": { "compartment": "compartment_70101", "id": "reaction_10756682", "reactome": "R-SPO-9012835", "name": "GDIs block activation of RHOA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756678", "species_10734490" ], "products": [ "species_10756680" ], "modifiers": [], "additional_components": [ "O14224", "SPAC6F12.06", "species_29420", "Q09914", "SPAC1F7.04", "species_29420", "Q09914", "SPAC1F7.04", "O14224", "SPAC6F12.06" ] }, "reaction_10757858": { "compartment": "compartment_70101", "id": "reaction_10757858", "reactome": "R-SPO-9693198", "name": "RHOD binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831", "species_10757854" ], "products": [ "species_10757856" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "O94655", "SPBC405.04c", "Q9HGP5", "SPAC631.01c", "Q10056", "SPAC1F5.09c", "O13728", "SPAC15A10.08", "Q92356", "SPAC6G9.11", "Q9P7E8", "SPAPJ760.02c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c", "Q7LKY2", "SPBC1289.14", "P50527", "SPBC1604.14c", "O13728", "SPAC15A10.08", "Q09914", "SPAC1F7.04", "Q92356", "SPAC6G9.11", "O43027", "SPBC354.13", "Q10133", "SPAC16.01", "species_29438", "Q9P3B1", "SPAC1565.02c", "Q7LKY2", "SPBC1289.14", "P50527", "SPBC1604.14c", "O94655", "SPBC405.04c", "Q9HGP5", "SPAC631.01c", "Q10056", "SPAC1F5.09c", "Q9HE04", "SPAC20H4.11c", "O13928", "SPAC23C4.08", "Q9P7E8", "SPAPJ760.02c", "Q874R1", "SPAC16A10.04" ] }, "reaction_10751276": { "compartment": "compartment_1222693", "id": "reaction_10751276", "reactome": "R-SPO-6798174", "name": "PIK3C3:PIK3R4 phosphorylates PI to PI3P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_1524165" ], "products": [ "species_29370", "species_1629751" ], "modifiers": [ [ "species_10751273", "catalyst" ] ], "additional_components": [ "O42900", "SPBC119.07", "P50520", "SPAC458.05" ] }, "reaction_10756913": { "compartment": "compartment_876", "id": "reaction_10756913", "reactome": "R-SPO-9018766", "name": "RHOU binds effectors at the plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756895", "species_10756909" ], "products": [ "species_10756911" ], "modifiers": [], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "Q9USZ0", "SPBC1306.02", "O74749", "SPBC1734.08", "Q9USR1", "SPBC577.08c", "O13728", "SPAC15A10.08", "Q9HGL2", "SPBC800.10c", "Q10172", "SPAC25G10.09c", "Q92462", "SPAC11G7.02", "O94478", "SPCC1919.11", "P50527", "SPBC1604.14c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "Q9UTG2", "SPAC1805.15c", "O14188", "SPAC4F8.13c", "O94685", "SPBC83.01", "O14326", "SPBC16E9.11c", "Q9USZ0", "SPBC1306.02", "O74749", "SPBC1734.08", "Q9USR1", "SPBC577.08c", "O13728", "SPAC15A10.08", "Q9HGL2", "SPBC800.10c", "species_29438", "Q10172", "SPAC25G10.09c", "Q92462", "SPAC11G7.02", "O94478", "SPCC1919.11", "P50527", "SPBC1604.14c", "Q9USZ7", "SPBC11G11.02c", "Q10161", "SPAC26A3.05", "Q10056", "SPAC1F5.09c", "Q01112", "SPAC110.03", "Q9UTG2", "SPAC1805.15c", "O14188", "SPAC4F8.13c", "O94685", "SPBC83.01", "O14326", "SPBC16E9.11c" ] }, "reaction_10757398": { "compartment": "compartment_70101", "id": "reaction_10757398", "reactome": "R-SPO-9626880", "name": "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757392", "species_113592" ], "products": [ "species_29370", "species_10757370" ], "modifiers": [ [ "species_10739926", "catalyst" ] ], "additional_components": [ "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "SPAC24B11.06c" ] }, "reaction_10756800": { "compartment": "compartment_876", "id": "reaction_10756800", "reactome": "R-SPO-9013161", "name": "CDC42 GAPs stimulate CDC42 GTPase activity", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_10738231" ], "products": [ "species_10756776", "species_29372" ], "modifiers": [ [ "species_10756797", "catalyst" ] ], "additional_components": [ "Q01112", "SPAC110.03", "species_29438", "species_29420", "Q01112", "SPAC110.03", "O74335", "SPBC17F3.01c", "O94466", "SPBC23G7.08c", "O43027", "SPBC354.13", "Q9P3B1", "SPAC1565.02c" ] }, "reaction_10757395": { "compartment": "compartment_70101", "id": "reaction_10757395", "reactome": "R-SPO-9626832", "name": "MAPK1 or MAPK3 phosphorylates NCF1 at Ser345", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757392", "species_113592" ], "products": [ "species_29370", "species_10757370" ], "modifiers": [ [ "species_10744304", "catalyst" ] ], "additional_components": [ "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10757874": { "compartment": "compartment_876", "id": "reaction_10757874", "reactome": "R-SPO-9693207", "name": "RHOD translocates to the mitochondrial outer membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756831" ], "products": [ "species_10757872" ], "modifiers": [], "additional_components": [ "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438", "Q9HE04", "SPAC20H4.11c", "Q09914", "SPAC1F7.04", "O13928", "SPAC23C4.08", "Q874R1", "SPAC16A10.04", "Q10133", "SPAC16.01", "species_29438" ] }, "reaction_10757388": { "compartment": "compartment_70101", "id": "reaction_10757388", "reactome": "R-SPO-9626817", "name": "PKC phosphorylates NCF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10757374" ], "products": [ "species_29370", "species_10757386" ], "modifiers": [ [ "species_10745378", "catalyst" ] ], "additional_components": [ "O74448", "SPCC16C4.03", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "O74448", "SPCC16C4.03", "P40996", "SPAC22H10.07", "O42854", "SPAC23A1.17", "P36583", "SPBC12D12.04c", "P36582", "SPAC17G8.14c" ] }, "reaction_10749638": { "compartment": "compartment_12045", "id": "reaction_10749638", "reactome": "R-SPO-5693761", "name": "FA2H hydroxylates CERA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29368", "species_428256" ], "products": [ "species_5693768", "species_29356" ], "modifiers": [ [ "species_10749635", "catalyst" ] ], "additional_components": [ "SPAC19G12.08" ] }, "reaction_10739067": { "compartment": "compartment_70101", "id": "reaction_10739067", "reactome": "R-SPO-428664", "name": "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428275", "species_29356" ], "products": [ "species_428694", "species_29372" ], "modifiers": [ [ "species_10739064", "catalyst" ] ], "additional_components": [ "Q9P6N5", "SPAC823.11" ] }, "reaction_10739084": { "compartment": "compartment_70101", "id": "reaction_10739084", "reactome": "R-SPO-428701", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10739064", "catalyst" ] ], "additional_components": [ "Q9P6N5", "SPAC823.11" ] }, "reaction_10739049": { "compartment": "compartment_70101", "id": "reaction_10739049", "reactome": "R-SPO-428259", "name": "dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_428206", "species_29368", "species_428126" ], "products": [ "species_29356", "species_428218", "species_428256" ], "modifiers": [ [ "species_10739046", "catalyst" ] ], "additional_components": [ "species_29364", "species_29362", "species_29366", "species_113526", "SPBC3B8.07c" ] }, "reaction_10739027": { "compartment": "compartment_70101", "id": "reaction_10739027", "reactome": "R-SPO-428185", "name": "sphinganine + stearyl-CoA => dihydroceramide + CoASH", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_428139" ], "products": [ "species_76194", "species_428126" ], "modifiers": [ [ "species_10739024", "catalyst" ] ], "additional_components": [ "O59735", "SPBC3E7.15c", "P78970", "SPAC1A6.09c" ] }, "reaction_10739055": { "compartment": "compartment_70101", "id": "reaction_10739055", "reactome": "R-SPO-428273", "name": "SPHK1 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10738404", "catalyst" ] ], "additional_components": [ "SPAC4A8.07c" ] }, "reaction_10739041": { "compartment": "compartment_70101", "id": "reaction_10739041", "reactome": "R-SPO-428214", "name": "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428163", "species_113592" ], "products": [ "species_29370", "species_428275" ], "modifiers": [ [ "species_10739038", "catalyst" ] ], "additional_components": [ "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04" ] }, "reaction_10739052": { "compartment": "compartment_70101", "id": "reaction_10739052", "reactome": "R-SPO-428260", "name": "dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_29368", "species_428126" ], "products": [ "species_29366", "species_9025544", "species_29356" ], "modifiers": [ [ "species_10739046", "catalyst" ] ], "additional_components": [ "SPBC3B8.07c" ] }, "reaction_10757901": { "compartment": "compartment_70101", "id": "reaction_10757901", "reactome": "R-SPO-9695949", "name": "SPHK2 phosphorylates SPG to S1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_428193" ], "products": [ "species_29370", "species_428203" ], "modifiers": [ [ "species_10739036", "catalyst" ], [ "species_10757899", "inhibitor" ] ], "additional_components": [ "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04", "LigandDisplayForward?ligandId=6625", "LigandDisplayForward?ligandId=10641", "O14159", "SPAC4A8.07c", "O94624", "SPBC1347.04", "LigandDisplayForward?ligandId=10219", "LigandDisplayForward?ligandId=6624" ] }, "reaction_10739081": { "compartment": "compartment_70101", "id": "reaction_10739081", "reactome": "R-SPO-428696", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_428203", "species_29356" ], "products": [ "species_428682", "species_29372" ], "modifiers": [ [ "species_10739072", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10739075": { "compartment": "compartment_984", "id": "reaction_10739075", "reactome": "R-SPO-428690", "name": "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_419305", "species_109276" ], "products": [ "species_109277", "species_428662" ], "modifiers": [ [ "species_10739072", "catalyst" ] ], "additional_components": [ "SPBC409.18" ] }, "reaction_10740345": { "compartment": "compartment_70101", "id": "reaction_10740345", "reactome": "R-SPO-879459", "name": "F-actin capping protein is a heterodimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740341", "species_10740336" ], "products": [ "species_10740343" ], "modifiers": [], "additional_components": [ "SPAC631.01c", "SPAC12B10.07", "Q9HGP5", "SPAC631.01c", "Q10434", "SPAC12B10.07" ] }, "reaction_10741463": { "compartment": "compartment_7660", "id": "reaction_10741463", "reactome": "R-SPO-994106", "name": "HP1 alpha binds Histone H3K9(me)3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741456", "species_10741459" ], "products": [ "species_10741461" ], "modifiers": [], "additional_components": [ "SPAC664.01c", "SPAC1834.04", "P09988", "SPAC1834.04", "P40381", "SPAC664.01c" ] }, "reaction_10741481": { "compartment": "compartment_74700", "id": "reaction_10741481", "reactome": "R-SPO-1011576", "name": "EHD proteins interact with Rabenosyn-5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741477", "species_10741468" ], "products": [ "species_10741479" ], "modifiers": [], "additional_components": [ "SPAC17G6.08", "SPAC16E8.01", "O13786", "SPAC17G6.08", "O13736", "SPAC16E8.01" ] }, "reaction_10741454": { "compartment": "compartment_70101", "id": "reaction_10741454", "reactome": "R-SPO-992708", "name": "Dual-specific AKAPs bind type I and II PKA regulatory subunits", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734228", "species_10741450" ], "products": [ "species_10741452" ], "modifiers": [], "additional_components": [ "P36600", "SPAC8C9.03", "P40376", "SPBC106.10", "SPAC23G3.05c", "Q9P7S8", "SPAC23G3.05c", "P36600", "SPAC8C9.03", "P40376", "SPBC106.10" ] }, "reaction_10741445": { "compartment": "compartment_17906", "id": "reaction_10741445", "reactome": "R-SPO-992703", "name": "Mitofusins trans-interact linking mitochondria prior to fusion", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10741439" ], "products": [ "species_10741443" ], "modifiers": [], "additional_components": [ "SPBC1706.03", "Q9USY7", "SPBC1706.03" ] }, "reaction_10750893": { "compartment": "compartment_7660", "id": "reaction_10750893", "reactome": "R-SPO-6791222", "name": "21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750858" ], "products": [ "species_10750866" ], "modifiers": [ [ "species_10750890", "catalyst" ], [ "species_10750562", "catalyst" ], [ "species_10750878", "catalyst" ], [ "species_10750574", "catalyst" ] ], "additional_components": [ "O59675", "SPBC29A3.12", "Q9HDY4", "SPAPB1A10.06c", "O60055", "SPBC56F2.04", "Q9USN3", "SPCC16A11.02", "O94365", "SPBC428.19c", "O60179", "SPBC23E6.04c", "Q09775", "SPAC22F3.08c", "O74340", "SPBC1A4.07c", "O60161", "SPBC19F5.02c", "Q9P6P2", "SPAC823.04", "P35551", "SPBC2D10.10c", "O60188", "SPBC244.02c", "Q10107", "SPAC18G6.07c", "O74835", "SPCC1183.07", "Q9C1X1", "SPBC713.04c", "Q10101", "SPAC18G6.14c", "Q10106", "SPAC18G6.06", "P0CT56", "SPAC3H5.05c", "P78750", "SPBC29A3.06", "O74690", "SPAC607.03c", "Q9P6N8", "SPAC823.08c", "O94683", "SPBC776.17", "O94676", "SPBC776.08c", "O94653", "SPBC31E1.06", "O13835", "SPAC19D5.05c", "Q9HE11", "SPAC20H4.01", "O13823", "SPAC19A8.07c", "P0CT57", "SPBC18H10.13", "Q9P4X3", "SPAC959.03c", "O14053", "SPCC1672.07", "P87137", "SPAC57A7.06", "O94372", "SPBC1604.06c", "O43051", "SPBC3F6.04c", "O94514", "SPBC646.10c", "Q9P7S7", "SPAC23G3.06", "O74974", "SPCC1827.01c", "Q09757", "SPAC24H6.07", "O13610", "SPBC32H8.04c", "O74777", "SPBC25B2.05", "Q1MTS0", "SPBC3B8.09", "O13878", "SPAC1B3.13", "O13910", "SPAC23C11.03", "Q9P7C0", "SPAC2E1P5.05", "Q09870", "SPAC12G12.06c", "O74892", "SPCC576.08c", "Q9HGM5", "SPBC543.06c", "P87177", "SPBC3D6.12", "Q9C0Z7", "SPAPB1E7.12", "O59675", "SPBC29A3.12", "Q9HDY4", "SPAPB1A10.06c", "O60055", "SPBC56F2.04", "Q9USN3", "SPCC16A11.02", "O94365", "SPBC428.19c", "O60179", "SPBC23E6.04c", "Q09775", "SPAC22F3.08c", "O74340", "SPBC1A4.07c", "O60161", "SPBC19F5.02c", "Q9P6P2", "SPAC823.04", "P35551", "SPBC2D10.10c", "O60188", "SPBC244.02c", "Q10107", "SPAC18G6.07c", "O74835", "SPCC1183.07", "Q9C1X1", "SPBC713.04c", "Q10101", "SPAC18G6.14c", "Q10106", "SPAC18G6.06", "P0CT56", "SPAC3H5.05c", "P78750", "SPBC29A3.06", "O74690", "SPAC607.03c", "Q9P6N8", "SPAC823.08c", "O94683", "SPBC776.17", "O94676", "SPBC776.08c", "O94653", "SPBC31E1.06", "O13835", "SPAC19D5.05c", "Q9HE11", "SPAC20H4.01", "O13823", "SPAC19A8.07c", "P0CT57", "SPBC18H10.13", "Q9P4X3", "SPAC959.03c", "O14053", "SPCC1672.07", "P87137", "SPAC57A7.06", "O94372", "SPBC1604.06c", "O43051", "SPBC3F6.04c", "O94514", "SPBC646.10c", "Q9P7S7", "SPAC23G3.06", "O74974", "SPCC1827.01c", "Q09757", "SPAC24H6.07", "O13610", "SPBC32H8.04c", "O74777", "SPBC25B2.05", "Q1MTS0", "SPBC3B8.09", "O13878", "SPAC1B3.13", "O13910", "SPAC23C11.03", "Q9P7C0", "SPAC2E1P5.05", "Q09870", "SPAC12G12.06c", "O74892", "SPCC576.08c", "Q9HGM5", "SPBC543.06c", "P87177", "SPBC3D6.12", "Q9C0Z7", "SPAPB1E7.12", "O14232", "SPAC6F12.16c", "O74918", "SPCC757.08", "O60124", "SPBC16G5.10", "O42872", "SPAC3G9.10c", "O74469", "SPCC1739.07", "Q10146", "SPAC1F3.01", "Q9P7R3", "SPBC211.08c", "O59821", "SPCC1840.11", "Q09704", "SPAC2F7.14c", "O14076", "SPACUNK4.11c", "O42894", "SPBC115.01c", "Q10205", "SPBC17D1.03c", "O13903", "SPAC22A12.12c", "SPAC6F12.16c", "SPBC115.01c", "SPAC1F3.01" ] }, "reaction_10751111": { "compartment": "compartment_70101", "id": "reaction_10751111", "reactome": "R-SPO-6791223", "name": "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10751081", "species_10751079" ], "products": [ "species_10751095", "species_10751085", "species_10751089", "species_10751103", "species_10751083", "species_10751087", "species_10751081", "species_10751093", "species_10751097", "species_10751091", "species_10731692" ], "modifiers": [ [ "species_10751087", "catalyst" ], [ "species_10751097", "catalyst" ], [ "species_10751109", "catalyst" ], [ "species_10751103", "catalyst" ] ], "additional_components": [ "SPAC10F6.10", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "Q10312", "SPAC6C3.09", "P40236", "SPAC23C4.12", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "P87120", "SPAC3A12.04c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "Q9P7W5", "SPBC1703.05", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "P40235", "SPBC3H7.15", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT64", "SPBC18H10.14", "P0CT57", "SPBC18H10.13", "O60071", "SPBC13G1.09", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P0CT58", "SPAC22A12.04c", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "Q9UTK0", "SPAC1486.09", "O94715", "SPCC1393.03", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "Q9Y813", "SPBC1105.16c", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "Q10191", "SPAC3F10.17", "P87158", "SPBC19F8.08", "P0CT76", "SPBP4H10.13", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CT80", "SPCC285.15c", "Q9UTG4", "SPAC1805.11c", "O14044", "SPAC2C4.11c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O13614", "SPBP22H7.08", "O13956", "SPAC23H4.15", "Q9UTQ6", "SPAC1071.07c", "Q9P4W9", "SPAC959.07", "O74172", "SPBC3D6.15", "O42650", "SPAC10F6.10", "SPAC10F6.10", "SPAC3F10.17", "SPAC2C4.11c", "P40235", "SPBC3H7.15", "P40236", "SPAC23C4.12", "SPBC13G1.09", "SPAC1486.09", "SPAC10F6.10", "SPAC23H4.15", "SPBC3H7.15", "SPBC1703.05", "O59675", "SPBC29A3.12", "Q9P7B2", "SPAC521.05", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "Q09781", "SPAC13G6.02c", "P0CT74", "SPAC144.11", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "Q9P546", "SPAPJ698.02c", "O74329", "SPBC1685.09", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P87158", "SPBC19F8.08", "P0CT56", "SPAC3H5.05c", "P0CH07", "SPAC1805.12c", "P0C016", "SPAC6G10.11c", "P0CT76", "SPBP4H10.13", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O74893", "SPCC576.09", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "Q9P3T6", "SPAC328.10c", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P0CT80", "SPCC285.15c", "P0CT64", "SPBC18H10.14", "Q9UTG4", "SPAC1805.11c", "P0CT57", "SPBC18H10.13", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "P0CT58", "SPAC22A12.04c", "O13614", "SPBP22H7.08", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O94715", "SPCC1393.03", "Q9UTQ6", "SPAC1071.07c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "P0CT67", "SPCC1259.01c", "Q9P4W9", "SPAC959.07", "O74892", "SPCC576.08c", "Q9C0Z7", "SPAPB1E7.12", "O74172", "SPBC3D6.15", "P0CT66", "SPBC16D10.11c", "SPAC1486.09", "SPBC3H7.15", "SPAC26A3.06", "P40235", "SPBC3H7.15", "P40236", "SPAC23C4.12" ] }, "reaction_10750611": { "compartment": "compartment_7660", "id": "reaction_10750611", "reactome": "R-SPO-6791219", "name": "32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10750595" ], "products": [ "species_10750552" ], "modifiers": [ [ "species_10750593", "catalyst" ], [ "species_10750543", "catalyst" ], [ "species_10750609", "catalyst" ], [ "species_10750548", "catalyst" ] ], "additional_components": [ "Q9UU96", "SPCC830.03", "O42936", "SPBC16C6.12c", "Q9URY0", "SPAC890.04c", "O74399", "SPBC4F6.13c", "O94718", "SPCC1393.06c", "P87243", "SPCC4G3.18", "O42957", "SPBC19G7.09", "Q10272", "SPAC13G7.08c", "O60164", "SPBC19F5.05c", "Q9UU96", "SPCC830.03", "O42936", "SPBC16C6.12c", "O94718", "SPCC1393.06c", "P87243", "SPCC4G3.18", "O42957", "SPBC19G7.09", "Q10272", "SPAC13G7.08c", "Q9URY0", "SPAC890.04c", "O74399", "SPBC4F6.13c", "O60164", "SPBC19F5.05c", "SPBC16C6.12c", "O13802", "SPAC17H9.05", "O74791", "SPBC26H8.08c", "O60164", "SPBC19F5.05c", "SPCC830.03" ] }, "reaction_10732544": { "compartment": "compartment_70101", "id": "reaction_10732544", "reactome": "R-SPO-73798", "name": "AICAR + 10-Formyl-THF => FAICAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111409", "species_419151" ], "products": [ "species_111427", "species_111355" ], "modifiers": [ [ "species_10732538", "catalyst" ] ], "additional_components": [ "O74928", "SPCPB16A4.03c" ] }, "reaction_10757804": { "compartment": "compartment_70101", "id": "reaction_10757804", "reactome": "R-SPO-9678749", "name": "IMPDH tetramers binds IMPDH inhibitors", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732525", "species_9678719" ], "products": [ "species_10732528" ], "modifiers": [], "additional_components": [ "O14344", "SPBC2F12.14c", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842", "O14344", "SPBC2F12.14c", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842" ] }, "reaction_10732518": { "compartment": "compartment_70101", "id": "reaction_10732518", "reactome": "R-SPO-73792", "name": "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111584", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29404", "species_111294", "species_76577", "species_113578" ], "modifiers": [ [ "species_10732515", "catalyst" ] ], "additional_components": [ "SPBC2F12.14c" ] }, "reaction_10732530": { "compartment": "compartment_70101", "id": "reaction_10732530", "reactome": "R-SPO-73794", "name": "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29360", "species_29356" ], "products": [ "species_73473", "species_70106", "species_111584" ], "modifiers": [ [ "species_10732525", "catalyst" ], [ "species_10732528", "inhibitor" ], [ "species_111584", "inhibitor" ] ], "additional_components": [ "O14344", "SPBC2F12.14c", "O14344", "SPBC2F12.14c", "LigandDisplayForward?ligandId=6832", "LigandDisplayForward?ligandId=6845", "LigandDisplayForward?ligandId=6842" ] }, "reaction_10734091": { "compartment": "compartment_70101", "id": "reaction_10734091", "reactome": "R-SPO-111524", "name": "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29602", "species_29438", "species_29448" ], "products": [ "species_70106", "species_35141", "species_29372", "species_29420" ], "modifiers": [ [ "species_10734088", "catalyst" ], [ "species_29420", "inhibitor" ], [ "species_113578", "inhibitor" ], [ "species_35141", "inhibitor" ], [ "species_30014", "inhibitor" ] ], "additional_components": [ "Q02787", "SPAC144.03", "species_29926" ] }, "reaction_10732576": { "compartment": "compartment_70101", "id": "reaction_10732576", "reactome": "R-SPO-73814", "name": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29424", "species_113592", "species_111292" ], "products": [ "species_70106", "species_29370", "species_111338", "species_29372" ], "modifiers": [ [ "species_10732559", "catalyst" ] ], "additional_components": [ "SPBC405.01" ] }, "reaction_10732570": { "compartment": "compartment_70101", "id": "reaction_10732570", "reactome": "R-SPO-73812", "name": "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111354", "species_29472", "species_113592", "species_29356" ], "products": [ "species_70106", "species_29370", "species_111369", "species_29404", "species_29372" ], "modifiers": [ [ "species_10732567", "catalyst" ] ], "additional_components": [ "SPAC6F12.10c" ] }, "reaction_10732573": { "compartment": "compartment_70101", "id": "reaction_10732573", "reactome": "R-SPO-73813", "name": "GAR + 10-Formyl-THF => FGAR + THF", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111338", "species_419151" ], "products": [ "species_70106", "species_111354", "species_111355" ], "modifiers": [ [ "species_10732559", "catalyst" ] ], "additional_components": [ "SPBC405.01" ] }, "reaction_10732541": { "compartment": "compartment_70101", "id": "reaction_10732541", "reactome": "R-SPO-73797", "name": "FAICAR => IMP + H2O", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111427" ], "products": [ "species_29602", "species_29356" ], "modifiers": [ [ "species_10732538", "catalyst" ] ], "additional_components": [ "O74928", "SPCPB16A4.03c" ] }, "reaction_10732554": { "compartment": "compartment_70101", "id": "reaction_10732554", "reactome": "R-SPO-73800", "name": "SAICAR => AICAR + Fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111399" ], "products": [ "species_29586", "species_111409" ], "modifiers": [ [ "species_10732551", "catalyst" ] ], "additional_components": [ "O60105", "SPBC14F5.09c" ] }, "reaction_10732578": { "compartment": "compartment_70101", "id": "reaction_10732578", "reactome": "R-SPO-73828", "name": "adenylosuccinate => adenosine 5'-monophosphate + fumarate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_35141" ], "products": [ "species_29586", "species_76577" ], "modifiers": [ [ "species_10732551", "catalyst" ] ], "additional_components": [ "O60105", "SPBC14F5.09c" ] }, "reaction_10732562": { "compartment": "compartment_70101", "id": "reaction_10732562", "reactome": "R-SPO-73810", "name": "FGAM + ATP => AIR + ADP + Pi", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_111369" ], "products": [ "species_70106", "species_29370", "species_111370", "species_29372" ], "modifiers": [ [ "species_10732559", "catalyst" ] ], "additional_components": [ "SPBC405.01" ] }, "reaction_10739670": { "compartment": "compartment_7660", "id": "reaction_10739670", "reactome": "R-SPO-448955", "name": "Phosphorylation of MEF2 proteins by p38", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10739644", "species_10739654" ], "products": [ "species_113582", "species_10739667" ], "modifiers": [ [ "species_10739654", "catalyst" ] ], "additional_components": [ "SPBC317.01", "Q09892", "SPAC24B11.06c", "Q09892", "SPAC24B11.06c", "Q9HGP0", "SPBC317.01", "Q09892", "SPAC24B11.06c" ] }, "reaction_10754565": { "compartment": "compartment_12045", "id": "reaction_10754565", "reactome": "R-SPO-8857686", "name": "FITM1, FITM2 bind TAGs", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_549167", "species_10754559" ], "products": [ "species_10754563" ], "modifiers": [], "additional_components": [ "SPBC543.08", "Q9HGM4", "SPBC543.08", "species_549167" ] }, "reaction_10732605": { "compartment": "compartment_5460", "id": "reaction_10732605", "reactome": "R-SPO-73920", "name": "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_73911", "species_113526" ], "products": [ "species_73909", "species_29362", "species_113529" ], "modifiers": [ [ "species_10732592", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10744280": { "compartment": "compartment_7660", "id": "reaction_10744280", "reactome": "R-SPO-3371518", "name": "SIRT1 binds to HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738936", "species_10744242" ], "products": [ "species_10744244" ], "modifiers": [], "additional_components": [ "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O94640", "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06" ] }, "reaction_10747248": { "compartment": "compartment_7660", "id": "reaction_10747248", "reactome": "R-SPO-5682026", "name": "MRN bound to shortened telomeres activates ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747243", "species_29358" ], "products": [ "species_10737781", "species_113582", "species_10747245" ], "modifiers": [ [ "species_10747243", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "SPCC23B6.03c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744330": { "compartment": "compartment_70101", "id": "reaction_10744330", "reactome": "R-SPO-3371590", "name": "HSP70 binds to HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744328", "species_10744326" ], "products": [ "species_10744167" ], "modifiers": [], "additional_components": [ "O59855", "SPCC1739.13", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q09912", "SPCC830.07c", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11" ] }, "reaction_10745619": { "compartment": "compartment_7660", "id": "reaction_10745619", "reactome": "R-SPO-5333051", "name": "RPA1 binds HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10729504", "species_10744252" ], "products": [ "species_10745617" ], "modifiers": [], "additional_components": [ "Q92373", "SPCC1753.01c", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q92373", "SPCC1753.01c", "Q02953", "SPAC2E12.02", "Q92374", "SPCC23B6.05c", "Q92372", "SPBC660.13c" ] }, "reaction_10746067": { "compartment": "compartment_70101", "id": "reaction_10746067", "reactome": "R-SPO-5618107", "name": "ATP binding to HSP90 triggers conformation change", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10744276" ], "products": [ "species_10746061" ], "modifiers": [], "additional_components": [ "O59855", "SPCC1739.13", "P41887", "SPAC926.04c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q9USI5", "SPCC645.14c", "O59855", "SPCC1739.13", "P41887", "SPAC926.04c", "species_29370", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q9USI5", "SPCC645.14c" ] }, "reaction_10747237": { "compartment": "compartment_7660", "id": "reaction_10747237", "reactome": "R-SPO-5682020", "name": "MRN complex binds shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_3785706", "species_10733251" ], "products": [ "species_10747220" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744259": { "compartment": "compartment_7660", "id": "reaction_10744259", "reactome": "R-SPO-3371467", "name": "SIRT1 deacetylates HSF1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113518", "species_427523", "species_10744244" ], "products": [ "species_10738936", "species_427498", "species_427497", "species_10744256" ], "modifiers": [ [ "species_10744244", "catalyst" ] ], "additional_components": [ "O94640", "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "SPBC16D10.07c", "O59855", "SPCC1739.13", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O94640", "SPBC16D10.07c", "O14283", "SPAC8C9.14", "O59855", "SPCC1739.13", "Q02953", "SPAC2E12.02", "Q09912", "SPCC830.07c", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06" ] }, "reaction_10744307": { "compartment": "compartment_70101", "id": "reaction_10744307", "reactome": "R-SPO-3371531", "name": "Constitutive phosphorylation by pERK1/2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10744185" ], "products": [ "species_29370", "species_10744298" ], "modifiers": [ [ "species_10744304", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "P27638", "SPAC31G5.09c", "Q92398", "SPBC119.08" ] }, "reaction_10744172": { "compartment": "compartment_70101", "id": "reaction_10744172", "reactome": "R-SPO-3371422", "name": "ATP hydrolysis by HSP70", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744167" ], "products": [ "species_10744169", "species_29372" ], "modifiers": [ [ "species_10744167", "catalyst" ], [ "species_10744165", "catalyst" ] ], "additional_components": [ "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_113592", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "Q09912", "SPCC830.07c", "O74752", "SPBC1734.11" ] }, "reaction_10744208": { "compartment": "compartment_70101", "id": "reaction_10744208", "reactome": "R-SPO-3371435", "name": "Constitutive phosphorylation by GSK3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10744185" ], "products": [ "species_29370", "species_10744193" ], "modifiers": [ [ "species_10744205", "catalyst" ] ], "additional_components": [ "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "O14283", "SPAC8C9.14", "Q02953", "SPAC2E12.02", "Q9URT9", "SPBC8D2.01", "Q10452", "SPAC1687.15" ] }, "reaction_10747235": { "compartment": "compartment_7660", "id": "reaction_10747235", "reactome": "R-SPO-5682018", "name": "MRN complex bound to shortened telomeres recruits ATM", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747220", "species_10747231" ], "products": [ "species_10747233" ], "modifiers": [], "additional_components": [ "Q09683", "SPAC13C5.07", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "O74630", "SPCC23B6.03c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10744278": { "compartment": "compartment_70101", "id": "reaction_10744278", "reactome": "R-SPO-3371503", "name": "STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10744264", "species_10744169", "species_10744270" ], "products": [ "species_10744165", "species_10744276" ], "modifiers": [], "additional_components": [ "SPCC645.14c", "O59855", "SPCC1739.13", "Q09912", "SPCC830.07c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "O74752", "SPBC1734.11", "P41887", "SPAC926.04c", "Q09912", "SPCC830.07c", "O74752", "SPBC1734.11", "O59855", "SPCC1739.13", "P41887", "SPAC926.04c", "species_29370", "Q10265", "SPAC13G7.02c", "Q10061", "SPAC1F5.06", "Q9USI5", "SPCC645.14c" ] }, "reaction_10738160": { "compartment": "compartment_12045", "id": "reaction_10738160", "reactome": "R-SPO-381091", "name": "IRE1 dimer autophosphorylates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738152", "species_113592" ], "products": [ "species_10738157", "species_29370" ], "modifiers": [ [ "species_10738152", "catalyst" ] ], "additional_components": [ "O94537", "SPAC167.01", "O94537", "SPAC167.01", "O94537", "SPAC167.01" ] }, "reaction_10738162": { "compartment": "compartment_12045", "id": "reaction_10738162", "reactome": "R-SPO-381109", "name": "IRE1 binds IRE1 forming dimer", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10738150" ], "products": [ "species_10738152" ], "modifiers": [], "additional_components": [ "SPAC167.01", "O94537", "SPAC167.01" ] }, "reaction_10751159": { "compartment": "compartment_7660", "id": "reaction_10751159", "reactome": "R-SPO-6792712", "name": "KAT5 acetylates ATM at shortened telomeres", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10747233", "species_113560" ], "products": [ "species_10747243", "species_2485002" ], "modifiers": [ [ "species_10747233", "catalyst" ] ], "additional_components": [ "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c", "Q10325", "SPAC17G8.13c", "Q09683", "SPAC13C5.07", "O74630", "SPCC23B6.03c", "Q9UTJ8", "SPAC1556.01c", "O43070", "SPBC6B1.09c" ] }, "reaction_10752180": { "compartment": "compartment_70101", "id": "reaction_10752180", "reactome": "R-SPO-6799545", "name": "MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6799540", "species_29356" ], "products": [ "species_429579", "species_6799543" ], "modifiers": [ [ "species_10752177", "catalyst" ] ], "additional_components": [ "Q9UT61", "SPAC513.05", "species_442320" ] }, "reaction_10757491": { "compartment": "compartment_70101", "id": "reaction_10757491", "reactome": "R-SPO-9638127", "name": "PGM1:Mg2+ isomerises G6P to G1P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_30537" ], "products": [ "species_29548" ], "modifiers": [ [ "species_10757486", "catalyst" ] ], "additional_components": [ "O74374", "SPBC32F12.10", "species_29926" ] }, "reaction_10729677": { "compartment": "compartment_70101", "id": "reaction_10729677", "reactome": "R-SPO-70369", "name": "GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29452" ], "products": [ "species_29410" ], "modifiers": [ [ "species_10729674", "catalyst" ] ], "additional_components": [ "Q9HDU3", "SPBPB2B2.12c", "species_113526" ] }, "reaction_10729722": { "compartment": "compartment_70101", "id": "reaction_10729722", "reactome": "R-SPO-70427", "name": "PGM:Mg2+ isomerise G1P to G6P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29548" ], "products": [ "species_30537" ], "modifiers": [ [ "species_10729644", "catalyst" ] ], "additional_components": [ "O74478", "SPCC1840.05c", "species_29926" ] }, "reaction_10757179": { "compartment": "compartment_161320", "id": "reaction_10757179", "reactome": "R-SPO-9036727", "name": "GAA hydrolyzes lysosomal glycogen", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757148", "species_1605715" ], "products": [ "species_1605745", "species_10757158" ], "modifiers": [ [ "species_10757176", "catalyst" ] ], "additional_components": [ "O43062", "SPBC4C3.09", "Q09680", "SPBC4C3.09", "species_113527", "O43061", "SPBC4C3.08", "O43062", "SPBC4C3.09", "Q09680", "SPBC4C3.09", "species_113527", "O43061", "SPBC4C3.08", "Q9C0Y4", "SPAPB24D3.10c", "Q9URX4", "SPAC30D11.01c", "Q09901", "SPAC30D11.01c" ] }, "reaction_10740698": { "compartment": "compartment_70101", "id": "reaction_10740698", "reactome": "R-SPO-927789", "name": "Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10740694", "species_10740674" ], "products": [ "species_10740696" ], "modifiers": [], "additional_components": [ "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "P79015", "SPAC3H5.10", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "species_29420", "Q09127", "SPBC18E5.04", "P08094", "SPBP8B7.06", "P0CT76", "SPBP4H10.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "O74893", "SPCC576.09", "P0CT68", "SPAC3A12.10", "Q9P3T6", "SPAC328.10c", "Q9USR7", "SPBC577.02", "Q9UTG4", "SPAC1805.11c", "Q9P383", "SPBC13A2.01c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O42699", "SPCC1682.14", "P0CT83", "SPCC16C4.13c", "Q9P4W9", "SPAC959.07", "Q9US22", "SPAC1783.08c", "O74172", "SPBC3D6.15", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "Q9P546", "SPAPJ698.02c", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07", "SPAC16C9.06c", "O74718", "SPCC584.04", "Q9URX6", "SPAC890.08", "P05767", "SPCC663.04", "O74329", "SPBC1685.09", "P78946", "SPBC29B5.03c", "Q8TFH1", "SPAPB17E12.13", "P0CH07", "SPAC1805.12c", "O13672", "SPBC29A3.04", "O42706", "SPAC959.08", "Q9UUC1", "SPBC365.03c", "P17477", "SPBC3B9.13c", "P0CT71", "SPBC2F12.07c", "O42848", "SPAC23A1.11", "P79071", "SPCC622.18", "P0CT64", "SPBC18H10.14", "O14388", "SPBC685.07c", "P52822", "SPAC3H5.12c", "Q9UTP0", "SPAC1250.05", "O74391", "SPBC4F6.04", "P59289", "SPAPB17E12.05", "P0CT58", "SPAC22A12.04c", "Q9P784", "SPBC1711.06", "O14277", "SPAC8C9.08", "O94438", "SPAC22H12.04c", "O59865", "SPBC17G9.07", "O74864", "SPCC18.14c", "O94715", "SPCC1393.03", "P0CT67", "SPCC1259.01c", "O74892", "SPCC576.08c", "P0CT79", "SPAC25G10.06", "Q9USW5", "SPBC21B10.10", "P28189", "SPAC6F6.07c", "O14062", "SPCC962.04", "P79015", "SPAC3H5.10", "Q9USX4", "SPBC1921.01c", "Q92354", "SPAC6G9.09c", "O74306", "SPBC11C11.09c", "Q9UTI8", "SPAC15E1.03", "species_29420", "Q09127", "SPBC18E5.04", "P08094", "SPBP8B7.06", "P0CT76", "SPBP4H10.13", "P0CT60", "SPAC3G9.03", "O14339", "SPBC2F12.04", "O74893", "SPCC576.09", "P0CT68", "SPAC3A12.10", "Q9P3T6", "SPAC328.10c", "Q9USR7", "SPBC577.02", "Q9UTG4", "SPAC1805.11c", "Q09820", "SPAC16C9.06c", "Q9P383", "SPBC13A2.01c", "Q09757", "SPAC24H6.07", "P05764", "SPBC18E5.06", "O42699", "SPCC1682.14", "P0CT83", "SPCC16C4.13c", "Q9P4W9", "SPAC959.07", "Q9US22", "SPAC1783.08c", "O74172", "SPBC3D6.15", "Q9P6M8", "SPAC1610.03c", "Q9P7B2", "SPAC521.05", "P0CT74", "SPAC144.11", "O14363", "SPBC30D10.18c", "O94658", "SPBC405.07", "Q9P546", "SPAPJ698.02c", "O42984", "SPBC839.05c", "Q10101", "SPAC18G6.14c", "P0CT56", "SPAC3H5.05c", "P0C016", "SPAC6G10.11c", "P31209", "SPAC57A7.04c", "P0C8R3", "SPAC589.10c", "Q9P7J6", "SPCC24B10.09", "O14317", "SPAC1071.08", "P0CH06", "SPAC11G7.04", "O60128", "SPBC16G5.14c", "P79063", "SPAC1834.01", "Q09668", "SPAC11E3.15", "P0CT57", "SPBC18H10.13", "Q10475", "SPAC17C9.03", "P36584", "SPAPB8E5.06c", "P0CT59", "SPAC5D6.01", "P0CT65", "SPAC664.04c", "P05733", "SPCC1223.05c", "P0CT75", "SPAC23C11.02c", "O74330", "SPBC1685.10", "O60143", "SPBC18H10.12c", "O14253", "SPAC6G10.07", "Q9C0Z7", "SPAPB1E7.12", "P0CT66", "SPBC16D10.11c", "O59675", "SPBC29A3.12", "P0CT77", "SPAC26A3.07c", "Q09781", "SPAC13G6.02c", "P0CT61", "SPCC1322.11", "P35679", "SPBP8B7.03c", "P0CT78", "SPBC17G9.10", "Q10232", "SPAC4G9.16c", "O14069", "SPAC1687.06c", "P87158", "SPBC19F8.08", "P0CT72", "SPBC839.04", "O94238", "SPAC1805.13", "Q9P769", "SPAP7G5.05", "P58234", "SPBC21C3.13", "P0CT73", "SPAC31G5.03", "O74175", "SPAC664.05", "P17476", "SPAC644.15", "O42991", "SPBC839.13c", "P0CT80", "SPCC285.15c", "Q92366", "SPBC776.01", "P0CT69", "SPAC26A3.04", "P0CT84", "SPCC31H12.04c", "O13614", "SPBP22H7.08", "O74904", "SPCC613.05c", "Q9UTQ6", "SPAC1071.07c", "P40372", "SPAC17A5.03", "P0CT70", "SPAC1F7.13c", "P36585", "SPCC5E4.07" ] }, "reaction_10737896": { "compartment": "compartment_70101", "id": "reaction_10737896", "reactome": "R-SPO-351207", "name": "Spermine => N-acetylated spermine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353560", "species_76183" ], "products": [ "species_76194", "species_353575" ], "modifiers": [ [ "species_10737893", "catalyst" ] ], "additional_components": [ "SPAC1002.07c" ] }, "reaction_10730001": { "compartment": "compartment_70101", "id": "reaction_10730001", "reactome": "R-SPO-70634", "name": "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498", "species_113567" ], "products": [ "species_113585", "species_29968" ], "modifiers": [ [ "species_10729998", "catalyst" ] ], "additional_components": [ "SPAC4G9.20c" ] }, "reaction_10729981": { "compartment": "compartment_70101", "id": "reaction_10729981", "reactome": "R-SPO-70599", "name": "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29472", "species_29448", "species_113592", "species_29356" ], "products": [ "species_29404", "species_29642", "species_111294", "species_76577" ], "modifiers": [ [ "species_10729978", "catalyst" ] ], "additional_components": [ "P78753", "SPBC119.10" ] }, "reaction_10756871": { "compartment": "compartment_5460", "id": "reaction_10756871", "reactome": "R-SPO-9013471", "name": "MPST transfers sulfur from 3MPYR to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013199", "species_9012592" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10737898": { "compartment": "compartment_70101", "id": "reaction_10737898", "reactome": "R-SPO-351208", "name": "Spermidine => N-acetylated spermidine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_204635", "species_76183" ], "products": [ "species_76194", "species_353555" ], "modifiers": [ [ "species_10737893", "catalyst" ] ], "additional_components": [ "SPAC1002.07c" ] }, "reaction_10757130": { "compartment": "compartment_70101", "id": "reaction_10757130", "reactome": "R-SPO-9034539", "name": "PXLP-K56-SRR dimer deaminates L-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10756881", "catalyst" ] ], "additional_components": [ "O59791", "SPCC320.14" ] }, "reaction_10756803": { "compartment": "compartment_5460", "id": "reaction_10756803", "reactome": "R-SPO-9013198", "name": "TST transfers sulfur from S2O3(2-) to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1614595", "species_9013199" ], "products": [ "species_9013207", "species_9013191" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10741569": { "compartment": "compartment_70101", "id": "reaction_10741569", "reactome": "R-SPO-1237129", "name": "Acireductone is created", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237176", "species_29356" ], "products": [ "species_70106", "species_1237155", "species_29372" ], "modifiers": [ [ "species_10741566", "catalyst" ] ], "additional_components": [ "species_29926", "Q9P6Q2", "SPAC644.08" ] }, "reaction_10729971": { "compartment": "compartment_5460", "id": "reaction_10729971", "reactome": "R-SPO-70596", "name": "GOT2 dimer deaminates L-Asp", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113594", "species_113553" ], "products": [ "species_113552", "species_113587" ], "modifiers": [ [ "species_10729968", "catalyst" ] ], "additional_components": [ "O94320", "SPBC725.01" ] }, "reaction_10740926": { "compartment": "compartment_70101", "id": "reaction_10740926", "reactome": "R-SPO-977324", "name": "PSPH:Mg2+ dimer dephosphorylates O-P-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_936706" ], "products": [ "species_200736", "species_29372" ], "modifiers": [ [ "species_10740923", "catalyst" ] ], "additional_components": [ "O74382", "SPBC3H7.07c", "species_29926" ] }, "reaction_10742240": { "compartment": "compartment_70101", "id": "reaction_10742240", "reactome": "R-SPO-1614631", "name": "Homocysteine is degraded to oxobutanoate and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369", "species_29356" ], "products": [ "species_1614532", "species_29382", "species_936714" ], "modifiers": [ [ "species_10742218", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10742221": { "compartment": "compartment_70101", "id": "reaction_10742221", "reactome": "R-SPO-1614567", "name": "Excess homocysteine yields homolanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_174369" ], "products": [ "species_1614532", "species_1614594" ], "modifiers": [ [ "species_10742218", "catalyst" ], [ "species_174369", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10740937": { "compartment": "compartment_70101", "id": "reaction_10740937", "reactome": "R-SPO-977333", "name": "PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_977329" ], "products": [ "species_936706", "species_29406" ], "modifiers": [ [ "species_10740934", "catalyst" ] ], "additional_components": [ "Q10349", "SPAC1F12.07" ] }, "reaction_10729901": { "compartment": "compartment_70101", "id": "reaction_10729901", "reactome": "R-SPO-70524", "name": "PXLP-K314-GPT transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29404", "species_29398" ], "products": [ "species_29406", "species_29432" ], "modifiers": [ [ "species_10729896", "catalyst" ] ], "additional_components": [ "Q10334", "SPBC582.08" ] }, "reaction_10741559": { "compartment": "compartment_70101", "id": "reaction_10741559", "reactome": "R-SPO-1237119", "name": "Acireductone is oxidized to MOB", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237155", "species_29368" ], "products": [ "species_1237122", "species_29460" ], "modifiers": [ [ "species_10741556", "catalyst" ] ], "additional_components": [ "species_113531", "O94286", "SPBC887.01" ] }, "reaction_10741654": { "compartment": "compartment_70101", "id": "reaction_10741654", "reactome": "R-SPO-1299507", "name": "Methylthio-ribulose-P = Methylthio-ribose-P", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_1237107" ], "products": [ "species_1237165" ], "modifiers": [ [ "species_10741546", "catalyst" ] ], "additional_components": [ "SPBC23E6.10c" ] }, "reaction_10729947": { "compartment": "compartment_70101", "id": "reaction_10729947", "reactome": "R-SPO-70573", "name": "argininosuccinate <=> fumarate + arginine", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_34575" ], "products": [ "species_29586", "species_29468" ], "modifiers": [ [ "species_10729944", "catalyst" ] ], "additional_components": [ "P50514", "SPBC1539.03c" ] }, "reaction_10757135": { "compartment": "compartment_5460", "id": "reaction_10757135", "reactome": "R-SPO-9034756", "name": "MPST transfers sulfur atom from 3MPYR to form CysS248-MPST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756666", "species_9012592" ], "products": [ "species_10757133", "species_113557" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01", "SPCC4B3.01", "SPCC4B3.01" ] }, "reaction_10740139": { "compartment": "compartment_5460", "id": "reaction_10740139", "reactome": "R-SPO-507749", "name": "PXLP-K341-GPT2 transaminates PYR to form L-Ala", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113557" ], "products": [ "species_113594", "species_379697" ], "modifiers": [ [ "species_10740136", "catalyst" ] ], "additional_components": [ "Q10334", "SPBC582.08" ] }, "reaction_10737914": { "compartment": "compartment_70101", "id": "reaction_10737914", "reactome": "R-SPO-351222", "name": "S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_71284" ], "products": [ "species_353113", "species_113528" ], "modifiers": [ [ "species_10737911", "catalyst" ] ], "additional_components": [ "SPBP4H10.05c" ] }, "reaction_10742237": { "compartment": "compartment_70101", "id": "reaction_10742237", "reactome": "R-SPO-1614614", "name": "Cysteine is degraded to serine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707", "species_29356" ], "products": [ "species_1614532", "species_200736" ], "modifiers": [ [ "species_10742218", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10749651": { "compartment": "compartment_876", "id": "reaction_10749651", "reactome": "R-SPO-5693783", "name": "NAALADases hydrolyse NAAG", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5693762" ], "products": [ "species_29404", "species_5693772" ], "modifiers": [ [ "species_10749648", "catalyst" ] ], "additional_components": [ "O43023", "SPBC354.09c" ] }, "reaction_10755607": { "compartment": "compartment_70101", "id": "reaction_10755607", "reactome": "R-SPO-8876789", "name": "CARNMT1 methylates CARN to Anserine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_6786250", "species_71284" ], "products": [ "species_71285", "species_8876775" ], "modifiers": [ [ "species_10755604", "catalyst" ] ], "additional_components": [ "SPBC1778.07" ] }, "reaction_10730041": { "compartment": "compartment_70101", "id": "reaction_10730041", "reactome": "R-SPO-70692", "name": "ornithine => putrescine + CO2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29498" ], "products": [ "species_29610", "species_113528" ], "modifiers": [ [ "species_10730038", "catalyst" ] ], "additional_components": [ "SPAC144.04c" ] }, "reaction_10729917": { "compartment": "compartment_5460", "id": "reaction_10729917", "reactome": "R-SPO-70555", "name": "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113561", "species_29896", "species_113593" ], "products": [ "species_29676", "species_113548", "species_113581" ], "modifiers": [ [ "species_10729914", "catalyst" ], [ "species_30471", "catalyst" ] ], "additional_components": [ "SPAC22G7.06c" ] }, "reaction_10756873": { "compartment": "compartment_5460", "id": "reaction_10756873", "reactome": "R-SPO-9013533", "name": "MPST transfers sulfur from sulfanegen to HCN to form HSCN", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9013543", "species_9013199" ], "products": [ "species_113557", "species_9013191" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10756884": { "compartment": "compartment_70101", "id": "reaction_10756884", "reactome": "R-SPO-9014741", "name": "PXLP-K56-SRR dimer deaminates D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_376186" ], "products": [ "species_29382", "species_29398", "species_29356" ], "modifiers": [ [ "species_10756881", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "O59791", "SPCC320.14" ] }, "reaction_10729937": { "compartment": "compartment_70101", "id": "reaction_10729937", "reactome": "R-SPO-70569", "name": "arginine + H2O => ornithine + urea [ARG1]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29468", "species_29356" ], "products": [ "species_29498", "species_29514" ], "modifiers": [ [ "species_10729934", "catalyst" ] ], "additional_components": [ "species_113527", "Q10066", "SPAC3H1.07" ] }, "reaction_10729927": { "compartment": "compartment_5460", "id": "reaction_10729927", "reactome": "R-SPO-70560", "name": "carbamoyl phosphate + ornithine => citrulline + orthophosphate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29676", "species_113585" ], "products": [ "species_113548", "species_113567" ], "modifiers": [ [ "species_10729924", "catalyst" ] ], "additional_components": [ "P31317", "SPAC4G9.10" ] }, "reaction_10756887": { "compartment": "compartment_70101", "id": "reaction_10756887", "reactome": "R-SPO-9014766", "name": "PXLP-K56-SRR dimer isomerises L-Ser to D-Ser", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_376186" ], "modifiers": [ [ "species_10756881", "catalyst" ], [ "species_29926", "catalyst" ], [ "species_113592", "catalyst" ] ], "additional_components": [ "O59791", "SPCC320.14" ] }, "reaction_10755833": { "compartment": "compartment_70101", "id": "reaction_10755833", "reactome": "R-SPO-8932980", "name": "SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_200736" ], "products": [ "species_8932979" ], "modifiers": [ [ "species_10755830", "catalyst" ] ], "additional_components": [ "Q9HDY3", "SPAPB1A10.07c" ] }, "reaction_10756669": { "compartment": "compartment_5460", "id": "reaction_10756669", "reactome": "R-SPO-9012721", "name": "MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9012724", "species_9012592" ], "products": [ "species_1614595", "species_113557" ], "modifiers": [ [ "species_10756666", "catalyst" ] ], "additional_components": [ "SPCC4B3.01" ] }, "reaction_10741579": { "compartment": "compartment_70101", "id": "reaction_10741579", "reactome": "R-SPO-1237160", "name": "MTA is cleaved and phosphorylated", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353106", "species_29372" ], "products": [ "species_83951", "species_1237165" ], "modifiers": [ [ "species_10741576", "catalyst" ] ], "additional_components": [ "Q09816", "SPAC16C9.02c" ] }, "reaction_10737906": { "compartment": "compartment_70101", "id": "reaction_10737906", "reactome": "R-SPO-351215", "name": "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_353113", "species_29610" ], "products": [ "species_353106", "species_204635" ], "modifiers": [ [ "species_10737903", "catalyst" ] ], "additional_components": [ "SPBC12C2.07c" ] }, "reaction_10729958": { "compartment": "compartment_70101", "id": "reaction_10729958", "reactome": "R-SPO-70581", "name": "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]", "reversible": "true", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_76213", "species_29404" ], "products": [ "species_29448", "species_29406" ], "modifiers": [ [ "species_10729955", "catalyst" ] ], "additional_components": [ "O42652", "SPAC10F6.13c" ] }, "reaction_10742227": { "compartment": "compartment_70101", "id": "reaction_10742227", "reactome": "R-SPO-1614591", "name": "Excess cysteine yields lanthionine and H2S", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_111707" ], "products": [ "species_1614532", "species_1614582" ], "modifiers": [ [ "species_10742218", "catalyst" ], [ "species_111707", "catalyst" ] ], "additional_components": [ "O42851", "SPAC23A1.14c" ] }, "reaction_10729909": { "compartment": "compartment_5460", "id": "reaction_10729909", "reactome": "R-SPO-70542", "name": "glutamate + acetyl CoA => N-acetyl glutamate + CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113552", "species_113559" ], "products": [ "species_29374", "species_30471" ], "modifiers": [ [ "species_10729906", "catalyst" ], [ "species_374064", "catalyst" ] ], "additional_components": [ "SPAC4G9.09c" ] }, "reaction_10739964": { "compartment": "compartment_5460", "id": "reaction_10739964", "reactome": "R-SPO-452036", "name": "arginine + H2O => ornithine + urea [ARG2]", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113521", "species_374064" ], "products": [ "species_113585", "species_374061" ], "modifiers": [ [ "species_10739961", "catalyst" ] ], "additional_components": [ "species_113527", "Q10066", "SPAC3H1.07", "P37818", "SPBP26C9.02c" ] }, "reaction_10734644": { "compartment": "compartment_7660", "id": "reaction_10734644", "reactome": "R-SPO-156682", "name": "PLK1 phosphorylates NUDC", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113592", "species_10734638" ], "products": [ "species_29370", "species_10734642" ], "modifiers": [ [ "species_10734630", "catalyst" ] ], "additional_components": [ "SPBC19F8.02", "SPBC19F8.02", "SPAC23C11.16" ] }, "reaction_10734452": { "compartment": "compartment_7660", "id": "reaction_10734452", "reactome": "R-SPO-112396", "name": "Separation of elongating transcript from template", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734448" ], "products": [ "species_10734450" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734466": { "compartment": "compartment_7660", "id": "reaction_10734466", "reactome": "R-SPO-113412", "name": "Pol II elongation complex moves on the template as transcript elongates", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10734436" ], "products": [ "species_9757634", "species_10734448" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734438": { "compartment": "compartment_7660", "id": "reaction_10734438", "reactome": "R-SPO-112385", "name": "Addition of nucleotides leads to transcript elongation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10734434" ], "products": [ "species_10732494", "species_10734436" ], "modifiers": [], "additional_components": [ "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "Q9HDW3", "SPBC32F12.15", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "Q12126", "SPBC19F8.07", "O42668", "SPAC27D7.14c", "O74995", "SPCC1682.07", "A0ZWU1", "SPCC1223.10c", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "P36613", "SPBP16F5.02", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O74366", "SPBC30B4.07c", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q09915", "SPAC1F7.01c", "Q10319", "SPAC17G8.07", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P49373", "SPAC20H4.03c", "Q9P376", "SPAC19B12.05c", "Q9USX9", "SPBC1861.07", "O14098", "SPAC2F3.15", "O94267", "SPBP8B7.19", "A0ZWU1", "SPCC1223.10c", "O42668", "SPAC27D7.14c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "species_8870907", "Q09191", "SPAC23C4.15", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9UUE7", "SPBC17G9.02c", "Q9P7K8", "SPBC21C3.16c", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "O94529", "SPBC609.05", "O13877", "SPAC1B3.12c", "O42964", "SPBC19G7.16", "Q09150", "SPBC32F12.02", "O59671", "SPBC29A3.08", "O94667", "SPBC651.09c", "P48011", "SPBC19C2.03", "Q9P6R2", "SPBC13E7.08c", "Q92399", "SPBC14C8.12", "O59748", "SPBC530.13", "Q9Y7V2", "SPCC645.13", "O94436", "SPAC22H12.02", "Q9US06", "SPAC664.03" ] }, "reaction_10734460": { "compartment": "compartment_7660", "id": "reaction_10734460", "reactome": "R-SPO-113407", "name": "DSIF complex binds to RNA Pol II (hypophosphorylated)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10734363", "species_10734299" ], "products": [ "species_10734365" ], "modifiers": [], "additional_components": [ "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q9P7K8", "SPBC21C3.16c", "O13936", "SPAC23C4.19", "Q02061", "SPAC23G3.01", "Q9P7K8", "SPBC21C3.16c", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13936", "SPAC23C4.19", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10734370": { "compartment": "compartment_7660", "id": "reaction_10734370", "reactome": "R-SPO-112383", "name": "Hypophosphorylation of RNA Pol II CTD by FCP1P protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732494", "species_10730702", "species_10734304" ], "products": [ "species_10734363", "species_10732494" ], "modifiers": [ [ "species_10734304", "catalyst" ] ], "additional_components": [ "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "SPAC19B12.05c", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "Q9P376", "SPAC19B12.05c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "SPAC19B12.05c" ] }, "reaction_10742959": { "compartment": "compartment_70101", "id": "reaction_10742959", "reactome": "R-SPO-2161549", "name": "PGH2 is reduced to PGF2a by AKR1C3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_265283" ], "products": [ "species_29366", "species_879535" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10737651": { "compartment": "compartment_70101", "id": "reaction_10737651", "reactome": "R-SPO-265295", "name": "Prostaglandin E synthase isomerizes PGH2 to PGE2", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_265283" ], "products": [ "species_265287" ], "modifiers": [ [ "species_10737648", "catalyst" ] ], "additional_components": [ "SPAC9E9.13" ] }, "reaction_10742962": { "compartment": "compartment_70101", "id": "reaction_10742962", "reactome": "R-SPO-2161614", "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_879629" ], "products": [ "species_29366", "species_2142710" ], "modifiers": [ [ "species_10736196", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10748696": { "compartment": "compartment_70101", "id": "reaction_10748696", "reactome": "R-SPO-5690043", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5690044", "species_29356" ], "products": [ "species_76194", "species_5690064" ], "modifiers": [ [ "species_10748693", "catalyst" ] ], "additional_components": [ "CHEBI:33184", "CHEBI:61907", "species_174602", "CHEBI:59554", "P87304", "SPBC31F10.02" ] }, "reaction_10755098": { "compartment": "compartment_12045", "id": "reaction_10755098", "reactome": "R-SPO-8869206", "name": "PAFAH2 hydrolyses PAF to lyso-PAF and acetate", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_8869214", "species_29356" ], "products": [ "species_8869207", "species_29416" ], "modifiers": [ [ "species_10755095", "catalyst" ] ], "additional_components": [ "SPBC106.11c" ] }, "reaction_10746338": { "compartment": "compartment_70101", "id": "reaction_10746338", "reactome": "R-SPO-5631885", "name": "PRDX1 overoxidizes", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29408", "species_10744090" ], "products": [ "species_29356", "species_10746335" ], "modifiers": [ [ "species_10744090", "catalyst" ] ], "additional_components": [ "O74887", "SPCC576.03c", "O74887", "SPCC576.03c", "O74887", "SPCC576.03c" ] }, "reaction_10735170": { "compartment": "compartment_70101", "id": "reaction_10735170", "reactome": "R-SPO-165179", "name": "Formation of TSC1:TSC2 complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10735151", "species_10735164" ], "products": [ "species_10735168" ], "modifiers": [], "additional_components": [ "SPAC630.13c", "SPAC22F3.13", "Q09778", "SPAC22F3.13", "Q9UUG9", "SPAC630.13c" ] }, "reaction_10757294": { "compartment": "compartment_7660", "id": "reaction_10757294", "reactome": "R-SPO-9613494", "name": "Unwinding of DNA for the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10733310" ], "products": [ "species_164121", "species_113541", "species_10733310" ], "modifiers": [ [ "species_10732494", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07" ] }, "reaction_10733352": { "compartment": "compartment_7660", "id": "reaction_10733352", "reactome": "R-SPO-75869", "name": "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733310" ], "products": [ "species_10733350", "species_10732624", "species_113541" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "SPAC16E8.16", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10734065": { "compartment": "compartment_7660", "id": "reaction_10734065", "reactome": "R-SPO-111264", "name": "Addition of nucleotides between position +11 and +30", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733549" ], "products": [ "species_113541", "species_10733586" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10753227": { "compartment": "compartment_7660", "id": "reaction_10753227", "reactome": "R-SPO-6810233", "name": "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10753215" ], "products": [ "species_113582", "species_10753224" ], "modifiers": [ [ "species_10753215", "catalyst" ] ], "additional_components": [ "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "O14098", "SPAC2F3.15", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "O59748", "SPBC530.13", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "O14098", "SPAC2F3.15", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O59748", "SPBC530.13", "O60076", "SPCC1494.02c", "P36595", "SPCC1020.04c", "O94424", "SPBC1198.13c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "O14098", "SPAC2F3.15", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O74627", "SPBC32F12.06", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "O59748", "SPBC530.13" ] }, "reaction_10733584": { "compartment": "compartment_7660", "id": "reaction_10733584", "reactome": "R-SPO-77069", "name": "RNA Polymerase II CTD (phosphorylated) binds to CE", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733582", "species_10733576" ], "products": [ "species_10733578" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "SPBC2F12.08c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733356": { "compartment": "compartment_7660", "id": "reaction_10733356", "reactome": "R-SPO-75873", "name": "Addition of Nucleotides 5 through 9 on the growing Transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10733350" ], "products": [ "species_10733354", "species_10732699", "species_10732619", "species_10732711", "species_113541" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "O13722", "SPAC15A10.02", "Q09813", "SPAC2G11.14", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "P17871", "SPAC3A11.12c", "O60171", "SPBC21H7.02", "Q9US54", "SPAC1002.04c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "Q09869", "SPAC12G12.05c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "Q9USU9", "SPBC28F2.09", "O74948", "SPCC553.11c", "P79011", "SPCC1672.08c", "Q9P3W1", "SPAC458.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10757296": { "compartment": "compartment_7660", "id": "reaction_10757296", "reactome": "R-SPO-9613497", "name": "Unwinding DNA for the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10732713" ], "products": [ "species_10732713", "species_113541" ], "modifiers": [ [ "species_10732494", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07" ] }, "reaction_10734472": { "compartment": "compartment_7660", "id": "reaction_10734472", "reactome": "R-SPO-113430", "name": "Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733586" ], "products": [ "species_10733586" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733580": { "compartment": "compartment_7660", "id": "reaction_10733580", "reactome": "R-SPO-77068", "name": "Activation of GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733578" ], "products": [ "species_10733578" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733604": { "compartment": "compartment_7660", "id": "reaction_10733604", "reactome": "R-SPO-77073", "name": "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733578", "species_10733594", "species_10733600" ], "products": [ "species_10733602" ], "modifiers": [], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P40997", "SPBC2F12.08c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "SPCC330.10", "SPAC23C4.19", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733415": { "compartment": "compartment_7660", "id": "reaction_10733415", "reactome": "R-SPO-75949", "name": "RNA Polymerase II Promoter Opening: First Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10733340" ], "products": [ "species_113582", "species_113550", "species_10733332" ], "modifiers": [ [ "species_10732494", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O13749", "SPAC16E8.16", "P17871", "SPAC3A11.12c", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07" ] }, "reaction_10733589": { "compartment": "compartment_7660", "id": "reaction_10733589", "reactome": "R-SPO-77071", "name": "Phosphorylation (Ser5) of RNA pol II CTD", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29358", "species_10733586" ], "products": [ "species_113582", "species_10733582" ], "modifiers": [ [ "species_10733586", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O14459", "SPACUNK4.06c", "O74995", "SPCC1682.07", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O94684", "SPBC776.18c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14" ] }, "reaction_10733551": { "compartment": "compartment_7660", "id": "reaction_10733551", "reactome": "R-SPO-76576", "name": "Addition of nucleotides 10 and 11 on the growing transcript: Third Transition", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733354", "species_9757634" ], "products": [ "species_113541", "species_10733549" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74366", "SPBC30B4.07c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10752508": { "compartment": "compartment_7660", "id": "reaction_10752508", "reactome": "R-SPO-6802973", "name": "PLK3 phosphorylates CDC25C", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10732945", "species_29358" ], "products": [ "species_113582", "species_10752503" ], "modifiers": [ [ "species_10752505", "catalyst" ] ], "additional_components": [ "SPAC24H6.05", "SPAC24H6.05", "SPAC23C11.16" ] }, "reaction_10733313": { "compartment": "compartment_7660", "id": "reaction_10733313", "reactome": "R-SPO-75850", "name": "Addition of the third nucleotide on the nascent transcript", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_9757634", "species_10732713" ], "products": [ "species_113541", "species_10733310" ], "modifiers": [ [ "species_10730708", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "P17871", "SPAC3A11.12c", "O13749", "SPAC16E8.16", "Q9US54", "SPAC1002.04c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "Q9USU9", "SPBC28F2.09", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O74462", "SPCC16C4.18c", "O13701", "SPAC13F5.02c", "O60171", "SPBC21H7.02", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "Q09869", "SPAC12G12.05c", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O74319", "SPBC15D4.14", "O13282", "SPCC5E4.03c", "O13877", "SPAC1B3.12c", "O13722", "SPAC15A10.02", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "Q09813", "SPAC2G11.14", "P79011", "SPCC1672.08c", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "Q9P3W1", "SPAC458.07", "O74948", "SPCC553.11c", "O60076", "SPCC1494.02c", "P87121", "SPAC3A12.05c", "O74366", "SPBC30B4.07c", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10757952": { "compartment": "compartment_70101", "id": "reaction_10757952", "reactome": "R-SPO-9705714", "name": "SRD5A3 dehydrogenates TEST to DHTEST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193057" ], "products": [ "species_29366", "species_469662" ], "modifiers": [ [ "species_10744798", "catalyst" ] ], "additional_components": [ "SPAC7D4.09c" ] }, "reaction_10736294": { "compartment": "compartment_17957", "id": "reaction_10736294", "reactome": "R-SPO-194023", "name": "HSD11B2,HSD11B1 dimer oxidise CORT to COR", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_193977" ], "products": [ "species_70106", "species_29364", "species_194035" ], "modifiers": [ [ "species_10736291", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10740318": { "compartment": "compartment_70101", "id": "reaction_10740318", "reactome": "R-SPO-804969", "name": "HSD17B1 hydrogenates E1 to EST17b", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29364", "species_193066" ], "products": [ "species_29366", "species_193132" ], "modifiers": [ [ "species_10740315", "catalyst" ] ], "additional_components": [ "O74628", "SPCC162.03" ] }, "reaction_10736285": { "compartment": "compartment_70101", "id": "reaction_10736285", "reactome": "R-SPO-193961", "name": "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_196366" ], "products": [ "species_193092" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10750043": { "compartment": "compartment_5460", "id": "reaction_10750043", "reactome": "R-SPO-5696822", "name": "AKR1B15 reduces EST17b to E1", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_5696835", "species_113563" ], "products": [ "species_113600", "species_5696848", "species_113529" ], "modifiers": [ [ "species_10750040", "catalyst" ] ], "additional_components": [ "O42888", "SPBC8E4.04", "O13848", "SPBC8E4.04", "Q10494", "SPBC8E4.04" ] }, "reaction_10736362": { "compartment": "compartment_70101", "id": "reaction_10736362", "reactome": "R-SPO-196372", "name": "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_193124", "species_29360" ], "products": [ "species_70106", "species_73473", "species_196366" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10754586": { "compartment": "compartment_70101", "id": "reaction_10754586", "reactome": "R-SPO-8862137", "name": "HSD17B2 oxidises estradiol (E2) to estrone (E1)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29366", "species_176619" ], "products": [ "species_70106", "species_29364", "species_193066" ], "modifiers": [ [ "species_10754583", "catalyst" ] ], "additional_components": [ "Q9URV8", "SPBC106.03", "Q9URX0", "SPBC106.03" ] }, "reaction_10736243": { "compartment": "compartment_70101", "id": "reaction_10736243", "reactome": "R-SPO-193073", "name": "HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29360", "species_176626" ], "products": [ "species_70106", "species_73473", "species_193079" ], "modifiers": [ [ "species_10736238", "catalyst" ] ], "additional_components": [ "O43050", "SPBC3F6.02c" ] }, "reaction_10743335": { "compartment": "compartment_70101", "id": "reaction_10743335", "reactome": "R-SPO-2509831", "name": "ITPA hydrolyses XTP to XMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509848", "species_29356" ], "products": [ "species_70106", "species_111584", "species_111294" ], "modifiers": [ [ "species_10743329", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q9UU89", "SPCC830.10" ] }, "reaction_10743338": { "compartment": "compartment_70101", "id": "reaction_10743338", "reactome": "R-SPO-2509838", "name": "ITPA hydrolyses dITP to dIMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_2509835", "species_29356" ], "products": [ "species_70106", "species_9731659", "species_111294" ], "modifiers": [ [ "species_10743329", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q9UU89", "SPCC830.10" ] }, "reaction_10732747": { "compartment": "compartment_70101", "id": "reaction_10732747", "reactome": "R-SPO-74255", "name": "Guanine + H2O => Xanthine + NH4+", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_70106", "species_29356", "species_83956" ], "products": [ "species_30064", "species_31633" ], "modifiers": [ [ "species_10732744", "catalyst" ] ], "additional_components": [ "species_442320", "O14057", "SPCC1672.03c" ] }, "reaction_10743097": { "compartment": "compartment_70101", "id": "reaction_10743097", "reactome": "R-SPO-2393939", "name": "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_1131972" ], "products": [ "species_73578", "species_76577" ], "modifiers": [ [ "species_10743094", "catalyst" ] ], "additional_components": [ "Q9P791", "SPBP35G2.12", "species_29926" ] }, "reaction_10743332": { "compartment": "compartment_70101", "id": "reaction_10743332", "reactome": "R-SPO-2509827", "name": "ITPA hydrolyses ITP to IMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_2509836" ], "products": [ "species_70106", "species_29602", "species_111294" ], "modifiers": [ [ "species_10743329", "catalyst" ], [ "species_29926", "catalyst" ] ], "additional_components": [ "Q9UU89", "SPCC830.10" ] }, "reaction_10756339": { "compartment": "compartment_70101", "id": "reaction_10756339", "reactome": "R-SPO-8953339", "name": "DNPH1 hydrolyses dGMP", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_29356", "species_109327" ], "products": [ "species_8953344", "species_83956" ], "modifiers": [ [ "species_10756336", "catalyst" ] ], "additional_components": [ "SPCC191.05c" ] }, "reaction_10733620": { "compartment": "compartment_7660", "id": "reaction_10733620", "reactome": "R-SPO-77081", "name": "Formation of the CE:GMP intermediate complex", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_113571", "species_10733610" ], "products": [ "species_10733617", "species_111349" ], "modifiers": [ [ "species_10733610", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "species_29626", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733608": { "compartment": "compartment_7660", "id": "reaction_10733608", "reactome": "R-SPO-77077", "name": "Capping complex formation", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733602", "species_72084", "species_29428" ], "products": [ "species_10733606" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733634": { "compartment": "compartment_7660", "id": "reaction_10733634", "reactome": "R-SPO-77090", "name": "Methylation of GMP-cap by RNA Methyltransferase", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733627", "species_77087" ], "products": [ "species_10732494", "species_10733631", "species_10730700", "species_10733600", "species_77502" ], "modifiers": [ [ "species_10733627", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "O13768", "SPAC17A5.06", "P36613", "SPBP16F5.02", "Q9HDW3", "SPBC32F12.15", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "O94684", "SPBC776.18c", "P26659", "SPAC1D4.12", "O74366", "SPBC30B4.07c", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "P40997", "SPBC2F12.08c", "O74880", "SPCC330.10", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "SPAC23C4.19", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733629": { "compartment": "compartment_7660", "id": "reaction_10733629", "reactome": "R-SPO-77085", "name": "Dissociation of transcript with 5'-GMP from GT", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733622" ], "products": [ "species_10733627" ], "modifiers": [], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733636": { "compartment": "compartment_7660", "id": "reaction_10733636", "reactome": "R-SPO-77094", "name": "Formation of cap binding complex (CBC)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10730619", "species_10730614" ], "products": [ "species_10730621" ], "modifiers": [], "additional_components": [ "SPAC6G10.07", "SPBC13A2.01c", "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07" ] }, "reaction_10733625": { "compartment": "compartment_7660", "id": "reaction_10733625", "reactome": "R-SPO-77083", "name": "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733617" ], "products": [ "species_10733622" ], "modifiers": [ [ "species_10733617", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "species_29626", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "species_29626", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733613": { "compartment": "compartment_7660", "id": "reaction_10733613", "reactome": "R-SPO-77078", "name": "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10733606" ], "products": [ "species_113550", "species_10733610" ], "modifiers": [ [ "species_10733606", "catalyst" ] ], "additional_components": [ "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c", "Q9HDW3", "SPBC32F12.15", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O74880", "SPCC330.10", "Q12126", "SPBC19F8.07", "O74995", "SPCC1682.07", "O14459", "SPACUNK4.06c", "O13768", "SPAC17A5.06", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "O94684", "SPBC776.18c", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "P36613", "SPBP16F5.02", "Q02061", "SPAC23G3.01", "O13936", "SPAC23C4.19", "O94416", "SPCC1620.09c", "P26659", "SPAC1D4.12", "O13877", "SPAC1B3.12c", "P40997", "SPBC2F12.08c", "O13745", "SPAC16E8.11c", "P87303", "SPBC13G1.13", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "O74366", "SPBC30B4.07c" ] }, "reaction_10733638": { "compartment": "compartment_7660", "id": "reaction_10733638", "reactome": "R-SPO-77095", "name": "Recognition and binding of the mRNA cap by the cap-binding complex ", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10730621", "species_10730700" ], "products": [ "species_10730702" ], "modifiers": [], "additional_components": [ "Q9P383", "SPBC13A2.01c", "O14253", "SPAC6G10.07", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14", "Q02061", "SPAC23G3.01", "O94424", "SPBC1198.13c", "P36595", "SPCC1020.04c", "O94416", "SPCC1620.09c", "Q9P383", "SPBC13A2.01c", "O13877", "SPAC1B3.12c", "O14459", "SPACUNK4.06c", "P36594", "SPBC28F2.12", "Q09191", "SPAC23C4.15", "P48011", "SPBC19C2.03", "Q92399", "SPBC14C8.12", "P87123", "SPAC3A12.07", "O14253", "SPAC6G10.07", "P37382", "SPCC1442.10c", "O74635", "SPAPYUG7.04c", "O74825", "SPBC337.14" ] }, "reaction_10742810": { "compartment": "compartment_70616", "id": "reaction_10742810", "reactome": "R-SPO-1955380", "name": "TIMM9:TIMM10 transfers proteins to TIMM22", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10742804", "species_10742802", "species_10742777" ], "products": [ "species_10742808" ], "modifiers": [], "additional_components": [ "SPCC24B10.05", "Q9P7K0", "SPCC24B10.05", "Q9USM7", "SPCC16A11.09c", "Q09188", "SPBC530.10c", "Q9UTE9", "SPAC222.03c", "P87130", "SPAC3A12.16c", "P87146", "SPBC25H2.04c", "SPBC25H2.04c", "Q9P7K0", "SPCC24B10.05", "Q9USM7", "SPCC16A11.09c", "Q09188", "SPBC530.10c", "Q9UTE9", "SPAC222.03c", "P87130", "SPAC3A12.16c", "P87146", "SPBC25H2.04c" ] }, "reaction_10756553": { "compartment": "compartment_5460", "id": "reaction_10756553", "reactome": "R-SPO-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10756545" ], "products": [], "modifiers": [ [ "species_10756550", "catalyst" ] ], "additional_components": [ "O74831", "SPCC1183.03c", "P31317", "SPAC4G9.10", "Q9UTL6", "SPAC144.08", "Q09864", "SPAC12G12.04", "SPBC119.17" ] }, "reaction_10757288": { "compartment": "compartment_70101", "id": "reaction_10757288", "reactome": "R-SPO-9609921", "name": "SGTA binds Tail-anchored protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757284", "species_10757262" ], "products": [ "species_10757286" ], "modifiers": [], "additional_components": [ "O13644", "SPBC8D2.14c", "Q92356", "SPAC6G9.11", "O42646", "SPAC10F6.05c", "O43002", "SPBC2G2.03c", "O60119", "SPBC16G5.05c", "Q9USM6", "SPCC16A11.10c", "Q9USH7", "SPCC825.03c", "Q09827", "SPAC4G8.02c", "O13797", "SPAC1142.02c", "O13644", "SPBC8D2.14c", "Q92356", "SPAC6G9.11", "O42646", "SPAC10F6.05c", "O13797", "SPAC1142.02c", "O43002", "SPBC2G2.03c", "O60119", "SPBC16G5.05c", "Q9USM6", "SPCC16A11.10c", "Q9USH7", "SPCC825.03c", "Q09827", "SPAC4G8.02c" ] }, "reaction_10757305": { "compartment": "compartment_70101", "id": "reaction_10757305", "reactome": "R-SPO-9617595", "name": "SGTA binds mislocalized membrane protein", "reversible": "false", "notes": "This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "reactants": [ "species_10757262", "species_10757280" ], "products": [ "species_10757303" ], "modifiers": [], "additional_components": [ "O13797", "SPAC1142.02c", "SPAC6G9.11", "Q92356", "SPAC6G9.11", "O13797", "SPAC1142.02c" ] } }, "mod_collapsed_pathways": {}, "degree_dictionary": { "reaction_10736615": 5, "species_113592": 256, "species_10736578": 5, "Q10364": 19, "SPAC22E12.14c": 1, "species_179838": 24, "P50530": 19, "SPAC1B9.02c": 1, "species_29370": 212, "species_10736485": 5, "species_10736612": 8, "O14208": 2, "SPAC6B12.03c": 1, "Q09743": 2, "SPBC12C2.02c": 1, "Q9Y7K2": 7, "SPBC216.07c": 1, "O74547": 2, "SPCC777.08c": 1, "O74184": 7, "SPBC21B10.05c": 1, "Q9P7Y9": 2, "SPAPYUG7.02c": 1, "reaction_10736508": 5, "species_10736487": 6, "Q12701": 9, "SPCC576.15c": 3, "species_10736505": 9, "species_10733718": 10, "reaction_10743083": 3, "species_10737088": 5, "reaction_10738460": 5, "species_10738454": 5, 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